Abstract

In time-domain diffuse optics the sensitivity to localized absorption changes buried inside a diffusive medium depends strongly on the interplay between instrumental, optical and geometrical parameters, which can hinder the theoretical advantages of novel measurement strategies like the short source-detector distance approach. Here, we present a study based on experimental measurements and simulations to comprehensively evaluate the effect of all different parameters. Results are evaluated exploiting standardized figures of merit, like contrast and contrast-to-noise ratio, to quantify the system sensitivity to deep localized absorption perturbations. Key findings show that the most critical hardware parameter is the memory effect which ultimately limits the dynamic range. Further, a choice of the source-detector distance around 10 mm seems to be a good compromise to compensate non-idealities in practical systems still preserving the advantages of short distances. This work provides both indications for users about the best measurement conditions and strategies, and for technology developers to identify the most crucial hardware features in view of next generation diffuse optics systems.

© 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

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2019 (1)

M. Renna, M. Buttafava, A. Behera, M. Zanoletti, L. Di Sieno, A. Dalla Mora, D. Contini, and A. Tosi, “Eight-wavelength, dual detection-channel instrument for near-infrared time-resolved diffuse optical spectroscopy,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1 (2019).

2017 (1)

L. Di Sieno, J. Nissinen, L. Hallman, E. Martinenghi, D. Contini, A. Pifferi, J. Kostamovaara, and A. D. Mora, “Miniaturized pulsed laser source for time-domain diffuse optics routes to wearable devices,” J. Biomed. Opt. 22(8), 1–9 (2017).
[Crossref] [PubMed]

2016 (4)

A. Pifferi, D. Contini, A. D. Mora, A. Farina, L. Spinelli, and A. Torricelli, “New frontiers in time-domain diffuse optics, a review,” J. Biomed. Opt. 21(9), 091310 (2016).
[Crossref] [PubMed]

L. Di Sieno, H. Wabnitz, A. Pifferi, M. Mazurenka, Y. Hoshi, A. Dalla Mora, D. Contini, G. Boso, W. Becker, F. Martelli, A. Tosi, and R. Macdonald, “Characterization of a time-resolved non-contact scanning diffuse optical imaging system exploiting fast-gated single-photon avalanche diode detection,” Rev. Sci. Instrum. 87(3), 035118 (2016).
[Crossref] [PubMed]

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

F. Martelli, T. Binzoni, A. Pifferi, L. Spinelli, A. Farina, and A. Torricelli, “There’s plenty of light at the bottom: statistics of photon penetration depth in random media,” Sci. Rep. 6(1), 27057 (2016).
[Crossref] [PubMed]

2015 (4)

A. Puszka, L. Di Sieno, A. D. Mora, A. Pifferi, D. Contini, A. Planat-Chrétien, A. Koenig, G. Boso, A. Tosi, L. Hervé, and J.-M. Dinten, “Spatial resolution in depth for time-resolved diffuse optical tomography using short source-detector separations,” Biomed. Opt. Express 6(1), 1–10 (2015).
[Crossref] [PubMed]

A. Dalla Mora, A. Tosi, D. Contini, L. Di Sieno, G. Boso, F. Villa, and A. Pifferi, “Memory effect in silicon time-gated single-photon avalanche diodes,” J. Appl. Phys. 117(11), 114501 (2015).
[Crossref]

A. D. Mora, D. Contini, S. Arridge, F. Martelli, A. Tosi, G. Boso, A. Farina, T. Durduran, E. Martinenghi, A. Torricelli, and A. Pifferi, “Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity,” Biomed. Opt. Express 6(5), 1749–1760 (2015).
[Crossref] [PubMed]

D. Contini, A. Dalla Mora, L. Spinelli, A. Farina, A. Torricelli, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, G. Boso, F. Zappa, and A. Pifferi, “Effects of time-gated detection in diffuse optical imaging at short source-detector separation,” J. Phys. D Appl. Phys. 48(4), 045401 (2015).
[Crossref]

2014 (9)

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

F. Martelli, P. Di Ninni, G. Zaccanti, D. Contini, L. Spinelli, A. Torricelli, R. Cubeddu, H. Wabnitz, M. Mazurenka, R. Macdonald, A. Sassaroli, and A. Pifferi, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: experimental implementation,” J. Biomed. Opt. 19(7), 076011 (2014).
[Crossref] [PubMed]

A. Sassaroli, A. Pifferi, D. Contini, A. Torricelli, L. Spinelli, H. Wabnitz, P. Di Ninni, G. Zaccanti, and F. Martelli, “Forward solvers for photon migration in the presence of highly and totally absorbing objects embedded inside diffusive media,” J. Opt. Soc. Am. A 31(3), 460–469 (2014).
[Crossref] [PubMed]

L. D. Sieno, A. D. Mora, G. Boso, A. Tosi, A. Pifferi, R. Cubeddu, and D. Contini, “Diffuse optics using a dual window fast-gated counter,” Appl. Opt. 53(31), 7394–7401 (2014).
[Crossref] [PubMed]

F. Scholkmann, S. Kleiser, A. J. Metz, R. Zimmermann, J. Mata Pavia, U. Wolf, and M. Wolf, “A review on continuous wave functional near-infrared spectroscopy and imaging instrumentation and methodology,” Neuroimage 85(Pt 1), 6–27 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

G. Quarto, L. Spinelli, A. Pifferi, A. Torricelli, R. Cubeddu, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and P. Taroni, “Estimate of tissue composition in malignant and benign breast lesions by time-domain optical mammography,” Biomed. Opt. Express 5(10), 3684–3698 (2014).
[Crossref] [PubMed]

A. Torricelli, D. Contini, A. Pifferi, M. Caffini, R. Re, L. Zucchelli, and L. Spinelli, “Time domain functional NIRS imaging for human brain mapping,” Neuroimage 85(Pt 1), 28–50 (2014).
[Crossref] [PubMed]

2013 (5)

P. Taroni, G. Quarto, A. Pifferi, F. Ieva, A. M. Paganoni, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and R. Cubeddu, “Optical identification of subjects at high risk for developing breast cancer,” J. Biomed. Opt. 18(6), 060507 (2013).
[Crossref] [PubMed]

L. Enfield, G. Cantanhede, M. Douek, V. Ramalingam, A. Purushotham, J. Hebden, and A. Gibson, “Monitoring the response to neoadjuvant hormone therapy for locally advanced breast cancer using three-dimensional time-resolved optical mammography,” J. Biomed. Opt. 18(5), 056012 (2013).
[Crossref] [PubMed]

I. Bargigia, A. Nevin, A. Farina, A. Pifferi, C. D’Andrea, M. Karlsson, P. Lundin, G. Somesfalean, and S. Svanberg, “Diffuse optical techniques applied to wood characterisation,” J. Near Infrared Spectrosc. 21(4), 259–268 (2013).
[Crossref]

G. Boso, A. Dalla Mora, A. Della Frera, and A. Tosi, “Fast-gating of single-photon avalanche diodes with 200 ps transitions and 30 ps timing jitter,” Sens. Actuators A Phys. 191, 61–67 (2013).
[Crossref]

F. Martelli, A. Pifferi, D. Contini, L. Spinelli, A. Torricelli, H. Wabnitz, R. Macdonald, A. Sassaroli, and G. Zaccanti, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 1: Basic concepts,” J. Biomed. Opt. 18(6), 066014 (2013).
[Crossref] [PubMed]

2012 (5)

A. Dalla Mora, D. Contini, A. Pifferi, R. Cubeddu, A. Tosi, and F. Zappa, “Afterpulse-like noise limits dynamic range in time-gated applications of thin-junction silicon single-photon avalanche diode,” Appl. Phys. Lett. 100(24), 241111 (2012).
[Crossref]

E. Alerstam, T. Svensson, S. Andersson-Engels, L. Spinelli, D. Contini, A. Dalla Mora, A. Tosi, F. Zappa, and A. Pifferi, “Single-fiber diffuse optical time-of-flight spectroscopy,” Opt. Lett. 37(14), 2877–2879 (2012).
[Crossref] [PubMed]

A. Bellincontro, A. Taticchi, M. Servili, S. Esposto, D. Farinelli, and F. Mencarelli, “Feasible application of a portable nir-AOTF tool for on-field prediction of phenolic compounds during the ripening of olives for oil production,” J. Agric. Food Chem. 60(10), 2665–2673 (2012).
[Crossref] [PubMed]

D. Contini, L. Zucchelli, L. Spinelli, M. Caffini, R. Re, A. Pifferi, R. Cubeddu, and A. Torricelli, “Review: Brain and muscle near infrared spectroscopy/imaging techniques,” J. Near Infrared Spectrosc. 20(1), 15–27 (2012).
[Crossref]

M. Ferrari and V. Quaresima, “A brief review on the history of human functional near-infrared spectroscopy (fNIRS) development and fields of application,” Neuroimage 63(2), 921–935 (2012).
[Crossref] [PubMed]

2011 (2)

2010 (2)

A. Dalla Mora, A. Tosi, F. Zappa, S. Cova, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon avalanche diode for wide dynamic range near infrared spectroscopy,” Sel. Top. Quantum Electron. 16(4), 1023–1030 (2010).
[Crossref]

T. Durduran, R. Choe, W. B. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010).
[Crossref] [PubMed]

2008 (1)

A. Pifferi, A. Torricelli, L. Spinelli, D. Contini, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, A. Dalla Mora, F. Zappa, and S. Cova, “Time-Resolved Diffuse Reflectance Using Small Source-Detector Separation and Fast Single-Photon Gating,” Phys. Rev. Lett. 100(13), 138101 (2008).
[Crossref] [PubMed]

2005 (1)

A. Torricelli, A. Pifferi, L. Spinelli, R. Cubeddu, F. Martelli, S. Del Bianco, and G. Zaccanti, “Time-Resolved Reflectance at Null Source-Detector Separation: Improving Contrast and Resolution in Diffuse Optical Imaging,” Phys. Rev. Lett. 95(7), 078101 (2005).
[Crossref] [PubMed]

2004 (2)

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, “Mapping of calf muscle oxygenation and haemoglobin content during dynamic plantar flexion exercise by multi-channel time-resolved near-infrared spectroscopy,” Phys. Med. Biol. 49(5), 685–699 (2004).
[Crossref] [PubMed]

A. Pifferi, A. Torricelli, P. Taroni, A. Bassi, E. Chikoidze, E. Giambattistelli, and R. Cubeddu, “Optical biopsy of bone tissue: a step toward the diagnosis of bone pathologies,” J. Biomed. Opt. 9(3), 474–480 (2004).
[Crossref] [PubMed]

2002 (1)

T. Durduran, R. Choe, J. P. Culver, L. Zubkov, M. J. Holboke, J. Giammarco, B. Chance, and A. G. Yodh, “Bulk optical properties of healthy female breast tissue,” Phys. Med. Biol. 47(16), 2847–2861 (2002).
[Crossref] [PubMed]

1995 (1)

A. Yodh and B. Chance, “Spectroscopy and imaging with diffusing light,” Phys. Today 48(3), 34–41 (1995).
[Crossref]

1989 (1)

Abbate, F.

G. Quarto, L. Spinelli, A. Pifferi, A. Torricelli, R. Cubeddu, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and P. Taroni, “Estimate of tissue composition in malignant and benign breast lesions by time-domain optical mammography,” Biomed. Opt. Express 5(10), 3684–3698 (2014).
[Crossref] [PubMed]

P. Taroni, G. Quarto, A. Pifferi, F. Ieva, A. M. Paganoni, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and R. Cubeddu, “Optical identification of subjects at high risk for developing breast cancer,” J. Biomed. Opt. 18(6), 060507 (2013).
[Crossref] [PubMed]

Acerbi, F.

A. Tosi, A. Dalla Mora, A. Della Frera, F. Acerbi, A. Bahgat Shehata, and F. Zappa, “Advanced single photon counting instrumentation for SPADs,” Proc. SPIE 7945, 79452O (2011).
[Crossref]

Alerstam, E.

Andersson-Engels, S.

Aribert, M.

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

Arridge, S.

Bahgat Shehata, A.

A. Tosi, A. Dalla Mora, A. Della Frera, F. Acerbi, A. Bahgat Shehata, and F. Zappa, “Advanced single photon counting instrumentation for SPADs,” Proc. SPIE 7945, 79452O (2011).
[Crossref]

Baker, W. B.

T. Durduran, R. Choe, W. B. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010).
[Crossref] [PubMed]

Balestreri, N.

G. Quarto, L. Spinelli, A. Pifferi, A. Torricelli, R. Cubeddu, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and P. Taroni, “Estimate of tissue composition in malignant and benign breast lesions by time-domain optical mammography,” Biomed. Opt. Express 5(10), 3684–3698 (2014).
[Crossref] [PubMed]

P. Taroni, G. Quarto, A. Pifferi, F. Ieva, A. M. Paganoni, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and R. Cubeddu, “Optical identification of subjects at high risk for developing breast cancer,” J. Biomed. Opt. 18(6), 060507 (2013).
[Crossref] [PubMed]

Bargigia, I.

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

I. Bargigia, A. Nevin, A. Farina, A. Pifferi, C. D’Andrea, M. Karlsson, P. Lundin, G. Somesfalean, and S. Svanberg, “Diffuse optical techniques applied to wood characterisation,” J. Near Infrared Spectrosc. 21(4), 259–268 (2013).
[Crossref]

Baribeau, F.

Bassi, A.

A. Pifferi, A. Torricelli, P. Taroni, A. Bassi, E. Chikoidze, E. Giambattistelli, and R. Cubeddu, “Optical biopsy of bone tissue: a step toward the diagnosis of bone pathologies,” J. Biomed. Opt. 9(3), 474–480 (2004).
[Crossref] [PubMed]

Becker, W.

L. Di Sieno, H. Wabnitz, A. Pifferi, M. Mazurenka, Y. Hoshi, A. Dalla Mora, D. Contini, G. Boso, W. Becker, F. Martelli, A. Tosi, and R. Macdonald, “Characterization of a time-resolved non-contact scanning diffuse optical imaging system exploiting fast-gated single-photon avalanche diode detection,” Rev. Sci. Instrum. 87(3), 035118 (2016).
[Crossref] [PubMed]

Behera, A.

M. Renna, M. Buttafava, A. Behera, M. Zanoletti, L. Di Sieno, A. Dalla Mora, D. Contini, and A. Tosi, “Eight-wavelength, dual detection-channel instrument for near-infrared time-resolved diffuse optical spectroscopy,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1 (2019).

Bellincontro, A.

A. Bellincontro, A. Taticchi, M. Servili, S. Esposto, D. Farinelli, and F. Mencarelli, “Feasible application of a portable nir-AOTF tool for on-field prediction of phenolic compounds during the ripening of olives for oil production,” J. Agric. Food Chem. 60(10), 2665–2673 (2012).
[Crossref] [PubMed]

Bénazech-Lavoué, M.

Berger, M.

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

Bérubé-Lauzière, Y.

Bettega, G.

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

Binzoni, T.

F. Martelli, T. Binzoni, A. Pifferi, L. Spinelli, A. Farina, and A. Torricelli, “There’s plenty of light at the bottom: statistics of photon penetration depth in random media,” Sci. Rep. 6(1), 27057 (2016).
[Crossref] [PubMed]

Biscotti, G.

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, “Mapping of calf muscle oxygenation and haemoglobin content during dynamic plantar flexion exercise by multi-channel time-resolved near-infrared spectroscopy,” Phys. Med. Biol. 49(5), 685–699 (2004).
[Crossref] [PubMed]

Bodnar, O.

Boso, G.

L. Di Sieno, H. Wabnitz, A. Pifferi, M. Mazurenka, Y. Hoshi, A. Dalla Mora, D. Contini, G. Boso, W. Becker, F. Martelli, A. Tosi, and R. Macdonald, “Characterization of a time-resolved non-contact scanning diffuse optical imaging system exploiting fast-gated single-photon avalanche diode detection,” Rev. Sci. Instrum. 87(3), 035118 (2016).
[Crossref] [PubMed]

D. Contini, A. Dalla Mora, L. Spinelli, A. Farina, A. Torricelli, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, G. Boso, F. Zappa, and A. Pifferi, “Effects of time-gated detection in diffuse optical imaging at short source-detector separation,” J. Phys. D Appl. Phys. 48(4), 045401 (2015).
[Crossref]

A. Dalla Mora, A. Tosi, D. Contini, L. Di Sieno, G. Boso, F. Villa, and A. Pifferi, “Memory effect in silicon time-gated single-photon avalanche diodes,” J. Appl. Phys. 117(11), 114501 (2015).
[Crossref]

A. D. Mora, D. Contini, S. Arridge, F. Martelli, A. Tosi, G. Boso, A. Farina, T. Durduran, E. Martinenghi, A. Torricelli, and A. Pifferi, “Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity,” Biomed. Opt. Express 6(5), 1749–1760 (2015).
[Crossref] [PubMed]

A. Puszka, L. Di Sieno, A. D. Mora, A. Pifferi, D. Contini, A. Planat-Chrétien, A. Koenig, G. Boso, A. Tosi, L. Hervé, and J.-M. Dinten, “Spatial resolution in depth for time-resolved diffuse optical tomography using short source-detector separations,” Biomed. Opt. Express 6(1), 1–10 (2015).
[Crossref] [PubMed]

L. D. Sieno, A. D. Mora, G. Boso, A. Tosi, A. Pifferi, R. Cubeddu, and D. Contini, “Diffuse optics using a dual window fast-gated counter,” Appl. Opt. 53(31), 7394–7401 (2014).
[Crossref] [PubMed]

G. Boso, A. Dalla Mora, A. Della Frera, and A. Tosi, “Fast-gating of single-photon avalanche diodes with 200 ps transitions and 30 ps timing jitter,” Sens. Actuators A Phys. 191, 61–67 (2013).
[Crossref]

Botwicz, M.

Bouchard, J.-P.

Buttafava, M.

M. Renna, M. Buttafava, A. Behera, M. Zanoletti, L. Di Sieno, A. Dalla Mora, D. Contini, and A. Tosi, “Eight-wavelength, dual detection-channel instrument for near-infrared time-resolved diffuse optical spectroscopy,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1 (2019).

Caffini, M.

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

A. Torricelli, D. Contini, A. Pifferi, M. Caffini, R. Re, L. Zucchelli, and L. Spinelli, “Time domain functional NIRS imaging for human brain mapping,” Neuroimage 85(Pt 1), 28–50 (2014).
[Crossref] [PubMed]

D. Contini, L. Zucchelli, L. Spinelli, M. Caffini, R. Re, A. Pifferi, R. Cubeddu, and A. Torricelli, “Review: Brain and muscle near infrared spectroscopy/imaging techniques,” J. Near Infrared Spectrosc. 20(1), 15–27 (2012).
[Crossref]

Cantanhede, G.

L. Enfield, G. Cantanhede, M. Douek, V. Ramalingam, A. Purushotham, J. Hebden, and A. Gibson, “Monitoring the response to neoadjuvant hormone therapy for locally advanced breast cancer using three-dimensional time-resolved optical mammography,” J. Biomed. Opt. 18(5), 056012 (2013).
[Crossref] [PubMed]

Cassano, E.

G. Quarto, L. Spinelli, A. Pifferi, A. Torricelli, R. Cubeddu, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and P. Taroni, “Estimate of tissue composition in malignant and benign breast lesions by time-domain optical mammography,” Biomed. Opt. Express 5(10), 3684–3698 (2014).
[Crossref] [PubMed]

P. Taroni, G. Quarto, A. Pifferi, F. Ieva, A. M. Paganoni, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and R. Cubeddu, “Optical identification of subjects at high risk for developing breast cancer,” J. Biomed. Opt. 18(6), 060507 (2013).
[Crossref] [PubMed]

Chance, B.

T. Durduran, R. Choe, J. P. Culver, L. Zubkov, M. J. Holboke, J. Giammarco, B. Chance, and A. G. Yodh, “Bulk optical properties of healthy female breast tissue,” Phys. Med. Biol. 47(16), 2847–2861 (2002).
[Crossref] [PubMed]

A. Yodh and B. Chance, “Spectroscopy and imaging with diffusing light,” Phys. Today 48(3), 34–41 (1995).
[Crossref]

Chikoidze, E.

A. Pifferi, A. Torricelli, P. Taroni, A. Bassi, E. Chikoidze, E. Giambattistelli, and R. Cubeddu, “Optical biopsy of bone tissue: a step toward the diagnosis of bone pathologies,” J. Biomed. Opt. 9(3), 474–480 (2004).
[Crossref] [PubMed]

Choe, R.

T. Durduran, R. Choe, W. B. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010).
[Crossref] [PubMed]

T. Durduran, R. Choe, J. P. Culver, L. Zubkov, M. J. Holboke, J. Giammarco, B. Chance, and A. G. Yodh, “Bulk optical properties of healthy female breast tissue,” Phys. Med. Biol. 47(16), 2847–2861 (2002).
[Crossref] [PubMed]

Coll, J.-L.

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

Contini, D.

M. Renna, M. Buttafava, A. Behera, M. Zanoletti, L. Di Sieno, A. Dalla Mora, D. Contini, and A. Tosi, “Eight-wavelength, dual detection-channel instrument for near-infrared time-resolved diffuse optical spectroscopy,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1 (2019).

L. Di Sieno, J. Nissinen, L. Hallman, E. Martinenghi, D. Contini, A. Pifferi, J. Kostamovaara, and A. D. Mora, “Miniaturized pulsed laser source for time-domain diffuse optics routes to wearable devices,” J. Biomed. Opt. 22(8), 1–9 (2017).
[Crossref] [PubMed]

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

A. Pifferi, D. Contini, A. D. Mora, A. Farina, L. Spinelli, and A. Torricelli, “New frontiers in time-domain diffuse optics, a review,” J. Biomed. Opt. 21(9), 091310 (2016).
[Crossref] [PubMed]

L. Di Sieno, H. Wabnitz, A. Pifferi, M. Mazurenka, Y. Hoshi, A. Dalla Mora, D. Contini, G. Boso, W. Becker, F. Martelli, A. Tosi, and R. Macdonald, “Characterization of a time-resolved non-contact scanning diffuse optical imaging system exploiting fast-gated single-photon avalanche diode detection,” Rev. Sci. Instrum. 87(3), 035118 (2016).
[Crossref] [PubMed]

D. Contini, A. Dalla Mora, L. Spinelli, A. Farina, A. Torricelli, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, G. Boso, F. Zappa, and A. Pifferi, “Effects of time-gated detection in diffuse optical imaging at short source-detector separation,” J. Phys. D Appl. Phys. 48(4), 045401 (2015).
[Crossref]

A. Dalla Mora, A. Tosi, D. Contini, L. Di Sieno, G. Boso, F. Villa, and A. Pifferi, “Memory effect in silicon time-gated single-photon avalanche diodes,” J. Appl. Phys. 117(11), 114501 (2015).
[Crossref]

A. D. Mora, D. Contini, S. Arridge, F. Martelli, A. Tosi, G. Boso, A. Farina, T. Durduran, E. Martinenghi, A. Torricelli, and A. Pifferi, “Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity,” Biomed. Opt. Express 6(5), 1749–1760 (2015).
[Crossref] [PubMed]

A. Puszka, L. Di Sieno, A. D. Mora, A. Pifferi, D. Contini, A. Planat-Chrétien, A. Koenig, G. Boso, A. Tosi, L. Hervé, and J.-M. Dinten, “Spatial resolution in depth for time-resolved diffuse optical tomography using short source-detector separations,” Biomed. Opt. Express 6(1), 1–10 (2015).
[Crossref] [PubMed]

A. Sassaroli, A. Pifferi, D. Contini, A. Torricelli, L. Spinelli, H. Wabnitz, P. Di Ninni, G. Zaccanti, and F. Martelli, “Forward solvers for photon migration in the presence of highly and totally absorbing objects embedded inside diffusive media,” J. Opt. Soc. Am. A 31(3), 460–469 (2014).
[Crossref] [PubMed]

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

F. Martelli, P. Di Ninni, G. Zaccanti, D. Contini, L. Spinelli, A. Torricelli, R. Cubeddu, H. Wabnitz, M. Mazurenka, R. Macdonald, A. Sassaroli, and A. Pifferi, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: experimental implementation,” J. Biomed. Opt. 19(7), 076011 (2014).
[Crossref] [PubMed]

A. Torricelli, D. Contini, A. Pifferi, M. Caffini, R. Re, L. Zucchelli, and L. Spinelli, “Time domain functional NIRS imaging for human brain mapping,” Neuroimage 85(Pt 1), 28–50 (2014).
[Crossref] [PubMed]

L. D. Sieno, A. D. Mora, G. Boso, A. Tosi, A. Pifferi, R. Cubeddu, and D. Contini, “Diffuse optics using a dual window fast-gated counter,” Appl. Opt. 53(31), 7394–7401 (2014).
[Crossref] [PubMed]

F. Martelli, A. Pifferi, D. Contini, L. Spinelli, A. Torricelli, H. Wabnitz, R. Macdonald, A. Sassaroli, and G. Zaccanti, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 1: Basic concepts,” J. Biomed. Opt. 18(6), 066014 (2013).
[Crossref] [PubMed]

A. Dalla Mora, D. Contini, A. Pifferi, R. Cubeddu, A. Tosi, and F. Zappa, “Afterpulse-like noise limits dynamic range in time-gated applications of thin-junction silicon single-photon avalanche diode,” Appl. Phys. Lett. 100(24), 241111 (2012).
[Crossref]

D. Contini, L. Zucchelli, L. Spinelli, M. Caffini, R. Re, A. Pifferi, R. Cubeddu, and A. Torricelli, “Review: Brain and muscle near infrared spectroscopy/imaging techniques,” J. Near Infrared Spectrosc. 20(1), 15–27 (2012).
[Crossref]

E. Alerstam, T. Svensson, S. Andersson-Engels, L. Spinelli, D. Contini, A. Dalla Mora, A. Tosi, F. Zappa, and A. Pifferi, “Single-fiber diffuse optical time-of-flight spectroscopy,” Opt. Lett. 37(14), 2877–2879 (2012).
[Crossref] [PubMed]

A. Tosi, A. Dalla Mora, F. Zappa, A. Gulinatti, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon counting technique widens dynamic range and speeds up acquisition time in time-resolved measurements,” Opt. Express 19(11), 10735–10746 (2011).
[Crossref] [PubMed]

A. Dalla Mora, A. Tosi, F. Zappa, S. Cova, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon avalanche diode for wide dynamic range near infrared spectroscopy,” Sel. Top. Quantum Electron. 16(4), 1023–1030 (2010).
[Crossref]

A. Pifferi, A. Torricelli, L. Spinelli, D. Contini, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, A. Dalla Mora, F. Zappa, and S. Cova, “Time-Resolved Diffuse Reflectance Using Small Source-Detector Separation and Fast Single-Photon Gating,” Phys. Rev. Lett. 100(13), 138101 (2008).
[Crossref] [PubMed]

Cooper, R.

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

Cope, M.

D. T. Delpy and M. Cope, “Quantification in tissue near-infrared spectroscopy uantification in tissue near-infrared spectroscopy,” 352, 649 (1997).

Cova, S.

A. Dalla Mora, A. Tosi, F. Zappa, S. Cova, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon avalanche diode for wide dynamic range near infrared spectroscopy,” Sel. Top. Quantum Electron. 16(4), 1023–1030 (2010).
[Crossref]

A. Pifferi, A. Torricelli, L. Spinelli, D. Contini, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, A. Dalla Mora, F. Zappa, and S. Cova, “Time-Resolved Diffuse Reflectance Using Small Source-Detector Separation and Fast Single-Photon Gating,” Phys. Rev. Lett. 100(13), 138101 (2008).
[Crossref] [PubMed]

Cubeddu, R.

D. Contini, A. Dalla Mora, L. Spinelli, A. Farina, A. Torricelli, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, G. Boso, F. Zappa, and A. Pifferi, “Effects of time-gated detection in diffuse optical imaging at short source-detector separation,” J. Phys. D Appl. Phys. 48(4), 045401 (2015).
[Crossref]

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

L. D. Sieno, A. D. Mora, G. Boso, A. Tosi, A. Pifferi, R. Cubeddu, and D. Contini, “Diffuse optics using a dual window fast-gated counter,” Appl. Opt. 53(31), 7394–7401 (2014).
[Crossref] [PubMed]

F. Martelli, P. Di Ninni, G. Zaccanti, D. Contini, L. Spinelli, A. Torricelli, R. Cubeddu, H. Wabnitz, M. Mazurenka, R. Macdonald, A. Sassaroli, and A. Pifferi, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: experimental implementation,” J. Biomed. Opt. 19(7), 076011 (2014).
[Crossref] [PubMed]

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

G. Quarto, L. Spinelli, A. Pifferi, A. Torricelli, R. Cubeddu, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and P. Taroni, “Estimate of tissue composition in malignant and benign breast lesions by time-domain optical mammography,” Biomed. Opt. Express 5(10), 3684–3698 (2014).
[Crossref] [PubMed]

P. Taroni, G. Quarto, A. Pifferi, F. Ieva, A. M. Paganoni, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and R. Cubeddu, “Optical identification of subjects at high risk for developing breast cancer,” J. Biomed. Opt. 18(6), 060507 (2013).
[Crossref] [PubMed]

A. Dalla Mora, D. Contini, A. Pifferi, R. Cubeddu, A. Tosi, and F. Zappa, “Afterpulse-like noise limits dynamic range in time-gated applications of thin-junction silicon single-photon avalanche diode,” Appl. Phys. Lett. 100(24), 241111 (2012).
[Crossref]

D. Contini, L. Zucchelli, L. Spinelli, M. Caffini, R. Re, A. Pifferi, R. Cubeddu, and A. Torricelli, “Review: Brain and muscle near infrared spectroscopy/imaging techniques,” J. Near Infrared Spectrosc. 20(1), 15–27 (2012).
[Crossref]

A. Tosi, A. Dalla Mora, F. Zappa, A. Gulinatti, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon counting technique widens dynamic range and speeds up acquisition time in time-resolved measurements,” Opt. Express 19(11), 10735–10746 (2011).
[Crossref] [PubMed]

A. Dalla Mora, A. Tosi, F. Zappa, S. Cova, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon avalanche diode for wide dynamic range near infrared spectroscopy,” Sel. Top. Quantum Electron. 16(4), 1023–1030 (2010).
[Crossref]

A. Pifferi, A. Torricelli, L. Spinelli, D. Contini, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, A. Dalla Mora, F. Zappa, and S. Cova, “Time-Resolved Diffuse Reflectance Using Small Source-Detector Separation and Fast Single-Photon Gating,” Phys. Rev. Lett. 100(13), 138101 (2008).
[Crossref] [PubMed]

A. Torricelli, A. Pifferi, L. Spinelli, R. Cubeddu, F. Martelli, S. Del Bianco, and G. Zaccanti, “Time-Resolved Reflectance at Null Source-Detector Separation: Improving Contrast and Resolution in Diffuse Optical Imaging,” Phys. Rev. Lett. 95(7), 078101 (2005).
[Crossref] [PubMed]

A. Pifferi, A. Torricelli, P. Taroni, A. Bassi, E. Chikoidze, E. Giambattistelli, and R. Cubeddu, “Optical biopsy of bone tissue: a step toward the diagnosis of bone pathologies,” J. Biomed. Opt. 9(3), 474–480 (2004).
[Crossref] [PubMed]

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, “Mapping of calf muscle oxygenation and haemoglobin content during dynamic plantar flexion exercise by multi-channel time-resolved near-infrared spectroscopy,” Phys. Med. Biol. 49(5), 685–699 (2004).
[Crossref] [PubMed]

Culver, J. P.

T. Durduran, R. Choe, J. P. Culver, L. Zubkov, M. J. Holboke, J. Giammarco, B. Chance, and A. G. Yodh, “Bulk optical properties of healthy female breast tissue,” Phys. Med. Biol. 47(16), 2847–2861 (2002).
[Crossref] [PubMed]

D’Andrea, C.

Dalla Mora, A.

M. Renna, M. Buttafava, A. Behera, M. Zanoletti, L. Di Sieno, A. Dalla Mora, D. Contini, and A. Tosi, “Eight-wavelength, dual detection-channel instrument for near-infrared time-resolved diffuse optical spectroscopy,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1 (2019).

L. Di Sieno, H. Wabnitz, A. Pifferi, M. Mazurenka, Y. Hoshi, A. Dalla Mora, D. Contini, G. Boso, W. Becker, F. Martelli, A. Tosi, and R. Macdonald, “Characterization of a time-resolved non-contact scanning diffuse optical imaging system exploiting fast-gated single-photon avalanche diode detection,” Rev. Sci. Instrum. 87(3), 035118 (2016).
[Crossref] [PubMed]

A. Dalla Mora, A. Tosi, D. Contini, L. Di Sieno, G. Boso, F. Villa, and A. Pifferi, “Memory effect in silicon time-gated single-photon avalanche diodes,” J. Appl. Phys. 117(11), 114501 (2015).
[Crossref]

D. Contini, A. Dalla Mora, L. Spinelli, A. Farina, A. Torricelli, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, G. Boso, F. Zappa, and A. Pifferi, “Effects of time-gated detection in diffuse optical imaging at short source-detector separation,” J. Phys. D Appl. Phys. 48(4), 045401 (2015).
[Crossref]

G. Boso, A. Dalla Mora, A. Della Frera, and A. Tosi, “Fast-gating of single-photon avalanche diodes with 200 ps transitions and 30 ps timing jitter,” Sens. Actuators A Phys. 191, 61–67 (2013).
[Crossref]

A. Dalla Mora, D. Contini, A. Pifferi, R. Cubeddu, A. Tosi, and F. Zappa, “Afterpulse-like noise limits dynamic range in time-gated applications of thin-junction silicon single-photon avalanche diode,” Appl. Phys. Lett. 100(24), 241111 (2012).
[Crossref]

E. Alerstam, T. Svensson, S. Andersson-Engels, L. Spinelli, D. Contini, A. Dalla Mora, A. Tosi, F. Zappa, and A. Pifferi, “Single-fiber diffuse optical time-of-flight spectroscopy,” Opt. Lett. 37(14), 2877–2879 (2012).
[Crossref] [PubMed]

A. Tosi, A. Dalla Mora, A. Della Frera, F. Acerbi, A. Bahgat Shehata, and F. Zappa, “Advanced single photon counting instrumentation for SPADs,” Proc. SPIE 7945, 79452O (2011).
[Crossref]

A. Tosi, A. Dalla Mora, F. Zappa, A. Gulinatti, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon counting technique widens dynamic range and speeds up acquisition time in time-resolved measurements,” Opt. Express 19(11), 10735–10746 (2011).
[Crossref] [PubMed]

A. Dalla Mora, A. Tosi, F. Zappa, S. Cova, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon avalanche diode for wide dynamic range near infrared spectroscopy,” Sel. Top. Quantum Electron. 16(4), 1023–1030 (2010).
[Crossref]

A. Pifferi, A. Torricelli, L. Spinelli, D. Contini, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, A. Dalla Mora, F. Zappa, and S. Cova, “Time-Resolved Diffuse Reflectance Using Small Source-Detector Separation and Fast Single-Photon Gating,” Phys. Rev. Lett. 100(13), 138101 (2008).
[Crossref] [PubMed]

Del Bianco, S.

A. Torricelli, A. Pifferi, L. Spinelli, R. Cubeddu, F. Martelli, S. Del Bianco, and G. Zaccanti, “Time-Resolved Reflectance at Null Source-Detector Separation: Improving Contrast and Resolution in Diffuse Optical Imaging,” Phys. Rev. Lett. 95(7), 078101 (2005).
[Crossref] [PubMed]

Della Frera, A.

G. Boso, A. Dalla Mora, A. Della Frera, and A. Tosi, “Fast-gating of single-photon avalanche diodes with 200 ps transitions and 30 ps timing jitter,” Sens. Actuators A Phys. 191, 61–67 (2013).
[Crossref]

A. Tosi, A. Dalla Mora, A. Della Frera, F. Acerbi, A. Bahgat Shehata, and F. Zappa, “Advanced single photon counting instrumentation for SPADs,” Proc. SPIE 7945, 79452O (2011).
[Crossref]

Delpy, D. T.

D. T. Delpy and M. Cope, “Quantification in tissue near-infrared spectroscopy uantification in tissue near-infrared spectroscopy,” 352, 649 (1997).

Di Ninni, P.

F. Martelli, P. Di Ninni, G. Zaccanti, D. Contini, L. Spinelli, A. Torricelli, R. Cubeddu, H. Wabnitz, M. Mazurenka, R. Macdonald, A. Sassaroli, and A. Pifferi, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: experimental implementation,” J. Biomed. Opt. 19(7), 076011 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

A. Sassaroli, A. Pifferi, D. Contini, A. Torricelli, L. Spinelli, H. Wabnitz, P. Di Ninni, G. Zaccanti, and F. Martelli, “Forward solvers for photon migration in the presence of highly and totally absorbing objects embedded inside diffusive media,” J. Opt. Soc. Am. A 31(3), 460–469 (2014).
[Crossref] [PubMed]

Di Sieno, L.

M. Renna, M. Buttafava, A. Behera, M. Zanoletti, L. Di Sieno, A. Dalla Mora, D. Contini, and A. Tosi, “Eight-wavelength, dual detection-channel instrument for near-infrared time-resolved diffuse optical spectroscopy,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1 (2019).

L. Di Sieno, J. Nissinen, L. Hallman, E. Martinenghi, D. Contini, A. Pifferi, J. Kostamovaara, and A. D. Mora, “Miniaturized pulsed laser source for time-domain diffuse optics routes to wearable devices,” J. Biomed. Opt. 22(8), 1–9 (2017).
[Crossref] [PubMed]

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

L. Di Sieno, H. Wabnitz, A. Pifferi, M. Mazurenka, Y. Hoshi, A. Dalla Mora, D. Contini, G. Boso, W. Becker, F. Martelli, A. Tosi, and R. Macdonald, “Characterization of a time-resolved non-contact scanning diffuse optical imaging system exploiting fast-gated single-photon avalanche diode detection,” Rev. Sci. Instrum. 87(3), 035118 (2016).
[Crossref] [PubMed]

A. Dalla Mora, A. Tosi, D. Contini, L. Di Sieno, G. Boso, F. Villa, and A. Pifferi, “Memory effect in silicon time-gated single-photon avalanche diodes,” J. Appl. Phys. 117(11), 114501 (2015).
[Crossref]

A. Puszka, L. Di Sieno, A. D. Mora, A. Pifferi, D. Contini, A. Planat-Chrétien, A. Koenig, G. Boso, A. Tosi, L. Hervé, and J.-M. Dinten, “Spatial resolution in depth for time-resolved diffuse optical tomography using short source-detector separations,” Biomed. Opt. Express 6(1), 1–10 (2015).
[Crossref] [PubMed]

Dinten, J.-M.

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

A. Puszka, L. Di Sieno, A. D. Mora, A. Pifferi, D. Contini, A. Planat-Chrétien, A. Koenig, G. Boso, A. Tosi, L. Hervé, and J.-M. Dinten, “Spatial resolution in depth for time-resolved diffuse optical tomography using short source-detector separations,” Biomed. Opt. Express 6(1), 1–10 (2015).
[Crossref] [PubMed]

Douek, M.

L. Enfield, G. Cantanhede, M. Douek, V. Ramalingam, A. Purushotham, J. Hebden, and A. Gibson, “Monitoring the response to neoadjuvant hormone therapy for locally advanced breast cancer using three-dimensional time-resolved optical mammography,” J. Biomed. Opt. 18(5), 056012 (2013).
[Crossref] [PubMed]

Durduran, T.

Elster, C.

Enfield, L.

L. Enfield, G. Cantanhede, M. Douek, V. Ramalingam, A. Purushotham, J. Hebden, and A. Gibson, “Monitoring the response to neoadjuvant hormone therapy for locally advanced breast cancer using three-dimensional time-resolved optical mammography,” J. Biomed. Opt. 18(5), 056012 (2013).
[Crossref] [PubMed]

Esposto, S.

A. Bellincontro, A. Taticchi, M. Servili, S. Esposto, D. Farinelli, and F. Mencarelli, “Feasible application of a portable nir-AOTF tool for on-field prediction of phenolic compounds during the ripening of olives for oil production,” J. Agric. Food Chem. 60(10), 2665–2673 (2012).
[Crossref] [PubMed]

Farina, A.

F. Martelli, T. Binzoni, A. Pifferi, L. Spinelli, A. Farina, and A. Torricelli, “There’s plenty of light at the bottom: statistics of photon penetration depth in random media,” Sci. Rep. 6(1), 27057 (2016).
[Crossref] [PubMed]

A. Pifferi, D. Contini, A. D. Mora, A. Farina, L. Spinelli, and A. Torricelli, “New frontiers in time-domain diffuse optics, a review,” J. Biomed. Opt. 21(9), 091310 (2016).
[Crossref] [PubMed]

D. Contini, A. Dalla Mora, L. Spinelli, A. Farina, A. Torricelli, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, G. Boso, F. Zappa, and A. Pifferi, “Effects of time-gated detection in diffuse optical imaging at short source-detector separation,” J. Phys. D Appl. Phys. 48(4), 045401 (2015).
[Crossref]

A. D. Mora, D. Contini, S. Arridge, F. Martelli, A. Tosi, G. Boso, A. Farina, T. Durduran, E. Martinenghi, A. Torricelli, and A. Pifferi, “Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity,” Biomed. Opt. Express 6(5), 1749–1760 (2015).
[Crossref] [PubMed]

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

I. Bargigia, A. Nevin, A. Farina, A. Pifferi, C. D’Andrea, M. Karlsson, P. Lundin, G. Somesfalean, and S. Svanberg, “Diffuse optical techniques applied to wood characterisation,” J. Near Infrared Spectrosc. 21(4), 259–268 (2013).
[Crossref]

Farinelli, D.

A. Bellincontro, A. Taticchi, M. Servili, S. Esposto, D. Farinelli, and F. Mencarelli, “Feasible application of a portable nir-AOTF tool for on-field prediction of phenolic compounds during the ripening of olives for oil production,” J. Agric. Food Chem. 60(10), 2665–2673 (2012).
[Crossref] [PubMed]

Ferrari, M.

M. Ferrari and V. Quaresima, “A brief review on the history of human functional near-infrared spectroscopy (fNIRS) development and fields of application,” Neuroimage 63(2), 921–935 (2012).
[Crossref] [PubMed]

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, “Mapping of calf muscle oxygenation and haemoglobin content during dynamic plantar flexion exercise by multi-channel time-resolved near-infrared spectroscopy,” Phys. Med. Biol. 49(5), 685–699 (2004).
[Crossref] [PubMed]

Foschum, F.

Gallant, P.

Giambattistelli, E.

A. Pifferi, A. Torricelli, P. Taroni, A. Bassi, E. Chikoidze, E. Giambattistelli, and R. Cubeddu, “Optical biopsy of bone tissue: a step toward the diagnosis of bone pathologies,” J. Biomed. Opt. 9(3), 474–480 (2004).
[Crossref] [PubMed]

Giammarco, J.

T. Durduran, R. Choe, J. P. Culver, L. Zubkov, M. J. Holboke, J. Giammarco, B. Chance, and A. G. Yodh, “Bulk optical properties of healthy female breast tissue,” Phys. Med. Biol. 47(16), 2847–2861 (2002).
[Crossref] [PubMed]

Gibson, A.

L. Enfield, G. Cantanhede, M. Douek, V. Ramalingam, A. Purushotham, J. Hebden, and A. Gibson, “Monitoring the response to neoadjuvant hormone therapy for locally advanced breast cancer using three-dimensional time-resolved optical mammography,” J. Biomed. Opt. 18(5), 056012 (2013).
[Crossref] [PubMed]

Grateau, H.

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

Gulinatti, A.

Hallman, L.

L. Di Sieno, J. Nissinen, L. Hallman, E. Martinenghi, D. Contini, A. Pifferi, J. Kostamovaara, and A. D. Mora, “Miniaturized pulsed laser source for time-domain diffuse optics routes to wearable devices,” J. Biomed. Opt. 22(8), 1–9 (2017).
[Crossref] [PubMed]

Hamou, C.

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

Hebden, J.

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

L. Enfield, G. Cantanhede, M. Douek, V. Ramalingam, A. Purushotham, J. Hebden, and A. Gibson, “Monitoring the response to neoadjuvant hormone therapy for locally advanced breast cancer using three-dimensional time-resolved optical mammography,” J. Biomed. Opt. 18(5), 056012 (2013).
[Crossref] [PubMed]

Hervé, L.

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

A. Puszka, L. Di Sieno, A. D. Mora, A. Pifferi, D. Contini, A. Planat-Chrétien, A. Koenig, G. Boso, A. Tosi, L. Hervé, and J.-M. Dinten, “Spatial resolution in depth for time-resolved diffuse optical tomography using short source-detector separations,” Biomed. Opt. Express 6(1), 1–10 (2015).
[Crossref] [PubMed]

Ho, H.-C.

Holboke, M. J.

T. Durduran, R. Choe, J. P. Culver, L. Zubkov, M. J. Holboke, J. Giammarco, B. Chance, and A. G. Yodh, “Bulk optical properties of healthy female breast tissue,” Phys. Med. Biol. 47(16), 2847–2861 (2002).
[Crossref] [PubMed]

Hoshi, Y.

L. Di Sieno, H. Wabnitz, A. Pifferi, M. Mazurenka, Y. Hoshi, A. Dalla Mora, D. Contini, G. Boso, W. Becker, F. Martelli, A. Tosi, and R. Macdonald, “Characterization of a time-resolved non-contact scanning diffuse optical imaging system exploiting fast-gated single-photon avalanche diode detection,” Rev. Sci. Instrum. 87(3), 035118 (2016).
[Crossref] [PubMed]

Ieva, F.

P. Taroni, G. Quarto, A. Pifferi, F. Ieva, A. M. Paganoni, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and R. Cubeddu, “Optical identification of subjects at high risk for developing breast cancer,” J. Biomed. Opt. 18(6), 060507 (2013).
[Crossref] [PubMed]

Jacques, S. L.

Jelzow, A.

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

Kacprzak, M.

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

Karlsson, M.

Khoptyar, D.

Kienle, A.

Klauenberg, K.

Kleiser, S.

F. Scholkmann, S. Kleiser, A. J. Metz, R. Zimmermann, J. Mata Pavia, U. Wolf, and M. Wolf, “A review on continuous wave functional near-infrared spectroscopy and imaging instrumentation and methodology,” Neuroimage 85(Pt 1), 6–27 (2014).
[Crossref] [PubMed]

Koenig, A.

Kostamovaara, J.

L. Di Sieno, J. Nissinen, L. Hallman, E. Martinenghi, D. Contini, A. Pifferi, J. Kostamovaara, and A. D. Mora, “Miniaturized pulsed laser source for time-domain diffuse optics routes to wearable devices,” J. Biomed. Opt. 22(8), 1–9 (2017).
[Crossref] [PubMed]

Leclair, S.

Lesage, F.

Liebert, A.

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

Lundin, P.

Macdonald, R.

L. Di Sieno, H. Wabnitz, A. Pifferi, M. Mazurenka, Y. Hoshi, A. Dalla Mora, D. Contini, G. Boso, W. Becker, F. Martelli, A. Tosi, and R. Macdonald, “Characterization of a time-resolved non-contact scanning diffuse optical imaging system exploiting fast-gated single-photon avalanche diode detection,” Rev. Sci. Instrum. 87(3), 035118 (2016).
[Crossref] [PubMed]

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

F. Martelli, P. Di Ninni, G. Zaccanti, D. Contini, L. Spinelli, A. Torricelli, R. Cubeddu, H. Wabnitz, M. Mazurenka, R. Macdonald, A. Sassaroli, and A. Pifferi, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: experimental implementation,” J. Biomed. Opt. 19(7), 076011 (2014).
[Crossref] [PubMed]

F. Martelli, A. Pifferi, D. Contini, L. Spinelli, A. Torricelli, H. Wabnitz, R. Macdonald, A. Sassaroli, and G. Zaccanti, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 1: Basic concepts,” J. Biomed. Opt. 18(6), 066014 (2013).
[Crossref] [PubMed]

Magazov, S.

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

Maniewski, R.

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

Martelli, F.

L. Di Sieno, H. Wabnitz, A. Pifferi, M. Mazurenka, Y. Hoshi, A. Dalla Mora, D. Contini, G. Boso, W. Becker, F. Martelli, A. Tosi, and R. Macdonald, “Characterization of a time-resolved non-contact scanning diffuse optical imaging system exploiting fast-gated single-photon avalanche diode detection,” Rev. Sci. Instrum. 87(3), 035118 (2016).
[Crossref] [PubMed]

F. Martelli, T. Binzoni, A. Pifferi, L. Spinelli, A. Farina, and A. Torricelli, “There’s plenty of light at the bottom: statistics of photon penetration depth in random media,” Sci. Rep. 6(1), 27057 (2016).
[Crossref] [PubMed]

D. Contini, A. Dalla Mora, L. Spinelli, A. Farina, A. Torricelli, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, G. Boso, F. Zappa, and A. Pifferi, “Effects of time-gated detection in diffuse optical imaging at short source-detector separation,” J. Phys. D Appl. Phys. 48(4), 045401 (2015).
[Crossref]

A. D. Mora, D. Contini, S. Arridge, F. Martelli, A. Tosi, G. Boso, A. Farina, T. Durduran, E. Martinenghi, A. Torricelli, and A. Pifferi, “Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity,” Biomed. Opt. Express 6(5), 1749–1760 (2015).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

F. Martelli, P. Di Ninni, G. Zaccanti, D. Contini, L. Spinelli, A. Torricelli, R. Cubeddu, H. Wabnitz, M. Mazurenka, R. Macdonald, A. Sassaroli, and A. Pifferi, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: experimental implementation,” J. Biomed. Opt. 19(7), 076011 (2014).
[Crossref] [PubMed]

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

A. Sassaroli, A. Pifferi, D. Contini, A. Torricelli, L. Spinelli, H. Wabnitz, P. Di Ninni, G. Zaccanti, and F. Martelli, “Forward solvers for photon migration in the presence of highly and totally absorbing objects embedded inside diffusive media,” J. Opt. Soc. Am. A 31(3), 460–469 (2014).
[Crossref] [PubMed]

F. Martelli, A. Pifferi, D. Contini, L. Spinelli, A. Torricelli, H. Wabnitz, R. Macdonald, A. Sassaroli, and G. Zaccanti, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 1: Basic concepts,” J. Biomed. Opt. 18(6), 066014 (2013).
[Crossref] [PubMed]

A. Pifferi, A. Torricelli, L. Spinelli, D. Contini, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, A. Dalla Mora, F. Zappa, and S. Cova, “Time-Resolved Diffuse Reflectance Using Small Source-Detector Separation and Fast Single-Photon Gating,” Phys. Rev. Lett. 100(13), 138101 (2008).
[Crossref] [PubMed]

A. Torricelli, A. Pifferi, L. Spinelli, R. Cubeddu, F. Martelli, S. Del Bianco, and G. Zaccanti, “Time-Resolved Reflectance at Null Source-Detector Separation: Improving Contrast and Resolution in Diffuse Optical Imaging,” Phys. Rev. Lett. 95(7), 078101 (2005).
[Crossref] [PubMed]

Martinenghi, E.

L. Di Sieno, J. Nissinen, L. Hallman, E. Martinenghi, D. Contini, A. Pifferi, J. Kostamovaara, and A. D. Mora, “Miniaturized pulsed laser source for time-domain diffuse optics routes to wearable devices,” J. Biomed. Opt. 22(8), 1–9 (2017).
[Crossref] [PubMed]

A. D. Mora, D. Contini, S. Arridge, F. Martelli, A. Tosi, G. Boso, A. Farina, T. Durduran, E. Martinenghi, A. Torricelli, and A. Pifferi, “Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity,” Biomed. Opt. Express 6(5), 1749–1760 (2015).
[Crossref] [PubMed]

Mata Pavia, J.

F. Scholkmann, S. Kleiser, A. J. Metz, R. Zimmermann, J. Mata Pavia, U. Wolf, and M. Wolf, “A review on continuous wave functional near-infrared spectroscopy and imaging instrumentation and methodology,” Neuroimage 85(Pt 1), 6–27 (2014).
[Crossref] [PubMed]

Mazurenka, M.

L. Di Sieno, H. Wabnitz, A. Pifferi, M. Mazurenka, Y. Hoshi, A. Dalla Mora, D. Contini, G. Boso, W. Becker, F. Martelli, A. Tosi, and R. Macdonald, “Characterization of a time-resolved non-contact scanning diffuse optical imaging system exploiting fast-gated single-photon avalanche diode detection,” Rev. Sci. Instrum. 87(3), 035118 (2016).
[Crossref] [PubMed]

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

F. Martelli, P. Di Ninni, G. Zaccanti, D. Contini, L. Spinelli, A. Torricelli, R. Cubeddu, H. Wabnitz, M. Mazurenka, R. Macdonald, A. Sassaroli, and A. Pifferi, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: experimental implementation,” J. Biomed. Opt. 19(7), 076011 (2014).
[Crossref] [PubMed]

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

Mencarelli, F.

A. Bellincontro, A. Taticchi, M. Servili, S. Esposto, D. Farinelli, and F. Mencarelli, “Feasible application of a portable nir-AOTF tool for on-field prediction of phenolic compounds during the ripening of olives for oil production,” J. Agric. Food Chem. 60(10), 2665–2673 (2012).
[Crossref] [PubMed]

Menna, S.

G. Quarto, L. Spinelli, A. Pifferi, A. Torricelli, R. Cubeddu, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and P. Taroni, “Estimate of tissue composition in malignant and benign breast lesions by time-domain optical mammography,” Biomed. Opt. Express 5(10), 3684–3698 (2014).
[Crossref] [PubMed]

P. Taroni, G. Quarto, A. Pifferi, F. Ieva, A. M. Paganoni, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and R. Cubeddu, “Optical identification of subjects at high risk for developing breast cancer,” J. Biomed. Opt. 18(6), 060507 (2013).
[Crossref] [PubMed]

Mermut, O.

Metz, A. J.

F. Scholkmann, S. Kleiser, A. J. Metz, R. Zimmermann, J. Mata Pavia, U. Wolf, and M. Wolf, “A review on continuous wave functional near-infrared spectroscopy and imaging instrumentation and methodology,” Neuroimage 85(Pt 1), 6–27 (2014).
[Crossref] [PubMed]

Milej, D.

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

Mora, A. D.

L. Di Sieno, J. Nissinen, L. Hallman, E. Martinenghi, D. Contini, A. Pifferi, J. Kostamovaara, and A. D. Mora, “Miniaturized pulsed laser source for time-domain diffuse optics routes to wearable devices,” J. Biomed. Opt. 22(8), 1–9 (2017).
[Crossref] [PubMed]

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

A. Pifferi, D. Contini, A. D. Mora, A. Farina, L. Spinelli, and A. Torricelli, “New frontiers in time-domain diffuse optics, a review,” J. Biomed. Opt. 21(9), 091310 (2016).
[Crossref] [PubMed]

A. D. Mora, D. Contini, S. Arridge, F. Martelli, A. Tosi, G. Boso, A. Farina, T. Durduran, E. Martinenghi, A. Torricelli, and A. Pifferi, “Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity,” Biomed. Opt. Express 6(5), 1749–1760 (2015).
[Crossref] [PubMed]

A. Puszka, L. Di Sieno, A. D. Mora, A. Pifferi, D. Contini, A. Planat-Chrétien, A. Koenig, G. Boso, A. Tosi, L. Hervé, and J.-M. Dinten, “Spatial resolution in depth for time-resolved diffuse optical tomography using short source-detector separations,” Biomed. Opt. Express 6(1), 1–10 (2015).
[Crossref] [PubMed]

L. D. Sieno, A. D. Mora, G. Boso, A. Tosi, A. Pifferi, R. Cubeddu, and D. Contini, “Diffuse optics using a dual window fast-gated counter,” Appl. Opt. 53(31), 7394–7401 (2014).
[Crossref] [PubMed]

Nevin, A.

Nissinen, J.

L. Di Sieno, J. Nissinen, L. Hallman, E. Martinenghi, D. Contini, A. Pifferi, J. Kostamovaara, and A. D. Mora, “Miniaturized pulsed laser source for time-domain diffuse optics routes to wearable devices,” J. Biomed. Opt. 22(8), 1–9 (2017).
[Crossref] [PubMed]

Noiseux, I.

Paganoni, A. M.

P. Taroni, G. Quarto, A. Pifferi, F. Ieva, A. M. Paganoni, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and R. Cubeddu, “Optical identification of subjects at high risk for developing breast cancer,” J. Biomed. Opt. 18(6), 060507 (2013).
[Crossref] [PubMed]

Pifferi, A.

L. Di Sieno, J. Nissinen, L. Hallman, E. Martinenghi, D. Contini, A. Pifferi, J. Kostamovaara, and A. D. Mora, “Miniaturized pulsed laser source for time-domain diffuse optics routes to wearable devices,” J. Biomed. Opt. 22(8), 1–9 (2017).
[Crossref] [PubMed]

F. Martelli, T. Binzoni, A. Pifferi, L. Spinelli, A. Farina, and A. Torricelli, “There’s plenty of light at the bottom: statistics of photon penetration depth in random media,” Sci. Rep. 6(1), 27057 (2016).
[Crossref] [PubMed]

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

A. Pifferi, D. Contini, A. D. Mora, A. Farina, L. Spinelli, and A. Torricelli, “New frontiers in time-domain diffuse optics, a review,” J. Biomed. Opt. 21(9), 091310 (2016).
[Crossref] [PubMed]

L. Di Sieno, H. Wabnitz, A. Pifferi, M. Mazurenka, Y. Hoshi, A. Dalla Mora, D. Contini, G. Boso, W. Becker, F. Martelli, A. Tosi, and R. Macdonald, “Characterization of a time-resolved non-contact scanning diffuse optical imaging system exploiting fast-gated single-photon avalanche diode detection,” Rev. Sci. Instrum. 87(3), 035118 (2016).
[Crossref] [PubMed]

A. Dalla Mora, A. Tosi, D. Contini, L. Di Sieno, G. Boso, F. Villa, and A. Pifferi, “Memory effect in silicon time-gated single-photon avalanche diodes,” J. Appl. Phys. 117(11), 114501 (2015).
[Crossref]

D. Contini, A. Dalla Mora, L. Spinelli, A. Farina, A. Torricelli, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, G. Boso, F. Zappa, and A. Pifferi, “Effects of time-gated detection in diffuse optical imaging at short source-detector separation,” J. Phys. D Appl. Phys. 48(4), 045401 (2015).
[Crossref]

A. D. Mora, D. Contini, S. Arridge, F. Martelli, A. Tosi, G. Boso, A. Farina, T. Durduran, E. Martinenghi, A. Torricelli, and A. Pifferi, “Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity,” Biomed. Opt. Express 6(5), 1749–1760 (2015).
[Crossref] [PubMed]

A. Puszka, L. Di Sieno, A. D. Mora, A. Pifferi, D. Contini, A. Planat-Chrétien, A. Koenig, G. Boso, A. Tosi, L. Hervé, and J.-M. Dinten, “Spatial resolution in depth for time-resolved diffuse optical tomography using short source-detector separations,” Biomed. Opt. Express 6(1), 1–10 (2015).
[Crossref] [PubMed]

A. Sassaroli, A. Pifferi, D. Contini, A. Torricelli, L. Spinelli, H. Wabnitz, P. Di Ninni, G. Zaccanti, and F. Martelli, “Forward solvers for photon migration in the presence of highly and totally absorbing objects embedded inside diffusive media,” J. Opt. Soc. Am. A 31(3), 460–469 (2014).
[Crossref] [PubMed]

G. Quarto, L. Spinelli, A. Pifferi, A. Torricelli, R. Cubeddu, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and P. Taroni, “Estimate of tissue composition in malignant and benign breast lesions by time-domain optical mammography,” Biomed. Opt. Express 5(10), 3684–3698 (2014).
[Crossref] [PubMed]

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

F. Martelli, P. Di Ninni, G. Zaccanti, D. Contini, L. Spinelli, A. Torricelli, R. Cubeddu, H. Wabnitz, M. Mazurenka, R. Macdonald, A. Sassaroli, and A. Pifferi, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: experimental implementation,” J. Biomed. Opt. 19(7), 076011 (2014).
[Crossref] [PubMed]

A. Torricelli, D. Contini, A. Pifferi, M. Caffini, R. Re, L. Zucchelli, and L. Spinelli, “Time domain functional NIRS imaging for human brain mapping,” Neuroimage 85(Pt 1), 28–50 (2014).
[Crossref] [PubMed]

L. D. Sieno, A. D. Mora, G. Boso, A. Tosi, A. Pifferi, R. Cubeddu, and D. Contini, “Diffuse optics using a dual window fast-gated counter,” Appl. Opt. 53(31), 7394–7401 (2014).
[Crossref] [PubMed]

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

I. Bargigia, A. Nevin, A. Farina, A. Pifferi, C. D’Andrea, M. Karlsson, P. Lundin, G. Somesfalean, and S. Svanberg, “Diffuse optical techniques applied to wood characterisation,” J. Near Infrared Spectrosc. 21(4), 259–268 (2013).
[Crossref]

P. Taroni, G. Quarto, A. Pifferi, F. Ieva, A. M. Paganoni, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and R. Cubeddu, “Optical identification of subjects at high risk for developing breast cancer,” J. Biomed. Opt. 18(6), 060507 (2013).
[Crossref] [PubMed]

F. Martelli, A. Pifferi, D. Contini, L. Spinelli, A. Torricelli, H. Wabnitz, R. Macdonald, A. Sassaroli, and G. Zaccanti, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 1: Basic concepts,” J. Biomed. Opt. 18(6), 066014 (2013).
[Crossref] [PubMed]

A. Dalla Mora, D. Contini, A. Pifferi, R. Cubeddu, A. Tosi, and F. Zappa, “Afterpulse-like noise limits dynamic range in time-gated applications of thin-junction silicon single-photon avalanche diode,” Appl. Phys. Lett. 100(24), 241111 (2012).
[Crossref]

D. Contini, L. Zucchelli, L. Spinelli, M. Caffini, R. Re, A. Pifferi, R. Cubeddu, and A. Torricelli, “Review: Brain and muscle near infrared spectroscopy/imaging techniques,” J. Near Infrared Spectrosc. 20(1), 15–27 (2012).
[Crossref]

E. Alerstam, T. Svensson, S. Andersson-Engels, L. Spinelli, D. Contini, A. Dalla Mora, A. Tosi, F. Zappa, and A. Pifferi, “Single-fiber diffuse optical time-of-flight spectroscopy,” Opt. Lett. 37(14), 2877–2879 (2012).
[Crossref] [PubMed]

A. Tosi, A. Dalla Mora, F. Zappa, A. Gulinatti, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon counting technique widens dynamic range and speeds up acquisition time in time-resolved measurements,” Opt. Express 19(11), 10735–10746 (2011).
[Crossref] [PubMed]

A. Dalla Mora, A. Tosi, F. Zappa, S. Cova, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon avalanche diode for wide dynamic range near infrared spectroscopy,” Sel. Top. Quantum Electron. 16(4), 1023–1030 (2010).
[Crossref]

A. Pifferi, A. Torricelli, L. Spinelli, D. Contini, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, A. Dalla Mora, F. Zappa, and S. Cova, “Time-Resolved Diffuse Reflectance Using Small Source-Detector Separation and Fast Single-Photon Gating,” Phys. Rev. Lett. 100(13), 138101 (2008).
[Crossref] [PubMed]

A. Torricelli, A. Pifferi, L. Spinelli, R. Cubeddu, F. Martelli, S. Del Bianco, and G. Zaccanti, “Time-Resolved Reflectance at Null Source-Detector Separation: Improving Contrast and Resolution in Diffuse Optical Imaging,” Phys. Rev. Lett. 95(7), 078101 (2005).
[Crossref] [PubMed]

A. Pifferi, A. Torricelli, P. Taroni, A. Bassi, E. Chikoidze, E. Giambattistelli, and R. Cubeddu, “Optical biopsy of bone tissue: a step toward the diagnosis of bone pathologies,” J. Biomed. Opt. 9(3), 474–480 (2004).
[Crossref] [PubMed]

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, “Mapping of calf muscle oxygenation and haemoglobin content during dynamic plantar flexion exercise by multi-channel time-resolved near-infrared spectroscopy,” Phys. Med. Biol. 49(5), 685–699 (2004).
[Crossref] [PubMed]

Planat-Chrétien, A.

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

A. Puszka, L. Di Sieno, A. D. Mora, A. Pifferi, D. Contini, A. Planat-Chrétien, A. Koenig, G. Boso, A. Tosi, L. Hervé, and J.-M. Dinten, “Spatial resolution in depth for time-resolved diffuse optical tomography using short source-detector separations,” Biomed. Opt. Express 6(1), 1–10 (2015).
[Crossref] [PubMed]

Purushotham, A.

L. Enfield, G. Cantanhede, M. Douek, V. Ramalingam, A. Purushotham, J. Hebden, and A. Gibson, “Monitoring the response to neoadjuvant hormone therapy for locally advanced breast cancer using three-dimensional time-resolved optical mammography,” J. Biomed. Opt. 18(5), 056012 (2013).
[Crossref] [PubMed]

Puszka, A.

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

A. Puszka, L. Di Sieno, A. D. Mora, A. Pifferi, D. Contini, A. Planat-Chrétien, A. Koenig, G. Boso, A. Tosi, L. Hervé, and J.-M. Dinten, “Spatial resolution in depth for time-resolved diffuse optical tomography using short source-detector separations,” Biomed. Opt. Express 6(1), 1–10 (2015).
[Crossref] [PubMed]

Quaresima, V.

M. Ferrari and V. Quaresima, “A brief review on the history of human functional near-infrared spectroscopy (fNIRS) development and fields of application,” Neuroimage 63(2), 921–935 (2012).
[Crossref] [PubMed]

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, “Mapping of calf muscle oxygenation and haemoglobin content during dynamic plantar flexion exercise by multi-channel time-resolved near-infrared spectroscopy,” Phys. Med. Biol. 49(5), 685–699 (2004).
[Crossref] [PubMed]

Quarto, G.

G. Quarto, L. Spinelli, A. Pifferi, A. Torricelli, R. Cubeddu, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and P. Taroni, “Estimate of tissue composition in malignant and benign breast lesions by time-domain optical mammography,” Biomed. Opt. Express 5(10), 3684–3698 (2014).
[Crossref] [PubMed]

P. Taroni, G. Quarto, A. Pifferi, F. Ieva, A. M. Paganoni, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and R. Cubeddu, “Optical identification of subjects at high risk for developing breast cancer,” J. Biomed. Opt. 18(6), 060507 (2013).
[Crossref] [PubMed]

Ramalingam, V.

L. Enfield, G. Cantanhede, M. Douek, V. Ramalingam, A. Purushotham, J. Hebden, and A. Gibson, “Monitoring the response to neoadjuvant hormone therapy for locally advanced breast cancer using three-dimensional time-resolved optical mammography,” J. Biomed. Opt. 18(5), 056012 (2013).
[Crossref] [PubMed]

Re, R.

A. Torricelli, D. Contini, A. Pifferi, M. Caffini, R. Re, L. Zucchelli, and L. Spinelli, “Time domain functional NIRS imaging for human brain mapping,” Neuroimage 85(Pt 1), 28–50 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

D. Contini, L. Zucchelli, L. Spinelli, M. Caffini, R. Re, A. Pifferi, R. Cubeddu, and A. Torricelli, “Review: Brain and muscle near infrared spectroscopy/imaging techniques,” J. Near Infrared Spectrosc. 20(1), 15–27 (2012).
[Crossref]

Renna, M.

M. Renna, M. Buttafava, A. Behera, M. Zanoletti, L. Di Sieno, A. Dalla Mora, D. Contini, and A. Tosi, “Eight-wavelength, dual detection-channel instrument for near-infrared time-resolved diffuse optical spectroscopy,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1 (2019).

Sassaroli, A.

F. Martelli, P. Di Ninni, G. Zaccanti, D. Contini, L. Spinelli, A. Torricelli, R. Cubeddu, H. Wabnitz, M. Mazurenka, R. Macdonald, A. Sassaroli, and A. Pifferi, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: experimental implementation,” J. Biomed. Opt. 19(7), 076011 (2014).
[Crossref] [PubMed]

A. Sassaroli, A. Pifferi, D. Contini, A. Torricelli, L. Spinelli, H. Wabnitz, P. Di Ninni, G. Zaccanti, and F. Martelli, “Forward solvers for photon migration in the presence of highly and totally absorbing objects embedded inside diffusive media,” J. Opt. Soc. Am. A 31(3), 460–469 (2014).
[Crossref] [PubMed]

F. Martelli, A. Pifferi, D. Contini, L. Spinelli, A. Torricelli, H. Wabnitz, R. Macdonald, A. Sassaroli, and G. Zaccanti, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 1: Basic concepts,” J. Biomed. Opt. 18(6), 066014 (2013).
[Crossref] [PubMed]

Sawosz, P.

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

Scholkmann, F.

F. Scholkmann, S. Kleiser, A. J. Metz, R. Zimmermann, J. Mata Pavia, U. Wolf, and M. Wolf, “A review on continuous wave functional near-infrared spectroscopy and imaging instrumentation and methodology,” Neuroimage 85(Pt 1), 6–27 (2014).
[Crossref] [PubMed]

Servili, M.

A. Bellincontro, A. Taticchi, M. Servili, S. Esposto, D. Farinelli, and F. Mencarelli, “Feasible application of a portable nir-AOTF tool for on-field prediction of phenolic compounds during the ripening of olives for oil production,” J. Agric. Food Chem. 60(10), 2665–2673 (2012).
[Crossref] [PubMed]

Sieno, L. D.

Somesfalean, G.

Spinelli, L.

F. Martelli, T. Binzoni, A. Pifferi, L. Spinelli, A. Farina, and A. Torricelli, “There’s plenty of light at the bottom: statistics of photon penetration depth in random media,” Sci. Rep. 6(1), 27057 (2016).
[Crossref] [PubMed]

A. Pifferi, D. Contini, A. D. Mora, A. Farina, L. Spinelli, and A. Torricelli, “New frontiers in time-domain diffuse optics, a review,” J. Biomed. Opt. 21(9), 091310 (2016).
[Crossref] [PubMed]

D. Contini, A. Dalla Mora, L. Spinelli, A. Farina, A. Torricelli, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, G. Boso, F. Zappa, and A. Pifferi, “Effects of time-gated detection in diffuse optical imaging at short source-detector separation,” J. Phys. D Appl. Phys. 48(4), 045401 (2015).
[Crossref]

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

A. Torricelli, D. Contini, A. Pifferi, M. Caffini, R. Re, L. Zucchelli, and L. Spinelli, “Time domain functional NIRS imaging for human brain mapping,” Neuroimage 85(Pt 1), 28–50 (2014).
[Crossref] [PubMed]

F. Martelli, P. Di Ninni, G. Zaccanti, D. Contini, L. Spinelli, A. Torricelli, R. Cubeddu, H. Wabnitz, M. Mazurenka, R. Macdonald, A. Sassaroli, and A. Pifferi, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: experimental implementation,” J. Biomed. Opt. 19(7), 076011 (2014).
[Crossref] [PubMed]

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

G. Quarto, L. Spinelli, A. Pifferi, A. Torricelli, R. Cubeddu, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and P. Taroni, “Estimate of tissue composition in malignant and benign breast lesions by time-domain optical mammography,” Biomed. Opt. Express 5(10), 3684–3698 (2014).
[Crossref] [PubMed]

A. Sassaroli, A. Pifferi, D. Contini, A. Torricelli, L. Spinelli, H. Wabnitz, P. Di Ninni, G. Zaccanti, and F. Martelli, “Forward solvers for photon migration in the presence of highly and totally absorbing objects embedded inside diffusive media,” J. Opt. Soc. Am. A 31(3), 460–469 (2014).
[Crossref] [PubMed]

F. Martelli, A. Pifferi, D. Contini, L. Spinelli, A. Torricelli, H. Wabnitz, R. Macdonald, A. Sassaroli, and G. Zaccanti, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 1: Basic concepts,” J. Biomed. Opt. 18(6), 066014 (2013).
[Crossref] [PubMed]

D. Contini, L. Zucchelli, L. Spinelli, M. Caffini, R. Re, A. Pifferi, R. Cubeddu, and A. Torricelli, “Review: Brain and muscle near infrared spectroscopy/imaging techniques,” J. Near Infrared Spectrosc. 20(1), 15–27 (2012).
[Crossref]

E. Alerstam, T. Svensson, S. Andersson-Engels, L. Spinelli, D. Contini, A. Dalla Mora, A. Tosi, F. Zappa, and A. Pifferi, “Single-fiber diffuse optical time-of-flight spectroscopy,” Opt. Lett. 37(14), 2877–2879 (2012).
[Crossref] [PubMed]

A. Tosi, A. Dalla Mora, F. Zappa, A. Gulinatti, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon counting technique widens dynamic range and speeds up acquisition time in time-resolved measurements,” Opt. Express 19(11), 10735–10746 (2011).
[Crossref] [PubMed]

A. Dalla Mora, A. Tosi, F. Zappa, S. Cova, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon avalanche diode for wide dynamic range near infrared spectroscopy,” Sel. Top. Quantum Electron. 16(4), 1023–1030 (2010).
[Crossref]

A. Pifferi, A. Torricelli, L. Spinelli, D. Contini, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, A. Dalla Mora, F. Zappa, and S. Cova, “Time-Resolved Diffuse Reflectance Using Small Source-Detector Separation and Fast Single-Photon Gating,” Phys. Rev. Lett. 100(13), 138101 (2008).
[Crossref] [PubMed]

A. Torricelli, A. Pifferi, L. Spinelli, R. Cubeddu, F. Martelli, S. Del Bianco, and G. Zaccanti, “Time-Resolved Reflectance at Null Source-Detector Separation: Improving Contrast and Resolution in Diffuse Optical Imaging,” Phys. Rev. Lett. 95(7), 078101 (2005).
[Crossref] [PubMed]

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, “Mapping of calf muscle oxygenation and haemoglobin content during dynamic plantar flexion exercise by multi-channel time-resolved near-infrared spectroscopy,” Phys. Med. Biol. 49(5), 685–699 (2004).
[Crossref] [PubMed]

Steinkellner, O.

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

Subash, A. A.

Svanberg, S.

Svensson, T.

Taroni, P.

G. Quarto, L. Spinelli, A. Pifferi, A. Torricelli, R. Cubeddu, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and P. Taroni, “Estimate of tissue composition in malignant and benign breast lesions by time-domain optical mammography,” Biomed. Opt. Express 5(10), 3684–3698 (2014).
[Crossref] [PubMed]

P. Taroni, G. Quarto, A. Pifferi, F. Ieva, A. M. Paganoni, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and R. Cubeddu, “Optical identification of subjects at high risk for developing breast cancer,” J. Biomed. Opt. 18(6), 060507 (2013).
[Crossref] [PubMed]

A. Pifferi, A. Torricelli, P. Taroni, A. Bassi, E. Chikoidze, E. Giambattistelli, and R. Cubeddu, “Optical biopsy of bone tissue: a step toward the diagnosis of bone pathologies,” J. Biomed. Opt. 9(3), 474–480 (2004).
[Crossref] [PubMed]

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, “Mapping of calf muscle oxygenation and haemoglobin content during dynamic plantar flexion exercise by multi-channel time-resolved near-infrared spectroscopy,” Phys. Med. Biol. 49(5), 685–699 (2004).
[Crossref] [PubMed]

Taticchi, A.

A. Bellincontro, A. Taticchi, M. Servili, S. Esposto, D. Farinelli, and F. Mencarelli, “Feasible application of a portable nir-AOTF tool for on-field prediction of phenolic compounds during the ripening of olives for oil production,” J. Agric. Food Chem. 60(10), 2665–2673 (2012).
[Crossref] [PubMed]

Taubert, D. R.

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

Torricelli, A.

A. Pifferi, D. Contini, A. D. Mora, A. Farina, L. Spinelli, and A. Torricelli, “New frontiers in time-domain diffuse optics, a review,” J. Biomed. Opt. 21(9), 091310 (2016).
[Crossref] [PubMed]

F. Martelli, T. Binzoni, A. Pifferi, L. Spinelli, A. Farina, and A. Torricelli, “There’s plenty of light at the bottom: statistics of photon penetration depth in random media,” Sci. Rep. 6(1), 27057 (2016).
[Crossref] [PubMed]

D. Contini, A. Dalla Mora, L. Spinelli, A. Farina, A. Torricelli, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, G. Boso, F. Zappa, and A. Pifferi, “Effects of time-gated detection in diffuse optical imaging at short source-detector separation,” J. Phys. D Appl. Phys. 48(4), 045401 (2015).
[Crossref]

A. D. Mora, D. Contini, S. Arridge, F. Martelli, A. Tosi, G. Boso, A. Farina, T. Durduran, E. Martinenghi, A. Torricelli, and A. Pifferi, “Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity,” Biomed. Opt. Express 6(5), 1749–1760 (2015).
[Crossref] [PubMed]

G. Quarto, L. Spinelli, A. Pifferi, A. Torricelli, R. Cubeddu, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and P. Taroni, “Estimate of tissue composition in malignant and benign breast lesions by time-domain optical mammography,” Biomed. Opt. Express 5(10), 3684–3698 (2014).
[Crossref] [PubMed]

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

A. Torricelli, D. Contini, A. Pifferi, M. Caffini, R. Re, L. Zucchelli, and L. Spinelli, “Time domain functional NIRS imaging for human brain mapping,” Neuroimage 85(Pt 1), 28–50 (2014).
[Crossref] [PubMed]

F. Martelli, P. Di Ninni, G. Zaccanti, D. Contini, L. Spinelli, A. Torricelli, R. Cubeddu, H. Wabnitz, M. Mazurenka, R. Macdonald, A. Sassaroli, and A. Pifferi, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: experimental implementation,” J. Biomed. Opt. 19(7), 076011 (2014).
[Crossref] [PubMed]

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

A. Sassaroli, A. Pifferi, D. Contini, A. Torricelli, L. Spinelli, H. Wabnitz, P. Di Ninni, G. Zaccanti, and F. Martelli, “Forward solvers for photon migration in the presence of highly and totally absorbing objects embedded inside diffusive media,” J. Opt. Soc. Am. A 31(3), 460–469 (2014).
[Crossref] [PubMed]

F. Martelli, A. Pifferi, D. Contini, L. Spinelli, A. Torricelli, H. Wabnitz, R. Macdonald, A. Sassaroli, and G. Zaccanti, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 1: Basic concepts,” J. Biomed. Opt. 18(6), 066014 (2013).
[Crossref] [PubMed]

D. Contini, L. Zucchelli, L. Spinelli, M. Caffini, R. Re, A. Pifferi, R. Cubeddu, and A. Torricelli, “Review: Brain and muscle near infrared spectroscopy/imaging techniques,” J. Near Infrared Spectrosc. 20(1), 15–27 (2012).
[Crossref]

A. Tosi, A. Dalla Mora, F. Zappa, A. Gulinatti, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon counting technique widens dynamic range and speeds up acquisition time in time-resolved measurements,” Opt. Express 19(11), 10735–10746 (2011).
[Crossref] [PubMed]

A. Dalla Mora, A. Tosi, F. Zappa, S. Cova, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon avalanche diode for wide dynamic range near infrared spectroscopy,” Sel. Top. Quantum Electron. 16(4), 1023–1030 (2010).
[Crossref]

A. Pifferi, A. Torricelli, L. Spinelli, D. Contini, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, A. Dalla Mora, F. Zappa, and S. Cova, “Time-Resolved Diffuse Reflectance Using Small Source-Detector Separation and Fast Single-Photon Gating,” Phys. Rev. Lett. 100(13), 138101 (2008).
[Crossref] [PubMed]

A. Torricelli, A. Pifferi, L. Spinelli, R. Cubeddu, F. Martelli, S. Del Bianco, and G. Zaccanti, “Time-Resolved Reflectance at Null Source-Detector Separation: Improving Contrast and Resolution in Diffuse Optical Imaging,” Phys. Rev. Lett. 95(7), 078101 (2005).
[Crossref] [PubMed]

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, “Mapping of calf muscle oxygenation and haemoglobin content during dynamic plantar flexion exercise by multi-channel time-resolved near-infrared spectroscopy,” Phys. Med. Biol. 49(5), 685–699 (2004).
[Crossref] [PubMed]

A. Pifferi, A. Torricelli, P. Taroni, A. Bassi, E. Chikoidze, E. Giambattistelli, and R. Cubeddu, “Optical biopsy of bone tissue: a step toward the diagnosis of bone pathologies,” J. Biomed. Opt. 9(3), 474–480 (2004).
[Crossref] [PubMed]

Tosi, A.

M. Renna, M. Buttafava, A. Behera, M. Zanoletti, L. Di Sieno, A. Dalla Mora, D. Contini, and A. Tosi, “Eight-wavelength, dual detection-channel instrument for near-infrared time-resolved diffuse optical spectroscopy,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1 (2019).

L. Di Sieno, H. Wabnitz, A. Pifferi, M. Mazurenka, Y. Hoshi, A. Dalla Mora, D. Contini, G. Boso, W. Becker, F. Martelli, A. Tosi, and R. Macdonald, “Characterization of a time-resolved non-contact scanning diffuse optical imaging system exploiting fast-gated single-photon avalanche diode detection,” Rev. Sci. Instrum. 87(3), 035118 (2016).
[Crossref] [PubMed]

D. Contini, A. Dalla Mora, L. Spinelli, A. Farina, A. Torricelli, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, G. Boso, F. Zappa, and A. Pifferi, “Effects of time-gated detection in diffuse optical imaging at short source-detector separation,” J. Phys. D Appl. Phys. 48(4), 045401 (2015).
[Crossref]

A. Dalla Mora, A. Tosi, D. Contini, L. Di Sieno, G. Boso, F. Villa, and A. Pifferi, “Memory effect in silicon time-gated single-photon avalanche diodes,” J. Appl. Phys. 117(11), 114501 (2015).
[Crossref]

A. D. Mora, D. Contini, S. Arridge, F. Martelli, A. Tosi, G. Boso, A. Farina, T. Durduran, E. Martinenghi, A. Torricelli, and A. Pifferi, “Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity,” Biomed. Opt. Express 6(5), 1749–1760 (2015).
[Crossref] [PubMed]

A. Puszka, L. Di Sieno, A. D. Mora, A. Pifferi, D. Contini, A. Planat-Chrétien, A. Koenig, G. Boso, A. Tosi, L. Hervé, and J.-M. Dinten, “Spatial resolution in depth for time-resolved diffuse optical tomography using short source-detector separations,” Biomed. Opt. Express 6(1), 1–10 (2015).
[Crossref] [PubMed]

L. D. Sieno, A. D. Mora, G. Boso, A. Tosi, A. Pifferi, R. Cubeddu, and D. Contini, “Diffuse optics using a dual window fast-gated counter,” Appl. Opt. 53(31), 7394–7401 (2014).
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G. Boso, A. Dalla Mora, A. Della Frera, and A. Tosi, “Fast-gating of single-photon avalanche diodes with 200 ps transitions and 30 ps timing jitter,” Sens. Actuators A Phys. 191, 61–67 (2013).
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A. Dalla Mora, D. Contini, A. Pifferi, R. Cubeddu, A. Tosi, and F. Zappa, “Afterpulse-like noise limits dynamic range in time-gated applications of thin-junction silicon single-photon avalanche diode,” Appl. Phys. Lett. 100(24), 241111 (2012).
[Crossref]

E. Alerstam, T. Svensson, S. Andersson-Engels, L. Spinelli, D. Contini, A. Dalla Mora, A. Tosi, F. Zappa, and A. Pifferi, “Single-fiber diffuse optical time-of-flight spectroscopy,” Opt. Lett. 37(14), 2877–2879 (2012).
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A. Tosi, A. Dalla Mora, A. Della Frera, F. Acerbi, A. Bahgat Shehata, and F. Zappa, “Advanced single photon counting instrumentation for SPADs,” Proc. SPIE 7945, 79452O (2011).
[Crossref]

A. Tosi, A. Dalla Mora, F. Zappa, A. Gulinatti, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon counting technique widens dynamic range and speeds up acquisition time in time-resolved measurements,” Opt. Express 19(11), 10735–10746 (2011).
[Crossref] [PubMed]

A. Dalla Mora, A. Tosi, F. Zappa, S. Cova, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon avalanche diode for wide dynamic range near infrared spectroscopy,” Sel. Top. Quantum Electron. 16(4), 1023–1030 (2010).
[Crossref]

A. Pifferi, A. Torricelli, L. Spinelli, D. Contini, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, A. Dalla Mora, F. Zappa, and S. Cova, “Time-Resolved Diffuse Reflectance Using Small Source-Detector Separation and Fast Single-Photon Gating,” Phys. Rev. Lett. 100(13), 138101 (2008).
[Crossref] [PubMed]

Villa, F.

A. Dalla Mora, A. Tosi, D. Contini, L. Di Sieno, G. Boso, F. Villa, and A. Pifferi, “Memory effect in silicon time-gated single-photon avalanche diodes,” J. Appl. Phys. 117(11), 114501 (2015).
[Crossref]

Wabnitz, H.

L. Di Sieno, H. Wabnitz, A. Pifferi, M. Mazurenka, Y. Hoshi, A. Dalla Mora, D. Contini, G. Boso, W. Becker, F. Martelli, A. Tosi, and R. Macdonald, “Characterization of a time-resolved non-contact scanning diffuse optical imaging system exploiting fast-gated single-photon avalanche diode detection,” Rev. Sci. Instrum. 87(3), 035118 (2016).
[Crossref] [PubMed]

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

F. Martelli, P. Di Ninni, G. Zaccanti, D. Contini, L. Spinelli, A. Torricelli, R. Cubeddu, H. Wabnitz, M. Mazurenka, R. Macdonald, A. Sassaroli, and A. Pifferi, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: experimental implementation,” J. Biomed. Opt. 19(7), 076011 (2014).
[Crossref] [PubMed]

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

A. Sassaroli, A. Pifferi, D. Contini, A. Torricelli, L. Spinelli, H. Wabnitz, P. Di Ninni, G. Zaccanti, and F. Martelli, “Forward solvers for photon migration in the presence of highly and totally absorbing objects embedded inside diffusive media,” J. Opt. Soc. Am. A 31(3), 460–469 (2014).
[Crossref] [PubMed]

F. Martelli, A. Pifferi, D. Contini, L. Spinelli, A. Torricelli, H. Wabnitz, R. Macdonald, A. Sassaroli, and G. Zaccanti, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 1: Basic concepts,” J. Biomed. Opt. 18(6), 066014 (2013).
[Crossref] [PubMed]

Weigel, U.

Wolf, M.

F. Scholkmann, S. Kleiser, A. J. Metz, R. Zimmermann, J. Mata Pavia, U. Wolf, and M. Wolf, “A review on continuous wave functional near-infrared spectroscopy and imaging instrumentation and methodology,” Neuroimage 85(Pt 1), 6–27 (2014).
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Wolf, U.

F. Scholkmann, S. Kleiser, A. J. Metz, R. Zimmermann, J. Mata Pavia, U. Wolf, and M. Wolf, “A review on continuous wave functional near-infrared spectroscopy and imaging instrumentation and methodology,” Neuroimage 85(Pt 1), 6–27 (2014).
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A. Yodh and B. Chance, “Spectroscopy and imaging with diffusing light,” Phys. Today 48(3), 34–41 (1995).
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Yodh, A. G.

T. Durduran, R. Choe, W. B. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010).
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T. Durduran, R. Choe, J. P. Culver, L. Zubkov, M. J. Holboke, J. Giammarco, B. Chance, and A. G. Yodh, “Bulk optical properties of healthy female breast tissue,” Phys. Med. Biol. 47(16), 2847–2861 (2002).
[Crossref] [PubMed]

Zaccanti, G.

D. Contini, A. Dalla Mora, L. Spinelli, A. Farina, A. Torricelli, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, G. Boso, F. Zappa, and A. Pifferi, “Effects of time-gated detection in diffuse optical imaging at short source-detector separation,” J. Phys. D Appl. Phys. 48(4), 045401 (2015).
[Crossref]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

F. Martelli, P. Di Ninni, G. Zaccanti, D. Contini, L. Spinelli, A. Torricelli, R. Cubeddu, H. Wabnitz, M. Mazurenka, R. Macdonald, A. Sassaroli, and A. Pifferi, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: experimental implementation,” J. Biomed. Opt. 19(7), 076011 (2014).
[Crossref] [PubMed]

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

A. Sassaroli, A. Pifferi, D. Contini, A. Torricelli, L. Spinelli, H. Wabnitz, P. Di Ninni, G. Zaccanti, and F. Martelli, “Forward solvers for photon migration in the presence of highly and totally absorbing objects embedded inside diffusive media,” J. Opt. Soc. Am. A 31(3), 460–469 (2014).
[Crossref] [PubMed]

F. Martelli, A. Pifferi, D. Contini, L. Spinelli, A. Torricelli, H. Wabnitz, R. Macdonald, A. Sassaroli, and G. Zaccanti, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 1: Basic concepts,” J. Biomed. Opt. 18(6), 066014 (2013).
[Crossref] [PubMed]

A. Pifferi, A. Torricelli, L. Spinelli, D. Contini, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, A. Dalla Mora, F. Zappa, and S. Cova, “Time-Resolved Diffuse Reflectance Using Small Source-Detector Separation and Fast Single-Photon Gating,” Phys. Rev. Lett. 100(13), 138101 (2008).
[Crossref] [PubMed]

A. Torricelli, A. Pifferi, L. Spinelli, R. Cubeddu, F. Martelli, S. Del Bianco, and G. Zaccanti, “Time-Resolved Reflectance at Null Source-Detector Separation: Improving Contrast and Resolution in Diffuse Optical Imaging,” Phys. Rev. Lett. 95(7), 078101 (2005).
[Crossref] [PubMed]

Zanoletti, M.

M. Renna, M. Buttafava, A. Behera, M. Zanoletti, L. Di Sieno, A. Dalla Mora, D. Contini, and A. Tosi, “Eight-wavelength, dual detection-channel instrument for near-infrared time-resolved diffuse optical spectroscopy,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1 (2019).

Zappa, F.

D. Contini, A. Dalla Mora, L. Spinelli, A. Farina, A. Torricelli, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, G. Boso, F. Zappa, and A. Pifferi, “Effects of time-gated detection in diffuse optical imaging at short source-detector separation,” J. Phys. D Appl. Phys. 48(4), 045401 (2015).
[Crossref]

A. Dalla Mora, D. Contini, A. Pifferi, R. Cubeddu, A. Tosi, and F. Zappa, “Afterpulse-like noise limits dynamic range in time-gated applications of thin-junction silicon single-photon avalanche diode,” Appl. Phys. Lett. 100(24), 241111 (2012).
[Crossref]

E. Alerstam, T. Svensson, S. Andersson-Engels, L. Spinelli, D. Contini, A. Dalla Mora, A. Tosi, F. Zappa, and A. Pifferi, “Single-fiber diffuse optical time-of-flight spectroscopy,” Opt. Lett. 37(14), 2877–2879 (2012).
[Crossref] [PubMed]

A. Tosi, A. Dalla Mora, A. Della Frera, F. Acerbi, A. Bahgat Shehata, and F. Zappa, “Advanced single photon counting instrumentation for SPADs,” Proc. SPIE 7945, 79452O (2011).
[Crossref]

A. Tosi, A. Dalla Mora, F. Zappa, A. Gulinatti, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon counting technique widens dynamic range and speeds up acquisition time in time-resolved measurements,” Opt. Express 19(11), 10735–10746 (2011).
[Crossref] [PubMed]

A. Dalla Mora, A. Tosi, F. Zappa, S. Cova, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon avalanche diode for wide dynamic range near infrared spectroscopy,” Sel. Top. Quantum Electron. 16(4), 1023–1030 (2010).
[Crossref]

A. Pifferi, A. Torricelli, L. Spinelli, D. Contini, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, A. Dalla Mora, F. Zappa, and S. Cova, “Time-Resolved Diffuse Reflectance Using Small Source-Detector Separation and Fast Single-Photon Gating,” Phys. Rev. Lett. 100(13), 138101 (2008).
[Crossref] [PubMed]

Zimmermann, R.

F. Scholkmann, S. Kleiser, A. J. Metz, R. Zimmermann, J. Mata Pavia, U. Wolf, and M. Wolf, “A review on continuous wave functional near-infrared spectroscopy and imaging instrumentation and methodology,” Neuroimage 85(Pt 1), 6–27 (2014).
[Crossref] [PubMed]

Zolek, N.

Zubkov, L.

T. Durduran, R. Choe, J. P. Culver, L. Zubkov, M. J. Holboke, J. Giammarco, B. Chance, and A. G. Yodh, “Bulk optical properties of healthy female breast tissue,” Phys. Med. Biol. 47(16), 2847–2861 (2002).
[Crossref] [PubMed]

Zucchelli, L.

A. Torricelli, D. Contini, A. Pifferi, M. Caffini, R. Re, L. Zucchelli, and L. Spinelli, “Time domain functional NIRS imaging for human brain mapping,” Neuroimage 85(Pt 1), 28–50 (2014).
[Crossref] [PubMed]

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

D. Contini, L. Zucchelli, L. Spinelli, M. Caffini, R. Re, A. Pifferi, R. Cubeddu, and A. Torricelli, “Review: Brain and muscle near infrared spectroscopy/imaging techniques,” J. Near Infrared Spectrosc. 20(1), 15–27 (2012).
[Crossref]

Appl. Opt. (2)

Appl. Phys. Lett. (1)

A. Dalla Mora, D. Contini, A. Pifferi, R. Cubeddu, A. Tosi, and F. Zappa, “Afterpulse-like noise limits dynamic range in time-gated applications of thin-junction silicon single-photon avalanche diode,” Appl. Phys. Lett. 100(24), 241111 (2012).
[Crossref]

Biomed. Opt. Express (4)

A. Puszka, L. Di Sieno, A. D. Mora, A. Pifferi, D. Contini, A. Planat-Chrétien, A. Koenig, G. Boso, A. Tosi, L. Hervé, and J.-M. Dinten, “Spatial resolution in depth for time-resolved diffuse optical tomography using short source-detector separations,” Biomed. Opt. Express 6(1), 1–10 (2015).
[Crossref] [PubMed]

A. D. Mora, D. Contini, S. Arridge, F. Martelli, A. Tosi, G. Boso, A. Farina, T. Durduran, E. Martinenghi, A. Torricelli, and A. Pifferi, “Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity,” Biomed. Opt. Express 6(5), 1749–1760 (2015).
[Crossref] [PubMed]

L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli, R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, and G. Zaccanti, “Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink,” Biomed. Opt. Express 5(7), 2037–2053 (2014).
[Crossref] [PubMed]

G. Quarto, L. Spinelli, A. Pifferi, A. Torricelli, R. Cubeddu, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and P. Taroni, “Estimate of tissue composition in malignant and benign breast lesions by time-domain optical mammography,” Biomed. Opt. Express 5(10), 3684–3698 (2014).
[Crossref] [PubMed]

IEEE J. Sel. Top. Quantum Electron. (1)

M. Renna, M. Buttafava, A. Behera, M. Zanoletti, L. Di Sieno, A. Dalla Mora, D. Contini, and A. Tosi, “Eight-wavelength, dual detection-channel instrument for near-infrared time-resolved diffuse optical spectroscopy,” IEEE J. Sel. Top. Quantum Electron. 25(1), 1 (2019).

J. Agric. Food Chem. (1)

A. Bellincontro, A. Taticchi, M. Servili, S. Esposto, D. Farinelli, and F. Mencarelli, “Feasible application of a portable nir-AOTF tool for on-field prediction of phenolic compounds during the ripening of olives for oil production,” J. Agric. Food Chem. 60(10), 2665–2673 (2012).
[Crossref] [PubMed]

J. Appl. Phys. (1)

A. Dalla Mora, A. Tosi, D. Contini, L. Di Sieno, G. Boso, F. Villa, and A. Pifferi, “Memory effect in silicon time-gated single-photon avalanche diodes,” J. Appl. Phys. 117(11), 114501 (2015).
[Crossref]

J. Biomed. Opt. (10)

H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald, D. Milej, N. Żołek, M. Kacprzak, P. Sawosz, R. Maniewski, A. Liebert, S. Magazov, J. Hebden, F. Martelli, P. Di Ninni, G. Zaccanti, A. Torricelli, D. Contini, R. Re, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Pifferi, “Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol,” J. Biomed. Opt. 19(8), 086012 (2014).
[Crossref] [PubMed]

A. Pifferi, D. Contini, A. D. Mora, A. Farina, L. Spinelli, and A. Torricelli, “New frontiers in time-domain diffuse optics, a review,” J. Biomed. Opt. 21(9), 091310 (2016).
[Crossref] [PubMed]

H. Wabnitz, D. R. Taubert, M. Mazurenka, O. Steinkellner, A. Jelzow, R. Macdonald, D. Milej, P. Sawosz, M. Kacprzak, A. Liebert, R. Cooper, J. Hebden, A. Pifferi, A. Farina, I. Bargigia, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu, and A. Torricelli, “Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol,” J. Biomed. Opt. 19(8), 086010 (2014).
[Crossref] [PubMed]

F. Martelli, A. Pifferi, D. Contini, L. Spinelli, A. Torricelli, H. Wabnitz, R. Macdonald, A. Sassaroli, and G. Zaccanti, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 1: Basic concepts,” J. Biomed. Opt. 18(6), 066014 (2013).
[Crossref] [PubMed]

F. Martelli, P. Di Ninni, G. Zaccanti, D. Contini, L. Spinelli, A. Torricelli, R. Cubeddu, H. Wabnitz, M. Mazurenka, R. Macdonald, A. Sassaroli, and A. Pifferi, “Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: experimental implementation,” J. Biomed. Opt. 19(7), 076011 (2014).
[Crossref] [PubMed]

P. Taroni, G. Quarto, A. Pifferi, F. Ieva, A. M. Paganoni, F. Abbate, N. Balestreri, S. Menna, E. Cassano, and R. Cubeddu, “Optical identification of subjects at high risk for developing breast cancer,” J. Biomed. Opt. 18(6), 060507 (2013).
[Crossref] [PubMed]

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. D. Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, and A. Planat-Chrétien, “Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats,” J. Biomed. Opt. 21(2), 025004 (2016).
[Crossref] [PubMed]

A. Pifferi, A. Torricelli, P. Taroni, A. Bassi, E. Chikoidze, E. Giambattistelli, and R. Cubeddu, “Optical biopsy of bone tissue: a step toward the diagnosis of bone pathologies,” J. Biomed. Opt. 9(3), 474–480 (2004).
[Crossref] [PubMed]

L. Enfield, G. Cantanhede, M. Douek, V. Ramalingam, A. Purushotham, J. Hebden, and A. Gibson, “Monitoring the response to neoadjuvant hormone therapy for locally advanced breast cancer using three-dimensional time-resolved optical mammography,” J. Biomed. Opt. 18(5), 056012 (2013).
[Crossref] [PubMed]

L. Di Sieno, J. Nissinen, L. Hallman, E. Martinenghi, D. Contini, A. Pifferi, J. Kostamovaara, and A. D. Mora, “Miniaturized pulsed laser source for time-domain diffuse optics routes to wearable devices,” J. Biomed. Opt. 22(8), 1–9 (2017).
[Crossref] [PubMed]

J. Near Infrared Spectrosc. (2)

J. Opt. Soc. Am. A (1)

J. Phys. D Appl. Phys. (1)

D. Contini, A. Dalla Mora, L. Spinelli, A. Farina, A. Torricelli, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, G. Boso, F. Zappa, and A. Pifferi, “Effects of time-gated detection in diffuse optical imaging at short source-detector separation,” J. Phys. D Appl. Phys. 48(4), 045401 (2015).
[Crossref]

Neuroimage (3)

F. Scholkmann, S. Kleiser, A. J. Metz, R. Zimmermann, J. Mata Pavia, U. Wolf, and M. Wolf, “A review on continuous wave functional near-infrared spectroscopy and imaging instrumentation and methodology,” Neuroimage 85(Pt 1), 6–27 (2014).
[Crossref] [PubMed]

A. Torricelli, D. Contini, A. Pifferi, M. Caffini, R. Re, L. Zucchelli, and L. Spinelli, “Time domain functional NIRS imaging for human brain mapping,” Neuroimage 85(Pt 1), 28–50 (2014).
[Crossref] [PubMed]

M. Ferrari and V. Quaresima, “A brief review on the history of human functional near-infrared spectroscopy (fNIRS) development and fields of application,” Neuroimage 63(2), 921–935 (2012).
[Crossref] [PubMed]

Opt. Express (1)

Opt. Lett. (1)

Phys. Med. Biol. (2)

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, “Mapping of calf muscle oxygenation and haemoglobin content during dynamic plantar flexion exercise by multi-channel time-resolved near-infrared spectroscopy,” Phys. Med. Biol. 49(5), 685–699 (2004).
[Crossref] [PubMed]

T. Durduran, R. Choe, J. P. Culver, L. Zubkov, M. J. Holboke, J. Giammarco, B. Chance, and A. G. Yodh, “Bulk optical properties of healthy female breast tissue,” Phys. Med. Biol. 47(16), 2847–2861 (2002).
[Crossref] [PubMed]

Phys. Rev. Lett. (2)

A. Torricelli, A. Pifferi, L. Spinelli, R. Cubeddu, F. Martelli, S. Del Bianco, and G. Zaccanti, “Time-Resolved Reflectance at Null Source-Detector Separation: Improving Contrast and Resolution in Diffuse Optical Imaging,” Phys. Rev. Lett. 95(7), 078101 (2005).
[Crossref] [PubMed]

A. Pifferi, A. Torricelli, L. Spinelli, D. Contini, R. Cubeddu, F. Martelli, G. Zaccanti, A. Tosi, A. Dalla Mora, F. Zappa, and S. Cova, “Time-Resolved Diffuse Reflectance Using Small Source-Detector Separation and Fast Single-Photon Gating,” Phys. Rev. Lett. 100(13), 138101 (2008).
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Phys. Today (1)

A. Yodh and B. Chance, “Spectroscopy and imaging with diffusing light,” Phys. Today 48(3), 34–41 (1995).
[Crossref]

Proc. SPIE (1)

A. Tosi, A. Dalla Mora, A. Della Frera, F. Acerbi, A. Bahgat Shehata, and F. Zappa, “Advanced single photon counting instrumentation for SPADs,” Proc. SPIE 7945, 79452O (2011).
[Crossref]

Rep. Prog. Phys. (1)

T. Durduran, R. Choe, W. B. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010).
[Crossref] [PubMed]

Rev. Sci. Instrum. (1)

L. Di Sieno, H. Wabnitz, A. Pifferi, M. Mazurenka, Y. Hoshi, A. Dalla Mora, D. Contini, G. Boso, W. Becker, F. Martelli, A. Tosi, and R. Macdonald, “Characterization of a time-resolved non-contact scanning diffuse optical imaging system exploiting fast-gated single-photon avalanche diode detection,” Rev. Sci. Instrum. 87(3), 035118 (2016).
[Crossref] [PubMed]

Sci. Rep. (1)

F. Martelli, T. Binzoni, A. Pifferi, L. Spinelli, A. Farina, and A. Torricelli, “There’s plenty of light at the bottom: statistics of photon penetration depth in random media,” Sci. Rep. 6(1), 27057 (2016).
[Crossref] [PubMed]

Sel. Top. Quantum Electron. (1)

A. Dalla Mora, A. Tosi, F. Zappa, S. Cova, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, and R. Cubeddu, “Fast-gated single-photon avalanche diode for wide dynamic range near infrared spectroscopy,” Sel. Top. Quantum Electron. 16(4), 1023–1030 (2010).
[Crossref]

Sens. Actuators A Phys. (1)

G. Boso, A. Dalla Mora, A. Della Frera, and A. Tosi, “Fast-gating of single-photon avalanche diodes with 200 ps transitions and 30 ps timing jitter,” Sens. Actuators A Phys. 191, 61–67 (2013).
[Crossref]

Other (12)

D. V. O’ Connor and D. Phillips, Time-Correlated Single Photon Counting (Academic Press, 1984).

Figshare, “Dependence of contrast and CNR on the IRF full-width at half-maximum (FWHM),” https://doi.org/10.6084/m9.figshare.6731279.

Figshare, “Dependence of contrast and CNR on the fast tail amplitude (A1),” https://doi.org/10.6084/m9.figshare.6736532.

Figshare, “Dependence of contrast and CNR on the fast tail slope (Tau1),” https://doi.org/10.6084/m9.figshare.6736547.

Figshare, “Dependence of contrast and CNR on the memory tail amplitude (A2),” https://doi.org/10.6084/m9.figshare.6736550.

Figshare, “Dependence of contrast and CNR on the average laser power (P),” https://doi.org/10.6084/m9.figshare.6736553.

Figshare, “Dependence of contrast and CNR on the optical responsivity (R),” https://doi.org/10.6084/m9.figshare.6736556.

Figshare, “Dependence of contrast and CNR on the dark count rate (DCR),” https://doi.org/10.6084/m9.figshare.6736559.

Figshare, “Dependence of contrast and CNR on the afterpulsing (AP),” https://doi.org/10.6084/m9.figshare.6736568.

Figshare, “Dependence of contrast and CNR on the acquisition time (Aqt),” https://doi.org/10.6084/m9.figshare.6736574.

Figshare, “Dependence of contrast and CNR on optical properties of background diffusive medium,” https://doi.org/10.6084/m9.figshare.6736547.

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Supplementary Material (10)

NameDescription
» Dataset 1       Dependence of contrast and CNR on the IRF full-width at half-maximum (FWHM)
» Dataset 2       Dependence of contrast and CNR on the fast tail amplitude (A1)
» Dataset 3       Dependence of contrast and CNR on the fast tail slope (Tau1)
» Dataset 4       Dependence of contrast and CNR on the memory tail amplitude (A2)
» Dataset 5       Dependence of contrast and CNR on the average laser power (P)
» Dataset 6       Dependence of contrast and CNR on the optical responsivity (R)
» Dataset 7       Dependence of contrast and CNR on the dark count rate (DCR)
» Dataset 8       Dependence of contrast and CNR on the afterpulsing (AP)
» Dataset 9       Dependence of contrast and CNR on the acquisition time (Aqt)
» Dataset 10       Dependence of contrast and CNR on optical properties of background diffusive medium

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Figures (7)

Fig. 1
Fig. 1 (a) Schematics of the experimental setup used for measurements (dashed line: electrical connections; solid lines: optical path) and (b) reconstructed IRF of the setup.
Fig. 2
Fig. 2 Plot of contrast vs time (colors represent different source-detector distances), with change in depth of inclusion (Z) along the rows and absorption perturbation (∆µa) along the columns. The experimental points are reported as stars, while the continuous curves correspond to simulated values.
Fig. 3
Fig. 3 Plot of CNR vs time (colors represent different source-detector distances), with change in depth of inclusion (Z) along the rows and absorption perturbation (∆µa) along the columns. The experimental points are reported as dots, while the continuous curves correspond to simulated values.
Fig. 4
Fig. 4 Plot of Contrast vs time, with change in depth of inclusion (Z) along the rows and diffusion tail slope (τ1) along the columns.
Fig. 5
Fig. 5 Plot of CNR vs time, with change in depth of inclusion (Z) along the rows and diffusion tail slope (τ1) along the columns.
Fig. 6
Fig. 6 Plot of Contrast vs time, with change in depth of inclusion (Z) along the rows and memory amplitude (A2) along the columns.
Fig. 7
Fig. 7 Plot of CNR vs time, with change in depth of inclusion (Z) along the rows and memory amplitude (A2) along the columns.

Tables (7)

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Table 1 List of the parameters used in simulations and default values.

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Table 2 Parameters analyzed in the simulation study and their impact on the contrast and CNR.

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Table 3 Percentage error between measurements and simulations computed for both contrast and CNR for the depth of the inclusion of 10 mm.

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Table 4 Percentage error between measurements and simulations computed for both contrast and CNR for the depth of the inclusion of 15 mm.

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Table 5 Percentage error between measurements and simulations computed for both contrast and CNR for the depth of the inclusion of 20 mm.

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Table 6 Percentage error between measurements and simulations computed for both contrast and CNR for the depth of the inclusion of 25 mm.

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Table 7 Percentage error between measurements and simulations computed for both contrast and CNR for the depth of the inclusion of 30 mm.

Equations (3)

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C( t g )=  N 0 ( t g )N( t g ) N 0 ( t g )
CNR( t g )=  N 0 ( t g )N( t g ) σ( N 0 ( t g ))
error (%)= 100* x ˜ x x ˜

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