In vivo fluorescence imaging of hepatocellular carcinoma xenograft using near-infrared labeled epidermal growth factor receptor (EGFR) peptide

Z. Li, Q. Zhou, J. Zhou, X. Duan, J. Zhu, and T. D. Wang

Biomed. Opt. Express 7(9), 3163-3169 (2016)  View: HTML | PDF  [Suppl. Mat. (3)]

Supercontinuum as a light source for miniaturized endoscopes

M. K. Lu, H. Y. Lin, C. C. Hsieh, and F. J. Kao

Biomed. Opt. Express 7(9), 3335-3344 (2016)  View: HTML | PDF

Handheld nonlinear microscope system comprising a 2 MHz repetition rate, mode-locked Yb-fiber laser for in vivo biomedical imaging

Ádám Krolopp, Attila Csákányi, Dóra Haluszka, Dániel Csáti, Lajos Vass, Attila Kolonics, Norbert Wikonkál, and Róbert Szipőcs

Biomed. Opt. Express 7(9), 3531-3542 (2016)  View: HTML | PDF

Procedures for risk-stratification of lung cancer using buccal nanocytology

H. Subramanian, P. Viswanathan, L. Cherkezyan, R. Iyengar, S. Rozhok, M. Verleye, J. Derbas, J. Czarnecki, H. K. Roy, and V. Backman

Biomed. Opt. Express 7(9), 3795-3810 (2016)  View: HTML | PDF

Optical coherence tomography endoscopic probe based on a tilted MEMS mirror

Can Duan, Quentin Tanguy, Antonio Pozzi, and Huikai Xie

Biomed. Opt. Express 7(9), 3345-3354 (2016)  View: HTML | PDF

Visible-light optical coherence tomography-based multimodal retinal imaging for improvement of fluorescent intensity quantification

Zahra Nafar, Minshan Jiang, Rong Wen, and Shuliang Jiao

Biomed. Opt. Express 7(9), 3220-3229 (2016)  View: HTML | PDF

Multi-spectral photoacoustic elasticity tomography

Yubin Liu and Zhen Yuan

Biomed. Opt. Express 7(9), 3323-3334 (2016)  View: HTML | PDF

Non-invasive diffuse correlation tomography reveals spatial and temporal blood flow differences in murine bone grafting approaches

Songfeng Han, Ashley R. Proctor, Joseph B. Vella, Danielle S. W. Benoit, and Regine Choe

Biomed. Opt. Express 7(9), 3262-3279 (2016)  View: HTML | PDF

Chemotherapeutic drug-specific alteration of microvascular blood flow in murine breast cancer as measured by diffuse correlation spectroscopy

Gabriel Ramirez, Ashley R. Proctor, Ki Won Jung, Tong Tong Wu, Songfeng Han, Russell R. Adams, Jingxuan Ren, Daniel K. Byun, Kelley S. Madden, Edward B. Brown, Thomas H. Foster, Parisa Farzam, Turgut Durduran, and Regine Choe

Biomed. Opt. Express 7(9), 3610-3630 (2016)  View: HTML | PDF

Time resolved diffuse optical spectroscopy with geometrically accurate models for bulk parameter recovery

James A. Guggenheim, Ilaria Bargigia, Andrea Farina, Antonio Pifferi, and Hamid Dehghani

Biomed. Opt. Express 7(9), 3784-3794 (2016)  View: HTML | PDF

Unconstrained pulse pressure monitoring for health management using hetero-core fiber optic sensor

Michiko Nishiyama, Masako Sonobe, and Kazuhiro Watanabe

Biomed. Opt. Express 7(9), 3675-3685 (2016)  View: HTML | PDF

Photonic sensing of arterial distension

Dominic Ruh, Sivaraman Subramanian, Stanislav Sherman, Johannes Ruhhammer, Michael Theodor, Lebrecht Dirk, Katharina Foerster, Claudia Heilmann, Friedhelm Beyersdorf, Hans Zappe, and Andreas Seifert

Biomed. Opt. Express 7(9), 3230-3246 (2016)  View: HTML | PDF

Multi-parameter analysis using photovoltaic cell-based optofluidic cytometer

Chien-Shun Yan and Yao-Nan Wang

Biomed. Opt. Express 7(9), 3585-3595 (2016)  View: HTML | PDF

Optofluidic chips with nanochannels for dynamic molecular detection using enhanced fluorescence

P. A. Postigo, R. Alvaro, A. Juarros, and S. Merino

Biomed. Opt. Express 7(9), 3289-3298 (2016)  View: HTML | PDF

Dark field optical imaging reveals vascular changes in an inducible hamster cheek pouch model during carcinogenesis

Fangyao Hu, Robert Morhard, Helen A. Murphy, Caigang Zhu, and Nimmi Ramanujam

Biomed. Opt. Express 7(9), 3247-3261 (2016)  View: HTML | PDF

Microdose fluorescence imaging of ABY-029 on an operating microscope adapted by custom illumination and imaging modules

Jonathan T. Elliott, Alisha V. Dsouza, Kayla Marra, Brian W. Pogue, David W. Roberts, and Keith D. Paulsen

Biomed. Opt. Express 7(9), 3280-3288 (2016)  View: HTML | PDF

Tracking single fluorescent particles in three dimensions via extremum seeking

Trevor T. Ashley, Eric L. Gan, Jane Pan, and Sean B. Andersson

Biomed. Opt. Express 7(9), 3355-3376 (2016)  View: HTML | PDF

Dual-modality endomicroscopy with co-registered fluorescence and phase contrast

C. Ba, M. Palmiere, J. Ritt, and J. Mertz

Biomed. Opt. Express 7(9), 3403-3411 (2016)  View: HTML | PDF  [Suppl. Mat. (2)]

Algorithms for differentiating between images of heterogeneous tissue across fluorescence microscopes

Rhea Chitalia, Jenna Mueller, Henry L. Fu, Melodi Javid Whitley, David G. Kirsch, J. Quincy Brown, Rebecca Willett, and Nimmi Ramanujam

Biomed. Opt. Express 7(9), 3412-3424 (2016)  View: HTML | PDF

Design of a fiber-optic multiphoton microscopy handheld probe

Yuan Zhao, Mingyu Sheng, Lin Huang, and Shuo Tang

Biomed. Opt. Express 7(9), 3425-3437 (2016)  View: HTML | PDF

Multiphoton excited hemoglobin fluorescence and third harmonic generation for non-invasive microscopy of stored blood

Ilyas Saytashev, Rachel Glenn, Gabrielle A. Murashova, Sam Osseiran, Dana Spence, Conor L. Evans, and Marcos Dantus

Biomed. Opt. Express 7(9), 3449-3460 (2016)  View: HTML | PDF  [Suppl. Mat. (2)]

Automated, highly reproducible, wide-field, light-based cortical mapping method using a commercial stereo microscope and its applications

Su Jiang, Ya-Feng Liu, Xiao-Min Wang, Ke-Fei Liu, Ding-Hong Zhang, Yi-Ding Li, Ai-Ping Yu, Xiao-Hui Zhang, Jia-Yi Zhang, Jian-Guang Xu, Yu-Dong Gu, Wen-Dong Xu, and Shao-Qun Zeng

Biomed. Opt. Express 7(9), 3478-3490 (2016)  View: HTML | PDF

Characterizing fibrosis in UUO mice model using multiparametric analysis of phasor distribution from FLIM images

Suman Ranjit, Alexander Dvornikov, Moshe Levi, Seth Furgeson, and Enrico Gratton

Biomed. Opt. Express 7(9), 3519-3530 (2016)  View: HTML | PDF

High-resolution real-time dual-view imaging with multiple point of view microscopy

Pierre Mangeol and Erwin J. G. Peterman

Biomed. Opt. Express 7(9), 3631-3642 (2016)  View: HTML | PDF  [Suppl. Mat. (4)]

Motion quantification during multi-photon functional imaging in behaving animals

Lingjie Kong, Justin P. Little, and Meng Cui

Biomed. Opt. Express 7(9), 3686-3695 (2016)  View: HTML | PDF  [Suppl. Mat. (2)]

3D imaging in CUBIC-cleared mouse heart tissue: going deeper

Imke Nehrhoff, Diana Bocancea, Javier Vaquero, Juan José Vaquero, Jorge Ripoll, Manuel Desco, and María Victoria Gómez-Gaviro

Biomed. Opt. Express 7(9), 3716-3720 (2016)  View: HTML | PDF  [Suppl. Mat. (4)]

Imaging in turbid media: a transmission detector gives 2-3 order of magnitude enhanced sensitivity compared to epi-detection schemes

Alexander Dvornikov and Enrico Gratton

Biomed. Opt. Express 7(9), 3747-3755 (2016)  View: HTML | PDF

Combined multi-modal photoacoustic tomography, optical coherence tomography (OCT) and OCT angiography system with an articulated probe for in vivo human skin structure and vasculature imaging

Mengyang Liu, Zhe Chen, Behrooz Zabihian, Christoph Sinz, Edward Zhang, Paul C. Beard, Laurin Ginner, Erich Hoover, Micheal P. Minneman, Rainer A. Leitgeb, Harald Kittler, and Wolfgang Drexler

Biomed. Opt. Express 7(9), 3390-3402 (2016)  View: HTML | PDF  [Suppl. Mat. (2)]

Direct visualization of functional heterogeneity in hepatobiliary metabolism using 6-CFDA as model compound

Chih-Ju Lin, Feng-Chieh Li, Yu-Yang Lee, Te-Yu Tseng, Wei-Liang Chen, Vladimir Hovhannisyan, Ning Kang, Nicholas G. Horton, Shu-Jen Chiang, Chris Xu, Hsuan-Shu Lee, and Chen-Yuan Dong

Biomed. Opt. Express 7(9), 3574-3584 (2016)  View: HTML | PDF  [Suppl. Mat. (1)]

Visualization of prostatic nerves by polarization-sensitive optical coherence tomography

Yeoreum Yoon, Seung Hwan Jeon, Yong Hyun Park, Won Hyuk Jang, Ji Youl Lee, and Ki Hean Kim

Biomed. Opt. Express 7(9), 3170-3183 (2016)  View: HTML | PDF  [Suppl. Mat. (10)]

Multimodal optical coherence tomography and fluorescence lifetime imaging with interleaved excitation sources for simultaneous endogenous and exogenous fluorescence

Sebina Shrestha, Michael J. Serafino, Jesus Rico-Jimenez, Jesung Park, Xi Chen, Siqin Zhaorigetu, Brian L. Walton, Javier A. Jo, and Brian E. Applegate

Biomed. Opt. Express 7(9), 3184-3197 (2016)  View: HTML | PDF

Imaging hemodynamic response after ischemic stroke in mouse cortex using visible-light optical coherence tomography

Siyu Chen, Qi Liu, Xiao Shu, Brian Soetikno, Shanbao Tong, and Hao F. Zhang

Biomed. Opt. Express 7(9), 3377-3389 (2016)  View: HTML | PDF

Measurement of biofilm growth and local hydrodynamics using optical coherence tomography

Nicolás Weiss, Khalid El Tayeb El Obied, Jeroen Kalkman, Rob G.H. Lammertink, and Ton G. van Leeuwen

Biomed. Opt. Express 7(9), 3508-3518 (2016)  View: HTML | PDF

Estimation of Jones matrix, birefringence and entropy using Cloude-Pottier decomposition in polarization-sensitive optical coherence tomography

Masahiro Yamanari, Satoru Tsuda, Taiki Kokubun, Yukihiro Shiga, Kazuko Omodaka, Naoko Aizawa, Yu Yokoyama, Noriko Himori, Shiho Kunimatsu-Sanuki, Kazuichi Maruyama, Hiroshi Kunikata, and Toru Nakazawa

Biomed. Opt. Express 7(9), 3551-3573 (2016)  View: HTML | PDF

Classification of basal cell carcinoma in human skin using machine learning and quantitative features captured by polarization sensitive optical coherence tomography

Tahereh Marvdashti, Lian Duan, Sumaira Z. Aasi, Jean Y. Tang, and Audrey K. Ellerbee Bowden

Biomed. Opt. Express 7(9), 3721-3735 (2016)  View: HTML | PDF

Single cell ionization by a laser trap: a preliminary study in measuring radiation dose and charge in BT20 breast carcinoma cells

Michele Kelley, Ying Gao, and Daniel Erenso

Biomed. Opt. Express 7(9), 3438-3448 (2016)  View: HTML | PDF

Whole-body multispectral photoacoustic imaging of adult zebrafish

Na Huang, Heng Guo, Weizhi Qi, Zhiwei Zhang, Jian Rong, Zhen Yuan, Wei Ge, Huabei Jiang, and Lei Xi

Biomed. Opt. Express 7(9), 3543-3550 (2016)  View: HTML | PDF  [Suppl. Mat. (1)]

Preclinical photoacoustic models: application for ultrasensitive single cell malaria diagnosis in large vein and artery

Yulian A. Menyaev, Kai A. Carey, Dmitry A. Nedosekin, Mustafa Sarimollaoglu, Ekaterina I. Galanzha, Jason S. Stumhofer, and Vladimir P. Zharov

Biomed. Opt. Express 7(9), 3643-3658 (2016)  View: HTML | PDF

Pencil beam all-optical ultrasound imaging

Erwin J. Alles, Sacha Noimark, Edward Zhang, Paul C. Beard, and Adrien E. Desjardins

Biomed. Opt. Express 7(9), 3696-3704 (2016)  View: HTML | PDF  [Suppl. Mat. (4)]

In vitro neuronal depolarization and increased synaptic activity induced by infrared neural stimulation

Blake Entwisle, Simon McMullan, Phillip Bokiniec, Simon Gross, Roger Chung, and Michael Withford

Biomed. Opt. Express 7(9), 3211-3219 (2016)  View: HTML | PDF

Full-field interferometry for counting and differentiating aquatic biotic nanoparticles: from laboratory to Tara Oceans

Martine Boccara, Yasmina Fedala, Catherine Venien Bryan, Marc Bailly-Bechet, Chris Bowler, and Albert Claude Boccara

Biomed. Opt. Express 7(9), 3736-3746 (2016)  View: HTML | PDF

Terahertz transmission vs reflection imaging and model-based characterization for excised breast carcinomas

Tyler Bowman, Magda El-Shenawee, and Lucas K. Campbell

Biomed. Opt. Express 7(9), 3756-3783 (2016)  View: HTML | PDF

Continuous cerebral hemodynamic measurement during deep hypothermic circulatory arrest

David R. Busch, Craig G. Rusin, Wanda Miller-Hance, Kathy Kibler, Wesley B. Baker, Jeffrey S. Heinle, Charles D. Fraser, Arjun G. Yodh, Daniel J. Licht, and Kenneth M. Brady

Biomed. Opt. Express 7(9), 3461-3470 (2016)  View: HTML | PDF

Bundled-optode implementation for 3D imaging in functional near-infrared spectroscopy

Hoang-Dung Nguyen and Keum-Shik Hong

Biomed. Opt. Express 7(9), 3491-3507 (2016)  View: HTML | PDF

Imaging brain activity during seizures in freely behaving rats using a miniature multi-modal imaging system

Iliya Sigal, Margaret M. Koletar, Dene Ringuette, Raanan Gad, Melanie Jeffrey, Peter L. Carlen, Bojana Stefanovic, and Ofer Levi

Biomed. Opt. Express 7(9), 3596-3609 (2016)  View: HTML | PDF  [Suppl. Mat. (2)]

Assessment of a multi-layered diffuse correlation spectroscopy method for monitoring cerebral blood flow in adults

Kyle Verdecchia, Mamadou Diop, Albert Lee, Laura B. Morrison, Ting-Yim Lee, and Keith St. Lawrence

Biomed. Opt. Express 7(9), 3659-3674 (2016)  View: HTML | PDF

Real-time in vivo diagnosis of laryngeal carcinoma with rapid fiber-optic Raman spectroscopy

Kan Lin, Wei Zheng, Chwee Ming Lim, and Zhiwei Huang

Biomed. Opt. Express 7(9), 3705-3715 (2016)  View: HTML | PDF

Combination of confocal principle and aperture stop separation improves suppression of crystalline lens fluorescence in an eye model

Matthias Klemm, Johannes Blum, Dietmar Link, Martin Hammer, Jens Haueisen, and Dietrich Schweitzer

Biomed. Opt. Express 7(9), 3198-3210 (2016)  View: HTML | PDF

Minimum change in spherical aberration that can be perceived

Silvestre Manzanera and Pablo Artal

Biomed. Opt. Express 7(9), 3471-3477 (2016)  View: HTML | PDF  [Suppl. Mat. (1)]

Structure-adaptive CBCT reconstruction using weighted total variation and Hessian penalties

Qi Shi, Nanbo Sun, Tao Sun, Jing Wang, and Shan Tan

Biomed. Opt. Express 7(9), 3299-3322 (2016)  View: HTML | PDF