Diffuse optical tomography to measure functional changes during motor tasks: a motor imagery study

Estefania Hernandez-Martin, Francisco Marcano, Cristian Modroño, Niels Janssen, and Jose Luis González-Mora

Biomed. Opt. Express 11(11), 6049-6067 (2020)  View: HTML | PDF

Simultaneous diffuse optical and bioluminescence tomography to account for signal attenuation to improve source localization

Alexander Bentley, Jonathan E. Rowe, and Hamid Dehghani

Biomed. Opt. Express 11(11), 6428-6444 (2020)  View: HTML | PDF

Autofluorescence guided welding of heart tissue by laser pulse bursts at 1550 nm

Karina Litvinova, Maria Chernysheva, Berthold Stegemann, and Francisco Leyva

Biomed. Opt. Express 11(11), 6271-6280 (2020)  View: HTML | PDF

Non-invasive in situ monitoring of bone scaffold activity by speckle pattern analysis

Vahideh Farzam Rad, Majid Panahi, Ramin Jamali, Ahmad Darudi, and Ali-Reza Moradi

Biomed. Opt. Express 11(11), 6324-6336 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Probe-hosted large area silicon photomultiplier and high-throughput timing electronics for enhanced performance time-domain functional near-infrared spectroscopy

L. Di Sieno, A. Behera, S. Rohilla, E. Ferocino, D. Contini, A. Torricelli, B. Krämer, F. Koberling, A. Pifferi, and A. Dalla Mora

Biomed. Opt. Express 11(11), 6389-6412 (2020)  View: HTML | PDF

Towards detection of brain injury using multimodal non-invasive neuromonitoring in adults undergoing extracorporeal membrane oxygenation

Irfaan A. Dar, Imad R. Khan, Ross K. Maddox, Olga Selioutski, Kelly L. Donohue, Mark A. Marinescu, Sunil M. Prasad, Nadim H. Quazi, Jack S. Donlon, Emily A. Loose, Gabriel A. Ramirez, Jingxuan Ren, Joseph B. Majeski, Kenneth Abramson, Turgut Durduran, David R. Busch, and Regine Choe

Biomed. Opt. Express 11(11), 6551-6569 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Multi-speckle diffuse correlation spectroscopy to measure cerebral blood flow

K. Murali and Hari M. Varma

Biomed. Opt. Express 11(11), 6699-6709 (2020)  View: HTML | PDF

Fourier domain diffuse correlation spectroscopy with heterodyne holographic detection

Edward James and Samuel Powell

Biomed. Opt. Express 11(11), 6755-6779 (2020)  View: HTML | PDF

Hybrid deep learning network for vascular segmentation in photoacoustic imaging

Alan Yilun Yuan, Yang Gao, Liangliang Peng, Lingxiao Zhou, Jun Liu, Siwei Zhu, and Wei Song

Biomed. Opt. Express 11(11), 6445-6457 (2020)  View: HTML | PDF

Background-free fibre optic Brillouin probe for remote mapping of micromechanics

YuChen Xiang, Carin Basirun, Joshua Chou, Majid E. Warkiani, Peter Török, Yingying Wang, Shoufei Gao, and Irina V. Kabakova

Biomed. Opt. Express 11(11), 6687-6698 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Bead-based multiplex detection of dengue biomarkers in a portable imaging device

Xilong Yuan, Srishti Garg, Kevin De Haan, Frederic A. Fellouse, Anupriya Gopalsamy, Jan Tykvart, Sachdev S. Sidhu, Manoj M. Varma, Parama Pal, Edith M. Hillan, James Jiahua Dou, and J. Stewart Aitchison

Biomed. Opt. Express 11(11), 6154-6167 (2020)  View: HTML | PDF

Plasmonic-based impedance microspectroscopy of optically heterogeneous samples

Sidahmed A. Abayzeed

Biomed. Opt. Express 11(11), 6168-6180 (2020)  View: HTML | PDF

Three-dimensional imaging of intact porcine cochlea using tissue clearing and custom-built light-sheet microscopy

Adele Moatti, Yuheng Cai, Chen Li, Tyler Sattler, Laura Edwards, Jorge Piedrahita, Frances S. Ligler, and Alon Greenbaum

Biomed. Opt. Express 11(11), 6181-6196 (2020)  View: HTML | PDF  [Suppl. Mat. (8)]

Volumetric Lissajous confocal microscopy with tunable spatiotemporal resolution

Takahiro Deguchi, Paolo Bianchini, Gemma Palazzolo, Michele Oneto, Alberto Diaspro, and Martí Duocastella

Biomed. Opt. Express 11(11), 6293-6310 (2020)  View: HTML | PDF  [Suppl. Mat. (6)]

Assessment of progressive alterations in collagen organization in the postoperative conjunctiva by multiphoton microscopy

Li-Fong Seet, Stephanie W. L. Chu, Xiao Teng, Li Zhen Toh, and Tina T. Wong

Biomed. Opt. Express 11(11), 6495-6515 (2020)  View: HTML | PDF

Multi-resolution open-top light-sheet microscopy to enable efficient 3D pathology workflows

Lindsey A. Barner, Adam K. Glaser, Hongyi Huang, Lawrence D. True, and Jonathan T. C. Liu

Biomed. Opt. Express 11(11), 6605-6619 (2020)  View: HTML | PDF

Axial resolution improvement of two-photon microscopy by multi-frame reconstruction and adaptive optics

Shiwei Ye, Yixuan Yin, Jing Yao, Jun Nie, Yuchen Song, Yufeng Gao, Jia Yu, Hui Li, Peng Fei, and Wei Zheng

Biomed. Opt. Express 11(11), 6634-6648 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Erythrocyte volumetric measurements in imaging flow cytometry using simultaneous three-wavelength digital holographic microscopy

Nir A. Turko and Natan T. Shaked

Biomed. Opt. Express 11(11), 6649-6658 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Imaging of PD-L1 in single cancer cells by SERS-based hyperspectral analysis

Wei Zhang, Jake S. Rhodes, Kevin R. Moon, Beatrice S. Knudsen, Linda Nokolova, and Anhong Zhou

Biomed. Opt. Express 11(11), 6197-6210 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Enrichment and ratiometric detection of circulating tumor cells using PSMA- and folate receptor-targeted magnetic and surface-enhanced Raman scattering nanoparticles

Pradyumna Kedarisetti, Vincent R. Bouvet, Wei Shi, Cody N. Bergman, Jennifer Dufour, Afshin Kashani Ilkhechi, Kevan L. Bell, Robert J. Paproski, John D. Lewis, Frank R. Wuest, and Roger J. Zemp

Biomed. Opt. Express 11(11), 6211-6230 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Evaluation of bone perfusion during open orthopedic surgery using quantitative dynamic contrast-enhanced fluorescence imaging

I. Leah Gitajn, Jonathan T. Elliott, Jason R. Gunn, Alberto J. Ruiz, Eric R. Henderson, Brian W. Pogue, and Shudong Jiang

Biomed. Opt. Express 11(11), 6458-6469 (2020)  View: HTML | PDF  [Suppl. Mat. (2)]

Influence of FRET and fluorescent protein maturation on the quantification of binding affinity with dual-channel fluorescence cross-correlation spectroscopy

Varun K. A. Sreenivasan, Matthew S. Graus, Rashmi R. Pillai, Zhengmin Yang, Jesse Goyette, and Katharina Gaus

Biomed. Opt. Express 11(11), 6137-6153 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Light-cell interactions in depth-resolved optogenetics

Sonja Johannsmeier, Johannes Wenzel, Maria L. Torres-Mapa, Sebastian Junge, Philipp Sasse, Joshua D. Stockhausen, Tammo Ripken, Dag Heinemann, and Alexander Heisterkamp

Biomed. Opt. Express 11(11), 6536-6550 (2020)  View: HTML | PDF

IA-net: informative attention convolutional neural network for choroidal neovascularization segmentation in OCT images

Xiaoming Xi, Xianjing Meng, Zheyun Qin, Xiushan Nie, Yilong Yin, and Xinjian Chen

Biomed. Opt. Express 11(11), 6122-6136 (2020)  View: HTML | PDF

Analysis of attenuation coefficient estimation in Fourier-domain OCT of semi-infinite media

Babak Ghafaryasl, Koenraad A. Vermeer, Jeroen Kalkman, Tom Callewaert, Johannes F. de Boer, and Lucas J. Van Vliet

Biomed. Opt. Express 11(11), 6093-6107 (2020)  View: HTML | PDF

Optical coherence tomography-based tissue dynamics imaging for longitudinal and drug response evaluation of tumor spheroids

Ibrahim Abd El-Sadek, Arata Miyazawa, Larina Tzu-Wei Shen, Shuichi Makita, Shinichi Fukuda, Toshiharu Yamashita, Yuki Oka, Pradipta Mukherjee, Satoshi Matsusaka, Tetsuro Oshika, Hideaki Kano, and Yoshiaki Yasuno

Biomed. Opt. Express 11(11), 6231-6248 (2020)  View: HTML | PDF

Multi-meridian corneal imaging of air-puff induced deformation for improved detection of biomechanical abnormalities

Andrea Curatolo, Judith S. Birkenfeld, Eduardo Martinez-Enriquez, James A. Germann, Geethika Muralidharan, Jesús Palací, Daniel Pascual, Ashkan Eliasy, Ahmed Abass, Jędrzej Solarski, Karol Karnowski, Maciej Wojtkowski, Ahmed Elsheikh, and Susana Marcos

Biomed. Opt. Express 11(11), 6337-6355 (2020)  View: HTML | PDF  [Suppl. Mat. (5)]

Towards label-free 3D segmentation of optical coherence tomography images of the optic nerve head using deep learning

Sripad Krishna Devalla, Tan Hung Pham, Satish Kumar Panda, Liang Zhang, Giridhar Subramanian, Anirudh Swaminathan, Chin Zhi Yun, Mohan Rajan, Sujatha Mohan, Ramaswami Krishnadas, Vijayalakshmi Senthil, John Mark S. De Leon, Tin A. Tun, Ching-Yu Cheng, Leopold Schmetterer, Shamira Perera, Tin Aung, Alexandre H. Thiéry, and Michaël J. A. Girard

Biomed. Opt. Express 11(11), 6356-6378 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Polarization sensitive optical coherence tomography for imaging microvascular information within living tissue without polarization-induced artifacts

Peijun Tang and Ruikang K. Wang

Biomed. Opt. Express 11(11), 6379-6388 (2020)  View: HTML | PDF

Repetitive optical coherence elastography measurements with blinking nanobombs

Paul Boerner, Dmitry Nevozhay, Maryam Hatamimoslehabadi, Harshdeep Singh Chawla, Fernando Zvietcovich, Salavat Aglyamov, Kirill V. Larin, and Konstantin V. Sokolov

Biomed. Opt. Express 11(11), 6659-6673 (2020)  View: HTML | PDF

Relative retinal flow velocity detection using optical coherence tomography angiography imaging

Dmitry Richter, Ali M. Fard, Jochen Straub, Wei Wei, Qinqin Zhang, and Ruikang K. Wang

Biomed. Opt. Express 11(11), 6710-6720 (2020)  View: HTML | PDF

Capability of physically reasonable OCT-based differentiation between intact brain tissues, human brain gliomas of different WHO grades, and glioma model 101.8 from rats

I. N. Dolganova, P. V. Aleksandrova, P. V. Nikitin, A. I. Alekseeva, N. V. Chernomyrdin, G. R. Musina, S. T. Beshplav, I. V. Reshetov, A. A. Potapov, V. N. Kurlov, V. V. Tuchin, and K. I. Zaytsev

Biomed. Opt. Express 11(11), 6780-6798 (2020)  View: HTML | PDF

Flexible A-scan rate MHz-OCT: efficient computational downscaling by coherent averaging

Tom Pfeiffer, Madita Göb, Wolfgang Draxinger, Sebastian Karpf, Jan Philip Kolb, and Robert Huber

Biomed. Opt. Express 11(11), 6799-6811 (2020)  View: HTML | PDF

Ultrastructure and hemodynamics of microaneurysms in retinal vein occlusion examined by an offset pinhole adaptive optics scanning light ophthalmoscope

Shin Kadomoto, Yuki Muraoka, Akihito Uji, Ryosuke Tamiya, Sotaro Ooto, Tomoaki Murakami, Yasuyuki Oritani, Kentaro Kawai, and Akitaka Tsujikawa

Biomed. Opt. Express 11(11), 6078-6092 (2020)  View: HTML | PDF  [Suppl. Mat. (5)]

Spectroscopic detection of traumatic brain injury severity and biochemistry from the retina

Carl Banbury, Iain Styles, Neil Eisenstein, Elisa R. Zanier, Gloria Vegliante, Antonio Belli, Ann Logan, and Pola Goldberg Oppenheimer

Biomed. Opt. Express 11(11), 6249-6261 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Canine mammary cancer diagnosis from quantitative properties of nonlinear optical images

Luana A. Reis, Ana P. V. Garcia, Egleidson F. A. Gomes, Francis G. J. Longford, Jeremy G. Frey, Geovanni D. Cassali, and Ana M. de Paula

Biomed. Opt. Express 11(11), 6413-6427 (2020)  View: HTML | PDF

Rapid imaging of tympanic membrane vibrations in humans

Matan Hamra, Shadi Shinnawi, Mauricio Cohen Vaizer, and Dvir Yelin

Biomed. Opt. Express 11(11), 6470-6479 (2020)  View: HTML | PDF  [Suppl. Mat. (3)]

Deep learning-based light scattering microfluidic cytometry for label-free acute lymphocytic leukemia classification

Jing Sun, Lan Wang, Qiao Liu, Attila Tárnok, and Xuantao Su

Biomed. Opt. Express 11(11), 6674-6686 (2020)  View: HTML | PDF

Optical clearing agent increases effectiveness of photodynamic therapy in a mouse model of cutaneous melanoma: an analysis by Raman microspectroscopy

Letícia Palombo Martinelli, Ievgeniia Iermak, Lilian Tan Moriyama, Michelle Barreto Requena, Layla Pires, and Cristina Kurachi

Biomed. Opt. Express 11(11), 6516-6527 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Bidirectional optical neuromodulation using capacitive charge-transfer

Rustamzhon Melikov, Shashi Bhushan Srivastava, Onuralp Karatum, Itir Bakis Dogru-Yuksel, Ugur Meric Dikbas, Ibrahim Halil Kavakli, and Sedat Nizamoglu

Biomed. Opt. Express 11(11), 6068-6077 (2020)  View: HTML | PDF

Effect of laser pulse shaping on photoacoustic dosimetry in retinal models

Robert B. Brown, Suzie Dufour, Pascal Deladurantaye, Nolwenn Le Bouch, Pascal Gallant, Sébastien Méthot, Patrick J. Rochette, and Ozzy Mermut

Biomed. Opt. Express 11(11), 6590-6604 (2020)  View: HTML | PDF

In vivo intravascular photoacoustic imaging at a high speed of 100 frames per second

Zhihua Xie, Chengyou Shu, Daya Yang, Hao Chen, Chaobin Chen, Gang Dai, Kwok Ho Lam, Jinke Zhang, Xiatian Wang, Zonghai Sheng, Duyang Gao, Chengbo Liu, Liang Song, and Xiaojing Gong

Biomed. Opt. Express 11(11), 6721-6731 (2020)  View: HTML | PDF  [Suppl. Mat. (6)]

Differentiation of burn wounds in an in vivo porcine model using terahertz spectroscopy

Omar B. Osman, Timothy Jack Tan, Sam Henry, Adelaide Warsen, Navid Farr, Abbi M. McClintic, Yak-Nam Wang, Saman Arbabi, and M. Hassan Arbab

Biomed. Opt. Express 11(11), 6528-6535 (2020)  View: HTML | PDF

Hybrid mesh and voxel based Monte Carlo algorithm for accurate and efficient photon transport modeling in complex bio-tissues

Shijie Yan and Qianqian Fang

Biomed. Opt. Express 11(11), 6262-6270 (2020)  View: HTML | PDF

Numerical investigation of depth-sensitive diffuse reflectance and fluorescence measurements on murine subcutaneous tissue with growing solid tumors

Evan Carrico, Tengfei Sun, and Caigang Zhu

Biomed. Opt. Express 11(11), 6311-6323 (2020)  View: HTML | PDF

Tissue optical properties combined with machine learning enables estimation of articular cartilage composition and functional integrity

Iman Kafian-Attari, Ervin Nippolainen, Dmitry Semenov, Markku Hauta-Kasari, Juha Töyräs, and Isaac O. Afara

Biomed. Opt. Express 11(11), 6480-6494 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Space-enhanced time-domain diffuse optics for determination of tissue optical properties in two-layered structures

Lin Yang, Heidrun Wabnitz, Thomas Gladytz, Aleh Sudakou, Rainer Macdonald, and Dirk Grosenick

Biomed. Opt. Express 11(11), 6570-6589 (2020)  View: HTML | PDF

Subdiffuse scattering and absorption model for single fiber reflectance spectroscopy

Anouk L. Post, Dirk J. Faber, Henricus J. C. M. Sterenborg, and Ton G. van Leeuwen

Biomed. Opt. Express 11(11), 6620-6633 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Signal quality index: an algorithm for quantitative assessment of functional near infrared spectroscopy signal quality

M. Sofía Sappia, Naser Hakimi, Willy N. J. M. Colier, and Jörn M. Horschig

Biomed. Opt. Express 11(11), 6732-6754 (2020)  View: HTML | PDF

Utilizing minicomputer technology for low-cost photorefraction: a feasibility study

Rajat Agarwala, Alexander Leube, and Siegfried Wahl

Biomed. Opt. Express 11(11), 6108-6121 (2020)  View: HTML | PDF

Portable ultra-widefield fundus camera for multispectral imaging of the retina and choroid

Devrim Toslak, Taeyoon Son, Muhammet Kazim Erol, Hoonsup Kim, Tae-Hoon Kim, R. V. Paul Chan, and Xincheng Yao

Biomed. Opt. Express 11(11), 6281-6292 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]