Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group
  • Chinese Optics Letters
  • Vol. 11,
  • Issue 1,
  • pp. 011703-
  • (2013)

Recent advances in two-photon imaging: technology developments and biomedical applications

Not Accessible

Your library or personal account may give you access

Abstract

In the past two decades, two-photon microscopy (TPM) transforms biomedical research, allowing nondestructive high-resolution fluorescent molecular imaging and label-free imaging in vivo and in real time. Here we review the recent advances of TPM technology including novel laser sources, new image acquisition paradigms, and microendoscopic imaging systems. Then, we survey the capabilities of TPM imaging of biological relevant molecules such as nicotinamide adenine dinucleotide (NADH), flavin adenine dinucleotide (FAD), and reactive oxygen species (ROS). Biomedical applications of TPM in neuroscience and cancer detection are demonstrated.

© 2013 Chinese Optics Letters

PDF Article
More Like This
Two-photon microendoscope for label-free imaging in stereotactic neurosurgery

Tarah A. Welton, Nicholas M. George, Baris N. Ozbay, Arianna Gentile Polese, Gregory Osborne, Gregory L. Futia, J. Keenan Kushner, Bette Kleinschmidt-DeMasters, Allyson L. Alexander, Aviva Abosch, Steven Ojemann, Diego Restrepo, and Emily A. Gibson
Biomed. Opt. Express 14(7) 3705-3725 (2023)

Information entropy of quantitative chemometric endogenous fluorescence improves photonic lung cancer diagnosis

Zhang Xu, Xin Xie, Run Li, Kangyuan Yu, Samantha R. Lish, and Min Xu
Appl. Opt. 61(2) 478-484 (2022)

Recent advances in organic optoelectronic devices for biomedical applications

Zhiyuan Chen, Sofian N. Obaid, and Luyao Lu
Opt. Mater. Express 9(9) 3843-3856 (2019)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved