Abstract

For prevention and accurate intervention planning, it is crucial to predict if lesions will progress towards cancer. In this study, we investigated the change in optical properties and vascular parameters to characterize skin tissue from mild photodamage to actinic keratosis (AK). Multi-wavelength spatial frequency domain imaging (SFDI) measurements were performed on three patients with clinically normal skin, as well as pre-cancerous actinic keratosis lesions. Our results indicate that there exist significant differences in both optical and vascular parameters between these patients, and that these parameters can be early biomarkers of neoplasia. Ultimately, clinicians can use this noninvasive approach for frequent monitoring of high-risk population.

© 2017 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Data-driven imaging of tissue inflammation using RGB-based hyperspectral reconstruction toward personal monitoring of dermatologic health

Taehoon Kim, Michelle A. Visbal-Onufrak, Raymond L. Konger, and Young L. Kim
Biomed. Opt. Express 8(11) 5282-5296 (2017)

Quantitative physiology and immunohistochemistry of oral lesions

Li-Tzu Lee, Po-Hsiung Chen, Chiou-Tuz Chang, John Wang, Yong-Kie Wong, and Hsing-Wen Wang
Biomed. Opt. Express 4(11) 2696-2709 (2013)

Diffuse reflectance spectroscopy detects increased hemoglobin concentration and decreased oxygenation during colon carcinogenesis from normal to malignant tumors

Hsing-Wen Wang, Jeng-Kai Jiang, Chi-Hung Lin, Jen-Kou Lin, Guang-Jie Huang, and Jia-Sin Yu
Opt. Express 17(4) 2805-2817 (2009)

References

  • View by:
  • |
  • |
  • |

  1. H. W. Rogers, M. A. Weinstock, S. R. Feldman, and B. M. Coldiron, “Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the U.S. Population, 2012,” JAMA Dermatol. 151(10), 1081–1086 (2015).
    [Crossref] [PubMed]
  2. C. Kim, J. Cheng, and O. R. Colegio, “Cutaneous squamous cell carcinomas in solid organ transplant recipients: emerging strategies for surveillance, staging, and treatment,” Semin. Oncol. 43(3), 390–394 (2016).
    [Crossref] [PubMed]
  3. R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
    [Crossref] [PubMed]
  4. S. T. Guenthner, R. M. Hurwitz, L. J. Buckel, and H. R. Gray, “Cutaneous squamous cell carcinomas consistently show histologic evidence of in situ changes: a clinicopathologic correlation,” J. Am. Acad. Dermatol. 41(3), 443–448 (1999).
    [Crossref] [PubMed]
  5. M. Rajadhyaksha, A. Marghoob, A. Rossi, A. C. Halpern, and K. S. Nehal, “Reflectance confocal microscopy of skin in vivo: From bench to bedside,” Lasers Surg. Med. 49(1), 7–19 (2017).
    [Crossref] [PubMed]
  6. A. Marneffe, M. Suppa, M. Miyamoto, V. Del Marmol, and M. Boone, “Validation of a diagnostic algorithm for the discrimination of actinic keratosis from normal skin and squamous cell carcinoma by means of high-definition optical coherence tomography,” Exp. Dermatol. 25(9), 684–687 (2016).
    [Crossref] [PubMed]
  7. J. Olsen, L. Themstrup, N. De Carvalho, M. Mogensen, G. Pellacani, and G. B. Jemec, “Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma,” Photodiagn. Photodyn. Ther. 16, 44–49 (2016).
    [Crossref] [PubMed]
  8. R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “A light emitting diode (LED) based spatial frequency domain imaging system for optimization of photodynamic therapy of nonmelanoma skin cancer: quantitative reflectance imaging,” Lasers Surg. Med. 45(4), 207–215 (2013).
    [Crossref] [PubMed]
  9. T. J. Muldoon, S. A. Burgess, B. R. Chen, D. Ratner, and E. M. Hillman, “Analysis of skin lesions using laminar optical tomography,” Biomed. Opt. Express 3(7), 1701–1712 (2012).
    [Crossref] [PubMed]
  10. M. S. Ozturk, C. W. Chen, R. Ji, L. Zhao, B. N. Nguyen, J. P. Fisher, Y. Chen, and X. Intes, “Mesoscopic Fluorescence Molecular Tomography for Evaluating Engineered Tissues,” Ann. Biomed. Eng. 44(3), 667–679 (2016).
    [Crossref] [PubMed]
  11. M. S. Ozturk, D. Rohrbach, U. Sunar, and X. Intes, “Mesoscopic fluorescence tomography of a photosensitizer (HPPH) 3D biodistribution in skin cancer,” Acad. Radiol. 21(2), 271–280 (2014).
    [Crossref] [PubMed]
  12. D. J. Cuccia, F. Bevilacqua, A. J. Durkin, F. R. Ayers, and B. J. Tromberg, “Quantitation and mapping of tissue optical properties using modulated imaging,” J. Biomed. Opt. 14(2), 024012 (2009).
    [Crossref] [PubMed]
  13. D. J. Cuccia, F. Bevilacqua, A. J. Durkin, and B. J. Tromberg, “Modulated imaging: quantitative analysis and tomography of turbid media in the spatial-frequency domain,” Opt. Lett. 30(11), 1354–1356 (2005).
    [Crossref] [PubMed]
  14. R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain,” J. Biomed. Opt. 16(12), 126013 (2011).
    [Crossref] [PubMed]
  15. U. Sunar, D. J. Rohrbach, J. Morgan, N. Zeitouni, and B. W. Henderson, “Quantification of PpIX concentration in basal cell carcinoma and squamous cell carcinoma models using spatial frequency domain imaging,” Biomed. Opt. Express 4(4), 531–537 (2013).
    [Crossref] [PubMed]
  16. R. L. Konger, Z. Xu, R. P. Sahu, B. M. Rashid, S. R. Mehta, D. R. Mohamed, S. C. DaSilva-Arnold, J. R. Bradish, S. J. Warren, and Y. L. Kim, “Spatiotemporal assessments of dermal hyperemia enable accurate prediction of experimental cutaneous carcinogenesis as well as chemopreventive activity,” Cancer Res. 73(1), 150–159 (2013).
    [Crossref] [PubMed]
  17. D. J. Rohrbach, D. Muffoletto, J. Huihui, R. Saager, K. Keymel, A. Paquette, J. Morgan, N. Zeitouni, and U. Sunar, “Preoperative mapping of nonmelanoma skin cancer using spatial frequency domain and ultrasound imaging,” Acad. Radiol. 21(2), 263–270 (2014).
    [Crossref] [PubMed]
  18. D. J. Rohrbach, N. C. Zeitouni, D. Muffoletto, R. Saager, B. J. Tromberg, and U. Sunar, “Characterization of nonmelanoma skin cancer for light therapy using spatial frequency domain imaging,” Biomed. Opt. Express 6(5), 1761–1766 (2015).
    [Crossref] [PubMed]
  19. N. E. McKenzie, K. Saboda, L. D. Duckett, R. Goldman, C. Hu, and C. N. Curiel-Lewandrowski, “Development of a photographic scale for consistency and guidance in dermatologic assessment of forearm sun damage,” Arch. Dermatol. 147(1), 31–36 (2011).
    [Crossref] [PubMed]
  20. N. Bodenschatz, A. Brandes, A. Liemert, and A. Kienle, “Sources of errors in spatial frequency domain imaging of scattering media,” J. Biomed. Opt. 19(7), 071405 (2014).
    [Crossref] [PubMed]
  21. J. R. Mourant, T. Fuselier, J. Boyer, T. M. Johnson, and I. J. Bigio, “Predictions and measurements of scattering and absorption over broad wavelength ranges in tissue phantoms,” Appl. Opt. 36(4), 949–957 (1997).
    [Crossref] [PubMed]
  22. R. B. Saager, A. Sharif, K. M. Kelly, and A. J. Durkin, “In vivo isolation of the effects of melanin from underlying hemodynamics across skin types using spatial frequency domain spectroscopy,” J. Biomed. Opt. 21(5), 057001 (2016).
    [Crossref] [PubMed]
  23. M. van de Giessen, J. P. Angelo, and S. Gioux, “Real-time, profile-corrected single snapshot imaging of optical properties,” Biomed. Opt. Express 6(10), 4051–4062 (2015).
    [Crossref] [PubMed]
  24. J. Angelo, C. R. Vargas, B. T. Lee, I. J. Bigio, and S. Gioux, “Ultrafast optical property map generation using lookup tables,” J. Biomed. Opt. 21(11), 110501 (2016).
    [Crossref] [PubMed]

2017 (1)

M. Rajadhyaksha, A. Marghoob, A. Rossi, A. C. Halpern, and K. S. Nehal, “Reflectance confocal microscopy of skin in vivo: From bench to bedside,” Lasers Surg. Med. 49(1), 7–19 (2017).
[Crossref] [PubMed]

2016 (6)

A. Marneffe, M. Suppa, M. Miyamoto, V. Del Marmol, and M. Boone, “Validation of a diagnostic algorithm for the discrimination of actinic keratosis from normal skin and squamous cell carcinoma by means of high-definition optical coherence tomography,” Exp. Dermatol. 25(9), 684–687 (2016).
[Crossref] [PubMed]

J. Olsen, L. Themstrup, N. De Carvalho, M. Mogensen, G. Pellacani, and G. B. Jemec, “Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma,” Photodiagn. Photodyn. Ther. 16, 44–49 (2016).
[Crossref] [PubMed]

C. Kim, J. Cheng, and O. R. Colegio, “Cutaneous squamous cell carcinomas in solid organ transplant recipients: emerging strategies for surveillance, staging, and treatment,” Semin. Oncol. 43(3), 390–394 (2016).
[Crossref] [PubMed]

M. S. Ozturk, C. W. Chen, R. Ji, L. Zhao, B. N. Nguyen, J. P. Fisher, Y. Chen, and X. Intes, “Mesoscopic Fluorescence Molecular Tomography for Evaluating Engineered Tissues,” Ann. Biomed. Eng. 44(3), 667–679 (2016).
[Crossref] [PubMed]

R. B. Saager, A. Sharif, K. M. Kelly, and A. J. Durkin, “In vivo isolation of the effects of melanin from underlying hemodynamics across skin types using spatial frequency domain spectroscopy,” J. Biomed. Opt. 21(5), 057001 (2016).
[Crossref] [PubMed]

J. Angelo, C. R. Vargas, B. T. Lee, I. J. Bigio, and S. Gioux, “Ultrafast optical property map generation using lookup tables,” J. Biomed. Opt. 21(11), 110501 (2016).
[Crossref] [PubMed]

2015 (4)

H. W. Rogers, M. A. Weinstock, S. R. Feldman, and B. M. Coldiron, “Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the U.S. Population, 2012,” JAMA Dermatol. 151(10), 1081–1086 (2015).
[Crossref] [PubMed]

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

D. J. Rohrbach, N. C. Zeitouni, D. Muffoletto, R. Saager, B. J. Tromberg, and U. Sunar, “Characterization of nonmelanoma skin cancer for light therapy using spatial frequency domain imaging,” Biomed. Opt. Express 6(5), 1761–1766 (2015).
[Crossref] [PubMed]

M. van de Giessen, J. P. Angelo, and S. Gioux, “Real-time, profile-corrected single snapshot imaging of optical properties,” Biomed. Opt. Express 6(10), 4051–4062 (2015).
[Crossref] [PubMed]

2014 (3)

M. S. Ozturk, D. Rohrbach, U. Sunar, and X. Intes, “Mesoscopic fluorescence tomography of a photosensitizer (HPPH) 3D biodistribution in skin cancer,” Acad. Radiol. 21(2), 271–280 (2014).
[Crossref] [PubMed]

D. J. Rohrbach, D. Muffoletto, J. Huihui, R. Saager, K. Keymel, A. Paquette, J. Morgan, N. Zeitouni, and U. Sunar, “Preoperative mapping of nonmelanoma skin cancer using spatial frequency domain and ultrasound imaging,” Acad. Radiol. 21(2), 263–270 (2014).
[Crossref] [PubMed]

N. Bodenschatz, A. Brandes, A. Liemert, and A. Kienle, “Sources of errors in spatial frequency domain imaging of scattering media,” J. Biomed. Opt. 19(7), 071405 (2014).
[Crossref] [PubMed]

2013 (3)

R. L. Konger, Z. Xu, R. P. Sahu, B. M. Rashid, S. R. Mehta, D. R. Mohamed, S. C. DaSilva-Arnold, J. R. Bradish, S. J. Warren, and Y. L. Kim, “Spatiotemporal assessments of dermal hyperemia enable accurate prediction of experimental cutaneous carcinogenesis as well as chemopreventive activity,” Cancer Res. 73(1), 150–159 (2013).
[Crossref] [PubMed]

R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “A light emitting diode (LED) based spatial frequency domain imaging system for optimization of photodynamic therapy of nonmelanoma skin cancer: quantitative reflectance imaging,” Lasers Surg. Med. 45(4), 207–215 (2013).
[Crossref] [PubMed]

U. Sunar, D. J. Rohrbach, J. Morgan, N. Zeitouni, and B. W. Henderson, “Quantification of PpIX concentration in basal cell carcinoma and squamous cell carcinoma models using spatial frequency domain imaging,” Biomed. Opt. Express 4(4), 531–537 (2013).
[Crossref] [PubMed]

2012 (1)

2011 (2)

N. E. McKenzie, K. Saboda, L. D. Duckett, R. Goldman, C. Hu, and C. N. Curiel-Lewandrowski, “Development of a photographic scale for consistency and guidance in dermatologic assessment of forearm sun damage,” Arch. Dermatol. 147(1), 31–36 (2011).
[Crossref] [PubMed]

R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain,” J. Biomed. Opt. 16(12), 126013 (2011).
[Crossref] [PubMed]

2009 (1)

D. J. Cuccia, F. Bevilacqua, A. J. Durkin, F. R. Ayers, and B. J. Tromberg, “Quantitation and mapping of tissue optical properties using modulated imaging,” J. Biomed. Opt. 14(2), 024012 (2009).
[Crossref] [PubMed]

2005 (1)

1999 (1)

S. T. Guenthner, R. M. Hurwitz, L. J. Buckel, and H. R. Gray, “Cutaneous squamous cell carcinomas consistently show histologic evidence of in situ changes: a clinicopathologic correlation,” J. Am. Acad. Dermatol. 41(3), 443–448 (1999).
[Crossref] [PubMed]

1997 (1)

Angelo, J.

J. Angelo, C. R. Vargas, B. T. Lee, I. J. Bigio, and S. Gioux, “Ultrafast optical property map generation using lookup tables,” J. Biomed. Opt. 21(11), 110501 (2016).
[Crossref] [PubMed]

Angelo, J. P.

Ayers, F. R.

D. J. Cuccia, F. Bevilacqua, A. J. Durkin, F. R. Ayers, and B. J. Tromberg, “Quantitation and mapping of tissue optical properties using modulated imaging,” J. Biomed. Opt. 14(2), 024012 (2009).
[Crossref] [PubMed]

Bevilacqua, F.

D. J. Cuccia, F. Bevilacqua, A. J. Durkin, F. R. Ayers, and B. J. Tromberg, “Quantitation and mapping of tissue optical properties using modulated imaging,” J. Biomed. Opt. 14(2), 024012 (2009).
[Crossref] [PubMed]

D. J. Cuccia, F. Bevilacqua, A. J. Durkin, and B. J. Tromberg, “Modulated imaging: quantitative analysis and tomography of turbid media in the spatial-frequency domain,” Opt. Lett. 30(11), 1354–1356 (2005).
[Crossref] [PubMed]

Bigio, I. J.

J. Angelo, C. R. Vargas, B. T. Lee, I. J. Bigio, and S. Gioux, “Ultrafast optical property map generation using lookup tables,” J. Biomed. Opt. 21(11), 110501 (2016).
[Crossref] [PubMed]

J. R. Mourant, T. Fuselier, J. Boyer, T. M. Johnson, and I. J. Bigio, “Predictions and measurements of scattering and absorption over broad wavelength ranges in tissue phantoms,” Appl. Opt. 36(4), 949–957 (1997).
[Crossref] [PubMed]

Bodenschatz, N.

N. Bodenschatz, A. Brandes, A. Liemert, and A. Kienle, “Sources of errors in spatial frequency domain imaging of scattering media,” J. Biomed. Opt. 19(7), 071405 (2014).
[Crossref] [PubMed]

Boone, M.

A. Marneffe, M. Suppa, M. Miyamoto, V. Del Marmol, and M. Boone, “Validation of a diagnostic algorithm for the discrimination of actinic keratosis from normal skin and squamous cell carcinoma by means of high-definition optical coherence tomography,” Exp. Dermatol. 25(9), 684–687 (2016).
[Crossref] [PubMed]

Boyer, J.

Bradish, J. R.

R. L. Konger, Z. Xu, R. P. Sahu, B. M. Rashid, S. R. Mehta, D. R. Mohamed, S. C. DaSilva-Arnold, J. R. Bradish, S. J. Warren, and Y. L. Kim, “Spatiotemporal assessments of dermal hyperemia enable accurate prediction of experimental cutaneous carcinogenesis as well as chemopreventive activity,” Cancer Res. 73(1), 150–159 (2013).
[Crossref] [PubMed]

Brandes, A.

N. Bodenschatz, A. Brandes, A. Liemert, and A. Kienle, “Sources of errors in spatial frequency domain imaging of scattering media,” J. Biomed. Opt. 19(7), 071405 (2014).
[Crossref] [PubMed]

Buckel, L. J.

S. T. Guenthner, R. M. Hurwitz, L. J. Buckel, and H. R. Gray, “Cutaneous squamous cell carcinomas consistently show histologic evidence of in situ changes: a clinicopathologic correlation,” J. Am. Acad. Dermatol. 41(3), 443–448 (1999).
[Crossref] [PubMed]

Burgess, S. A.

Chen, B. R.

Chen, C. W.

M. S. Ozturk, C. W. Chen, R. Ji, L. Zhao, B. N. Nguyen, J. P. Fisher, Y. Chen, and X. Intes, “Mesoscopic Fluorescence Molecular Tomography for Evaluating Engineered Tissues,” Ann. Biomed. Eng. 44(3), 667–679 (2016).
[Crossref] [PubMed]

Chen, Y.

M. S. Ozturk, C. W. Chen, R. Ji, L. Zhao, B. N. Nguyen, J. P. Fisher, Y. Chen, and X. Intes, “Mesoscopic Fluorescence Molecular Tomography for Evaluating Engineered Tissues,” Ann. Biomed. Eng. 44(3), 667–679 (2016).
[Crossref] [PubMed]

Cheng, J.

C. Kim, J. Cheng, and O. R. Colegio, “Cutaneous squamous cell carcinomas in solid organ transplant recipients: emerging strategies for surveillance, staging, and treatment,” Semin. Oncol. 43(3), 390–394 (2016).
[Crossref] [PubMed]

Coldiron, B. M.

H. W. Rogers, M. A. Weinstock, S. R. Feldman, and B. M. Coldiron, “Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the U.S. Population, 2012,” JAMA Dermatol. 151(10), 1081–1086 (2015).
[Crossref] [PubMed]

Colegio, O. R.

C. Kim, J. Cheng, and O. R. Colegio, “Cutaneous squamous cell carcinomas in solid organ transplant recipients: emerging strategies for surveillance, staging, and treatment,” Semin. Oncol. 43(3), 390–394 (2016).
[Crossref] [PubMed]

Connolly, S. M.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Correia, O.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Cuccia, D. J.

R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “A light emitting diode (LED) based spatial frequency domain imaging system for optimization of photodynamic therapy of nonmelanoma skin cancer: quantitative reflectance imaging,” Lasers Surg. Med. 45(4), 207–215 (2013).
[Crossref] [PubMed]

R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain,” J. Biomed. Opt. 16(12), 126013 (2011).
[Crossref] [PubMed]

D. J. Cuccia, F. Bevilacqua, A. J. Durkin, F. R. Ayers, and B. J. Tromberg, “Quantitation and mapping of tissue optical properties using modulated imaging,” J. Biomed. Opt. 14(2), 024012 (2009).
[Crossref] [PubMed]

D. J. Cuccia, F. Bevilacqua, A. J. Durkin, and B. J. Tromberg, “Modulated imaging: quantitative analysis and tomography of turbid media in the spatial-frequency domain,” Opt. Lett. 30(11), 1354–1356 (2005).
[Crossref] [PubMed]

Curiel-Lewandrowski, C. N.

N. E. McKenzie, K. Saboda, L. D. Duckett, R. Goldman, C. Hu, and C. N. Curiel-Lewandrowski, “Development of a photographic scale for consistency and guidance in dermatologic assessment of forearm sun damage,” Arch. Dermatol. 147(1), 31–36 (2011).
[Crossref] [PubMed]

DaSilva-Arnold, S. C.

R. L. Konger, Z. Xu, R. P. Sahu, B. M. Rashid, S. R. Mehta, D. R. Mohamed, S. C. DaSilva-Arnold, J. R. Bradish, S. J. Warren, and Y. L. Kim, “Spatiotemporal assessments of dermal hyperemia enable accurate prediction of experimental cutaneous carcinogenesis as well as chemopreventive activity,” Cancer Res. 73(1), 150–159 (2013).
[Crossref] [PubMed]

De Carvalho, N.

J. Olsen, L. Themstrup, N. De Carvalho, M. Mogensen, G. Pellacani, and G. B. Jemec, “Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma,” Photodiagn. Photodyn. Ther. 16, 44–49 (2016).
[Crossref] [PubMed]

Del Marmol, V.

A. Marneffe, M. Suppa, M. Miyamoto, V. Del Marmol, and M. Boone, “Validation of a diagnostic algorithm for the discrimination of actinic keratosis from normal skin and squamous cell carcinoma by means of high-definition optical coherence tomography,” Exp. Dermatol. 25(9), 684–687 (2016).
[Crossref] [PubMed]

Duckett, L. D.

N. E. McKenzie, K. Saboda, L. D. Duckett, R. Goldman, C. Hu, and C. N. Curiel-Lewandrowski, “Development of a photographic scale for consistency and guidance in dermatologic assessment of forearm sun damage,” Arch. Dermatol. 147(1), 31–36 (2011).
[Crossref] [PubMed]

Durkin, A. J.

R. B. Saager, A. Sharif, K. M. Kelly, and A. J. Durkin, “In vivo isolation of the effects of melanin from underlying hemodynamics across skin types using spatial frequency domain spectroscopy,” J. Biomed. Opt. 21(5), 057001 (2016).
[Crossref] [PubMed]

R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “A light emitting diode (LED) based spatial frequency domain imaging system for optimization of photodynamic therapy of nonmelanoma skin cancer: quantitative reflectance imaging,” Lasers Surg. Med. 45(4), 207–215 (2013).
[Crossref] [PubMed]

R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain,” J. Biomed. Opt. 16(12), 126013 (2011).
[Crossref] [PubMed]

D. J. Cuccia, F. Bevilacqua, A. J. Durkin, F. R. Ayers, and B. J. Tromberg, “Quantitation and mapping of tissue optical properties using modulated imaging,” J. Biomed. Opt. 14(2), 024012 (2009).
[Crossref] [PubMed]

D. J. Cuccia, F. Bevilacqua, A. J. Durkin, and B. J. Tromberg, “Modulated imaging: quantitative analysis and tomography of turbid media in the spatial-frequency domain,” Opt. Lett. 30(11), 1354–1356 (2005).
[Crossref] [PubMed]

Erdmann, R.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Feldman, S. R.

H. W. Rogers, M. A. Weinstock, S. R. Feldman, and B. M. Coldiron, “Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the U.S. Population, 2012,” JAMA Dermatol. 151(10), 1081–1086 (2015).
[Crossref] [PubMed]

Fisher, J. P.

M. S. Ozturk, C. W. Chen, R. Ji, L. Zhao, B. N. Nguyen, J. P. Fisher, Y. Chen, and X. Intes, “Mesoscopic Fluorescence Molecular Tomography for Evaluating Engineered Tissues,” Ann. Biomed. Eng. 44(3), 667–679 (2016).
[Crossref] [PubMed]

Foley, P.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Fuselier, T.

Gioux, S.

J. Angelo, C. R. Vargas, B. T. Lee, I. J. Bigio, and S. Gioux, “Ultrafast optical property map generation using lookup tables,” J. Biomed. Opt. 21(11), 110501 (2016).
[Crossref] [PubMed]

M. van de Giessen, J. P. Angelo, and S. Gioux, “Real-time, profile-corrected single snapshot imaging of optical properties,” Biomed. Opt. Express 6(10), 4051–4062 (2015).
[Crossref] [PubMed]

Goldman, R.

N. E. McKenzie, K. Saboda, L. D. Duckett, R. Goldman, C. Hu, and C. N. Curiel-Lewandrowski, “Development of a photographic scale for consistency and guidance in dermatologic assessment of forearm sun damage,” Arch. Dermatol. 147(1), 31–36 (2011).
[Crossref] [PubMed]

Gray, H. R.

S. T. Guenthner, R. M. Hurwitz, L. J. Buckel, and H. R. Gray, “Cutaneous squamous cell carcinomas consistently show histologic evidence of in situ changes: a clinicopathologic correlation,” J. Am. Acad. Dermatol. 41(3), 443–448 (1999).
[Crossref] [PubMed]

Guenthner, S. T.

S. T. Guenthner, R. M. Hurwitz, L. J. Buckel, and H. R. Gray, “Cutaneous squamous cell carcinomas consistently show histologic evidence of in situ changes: a clinicopathologic correlation,” J. Am. Acad. Dermatol. 41(3), 443–448 (1999).
[Crossref] [PubMed]

Gupta, A. K.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Halpern, A. C.

M. Rajadhyaksha, A. Marghoob, A. Rossi, A. C. Halpern, and K. S. Nehal, “Reflectance confocal microscopy of skin in vivo: From bench to bedside,” Lasers Surg. Med. 49(1), 7–19 (2017).
[Crossref] [PubMed]

Henderson, B. W.

Hillman, E. M.

Hu, C.

N. E. McKenzie, K. Saboda, L. D. Duckett, R. Goldman, C. Hu, and C. N. Curiel-Lewandrowski, “Development of a photographic scale for consistency and guidance in dermatologic assessment of forearm sun damage,” Arch. Dermatol. 147(1), 31–36 (2011).
[Crossref] [PubMed]

Huihui, J.

D. J. Rohrbach, D. Muffoletto, J. Huihui, R. Saager, K. Keymel, A. Paquette, J. Morgan, N. Zeitouni, and U. Sunar, “Preoperative mapping of nonmelanoma skin cancer using spatial frequency domain and ultrasound imaging,” Acad. Radiol. 21(2), 263–270 (2014).
[Crossref] [PubMed]

Hurwitz, R. M.

S. T. Guenthner, R. M. Hurwitz, L. J. Buckel, and H. R. Gray, “Cutaneous squamous cell carcinomas consistently show histologic evidence of in situ changes: a clinicopathologic correlation,” J. Am. Acad. Dermatol. 41(3), 443–448 (1999).
[Crossref] [PubMed]

Intes, X.

M. S. Ozturk, C. W. Chen, R. Ji, L. Zhao, B. N. Nguyen, J. P. Fisher, Y. Chen, and X. Intes, “Mesoscopic Fluorescence Molecular Tomography for Evaluating Engineered Tissues,” Ann. Biomed. Eng. 44(3), 667–679 (2016).
[Crossref] [PubMed]

M. S. Ozturk, D. Rohrbach, U. Sunar, and X. Intes, “Mesoscopic fluorescence tomography of a photosensitizer (HPPH) 3D biodistribution in skin cancer,” Acad. Radiol. 21(2), 271–280 (2014).
[Crossref] [PubMed]

Jacobs, A.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Jemec, G. B.

J. Olsen, L. Themstrup, N. De Carvalho, M. Mogensen, G. Pellacani, and G. B. Jemec, “Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma,” Photodiagn. Photodyn. Ther. 16, 44–49 (2016).
[Crossref] [PubMed]

Ji, R.

M. S. Ozturk, C. W. Chen, R. Ji, L. Zhao, B. N. Nguyen, J. P. Fisher, Y. Chen, and X. Intes, “Mesoscopic Fluorescence Molecular Tomography for Evaluating Engineered Tissues,” Ann. Biomed. Eng. 44(3), 667–679 (2016).
[Crossref] [PubMed]

Johnson, T. M.

Kelly, K. M.

R. B. Saager, A. Sharif, K. M. Kelly, and A. J. Durkin, “In vivo isolation of the effects of melanin from underlying hemodynamics across skin types using spatial frequency domain spectroscopy,” J. Biomed. Opt. 21(5), 057001 (2016).
[Crossref] [PubMed]

R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “A light emitting diode (LED) based spatial frequency domain imaging system for optimization of photodynamic therapy of nonmelanoma skin cancer: quantitative reflectance imaging,” Lasers Surg. Med. 45(4), 207–215 (2013).
[Crossref] [PubMed]

R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain,” J. Biomed. Opt. 16(12), 126013 (2011).
[Crossref] [PubMed]

Kerl, H.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Keymel, K.

D. J. Rohrbach, D. Muffoletto, J. Huihui, R. Saager, K. Keymel, A. Paquette, J. Morgan, N. Zeitouni, and U. Sunar, “Preoperative mapping of nonmelanoma skin cancer using spatial frequency domain and ultrasound imaging,” Acad. Radiol. 21(2), 263–270 (2014).
[Crossref] [PubMed]

Kienle, A.

N. Bodenschatz, A. Brandes, A. Liemert, and A. Kienle, “Sources of errors in spatial frequency domain imaging of scattering media,” J. Biomed. Opt. 19(7), 071405 (2014).
[Crossref] [PubMed]

Kim, C.

C. Kim, J. Cheng, and O. R. Colegio, “Cutaneous squamous cell carcinomas in solid organ transplant recipients: emerging strategies for surveillance, staging, and treatment,” Semin. Oncol. 43(3), 390–394 (2016).
[Crossref] [PubMed]

Kim, Y. L.

R. L. Konger, Z. Xu, R. P. Sahu, B. M. Rashid, S. R. Mehta, D. R. Mohamed, S. C. DaSilva-Arnold, J. R. Bradish, S. J. Warren, and Y. L. Kim, “Spatiotemporal assessments of dermal hyperemia enable accurate prediction of experimental cutaneous carcinogenesis as well as chemopreventive activity,” Cancer Res. 73(1), 150–159 (2013).
[Crossref] [PubMed]

Konger, R. L.

R. L. Konger, Z. Xu, R. P. Sahu, B. M. Rashid, S. R. Mehta, D. R. Mohamed, S. C. DaSilva-Arnold, J. R. Bradish, S. J. Warren, and Y. L. Kim, “Spatiotemporal assessments of dermal hyperemia enable accurate prediction of experimental cutaneous carcinogenesis as well as chemopreventive activity,” Cancer Res. 73(1), 150–159 (2013).
[Crossref] [PubMed]

Lee, B. T.

J. Angelo, C. R. Vargas, B. T. Lee, I. J. Bigio, and S. Gioux, “Ultrafast optical property map generation using lookup tables,” J. Biomed. Opt. 21(11), 110501 (2016).
[Crossref] [PubMed]

Liemert, A.

N. Bodenschatz, A. Brandes, A. Liemert, and A. Kienle, “Sources of errors in spatial frequency domain imaging of scattering media,” J. Biomed. Opt. 19(7), 071405 (2014).
[Crossref] [PubMed]

Lim, H. W.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Marghoob, A.

M. Rajadhyaksha, A. Marghoob, A. Rossi, A. C. Halpern, and K. S. Nehal, “Reflectance confocal microscopy of skin in vivo: From bench to bedside,” Lasers Surg. Med. 49(1), 7–19 (2017).
[Crossref] [PubMed]

Marneffe, A.

A. Marneffe, M. Suppa, M. Miyamoto, V. Del Marmol, and M. Boone, “Validation of a diagnostic algorithm for the discrimination of actinic keratosis from normal skin and squamous cell carcinoma by means of high-definition optical coherence tomography,” Exp. Dermatol. 25(9), 684–687 (2016).
[Crossref] [PubMed]

Martin, G.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

McKenzie, N. E.

N. E. McKenzie, K. Saboda, L. D. Duckett, R. Goldman, C. Hu, and C. N. Curiel-Lewandrowski, “Development of a photographic scale for consistency and guidance in dermatologic assessment of forearm sun damage,” Arch. Dermatol. 147(1), 31–36 (2011).
[Crossref] [PubMed]

Mehta, S. R.

R. L. Konger, Z. Xu, R. P. Sahu, B. M. Rashid, S. R. Mehta, D. R. Mohamed, S. C. DaSilva-Arnold, J. R. Bradish, S. J. Warren, and Y. L. Kim, “Spatiotemporal assessments of dermal hyperemia enable accurate prediction of experimental cutaneous carcinogenesis as well as chemopreventive activity,” Cancer Res. 73(1), 150–159 (2013).
[Crossref] [PubMed]

Miyamoto, M.

A. Marneffe, M. Suppa, M. Miyamoto, V. Del Marmol, and M. Boone, “Validation of a diagnostic algorithm for the discrimination of actinic keratosis from normal skin and squamous cell carcinoma by means of high-definition optical coherence tomography,” Exp. Dermatol. 25(9), 684–687 (2016).
[Crossref] [PubMed]

Mogensen, M.

J. Olsen, L. Themstrup, N. De Carvalho, M. Mogensen, G. Pellacani, and G. B. Jemec, “Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma,” Photodiagn. Photodyn. Ther. 16, 44–49 (2016).
[Crossref] [PubMed]

Mohamed, D. R.

R. L. Konger, Z. Xu, R. P. Sahu, B. M. Rashid, S. R. Mehta, D. R. Mohamed, S. C. DaSilva-Arnold, J. R. Bradish, S. J. Warren, and Y. L. Kim, “Spatiotemporal assessments of dermal hyperemia enable accurate prediction of experimental cutaneous carcinogenesis as well as chemopreventive activity,” Cancer Res. 73(1), 150–159 (2013).
[Crossref] [PubMed]

Morgan, J.

D. J. Rohrbach, D. Muffoletto, J. Huihui, R. Saager, K. Keymel, A. Paquette, J. Morgan, N. Zeitouni, and U. Sunar, “Preoperative mapping of nonmelanoma skin cancer using spatial frequency domain and ultrasound imaging,” Acad. Radiol. 21(2), 263–270 (2014).
[Crossref] [PubMed]

U. Sunar, D. J. Rohrbach, J. Morgan, N. Zeitouni, and B. W. Henderson, “Quantification of PpIX concentration in basal cell carcinoma and squamous cell carcinoma models using spatial frequency domain imaging,” Biomed. Opt. Express 4(4), 531–537 (2013).
[Crossref] [PubMed]

Mourant, J. R.

Muffoletto, D.

D. J. Rohrbach, N. C. Zeitouni, D. Muffoletto, R. Saager, B. J. Tromberg, and U. Sunar, “Characterization of nonmelanoma skin cancer for light therapy using spatial frequency domain imaging,” Biomed. Opt. Express 6(5), 1761–1766 (2015).
[Crossref] [PubMed]

D. J. Rohrbach, D. Muffoletto, J. Huihui, R. Saager, K. Keymel, A. Paquette, J. Morgan, N. Zeitouni, and U. Sunar, “Preoperative mapping of nonmelanoma skin cancer using spatial frequency domain and ultrasound imaging,” Acad. Radiol. 21(2), 263–270 (2014).
[Crossref] [PubMed]

Muldoon, T. J.

Nast, A.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Nehal, K. S.

M. Rajadhyaksha, A. Marghoob, A. Rossi, A. C. Halpern, and K. S. Nehal, “Reflectance confocal microscopy of skin in vivo: From bench to bedside,” Lasers Surg. Med. 49(1), 7–19 (2017).
[Crossref] [PubMed]

Nguyen, B. N.

M. S. Ozturk, C. W. Chen, R. Ji, L. Zhao, B. N. Nguyen, J. P. Fisher, Y. Chen, and X. Intes, “Mesoscopic Fluorescence Molecular Tomography for Evaluating Engineered Tissues,” Ann. Biomed. Eng. 44(3), 667–679 (2016).
[Crossref] [PubMed]

Olsen, J.

J. Olsen, L. Themstrup, N. De Carvalho, M. Mogensen, G. Pellacani, and G. B. Jemec, “Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma,” Photodiagn. Photodyn. Ther. 16, 44–49 (2016).
[Crossref] [PubMed]

Ozturk, M. S.

M. S. Ozturk, C. W. Chen, R. Ji, L. Zhao, B. N. Nguyen, J. P. Fisher, Y. Chen, and X. Intes, “Mesoscopic Fluorescence Molecular Tomography for Evaluating Engineered Tissues,” Ann. Biomed. Eng. 44(3), 667–679 (2016).
[Crossref] [PubMed]

M. S. Ozturk, D. Rohrbach, U. Sunar, and X. Intes, “Mesoscopic fluorescence tomography of a photosensitizer (HPPH) 3D biodistribution in skin cancer,” Acad. Radiol. 21(2), 271–280 (2014).
[Crossref] [PubMed]

Paquet, M.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Paquette, A.

D. J. Rohrbach, D. Muffoletto, J. Huihui, R. Saager, K. Keymel, A. Paquette, J. Morgan, N. Zeitouni, and U. Sunar, “Preoperative mapping of nonmelanoma skin cancer using spatial frequency domain and ultrasound imaging,” Acad. Radiol. 21(2), 263–270 (2014).
[Crossref] [PubMed]

Pariser, D. M.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Pellacani, G.

J. Olsen, L. Themstrup, N. De Carvalho, M. Mogensen, G. Pellacani, and G. B. Jemec, “Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma,” Photodiagn. Photodyn. Ther. 16, 44–49 (2016).
[Crossref] [PubMed]

Rajadhyaksha, M.

M. Rajadhyaksha, A. Marghoob, A. Rossi, A. C. Halpern, and K. S. Nehal, “Reflectance confocal microscopy of skin in vivo: From bench to bedside,” Lasers Surg. Med. 49(1), 7–19 (2017).
[Crossref] [PubMed]

Rashid, B. M.

R. L. Konger, Z. Xu, R. P. Sahu, B. M. Rashid, S. R. Mehta, D. R. Mohamed, S. C. DaSilva-Arnold, J. R. Bradish, S. J. Warren, and Y. L. Kim, “Spatiotemporal assessments of dermal hyperemia enable accurate prediction of experimental cutaneous carcinogenesis as well as chemopreventive activity,” Cancer Res. 73(1), 150–159 (2013).
[Crossref] [PubMed]

Ratner, D.

Rogers, H. W.

H. W. Rogers, M. A. Weinstock, S. R. Feldman, and B. M. Coldiron, “Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the U.S. Population, 2012,” JAMA Dermatol. 151(10), 1081–1086 (2015).
[Crossref] [PubMed]

Rohrbach, D.

M. S. Ozturk, D. Rohrbach, U. Sunar, and X. Intes, “Mesoscopic fluorescence tomography of a photosensitizer (HPPH) 3D biodistribution in skin cancer,” Acad. Radiol. 21(2), 271–280 (2014).
[Crossref] [PubMed]

Rohrbach, D. J.

Rossi, A.

M. Rajadhyaksha, A. Marghoob, A. Rossi, A. C. Halpern, and K. S. Nehal, “Reflectance confocal microscopy of skin in vivo: From bench to bedside,” Lasers Surg. Med. 49(1), 7–19 (2017).
[Crossref] [PubMed]

Rosumeck, S.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Röwert-Huber, H. J.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Saager, R.

D. J. Rohrbach, N. C. Zeitouni, D. Muffoletto, R. Saager, B. J. Tromberg, and U. Sunar, “Characterization of nonmelanoma skin cancer for light therapy using spatial frequency domain imaging,” Biomed. Opt. Express 6(5), 1761–1766 (2015).
[Crossref] [PubMed]

D. J. Rohrbach, D. Muffoletto, J. Huihui, R. Saager, K. Keymel, A. Paquette, J. Morgan, N. Zeitouni, and U. Sunar, “Preoperative mapping of nonmelanoma skin cancer using spatial frequency domain and ultrasound imaging,” Acad. Radiol. 21(2), 263–270 (2014).
[Crossref] [PubMed]

Saager, R. B.

R. B. Saager, A. Sharif, K. M. Kelly, and A. J. Durkin, “In vivo isolation of the effects of melanin from underlying hemodynamics across skin types using spatial frequency domain spectroscopy,” J. Biomed. Opt. 21(5), 057001 (2016).
[Crossref] [PubMed]

R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “A light emitting diode (LED) based spatial frequency domain imaging system for optimization of photodynamic therapy of nonmelanoma skin cancer: quantitative reflectance imaging,” Lasers Surg. Med. 45(4), 207–215 (2013).
[Crossref] [PubMed]

R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain,” J. Biomed. Opt. 16(12), 126013 (2011).
[Crossref] [PubMed]

Saboda, K.

N. E. McKenzie, K. Saboda, L. D. Duckett, R. Goldman, C. Hu, and C. N. Curiel-Lewandrowski, “Development of a photographic scale for consistency and guidance in dermatologic assessment of forearm sun damage,” Arch. Dermatol. 147(1), 31–36 (2011).
[Crossref] [PubMed]

Saggese, S.

R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “A light emitting diode (LED) based spatial frequency domain imaging system for optimization of photodynamic therapy of nonmelanoma skin cancer: quantitative reflectance imaging,” Lasers Surg. Med. 45(4), 207–215 (2013).
[Crossref] [PubMed]

R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain,” J. Biomed. Opt. 16(12), 126013 (2011).
[Crossref] [PubMed]

Sahota, A.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Sahu, R. P.

R. L. Konger, Z. Xu, R. P. Sahu, B. M. Rashid, S. R. Mehta, D. R. Mohamed, S. C. DaSilva-Arnold, J. R. Bradish, S. J. Warren, and Y. L. Kim, “Spatiotemporal assessments of dermal hyperemia enable accurate prediction of experimental cutaneous carcinogenesis as well as chemopreventive activity,” Cancer Res. 73(1), 150–159 (2013).
[Crossref] [PubMed]

Sangueza, O. P.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Sharif, A.

R. B. Saager, A. Sharif, K. M. Kelly, and A. J. Durkin, “In vivo isolation of the effects of melanin from underlying hemodynamics across skin types using spatial frequency domain spectroscopy,” J. Biomed. Opt. 21(5), 057001 (2016).
[Crossref] [PubMed]

Shumack, S.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Sporbeck, B.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Stockfleth, E.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Sunar, U.

D. J. Rohrbach, N. C. Zeitouni, D. Muffoletto, R. Saager, B. J. Tromberg, and U. Sunar, “Characterization of nonmelanoma skin cancer for light therapy using spatial frequency domain imaging,” Biomed. Opt. Express 6(5), 1761–1766 (2015).
[Crossref] [PubMed]

D. J. Rohrbach, D. Muffoletto, J. Huihui, R. Saager, K. Keymel, A. Paquette, J. Morgan, N. Zeitouni, and U. Sunar, “Preoperative mapping of nonmelanoma skin cancer using spatial frequency domain and ultrasound imaging,” Acad. Radiol. 21(2), 263–270 (2014).
[Crossref] [PubMed]

M. S. Ozturk, D. Rohrbach, U. Sunar, and X. Intes, “Mesoscopic fluorescence tomography of a photosensitizer (HPPH) 3D biodistribution in skin cancer,” Acad. Radiol. 21(2), 271–280 (2014).
[Crossref] [PubMed]

U. Sunar, D. J. Rohrbach, J. Morgan, N. Zeitouni, and B. W. Henderson, “Quantification of PpIX concentration in basal cell carcinoma and squamous cell carcinoma models using spatial frequency domain imaging,” Biomed. Opt. Express 4(4), 531–537 (2013).
[Crossref] [PubMed]

Suppa, M.

A. Marneffe, M. Suppa, M. Miyamoto, V. Del Marmol, and M. Boone, “Validation of a diagnostic algorithm for the discrimination of actinic keratosis from normal skin and squamous cell carcinoma by means of high-definition optical coherence tomography,” Exp. Dermatol. 25(9), 684–687 (2016).
[Crossref] [PubMed]

Swanson, N. A.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Themstrup, L.

J. Olsen, L. Themstrup, N. De Carvalho, M. Mogensen, G. Pellacani, and G. B. Jemec, “Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma,” Photodiagn. Photodyn. Ther. 16, 44–49 (2016).
[Crossref] [PubMed]

Torezan, L.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Tromberg, B. J.

van de Giessen, M.

Vargas, C. R.

J. Angelo, C. R. Vargas, B. T. Lee, I. J. Bigio, and S. Gioux, “Ultrafast optical property map generation using lookup tables,” J. Biomed. Opt. 21(11), 110501 (2016).
[Crossref] [PubMed]

Warren, S. J.

R. L. Konger, Z. Xu, R. P. Sahu, B. M. Rashid, S. R. Mehta, D. R. Mohamed, S. C. DaSilva-Arnold, J. R. Bradish, S. J. Warren, and Y. L. Kim, “Spatiotemporal assessments of dermal hyperemia enable accurate prediction of experimental cutaneous carcinogenesis as well as chemopreventive activity,” Cancer Res. 73(1), 150–159 (2013).
[Crossref] [PubMed]

Weinstock, M. A.

H. W. Rogers, M. A. Weinstock, S. R. Feldman, and B. M. Coldiron, “Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the U.S. Population, 2012,” JAMA Dermatol. 151(10), 1081–1086 (2015).
[Crossref] [PubMed]

Werner, R. N.

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

Xu, Z.

R. L. Konger, Z. Xu, R. P. Sahu, B. M. Rashid, S. R. Mehta, D. R. Mohamed, S. C. DaSilva-Arnold, J. R. Bradish, S. J. Warren, and Y. L. Kim, “Spatiotemporal assessments of dermal hyperemia enable accurate prediction of experimental cutaneous carcinogenesis as well as chemopreventive activity,” Cancer Res. 73(1), 150–159 (2013).
[Crossref] [PubMed]

Zeitouni, N.

D. J. Rohrbach, D. Muffoletto, J. Huihui, R. Saager, K. Keymel, A. Paquette, J. Morgan, N. Zeitouni, and U. Sunar, “Preoperative mapping of nonmelanoma skin cancer using spatial frequency domain and ultrasound imaging,” Acad. Radiol. 21(2), 263–270 (2014).
[Crossref] [PubMed]

U. Sunar, D. J. Rohrbach, J. Morgan, N. Zeitouni, and B. W. Henderson, “Quantification of PpIX concentration in basal cell carcinoma and squamous cell carcinoma models using spatial frequency domain imaging,” Biomed. Opt. Express 4(4), 531–537 (2013).
[Crossref] [PubMed]

Zeitouni, N. C.

Zhao, L.

M. S. Ozturk, C. W. Chen, R. Ji, L. Zhao, B. N. Nguyen, J. P. Fisher, Y. Chen, and X. Intes, “Mesoscopic Fluorescence Molecular Tomography for Evaluating Engineered Tissues,” Ann. Biomed. Eng. 44(3), 667–679 (2016).
[Crossref] [PubMed]

Acad. Radiol. (2)

M. S. Ozturk, D. Rohrbach, U. Sunar, and X. Intes, “Mesoscopic fluorescence tomography of a photosensitizer (HPPH) 3D biodistribution in skin cancer,” Acad. Radiol. 21(2), 271–280 (2014).
[Crossref] [PubMed]

D. J. Rohrbach, D. Muffoletto, J. Huihui, R. Saager, K. Keymel, A. Paquette, J. Morgan, N. Zeitouni, and U. Sunar, “Preoperative mapping of nonmelanoma skin cancer using spatial frequency domain and ultrasound imaging,” Acad. Radiol. 21(2), 263–270 (2014).
[Crossref] [PubMed]

Ann. Biomed. Eng. (1)

M. S. Ozturk, C. W. Chen, R. Ji, L. Zhao, B. N. Nguyen, J. P. Fisher, Y. Chen, and X. Intes, “Mesoscopic Fluorescence Molecular Tomography for Evaluating Engineered Tissues,” Ann. Biomed. Eng. 44(3), 667–679 (2016).
[Crossref] [PubMed]

Appl. Opt. (1)

Arch. Dermatol. (1)

N. E. McKenzie, K. Saboda, L. D. Duckett, R. Goldman, C. Hu, and C. N. Curiel-Lewandrowski, “Development of a photographic scale for consistency and guidance in dermatologic assessment of forearm sun damage,” Arch. Dermatol. 147(1), 31–36 (2011).
[Crossref] [PubMed]

Biomed. Opt. Express (4)

Cancer Res. (1)

R. L. Konger, Z. Xu, R. P. Sahu, B. M. Rashid, S. R. Mehta, D. R. Mohamed, S. C. DaSilva-Arnold, J. R. Bradish, S. J. Warren, and Y. L. Kim, “Spatiotemporal assessments of dermal hyperemia enable accurate prediction of experimental cutaneous carcinogenesis as well as chemopreventive activity,” Cancer Res. 73(1), 150–159 (2013).
[Crossref] [PubMed]

Exp. Dermatol. (1)

A. Marneffe, M. Suppa, M. Miyamoto, V. Del Marmol, and M. Boone, “Validation of a diagnostic algorithm for the discrimination of actinic keratosis from normal skin and squamous cell carcinoma by means of high-definition optical coherence tomography,” Exp. Dermatol. 25(9), 684–687 (2016).
[Crossref] [PubMed]

J. Am. Acad. Dermatol. (1)

S. T. Guenthner, R. M. Hurwitz, L. J. Buckel, and H. R. Gray, “Cutaneous squamous cell carcinomas consistently show histologic evidence of in situ changes: a clinicopathologic correlation,” J. Am. Acad. Dermatol. 41(3), 443–448 (1999).
[Crossref] [PubMed]

J. Biomed. Opt. (5)

D. J. Cuccia, F. Bevilacqua, A. J. Durkin, F. R. Ayers, and B. J. Tromberg, “Quantitation and mapping of tissue optical properties using modulated imaging,” J. Biomed. Opt. 14(2), 024012 (2009).
[Crossref] [PubMed]

J. Angelo, C. R. Vargas, B. T. Lee, I. J. Bigio, and S. Gioux, “Ultrafast optical property map generation using lookup tables,” J. Biomed. Opt. 21(11), 110501 (2016).
[Crossref] [PubMed]

R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain,” J. Biomed. Opt. 16(12), 126013 (2011).
[Crossref] [PubMed]

N. Bodenschatz, A. Brandes, A. Liemert, and A. Kienle, “Sources of errors in spatial frequency domain imaging of scattering media,” J. Biomed. Opt. 19(7), 071405 (2014).
[Crossref] [PubMed]

R. B. Saager, A. Sharif, K. M. Kelly, and A. J. Durkin, “In vivo isolation of the effects of melanin from underlying hemodynamics across skin types using spatial frequency domain spectroscopy,” J. Biomed. Opt. 21(5), 057001 (2016).
[Crossref] [PubMed]

J. Eur. Acad. Dermatol. Venereol. (1)

R. N. Werner, E. Stockfleth, S. M. Connolly, O. Correia, R. Erdmann, P. Foley, A. K. Gupta, A. Jacobs, H. Kerl, H. W. Lim, G. Martin, M. Paquet, D. M. Pariser, S. Rosumeck, H. J. Röwert-Huber, A. Sahota, O. P. Sangueza, S. Shumack, B. Sporbeck, N. A. Swanson, L. Torezan, A. Nast, International League of Dermatological SocietiesEuropean Dermatology Forum, “Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - International League of Dermatological Societies in cooperation with the European Dermatology Forum - Short version,” J. Eur. Acad. Dermatol. Venereol. 29(11), 2069–2079 (2015).
[Crossref] [PubMed]

JAMA Dermatol. (1)

H. W. Rogers, M. A. Weinstock, S. R. Feldman, and B. M. Coldiron, “Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the U.S. Population, 2012,” JAMA Dermatol. 151(10), 1081–1086 (2015).
[Crossref] [PubMed]

Lasers Surg. Med. (2)

M. Rajadhyaksha, A. Marghoob, A. Rossi, A. C. Halpern, and K. S. Nehal, “Reflectance confocal microscopy of skin in vivo: From bench to bedside,” Lasers Surg. Med. 49(1), 7–19 (2017).
[Crossref] [PubMed]

R. B. Saager, D. J. Cuccia, S. Saggese, K. M. Kelly, and A. J. Durkin, “A light emitting diode (LED) based spatial frequency domain imaging system for optimization of photodynamic therapy of nonmelanoma skin cancer: quantitative reflectance imaging,” Lasers Surg. Med. 45(4), 207–215 (2013).
[Crossref] [PubMed]

Opt. Lett. (1)

Photodiagn. Photodyn. Ther. (1)

J. Olsen, L. Themstrup, N. De Carvalho, M. Mogensen, G. Pellacani, and G. B. Jemec, “Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma,” Photodiagn. Photodyn. Ther. 16, 44–49 (2016).
[Crossref] [PubMed]

Semin. Oncol. (1)

C. Kim, J. Cheng, and O. R. Colegio, “Cutaneous squamous cell carcinomas in solid organ transplant recipients: emerging strategies for surveillance, staging, and treatment,” Semin. Oncol. 43(3), 390–394 (2016).
[Crossref] [PubMed]

Cited By

OSA participates in Crossref's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (7)

Fig. 1
Fig. 1 Clinical pictures of three subjects (P1-3) with increasing levels of photodamage examined by SFDI with the approximate location of the imaged area bounded by the red rectangles.
Fig. 2
Fig. 2 (a) Schematic diagram and (b) photo of SFDI instrument for imaging lesions on arm.
Fig. 3
Fig. 3 Reflectance (Rd) images of all three patients at 590nm. Red arrows for patient 3 highlights the visible actinic lesion.
Fig. 4
Fig. 4 (a), (b), (c) Absorption imaging maps for all three patients at 590nm. Red arrows highlight the visible lesion for patient 3. (d) Histograms of the absorption parameter for the three patients at 590 nm.
Fig. 5
Fig. 5 Physiological parameter quantified from absorption maps. (a) shows the spatial maps for each parameter for each patient. Arrows highlight the visible lesion for patient 3. (b) shows the summary histogram of each parameter.
Fig. 6
Fig. 6 (a), (b), (c) Scattering imaging maps for all three patients at 590nm. Red arrows highlight the visible lesion for patient 3. (d) Histograms of the scattering parameter for the three patients at 590 nm.
Fig. 7
Fig. 7 Scattering amplitude, A, and power, b, maps. (a) shows the spatial maps for each parameter for each patient. Red arrows highlight the visible lesion for patient 3. (b) shows the summary histogram of each parameter.

Metrics