Abstract

A highly sensitive integrated optical biosensor based on the cascade of a Fabry–Perot cavity laser and a microring resonator is investigated theoretically and experimentally. The free spectral ranges of the microring and the laser cavity are designed to be about the same in order to apply intensity interrogation. The variation of the refractive index of the fluidic sample results in a large shift in the envelope function of the total transmission spectrum of the sensor, and consequently, a large change in the transmitted power. The simple light-source-integrated sensing scheme achieved a high sensitivity of 1000 dB/RIU in the preliminary experiment, demonstrating its principle and potential for low-cost practical applications.

© 2012 IEEE

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2011 (4)

A. Cattoni, P. Ghenuche, A.-M. Haghiri-Gosnet, D. Decanini, J. Chen, J.-L. Pelouard, S. Collin, "λ3/1000 plasmonic nanocavities for biosensing fabricated by soft UV nanoimprint lithography," Nano Lett. 11, 3557-3563 (2011).

T. Claes, W. Bogaerts, P. Bienstman, "Vernier-cascade label-free biosensor with integrated arrayed waveguide grating for wavelength interrogation with low-cost broadband source," Opt. Lett. 36, 3320-3322 (2011).

L. Jin, M. Li, J.-J. He, "Highly-sensitive silicon-on-insulator sensor based on two cascaded micro-rings resonator with Vernier effect," Opt. Commun. 284, 156-159 (2011).

L. Jin, M. Li, J.-J. He, "Optical waveguide double-ring sensor using intensity interrogation with a low-cost broadband source," Opt. Lett. 36, 1128-1130 (2011).

2010 (1)

X. Ma, X. Xu, Z. Zheng, K. Wang, Y. Su, J. Fan, R. Zhang, L. Song, Z. Wang, J. Zhu, "Dynamically modulated intensity interrogation scheme using waveguide coupled surface plasmon resonance sensors," Sens. Actuators A, Phys. 157, 9-14 (2010).

2008 (2)

D.-X. Xu, A. Densmore, A. Delâge, P. Waldron, R. McKinnon, S. Janz, J. Lapointe, G. Lopinski, T. Mischki, E. Post, P. Cheben, J. H. Schmid, "Folded cavity SOI microring sensors for high sensitivity and real time measurement of biomolecular binding," Opt. Exp. 16, 15137-15148 (2008).

A. Densmore, D.-X. Xu, S. Janz, P. Waldron, T. Mischki, G. Lopinski, A. Delâge, J. Lapointe, P. Cheben, B. Lamontagne, J. H. Schmid, "Spiral-path high-sensitivity silicon photonic wire molecular sensor with temperature-independent response," Opt. Lett. 33, 596-598 (2008).

2007 (5)

K. De Vos, I. Bartolozzi, E. Schacht, P. R. Bienstman1, R. Baets, "Silicon-on-insulator microring resonator for sensitive and label-free biosensing," Opt. Exp. 15, 7610-7615 (2007).

A. K. Sharma, R. Jha, B. D. Gupta, "Fiber-optic sensors based on surface plasmon resonance: A comprehensive review," IEEE Sens. J. 7, 1118-1129 (2007).

M. A. Webster, R. M. Pafchek, A. Mitchell, T. L. Koch, "Width dependence of inherent TM-mode lateral leakage loss in silicon-on-insulator ridge waveguide," IEEE Photon. Technol. Lett. 19, 429-431 (2007).

S. S. Saini, C. Stanford, S. M. Lee, J. Park, P. DeShong, W. E. Bentley, M. Dagenais, "Monolayer detection of biochemical agents using etched-core fiber Bragg grating sensors," IEEE Photon. Technol. Lett. 19, 1341-1343 (2007).

P. Cheben, J. H. Schmid, A. Delâge, A. Densmore, S. Janz, B. Lamontagne, J. Lapointe, E. Post, P. Waldron, D.-X. Xu, "A high-resolution silicon-on-insulator arrayed waveguide grating microspectrometer with sub-micrometer aperture waveguides," Opt. Exp. 15, 2299-2306 (2007).

2006 (3)

A. W. Fang, H. Park, O. Cohen, R. Jones, M. J. Paniccia, J. E. Bowers, "Electrically pumped hybrid AlGaInAs-silicon evanescent laser," Opt. Exp. 14, 9203-9210 (2006).

G. Roelkens, D. Van Thourhout, R. Baets, R. Nötzel, M. Smit, "Laser emission and photodetection in an InP/InGaAsP layer integrated on and coupled to a silicon-on-insulator waveguide circuit," Opt. Exp. 14, 8154-8159 (2006).

A. Densmore, D.-X. Xu, P. Waldron, S. Janz, P. Cheben, J. Lapointe, A. Delâge, B. Lamontagne, J. H. Schmid, E. Post, "A silicon-on-insulator photonic wire based evanescent field sensor," IEEE Photon. Technol. Lett. 18, 2520-2522 (2006).

1991 (1)

J. Mohr, B. Anderer, W. Ehrfeld, "Fabrication of a planar grating spectrograph by deep-etch lithography with synchrotron radiation," Sens. Actuators A, Phys. 27, 571-575 (1991).

1988 (1)

Appl. Opt. (1)

IEEE Photon. Technol. Lett. (3)

M. A. Webster, R. M. Pafchek, A. Mitchell, T. L. Koch, "Width dependence of inherent TM-mode lateral leakage loss in silicon-on-insulator ridge waveguide," IEEE Photon. Technol. Lett. 19, 429-431 (2007).

A. Densmore, D.-X. Xu, P. Waldron, S. Janz, P. Cheben, J. Lapointe, A. Delâge, B. Lamontagne, J. H. Schmid, E. Post, "A silicon-on-insulator photonic wire based evanescent field sensor," IEEE Photon. Technol. Lett. 18, 2520-2522 (2006).

S. S. Saini, C. Stanford, S. M. Lee, J. Park, P. DeShong, W. E. Bentley, M. Dagenais, "Monolayer detection of biochemical agents using etched-core fiber Bragg grating sensors," IEEE Photon. Technol. Lett. 19, 1341-1343 (2007).

IEEE Sens. J. (1)

A. K. Sharma, R. Jha, B. D. Gupta, "Fiber-optic sensors based on surface plasmon resonance: A comprehensive review," IEEE Sens. J. 7, 1118-1129 (2007).

Nano Lett. (1)

A. Cattoni, P. Ghenuche, A.-M. Haghiri-Gosnet, D. Decanini, J. Chen, J.-L. Pelouard, S. Collin, "λ3/1000 plasmonic nanocavities for biosensing fabricated by soft UV nanoimprint lithography," Nano Lett. 11, 3557-3563 (2011).

Opt. Commun. (1)

L. Jin, M. Li, J.-J. He, "Highly-sensitive silicon-on-insulator sensor based on two cascaded micro-rings resonator with Vernier effect," Opt. Commun. 284, 156-159 (2011).

Opt. Exp. (5)

P. Cheben, J. H. Schmid, A. Delâge, A. Densmore, S. Janz, B. Lamontagne, J. Lapointe, E. Post, P. Waldron, D.-X. Xu, "A high-resolution silicon-on-insulator arrayed waveguide grating microspectrometer with sub-micrometer aperture waveguides," Opt. Exp. 15, 2299-2306 (2007).

K. De Vos, I. Bartolozzi, E. Schacht, P. R. Bienstman1, R. Baets, "Silicon-on-insulator microring resonator for sensitive and label-free biosensing," Opt. Exp. 15, 7610-7615 (2007).

D.-X. Xu, A. Densmore, A. Delâge, P. Waldron, R. McKinnon, S. Janz, J. Lapointe, G. Lopinski, T. Mischki, E. Post, P. Cheben, J. H. Schmid, "Folded cavity SOI microring sensors for high sensitivity and real time measurement of biomolecular binding," Opt. Exp. 16, 15137-15148 (2008).

A. W. Fang, H. Park, O. Cohen, R. Jones, M. J. Paniccia, J. E. Bowers, "Electrically pumped hybrid AlGaInAs-silicon evanescent laser," Opt. Exp. 14, 9203-9210 (2006).

G. Roelkens, D. Van Thourhout, R. Baets, R. Nötzel, M. Smit, "Laser emission and photodetection in an InP/InGaAsP layer integrated on and coupled to a silicon-on-insulator waveguide circuit," Opt. Exp. 14, 8154-8159 (2006).

Opt. Lett. (3)

Sens. Actuators A, Phys. (2)

X. Ma, X. Xu, Z. Zheng, K. Wang, Y. Su, J. Fan, R. Zhang, L. Song, Z. Wang, J. Zhu, "Dynamically modulated intensity interrogation scheme using waveguide coupled surface plasmon resonance sensors," Sens. Actuators A, Phys. 157, 9-14 (2010).

J. Mohr, B. Anderer, W. Ehrfeld, "Fabrication of a planar grating spectrograph by deep-etch lithography with synchrotron radiation," Sens. Actuators A, Phys. 27, 571-575 (1991).

Other (1)

CRC Handbook of Chemistry and Physics (CRC Press, 2010).

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