Abstract

Photoacoustic (PA) tomography (PAT) breaks the barrier for high-resolution optical imaging in a strong light-scattering medium, having a great potential for both clinical implementation and small animal studies. However, many organs and tissues lack enough PA contrast or even hinder the propagation of PA waves. Therefore, it is challenging to interpret pure PAT images, especially three-dimensional (3D) PA images for deep tissues, without enough structural information. To overcome this limitation, in this study, we integrated PAT with X-ray computed tomography (CT) in a standalone system. PAT provides optical contrast and CT gives anatomical information. We performed agar, tissue phantom, and animal studies, and the results demonstrated that PAT/CT imaging systems can provide accurate spatial registration of important complementary contrasts.

© 2018 Chinese Laser Press

Switchable preamplifier for dual modal photoacoustic and ultrasound imaging

Jinhee Yoo, Donghyeon Oh, Chulhong Kim, Hyung Ham Kim, and Ji-Yong Um
Biomed. Opt. Express 14(1) 89-105 (2023)

Combined diffuse optical tomography and photoacoustic tomography for enhanced functional imaging of small animals: a methodological study on phantoms

Yihan Wang, Jiao Li, Tong Lu, Limin Zhang, Zhongxing Zhou, Huijuan Zhao, and Feng Gao
Appl. Opt. 56(2) 303-311 (2017)

Assessment of microvasculature flow state with a high speed all-optic dual-modal system of optical coherence tomography and photoacoustic imaging

Zhenhe Ma, Shuzhuo Luo, Menghan Yu, Jian Liu, Yuqian Zhao, Yao Yu, Jiangtao Lv, Xiaofang Zhang, and Yi Wang
Biomed. Opt. Express 9(12) 6103-6115 (2018)

Photoacoustic and hyperspectral dual-modality endoscope

Ning Liu, Sihua Yang, and Da Xing
Opt. Lett. 43(1) 138-141 (2018)

High-resolution dual-modality photoacoustic ocular imaging

Ning Wu, Shuoqi Ye, Qiushi Ren, and Changhui Li
Opt. Lett. 39(8) 2451-2454 (2014)