Abstract

The sensitivity of diffuse optical tomography (DOT) imaging exponentially decreases with the increase of photon penetration depth, which leads to a poor depth resolution for DOT. In this letter, an exponential adjustment method (EAM) based on maximum singular value of layered sensitivity is proposed. Optimal depth resolution can be achieved by compensating the reduced sensitivity in the deep medium. Simulations are performed using a semi-infinite model and the simulation results show that the EAM method can substantially improve the depth resolution of deeply embedded objects in the medium. Consequently, the image quality and the reconstruction accuracy for these objects have been largely improved.

© 2008 Chinese Optics Letters

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2008 (2)

H. Niu, P. Guo, L. Ji, Q. Zhao, and T. Jiang, Opt. Express 16, 12423 (2008).

H.-J. Niu, P. Guo, and T.-Z. Jiang, Lecture Notes in Computer Science 5226, 514 (2008).

2007 (2)

2006 (1)

Q. Zhao, L. Ji, and T. Jiang, J. Biomed. Opt. 11, 064019 (2006).

2005 (1)

2004 (1)

2003 (1)

1999 (1)

1995 (2)

R. L. Barbour, H. L. Graber, J. Chang, S.-L. S. Barbour, P. C. Koo, and R. Aronson, IEEE Comput. Sci. Eng. 2, 63 (1995).

K. D. Paulsen and H. Jiang, Med. Phys. 22, 691 (1995).

1993 (1)

P. C. Hansen and D. P. O'Leary, SIAM J. Sci. Comput. 14, 1487 (1993).

1988 (1)

D. T. Delpy, M. Cope, P. van der Zee, S. Arridge, S. Wray, and J. Wyatt, Phys. Med. Biol. 33, 1433 (1988).

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R. L. Barbour, H. L. Graber, J. Chang, S.-L. S. Barbour, P. C. Koo, and R. Aronson, IEEE Comput. Sci. Eng. 2, 63 (1995).

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H. Niu, P. Guo, L. Ji, Q. Zhao, and T. Jiang, Opt. Express 16, 12423 (2008).

H.-J. Niu, P. Guo, and T.-Z. Jiang, Lecture Notes in Computer Science 5226, 514 (2008).

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P. C. Hansen and D. P. O'Leary, SIAM J. Sci. Comput. 14, 1487 (1993).

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Jiang, T.

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H.-J. Niu, P. Guo, and T.-Z. Jiang, Lecture Notes in Computer Science 5226, 514 (2008).

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Appl. Opt. (3)

Chin. Opt. Lett. (1)

IEEE Comput. Sci. Eng. (1)

R. L. Barbour, H. L. Graber, J. Chang, S.-L. S. Barbour, P. C. Koo, and R. Aronson, IEEE Comput. Sci. Eng. 2, 63 (1995).

J. Biomed. Opt. (1)

Q. Zhao, L. Ji, and T. Jiang, J. Biomed. Opt. 11, 064019 (2006).

Lecture Notes in Computer Science (1)

H.-J. Niu, P. Guo, and T.-Z. Jiang, Lecture Notes in Computer Science 5226, 514 (2008).

Med. Phys. (1)

K. D. Paulsen and H. Jiang, Med. Phys. 22, 691 (1995).

Opt. Express (2)

Opt. Lett. (1)

Phys. Med. Biol. (1)

D. T. Delpy, M. Cope, P. van der Zee, S. Arridge, S. Wray, and J. Wyatt, Phys. Med. Biol. 33, 1433 (1988).

SIAM J. Sci. Comput. (1)

P. C. Hansen and D. P. O'Leary, SIAM J. Sci. Comput. 14, 1487 (1993).

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