Abstract

This study proposed an ultrahigh-resolution multi-contrast optical coherence tomography system integrated with fundus photography for in vivo retinal imaging of rodents. A supercontinuum light source was used in the system, providing an axial resolution of less than 3 µm within 1.8 mm (in the tissue). Three types of tissue contrast based on backscattered intensity, phase retardation, and microvasculature at a capillary level can be simultaneously obtained using the proposed system. Pigmented Long-Evans, non-pigmented (albino) Sprague Dawley, and Royal College of Surgeons rats were imaged and compared. In vivo imaging results were validated with histology.

© 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

Full Article  |  PDF Article
OSA Recommended Articles
Optical microangiography of retina and choroid and measurement of total retinal blood flow in mice

Zhongwei Zhi, Xin Yin, Suzan Dziennis, Tomasz Wietecha, Kelly L. Hudkins, Charles E. Alpers, and Ruikang K Wang
Biomed. Opt. Express 3(11) 2976-2986 (2012)

Polarization properties of single layers in the posterior eyes of mice and rats investigated using high resolution polarization sensitive optical coherence tomography

Stanislava Fialová, Marco Augustin, Martin Glösmann, Tanja Himmel, Sabine Rauscher, Marion Gröger, Michael Pircher, Christoph K. Hitzenberger, and Bernhard Baumann
Biomed. Opt. Express 7(4) 1479-1495 (2016)

In vivo volumetric imaging of chicken retina with ultrahigh-resolution spectral domain optical coherence tomography

Alireza Akhlagh Moayed, Sepideh Hariri, Eun Sun Song, Vivian Choh, and Kostadinka Bizheva
Biomed. Opt. Express 2(5) 1268-1274 (2011)

References

  • View by:
  • |
  • |
  • |

  1. S. P. Daiger, S. J. Bowne, and L. S. Sullivan, “Perspective on genes and mutations causing retinitis pigmentosa,” Arch. Ophthalmol. 125(2), 151–158 (2007).
    [Crossref] [PubMed]
  2. S. Nusinowitz, Y. Wang, P. Kim, S. Habib, R. Baron, Y. Conley, and M. Gorin, “Retinal Structure in Pre-Clinical Age-Related Macular Degeneration,” Curr. Eye Res. 43(3), 376–382 (2018).
    [Crossref] [PubMed]
  3. E. Vecino, “[Animal models in the study of the glaucoma: past, present and future],” Arch. Soc. Esp. Oftalmol. 83(9), 517–519 (2008).
    [Crossref] [PubMed]
  4. E. L. Fletcher, A. I. Jobling, U. Greferath, S. A. Mills, M. Waugh, T. Ho, R. U. de Iongh, J. A. Phipps, and K. A. Vessey, “Studying age-related macular degeneration using animal models,” Optom. Vis. Sci. 91(8), 878–886 (2014).
    [Crossref] [PubMed]
  5. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
    [Crossref] [PubMed]
  6. W. Yuan, J. Mavadia-Shukla, J. Xi, W. Liang, X. Yu, S. Yu, and X. Li, “Optimal operational conditions for supercontinuum-based ultrahigh-resolution endoscopic OCT imaging,” Opt. Lett. 41(2), 250–253 (2016).
    [Crossref] [PubMed]
  7. N. Nishizawa, H. Kawagoe, M. Yamanaka, M. Matsushima, K. Mori, and T. Kawabe, “Wavelength Dependence of Ultrahigh-Resolution Optical Coherence Tomography Using Supercontinuum for Biomedical Imaging,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1–15 (2019).
    [Crossref]
  8. J. Barrick, A. Doblas, M. Gardner, P. Sears, L. Ostrowski, and A. L. Oldenburg, “Supercontinuum Parallel Line-field Optical Coherence Tomography for High Sensitivity, Kilohertz Frame Rate Imaging,” in Optics in the Life Sciences Congress (Optical Society of America, San Diego, California, 2017), p. BoM4A.1.
  9. U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, “Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases,” Invest. Ophthalmol. Vis. Sci. 46(9), 3393–3402 (2005).
    [Crossref] [PubMed]
  10. W. Choi, N. K. Waheed, E. M. Moult, M. Adhi, B. Lee, T. De Carlo, V. Jayaraman, C. R. Baumal, J. S. Duker, and J. G. Fujimoto, “Ultrahigh Speed Swept Source Optical Coherence Tomography Angiography of Retinal and Choriocapillaris Alterations in Diabetic Patients with and without Retinopathy,” Retina 37(1), 11–21 (2017).
    [Crossref] [PubMed]
  11. M. Battaglia Parodi, M. V. Cicinelli, A. Rabiolo, L. Pierro, M. Gagliardi, G. Bolognesi, and F. Bandello, “Vessel density analysis in patients with retinitis pigmentosa by means of optical coherence tomography angiography,” Br. J. Ophthalmol. 101(4), 428–432 (2017).
    [Crossref] [PubMed]
  12. E. Pilotto, L. Frizziero, A. R. Daniele, E. Convento, E. Longhin, F. Guidolin, R. Parrozzani, F. Cavarzeran, and E. Midena, “Early OCT angiography changes of type 1 CNV in exudative AMD treated with anti-VEGF,” Br. J. Ophthalmol. 2018, 311752 (2018).
    [Crossref] [PubMed]
  13. J. Yi, S. Chen, V. Backman, and H. F. Zhang, “In vivo functional microangiography by visible-light optical coherence tomography,” Biomed. Opt. Express 5(10), 3603–3612 (2014).
    [Crossref] [PubMed]
  14. Q. Liu, S. Chen, B. Soetikno, W. Liu, S. Tong, and H. Zhang, “Monitoring acute stroke in mouse model using laser speckle imaging-guided visible-light optical coherence tomography,” IEEE Trans. Biomed. Eng. 65, 2136 (2017).
    [PubMed]
  15. S. P. Chong, C. W. Merkle, C. Leahy, H. Radhakrishnan, and V. J. Srinivasan, “Quantitative microvascular hemoglobin mapping using visible light spectroscopic Optical Coherence Tomography,” Biomed. Opt. Express 6(4), 1429–1450 (2015).
    [Crossref] [PubMed]
  16. J. Yi, W. Liu, S. Chen, V. Backman, N. Sheibani, C. M. Sorenson, A. A. Fawzi, R. A. Linsenmeier, and H. F. Zhang, “Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation,” Light Sci. Appl. 4(9), e334 (2015).
    [Crossref] [PubMed]
  17. J. Dwelle, S. Liu, B. Wang, A. McElroy, D. Ho, M. K. Markey, T. Milner, and H. G. Rylander, “Thickness, phase retardation, birefringence, and reflectance of the retinal nerve fiber layer in normal and glaucomatous non-human primates,” Invest. Ophthalmol. Vis. Sci. 53(8), 4380–4395 (2012).
    [Crossref] [PubMed]
  18. M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Polarization sensitive optical coherence tomography in the human eye,” Prog. Retin. Eye Res. 30(6), 431–451 (2011).
    [Crossref] [PubMed]
  19. C. Schütze, M. Wedl, B. Baumann, M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Progression of retinal pigment epithelial atrophy in antiangiogenic therapy of neovascular age-related macular degeneration,” Am. J. Ophthalmol. 159(6), 1100–1114 (2015).
    [Crossref] [PubMed]
  20. S. Fialová, M. Augustin, M. Glösmann, T. Himmel, S. Rauscher, M. Gröger, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Polarization properties of single layers in the posterior eyes of mice and rats investigated using high resolution polarization sensitive optical coherence tomography,” Biomed. Opt. Express 7(4), 1479–1495 (2016).
    [Crossref] [PubMed]
  21. J. Lammer, M. Bolz, B. Baumann, M. Pircher, B. Gerendas, F. Schlanitz, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Detection and analysis of hard exudates by polarization-sensitive optical coherence tomography in patients with diabetic maculopathy,” Invest. Ophthalmol. Vis. Sci. 55(3), 1564–1571 (2014).
    [Crossref] [PubMed]
  22. B. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. Tearney, B. Bouma, and J. de Boer, “Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 microm,” Opt. Express 13(11), 3931–3944 (2005).
    [Crossref] [PubMed]
  23. B. Park, M. Pierce, B. Cense, and J. de Boer, “Real-time multi-functional optical coherence tomography,” Opt. Express 11(7), 782–793 (2003).
    [Crossref] [PubMed]
  24. H. Ren, Z. Ding, Y. Zhao, J. Miao, J. S. Nelson, and Z. Chen, “Phase-resolved functional optical coherence tomography: simultaneous imaging of in situ tissue structure, blood flow velocity, standard deviation, birefringence, and Stokes vectors in human skin,” Opt. Lett. 27(19), 1702–1704 (2002).
    [Crossref] [PubMed]
  25. M. C. Pierce, B. Hyle Park, B. Cense, and J. F. de Boer, “Simultaneous intensity, birefringence, and flow measurements with high-speed fiber-based optical coherence tomography,” Opt. Lett. 27(17), 1534–1536 (2002).
    [Crossref] [PubMed]
  26. H. Wang, A. J. Black, J. Zhu, T. W. Stigen, M. K. Al-Qaisi, T. I. Netoff, A. Abosch, and T. Akkin, “Reconstructing micrometer-scale fiber pathways in the brain: multi-contrast optical coherence tomography based tractography,” Neuroimage 58(4), 984–992 (2011).
    [Crossref] [PubMed]
  27. M. J. Ju, Y. J. Hong, S. Makita, Y. Lim, K. Kurokawa, L. Duan, M. Miura, S. Tang, and Y. Yasuno, “Advanced multi-contrast Jones matrix optical coherence tomography for Doppler and polarization sensitive imaging,” Opt. Express 21(16), 19412–19436 (2013).
    [Crossref] [PubMed]
  28. M. Augustin, S. Fialová, T. Himmel, M. Glösmann, T. Lengheimer, D. J. Harper, R. Plasenzotti, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Multi-Functional OCT Enables Longitudinal Study of Retinal Changes in a VLDLR Knockout Mouse Model,” PLoS One 11(10), e0164419 (2016).
    [Crossref] [PubMed]
  29. S. Rösch, C. Aretzweiler, F. Müller, and P. Walter, “Evaluation of Retinal Function and Morphology of the Pink-Eyed Royal College of Surgeons (RCS) Rat: A Comparative Study of in Vivo and in Vitro Methods,” Curr. Eye Res. 42(2), 273–281 (2017).
    [Crossref] [PubMed]
  30. R. C. Ryals, M. D. Andrews, S. Datta, A. S. Coyner, C. M. Fischer, Y. Wen, M. E. Pennesi, and T. J. McGill, “Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence Tomography,” Invest. Ophthalmol. Vis. Sci. 58(3), 1378–1386 (2017).
    [Crossref] [PubMed]
  31. W. C. Kuo, C. M. Lai, Y. S. Huang, C. Y. Chang, and Y. M. Kuo, “Balanced detection for spectral domain optical coherence tomography,” Opt. Express 21(16), 19280–19291 (2013).
    [Crossref] [PubMed]
  32. W. C. Kuo, N. K. Chou, C. Chou, C. M. Lai, H. J. Huang, S. S. Wang, and J. J. Shyu, “Polarization-sensitive optical coherence tomography for imaging human atherosclerosis,” Appl. Opt. 46(13), 2520–2527 (2007).
    [Crossref] [PubMed]
  33. C. L. Chen and R. K. Wang, “Optical coherence tomography based angiography [Invited],” Biomed. Opt. Express 8(2), 1056–1082 (2017).
    [Crossref] [PubMed]
  34. J. Lee, V. Srinivasan, H. Radhakrishnan, and D. A. Boas, “Motion correction for phase-resolved dynamic optical coherence tomography imaging of rodent cerebral cortex,” Opt. Express 19(22), 21258–21270 (2011).
    [Crossref] [PubMed]
  35. E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
    [Crossref] [PubMed]
  36. J. E. Dowling and R. L. Sidman, “Inherited retinal dystrophy in the rat,” J. Cell Biol. 14(1), 73–109 (1962).
    [Crossref] [PubMed]
  37. W. Eickhoff, Y. Yen, and R. Ulrich, “Wavelength dependence of birefringence in single-mode fiber,” Appl. Opt. 20(19), 3428–3435 (1981).
    [Crossref] [PubMed]
  38. M. Friedlander, “Fibrosis and diseases of the eye,” J. Clin. Invest. 117(3), 576–586 (2007).
    [Crossref] [PubMed]
  39. H. J. Zambarakji, D. J. Keegan, T. M. Holmes, A. S. Halfyard, M. P. Villegas-Perez, D. G. Charteris, F. W. Fitzke, J. Greenwood, and R. D. Lund, “High resolution imaging of fluorescein patterns in RCS rat retinae and their direct correlation with histology,” Exp. Eye Res. 82(1), 164–171 (2006).
    [Crossref] [PubMed]
  40. H. Liu, J. Tang, Y. Du, A. Saadane, D. Tonade, I. Samuels, A. Veenstra, K. Palczewski, and T. S. Kern, “Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes,” Invest. Ophthalmol. Vis. Sci. 57(10), 4272–4281 (2016).
    [Crossref] [PubMed]
  41. Y. Feng, Y. Wang, Z. Yang, L. Wu, S. Hoffmann, T. Wieland, N. Gretz, and H. P. Hammes, “Chronic hyperglycemia inhibits vasoregression in a transgenic model of retinal degeneration,” Acta Diabetol. 51(2), 211–218 (2014).
    [Crossref] [PubMed]
  42. T. E. de Gooyer, K. A. Stevenson, P. Humphries, D. A. Simpson, T. A. Gardiner, and A. W. Stitt, “Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration,” Invest. Ophthalmol. Vis. Sci. 47(12), 5561–5568 (2006).
    [Crossref] [PubMed]
  43. J. S. Penn, S. Li, and M. I. Naash, “Ambient hypoxia reverses retinal vascular attenuation in a transgenic mouse model of autosomal dominant retinitis pigmentosa,” Invest. Ophthalmol. Vis. Sci. 41(12), 4007–4013 (2000).
    [PubMed]
  44. A. H. Milam, Z. Y. Li, and R. N. Fariss, “Histopathology of the human retina in retinitis pigmentosa,” Prog. Retin. Eye Res. 17(2), 175–205 (1998).
    [PubMed]

2019 (1)

N. Nishizawa, H. Kawagoe, M. Yamanaka, M. Matsushima, K. Mori, and T. Kawabe, “Wavelength Dependence of Ultrahigh-Resolution Optical Coherence Tomography Using Supercontinuum for Biomedical Imaging,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1–15 (2019).
[Crossref]

2018 (2)

S. Nusinowitz, Y. Wang, P. Kim, S. Habib, R. Baron, Y. Conley, and M. Gorin, “Retinal Structure in Pre-Clinical Age-Related Macular Degeneration,” Curr. Eye Res. 43(3), 376–382 (2018).
[Crossref] [PubMed]

E. Pilotto, L. Frizziero, A. R. Daniele, E. Convento, E. Longhin, F. Guidolin, R. Parrozzani, F. Cavarzeran, and E. Midena, “Early OCT angiography changes of type 1 CNV in exudative AMD treated with anti-VEGF,” Br. J. Ophthalmol. 2018, 311752 (2018).
[Crossref] [PubMed]

2017 (6)

Q. Liu, S. Chen, B. Soetikno, W. Liu, S. Tong, and H. Zhang, “Monitoring acute stroke in mouse model using laser speckle imaging-guided visible-light optical coherence tomography,” IEEE Trans. Biomed. Eng. 65, 2136 (2017).
[PubMed]

W. Choi, N. K. Waheed, E. M. Moult, M. Adhi, B. Lee, T. De Carlo, V. Jayaraman, C. R. Baumal, J. S. Duker, and J. G. Fujimoto, “Ultrahigh Speed Swept Source Optical Coherence Tomography Angiography of Retinal and Choriocapillaris Alterations in Diabetic Patients with and without Retinopathy,” Retina 37(1), 11–21 (2017).
[Crossref] [PubMed]

M. Battaglia Parodi, M. V. Cicinelli, A. Rabiolo, L. Pierro, M. Gagliardi, G. Bolognesi, and F. Bandello, “Vessel density analysis in patients with retinitis pigmentosa by means of optical coherence tomography angiography,” Br. J. Ophthalmol. 101(4), 428–432 (2017).
[Crossref] [PubMed]

S. Rösch, C. Aretzweiler, F. Müller, and P. Walter, “Evaluation of Retinal Function and Morphology of the Pink-Eyed Royal College of Surgeons (RCS) Rat: A Comparative Study of in Vivo and in Vitro Methods,” Curr. Eye Res. 42(2), 273–281 (2017).
[Crossref] [PubMed]

R. C. Ryals, M. D. Andrews, S. Datta, A. S. Coyner, C. M. Fischer, Y. Wen, M. E. Pennesi, and T. J. McGill, “Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence Tomography,” Invest. Ophthalmol. Vis. Sci. 58(3), 1378–1386 (2017).
[Crossref] [PubMed]

C. L. Chen and R. K. Wang, “Optical coherence tomography based angiography [Invited],” Biomed. Opt. Express 8(2), 1056–1082 (2017).
[Crossref] [PubMed]

2016 (4)

W. Yuan, J. Mavadia-Shukla, J. Xi, W. Liang, X. Yu, S. Yu, and X. Li, “Optimal operational conditions for supercontinuum-based ultrahigh-resolution endoscopic OCT imaging,” Opt. Lett. 41(2), 250–253 (2016).
[Crossref] [PubMed]

S. Fialová, M. Augustin, M. Glösmann, T. Himmel, S. Rauscher, M. Gröger, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Polarization properties of single layers in the posterior eyes of mice and rats investigated using high resolution polarization sensitive optical coherence tomography,” Biomed. Opt. Express 7(4), 1479–1495 (2016).
[Crossref] [PubMed]

H. Liu, J. Tang, Y. Du, A. Saadane, D. Tonade, I. Samuels, A. Veenstra, K. Palczewski, and T. S. Kern, “Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes,” Invest. Ophthalmol. Vis. Sci. 57(10), 4272–4281 (2016).
[Crossref] [PubMed]

M. Augustin, S. Fialová, T. Himmel, M. Glösmann, T. Lengheimer, D. J. Harper, R. Plasenzotti, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Multi-Functional OCT Enables Longitudinal Study of Retinal Changes in a VLDLR Knockout Mouse Model,” PLoS One 11(10), e0164419 (2016).
[Crossref] [PubMed]

2015 (3)

C. Schütze, M. Wedl, B. Baumann, M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Progression of retinal pigment epithelial atrophy in antiangiogenic therapy of neovascular age-related macular degeneration,” Am. J. Ophthalmol. 159(6), 1100–1114 (2015).
[Crossref] [PubMed]

J. Yi, W. Liu, S. Chen, V. Backman, N. Sheibani, C. M. Sorenson, A. A. Fawzi, R. A. Linsenmeier, and H. F. Zhang, “Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation,” Light Sci. Appl. 4(9), e334 (2015).
[Crossref] [PubMed]

S. P. Chong, C. W. Merkle, C. Leahy, H. Radhakrishnan, and V. J. Srinivasan, “Quantitative microvascular hemoglobin mapping using visible light spectroscopic Optical Coherence Tomography,” Biomed. Opt. Express 6(4), 1429–1450 (2015).
[Crossref] [PubMed]

2014 (4)

J. Yi, S. Chen, V. Backman, and H. F. Zhang, “In vivo functional microangiography by visible-light optical coherence tomography,” Biomed. Opt. Express 5(10), 3603–3612 (2014).
[Crossref] [PubMed]

J. Lammer, M. Bolz, B. Baumann, M. Pircher, B. Gerendas, F. Schlanitz, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Detection and analysis of hard exudates by polarization-sensitive optical coherence tomography in patients with diabetic maculopathy,” Invest. Ophthalmol. Vis. Sci. 55(3), 1564–1571 (2014).
[Crossref] [PubMed]

E. L. Fletcher, A. I. Jobling, U. Greferath, S. A. Mills, M. Waugh, T. Ho, R. U. de Iongh, J. A. Phipps, and K. A. Vessey, “Studying age-related macular degeneration using animal models,” Optom. Vis. Sci. 91(8), 878–886 (2014).
[Crossref] [PubMed]

Y. Feng, Y. Wang, Z. Yang, L. Wu, S. Hoffmann, T. Wieland, N. Gretz, and H. P. Hammes, “Chronic hyperglycemia inhibits vasoregression in a transgenic model of retinal degeneration,” Acta Diabetol. 51(2), 211–218 (2014).
[Crossref] [PubMed]

2013 (2)

2012 (1)

J. Dwelle, S. Liu, B. Wang, A. McElroy, D. Ho, M. K. Markey, T. Milner, and H. G. Rylander, “Thickness, phase retardation, birefringence, and reflectance of the retinal nerve fiber layer in normal and glaucomatous non-human primates,” Invest. Ophthalmol. Vis. Sci. 53(8), 4380–4395 (2012).
[Crossref] [PubMed]

2011 (3)

M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Polarization sensitive optical coherence tomography in the human eye,” Prog. Retin. Eye Res. 30(6), 431–451 (2011).
[Crossref] [PubMed]

H. Wang, A. J. Black, J. Zhu, T. W. Stigen, M. K. Al-Qaisi, T. I. Netoff, A. Abosch, and T. Akkin, “Reconstructing micrometer-scale fiber pathways in the brain: multi-contrast optical coherence tomography based tractography,” Neuroimage 58(4), 984–992 (2011).
[Crossref] [PubMed]

J. Lee, V. Srinivasan, H. Radhakrishnan, and D. A. Boas, “Motion correction for phase-resolved dynamic optical coherence tomography imaging of rodent cerebral cortex,” Opt. Express 19(22), 21258–21270 (2011).
[Crossref] [PubMed]

2008 (1)

E. Vecino, “[Animal models in the study of the glaucoma: past, present and future],” Arch. Soc. Esp. Oftalmol. 83(9), 517–519 (2008).
[Crossref] [PubMed]

2007 (3)

S. P. Daiger, S. J. Bowne, and L. S. Sullivan, “Perspective on genes and mutations causing retinitis pigmentosa,” Arch. Ophthalmol. 125(2), 151–158 (2007).
[Crossref] [PubMed]

M. Friedlander, “Fibrosis and diseases of the eye,” J. Clin. Invest. 117(3), 576–586 (2007).
[Crossref] [PubMed]

W. C. Kuo, N. K. Chou, C. Chou, C. M. Lai, H. J. Huang, S. S. Wang, and J. J. Shyu, “Polarization-sensitive optical coherence tomography for imaging human atherosclerosis,” Appl. Opt. 46(13), 2520–2527 (2007).
[Crossref] [PubMed]

2006 (2)

H. J. Zambarakji, D. J. Keegan, T. M. Holmes, A. S. Halfyard, M. P. Villegas-Perez, D. G. Charteris, F. W. Fitzke, J. Greenwood, and R. D. Lund, “High resolution imaging of fluorescein patterns in RCS rat retinae and their direct correlation with histology,” Exp. Eye Res. 82(1), 164–171 (2006).
[Crossref] [PubMed]

T. E. de Gooyer, K. A. Stevenson, P. Humphries, D. A. Simpson, T. A. Gardiner, and A. W. Stitt, “Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration,” Invest. Ophthalmol. Vis. Sci. 47(12), 5561–5568 (2006).
[Crossref] [PubMed]

2005 (2)

B. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. Tearney, B. Bouma, and J. de Boer, “Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 microm,” Opt. Express 13(11), 3931–3944 (2005).
[Crossref] [PubMed]

U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, “Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases,” Invest. Ophthalmol. Vis. Sci. 46(9), 3393–3402 (2005).
[Crossref] [PubMed]

2003 (1)

2002 (2)

2000 (2)

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

J. S. Penn, S. Li, and M. I. Naash, “Ambient hypoxia reverses retinal vascular attenuation in a transgenic mouse model of autosomal dominant retinitis pigmentosa,” Invest. Ophthalmol. Vis. Sci. 41(12), 4007–4013 (2000).
[PubMed]

1998 (1)

A. H. Milam, Z. Y. Li, and R. N. Fariss, “Histopathology of the human retina in retinitis pigmentosa,” Prog. Retin. Eye Res. 17(2), 175–205 (1998).
[PubMed]

1991 (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

1981 (1)

1962 (1)

J. E. Dowling and R. L. Sidman, “Inherited retinal dystrophy in the rat,” J. Cell Biol. 14(1), 73–109 (1962).
[Crossref] [PubMed]

Abitbol, M. M.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Abosch, A.

H. Wang, A. J. Black, J. Zhu, T. W. Stigen, M. K. Al-Qaisi, T. I. Netoff, A. Abosch, and T. Akkin, “Reconstructing micrometer-scale fiber pathways in the brain: multi-contrast optical coherence tomography based tractography,” Neuroimage 58(4), 984–992 (2011).
[Crossref] [PubMed]

Adhi, M.

W. Choi, N. K. Waheed, E. M. Moult, M. Adhi, B. Lee, T. De Carlo, V. Jayaraman, C. R. Baumal, J. S. Duker, and J. G. Fujimoto, “Ultrahigh Speed Swept Source Optical Coherence Tomography Angiography of Retinal and Choriocapillaris Alterations in Diabetic Patients with and without Retinopathy,” Retina 37(1), 11–21 (2017).
[Crossref] [PubMed]

Ahlers, C.

U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, “Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases,” Invest. Ophthalmol. Vis. Sci. 46(9), 3393–3402 (2005).
[Crossref] [PubMed]

Akkin, T.

H. Wang, A. J. Black, J. Zhu, T. W. Stigen, M. K. Al-Qaisi, T. I. Netoff, A. Abosch, and T. Akkin, “Reconstructing micrometer-scale fiber pathways in the brain: multi-contrast optical coherence tomography based tractography,” Neuroimage 58(4), 984–992 (2011).
[Crossref] [PubMed]

Al-Qaisi, M. K.

H. Wang, A. J. Black, J. Zhu, T. W. Stigen, M. K. Al-Qaisi, T. I. Netoff, A. Abosch, and T. Akkin, “Reconstructing micrometer-scale fiber pathways in the brain: multi-contrast optical coherence tomography based tractography,” Neuroimage 58(4), 984–992 (2011).
[Crossref] [PubMed]

Andrews, M. D.

R. C. Ryals, M. D. Andrews, S. Datta, A. S. Coyner, C. M. Fischer, Y. Wen, M. E. Pennesi, and T. J. McGill, “Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence Tomography,” Invest. Ophthalmol. Vis. Sci. 58(3), 1378–1386 (2017).
[Crossref] [PubMed]

Aretzweiler, C.

S. Rösch, C. Aretzweiler, F. Müller, and P. Walter, “Evaluation of Retinal Function and Morphology of the Pink-Eyed Royal College of Surgeons (RCS) Rat: A Comparative Study of in Vivo and in Vitro Methods,” Curr. Eye Res. 42(2), 273–281 (2017).
[Crossref] [PubMed]

Augustin, M.

M. Augustin, S. Fialová, T. Himmel, M. Glösmann, T. Lengheimer, D. J. Harper, R. Plasenzotti, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Multi-Functional OCT Enables Longitudinal Study of Retinal Changes in a VLDLR Knockout Mouse Model,” PLoS One 11(10), e0164419 (2016).
[Crossref] [PubMed]

S. Fialová, M. Augustin, M. Glösmann, T. Himmel, S. Rauscher, M. Gröger, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Polarization properties of single layers in the posterior eyes of mice and rats investigated using high resolution polarization sensitive optical coherence tomography,” Biomed. Opt. Express 7(4), 1479–1495 (2016).
[Crossref] [PubMed]

Backman, V.

J. Yi, W. Liu, S. Chen, V. Backman, N. Sheibani, C. M. Sorenson, A. A. Fawzi, R. A. Linsenmeier, and H. F. Zhang, “Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation,” Light Sci. Appl. 4(9), e334 (2015).
[Crossref] [PubMed]

J. Yi, S. Chen, V. Backman, and H. F. Zhang, “In vivo functional microangiography by visible-light optical coherence tomography,” Biomed. Opt. Express 5(10), 3603–3612 (2014).
[Crossref] [PubMed]

Bandello, F.

M. Battaglia Parodi, M. V. Cicinelli, A. Rabiolo, L. Pierro, M. Gagliardi, G. Bolognesi, and F. Bandello, “Vessel density analysis in patients with retinitis pigmentosa by means of optical coherence tomography angiography,” Br. J. Ophthalmol. 101(4), 428–432 (2017).
[Crossref] [PubMed]

Baron, R.

S. Nusinowitz, Y. Wang, P. Kim, S. Habib, R. Baron, Y. Conley, and M. Gorin, “Retinal Structure in Pre-Clinical Age-Related Macular Degeneration,” Curr. Eye Res. 43(3), 376–382 (2018).
[Crossref] [PubMed]

Battaglia Parodi, M.

M. Battaglia Parodi, M. V. Cicinelli, A. Rabiolo, L. Pierro, M. Gagliardi, G. Bolognesi, and F. Bandello, “Vessel density analysis in patients with retinitis pigmentosa by means of optical coherence tomography angiography,” Br. J. Ophthalmol. 101(4), 428–432 (2017).
[Crossref] [PubMed]

Baumal, C. R.

W. Choi, N. K. Waheed, E. M. Moult, M. Adhi, B. Lee, T. De Carlo, V. Jayaraman, C. R. Baumal, J. S. Duker, and J. G. Fujimoto, “Ultrahigh Speed Swept Source Optical Coherence Tomography Angiography of Retinal and Choriocapillaris Alterations in Diabetic Patients with and without Retinopathy,” Retina 37(1), 11–21 (2017).
[Crossref] [PubMed]

Baumann, B.

M. Augustin, S. Fialová, T. Himmel, M. Glösmann, T. Lengheimer, D. J. Harper, R. Plasenzotti, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Multi-Functional OCT Enables Longitudinal Study of Retinal Changes in a VLDLR Knockout Mouse Model,” PLoS One 11(10), e0164419 (2016).
[Crossref] [PubMed]

S. Fialová, M. Augustin, M. Glösmann, T. Himmel, S. Rauscher, M. Gröger, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Polarization properties of single layers in the posterior eyes of mice and rats investigated using high resolution polarization sensitive optical coherence tomography,” Biomed. Opt. Express 7(4), 1479–1495 (2016).
[Crossref] [PubMed]

C. Schütze, M. Wedl, B. Baumann, M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Progression of retinal pigment epithelial atrophy in antiangiogenic therapy of neovascular age-related macular degeneration,” Am. J. Ophthalmol. 159(6), 1100–1114 (2015).
[Crossref] [PubMed]

J. Lammer, M. Bolz, B. Baumann, M. Pircher, B. Gerendas, F. Schlanitz, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Detection and analysis of hard exudates by polarization-sensitive optical coherence tomography in patients with diabetic maculopathy,” Invest. Ophthalmol. Vis. Sci. 55(3), 1564–1571 (2014).
[Crossref] [PubMed]

Bihoreau, M. T.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Black, A. J.

H. Wang, A. J. Black, J. Zhu, T. W. Stigen, M. K. Al-Qaisi, T. I. Netoff, A. Abosch, and T. Akkin, “Reconstructing micrometer-scale fiber pathways in the brain: multi-contrast optical coherence tomography based tractography,” Neuroimage 58(4), 984–992 (2011).
[Crossref] [PubMed]

Boas, D. A.

Bolognesi, G.

M. Battaglia Parodi, M. V. Cicinelli, A. Rabiolo, L. Pierro, M. Gagliardi, G. Bolognesi, and F. Bandello, “Vessel density analysis in patients with retinitis pigmentosa by means of optical coherence tomography angiography,” Br. J. Ophthalmol. 101(4), 428–432 (2017).
[Crossref] [PubMed]

Bolz, M.

J. Lammer, M. Bolz, B. Baumann, M. Pircher, B. Gerendas, F. Schlanitz, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Detection and analysis of hard exudates by polarization-sensitive optical coherence tomography in patients with diabetic maculopathy,” Invest. Ophthalmol. Vis. Sci. 55(3), 1564–1571 (2014).
[Crossref] [PubMed]

Bonnel, S.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Bouma, B.

Bowne, S. J.

S. P. Daiger, S. J. Bowne, and L. S. Sullivan, “Perspective on genes and mutations causing retinitis pigmentosa,” Arch. Ophthalmol. 125(2), 151–158 (2007).
[Crossref] [PubMed]

Cavarzeran, F.

E. Pilotto, L. Frizziero, A. R. Daniele, E. Convento, E. Longhin, F. Guidolin, R. Parrozzani, F. Cavarzeran, and E. Midena, “Early OCT angiography changes of type 1 CNV in exudative AMD treated with anti-VEGF,” Br. J. Ophthalmol. 2018, 311752 (2018).
[Crossref] [PubMed]

Cense, B.

Chang, C. Y.

Chang, W.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Charteris, D. G.

H. J. Zambarakji, D. J. Keegan, T. M. Holmes, A. S. Halfyard, M. P. Villegas-Perez, D. G. Charteris, F. W. Fitzke, J. Greenwood, and R. D. Lund, “High resolution imaging of fluorescein patterns in RCS rat retinae and their direct correlation with histology,” Exp. Eye Res. 82(1), 164–171 (2006).
[Crossref] [PubMed]

Chen, C. L.

Chen, S.

Q. Liu, S. Chen, B. Soetikno, W. Liu, S. Tong, and H. Zhang, “Monitoring acute stroke in mouse model using laser speckle imaging-guided visible-light optical coherence tomography,” IEEE Trans. Biomed. Eng. 65, 2136 (2017).
[PubMed]

J. Yi, W. Liu, S. Chen, V. Backman, N. Sheibani, C. M. Sorenson, A. A. Fawzi, R. A. Linsenmeier, and H. F. Zhang, “Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation,” Light Sci. Appl. 4(9), e334 (2015).
[Crossref] [PubMed]

J. Yi, S. Chen, V. Backman, and H. F. Zhang, “In vivo functional microangiography by visible-light optical coherence tomography,” Biomed. Opt. Express 5(10), 3603–3612 (2014).
[Crossref] [PubMed]

Chen, Z.

Choi, W.

W. Choi, N. K. Waheed, E. M. Moult, M. Adhi, B. Lee, T. De Carlo, V. Jayaraman, C. R. Baumal, J. S. Duker, and J. G. Fujimoto, “Ultrahigh Speed Swept Source Optical Coherence Tomography Angiography of Retinal and Choriocapillaris Alterations in Diabetic Patients with and without Retinopathy,” Retina 37(1), 11–21 (2017).
[Crossref] [PubMed]

Chong, S. P.

Chou, C.

Chou, N. K.

Cicinelli, M. V.

M. Battaglia Parodi, M. V. Cicinelli, A. Rabiolo, L. Pierro, M. Gagliardi, G. Bolognesi, and F. Bandello, “Vessel density analysis in patients with retinitis pigmentosa by means of optical coherence tomography angiography,” Br. J. Ophthalmol. 101(4), 428–432 (2017).
[Crossref] [PubMed]

Conley, Y.

S. Nusinowitz, Y. Wang, P. Kim, S. Habib, R. Baron, Y. Conley, and M. Gorin, “Retinal Structure in Pre-Clinical Age-Related Macular Degeneration,” Curr. Eye Res. 43(3), 376–382 (2018).
[Crossref] [PubMed]

Convento, E.

E. Pilotto, L. Frizziero, A. R. Daniele, E. Convento, E. Longhin, F. Guidolin, R. Parrozzani, F. Cavarzeran, and E. Midena, “Early OCT angiography changes of type 1 CNV in exudative AMD treated with anti-VEGF,” Br. J. Ophthalmol. 2018, 311752 (2018).
[Crossref] [PubMed]

Coyner, A. S.

R. C. Ryals, M. D. Andrews, S. Datta, A. S. Coyner, C. M. Fischer, Y. Wen, M. E. Pennesi, and T. J. McGill, “Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence Tomography,” Invest. Ophthalmol. Vis. Sci. 58(3), 1378–1386 (2017).
[Crossref] [PubMed]

Daiger, S. P.

S. P. Daiger, S. J. Bowne, and L. S. Sullivan, “Perspective on genes and mutations causing retinitis pigmentosa,” Arch. Ophthalmol. 125(2), 151–158 (2007).
[Crossref] [PubMed]

Daniele, A. R.

E. Pilotto, L. Frizziero, A. R. Daniele, E. Convento, E. Longhin, F. Guidolin, R. Parrozzani, F. Cavarzeran, and E. Midena, “Early OCT angiography changes of type 1 CNV in exudative AMD treated with anti-VEGF,” Br. J. Ophthalmol. 2018, 311752 (2018).
[Crossref] [PubMed]

Datta, S.

R. C. Ryals, M. D. Andrews, S. Datta, A. S. Coyner, C. M. Fischer, Y. Wen, M. E. Pennesi, and T. J. McGill, “Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence Tomography,” Invest. Ophthalmol. Vis. Sci. 58(3), 1378–1386 (2017).
[Crossref] [PubMed]

de Boer, J.

de Boer, J. F.

De Carlo, T.

W. Choi, N. K. Waheed, E. M. Moult, M. Adhi, B. Lee, T. De Carlo, V. Jayaraman, C. R. Baumal, J. S. Duker, and J. G. Fujimoto, “Ultrahigh Speed Swept Source Optical Coherence Tomography Angiography of Retinal and Choriocapillaris Alterations in Diabetic Patients with and without Retinopathy,” Retina 37(1), 11–21 (2017).
[Crossref] [PubMed]

de Gooyer, T. E.

T. E. de Gooyer, K. A. Stevenson, P. Humphries, D. A. Simpson, T. A. Gardiner, and A. W. Stitt, “Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration,” Invest. Ophthalmol. Vis. Sci. 47(12), 5561–5568 (2006).
[Crossref] [PubMed]

de Iongh, R. U.

E. L. Fletcher, A. I. Jobling, U. Greferath, S. A. Mills, M. Waugh, T. Ho, R. U. de Iongh, J. A. Phipps, and K. A. Vessey, “Studying age-related macular degeneration using animal models,” Optom. Vis. Sci. 91(8), 878–886 (2014).
[Crossref] [PubMed]

Ding, Z.

Dowling, J. E.

J. E. Dowling and R. L. Sidman, “Inherited retinal dystrophy in the rat,” J. Cell Biol. 14(1), 73–109 (1962).
[Crossref] [PubMed]

Drexler, W.

U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, “Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases,” Invest. Ophthalmol. Vis. Sci. 46(9), 3393–3402 (2005).
[Crossref] [PubMed]

Du, Y.

H. Liu, J. Tang, Y. Du, A. Saadane, D. Tonade, I. Samuels, A. Veenstra, K. Palczewski, and T. S. Kern, “Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes,” Invest. Ophthalmol. Vis. Sci. 57(10), 4272–4281 (2016).
[Crossref] [PubMed]

Duan, L.

Dufier, J. L.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Dufour, E. M.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Duker, J. S.

W. Choi, N. K. Waheed, E. M. Moult, M. Adhi, B. Lee, T. De Carlo, V. Jayaraman, C. R. Baumal, J. S. Duker, and J. G. Fujimoto, “Ultrahigh Speed Swept Source Optical Coherence Tomography Angiography of Retinal and Choriocapillaris Alterations in Diabetic Patients with and without Retinopathy,” Retina 37(1), 11–21 (2017).
[Crossref] [PubMed]

Dwelle, J.

J. Dwelle, S. Liu, B. Wang, A. McElroy, D. Ho, M. K. Markey, T. Milner, and H. G. Rylander, “Thickness, phase retardation, birefringence, and reflectance of the retinal nerve fiber layer in normal and glaucomatous non-human primates,” Invest. Ophthalmol. Vis. Sci. 53(8), 4380–4395 (2012).
[Crossref] [PubMed]

Eickhoff, W.

et,

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Fariss, R. N.

A. H. Milam, Z. Y. Li, and R. N. Fariss, “Histopathology of the human retina in retinitis pigmentosa,” Prog. Retin. Eye Res. 17(2), 175–205 (1998).
[PubMed]

Fawzi, A. A.

J. Yi, W. Liu, S. Chen, V. Backman, N. Sheibani, C. M. Sorenson, A. A. Fawzi, R. A. Linsenmeier, and H. F. Zhang, “Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation,” Light Sci. Appl. 4(9), e334 (2015).
[Crossref] [PubMed]

Feng, Y.

Y. Feng, Y. Wang, Z. Yang, L. Wu, S. Hoffmann, T. Wieland, N. Gretz, and H. P. Hammes, “Chronic hyperglycemia inhibits vasoregression in a transgenic model of retinal degeneration,” Acta Diabetol. 51(2), 211–218 (2014).
[Crossref] [PubMed]

Fercher, A. F.

U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, “Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases,” Invest. Ophthalmol. Vis. Sci. 46(9), 3393–3402 (2005).
[Crossref] [PubMed]

Fialová, S.

M. Augustin, S. Fialová, T. Himmel, M. Glösmann, T. Lengheimer, D. J. Harper, R. Plasenzotti, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Multi-Functional OCT Enables Longitudinal Study of Retinal Changes in a VLDLR Knockout Mouse Model,” PLoS One 11(10), e0164419 (2016).
[Crossref] [PubMed]

S. Fialová, M. Augustin, M. Glösmann, T. Himmel, S. Rauscher, M. Gröger, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Polarization properties of single layers in the posterior eyes of mice and rats investigated using high resolution polarization sensitive optical coherence tomography,” Biomed. Opt. Express 7(4), 1479–1495 (2016).
[Crossref] [PubMed]

Fischer, C. M.

R. C. Ryals, M. D. Andrews, S. Datta, A. S. Coyner, C. M. Fischer, Y. Wen, M. E. Pennesi, and T. J. McGill, “Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence Tomography,” Invest. Ophthalmol. Vis. Sci. 58(3), 1378–1386 (2017).
[Crossref] [PubMed]

Fitzke, F. W.

H. J. Zambarakji, D. J. Keegan, T. M. Holmes, A. S. Halfyard, M. P. Villegas-Perez, D. G. Charteris, F. W. Fitzke, J. Greenwood, and R. D. Lund, “High resolution imaging of fluorescein patterns in RCS rat retinae and their direct correlation with histology,” Exp. Eye Res. 82(1), 164–171 (2006).
[Crossref] [PubMed]

Fletcher, E. L.

E. L. Fletcher, A. I. Jobling, U. Greferath, S. A. Mills, M. Waugh, T. Ho, R. U. de Iongh, J. A. Phipps, and K. A. Vessey, “Studying age-related macular degeneration using animal models,” Optom. Vis. Sci. 91(8), 878–886 (2014).
[Crossref] [PubMed]

Flotte, T.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Friedlander, M.

M. Friedlander, “Fibrosis and diseases of the eye,” J. Clin. Invest. 117(3), 576–586 (2007).
[Crossref] [PubMed]

Frizziero, L.

E. Pilotto, L. Frizziero, A. R. Daniele, E. Convento, E. Longhin, F. Guidolin, R. Parrozzani, F. Cavarzeran, and E. Midena, “Early OCT angiography changes of type 1 CNV in exudative AMD treated with anti-VEGF,” Br. J. Ophthalmol. 2018, 311752 (2018).
[Crossref] [PubMed]

Fujimoto, J. G.

W. Choi, N. K. Waheed, E. M. Moult, M. Adhi, B. Lee, T. De Carlo, V. Jayaraman, C. R. Baumal, J. S. Duker, and J. G. Fujimoto, “Ultrahigh Speed Swept Source Optical Coherence Tomography Angiography of Retinal and Choriocapillaris Alterations in Diabetic Patients with and without Retinopathy,” Retina 37(1), 11–21 (2017).
[Crossref] [PubMed]

Gagliardi, M.

M. Battaglia Parodi, M. V. Cicinelli, A. Rabiolo, L. Pierro, M. Gagliardi, G. Bolognesi, and F. Bandello, “Vessel density analysis in patients with retinitis pigmentosa by means of optical coherence tomography angiography,” Br. J. Ophthalmol. 101(4), 428–432 (2017).
[Crossref] [PubMed]

Gardiner, T. A.

T. E. de Gooyer, K. A. Stevenson, P. Humphries, D. A. Simpson, T. A. Gardiner, and A. W. Stitt, “Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration,” Invest. Ophthalmol. Vis. Sci. 47(12), 5561–5568 (2006).
[Crossref] [PubMed]

Gerendas, B.

J. Lammer, M. Bolz, B. Baumann, M. Pircher, B. Gerendas, F. Schlanitz, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Detection and analysis of hard exudates by polarization-sensitive optical coherence tomography in patients with diabetic maculopathy,” Invest. Ophthalmol. Vis. Sci. 55(3), 1564–1571 (2014).
[Crossref] [PubMed]

Glösmann, M.

M. Augustin, S. Fialová, T. Himmel, M. Glösmann, T. Lengheimer, D. J. Harper, R. Plasenzotti, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Multi-Functional OCT Enables Longitudinal Study of Retinal Changes in a VLDLR Knockout Mouse Model,” PLoS One 11(10), e0164419 (2016).
[Crossref] [PubMed]

S. Fialová, M. Augustin, M. Glösmann, T. Himmel, S. Rauscher, M. Gröger, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Polarization properties of single layers in the posterior eyes of mice and rats investigated using high resolution polarization sensitive optical coherence tomography,” Biomed. Opt. Express 7(4), 1479–1495 (2016).
[Crossref] [PubMed]

Gogat, K.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Gorin, M.

S. Nusinowitz, Y. Wang, P. Kim, S. Habib, R. Baron, Y. Conley, and M. Gorin, “Retinal Structure in Pre-Clinical Age-Related Macular Degeneration,” Curr. Eye Res. 43(3), 376–382 (2018).
[Crossref] [PubMed]

Greenwood, J.

H. J. Zambarakji, D. J. Keegan, T. M. Holmes, A. S. Halfyard, M. P. Villegas-Perez, D. G. Charteris, F. W. Fitzke, J. Greenwood, and R. D. Lund, “High resolution imaging of fluorescein patterns in RCS rat retinae and their direct correlation with histology,” Exp. Eye Res. 82(1), 164–171 (2006).
[Crossref] [PubMed]

Greferath, U.

E. L. Fletcher, A. I. Jobling, U. Greferath, S. A. Mills, M. Waugh, T. Ho, R. U. de Iongh, J. A. Phipps, and K. A. Vessey, “Studying age-related macular degeneration using animal models,” Optom. Vis. Sci. 91(8), 878–886 (2014).
[Crossref] [PubMed]

Gregory, K.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Gretz, N.

Y. Feng, Y. Wang, Z. Yang, L. Wu, S. Hoffmann, T. Wieland, N. Gretz, and H. P. Hammes, “Chronic hyperglycemia inhibits vasoregression in a transgenic model of retinal degeneration,” Acta Diabetol. 51(2), 211–218 (2014).
[Crossref] [PubMed]

Gröger, M.

Guidolin, F.

E. Pilotto, L. Frizziero, A. R. Daniele, E. Convento, E. Longhin, F. Guidolin, R. Parrozzani, F. Cavarzeran, and E. Midena, “Early OCT angiography changes of type 1 CNV in exudative AMD treated with anti-VEGF,” Br. J. Ophthalmol. 2018, 311752 (2018).
[Crossref] [PubMed]

Habib, S.

S. Nusinowitz, Y. Wang, P. Kim, S. Habib, R. Baron, Y. Conley, and M. Gorin, “Retinal Structure in Pre-Clinical Age-Related Macular Degeneration,” Curr. Eye Res. 43(3), 376–382 (2018).
[Crossref] [PubMed]

Halfyard, A. S.

H. J. Zambarakji, D. J. Keegan, T. M. Holmes, A. S. Halfyard, M. P. Villegas-Perez, D. G. Charteris, F. W. Fitzke, J. Greenwood, and R. D. Lund, “High resolution imaging of fluorescein patterns in RCS rat retinae and their direct correlation with histology,” Exp. Eye Res. 82(1), 164–171 (2006).
[Crossref] [PubMed]

Hammes, H. P.

Y. Feng, Y. Wang, Z. Yang, L. Wu, S. Hoffmann, T. Wieland, N. Gretz, and H. P. Hammes, “Chronic hyperglycemia inhibits vasoregression in a transgenic model of retinal degeneration,” Acta Diabetol. 51(2), 211–218 (2014).
[Crossref] [PubMed]

Harper, D. J.

M. Augustin, S. Fialová, T. Himmel, M. Glösmann, T. Lengheimer, D. J. Harper, R. Plasenzotti, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Multi-Functional OCT Enables Longitudinal Study of Retinal Changes in a VLDLR Knockout Mouse Model,” PLoS One 11(10), e0164419 (2016).
[Crossref] [PubMed]

Hee, M. R.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Hermann, B.

U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, “Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases,” Invest. Ophthalmol. Vis. Sci. 46(9), 3393–3402 (2005).
[Crossref] [PubMed]

Himmel, T.

M. Augustin, S. Fialová, T. Himmel, M. Glösmann, T. Lengheimer, D. J. Harper, R. Plasenzotti, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Multi-Functional OCT Enables Longitudinal Study of Retinal Changes in a VLDLR Knockout Mouse Model,” PLoS One 11(10), e0164419 (2016).
[Crossref] [PubMed]

S. Fialová, M. Augustin, M. Glösmann, T. Himmel, S. Rauscher, M. Gröger, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Polarization properties of single layers in the posterior eyes of mice and rats investigated using high resolution polarization sensitive optical coherence tomography,” Biomed. Opt. Express 7(4), 1479–1495 (2016).
[Crossref] [PubMed]

Hitzenberger, C. K.

S. Fialová, M. Augustin, M. Glösmann, T. Himmel, S. Rauscher, M. Gröger, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Polarization properties of single layers in the posterior eyes of mice and rats investigated using high resolution polarization sensitive optical coherence tomography,” Biomed. Opt. Express 7(4), 1479–1495 (2016).
[Crossref] [PubMed]

M. Augustin, S. Fialová, T. Himmel, M. Glösmann, T. Lengheimer, D. J. Harper, R. Plasenzotti, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Multi-Functional OCT Enables Longitudinal Study of Retinal Changes in a VLDLR Knockout Mouse Model,” PLoS One 11(10), e0164419 (2016).
[Crossref] [PubMed]

C. Schütze, M. Wedl, B. Baumann, M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Progression of retinal pigment epithelial atrophy in antiangiogenic therapy of neovascular age-related macular degeneration,” Am. J. Ophthalmol. 159(6), 1100–1114 (2015).
[Crossref] [PubMed]

J. Lammer, M. Bolz, B. Baumann, M. Pircher, B. Gerendas, F. Schlanitz, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Detection and analysis of hard exudates by polarization-sensitive optical coherence tomography in patients with diabetic maculopathy,” Invest. Ophthalmol. Vis. Sci. 55(3), 1564–1571 (2014).
[Crossref] [PubMed]

M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Polarization sensitive optical coherence tomography in the human eye,” Prog. Retin. Eye Res. 30(6), 431–451 (2011).
[Crossref] [PubMed]

Ho, D.

J. Dwelle, S. Liu, B. Wang, A. McElroy, D. Ho, M. K. Markey, T. Milner, and H. G. Rylander, “Thickness, phase retardation, birefringence, and reflectance of the retinal nerve fiber layer in normal and glaucomatous non-human primates,” Invest. Ophthalmol. Vis. Sci. 53(8), 4380–4395 (2012).
[Crossref] [PubMed]

Ho, T.

E. L. Fletcher, A. I. Jobling, U. Greferath, S. A. Mills, M. Waugh, T. Ho, R. U. de Iongh, J. A. Phipps, and K. A. Vessey, “Studying age-related macular degeneration using animal models,” Optom. Vis. Sci. 91(8), 878–886 (2014).
[Crossref] [PubMed]

Hoffmann, S.

Y. Feng, Y. Wang, Z. Yang, L. Wu, S. Hoffmann, T. Wieland, N. Gretz, and H. P. Hammes, “Chronic hyperglycemia inhibits vasoregression in a transgenic model of retinal degeneration,” Acta Diabetol. 51(2), 211–218 (2014).
[Crossref] [PubMed]

Holmes, T. M.

H. J. Zambarakji, D. J. Keegan, T. M. Holmes, A. S. Halfyard, M. P. Villegas-Perez, D. G. Charteris, F. W. Fitzke, J. Greenwood, and R. D. Lund, “High resolution imaging of fluorescein patterns in RCS rat retinae and their direct correlation with histology,” Exp. Eye Res. 82(1), 164–171 (2006).
[Crossref] [PubMed]

Hong, Y. J.

Huang, D.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Huang, H. J.

Huang, Y. S.

Humphries, P.

T. E. de Gooyer, K. A. Stevenson, P. Humphries, D. A. Simpson, T. A. Gardiner, and A. W. Stitt, “Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration,” Invest. Ophthalmol. Vis. Sci. 47(12), 5561–5568 (2006).
[Crossref] [PubMed]

Hyle Park, B.

Jayaraman, V.

W. Choi, N. K. Waheed, E. M. Moult, M. Adhi, B. Lee, T. De Carlo, V. Jayaraman, C. R. Baumal, J. S. Duker, and J. G. Fujimoto, “Ultrahigh Speed Swept Source Optical Coherence Tomography Angiography of Retinal and Choriocapillaris Alterations in Diabetic Patients with and without Retinopathy,” Retina 37(1), 11–21 (2017).
[Crossref] [PubMed]

Jobling, A. I.

E. L. Fletcher, A. I. Jobling, U. Greferath, S. A. Mills, M. Waugh, T. Ho, R. U. de Iongh, J. A. Phipps, and K. A. Vessey, “Studying age-related macular degeneration using animal models,” Optom. Vis. Sci. 91(8), 878–886 (2014).
[Crossref] [PubMed]

Ju, M. J.

Kawabe, T.

N. Nishizawa, H. Kawagoe, M. Yamanaka, M. Matsushima, K. Mori, and T. Kawabe, “Wavelength Dependence of Ultrahigh-Resolution Optical Coherence Tomography Using Supercontinuum for Biomedical Imaging,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1–15 (2019).
[Crossref]

Kawagoe, H.

N. Nishizawa, H. Kawagoe, M. Yamanaka, M. Matsushima, K. Mori, and T. Kawabe, “Wavelength Dependence of Ultrahigh-Resolution Optical Coherence Tomography Using Supercontinuum for Biomedical Imaging,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1–15 (2019).
[Crossref]

Keegan, D. J.

H. J. Zambarakji, D. J. Keegan, T. M. Holmes, A. S. Halfyard, M. P. Villegas-Perez, D. G. Charteris, F. W. Fitzke, J. Greenwood, and R. D. Lund, “High resolution imaging of fluorescein patterns in RCS rat retinae and their direct correlation with histology,” Exp. Eye Res. 82(1), 164–171 (2006).
[Crossref] [PubMed]

Kern, T. S.

H. Liu, J. Tang, Y. Du, A. Saadane, D. Tonade, I. Samuels, A. Veenstra, K. Palczewski, and T. S. Kern, “Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes,” Invest. Ophthalmol. Vis. Sci. 57(10), 4272–4281 (2016).
[Crossref] [PubMed]

Kim, P.

S. Nusinowitz, Y. Wang, P. Kim, S. Habib, R. Baron, Y. Conley, and M. Gorin, “Retinal Structure in Pre-Clinical Age-Related Macular Degeneration,” Curr. Eye Res. 43(3), 376–382 (2018).
[Crossref] [PubMed]

Kuo, W. C.

Kuo, Y. M.

Kurokawa, K.

Lai, C. M.

Lammer, J.

J. Lammer, M. Bolz, B. Baumann, M. Pircher, B. Gerendas, F. Schlanitz, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Detection and analysis of hard exudates by polarization-sensitive optical coherence tomography in patients with diabetic maculopathy,” Invest. Ophthalmol. Vis. Sci. 55(3), 1564–1571 (2014).
[Crossref] [PubMed]

Lathrop, M.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Leahy, C.

Lee, B.

W. Choi, N. K. Waheed, E. M. Moult, M. Adhi, B. Lee, T. De Carlo, V. Jayaraman, C. R. Baumal, J. S. Duker, and J. G. Fujimoto, “Ultrahigh Speed Swept Source Optical Coherence Tomography Angiography of Retinal and Choriocapillaris Alterations in Diabetic Patients with and without Retinopathy,” Retina 37(1), 11–21 (2017).
[Crossref] [PubMed]

Lee, J.

Leitgeb, R. A.

U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, “Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases,” Invest. Ophthalmol. Vis. Sci. 46(9), 3393–3402 (2005).
[Crossref] [PubMed]

Lengheimer, T.

M. Augustin, S. Fialová, T. Himmel, M. Glösmann, T. Lengheimer, D. J. Harper, R. Plasenzotti, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Multi-Functional OCT Enables Longitudinal Study of Retinal Changes in a VLDLR Knockout Mouse Model,” PLoS One 11(10), e0164419 (2016).
[Crossref] [PubMed]

Li, S.

J. S. Penn, S. Li, and M. I. Naash, “Ambient hypoxia reverses retinal vascular attenuation in a transgenic mouse model of autosomal dominant retinitis pigmentosa,” Invest. Ophthalmol. Vis. Sci. 41(12), 4007–4013 (2000).
[PubMed]

Li, X.

Li, Z. Y.

A. H. Milam, Z. Y. Li, and R. N. Fariss, “Histopathology of the human retina in retinitis pigmentosa,” Prog. Retin. Eye Res. 17(2), 175–205 (1998).
[PubMed]

Liang, W.

Lim, Y.

Lin, C. P.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Linsenmeier, R. A.

J. Yi, W. Liu, S. Chen, V. Backman, N. Sheibani, C. M. Sorenson, A. A. Fawzi, R. A. Linsenmeier, and H. F. Zhang, “Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation,” Light Sci. Appl. 4(9), e334 (2015).
[Crossref] [PubMed]

Liu, H.

H. Liu, J. Tang, Y. Du, A. Saadane, D. Tonade, I. Samuels, A. Veenstra, K. Palczewski, and T. S. Kern, “Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes,” Invest. Ophthalmol. Vis. Sci. 57(10), 4272–4281 (2016).
[Crossref] [PubMed]

Liu, Q.

Q. Liu, S. Chen, B. Soetikno, W. Liu, S. Tong, and H. Zhang, “Monitoring acute stroke in mouse model using laser speckle imaging-guided visible-light optical coherence tomography,” IEEE Trans. Biomed. Eng. 65, 2136 (2017).
[PubMed]

Liu, S.

J. Dwelle, S. Liu, B. Wang, A. McElroy, D. Ho, M. K. Markey, T. Milner, and H. G. Rylander, “Thickness, phase retardation, birefringence, and reflectance of the retinal nerve fiber layer in normal and glaucomatous non-human primates,” Invest. Ophthalmol. Vis. Sci. 53(8), 4380–4395 (2012).
[Crossref] [PubMed]

Liu, W.

Q. Liu, S. Chen, B. Soetikno, W. Liu, S. Tong, and H. Zhang, “Monitoring acute stroke in mouse model using laser speckle imaging-guided visible-light optical coherence tomography,” IEEE Trans. Biomed. Eng. 65, 2136 (2017).
[PubMed]

J. Yi, W. Liu, S. Chen, V. Backman, N. Sheibani, C. M. Sorenson, A. A. Fawzi, R. A. Linsenmeier, and H. F. Zhang, “Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation,” Light Sci. Appl. 4(9), e334 (2015).
[Crossref] [PubMed]

Longhin, E.

E. Pilotto, L. Frizziero, A. R. Daniele, E. Convento, E. Longhin, F. Guidolin, R. Parrozzani, F. Cavarzeran, and E. Midena, “Early OCT angiography changes of type 1 CNV in exudative AMD treated with anti-VEGF,” Br. J. Ophthalmol. 2018, 311752 (2018).
[Crossref] [PubMed]

Lund, R. D.

H. J. Zambarakji, D. J. Keegan, T. M. Holmes, A. S. Halfyard, M. P. Villegas-Perez, D. G. Charteris, F. W. Fitzke, J. Greenwood, and R. D. Lund, “High resolution imaging of fluorescein patterns in RCS rat retinae and their direct correlation with histology,” Exp. Eye Res. 82(1), 164–171 (2006).
[Crossref] [PubMed]

Makita, S.

Marchant, D.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Markey, M. K.

J. Dwelle, S. Liu, B. Wang, A. McElroy, D. Ho, M. K. Markey, T. Milner, and H. G. Rylander, “Thickness, phase retardation, birefringence, and reflectance of the retinal nerve fiber layer in normal and glaucomatous non-human primates,” Invest. Ophthalmol. Vis. Sci. 53(8), 4380–4395 (2012).
[Crossref] [PubMed]

Marsac, C.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Matsushima, M.

N. Nishizawa, H. Kawagoe, M. Yamanaka, M. Matsushima, K. Mori, and T. Kawabe, “Wavelength Dependence of Ultrahigh-Resolution Optical Coherence Tomography Using Supercontinuum for Biomedical Imaging,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1–15 (2019).
[Crossref]

Mavadia-Shukla, J.

McElroy, A.

J. Dwelle, S. Liu, B. Wang, A. McElroy, D. Ho, M. K. Markey, T. Milner, and H. G. Rylander, “Thickness, phase retardation, birefringence, and reflectance of the retinal nerve fiber layer in normal and glaucomatous non-human primates,” Invest. Ophthalmol. Vis. Sci. 53(8), 4380–4395 (2012).
[Crossref] [PubMed]

McGill, T. J.

R. C. Ryals, M. D. Andrews, S. Datta, A. S. Coyner, C. M. Fischer, Y. Wen, M. E. Pennesi, and T. J. McGill, “Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence Tomography,” Invest. Ophthalmol. Vis. Sci. 58(3), 1378–1386 (2017).
[Crossref] [PubMed]

Menasche, M.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Merkle, C. W.

Miao, J.

Michels, S.

U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, “Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases,” Invest. Ophthalmol. Vis. Sci. 46(9), 3393–3402 (2005).
[Crossref] [PubMed]

Midena, E.

E. Pilotto, L. Frizziero, A. R. Daniele, E. Convento, E. Longhin, F. Guidolin, R. Parrozzani, F. Cavarzeran, and E. Midena, “Early OCT angiography changes of type 1 CNV in exudative AMD treated with anti-VEGF,” Br. J. Ophthalmol. 2018, 311752 (2018).
[Crossref] [PubMed]

Milam, A. H.

A. H. Milam, Z. Y. Li, and R. N. Fariss, “Histopathology of the human retina in retinitis pigmentosa,” Prog. Retin. Eye Res. 17(2), 175–205 (1998).
[PubMed]

Mills, S. A.

E. L. Fletcher, A. I. Jobling, U. Greferath, S. A. Mills, M. Waugh, T. Ho, R. U. de Iongh, J. A. Phipps, and K. A. Vessey, “Studying age-related macular degeneration using animal models,” Optom. Vis. Sci. 91(8), 878–886 (2014).
[Crossref] [PubMed]

Milner, T.

J. Dwelle, S. Liu, B. Wang, A. McElroy, D. Ho, M. K. Markey, T. Milner, and H. G. Rylander, “Thickness, phase retardation, birefringence, and reflectance of the retinal nerve fiber layer in normal and glaucomatous non-human primates,” Invest. Ophthalmol. Vis. Sci. 53(8), 4380–4395 (2012).
[Crossref] [PubMed]

Miura, M.

Mori, K.

N. Nishizawa, H. Kawagoe, M. Yamanaka, M. Matsushima, K. Mori, and T. Kawabe, “Wavelength Dependence of Ultrahigh-Resolution Optical Coherence Tomography Using Supercontinuum for Biomedical Imaging,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1–15 (2019).
[Crossref]

Moult, E. M.

W. Choi, N. K. Waheed, E. M. Moult, M. Adhi, B. Lee, T. De Carlo, V. Jayaraman, C. R. Baumal, J. S. Duker, and J. G. Fujimoto, “Ultrahigh Speed Swept Source Optical Coherence Tomography Angiography of Retinal and Choriocapillaris Alterations in Diabetic Patients with and without Retinopathy,” Retina 37(1), 11–21 (2017).
[Crossref] [PubMed]

Mujat, M.

Müller, F.

S. Rösch, C. Aretzweiler, F. Müller, and P. Walter, “Evaluation of Retinal Function and Morphology of the Pink-Eyed Royal College of Surgeons (RCS) Rat: A Comparative Study of in Vivo and in Vitro Methods,” Curr. Eye Res. 42(2), 273–281 (2017).
[Crossref] [PubMed]

Naash, M. I.

J. S. Penn, S. Li, and M. I. Naash, “Ambient hypoxia reverses retinal vascular attenuation in a transgenic mouse model of autosomal dominant retinitis pigmentosa,” Invest. Ophthalmol. Vis. Sci. 41(12), 4007–4013 (2000).
[PubMed]

Nandrot, E.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Nelson, J. S.

Netoff, T. I.

H. Wang, A. J. Black, J. Zhu, T. W. Stigen, M. K. Al-Qaisi, T. I. Netoff, A. Abosch, and T. Akkin, “Reconstructing micrometer-scale fiber pathways in the brain: multi-contrast optical coherence tomography based tractography,” Neuroimage 58(4), 984–992 (2011).
[Crossref] [PubMed]

Nishizawa, N.

N. Nishizawa, H. Kawagoe, M. Yamanaka, M. Matsushima, K. Mori, and T. Kawabe, “Wavelength Dependence of Ultrahigh-Resolution Optical Coherence Tomography Using Supercontinuum for Biomedical Imaging,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1–15 (2019).
[Crossref]

Nusinowitz, S.

S. Nusinowitz, Y. Wang, P. Kim, S. Habib, R. Baron, Y. Conley, and M. Gorin, “Retinal Structure in Pre-Clinical Age-Related Macular Degeneration,” Curr. Eye Res. 43(3), 376–382 (2018).
[Crossref] [PubMed]

Palczewski, K.

H. Liu, J. Tang, Y. Du, A. Saadane, D. Tonade, I. Samuels, A. Veenstra, K. Palczewski, and T. S. Kern, “Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes,” Invest. Ophthalmol. Vis. Sci. 57(10), 4272–4281 (2016).
[Crossref] [PubMed]

Park, B.

Parrozzani, R.

E. Pilotto, L. Frizziero, A. R. Daniele, E. Convento, E. Longhin, F. Guidolin, R. Parrozzani, F. Cavarzeran, and E. Midena, “Early OCT angiography changes of type 1 CNV in exudative AMD treated with anti-VEGF,” Br. J. Ophthalmol. 2018, 311752 (2018).
[Crossref] [PubMed]

Penn, J. S.

J. S. Penn, S. Li, and M. I. Naash, “Ambient hypoxia reverses retinal vascular attenuation in a transgenic mouse model of autosomal dominant retinitis pigmentosa,” Invest. Ophthalmol. Vis. Sci. 41(12), 4007–4013 (2000).
[PubMed]

Pennesi, M. E.

R. C. Ryals, M. D. Andrews, S. Datta, A. S. Coyner, C. M. Fischer, Y. Wen, M. E. Pennesi, and T. J. McGill, “Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence Tomography,” Invest. Ophthalmol. Vis. Sci. 58(3), 1378–1386 (2017).
[Crossref] [PubMed]

Péquignot, M. O.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Phipps, J. A.

E. L. Fletcher, A. I. Jobling, U. Greferath, S. A. Mills, M. Waugh, T. Ho, R. U. de Iongh, J. A. Phipps, and K. A. Vessey, “Studying age-related macular degeneration using animal models,” Optom. Vis. Sci. 91(8), 878–886 (2014).
[Crossref] [PubMed]

Pierce, M.

Pierce, M. C.

Pierro, L.

M. Battaglia Parodi, M. V. Cicinelli, A. Rabiolo, L. Pierro, M. Gagliardi, G. Bolognesi, and F. Bandello, “Vessel density analysis in patients with retinitis pigmentosa by means of optical coherence tomography angiography,” Br. J. Ophthalmol. 101(4), 428–432 (2017).
[Crossref] [PubMed]

Pilotto, E.

E. Pilotto, L. Frizziero, A. R. Daniele, E. Convento, E. Longhin, F. Guidolin, R. Parrozzani, F. Cavarzeran, and E. Midena, “Early OCT angiography changes of type 1 CNV in exudative AMD treated with anti-VEGF,” Br. J. Ophthalmol. 2018, 311752 (2018).
[Crossref] [PubMed]

Pircher, M.

M. Augustin, S. Fialová, T. Himmel, M. Glösmann, T. Lengheimer, D. J. Harper, R. Plasenzotti, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Multi-Functional OCT Enables Longitudinal Study of Retinal Changes in a VLDLR Knockout Mouse Model,” PLoS One 11(10), e0164419 (2016).
[Crossref] [PubMed]

S. Fialová, M. Augustin, M. Glösmann, T. Himmel, S. Rauscher, M. Gröger, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Polarization properties of single layers in the posterior eyes of mice and rats investigated using high resolution polarization sensitive optical coherence tomography,” Biomed. Opt. Express 7(4), 1479–1495 (2016).
[Crossref] [PubMed]

C. Schütze, M. Wedl, B. Baumann, M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Progression of retinal pigment epithelial atrophy in antiangiogenic therapy of neovascular age-related macular degeneration,” Am. J. Ophthalmol. 159(6), 1100–1114 (2015).
[Crossref] [PubMed]

J. Lammer, M. Bolz, B. Baumann, M. Pircher, B. Gerendas, F. Schlanitz, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Detection and analysis of hard exudates by polarization-sensitive optical coherence tomography in patients with diabetic maculopathy,” Invest. Ophthalmol. Vis. Sci. 55(3), 1564–1571 (2014).
[Crossref] [PubMed]

M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Polarization sensitive optical coherence tomography in the human eye,” Prog. Retin. Eye Res. 30(6), 431–451 (2011).
[Crossref] [PubMed]

Plasenzotti, R.

M. Augustin, S. Fialová, T. Himmel, M. Glösmann, T. Lengheimer, D. J. Harper, R. Plasenzotti, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Multi-Functional OCT Enables Longitudinal Study of Retinal Changes in a VLDLR Knockout Mouse Model,” PLoS One 11(10), e0164419 (2016).
[Crossref] [PubMed]

Povazay, B.

U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, “Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases,” Invest. Ophthalmol. Vis. Sci. 46(9), 3393–3402 (2005).
[Crossref] [PubMed]

Provost, A. C.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Puliafito, C. A.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Rabiolo, A.

M. Battaglia Parodi, M. V. Cicinelli, A. Rabiolo, L. Pierro, M. Gagliardi, G. Bolognesi, and F. Bandello, “Vessel density analysis in patients with retinitis pigmentosa by means of optical coherence tomography angiography,” Br. J. Ophthalmol. 101(4), 428–432 (2017).
[Crossref] [PubMed]

Radhakrishnan, H.

Rauscher, S.

Ren, H.

Rösch, S.

S. Rösch, C. Aretzweiler, F. Müller, and P. Walter, “Evaluation of Retinal Function and Morphology of the Pink-Eyed Royal College of Surgeons (RCS) Rat: A Comparative Study of in Vivo and in Vitro Methods,” Curr. Eye Res. 42(2), 273–281 (2017).
[Crossref] [PubMed]

Rouillac, C.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Ryals, R. C.

R. C. Ryals, M. D. Andrews, S. Datta, A. S. Coyner, C. M. Fischer, Y. Wen, M. E. Pennesi, and T. J. McGill, “Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence Tomography,” Invest. Ophthalmol. Vis. Sci. 58(3), 1378–1386 (2017).
[Crossref] [PubMed]

Rylander, H. G.

J. Dwelle, S. Liu, B. Wang, A. McElroy, D. Ho, M. K. Markey, T. Milner, and H. G. Rylander, “Thickness, phase retardation, birefringence, and reflectance of the retinal nerve fiber layer in normal and glaucomatous non-human primates,” Invest. Ophthalmol. Vis. Sci. 53(8), 4380–4395 (2012).
[Crossref] [PubMed]

Saadane, A.

H. Liu, J. Tang, Y. Du, A. Saadane, D. Tonade, I. Samuels, A. Veenstra, K. Palczewski, and T. S. Kern, “Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes,” Invest. Ophthalmol. Vis. Sci. 57(10), 4272–4281 (2016).
[Crossref] [PubMed]

Sacu, S.

U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, “Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases,” Invest. Ophthalmol. Vis. Sci. 46(9), 3393–3402 (2005).
[Crossref] [PubMed]

Samuels, I.

H. Liu, J. Tang, Y. Du, A. Saadane, D. Tonade, I. Samuels, A. Veenstra, K. Palczewski, and T. S. Kern, “Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes,” Invest. Ophthalmol. Vis. Sci. 57(10), 4272–4281 (2016).
[Crossref] [PubMed]

Sattmann, H.

U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, “Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases,” Invest. Ophthalmol. Vis. Sci. 46(9), 3393–3402 (2005).
[Crossref] [PubMed]

Schlanitz, F.

J. Lammer, M. Bolz, B. Baumann, M. Pircher, B. Gerendas, F. Schlanitz, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Detection and analysis of hard exudates by polarization-sensitive optical coherence tomography in patients with diabetic maculopathy,” Invest. Ophthalmol. Vis. Sci. 55(3), 1564–1571 (2014).
[Crossref] [PubMed]

Schmidt-Erfurth, U.

C. Schütze, M. Wedl, B. Baumann, M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Progression of retinal pigment epithelial atrophy in antiangiogenic therapy of neovascular age-related macular degeneration,” Am. J. Ophthalmol. 159(6), 1100–1114 (2015).
[Crossref] [PubMed]

J. Lammer, M. Bolz, B. Baumann, M. Pircher, B. Gerendas, F. Schlanitz, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Detection and analysis of hard exudates by polarization-sensitive optical coherence tomography in patients with diabetic maculopathy,” Invest. Ophthalmol. Vis. Sci. 55(3), 1564–1571 (2014).
[Crossref] [PubMed]

M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Polarization sensitive optical coherence tomography in the human eye,” Prog. Retin. Eye Res. 30(6), 431–451 (2011).
[Crossref] [PubMed]

U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, “Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases,” Invest. Ophthalmol. Vis. Sci. 46(9), 3393–3402 (2005).
[Crossref] [PubMed]

Scholda, C.

U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, “Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases,” Invest. Ophthalmol. Vis. Sci. 46(9), 3393–3402 (2005).
[Crossref] [PubMed]

Schuman, J. S.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Schütze, C.

C. Schütze, M. Wedl, B. Baumann, M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Progression of retinal pigment epithelial atrophy in antiangiogenic therapy of neovascular age-related macular degeneration,” Am. J. Ophthalmol. 159(6), 1100–1114 (2015).
[Crossref] [PubMed]

Sépulchre de Condé, B.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Shaver, C.

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Sheibani, N.

J. Yi, W. Liu, S. Chen, V. Backman, N. Sheibani, C. M. Sorenson, A. A. Fawzi, R. A. Linsenmeier, and H. F. Zhang, “Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation,” Light Sci. Appl. 4(9), e334 (2015).
[Crossref] [PubMed]

Shyu, J. J.

Sidman, R. L.

J. E. Dowling and R. L. Sidman, “Inherited retinal dystrophy in the rat,” J. Cell Biol. 14(1), 73–109 (1962).
[Crossref] [PubMed]

Simpson, D. A.

T. E. de Gooyer, K. A. Stevenson, P. Humphries, D. A. Simpson, T. A. Gardiner, and A. W. Stitt, “Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration,” Invest. Ophthalmol. Vis. Sci. 47(12), 5561–5568 (2006).
[Crossref] [PubMed]

Soetikno, B.

Q. Liu, S. Chen, B. Soetikno, W. Liu, S. Tong, and H. Zhang, “Monitoring acute stroke in mouse model using laser speckle imaging-guided visible-light optical coherence tomography,” IEEE Trans. Biomed. Eng. 65, 2136 (2017).
[PubMed]

Sorenson, C. M.

J. Yi, W. Liu, S. Chen, V. Backman, N. Sheibani, C. M. Sorenson, A. A. Fawzi, R. A. Linsenmeier, and H. F. Zhang, “Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation,” Light Sci. Appl. 4(9), e334 (2015).
[Crossref] [PubMed]

Srinivasan, V.

Srinivasan, V. J.

Stevenson, K. A.

T. E. de Gooyer, K. A. Stevenson, P. Humphries, D. A. Simpson, T. A. Gardiner, and A. W. Stitt, “Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration,” Invest. Ophthalmol. Vis. Sci. 47(12), 5561–5568 (2006).
[Crossref] [PubMed]

Stigen, T. W.

H. Wang, A. J. Black, J. Zhu, T. W. Stigen, M. K. Al-Qaisi, T. I. Netoff, A. Abosch, and T. Akkin, “Reconstructing micrometer-scale fiber pathways in the brain: multi-contrast optical coherence tomography based tractography,” Neuroimage 58(4), 984–992 (2011).
[Crossref] [PubMed]

Stinson, W. G.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Stitt, A. W.

T. E. de Gooyer, K. A. Stevenson, P. Humphries, D. A. Simpson, T. A. Gardiner, and A. W. Stitt, “Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration,” Invest. Ophthalmol. Vis. Sci. 47(12), 5561–5568 (2006).
[Crossref] [PubMed]

Sullivan, L. S.

S. P. Daiger, S. J. Bowne, and L. S. Sullivan, “Perspective on genes and mutations causing retinitis pigmentosa,” Arch. Ophthalmol. 125(2), 151–158 (2007).
[Crossref] [PubMed]

Swanson, E. A.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Tang, J.

H. Liu, J. Tang, Y. Du, A. Saadane, D. Tonade, I. Samuels, A. Veenstra, K. Palczewski, and T. S. Kern, “Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes,” Invest. Ophthalmol. Vis. Sci. 57(10), 4272–4281 (2016).
[Crossref] [PubMed]

Tang, S.

Tearney, G.

Tonade, D.

H. Liu, J. Tang, Y. Du, A. Saadane, D. Tonade, I. Samuels, A. Veenstra, K. Palczewski, and T. S. Kern, “Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes,” Invest. Ophthalmol. Vis. Sci. 57(10), 4272–4281 (2016).
[Crossref] [PubMed]

Tong, S.

Q. Liu, S. Chen, B. Soetikno, W. Liu, S. Tong, and H. Zhang, “Monitoring acute stroke in mouse model using laser speckle imaging-guided visible-light optical coherence tomography,” IEEE Trans. Biomed. Eng. 65, 2136 (2017).
[PubMed]

Ulrich, R.

Vecino, E.

E. Vecino, “[Animal models in the study of the glaucoma: past, present and future],” Arch. Soc. Esp. Oftalmol. 83(9), 517–519 (2008).
[Crossref] [PubMed]

Veenstra, A.

H. Liu, J. Tang, Y. Du, A. Saadane, D. Tonade, I. Samuels, A. Veenstra, K. Palczewski, and T. S. Kern, “Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes,” Invest. Ophthalmol. Vis. Sci. 57(10), 4272–4281 (2016).
[Crossref] [PubMed]

Vessey, K. A.

E. L. Fletcher, A. I. Jobling, U. Greferath, S. A. Mills, M. Waugh, T. Ho, R. U. de Iongh, J. A. Phipps, and K. A. Vessey, “Studying age-related macular degeneration using animal models,” Optom. Vis. Sci. 91(8), 878–886 (2014).
[Crossref] [PubMed]

Villegas-Perez, M. P.

H. J. Zambarakji, D. J. Keegan, T. M. Holmes, A. S. Halfyard, M. P. Villegas-Perez, D. G. Charteris, F. W. Fitzke, J. Greenwood, and R. D. Lund, “High resolution imaging of fluorescein patterns in RCS rat retinae and their direct correlation with histology,” Exp. Eye Res. 82(1), 164–171 (2006).
[Crossref] [PubMed]

Waheed, N. K.

W. Choi, N. K. Waheed, E. M. Moult, M. Adhi, B. Lee, T. De Carlo, V. Jayaraman, C. R. Baumal, J. S. Duker, and J. G. Fujimoto, “Ultrahigh Speed Swept Source Optical Coherence Tomography Angiography of Retinal and Choriocapillaris Alterations in Diabetic Patients with and without Retinopathy,” Retina 37(1), 11–21 (2017).
[Crossref] [PubMed]

Walter, P.

S. Rösch, C. Aretzweiler, F. Müller, and P. Walter, “Evaluation of Retinal Function and Morphology of the Pink-Eyed Royal College of Surgeons (RCS) Rat: A Comparative Study of in Vivo and in Vitro Methods,” Curr. Eye Res. 42(2), 273–281 (2017).
[Crossref] [PubMed]

Wang, B.

J. Dwelle, S. Liu, B. Wang, A. McElroy, D. Ho, M. K. Markey, T. Milner, and H. G. Rylander, “Thickness, phase retardation, birefringence, and reflectance of the retinal nerve fiber layer in normal and glaucomatous non-human primates,” Invest. Ophthalmol. Vis. Sci. 53(8), 4380–4395 (2012).
[Crossref] [PubMed]

Wang, H.

H. Wang, A. J. Black, J. Zhu, T. W. Stigen, M. K. Al-Qaisi, T. I. Netoff, A. Abosch, and T. Akkin, “Reconstructing micrometer-scale fiber pathways in the brain: multi-contrast optical coherence tomography based tractography,” Neuroimage 58(4), 984–992 (2011).
[Crossref] [PubMed]

Wang, R. K.

Wang, S. S.

Wang, Y.

S. Nusinowitz, Y. Wang, P. Kim, S. Habib, R. Baron, Y. Conley, and M. Gorin, “Retinal Structure in Pre-Clinical Age-Related Macular Degeneration,” Curr. Eye Res. 43(3), 376–382 (2018).
[Crossref] [PubMed]

Y. Feng, Y. Wang, Z. Yang, L. Wu, S. Hoffmann, T. Wieland, N. Gretz, and H. P. Hammes, “Chronic hyperglycemia inhibits vasoregression in a transgenic model of retinal degeneration,” Acta Diabetol. 51(2), 211–218 (2014).
[Crossref] [PubMed]

Waugh, M.

E. L. Fletcher, A. I. Jobling, U. Greferath, S. A. Mills, M. Waugh, T. Ho, R. U. de Iongh, J. A. Phipps, and K. A. Vessey, “Studying age-related macular degeneration using animal models,” Optom. Vis. Sci. 91(8), 878–886 (2014).
[Crossref] [PubMed]

Wedl, M.

C. Schütze, M. Wedl, B. Baumann, M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Progression of retinal pigment epithelial atrophy in antiangiogenic therapy of neovascular age-related macular degeneration,” Am. J. Ophthalmol. 159(6), 1100–1114 (2015).
[Crossref] [PubMed]

Wen, Y.

R. C. Ryals, M. D. Andrews, S. Datta, A. S. Coyner, C. M. Fischer, Y. Wen, M. E. Pennesi, and T. J. McGill, “Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence Tomography,” Invest. Ophthalmol. Vis. Sci. 58(3), 1378–1386 (2017).
[Crossref] [PubMed]

Wieland, T.

Y. Feng, Y. Wang, Z. Yang, L. Wu, S. Hoffmann, T. Wieland, N. Gretz, and H. P. Hammes, “Chronic hyperglycemia inhibits vasoregression in a transgenic model of retinal degeneration,” Acta Diabetol. 51(2), 211–218 (2014).
[Crossref] [PubMed]

Wu, L.

Y. Feng, Y. Wang, Z. Yang, L. Wu, S. Hoffmann, T. Wieland, N. Gretz, and H. P. Hammes, “Chronic hyperglycemia inhibits vasoregression in a transgenic model of retinal degeneration,” Acta Diabetol. 51(2), 211–218 (2014).
[Crossref] [PubMed]

Xi, J.

Yamanaka, M.

N. Nishizawa, H. Kawagoe, M. Yamanaka, M. Matsushima, K. Mori, and T. Kawabe, “Wavelength Dependence of Ultrahigh-Resolution Optical Coherence Tomography Using Supercontinuum for Biomedical Imaging,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1–15 (2019).
[Crossref]

Yang, Z.

Y. Feng, Y. Wang, Z. Yang, L. Wu, S. Hoffmann, T. Wieland, N. Gretz, and H. P. Hammes, “Chronic hyperglycemia inhibits vasoregression in a transgenic model of retinal degeneration,” Acta Diabetol. 51(2), 211–218 (2014).
[Crossref] [PubMed]

Yasuno, Y.

Yen, Y.

Yi, J.

J. Yi, W. Liu, S. Chen, V. Backman, N. Sheibani, C. M. Sorenson, A. A. Fawzi, R. A. Linsenmeier, and H. F. Zhang, “Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation,” Light Sci. Appl. 4(9), e334 (2015).
[Crossref] [PubMed]

J. Yi, S. Chen, V. Backman, and H. F. Zhang, “In vivo functional microangiography by visible-light optical coherence tomography,” Biomed. Opt. Express 5(10), 3603–3612 (2014).
[Crossref] [PubMed]

Yu, S.

Yu, X.

Yuan, W.

Yun, S. H.

Zambarakji, H. J.

H. J. Zambarakji, D. J. Keegan, T. M. Holmes, A. S. Halfyard, M. P. Villegas-Perez, D. G. Charteris, F. W. Fitzke, J. Greenwood, and R. D. Lund, “High resolution imaging of fluorescein patterns in RCS rat retinae and their direct correlation with histology,” Exp. Eye Res. 82(1), 164–171 (2006).
[Crossref] [PubMed]

Zhang, H.

Q. Liu, S. Chen, B. Soetikno, W. Liu, S. Tong, and H. Zhang, “Monitoring acute stroke in mouse model using laser speckle imaging-guided visible-light optical coherence tomography,” IEEE Trans. Biomed. Eng. 65, 2136 (2017).
[PubMed]

Zhang, H. F.

J. Yi, W. Liu, S. Chen, V. Backman, N. Sheibani, C. M. Sorenson, A. A. Fawzi, R. A. Linsenmeier, and H. F. Zhang, “Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation,” Light Sci. Appl. 4(9), e334 (2015).
[Crossref] [PubMed]

J. Yi, S. Chen, V. Backman, and H. F. Zhang, “In vivo functional microangiography by visible-light optical coherence tomography,” Biomed. Opt. Express 5(10), 3603–3612 (2014).
[Crossref] [PubMed]

Zhao, Y.

Zhu, J.

H. Wang, A. J. Black, J. Zhu, T. W. Stigen, M. K. Al-Qaisi, T. I. Netoff, A. Abosch, and T. Akkin, “Reconstructing micrometer-scale fiber pathways in the brain: multi-contrast optical coherence tomography based tractography,” Neuroimage 58(4), 984–992 (2011).
[Crossref] [PubMed]

Acta Diabetol. (1)

Y. Feng, Y. Wang, Z. Yang, L. Wu, S. Hoffmann, T. Wieland, N. Gretz, and H. P. Hammes, “Chronic hyperglycemia inhibits vasoregression in a transgenic model of retinal degeneration,” Acta Diabetol. 51(2), 211–218 (2014).
[Crossref] [PubMed]

Am. J. Ophthalmol. (1)

C. Schütze, M. Wedl, B. Baumann, M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Progression of retinal pigment epithelial atrophy in antiangiogenic therapy of neovascular age-related macular degeneration,” Am. J. Ophthalmol. 159(6), 1100–1114 (2015).
[Crossref] [PubMed]

Appl. Opt. (2)

Arch. Ophthalmol. (1)

S. P. Daiger, S. J. Bowne, and L. S. Sullivan, “Perspective on genes and mutations causing retinitis pigmentosa,” Arch. Ophthalmol. 125(2), 151–158 (2007).
[Crossref] [PubMed]

Arch. Soc. Esp. Oftalmol. (1)

E. Vecino, “[Animal models in the study of the glaucoma: past, present and future],” Arch. Soc. Esp. Oftalmol. 83(9), 517–519 (2008).
[Crossref] [PubMed]

Biomed. Opt. Express (4)

Br. J. Ophthalmol. (2)

M. Battaglia Parodi, M. V. Cicinelli, A. Rabiolo, L. Pierro, M. Gagliardi, G. Bolognesi, and F. Bandello, “Vessel density analysis in patients with retinitis pigmentosa by means of optical coherence tomography angiography,” Br. J. Ophthalmol. 101(4), 428–432 (2017).
[Crossref] [PubMed]

E. Pilotto, L. Frizziero, A. R. Daniele, E. Convento, E. Longhin, F. Guidolin, R. Parrozzani, F. Cavarzeran, and E. Midena, “Early OCT angiography changes of type 1 CNV in exudative AMD treated with anti-VEGF,” Br. J. Ophthalmol. 2018, 311752 (2018).
[Crossref] [PubMed]

Curr. Eye Res. (2)

S. Nusinowitz, Y. Wang, P. Kim, S. Habib, R. Baron, Y. Conley, and M. Gorin, “Retinal Structure in Pre-Clinical Age-Related Macular Degeneration,” Curr. Eye Res. 43(3), 376–382 (2018).
[Crossref] [PubMed]

S. Rösch, C. Aretzweiler, F. Müller, and P. Walter, “Evaluation of Retinal Function and Morphology of the Pink-Eyed Royal College of Surgeons (RCS) Rat: A Comparative Study of in Vivo and in Vitro Methods,” Curr. Eye Res. 42(2), 273–281 (2017).
[Crossref] [PubMed]

Exp. Eye Res. (1)

H. J. Zambarakji, D. J. Keegan, T. M. Holmes, A. S. Halfyard, M. P. Villegas-Perez, D. G. Charteris, F. W. Fitzke, J. Greenwood, and R. D. Lund, “High resolution imaging of fluorescein patterns in RCS rat retinae and their direct correlation with histology,” Exp. Eye Res. 82(1), 164–171 (2006).
[Crossref] [PubMed]

IEEE J. Sel. Top. Quantum Electron. (1)

N. Nishizawa, H. Kawagoe, M. Yamanaka, M. Matsushima, K. Mori, and T. Kawabe, “Wavelength Dependence of Ultrahigh-Resolution Optical Coherence Tomography Using Supercontinuum for Biomedical Imaging,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1–15 (2019).
[Crossref]

IEEE Trans. Biomed. Eng. (1)

Q. Liu, S. Chen, B. Soetikno, W. Liu, S. Tong, and H. Zhang, “Monitoring acute stroke in mouse model using laser speckle imaging-guided visible-light optical coherence tomography,” IEEE Trans. Biomed. Eng. 65, 2136 (2017).
[PubMed]

Invest. Ophthalmol. Vis. Sci. (7)

J. Lammer, M. Bolz, B. Baumann, M. Pircher, B. Gerendas, F. Schlanitz, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Detection and analysis of hard exudates by polarization-sensitive optical coherence tomography in patients with diabetic maculopathy,” Invest. Ophthalmol. Vis. Sci. 55(3), 1564–1571 (2014).
[Crossref] [PubMed]

J. Dwelle, S. Liu, B. Wang, A. McElroy, D. Ho, M. K. Markey, T. Milner, and H. G. Rylander, “Thickness, phase retardation, birefringence, and reflectance of the retinal nerve fiber layer in normal and glaucomatous non-human primates,” Invest. Ophthalmol. Vis. Sci. 53(8), 4380–4395 (2012).
[Crossref] [PubMed]

U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, “Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases,” Invest. Ophthalmol. Vis. Sci. 46(9), 3393–3402 (2005).
[Crossref] [PubMed]

H. Liu, J. Tang, Y. Du, A. Saadane, D. Tonade, I. Samuels, A. Veenstra, K. Palczewski, and T. S. Kern, “Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes,” Invest. Ophthalmol. Vis. Sci. 57(10), 4272–4281 (2016).
[Crossref] [PubMed]

R. C. Ryals, M. D. Andrews, S. Datta, A. S. Coyner, C. M. Fischer, Y. Wen, M. E. Pennesi, and T. J. McGill, “Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence Tomography,” Invest. Ophthalmol. Vis. Sci. 58(3), 1378–1386 (2017).
[Crossref] [PubMed]

T. E. de Gooyer, K. A. Stevenson, P. Humphries, D. A. Simpson, T. A. Gardiner, and A. W. Stitt, “Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration,” Invest. Ophthalmol. Vis. Sci. 47(12), 5561–5568 (2006).
[Crossref] [PubMed]

J. S. Penn, S. Li, and M. I. Naash, “Ambient hypoxia reverses retinal vascular attenuation in a transgenic mouse model of autosomal dominant retinitis pigmentosa,” Invest. Ophthalmol. Vis. Sci. 41(12), 4007–4013 (2000).
[PubMed]

J. Cell Biol. (1)

J. E. Dowling and R. L. Sidman, “Inherited retinal dystrophy in the rat,” J. Cell Biol. 14(1), 73–109 (1962).
[Crossref] [PubMed]

J. Clin. Invest. (1)

M. Friedlander, “Fibrosis and diseases of the eye,” J. Clin. Invest. 117(3), 576–586 (2007).
[Crossref] [PubMed]

Light Sci. Appl. (1)

J. Yi, W. Liu, S. Chen, V. Backman, N. Sheibani, C. M. Sorenson, A. A. Fawzi, R. A. Linsenmeier, and H. F. Zhang, “Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation,” Light Sci. Appl. 4(9), e334 (2015).
[Crossref] [PubMed]

Neurobiol. Dis. (1)

E. Nandrot, E. M. Dufour, A. C. Provost, M. O. Péquignot, S. Bonnel, K. Gogat, D. Marchant, C. Rouillac, B. Sépulchre de Condé, M. T. Bihoreau, C. Shaver, J. L. Dufier, C. Marsac, M. Lathrop, M. Menasche, and M. M. Abitbol, “Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis,” Neurobiol. Dis. 7(66 Pt B), 586–599 (2000).
[Crossref] [PubMed]

Neuroimage (1)

H. Wang, A. J. Black, J. Zhu, T. W. Stigen, M. K. Al-Qaisi, T. I. Netoff, A. Abosch, and T. Akkin, “Reconstructing micrometer-scale fiber pathways in the brain: multi-contrast optical coherence tomography based tractography,” Neuroimage 58(4), 984–992 (2011).
[Crossref] [PubMed]

Opt. Express (5)

Opt. Lett. (3)

Optom. Vis. Sci. (1)

E. L. Fletcher, A. I. Jobling, U. Greferath, S. A. Mills, M. Waugh, T. Ho, R. U. de Iongh, J. A. Phipps, and K. A. Vessey, “Studying age-related macular degeneration using animal models,” Optom. Vis. Sci. 91(8), 878–886 (2014).
[Crossref] [PubMed]

PLoS One (1)

M. Augustin, S. Fialová, T. Himmel, M. Glösmann, T. Lengheimer, D. J. Harper, R. Plasenzotti, M. Pircher, C. K. Hitzenberger, and B. Baumann, “Multi-Functional OCT Enables Longitudinal Study of Retinal Changes in a VLDLR Knockout Mouse Model,” PLoS One 11(10), e0164419 (2016).
[Crossref] [PubMed]

Prog. Retin. Eye Res. (2)

M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Polarization sensitive optical coherence tomography in the human eye,” Prog. Retin. Eye Res. 30(6), 431–451 (2011).
[Crossref] [PubMed]

A. H. Milam, Z. Y. Li, and R. N. Fariss, “Histopathology of the human retina in retinitis pigmentosa,” Prog. Retin. Eye Res. 17(2), 175–205 (1998).
[PubMed]

Retina (1)

W. Choi, N. K. Waheed, E. M. Moult, M. Adhi, B. Lee, T. De Carlo, V. Jayaraman, C. R. Baumal, J. S. Duker, and J. G. Fujimoto, “Ultrahigh Speed Swept Source Optical Coherence Tomography Angiography of Retinal and Choriocapillaris Alterations in Diabetic Patients with and without Retinopathy,” Retina 37(1), 11–21 (2017).
[Crossref] [PubMed]

Science (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Other (1)

J. Barrick, A. Doblas, M. Gardner, P. Sears, L. Ostrowski, and A. L. Oldenburg, “Supercontinuum Parallel Line-field Optical Coherence Tomography for High Sensitivity, Kilohertz Frame Rate Imaging,” in Optics in the Life Sciences Congress (Optical Society of America, San Diego, California, 2017), p. BoM4A.1.

Supplementary Material (2)

NameDescription
» Visualization 1       An OCT 3D reconstruction video showing retinal layers in a SD rat.
» Visualization 2       An OCT 3D reconstruction video showing retinal layers in an RCS rat.

Cited By

OSA participates in Crossref's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (8)

Fig. 1
Fig. 1 Schematic of multi-contrast OCT system. CF: color filter, BS: beam splitter, PC: polarization controller, DM: dichroic mirror, and glass: a glass for dispersion compensation. Contact lens: a Plano-Concave lens (Ocular Instruments).
Fig. 2
Fig. 2 Image processing flowchart.
Fig. 3
Fig. 3 Point spread function and axial resolution over depth.
Fig. 4
Fig. 4 (a) Stability test within 5 min, (b) stability test within 120 min, (c) retardation measurements for linearity verification, (d) measurements of retardation as a function of set orientation of fast axis.
Fig. 5
Fig. 5 OCT images of a SD rat (a) and an RCS rat (b). A lateral average from ten A-scans of the reflectivity profile along the depth defining the different retinal layers in SD (c), and RCS (d) rats. (e) & (f): histology of SD and RCS rat. 3D reconstruction videos of (a) and (b) are illustrated in supplemental information (Visualization 1 and Visualization 2). NFL/GCL: nerve fiber layer/ganglion cell layer, IP: inner plexiform, IN: inner nuclear, OP: outer plexiform, ON: outer nuclear, ELM: external limiting membrane, IS/OS: photoreceptor inner segment/outer segment, RPE: retinal pigment epithelium.
Fig. 6
Fig. 6 Fundus photography (a, f) and three layers of OCT angiography of a healthy SD rat (b: NFL-GCL; c: IP layer; d: OP layer) and RCS rat (g: NFL-GCL; h: IP layer; i: OP layer) respectively. (e & j) depth-color coded microvascular en-face projection of the healthy SD rat and RCS rat (blue: NFL-GCL layer; green: IP layer, red: OP layer).
Fig. 7
Fig. 7 OCT structure, retardation image, and one representative retardation signal as a function of depth in a healthy SD rat (a), (c), and (e), and an RCS rat (b), (d), and (f), and their corresponding histology (g) and (h). Dual arrows in (c) and (d) pointed out the boundary of the changing retardation. Dual arrows in (e)&(f) pointed out the distance from RPE to the retardation value reach to 45°.
Fig. 8
Fig. 8 Multi-contrast OCT images (a) schematic plot, (b-d): structural image, (e-g) retardation image, (h-j) depth-color coded microvascular enface projection (blue: NFL-GCL layer; green: IPL layer, red: OPL layer). The SD rat (b, e, and h); RCS rat (c, f, and i); and LE rat (d, g, and j).

Equations (3)

Equations on this page are rendered with MathJax. Learn more.

  F T 1 { S V ( k ) } S V ( z ) = R s ( z ) sin   ( δ ( z ) ) exp ( i V )
  F T 1 { S H ( k ) } S H ( z ) = R s ( z ) cos   ( δ ( z ) ) exp ( i H )
  F l o w ( x , z ) = 1 N 1 i = 0 N 1 | S i + 1 V ( x , z ) S i V ( x , z ) | + 1 N 1 i = 0 N 1 | S i + 1 H ( x , z ) S i H ( x , z ) |

Metrics