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1 July 2021, Volume 12, Issue 7, pp. 3743-4626  
59 articles

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Isolating individual polarization effects from the Mueller matrix: comparison of two non-decomposition techniques

Muaz Iqbal, Banat Gul, Shamim Khan, Sumara Ashraf, and Iftikhar Ahmad

Biomed. Opt. Express 12(7), 3743-3759 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Quantitative structural imaging of keratoconic corneas using polarization-resolved SHG microscopy

Clothilde Raoux, Margaux Schmeltz, Marion Bied, Maged Alnawaiseh, Uwe Hansen, Gaël Latour, and Marie-Claire Schanne-Klein

Biomed. Opt. Express 12(7), 4163-4178 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Polarization properties of retinal blood vessel walls measured with polarization sensitive optical coherence tomography

Hadi Afsharan, Michael J. Hackmann, Qiang Wang, Farzaneh Navaeipour, Stephy Vijaya Kumar Jayasree, Robert J. Zawadzki, Dilusha Silva, Chulmin Joo, and Barry Cense

Biomed. Opt. Express 12(7), 4340-4362 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Composite polarization systems for independent controlling polarization of two beams with different wavelengths

Evelina A. Bibikova, Nataliya D. Kundikova, Yurii V. Mukhin, and Vladimir V. Chirkov

Biomed. Opt. Express 12(7), 4046-4055 (2021)  View: HTML | PDF

Backscattering polarimetric imaging of the human brain to determine the orientation and degree of alignment of nerve fiber bundles

Arushi Jain, Leonie Ulrich, Michael Jaeger, Philippe Schucht, Martin Frenz, and H. Günhan Akarcay

Biomed. Opt. Express 12(7), 4452-4466 (2021)  View: HTML | PDF  [Suppl. Mat. (4)]

Polarization and depolarization metrics as optical markers in support to histopathology of ex vivo colon tissue

Deyan Ivanov, Viktor Dremin, Ekaterina Borisova, Alexander Bykov, Tatiana Novikova, Igor Meglinski, and Razvigor Ossikovski

Biomed. Opt. Express 12(7), 4560-4572 (2021)  View: HTML | PDF

Probing layered structures by multi-color backscattering polarimetry and machine learning

Yuanhuan Zhu, Yang Dong, Yue Yao, Lu Si, Yudi Liu, Honghui He, and Hui Ma

Biomed. Opt. Express 12(7), 4324-4339 (2021)  View: HTML | PDF

Controlling the optical pathlength in continuous-wave reflectance spectroscopy using polarization

Callum M. Macdonald, Susmita Sridhar, Hung T. X. Do, Javier Luna-Labrador, Mouloud Adel, and Anabela Da Silva

Biomed. Opt. Express 12(7), 4401-4413 (2021)  View: HTML | PDF

Translational Photoacoustic Imaging for Disease Diagnosis, Monitoring, and Surgical Guidance: introduction to the feature issue

Jun Xia, Muyinatu A. Lediju Bell, Jan Laufer, and Junjie Yao

Biomed. Opt. Express 12(7), 4115-4118 (2021)  View: HTML | PDF

Automatic threshold selection algorithm to distinguish a tissue chromophore from the background in photoacoustic imaging

Azin Khodaverdi, Tobias Erlöv, Jenny Hult, Nina Reistad, Agnes Pekar-Lukacs, John Albinsson, Aboma Merdasa, Rafi Sheikh, Malin Malmsjö, and Magnus Cinthio

Biomed. Opt. Express 12(7), 3836-3850 (2021)  View: HTML | PDF

Photoacoustic imaging for the monitoring of local changes in oxygen saturation following an adrenaline injection in human forearm skin

Josefine Bunke, Aboma Merdasa, Rafi Sheikh, John Albinsson, Tobias Erlöv, Bodil Gesslein, Magnus Cinthio, Nina Reistad, and Malin Malmsjö

Biomed. Opt. Express 12(7), 4084-4096 (2021)  View: HTML | PDF

Comparison of photoacoustic imaging and histopathological examination in determining the dimensions of 52 human melanomas and nevi ex vivo

Jenny Hult, Aboma Merdasa, Agnes Pekar-Lukacs, Magne Tordengren Stridh, Azin Khodaverdi, John Albinsson, Bodil Gesslein, Ulf Dahlstrand, Linn Engqvist, Yousef Hamid, Douglas Larsson Albèr, Bertil Persson, Tobias Erlöv, Rafi Sheikh, Magnus Cinthio, and Malin Malmsjö

Biomed. Opt. Express 12(7), 4097-4114 (2021)  View: HTML | PDF

Photoacoustic computed tomography for functional human brain imaging [Invited]

Shuai Na and Lihong V. Wang

Biomed. Opt. Express 12(7), 4056-4083 (2021)  View: HTML | PDF

Depth-recognizable time-domain fluorescence molecular tomography in reflective geometry

Jiaju Cheng, Peng Zhang, Chuangjian Cai, Yang Gao, Jie Liu, Hui Hui, Jie Tian, and Jianwen Luo

Biomed. Opt. Express 12(7), 3806-3818 (2021)  View: HTML | PDF

Method of transmission filters to measure emission spectra in strongly scattering media

Belén Torrado, Alexander Dvornikov, and Enrico Gratton

Biomed. Opt. Express 12(7), 3760-3774 (2021)  View: HTML | PDF

Biochemical resolving power of fluorescence lifetime imaging: untangling the roles of the instrument response function and photon-statistics

Andrew L. Trinh and Alessandro Esposito

Biomed. Opt. Express 12(7), 3775-3788 (2021)  View: HTML | PDF

High-resolution light-field microscopy with patterned illumination

Depeng Wang, Suva Roy, Andra M. Rudzite, Greg D. Field, and Yiyang Gong

Biomed. Opt. Express 12(7), 3887-3901 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Real-time pixelwise phasor analysis for video-rate two-photon fluorescence lifetime imaging microscopy

Janet E. Sorrells, Rishyashring R. Iyer, Lingxiao Yang, Andrew J. Bower, Darold R. Spillman, Eric J. Chaney, Haohua Tu, and Stephen A. Boppart

Biomed. Opt. Express 12(7), 4003-4019 (2021)  View: HTML | PDF  [Suppl. Mat. (3)]

Combining quantitative phase microscopy and laser-induced shockwave for the study of cell injury

Pegah Pouladian, Toyohiko Yamauchi, Nicole M. Wakida, Veronica Gomez-Godinez, Michael W. Berns, and Daryl Preece

Biomed. Opt. Express 12(7), 4020-4031 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Quantitation of cerebral oxygen tension using phasor analysis and phosphorescence lifetime imaging microscopy (PLIM)

Chang Liu, Amanda Chisholm, Buyin Fu, Clover T.-Y. Su, İkbal Şencan, Sava Sakadžić, and Mohammad A. Yaseen

Biomed. Opt. Express 12(7), 4192-4206 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Common-path intrinsically achromatic optical diffraction tomography

Piotr Zdańkowski, Julianna Winnik, Krzysztof Patorski, Paweł Gocłowski, Michał Ziemczonok, Michał Józwik, Małgorzata Kujawińska, and Maciej Trusiak

Biomed. Opt. Express 12(7), 4219-4234 (2021)  View: HTML | PDF  [Suppl. Mat. (6)]

Histogram clustering for rapid time-domain fluorescence lifetime image analysis

Yahui Li, Natakorn Sapermsap, Jun Yu, Jinshou Tian, Yu Chen, and David Day-Uei Li

Biomed. Opt. Express 12(7), 4293-4307 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Organelle-specific phase contrast microscopy enables gentle monitoring and analysis of mitochondrial network dynamics

Siyue Guo, Ying Ma, Yang Pan, Zachary J. Smith, and Kaiqin Chu

Biomed. Opt. Express 12(7), 4363-4379 (2021)  View: HTML | PDF  [Suppl. Mat. (6)]

Self-contained and modular structured illumination microscope

Robin Van den Eynde, Wim Vandenberg, Siewert Hugelier, Arno Bouwens, Johan Hofkens, Marcel Müller, and Peter Dedecker

Biomed. Opt. Express 12(7), 4414-4422 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Iterative optical technique for detecting anti-leishmania nanoparticles in mouse lesions

Inbar Yariv, Sriram Kannan, Yifat Harel, Esthy Levy, Hamootal Duadi, Jean-Paul Lellouche, Shulamit Michaeli, and Dror Fixler

Biomed. Opt. Express 12(7), 4496-4509 (2021)  View: HTML | PDF

Effects of photobiomodulation on the redox state of healthy and cancer cells

Clara Maria Gonçalves de Faria, Heloisa Ciol, Vanderlei Salvador Bagnato, and Sebastião Pratavieira

Biomed. Opt. Express 12(7), 3902-3916 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Towards personalized and versatile monitoring of temperature fields within heterogeneous tissues during laser therapies

Jure Kosir, Daniele Vella, Matjaz Lukac, and Matija Jezersek

Biomed. Opt. Express 12(7), 4530-4543 (2021)  View: HTML | PDF

Space curvature-inspired nanoplasmonic sensor for breast cancer extracellular vesicle fingerprinting and machine learning classification

Mohammadrahim Kazemzadeh, Colin L. Hisey, Anastasiia Artuyants, Cherie Blenkiron, Lawrence W. Chamley, Kamran Zargar-Shoshtari, Weiliang Xu, and Neil G. R. Broderick

Biomed. Opt. Express 12(7), 3965-3981 (2021)  View: HTML | PDF

Editors' Pick

Multiplex optical biosensors based on multi-pinhole interferometry

Johannes Bläsi and Martina Gerken

Biomed. Opt. Express 12(7), 4265-4275 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Highly sensitive crumpled 2D material-based plasmonic biosensors

Vahid Faramarzi, Vahid Ahmadi, Michael T. Hwang, and Peter Snapp

Biomed. Opt. Express 12(7), 4544-4559 (2021)  View: HTML | PDF

Volumetric growth tracking of patient-derived cancer organoids using optical coherence tomography

Daniel A. Gil, Dustin A. Deming, and Melissa C. Skala

Biomed. Opt. Express 12(7), 3789-3805 (2021)  View: HTML | PDF

Computational multi-directional optical coherence tomography for visualizing the microstructural directionality of the tissue

Daisuke Oida, Kiriko Tomita, Kensuke Oikawa, Tai-Ang Wang, Shuichi Makita, Meng-Tsan Tsai, and Yoshiaki Yasuno

Biomed. Opt. Express 12(7), 3851-3864 (2021)  View: HTML | PDF

Full circumferential morphological analysis of Schlemm’s canal in human eyes using megahertz swept source OCT

Xinwen Yao, Bingyao Tan, Yijie Ho, Xinyu Liu, Damon Wong, Jacqueline Chua, Tina T. Wong, Shamira Perera, Marcus Ang, René M. Werkmeister, and Leopold Schmetterer

Biomed. Opt. Express 12(7), 3865-3877 (2021)  View: HTML | PDF  [Suppl. Mat. (4)]

Minimizing OCT quantification error via a surface-tracking imaging probe

Hyeon-Cheol Park, Ang Li, Honghua Guan, Chetan Bettegowda, Kaisorn Chaichana, Alfredo Quiñones-Hinojosa, and Xingde Li

Biomed. Opt. Express 12(7), 3992-4002 (2021)  View: HTML | PDF  [Suppl. Mat. (3)]

Developing a normative database for retinal perfusion using optical coherence tomography angiography

Bingyao Tan, Yin Ci Sim, Jacqueline Chua, Dheo Yusufi, Damon Wong, Ai Ping Yow, Calvin Chin, Anna C. S. Tan, Chelvin C. A. Sng, Rupesh Agrawal, Lekha Gopal, Ralene Sim, Gavin Tan, Ecosse Lamoureux, and Leopold Schmetterer

Biomed. Opt. Express 12(7), 4032-4045 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Speckle statistics of biological tissues in optical coherence tomography

Gary R. Ge, Jannick P. Rolland, and Kevin J. Parker

Biomed. Opt. Express 12(7), 4179-4191 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Editors' Pick

Dual-modality optical coherence tomography and fluorescence tethered capsule endomicroscopy

Andreas Wartak, Alfred K. Kelada, Paola A. Leon Alarcon, Ara L. Bablouzian, Osman O. Ahsen, Abigail L. Gregg, Yuxiao Wei, Keval Bollavaram, Conor J. Sheil, Edward Farewell, Schuyler VanTol, Rachel Smith, Patricia Grahmann, Aaron R. Baillargeon, Joseph A. Gardecki, and Guillermo J. Tearney

Biomed. Opt. Express 12(7), 4308-4323 (2021)  View: HTML | PDF

Identification and quantification of fibrotic areas in the human retina using polarization-sensitive OCT

Alice R. Motschi, Philipp K. Roberts, Sylvia Desissaire, Markus Schranz, Florian Schwarzhans, Hrvoje Bogunović, Michael Pircher, and Christoph K. Hitzenberger

Biomed. Opt. Express 12(7), 4380-4400 (2021)  View: HTML | PDF

Optical coherence microangiography of the mouse kidney for diagnosis of circulatory disorders

Arkady S. Abdurashitov, Ekaterina S. Prikhozhdenko, Oksana A. Mayorova, Valentina O. Plastun, Olga I. Gusliakova, Natalia A. Shushunova, Oleg A. Kulikov, Valery V. Tuchin, Gleb B. Sukhorukov, and Olga A. Sindeeva

Biomed. Opt. Express 12(7), 4467-4477 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Analysis of correlations between local geographic atrophy growth rates and local OCT angiography-measured choriocapillaris flow deficits

Eric M. Moult, Yingying Shi, Qinqin Zhang, Liang Wang, Rahul Mazumder, Siyu Chen, Zhongdi Chu, William Feuer, Nadia K. Waheed, Giovanni Gregori, Ruikang K. Wang, Philip J. Rosenfeld, and James G. Fujimoto

Biomed. Opt. Express 12(7), 4573-4595 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Robotic-arm-assisted flexible large field-of-view optical coherence tomography

Yong Huang, Xiaochen Li, Junyu Liu, Zhengyu Qiao, Jingsi Chen, and Qun Hao

Biomed. Opt. Express 12(7), 4596-4609 (2021)  View: HTML | PDF

Rapid, non-invasive measurement of gastric emptying rate using transcutaneous fluorescence spectroscopy

Aaron M. Lett, Alexandra Lim, Charlotte Skinner, James Maurice, Nikhil Vergis, Ara Darzi, Robert Goldin, Mark Thursz, and Alex J. Thompson

Biomed. Opt. Express 12(7), 4249-4264 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Simulations of fluorescence imaging in the oral cavity

Zheng Lyu, Haomiao Jiang, Feng Xiao, Jian Rong, Tingcheng Zhang, Brian Wandell, and Joyce Farrell

Biomed. Opt. Express 12(7), 4276-4292 (2021)  View: HTML | PDF

Predictive data clustering of laser-induced breakdown spectroscopy for brain tumor analysis

Geer Teng, Qianqian Wang, Xutai Cui, Guoyan Chen, Kai Wei, Xiangjun Xu, Bushra Sana Idrees, and M. Nouman Khan

Biomed. Opt. Express 12(7), 4438-4451 (2021)  View: HTML | PDF

Explainable liver tumor delineation in surgical specimens using hyperspectral imaging and deep learning

Yating Zhang, Si Yu, Xueyu Zhu, Xuefei Ning, Wei Liu, Chuting Wang, Xiaohu Liu, Ding Zhao, Yongchang Zheng, and Jie Bao

Biomed. Opt. Express 12(7), 4510-4529 (2021)  View: HTML | PDF

Photodynamic therapy reduces metastasis of breast cancer by minimizing circulating tumor cells

Xiaofu Weng, Dan Wei, Zhangru Yang, Wen Pang, Kai Pang, Bobo Gu, and Xunbin Wei

Biomed. Opt. Express 12(7), 3878-3886 (2021)  View: HTML | PDF

Endoscopic ultrasound (EUS)-guided cylindrical interstitial laser ablation (CILA) on in vivo porcine pancreas

Van Gia Truong, Seok Jeong, Jin-Seok Park, Van Nam Tran, Sung Min Kim, Don Haeng Lee, and Hyun Wook Kang

Biomed. Opt. Express 12(7), 4423-4437 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Plasmonic optical fiber for bacteria manipulation—characterization and visualization of accumulation behavior under plasmo-thermal trapping

Jang Ah Kim, Eric M. Yeatman, and Alex J. Thompson

Biomed. Opt. Express 12(7), 3917-3933 (2021)  View: HTML | PDF  [Suppl. Mat. (5)]

Towards in vivo photoacoustic imaging of vulnerable plaques in the carotid artery

Jan-Willem Muller, Roy van Hees, Marc van Sambeek, Pierre Boutouyrie, Marcel Rutten, Peter Brands, Min Wu, and Richard Lopata

Biomed. Opt. Express 12(7), 4207-4218 (2021)  View: HTML | PDF

Spectroscopy of excised skin patches exposed to THz and far-IR radiation

Alireza Lajevardipour, Zoltan Vilagosh, Dominique Appadoo, Jeffrey Davis, Saulius Juodkazis, and Andrew Wood

Biomed. Opt. Express 12(7), 4610-4626 (2021)  View: HTML | PDF

Editors' Pick

Evaluation of the changes in human milk lipid composition and conformational state with Raman spectroscopy during a breastfeed

Johanna R. de Wolf, Anki Lenferink, Aufried Lenferink, Cees Otto, and Nienke Bosschaart

Biomed. Opt. Express 12(7), 3934-3947 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Longitudinal monitoring of tumor response to immune checkpoint inhibitors using noninvasive diffuse reflectance spectroscopy

Joel Rodriguez Troncoso, Paola Monterroso Diaz, David E. Lee, Charles M. Quick, and Narasimhan Rajaram

Biomed. Opt. Express 12(7), 3982-3991 (2021)  View: HTML | PDF

Non-invasive transabdominal measurement of placental oxygenation: a step toward continuous monitoring

Thien Nguyen, Kosar Khaksari, Siddharth M. Khare, Soongho Park, Afrouz A. Anderson, Janine Bieda, Eunjung Jung, Chaur-Dong Hsu, Roberto Romero, and Amir H. Gandjbakhche

Biomed. Opt. Express 12(7), 4119-4130 (2021)  View: HTML | PDF

Quantification of blood flow index in diffuse correlation spectroscopy using long short-term memory architecture

Zhe Li, Qisi Ge, Jinchao Feng, Kebin Jia, and Jing Zhao

Biomed. Opt. Express 12(7), 4131-4146 (2021)  View: HTML | PDF

Hemodynamics of the sternocleidomastoid measured with frequency domain near-infrared spectroscopy towards non-invasive monitoring during mechanical ventilation

Raeef Istfan, Carlos A. Gómez, Matthew Applegate, Dmitry Rozenberg, W. Darlene Reid, and Darren Roblyer

Biomed. Opt. Express 12(7), 4147-4162 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Microvascular blood flow changes of the abductor pollicis brevis muscle during sustained static exercise

Martina Giovannella, Evelina Urtane, Marta Zanoletti, Umut Karadeniz, Uldis Rubins, Udo M. Weigel, Zbignevs Marcinkevics, and Turgut Durduran

Biomed. Opt. Express 12(7), 4235-4248 (2021)  View: HTML | PDF

Analytical optimization of the cutting efficiency for generic cavitation bubbles

Samuel Arba-Mosquera, Pascal Naubereit, Simas Sobutas, and Shwetabh Verma

Biomed. Opt. Express 12(7), 3819-3835 (2021)  View: HTML | PDF

Retinal contour modelling to reproduce two-dimensional peripheral spherical equivalent refraction

Qing Li and Fengzhou Fang

Biomed. Opt. Express 12(7), 3948-3964 (2021)  View: HTML | PDF

Laser Doppler holography of the anterior segment for blood flow imaging, eye tracking, and transparency assessment

Léo Puyo, Clémentine David, Rana Saad, Sami Saad, Josselin Gautier, José Alain Sahel, Vincent Borderie, Michel Paques, and Michael Atlan

Biomed. Opt. Express 12(7), 4478-4495 (2021)  View: HTML | PDF  [Suppl. Mat. (8)]

article thumbnail

A fly-through video of an OCT volume showing the back of the eye, with the Schlemm's canal highlighted in yellow. See Yao et al. Biomedical Optics Express 12, 3865-3877 (2021).

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