Abstract

A compact line scanning quasi-confocal ophthalmoscope (LSO) is presented in this letter. Compared with a conventional scanning laser ophthalmoscope (SLO), the bench-top LSO significantly reduces the size, complexity, and cost of SLO utility with routine use. The LSO uses one moving part to produce high-contrast and high-resolution quasi-confocal images with nearly the same performance as a SLO. The LSO has a moderate field of view (~10°), which enables images of the macula, the optic nerve head, and other targets to be obtained more quickly and efficiently. An image of the optic nerve head is taken in a preliminary investigation on human subjects. Individual nerve fiber bundles and vessels are resolved at a shallow depth, with a lateral resolution of nearly 10 μm.

© 2013 Chinese Optics Letters

PDF Article

References

  • View by:
  • |
  • |
  • |

  1. R. H. Webb and G. W. Hughes, IEEE Trans. Biomed. Eng. BME-28, 488 (1981).
  2. R. H. Webb, G. W. Hughes, and F. C. Delori, Appl. Opt. 26, 1492 (1987).
  3. R. H. Webb and D. P. Wornson, "Scanning optical apparatus and method" U. S. Patent 4,768,874 (1988).
  4. A. E. Elsner, A. E. Jalkh, and J. J. Weiter, in Proceedings of Practical Atlas of Retinal Disease and Therapy 19 (1993).
  5. A. E. Elsner, L. Moraes, E. Beausencourt, A. Remky, S. A. Burns, J. J. Weiter, J. P. Walker, G. L. Wing, P. A. Raskauskas, and L. M. Kelley, Opt. Express 6, 243(2000).
  6. Y. S. Sabharwal, A. R. Rouse, L. Donaldson, M. F. Hopkins, and A. F. Gmitro, Appl. Opt. 38, 7133 (1999).
  7. C. J. R. Sheppard and X. Q. Mao, J. Mod. Opt. 25, 1169 (1998).
  8. T. R. Corle, C. H. Chou, and G. S. Kino, Opt. Lett. 11, 770 (1986).
  9. R. D. Ferguson, "Line-scan laser ophthalmoscope" U. S. Patent 6,758,564 (2004).
  10. D. X. Hammer, R. D. Ferguson, T. E. Ustun, C. E. Bigelow, N. V. Iftimia, and R. H. Webb, J. Biomed. Opt. 11, 041126 (2006).
  11. K.-B. Im, S. Han, H. Park, D. Kim, and B.-M. Kim, Opt. Express 13, 5151 (2005).
  12. Y. He, G. Shi, J. Lu, H. Li, and Y. Zhang, Acta Opt. Sin. (in Chinese) 32, 0117001 (2012).
  13. A. N. S. I. (ANSI), American National Standard for the Safe Use of Laser 2000, American National Standard Institute, Inc.

2012 (1)

Y. He, G. Shi, J. Lu, H. Li, and Y. Zhang, Acta Opt. Sin. (in Chinese) 32, 0117001 (2012).

2006 (1)

D. X. Hammer, R. D. Ferguson, T. E. Ustun, C. E. Bigelow, N. V. Iftimia, and R. H. Webb, J. Biomed. Opt. 11, 041126 (2006).

2005 (1)

2000 (1)

1999 (1)

1998 (1)

C. J. R. Sheppard and X. Q. Mao, J. Mod. Opt. 25, 1169 (1998).

1987 (1)

1986 (1)

1981 (1)

R. H. Webb and G. W. Hughes, IEEE Trans. Biomed. Eng. BME-28, 488 (1981).

Beausencourt, E.

Bigelow, C. E.

D. X. Hammer, R. D. Ferguson, T. E. Ustun, C. E. Bigelow, N. V. Iftimia, and R. H. Webb, J. Biomed. Opt. 11, 041126 (2006).

Burns, S. A.

Chou, C. H.

Corle, T. R.

Delori, F. C.

Donaldson, L.

Elsner, A. E.

Ferguson, R. D.

D. X. Hammer, R. D. Ferguson, T. E. Ustun, C. E. Bigelow, N. V. Iftimia, and R. H. Webb, J. Biomed. Opt. 11, 041126 (2006).

Gmitro, A. F.

Hammer, D. X.

D. X. Hammer, R. D. Ferguson, T. E. Ustun, C. E. Bigelow, N. V. Iftimia, and R. H. Webb, J. Biomed. Opt. 11, 041126 (2006).

Han, S.

He, Y.

Y. He, G. Shi, J. Lu, H. Li, and Y. Zhang, Acta Opt. Sin. (in Chinese) 32, 0117001 (2012).

Hopkins, M. F.

Hughes, G. W.

R. H. Webb, G. W. Hughes, and F. C. Delori, Appl. Opt. 26, 1492 (1987).

R. H. Webb and G. W. Hughes, IEEE Trans. Biomed. Eng. BME-28, 488 (1981).

Iftimia, N. V.

D. X. Hammer, R. D. Ferguson, T. E. Ustun, C. E. Bigelow, N. V. Iftimia, and R. H. Webb, J. Biomed. Opt. 11, 041126 (2006).

Im, K.-B.

Kelley, L. M.

Kim, B.-M.

Kim, D.

Kino, G. S.

Li, H.

Y. He, G. Shi, J. Lu, H. Li, and Y. Zhang, Acta Opt. Sin. (in Chinese) 32, 0117001 (2012).

Lu, J.

Y. He, G. Shi, J. Lu, H. Li, and Y. Zhang, Acta Opt. Sin. (in Chinese) 32, 0117001 (2012).

Mao, X. Q.

C. J. R. Sheppard and X. Q. Mao, J. Mod. Opt. 25, 1169 (1998).

Moraes, L.

Park, H.

Raskauskas, P. A.

Remky, A.

Rouse, A. R.

Sabharwal, Y. S.

Sheppard, C. J. R.

C. J. R. Sheppard and X. Q. Mao, J. Mod. Opt. 25, 1169 (1998).

Shi, G.

Y. He, G. Shi, J. Lu, H. Li, and Y. Zhang, Acta Opt. Sin. (in Chinese) 32, 0117001 (2012).

Ustun, T. E.

D. X. Hammer, R. D. Ferguson, T. E. Ustun, C. E. Bigelow, N. V. Iftimia, and R. H. Webb, J. Biomed. Opt. 11, 041126 (2006).

Walker, J. P.

Webb, R. H.

D. X. Hammer, R. D. Ferguson, T. E. Ustun, C. E. Bigelow, N. V. Iftimia, and R. H. Webb, J. Biomed. Opt. 11, 041126 (2006).

R. H. Webb, G. W. Hughes, and F. C. Delori, Appl. Opt. 26, 1492 (1987).

R. H. Webb and G. W. Hughes, IEEE Trans. Biomed. Eng. BME-28, 488 (1981).

Weiter, J. J.

Wing, G. L.

Zhang, Y.

Y. He, G. Shi, J. Lu, H. Li, and Y. Zhang, Acta Opt. Sin. (in Chinese) 32, 0117001 (2012).

Acta Opt. Sin. (in Chinese) (1)

Y. He, G. Shi, J. Lu, H. Li, and Y. Zhang, Acta Opt. Sin. (in Chinese) 32, 0117001 (2012).

Appl. Opt. (2)

IEEE Trans. Biomed. Eng. (1)

R. H. Webb and G. W. Hughes, IEEE Trans. Biomed. Eng. BME-28, 488 (1981).

J. Biomed. Opt. (1)

D. X. Hammer, R. D. Ferguson, T. E. Ustun, C. E. Bigelow, N. V. Iftimia, and R. H. Webb, J. Biomed. Opt. 11, 041126 (2006).

J. Mod. Opt. (1)

C. J. R. Sheppard and X. Q. Mao, J. Mod. Opt. 25, 1169 (1998).

Opt. Express (2)

Opt. Lett. (1)

Other (4)

A. N. S. I. (ANSI), American National Standard for the Safe Use of Laser 2000, American National Standard Institute, Inc.

R. D. Ferguson, "Line-scan laser ophthalmoscope" U. S. Patent 6,758,564 (2004).

R. H. Webb and D. P. Wornson, "Scanning optical apparatus and method" U. S. Patent 4,768,874 (1988).

A. E. Elsner, A. E. Jalkh, and J. J. Weiter, in Proceedings of Practical Atlas of Retinal Disease and Therapy 19 (1993).

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.