An ophthalmoscope is described for electrophysiological research on the retina. It adds to the usual viewing and illuminating beam two stimulating beams whose patterns may also be viewed and photographed. A large region of the mammalian fundus can be surveyed, the eye being in the center of a spherical coordinate system.
The design provides measured adaptive and stimulating parameters over the photopic range, sufficient to study intensity, color, timing, and spatial interaction in the retinal mechanisms. Extension to mesopia and scotopia is possible.
Associated optically and mechanically are devices for locating, holding, and directing the eye and head of anaesthetized cats (or monkeys). The eye holder carries a small micromanipulator to control the direction and feed of microelectrodes. This arrangement provides stable electrical contact with single optic ganglion cells for long periods.
The method does not interfere with normal metabolism and optical functioning of the eye.
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