Label-free non-invasive subwavelength-resolution imaging using yeast cells as biological lenses

Chunlei Jiang, Hangyu Yue, Bing Yan, Taiji Dong, Xiangyu Cui, Peng Chen, and Zengbo Wang

Biomed. Opt. Express 12(11), 7113-7121 (2021)  View: HTML | PDF

Nb₂CT_x MXene-tilted fiber Bragg grating optofluidic system based on photothermal spectroscopy for pesticide detection

Wenjie Li, Yinping Miao, Tuan Guo, Kialiang Zhang, and Jianquan Yao

Biomed. Opt. Express 12(11), 7051-7063 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Label-free imaging of age-related cardiac structural changes in non-human primates using multiphoton nonlinear microscopy

Amara Khan, Fernanda Ramos-Gomes, Andrea Markus, Matthias Mietsch, Rabea Hinkel, and Frauke Alves

Biomed. Opt. Express 12(11), 7009-7023 (2021)  View: HTML | PDF  [Suppl. Mat. (4)]

Shot noise limits on binary detection in multiphoton imaging

Aaron K. LaViolette and Chris Xu

Biomed. Opt. Express 12(11), 7033-7048 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Automated phase unwrapping in digital holography with deep learning

Seonghwan Park, Youhyun Kim, and Inkyu Moon

Biomed. Opt. Express 12(11), 7064-7081 (2021)  View: HTML | PDF

Quantitative multi-height phase retrieval via a coded image sensor

Chengfei Guo, Shaowei Jiang, Pengming Song, Tianbo Wang, Xiaopeng Shao, Zibang Zhang, and Guoan Zheng

Biomed. Opt. Express 12(11), 7173-7184 (2021)  View: HTML | PDF

MicroHikari3D: an automated DIY digital microscopy platform with deep learning capabilities

J. Salido, P. T. Toledano, N. Vallez, O. Deniz, J. Ruiz-Santaquiteria, G. Cristobal, and G. Bueno

Biomed. Opt. Express 12(11), 7223-7243 (2021)  View: HTML | PDF

In vivo fluorescence molecular imaging of the vascular endothelial growth factor in rats with early diabetic retinopathy

Lu Zhang, Yunhe Ding, Xinjian Chen, Dehui Xiang, Fei Shi, Yanyun Chen, Shenshen Yan, Xinyuan Zhang, Jie Tian, Sobha Sivaprasad, Yang Du, Zhi Yang, and Bei Tian

Biomed. Opt. Express 12(11), 7185-7198 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Label-free monitoring of 3D cortical neuronal growth in vitro using optical diffraction tomography

Ariel J. Lee, DongJo Yoon, SeungYun Han, Herve Hugonnet, WeiSun Park, Je-Kyun Park, YoonKey Nam, and YongKeun Park

Biomed. Opt. Express 12(11), 6928-6939 (2021)  View: HTML | PDF

Mammalian complex III heme dynamics studied with pump-probe spectroscopy and red light illuminations

Sean P. O’Connor, Samantha M. Powell, John M. Rickman, Nathaniel J. Pope, Gary D. Noojin, Marlan O. Scully, Michael L. Denton, and Vladislav V. Yakovlev

Biomed. Opt. Express 12(11), 7082-7091 (2021)  View: HTML | PDF

One-dimensional scanning multiphoton imaging reveals prolonged calcium transient and sarcomere contraction in a zebrafish model of doxorubicin cardiotoxicity

Yu Kai Chao and Ian Liau

Biomed. Opt. Express 12(11), 7162-7172 (2021)  View: HTML | PDF

Ultracompact fluorescence smartphone attachment using built-in optics for protoporphyrin-IX quantification in skin

Brady Hunt, Samuel S. Streeter, Alberto J. Ruiz, M. Shane Chapman, and Brian W. Pogue

Biomed. Opt. Express 12(11), 6995-7008 (2021)  View: HTML | PDF  [Suppl. Mat. (4)]

Performance improvement of a silicon nitride ring resonator biosensor operated in the TM mode at 1310 nm

Lucía Castelló-Pedrero, María I. Gómez-Gómez, Jaime García-Rupérez, Amadeu Griol, and Alejandro Martínez

Biomed. Opt. Express 12(11), 7244-7260 (2021)  View: HTML | PDF

Modeling and optimization of galvanometric point-scanning temporal dynamics

Eric M. Tang and Yuankai K. Tao

Biomed. Opt. Express 12(11), 6701-6716 (2021)  View: HTML | PDF  [Suppl. Mat. (3)]

Combined anterior segment OCT and wavefront-based autorefractor using a shared beam

Marco Ruggeri, Giulia Belloni, Yu-Cherng Chang, Heather Durkee, Ettore Masetti, Florence Cabot, Sonia H. Yoo, Arthur Ho, Jean-Marie Parel, and Fabrice Manns

Biomed. Opt. Express 12(11), 6746-6761 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Digital ocular swept source optical coherence aberrometry

Stefan Georgiev, Abhishek Kumar, Oliver Findl, Nino Hirnschall, Michael Niederleithner, Milana Kendrisic, Wolfgang Drexler, and Rainer A. Leitgeb

Biomed. Opt. Express 12(11), 6762-6779 (2021)  View: HTML | PDF

Reconstruction of visible light optical coherence tomography images retrieved from discontinuous spectral data using a conditional generative adversarial network

Antonia Lichtenegger, Matthias Salas, Alexander Sing, Marcus Duelk, Roxane Licandro, Johanna Gesperger, Bernhard Baumann, Wolfgang Drexler, and Rainer A. Leitgeb

Biomed. Opt. Express 12(11), 6780-6795 (2021)  View: HTML | PDF

Polarization-sensitive optical coherence tomography in end-stage lung diseases: an ex vivo pilot study

Joy Willemse, Reinier R. Wener, Fabio Feroldi, Margherita Vaselli, Johanna M. Kwakkel-van Erp, Eduard A. van de Graaf, Erik Thunnissen, and Johannes F. de Boer

Biomed. Opt. Express 12(11), 6796-6813 (2021)  View: HTML | PDF  [Suppl. Mat. (5)]

Investigation of methods to extract confocal function parameters for the depth resolved determination of attenuation coefficients using OCT in intralipid samples, titanium oxide phantoms, and in vivo human retinas

Johannes Kübler, Vincent S. Zoutenbier, Arjen Amelink, Jörg Fischer, and Johannes F. de Boer

Biomed. Opt. Express 12(11), 6814-6830 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Three-dimensional dynamics optical coherence tomography for tumor spheroid evaluation

Ibrahim Abd El-Sadek, Arata Miyazawa, Larina Tzu-Wei Shen, Shuichi Makita, Pradipta Mukherjee, Antonia Lichtenegger, Satoshi Matsusaka, and Yoshiaki Yasuno

Biomed. Opt. Express 12(11), 6844-6863 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Visually guided chick ocular length and structural thickness variations assessed by swept-source optical coherence tomography

Feng Yan, Chen Wang, Jayla A. Wilson, Michael O’Connell, Sam Ton, Noah Davidson, Mourren Sibichan, Kari Chambers, Ahmed Ahmed, Jody Summers, and Qinggong Tang

Biomed. Opt. Express 12(11), 6864-6881 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Temporal phase evolution OCT for measurement of tissue deformation in the human retina in-vivo

Sylvia Desissaire, Florian Schwarzhans, Stefan Steiner, Clemens Vass, Georg Fischer, Michael Pircher, and Christoph K. Hitzenberger

Biomed. Opt. Express 12(11), 7092-7112 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Refined prefrontal working memory network as a neuromarker for Alzheimer’s disease

Eunho Kim, Jin-Woo Yu, Bomin Kim, Sung-Ho Lim, Sang-Ho Lee, Kwangsu Kim, Gowoon Son, Hyeon-Ae Jeon, Cheil Moon, Joon Sakong, and Ji-Woong Choi

Biomed. Opt. Express 12(11), 7199-7222 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Immediate effects of photobiomodulation therapy combined with a static magnetic field on the subsequent performance: a preliminary randomized crossover triple-blinded placebo-controlled trial

Ivo de Oliveira Aleixo-Junior, Ernesto Cesar Pinto Leal-Junior, Heliodora Leão Casalechi, Adriane Aver Vanin, Paulo Roberto Vicente de Paiva, Caroline dos Santos Monteiro Machado, Luana Barbosa Dias, Matheus Marinho Aguiar Lino, Adeilson Matias Teixeira, Douglas Scott Johnson, and Shaiane Silva Tomazoni

Biomed. Opt. Express 12(11), 6940-6953 (2021)  View: HTML | PDF

Plastic embedding for precise imaging of large-scale biological tissues labeled with multiple fluorescent dyes and proteins

Miao Ren, Jiaojiao Tian, Qingtao Sun, Siqi Chen, Ting Luo, Xueyan Jia, Tao Jiang, Qingming Luo, Hui Gong, and Xiangning Li

Biomed. Opt. Express 12(11), 6730-6745 (2021)  View: HTML | PDF

Laser induced forward transfer isolating complex-shaped cell by beam shaping

Peng Liang, Lindong Shang, Yuntong Wang, Martin J. Booth, and Bei Li

Biomed. Opt. Express 12(11), 7024-7032 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

High-resolution photoacoustic/ultrasound imaging of the porcine stomach wall: an ex vivo feasibility study

Jaewoo Kim, Joongho Ahn, Gwansuk Kang, Joo Ha Hwang, and Chulhong Kim

Biomed. Opt. Express 12(11), 6717-6729 (2021)  View: HTML | PDF

Suppression of motion artifacts in intravascular photoacoustic image sequences

Zheng Sun and Jiejie Du

Biomed. Opt. Express 12(11), 6909-6927 (2021)  View: HTML | PDF

Low-consumption photoacoustic method to measure liquid viscosity

Yingying Zhou, Chao Liu, Xiazi Huang, Xiang Qian, Lidai Wang, and Puxiang Lai

Biomed. Opt. Express 12(11), 7139-7148 (2021)  View: HTML | PDF

Effects of high intensity non-ionizing terahertz radiation on human skin fibroblasts

Dmitry S. Sitnikov, Inna V. Ilina, Veronika A. Revkova, Sergey A. Rodionov, Svetlana A. Gurova, Rimma O. Shatalova, Alexey V. Kovalev, Andrey V. Ovchinnikov, Oleg V. Chefonov, Mikhail A. Konoplyannikov, Vladimir A. Kalsin, and Vladimir P. Baklaushev

Biomed. Opt. Express 12(11), 7122-7138 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Fast diffuse correlation spectroscopy with a low-cost, fiber-less embedded diode laser

Arindam Biswas, Sadhu Moka, Andreas Muller, and Ashwin B. Parthasarathy

Biomed. Opt. Express 12(11), 6686-6700 (2021)  View: HTML | PDF

Discriminating turbid media by scatterer size and scattering coefficient using backscattered linearly and circularly polarized light

Michael D. Singh and I. Alex Vitkin

Biomed. Opt. Express 12(11), 6831-6843 (2021)  View: HTML | PDF

Multimodal hyperspectral fluorescence and spatial frequency domain imaging for tissue health diagnostics of the oral cavity

Ben E. Urban and Hrebesh Molly Subhash

Biomed. Opt. Express 12(11), 6954-6968 (2021)  View: HTML | PDF

Noninvasive and early diagnosis of acquired brain injury using fluorescence imaging in the NIR-II window

Xinyan Jiang, Rui Pu, Cheng Wang, Jiale Xu, Yaohui Tang, Shuhong Qi, Qiuqiang Zhan, Xunbin Wei, and Bobo Gu

Biomed. Opt. Express 12(11), 6984-6994 (2021)  View: HTML | PDF

Accuracy of diffuse correlation spectroscopy measurements of cerebral blood flow when using a three-layer analytical model

Hongting Zhao, Eashani Sathialingam, and Erin M. Buckley

Biomed. Opt. Express 12(11), 7149-7161 (2021)  View: HTML | PDF

A scalable, multi-wavelength, broad bandwidth frequency-domain near-infrared spectroscopy platform for real-time quantitative tissue optical imaging

Roy A. Stillwell, Vincent J. Kitsmiller, Alicia Y. Wei, Alyssa Chong, Lyla Senn, and Thomas D. O’Sullivan

Biomed. Opt. Express 12(11), 7261-7279 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Gamut mapping based image enhancement algorithm for color deficiencies

Lihao Xu, Qinyuan Li, Xiaoxuan Liu, Qiang Xu, and Ming Ronnier Luo

Biomed. Opt. Express 12(11), 6882-6896 (2021)  View: HTML | PDF

The random walk of accommodation fluctuations

Charles-Edouard Leroux, Conor Leahy, Christophe Fontvieille, and Fabrice Bardin

Biomed. Opt. Express 12(11), 6897-6908 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Deep level set method for optic disc and cup segmentation on fundus images

Yaoyue Zheng, Xuetao Zhang, Xiayu Xu, Zhiqiang Tian, and Shaoyi Du

Biomed. Opt. Express 12(11), 6969-6983 (2021)  View: HTML | PDF

Empirical assessment of laser safety for photoacoustic-guided liver surgeries: erratum

Jiaqi Huang, Alycen Wiacek, Kelley M. Kempski, Theron Palmer, Jessica Izzi, Sarah Beck, and Muyinatu A. Lediju Bell

Biomed. Opt. Express 12(11), 7049-7050 (2021)  View: HTML | PDF