Abstract

The Raman spectra of DNA in different levels of vitamin C with 10- and 30-min ultraviolet (UV) radiations were reported. The intensity of UV radiation was 18.68 W/m2. The experimental results proved that vitamin C could alone prevent UV radiation from damaging DNA, but the effects depended on the concentration of vitamin C. When the concentration of vitamin C was about 0.08-0.4 mmol/L, vitamin C decreased UV radiation-induced DNA's damage. When the concentration of vitamin C exceeded 0.4 mmol/L, vitamin C accelerated DNA's damage instead. Maybe the reason is that when DNA in aqueous solution is radiated by UV, free radicals come into being, and vitamin C can scavenge free radicals, so vitamin C in lower concentration can protect DNA. The quantity of free radicals is finite, when vitamin C is superfluous, free radicals have been scavenged absolutely and vitamin C is residual. Vitamin C is a strong reductant. When the mixture of DNA and residual vitamin C is radiated by UV, vitamin C reacts with DNA. The more residual vitamin C and the longer time of UV radiation, the more DNA is damaged.

© 2005 Chinese Optics Letters

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2004

J. Li, Y. Liu, W. Sun, and M. Cheng, Chin. J. Public Health (in Chinese) 22, 177 (2004).

P. Moller, M. Viscovich, J. Lykkesfeldt, S. Loft, A. Jensen, and H. E. Polusen, Eur. J. Nutr. 43, 1 (2004).

D. Zhou and W. Ke, Spectroscopy and Spectral Analysis 24, 1370 (2004).

2002

F. Yu, Hygiene Fascicule of Overseas Physic (in Chinese) 29, 141 (2002).

1999

W. Ke, D. Yu, and J. Wu, Spectrochimica Acta Part A 55, 1081 (1999).

C. Jiang, Z. Zeng, and Q. Zhang, Hygiene Fascicule of Overseas Physic (in Chinese) 26, 147 (1999).

1998

H. Zhao, Y. Yu, and Z. Zhang, Chin. Science Bulletin (in Chinese) 43, 955 (1998).

Cheng, M.

J. Li, Y. Liu, W. Sun, and M. Cheng, Chin. J. Public Health (in Chinese) 22, 177 (2004).

Jensen, A.

P. Moller, M. Viscovich, J. Lykkesfeldt, S. Loft, A. Jensen, and H. E. Polusen, Eur. J. Nutr. 43, 1 (2004).

Jiang, C.

C. Jiang, Z. Zeng, and Q. Zhang, Hygiene Fascicule of Overseas Physic (in Chinese) 26, 147 (1999).

Ke, W.

D. Zhou and W. Ke, Spectroscopy and Spectral Analysis 24, 1370 (2004).

W. Ke, D. Yu, and J. Wu, Spectrochimica Acta Part A 55, 1081 (1999).

Li, J.

J. Li, Y. Liu, W. Sun, and M. Cheng, Chin. J. Public Health (in Chinese) 22, 177 (2004).

Liu, Y.

J. Li, Y. Liu, W. Sun, and M. Cheng, Chin. J. Public Health (in Chinese) 22, 177 (2004).

Loft, S.

P. Moller, M. Viscovich, J. Lykkesfeldt, S. Loft, A. Jensen, and H. E. Polusen, Eur. J. Nutr. 43, 1 (2004).

Lykkesfeldt, J.

P. Moller, M. Viscovich, J. Lykkesfeldt, S. Loft, A. Jensen, and H. E. Polusen, Eur. J. Nutr. 43, 1 (2004).

Moller, P.

P. Moller, M. Viscovich, J. Lykkesfeldt, S. Loft, A. Jensen, and H. E. Polusen, Eur. J. Nutr. 43, 1 (2004).

Polusen, H. E.

P. Moller, M. Viscovich, J. Lykkesfeldt, S. Loft, A. Jensen, and H. E. Polusen, Eur. J. Nutr. 43, 1 (2004).

Sun, W.

J. Li, Y. Liu, W. Sun, and M. Cheng, Chin. J. Public Health (in Chinese) 22, 177 (2004).

Viscovich, M.

P. Moller, M. Viscovich, J. Lykkesfeldt, S. Loft, A. Jensen, and H. E. Polusen, Eur. J. Nutr. 43, 1 (2004).

Wu, J.

W. Ke, D. Yu, and J. Wu, Spectrochimica Acta Part A 55, 1081 (1999).

Yu, D.

W. Ke, D. Yu, and J. Wu, Spectrochimica Acta Part A 55, 1081 (1999).

Yu, F.

F. Yu, Hygiene Fascicule of Overseas Physic (in Chinese) 29, 141 (2002).

Yu, Y.

H. Zhao, Y. Yu, and Z. Zhang, Chin. Science Bulletin (in Chinese) 43, 955 (1998).

Zeng, Z.

C. Jiang, Z. Zeng, and Q. Zhang, Hygiene Fascicule of Overseas Physic (in Chinese) 26, 147 (1999).

Zhang, Q.

C. Jiang, Z. Zeng, and Q. Zhang, Hygiene Fascicule of Overseas Physic (in Chinese) 26, 147 (1999).

Zhang, Z.

H. Zhao, Y. Yu, and Z. Zhang, Chin. Science Bulletin (in Chinese) 43, 955 (1998).

Zhao, H.

H. Zhao, Y. Yu, and Z. Zhang, Chin. Science Bulletin (in Chinese) 43, 955 (1998).

Zhou, D.

D. Zhou and W. Ke, Spectroscopy and Spectral Analysis 24, 1370 (2004).

Chin. J. Public Health (in Chinese)

J. Li, Y. Liu, W. Sun, and M. Cheng, Chin. J. Public Health (in Chinese) 22, 177 (2004).

Chin. Science Bulletin (in Chinese)

H. Zhao, Y. Yu, and Z. Zhang, Chin. Science Bulletin (in Chinese) 43, 955 (1998).

Eur. J. Nutr.

P. Moller, M. Viscovich, J. Lykkesfeldt, S. Loft, A. Jensen, and H. E. Polusen, Eur. J. Nutr. 43, 1 (2004).

Hygiene Fascicule of Overseas Physic (in Chinese)

C. Jiang, Z. Zeng, and Q. Zhang, Hygiene Fascicule of Overseas Physic (in Chinese) 26, 147 (1999).

F. Yu, Hygiene Fascicule of Overseas Physic (in Chinese) 29, 141 (2002).

Spectrochimica Acta Part A

W. Ke, D. Yu, and J. Wu, Spectrochimica Acta Part A 55, 1081 (1999).

Spectroscopy and Spectral Analysis

D. Zhou and W. Ke, Spectroscopy and Spectral Analysis 24, 1370 (2004).

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