Abstract

Accurate measurement of the optical properties of biological tissue is very important for optical diagnosis and therapeutics. An artificial neural network (ANN)-based inverse reconstruction method is introduced to determine the optical properties of turbid media, which is based on the reflectance (R) and transmittance (T) of a thin sample measured by a double-integrating-spheres system. The accuracy and robustness of the method has been validated, and the results show that the root mean square errors (RMSEs) of the absorption coefficient \mu a and scattering coefficient \mu' s reconstruction are less than 0.01 cm-1 and 0.02 cm-1, respectively. The algorithm is not only very accurate in the case of a lower albedo (~0.33), but also very robust to the noise of R and T especially for the \mu' s reconstruction.

© 2010 Chinese Optics Letters

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  1. T. J. Pfefer, L. S. Matchette, C. L. Bennett, J. A. Gall, and J. N. Wilke, J. Biomed. Opt. 8, 2 (2003).
  2. G. M. Palmer and N. Ramanujam, Appl. Opt. 45, 5 (2006).
  3. H. Zhao, X. Zhou, J. Liang, and S. Zhang, Chin. Opt. Lett. 6, 12 (2008).
  4. F. Gao, L. Zhang, J. Li, and H. Zhao, Chin. Opt. Lett. 6, 12 (2008).
  5. A. Kienle, M. S. Patterson, R. Bays, G. Wagnieres, and H. Bergh, Appl. Opt. 37, 4 (1998).
  6. N. Rajaram, T. H. Nguyen, and J. W. Tunnell, J. Biomed. Opt. 13, 5 (2008).
  7. J. W. Pickering, S. A. Prahl, N. V. Wieringen, J. F. Beek, H. J. C. M. Sterenborg, and M. J. C. van Gemert, Appl. Opt. 32, 4 (1993).
  8. D. Zhu, W. Lu, S. Zeng, and Q. Luo, J. Biomed. Opt. 12, 6 (2007).
  9. J. S. Dam, T. Dalgaard, P. E. Fabricius, and S. A. Engels, Appl. Opt. 39, 7 (2000).
  10. L. Wang, S. L. Jacques, and L. Zheng, Comput. Meth. Programs Biomed. 47, 131 (1995).
  11. J. S. Judd and J. Stephen, Neural Network Design and the Complexity of Learning (The MIT Press, Cambridge, 1990).
  12. H. J. van Staveren, C. J. M. Moes, J. van Marle, S. A. Prahl, and M. J. C. van Gemert, Appl. Opt. 30, 31 (1991).

2008 (3)

2007 (1)

D. Zhu, W. Lu, S. Zeng, and Q. Luo, J. Biomed. Opt. 12, 6 (2007).

2006 (1)

G. M. Palmer and N. Ramanujam, Appl. Opt. 45, 5 (2006).

2003 (1)

T. J. Pfefer, L. S. Matchette, C. L. Bennett, J. A. Gall, and J. N. Wilke, J. Biomed. Opt. 8, 2 (2003).

2000 (1)

J. S. Dam, T. Dalgaard, P. E. Fabricius, and S. A. Engels, Appl. Opt. 39, 7 (2000).

1998 (1)

A. Kienle, M. S. Patterson, R. Bays, G. Wagnieres, and H. Bergh, Appl. Opt. 37, 4 (1998).

1995 (1)

L. Wang, S. L. Jacques, and L. Zheng, Comput. Meth. Programs Biomed. 47, 131 (1995).

1993 (1)

J. W. Pickering, S. A. Prahl, N. V. Wieringen, J. F. Beek, H. J. C. M. Sterenborg, and M. J. C. van Gemert, Appl. Opt. 32, 4 (1993).

1991 (1)

H. J. van Staveren, C. J. M. Moes, J. van Marle, S. A. Prahl, and M. J. C. van Gemert, Appl. Opt. 30, 31 (1991).

Bays, R.

A. Kienle, M. S. Patterson, R. Bays, G. Wagnieres, and H. Bergh, Appl. Opt. 37, 4 (1998).

Beek, J. F.

J. W. Pickering, S. A. Prahl, N. V. Wieringen, J. F. Beek, H. J. C. M. Sterenborg, and M. J. C. van Gemert, Appl. Opt. 32, 4 (1993).

Bennett, C. L.

T. J. Pfefer, L. S. Matchette, C. L. Bennett, J. A. Gall, and J. N. Wilke, J. Biomed. Opt. 8, 2 (2003).

Bergh, H.

A. Kienle, M. S. Patterson, R. Bays, G. Wagnieres, and H. Bergh, Appl. Opt. 37, 4 (1998).

Dalgaard, T.

J. S. Dam, T. Dalgaard, P. E. Fabricius, and S. A. Engels, Appl. Opt. 39, 7 (2000).

Dam, J. S.

J. S. Dam, T. Dalgaard, P. E. Fabricius, and S. A. Engels, Appl. Opt. 39, 7 (2000).

Engels, S. A.

J. S. Dam, T. Dalgaard, P. E. Fabricius, and S. A. Engels, Appl. Opt. 39, 7 (2000).

Fabricius, P. E.

J. S. Dam, T. Dalgaard, P. E. Fabricius, and S. A. Engels, Appl. Opt. 39, 7 (2000).

Gall, J. A.

T. J. Pfefer, L. S. Matchette, C. L. Bennett, J. A. Gall, and J. N. Wilke, J. Biomed. Opt. 8, 2 (2003).

Gao, F.

Gemert, M. J. C. van

J. W. Pickering, S. A. Prahl, N. V. Wieringen, J. F. Beek, H. J. C. M. Sterenborg, and M. J. C. van Gemert, Appl. Opt. 32, 4 (1993).

Jacques, S. L.

L. Wang, S. L. Jacques, and L. Zheng, Comput. Meth. Programs Biomed. 47, 131 (1995).

Kienle, A.

A. Kienle, M. S. Patterson, R. Bays, G. Wagnieres, and H. Bergh, Appl. Opt. 37, 4 (1998).

Li, J.

Liang, J.

Lu, W.

D. Zhu, W. Lu, S. Zeng, and Q. Luo, J. Biomed. Opt. 12, 6 (2007).

Luo, Q.

D. Zhu, W. Lu, S. Zeng, and Q. Luo, J. Biomed. Opt. 12, 6 (2007).

Matchette, L. S.

T. J. Pfefer, L. S. Matchette, C. L. Bennett, J. A. Gall, and J. N. Wilke, J. Biomed. Opt. 8, 2 (2003).

Moes, C. J. M.

H. J. van Staveren, C. J. M. Moes, J. van Marle, S. A. Prahl, and M. J. C. van Gemert, Appl. Opt. 30, 31 (1991).

Nguyen, T. H.

N. Rajaram, T. H. Nguyen, and J. W. Tunnell, J. Biomed. Opt. 13, 5 (2008).

Palmer, G. M.

G. M. Palmer and N. Ramanujam, Appl. Opt. 45, 5 (2006).

Patterson, M. S.

A. Kienle, M. S. Patterson, R. Bays, G. Wagnieres, and H. Bergh, Appl. Opt. 37, 4 (1998).

Pfefer, T. J.

T. J. Pfefer, L. S. Matchette, C. L. Bennett, J. A. Gall, and J. N. Wilke, J. Biomed. Opt. 8, 2 (2003).

Pickering, J. W.

J. W. Pickering, S. A. Prahl, N. V. Wieringen, J. F. Beek, H. J. C. M. Sterenborg, and M. J. C. van Gemert, Appl. Opt. 32, 4 (1993).

Prahl, S. A.

J. W. Pickering, S. A. Prahl, N. V. Wieringen, J. F. Beek, H. J. C. M. Sterenborg, and M. J. C. van Gemert, Appl. Opt. 32, 4 (1993).

H. J. van Staveren, C. J. M. Moes, J. van Marle, S. A. Prahl, and M. J. C. van Gemert, Appl. Opt. 30, 31 (1991).

Rajaram, N.

N. Rajaram, T. H. Nguyen, and J. W. Tunnell, J. Biomed. Opt. 13, 5 (2008).

Ramanujam, N.

G. M. Palmer and N. Ramanujam, Appl. Opt. 45, 5 (2006).

Sterenborg, H. J. C. M.

J. W. Pickering, S. A. Prahl, N. V. Wieringen, J. F. Beek, H. J. C. M. Sterenborg, and M. J. C. van Gemert, Appl. Opt. 32, 4 (1993).

Tunnell, J. W.

N. Rajaram, T. H. Nguyen, and J. W. Tunnell, J. Biomed. Opt. 13, 5 (2008).

van Gemert, M. J. C.

H. J. van Staveren, C. J. M. Moes, J. van Marle, S. A. Prahl, and M. J. C. van Gemert, Appl. Opt. 30, 31 (1991).

van Marle, J.

H. J. van Staveren, C. J. M. Moes, J. van Marle, S. A. Prahl, and M. J. C. van Gemert, Appl. Opt. 30, 31 (1991).

van Staveren, H. J.

H. J. van Staveren, C. J. M. Moes, J. van Marle, S. A. Prahl, and M. J. C. van Gemert, Appl. Opt. 30, 31 (1991).

Wagnieres, G.

A. Kienle, M. S. Patterson, R. Bays, G. Wagnieres, and H. Bergh, Appl. Opt. 37, 4 (1998).

Wang, L.

L. Wang, S. L. Jacques, and L. Zheng, Comput. Meth. Programs Biomed. 47, 131 (1995).

Wieringen, N. V.

J. W. Pickering, S. A. Prahl, N. V. Wieringen, J. F. Beek, H. J. C. M. Sterenborg, and M. J. C. van Gemert, Appl. Opt. 32, 4 (1993).

Wilke, J. N.

T. J. Pfefer, L. S. Matchette, C. L. Bennett, J. A. Gall, and J. N. Wilke, J. Biomed. Opt. 8, 2 (2003).

Zeng, S.

D. Zhu, W. Lu, S. Zeng, and Q. Luo, J. Biomed. Opt. 12, 6 (2007).

Zhang, L.

Zhang, S.

Zhao, H.

Zheng, L.

L. Wang, S. L. Jacques, and L. Zheng, Comput. Meth. Programs Biomed. 47, 131 (1995).

Zhou, X.

Zhu, D.

D. Zhu, W. Lu, S. Zeng, and Q. Luo, J. Biomed. Opt. 12, 6 (2007).

Appl. Opt. (5)

A. Kienle, M. S. Patterson, R. Bays, G. Wagnieres, and H. Bergh, Appl. Opt. 37, 4 (1998).

J. W. Pickering, S. A. Prahl, N. V. Wieringen, J. F. Beek, H. J. C. M. Sterenborg, and M. J. C. van Gemert, Appl. Opt. 32, 4 (1993).

J. S. Dam, T. Dalgaard, P. E. Fabricius, and S. A. Engels, Appl. Opt. 39, 7 (2000).

H. J. van Staveren, C. J. M. Moes, J. van Marle, S. A. Prahl, and M. J. C. van Gemert, Appl. Opt. 30, 31 (1991).

G. M. Palmer and N. Ramanujam, Appl. Opt. 45, 5 (2006).

Chin. Opt. Lett. (2)

Comput. Meth. Programs Biomed. (1)

L. Wang, S. L. Jacques, and L. Zheng, Comput. Meth. Programs Biomed. 47, 131 (1995).

J. Biomed. Opt. (3)

T. J. Pfefer, L. S. Matchette, C. L. Bennett, J. A. Gall, and J. N. Wilke, J. Biomed. Opt. 8, 2 (2003).

D. Zhu, W. Lu, S. Zeng, and Q. Luo, J. Biomed. Opt. 12, 6 (2007).

N. Rajaram, T. H. Nguyen, and J. W. Tunnell, J. Biomed. Opt. 13, 5 (2008).

Other (1)

J. S. Judd and J. Stephen, Neural Network Design and the Complexity of Learning (The MIT Press, Cambridge, 1990).

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