Abstract

Time-domain diffuse optical tomography can efficiently reconstruct optical parameters which can be further applied in diagnosing early breast cancer. Nevertheless, the performances of reconstructed imaging are badly influenced by different Jacobian magnitudes of absorption coefficient and reduced scattering coefficient. With the introudction of a relative data type based on generalized pulse spectrum technique, an efficient Jacobian scaling method is proposed. The interrelated simulated validation is also revealed for the enhancing performances.

© 2010 Chinese Optics Letters

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