Abstract

Indocyanine green (ICG) is a near-infrared fluorophore approved for human use which has been widely used for various clinical applications. Despite the well-established clinical usage, our understanding about the microscopic in vivo pharmacokinetics of systemically administered ICG has been relatively limited. In this work, we successfully visualized real-time in vivo pharmacokinetic dynamics of the intravenously injected free-form and liposomal ICG in cellular resolution by utilizing a custom-built video-rate near infrared laser-scanning confocal microscopy system. Initial perfusion and clearance from blood stream, diffusion into perisinusoidal space, and subsequent absorption into hepatocyte were directly visualized in vivo. The quantification analysis utilizing the real-time image sequences revealed distinct dynamic in vivo pharmacokinetic behavior of free-form and liposomal ICG.

© 2017 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Noninvasive depth estimation using tissue optical properties and a dual-wavelength fluorescent molecular probe in vivo

Jessica P. Miller, Dolonchampa Maji, Jesse Lam, Bruce J. Tromberg, and Samuel Achilefu
Biomed. Opt. Express 8(6) 3095-3109 (2017)

Vascular patterning of subcutaneous mouse fibrosarcomas expressing individual VEGF isoforms can be differentiated using angiographic optical coherence tomography

Robert A. Byers, Matthew Fisher, Nicola J. Brown, Gillian M. Tozer, and Stephen J. Matcher
Biomed. Opt. Express 8(10) 4551-4567 (2017)

Optical imaging for the assessment of hepatocyte metabolic state in ischemia and reperfusion injuries

Mette F. la Cour, Shima Mehrvar, Joohyun Kim, Alicia Martin, Michael A. Zimmerman, Johnny C. Hong, and Mahsa Ranji
Biomed. Opt. Express 8(10) 4419-4426 (2017)

References

  • View by:
  • |
  • |
  • |

  1. T. Iijima, T. Aoyagi, Y. Iwao, J. Masuda, M. Fuse, N. Kobayashi, and H. Sankawa, “Cardiac output and circulating blood volume analysis by pulse dye-densitometry,” J. Clin. Monit. 13(2), 81–89 (1997).
    [Crossref] [PubMed]
  2. O. Okochi, T. Kaneko, H. Sugimoto, S. Inoue, S. Takeda, and A. Nakao, “ICG pulse spectrophotometry for perioperative liver function in hepatectomy,” J. Surg. Res. 103(1), 109–113 (2002).
    [Crossref] [PubMed]
  3. T. Desmettre, J. M. Devoisselle, and S. Mordon, “Fluorescence properties and metabolic features of indocyanine green (ICG) as related to angiography,” Surv. Ophthalmol. 45(1), 15–27 (2000).
    [Crossref] [PubMed]
  4. A. M. Smith, M. C. Mancini, and S. Nie, “Bioimaging: Second window for in vivo imaging,” Nat. Nanotechnol. 4(11), 710–711 (2009).
    [Crossref] [PubMed]
  5. R. Weissleder, “A clearer vision for in vivo imaging,” Nat. Biotechnol. 19(4), 316–317 (2001).
    [Crossref] [PubMed]
  6. J. V. Frangioni, “In vivo near-infrared fluorescence imaging,” Curr. Opin. Chem. Biol. 7(5), 626–634 (2003).
    [Crossref] [PubMed]
  7. V. Ntziachristos, C. Bremer, and R. Weissleder, “Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging,” Eur. Radiol. 13(1), 195–208 (2003).
    [PubMed]
  8. B. E. Schaafsma, J. S. D. Mieog, M. Hutteman, J. R. van der Vorst, P. J. K. Kuppen, C. W. G. M. Löwik, J. V. Frangioni, C. J. H. van de Velde, and A. L. Vahrmeijer, “The Clinical Use of Indocyanine Green as a near-Infrared Fluorescent Contrast Agent for Image-Guided Oncologic Surgery,” J. Surg. Oncol. 104(3), 323–332 (2011).
    [Crossref] [PubMed]
  9. S. Kwon, G. D. Agollah, G. Wu, W. Chan, and E. M. Sevick-Muraca, “Direct visualization of changes of lymphatic function and drainage pathways in lymph node metastasis of B16F10 melanoma using near-infrared fluorescence imaging,” Biomed. Opt. Express 4(6), 967–977 (2013).
    [Crossref] [PubMed]
  10. R. Sharma, W. Wang, J. C. Rasmussen, A. Joshi, J. P. Houston, K. E. Adams, A. Cameron, S. Ke, S. Kwon, M. E. Mawad, and E. M. Sevick-Muraca, “Quantitative imaging of lymph function,” Am. J. Physiol. Heart Circ. Physiol. 292(6), H3109–H3118 (2007).
    [Crossref] [PubMed]
  11. N. Unno, M. Nishiyama, M. Suzuki, N. Yamamoto, K. Inuzuka, D. Sagara, H. Tanaka, and H. Konno, “Quantitative lymph imaging for assessment of lymph function using indocyanine green fluorescence lymphography,” Eur. J. Vasc. Endovasc. Surg. 36(2), 230–236 (2008).
    [Crossref] [PubMed]
  12. C. Holm, M. Mayr, E. Höfter, A. Becker, U. J. Pfeiffer, and W. Mühlbauer, “Intraoperative evaluation of skin-flap viability using laser-induced fluorescence of indocyanine green,” Br. J. Plast. Surg. 55(8), 635–644 (2002).
    [Crossref] [PubMed]
  13. C. Habermehl, C. H. Schmitz, and J. Steinbrink, “Contrast enhanced high-resolution diffuse optical tomography of the human brain using ICG,” Opt. Express 19(19), 18636–18644 (2011).
    [Crossref] [PubMed]
  14. T. Holmes, A. Invernizzi, S. Larkin, and G. Staurenghi, “Dynamic indocyanine green angiography measurements,” J. Biomed. Opt. 17(11), 116028 (2012).
    [Crossref] [PubMed]
  15. M. Choi, K. Choi, S. W. Ryu, J. Lee, and C. Choi, “Dynamic fluorescence imaging for multiparametric measurement of tumor vasculature,” J. Biomed. Opt. 16(4), 046008 (2011).
    [Crossref] [PubMed]
  16. Y. Kang, M. Choi, J. Lee, G. Y. Koh, K. Kwon, and C. Choi, “Quantitative Analysis of Peripheral Tissue Perfusion Using Spatiotemporal Molecular Dynamics,” PLoS One 4(1), e4275 (2009).
    [Crossref] [PubMed]
  17. N. L. Martirosyan, D. D. Cavalcanti, J. M. Eschbacher, P. M. Delaney, A. C. Scheck, M. G. Abdelwahab, P. Nakaji, R. F. Spetzler, and M. C. Preul, “Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor Laboratory investigation,” J. Neurosurg. 115(6), 1131–1138 (2011).
    [Crossref] [PubMed]
  18. W. Piyawattanametha, H. Ra, Z. Qiu, S. Friedland, J. T. C. Liu, K. Loewke, G. S. Kino, O. Solgaard, T. D. Wang, M. J. Mandella, and C. H. Contag, “In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract,” J. Biomed. Opt. 17(2), 021102 (2012).
    [Crossref] [PubMed]
  19. H. Skvara, H. Kittler, J. A. Schmid, U. Plut, and C. Jonak, “In vivo fluorescence confocal microscopy: indocyanine green enhances the contrast of epidermal and dermal structures,” J. Biomed. Opt. 16(9), 096010 (2011).
    [Crossref] [PubMed]
  20. S. T. Proulx, P. Luciani, S. Derzsi, M. Rinderknecht, V. Mumprecht, J. C. Leroux, and M. Detmar, “Quantitative Imaging of Lymphatic Function with Liposomal Indocyanine Green,” Cancer Res. 70(18), 7053–7062 (2010).
    [Crossref] [PubMed]
  21. A. Gabizon and D. Papahadjopoulos, “Liposome Formulations with Prolonged Circulation Time in Blood and Enhanced Uptake by Tumors,” Proc. Natl. Acad. Sci. U.S.A. 85(18), 6949–6953 (1988).
    [Crossref] [PubMed]
  22. W. T. Song, Z. H. Tang, D. W. Zhang, N. Burton, W. Driessen, and X. S. Chen, “Comprehensive studies of pharmacokinetics and biodistribution of indocyanine green and liposomal indocyanine green by multispectral optoacoustic tomography,” Rsc Adv 5(5), 3807–3813 (2015).
    [Crossref]
  23. C. Zheng, M. Zheng, P. Gong, D. Jia, P. Zhang, B. Shi, Z. Sheng, Y. Ma, and L. Cai, “Indocyanine green-loaded biodegradable tumor targeting nanoprobes for in vitro and in vivo imaging,” Biomaterials 33(22), 5603–5609 (2012).
    [Crossref] [PubMed]
  24. K. Kono, M. Takashima, E. Yuba, A. Harada, Y. Hiramatsu, H. Kitagawa, T. Otani, K. Maruyama, and S. Aoshima, “Multifunctional liposomes having target specificity, temperature-triggered release, and near-infrared fluorescence imaging for tumor-specific chemotherapy,” J. Control. Release 216, 69–77 (2015).
    [Crossref] [PubMed]
  25. J. Zheng, N. Muhanna, R. De Souza, H. Wada, H. Chan, M. K. Akens, T. Anayama, K. Yasufuku, S. Serra, J. Irish, C. Allen, and D. Jaffray, “A multimodal nano agent for image-guided cancer surgery,” Biomaterials 67, 160–168 (2015).
    [Crossref] [PubMed]
  26. A. K. Rengan, M. Jagtap, A. De, R. Banerjee, and R. Srivastava, “Multifunctional gold coated thermo-sensitive liposomes for multimodal imaging and photo-thermal therapy of breast cancer cells,” Nanoscale 6(2), 916–923 (2014).
    [Crossref] [PubMed]
  27. A. Yuan, X. Tang, X. Qiu, K. Jiang, J. Wu, and Y. Hu, “Activatable photodynamic destruction of cancer cells by NIR dye/photosensitizer loaded liposomes,” Chem. Commun. (Camb.) 51(16), 3340–3342 (2015).
    [Crossref] [PubMed]
  28. F. Yan, H. Wu, H. Liu, Z. Deng, H. Liu, W. Duan, X. Liu, and H. Zheng, “Molecular imaging-guided photothermal/photodynamic therapy against tumor by iRGD-modified indocyanine green nanoparticles,” J. Control. Release 224, 217–228 (2016).
    [Crossref] [PubMed]
  29. G. Zhang, F. Liu, B. Zhang, Y. He, J. Luo, and J. Bai, “Imaging of pharmacokinetic rates of indocyanine green in mouse liver with a hybrid fluorescence molecular tomography/x-ray computed tomography system,” J. Biomed. Opt. 18(4), 040505 (2013).
    [Crossref] [PubMed]
  30. X. Liu, X. L. Guo, F. Liu, Y. Zhang, H. Zhang, G. S. Hu, and J. Bai, “Imaging of Indocyanine Green Perfusion in Mouse Liver With Fluorescence Diffuse Optical Tomography,” IEEE Trans. Biomed. Eng. 58, 2139–2143 (2011).
  31. A. Taruttis, S. Morscher, N. C. Burton, D. Razansky, and V. Ntziachristos, “Fast Multispectral Optoacoustic Tomography (MSOT) for Dynamic Imaging of Pharmacokinetics and Biodistribution in Multiple Organs,” PLoS One 7(1), e30491 (2012).
    [Crossref] [PubMed]
  32. S. Patwardhan, S. Bloch, S. Achilefu, and J. Culver, “Time-dependent whole-body fluorescence tomography of probe bio-distributions in mice,” Opt. Express 13(7), 2564–2577 (2005).
    [Crossref] [PubMed]
  33. J. T. Alander, I. Kaartinen, A. Laakso, T. Pätilä, T. Spillmann, V. V. Tuchin, M. Venermo, and P. Välisuo, “A review of indocyanine green fluorescent imaging in surgery,” Int. J. Biomed. Imaging 2012, 940585 (2012).
    [Crossref] [PubMed]
  34. C. M. Leevy, F. Smith, J. Longueville, G. Paumgartner, and M. M. Howard, “Indocyanine green clearance as a test for hepatic function. Evaluation by dichromatic ear densitometry,” JAMA 200(3), 236–240 (1967).
    [Crossref] [PubMed]
  35. R. L. Lindquist, G. Shakhar, D. Dudziak, H. Wardemann, T. Eisenreich, M. L. Dustin, and M. C. Nussenzweig, “Visualizing dendritic cell networks in vivo,” Nat. Immunol. 5(12), 1243–1250 (2004).
    [Crossref] [PubMed]
  36. S. Jung, J. Aliberti, P. Graemmel, M. J. Sunshine, G. W. Kreutzberg, A. Sher, and D. R. Littman, “Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion,” Mol. Cell. Biol. 20(11), 4106–4114 (2000).
    [Crossref] [PubMed]
  37. M. Rajadhyaksha, R. R. Anderson, and R. H. Webb, “Video-rate confocal scanning laser microscope for imaging human tissues in vivo,” Appl. Opt. 38(10), 2105–2115 (1999).
    [Crossref] [PubMed]
  38. I. Veilleux, J. A. Spencer, D. P. Biss, D. Cote, and C. P. Lin, “In vivo cell tracking with video rate multimodality laser scanning microscopy,” IEEE J. Sel. Top. Quantum Electron. 14(1), 10–18 (2008).
    [Crossref]
  39. Y. Hwang, J. Ahn, J. Mun, S. Bae, Y. U. Jeong, N. A. Vinokurov, and P. Kim, “In vivo analysis of THz wave irradiation induced acute inflammatory response in skin by laser-scanning confocal microscopy,” Opt. Express 22(10), 11465–11475 (2014).
    [Crossref] [PubMed]
  40. H. Seo, Y. Hwang, K. Choe, and P. Kim, “In vivo quantitation of injected circulating tumor cells from great saphenous vein based on video-rate confocal microscopy,” Biomed. Opt. Express 6(6), 2158–2167 (2015).
    [Crossref] [PubMed]
  41. K. Choe, J. Y. Jang, I. Park, Y. Kim, S. Ahn, D. Y. Park, Y. K. Hong, K. Alitalo, G. Y. Koh, and P. Kim, “Intravital imaging of intestinal lacteals unveils lipid drainage through contractility,” J. Clin. Invest. 125(11), 4042–4052 (2015).
    [Crossref] [PubMed]
  42. E. Song, H. Seo, K. Choe, Y. Hwang, J. Ahn, S. Ahn, and P. Kim, “Optical clearing based cellular-level 3D visualization of intact lymph node cortex,” Biomed. Opt. Express 6(10), 4154–4164 (2015).
    [Crossref] [PubMed]
  43. F. Heymann and F. Tacke, “Immunology in the liver--from homeostasis to disease,” Nat. Rev. Gastroenterol. Hepatol. 13(2), 88–110 (2016).
    [Crossref] [PubMed]
  44. B. Janssen, J. Debets, P. Leenders, and J. Smits, “Chronic measurement of cardiac output in conscious mice,” Am. J. Physiol. Regul. Integr. Comp. Physiol. 282(3), R928–R935 (2002).
    [Crossref] [PubMed]
  45. L. Prodanov, R. Jindal, S. S. Bale, M. Hegde, W. J. McCarty, I. Golberg, A. Bhushan, M. L. Yarmush, and O. B. Usta, “Long-term maintenance of a microfluidic 3D human liver sinusoid,” Biotechnol. Bioeng. 113(1), 241–246 (2016).
    [Crossref] [PubMed]
  46. J. C. Ryan, K. W. Dunn, and B. S. Decker, “Effects of chronic kidney disease on liver transport: quantitative intravital microscopy of fluorescein transport in the rat liver,” Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(12), R1488–R1492 (2014).
    [Crossref] [PubMed]

2016 (3)

F. Yan, H. Wu, H. Liu, Z. Deng, H. Liu, W. Duan, X. Liu, and H. Zheng, “Molecular imaging-guided photothermal/photodynamic therapy against tumor by iRGD-modified indocyanine green nanoparticles,” J. Control. Release 224, 217–228 (2016).
[Crossref] [PubMed]

F. Heymann and F. Tacke, “Immunology in the liver--from homeostasis to disease,” Nat. Rev. Gastroenterol. Hepatol. 13(2), 88–110 (2016).
[Crossref] [PubMed]

L. Prodanov, R. Jindal, S. S. Bale, M. Hegde, W. J. McCarty, I. Golberg, A. Bhushan, M. L. Yarmush, and O. B. Usta, “Long-term maintenance of a microfluidic 3D human liver sinusoid,” Biotechnol. Bioeng. 113(1), 241–246 (2016).
[Crossref] [PubMed]

2015 (7)

H. Seo, Y. Hwang, K. Choe, and P. Kim, “In vivo quantitation of injected circulating tumor cells from great saphenous vein based on video-rate confocal microscopy,” Biomed. Opt. Express 6(6), 2158–2167 (2015).
[Crossref] [PubMed]

E. Song, H. Seo, K. Choe, Y. Hwang, J. Ahn, S. Ahn, and P. Kim, “Optical clearing based cellular-level 3D visualization of intact lymph node cortex,” Biomed. Opt. Express 6(10), 4154–4164 (2015).
[Crossref] [PubMed]

K. Kono, M. Takashima, E. Yuba, A. Harada, Y. Hiramatsu, H. Kitagawa, T. Otani, K. Maruyama, and S. Aoshima, “Multifunctional liposomes having target specificity, temperature-triggered release, and near-infrared fluorescence imaging for tumor-specific chemotherapy,” J. Control. Release 216, 69–77 (2015).
[Crossref] [PubMed]

J. Zheng, N. Muhanna, R. De Souza, H. Wada, H. Chan, M. K. Akens, T. Anayama, K. Yasufuku, S. Serra, J. Irish, C. Allen, and D. Jaffray, “A multimodal nano agent for image-guided cancer surgery,” Biomaterials 67, 160–168 (2015).
[Crossref] [PubMed]

A. Yuan, X. Tang, X. Qiu, K. Jiang, J. Wu, and Y. Hu, “Activatable photodynamic destruction of cancer cells by NIR dye/photosensitizer loaded liposomes,” Chem. Commun. (Camb.) 51(16), 3340–3342 (2015).
[Crossref] [PubMed]

W. T. Song, Z. H. Tang, D. W. Zhang, N. Burton, W. Driessen, and X. S. Chen, “Comprehensive studies of pharmacokinetics and biodistribution of indocyanine green and liposomal indocyanine green by multispectral optoacoustic tomography,” Rsc Adv 5(5), 3807–3813 (2015).
[Crossref]

K. Choe, J. Y. Jang, I. Park, Y. Kim, S. Ahn, D. Y. Park, Y. K. Hong, K. Alitalo, G. Y. Koh, and P. Kim, “Intravital imaging of intestinal lacteals unveils lipid drainage through contractility,” J. Clin. Invest. 125(11), 4042–4052 (2015).
[Crossref] [PubMed]

2014 (3)

A. K. Rengan, M. Jagtap, A. De, R. Banerjee, and R. Srivastava, “Multifunctional gold coated thermo-sensitive liposomes for multimodal imaging and photo-thermal therapy of breast cancer cells,” Nanoscale 6(2), 916–923 (2014).
[Crossref] [PubMed]

J. C. Ryan, K. W. Dunn, and B. S. Decker, “Effects of chronic kidney disease on liver transport: quantitative intravital microscopy of fluorescein transport in the rat liver,” Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(12), R1488–R1492 (2014).
[Crossref] [PubMed]

Y. Hwang, J. Ahn, J. Mun, S. Bae, Y. U. Jeong, N. A. Vinokurov, and P. Kim, “In vivo analysis of THz wave irradiation induced acute inflammatory response in skin by laser-scanning confocal microscopy,” Opt. Express 22(10), 11465–11475 (2014).
[Crossref] [PubMed]

2013 (2)

S. Kwon, G. D. Agollah, G. Wu, W. Chan, and E. M. Sevick-Muraca, “Direct visualization of changes of lymphatic function and drainage pathways in lymph node metastasis of B16F10 melanoma using near-infrared fluorescence imaging,” Biomed. Opt. Express 4(6), 967–977 (2013).
[Crossref] [PubMed]

G. Zhang, F. Liu, B. Zhang, Y. He, J. Luo, and J. Bai, “Imaging of pharmacokinetic rates of indocyanine green in mouse liver with a hybrid fluorescence molecular tomography/x-ray computed tomography system,” J. Biomed. Opt. 18(4), 040505 (2013).
[Crossref] [PubMed]

2012 (5)

A. Taruttis, S. Morscher, N. C. Burton, D. Razansky, and V. Ntziachristos, “Fast Multispectral Optoacoustic Tomography (MSOT) for Dynamic Imaging of Pharmacokinetics and Biodistribution in Multiple Organs,” PLoS One 7(1), e30491 (2012).
[Crossref] [PubMed]

C. Zheng, M. Zheng, P. Gong, D. Jia, P. Zhang, B. Shi, Z. Sheng, Y. Ma, and L. Cai, “Indocyanine green-loaded biodegradable tumor targeting nanoprobes for in vitro and in vivo imaging,” Biomaterials 33(22), 5603–5609 (2012).
[Crossref] [PubMed]

T. Holmes, A. Invernizzi, S. Larkin, and G. Staurenghi, “Dynamic indocyanine green angiography measurements,” J. Biomed. Opt. 17(11), 116028 (2012).
[Crossref] [PubMed]

W. Piyawattanametha, H. Ra, Z. Qiu, S. Friedland, J. T. C. Liu, K. Loewke, G. S. Kino, O. Solgaard, T. D. Wang, M. J. Mandella, and C. H. Contag, “In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract,” J. Biomed. Opt. 17(2), 021102 (2012).
[Crossref] [PubMed]

J. T. Alander, I. Kaartinen, A. Laakso, T. Pätilä, T. Spillmann, V. V. Tuchin, M. Venermo, and P. Välisuo, “A review of indocyanine green fluorescent imaging in surgery,” Int. J. Biomed. Imaging 2012, 940585 (2012).
[Crossref] [PubMed]

2011 (6)

B. E. Schaafsma, J. S. D. Mieog, M. Hutteman, J. R. van der Vorst, P. J. K. Kuppen, C. W. G. M. Löwik, J. V. Frangioni, C. J. H. van de Velde, and A. L. Vahrmeijer, “The Clinical Use of Indocyanine Green as a near-Infrared Fluorescent Contrast Agent for Image-Guided Oncologic Surgery,” J. Surg. Oncol. 104(3), 323–332 (2011).
[Crossref] [PubMed]

H. Skvara, H. Kittler, J. A. Schmid, U. Plut, and C. Jonak, “In vivo fluorescence confocal microscopy: indocyanine green enhances the contrast of epidermal and dermal structures,” J. Biomed. Opt. 16(9), 096010 (2011).
[Crossref] [PubMed]

M. Choi, K. Choi, S. W. Ryu, J. Lee, and C. Choi, “Dynamic fluorescence imaging for multiparametric measurement of tumor vasculature,” J. Biomed. Opt. 16(4), 046008 (2011).
[Crossref] [PubMed]

X. Liu, X. L. Guo, F. Liu, Y. Zhang, H. Zhang, G. S. Hu, and J. Bai, “Imaging of Indocyanine Green Perfusion in Mouse Liver With Fluorescence Diffuse Optical Tomography,” IEEE Trans. Biomed. Eng. 58, 2139–2143 (2011).

N. L. Martirosyan, D. D. Cavalcanti, J. M. Eschbacher, P. M. Delaney, A. C. Scheck, M. G. Abdelwahab, P. Nakaji, R. F. Spetzler, and M. C. Preul, “Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor Laboratory investigation,” J. Neurosurg. 115(6), 1131–1138 (2011).
[Crossref] [PubMed]

C. Habermehl, C. H. Schmitz, and J. Steinbrink, “Contrast enhanced high-resolution diffuse optical tomography of the human brain using ICG,” Opt. Express 19(19), 18636–18644 (2011).
[Crossref] [PubMed]

2010 (1)

S. T. Proulx, P. Luciani, S. Derzsi, M. Rinderknecht, V. Mumprecht, J. C. Leroux, and M. Detmar, “Quantitative Imaging of Lymphatic Function with Liposomal Indocyanine Green,” Cancer Res. 70(18), 7053–7062 (2010).
[Crossref] [PubMed]

2009 (2)

Y. Kang, M. Choi, J. Lee, G. Y. Koh, K. Kwon, and C. Choi, “Quantitative Analysis of Peripheral Tissue Perfusion Using Spatiotemporal Molecular Dynamics,” PLoS One 4(1), e4275 (2009).
[Crossref] [PubMed]

A. M. Smith, M. C. Mancini, and S. Nie, “Bioimaging: Second window for in vivo imaging,” Nat. Nanotechnol. 4(11), 710–711 (2009).
[Crossref] [PubMed]

2008 (2)

N. Unno, M. Nishiyama, M. Suzuki, N. Yamamoto, K. Inuzuka, D. Sagara, H. Tanaka, and H. Konno, “Quantitative lymph imaging for assessment of lymph function using indocyanine green fluorescence lymphography,” Eur. J. Vasc. Endovasc. Surg. 36(2), 230–236 (2008).
[Crossref] [PubMed]

I. Veilleux, J. A. Spencer, D. P. Biss, D. Cote, and C. P. Lin, “In vivo cell tracking with video rate multimodality laser scanning microscopy,” IEEE J. Sel. Top. Quantum Electron. 14(1), 10–18 (2008).
[Crossref]

2007 (1)

R. Sharma, W. Wang, J. C. Rasmussen, A. Joshi, J. P. Houston, K. E. Adams, A. Cameron, S. Ke, S. Kwon, M. E. Mawad, and E. M. Sevick-Muraca, “Quantitative imaging of lymph function,” Am. J. Physiol. Heart Circ. Physiol. 292(6), H3109–H3118 (2007).
[Crossref] [PubMed]

2005 (1)

2004 (1)

R. L. Lindquist, G. Shakhar, D. Dudziak, H. Wardemann, T. Eisenreich, M. L. Dustin, and M. C. Nussenzweig, “Visualizing dendritic cell networks in vivo,” Nat. Immunol. 5(12), 1243–1250 (2004).
[Crossref] [PubMed]

2003 (2)

J. V. Frangioni, “In vivo near-infrared fluorescence imaging,” Curr. Opin. Chem. Biol. 7(5), 626–634 (2003).
[Crossref] [PubMed]

V. Ntziachristos, C. Bremer, and R. Weissleder, “Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging,” Eur. Radiol. 13(1), 195–208 (2003).
[PubMed]

2002 (3)

O. Okochi, T. Kaneko, H. Sugimoto, S. Inoue, S. Takeda, and A. Nakao, “ICG pulse spectrophotometry for perioperative liver function in hepatectomy,” J. Surg. Res. 103(1), 109–113 (2002).
[Crossref] [PubMed]

C. Holm, M. Mayr, E. Höfter, A. Becker, U. J. Pfeiffer, and W. Mühlbauer, “Intraoperative evaluation of skin-flap viability using laser-induced fluorescence of indocyanine green,” Br. J. Plast. Surg. 55(8), 635–644 (2002).
[Crossref] [PubMed]

B. Janssen, J. Debets, P. Leenders, and J. Smits, “Chronic measurement of cardiac output in conscious mice,” Am. J. Physiol. Regul. Integr. Comp. Physiol. 282(3), R928–R935 (2002).
[Crossref] [PubMed]

2001 (1)

R. Weissleder, “A clearer vision for in vivo imaging,” Nat. Biotechnol. 19(4), 316–317 (2001).
[Crossref] [PubMed]

2000 (2)

T. Desmettre, J. M. Devoisselle, and S. Mordon, “Fluorescence properties and metabolic features of indocyanine green (ICG) as related to angiography,” Surv. Ophthalmol. 45(1), 15–27 (2000).
[Crossref] [PubMed]

S. Jung, J. Aliberti, P. Graemmel, M. J. Sunshine, G. W. Kreutzberg, A. Sher, and D. R. Littman, “Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion,” Mol. Cell. Biol. 20(11), 4106–4114 (2000).
[Crossref] [PubMed]

1999 (1)

1997 (1)

T. Iijima, T. Aoyagi, Y. Iwao, J. Masuda, M. Fuse, N. Kobayashi, and H. Sankawa, “Cardiac output and circulating blood volume analysis by pulse dye-densitometry,” J. Clin. Monit. 13(2), 81–89 (1997).
[Crossref] [PubMed]

1988 (1)

A. Gabizon and D. Papahadjopoulos, “Liposome Formulations with Prolonged Circulation Time in Blood and Enhanced Uptake by Tumors,” Proc. Natl. Acad. Sci. U.S.A. 85(18), 6949–6953 (1988).
[Crossref] [PubMed]

1967 (1)

C. M. Leevy, F. Smith, J. Longueville, G. Paumgartner, and M. M. Howard, “Indocyanine green clearance as a test for hepatic function. Evaluation by dichromatic ear densitometry,” JAMA 200(3), 236–240 (1967).
[Crossref] [PubMed]

Abdelwahab, M. G.

N. L. Martirosyan, D. D. Cavalcanti, J. M. Eschbacher, P. M. Delaney, A. C. Scheck, M. G. Abdelwahab, P. Nakaji, R. F. Spetzler, and M. C. Preul, “Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor Laboratory investigation,” J. Neurosurg. 115(6), 1131–1138 (2011).
[Crossref] [PubMed]

Achilefu, S.

Adams, K. E.

R. Sharma, W. Wang, J. C. Rasmussen, A. Joshi, J. P. Houston, K. E. Adams, A. Cameron, S. Ke, S. Kwon, M. E. Mawad, and E. M. Sevick-Muraca, “Quantitative imaging of lymph function,” Am. J. Physiol. Heart Circ. Physiol. 292(6), H3109–H3118 (2007).
[Crossref] [PubMed]

Agollah, G. D.

Ahn, J.

Ahn, S.

E. Song, H. Seo, K. Choe, Y. Hwang, J. Ahn, S. Ahn, and P. Kim, “Optical clearing based cellular-level 3D visualization of intact lymph node cortex,” Biomed. Opt. Express 6(10), 4154–4164 (2015).
[Crossref] [PubMed]

K. Choe, J. Y. Jang, I. Park, Y. Kim, S. Ahn, D. Y. Park, Y. K. Hong, K. Alitalo, G. Y. Koh, and P. Kim, “Intravital imaging of intestinal lacteals unveils lipid drainage through contractility,” J. Clin. Invest. 125(11), 4042–4052 (2015).
[Crossref] [PubMed]

Akens, M. K.

J. Zheng, N. Muhanna, R. De Souza, H. Wada, H. Chan, M. K. Akens, T. Anayama, K. Yasufuku, S. Serra, J. Irish, C. Allen, and D. Jaffray, “A multimodal nano agent for image-guided cancer surgery,” Biomaterials 67, 160–168 (2015).
[Crossref] [PubMed]

Alander, J. T.

J. T. Alander, I. Kaartinen, A. Laakso, T. Pätilä, T. Spillmann, V. V. Tuchin, M. Venermo, and P. Välisuo, “A review of indocyanine green fluorescent imaging in surgery,” Int. J. Biomed. Imaging 2012, 940585 (2012).
[Crossref] [PubMed]

Aliberti, J.

S. Jung, J. Aliberti, P. Graemmel, M. J. Sunshine, G. W. Kreutzberg, A. Sher, and D. R. Littman, “Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion,” Mol. Cell. Biol. 20(11), 4106–4114 (2000).
[Crossref] [PubMed]

Alitalo, K.

K. Choe, J. Y. Jang, I. Park, Y. Kim, S. Ahn, D. Y. Park, Y. K. Hong, K. Alitalo, G. Y. Koh, and P. Kim, “Intravital imaging of intestinal lacteals unveils lipid drainage through contractility,” J. Clin. Invest. 125(11), 4042–4052 (2015).
[Crossref] [PubMed]

Allen, C.

J. Zheng, N. Muhanna, R. De Souza, H. Wada, H. Chan, M. K. Akens, T. Anayama, K. Yasufuku, S. Serra, J. Irish, C. Allen, and D. Jaffray, “A multimodal nano agent for image-guided cancer surgery,” Biomaterials 67, 160–168 (2015).
[Crossref] [PubMed]

Anayama, T.

J. Zheng, N. Muhanna, R. De Souza, H. Wada, H. Chan, M. K. Akens, T. Anayama, K. Yasufuku, S. Serra, J. Irish, C. Allen, and D. Jaffray, “A multimodal nano agent for image-guided cancer surgery,” Biomaterials 67, 160–168 (2015).
[Crossref] [PubMed]

Anderson, R. R.

Aoshima, S.

K. Kono, M. Takashima, E. Yuba, A. Harada, Y. Hiramatsu, H. Kitagawa, T. Otani, K. Maruyama, and S. Aoshima, “Multifunctional liposomes having target specificity, temperature-triggered release, and near-infrared fluorescence imaging for tumor-specific chemotherapy,” J. Control. Release 216, 69–77 (2015).
[Crossref] [PubMed]

Aoyagi, T.

T. Iijima, T. Aoyagi, Y. Iwao, J. Masuda, M. Fuse, N. Kobayashi, and H. Sankawa, “Cardiac output and circulating blood volume analysis by pulse dye-densitometry,” J. Clin. Monit. 13(2), 81–89 (1997).
[Crossref] [PubMed]

Bae, S.

Bai, J.

G. Zhang, F. Liu, B. Zhang, Y. He, J. Luo, and J. Bai, “Imaging of pharmacokinetic rates of indocyanine green in mouse liver with a hybrid fluorescence molecular tomography/x-ray computed tomography system,” J. Biomed. Opt. 18(4), 040505 (2013).
[Crossref] [PubMed]

X. Liu, X. L. Guo, F. Liu, Y. Zhang, H. Zhang, G. S. Hu, and J. Bai, “Imaging of Indocyanine Green Perfusion in Mouse Liver With Fluorescence Diffuse Optical Tomography,” IEEE Trans. Biomed. Eng. 58, 2139–2143 (2011).

Bale, S. S.

L. Prodanov, R. Jindal, S. S. Bale, M. Hegde, W. J. McCarty, I. Golberg, A. Bhushan, M. L. Yarmush, and O. B. Usta, “Long-term maintenance of a microfluidic 3D human liver sinusoid,” Biotechnol. Bioeng. 113(1), 241–246 (2016).
[Crossref] [PubMed]

Banerjee, R.

A. K. Rengan, M. Jagtap, A. De, R. Banerjee, and R. Srivastava, “Multifunctional gold coated thermo-sensitive liposomes for multimodal imaging and photo-thermal therapy of breast cancer cells,” Nanoscale 6(2), 916–923 (2014).
[Crossref] [PubMed]

Becker, A.

C. Holm, M. Mayr, E. Höfter, A. Becker, U. J. Pfeiffer, and W. Mühlbauer, “Intraoperative evaluation of skin-flap viability using laser-induced fluorescence of indocyanine green,” Br. J. Plast. Surg. 55(8), 635–644 (2002).
[Crossref] [PubMed]

Bhushan, A.

L. Prodanov, R. Jindal, S. S. Bale, M. Hegde, W. J. McCarty, I. Golberg, A. Bhushan, M. L. Yarmush, and O. B. Usta, “Long-term maintenance of a microfluidic 3D human liver sinusoid,” Biotechnol. Bioeng. 113(1), 241–246 (2016).
[Crossref] [PubMed]

Biss, D. P.

I. Veilleux, J. A. Spencer, D. P. Biss, D. Cote, and C. P. Lin, “In vivo cell tracking with video rate multimodality laser scanning microscopy,” IEEE J. Sel. Top. Quantum Electron. 14(1), 10–18 (2008).
[Crossref]

Bloch, S.

Bremer, C.

V. Ntziachristos, C. Bremer, and R. Weissleder, “Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging,” Eur. Radiol. 13(1), 195–208 (2003).
[PubMed]

Burton, N.

W. T. Song, Z. H. Tang, D. W. Zhang, N. Burton, W. Driessen, and X. S. Chen, “Comprehensive studies of pharmacokinetics and biodistribution of indocyanine green and liposomal indocyanine green by multispectral optoacoustic tomography,” Rsc Adv 5(5), 3807–3813 (2015).
[Crossref]

Burton, N. C.

A. Taruttis, S. Morscher, N. C. Burton, D. Razansky, and V. Ntziachristos, “Fast Multispectral Optoacoustic Tomography (MSOT) for Dynamic Imaging of Pharmacokinetics and Biodistribution in Multiple Organs,” PLoS One 7(1), e30491 (2012).
[Crossref] [PubMed]

Cai, L.

C. Zheng, M. Zheng, P. Gong, D. Jia, P. Zhang, B. Shi, Z. Sheng, Y. Ma, and L. Cai, “Indocyanine green-loaded biodegradable tumor targeting nanoprobes for in vitro and in vivo imaging,” Biomaterials 33(22), 5603–5609 (2012).
[Crossref] [PubMed]

Cameron, A.

R. Sharma, W. Wang, J. C. Rasmussen, A. Joshi, J. P. Houston, K. E. Adams, A. Cameron, S. Ke, S. Kwon, M. E. Mawad, and E. M. Sevick-Muraca, “Quantitative imaging of lymph function,” Am. J. Physiol. Heart Circ. Physiol. 292(6), H3109–H3118 (2007).
[Crossref] [PubMed]

Cavalcanti, D. D.

N. L. Martirosyan, D. D. Cavalcanti, J. M. Eschbacher, P. M. Delaney, A. C. Scheck, M. G. Abdelwahab, P. Nakaji, R. F. Spetzler, and M. C. Preul, “Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor Laboratory investigation,” J. Neurosurg. 115(6), 1131–1138 (2011).
[Crossref] [PubMed]

Chan, H.

J. Zheng, N. Muhanna, R. De Souza, H. Wada, H. Chan, M. K. Akens, T. Anayama, K. Yasufuku, S. Serra, J. Irish, C. Allen, and D. Jaffray, “A multimodal nano agent for image-guided cancer surgery,” Biomaterials 67, 160–168 (2015).
[Crossref] [PubMed]

Chan, W.

Chen, X. S.

W. T. Song, Z. H. Tang, D. W. Zhang, N. Burton, W. Driessen, and X. S. Chen, “Comprehensive studies of pharmacokinetics and biodistribution of indocyanine green and liposomal indocyanine green by multispectral optoacoustic tomography,” Rsc Adv 5(5), 3807–3813 (2015).
[Crossref]

Choe, K.

Choi, C.

M. Choi, K. Choi, S. W. Ryu, J. Lee, and C. Choi, “Dynamic fluorescence imaging for multiparametric measurement of tumor vasculature,” J. Biomed. Opt. 16(4), 046008 (2011).
[Crossref] [PubMed]

Y. Kang, M. Choi, J. Lee, G. Y. Koh, K. Kwon, and C. Choi, “Quantitative Analysis of Peripheral Tissue Perfusion Using Spatiotemporal Molecular Dynamics,” PLoS One 4(1), e4275 (2009).
[Crossref] [PubMed]

Choi, K.

M. Choi, K. Choi, S. W. Ryu, J. Lee, and C. Choi, “Dynamic fluorescence imaging for multiparametric measurement of tumor vasculature,” J. Biomed. Opt. 16(4), 046008 (2011).
[Crossref] [PubMed]

Choi, M.

M. Choi, K. Choi, S. W. Ryu, J. Lee, and C. Choi, “Dynamic fluorescence imaging for multiparametric measurement of tumor vasculature,” J. Biomed. Opt. 16(4), 046008 (2011).
[Crossref] [PubMed]

Y. Kang, M. Choi, J. Lee, G. Y. Koh, K. Kwon, and C. Choi, “Quantitative Analysis of Peripheral Tissue Perfusion Using Spatiotemporal Molecular Dynamics,” PLoS One 4(1), e4275 (2009).
[Crossref] [PubMed]

Contag, C. H.

W. Piyawattanametha, H. Ra, Z. Qiu, S. Friedland, J. T. C. Liu, K. Loewke, G. S. Kino, O. Solgaard, T. D. Wang, M. J. Mandella, and C. H. Contag, “In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract,” J. Biomed. Opt. 17(2), 021102 (2012).
[Crossref] [PubMed]

Cote, D.

I. Veilleux, J. A. Spencer, D. P. Biss, D. Cote, and C. P. Lin, “In vivo cell tracking with video rate multimodality laser scanning microscopy,” IEEE J. Sel. Top. Quantum Electron. 14(1), 10–18 (2008).
[Crossref]

Culver, J.

De, A.

A. K. Rengan, M. Jagtap, A. De, R. Banerjee, and R. Srivastava, “Multifunctional gold coated thermo-sensitive liposomes for multimodal imaging and photo-thermal therapy of breast cancer cells,” Nanoscale 6(2), 916–923 (2014).
[Crossref] [PubMed]

De Souza, R.

J. Zheng, N. Muhanna, R. De Souza, H. Wada, H. Chan, M. K. Akens, T. Anayama, K. Yasufuku, S. Serra, J. Irish, C. Allen, and D. Jaffray, “A multimodal nano agent for image-guided cancer surgery,” Biomaterials 67, 160–168 (2015).
[Crossref] [PubMed]

Debets, J.

B. Janssen, J. Debets, P. Leenders, and J. Smits, “Chronic measurement of cardiac output in conscious mice,” Am. J. Physiol. Regul. Integr. Comp. Physiol. 282(3), R928–R935 (2002).
[Crossref] [PubMed]

Decker, B. S.

J. C. Ryan, K. W. Dunn, and B. S. Decker, “Effects of chronic kidney disease on liver transport: quantitative intravital microscopy of fluorescein transport in the rat liver,” Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(12), R1488–R1492 (2014).
[Crossref] [PubMed]

Delaney, P. M.

N. L. Martirosyan, D. D. Cavalcanti, J. M. Eschbacher, P. M. Delaney, A. C. Scheck, M. G. Abdelwahab, P. Nakaji, R. F. Spetzler, and M. C. Preul, “Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor Laboratory investigation,” J. Neurosurg. 115(6), 1131–1138 (2011).
[Crossref] [PubMed]

Deng, Z.

F. Yan, H. Wu, H. Liu, Z. Deng, H. Liu, W. Duan, X. Liu, and H. Zheng, “Molecular imaging-guided photothermal/photodynamic therapy against tumor by iRGD-modified indocyanine green nanoparticles,” J. Control. Release 224, 217–228 (2016).
[Crossref] [PubMed]

Derzsi, S.

S. T. Proulx, P. Luciani, S. Derzsi, M. Rinderknecht, V. Mumprecht, J. C. Leroux, and M. Detmar, “Quantitative Imaging of Lymphatic Function with Liposomal Indocyanine Green,” Cancer Res. 70(18), 7053–7062 (2010).
[Crossref] [PubMed]

Desmettre, T.

T. Desmettre, J. M. Devoisselle, and S. Mordon, “Fluorescence properties and metabolic features of indocyanine green (ICG) as related to angiography,” Surv. Ophthalmol. 45(1), 15–27 (2000).
[Crossref] [PubMed]

Detmar, M.

S. T. Proulx, P. Luciani, S. Derzsi, M. Rinderknecht, V. Mumprecht, J. C. Leroux, and M. Detmar, “Quantitative Imaging of Lymphatic Function with Liposomal Indocyanine Green,” Cancer Res. 70(18), 7053–7062 (2010).
[Crossref] [PubMed]

Devoisselle, J. M.

T. Desmettre, J. M. Devoisselle, and S. Mordon, “Fluorescence properties and metabolic features of indocyanine green (ICG) as related to angiography,” Surv. Ophthalmol. 45(1), 15–27 (2000).
[Crossref] [PubMed]

Driessen, W.

W. T. Song, Z. H. Tang, D. W. Zhang, N. Burton, W. Driessen, and X. S. Chen, “Comprehensive studies of pharmacokinetics and biodistribution of indocyanine green and liposomal indocyanine green by multispectral optoacoustic tomography,” Rsc Adv 5(5), 3807–3813 (2015).
[Crossref]

Duan, W.

F. Yan, H. Wu, H. Liu, Z. Deng, H. Liu, W. Duan, X. Liu, and H. Zheng, “Molecular imaging-guided photothermal/photodynamic therapy against tumor by iRGD-modified indocyanine green nanoparticles,” J. Control. Release 224, 217–228 (2016).
[Crossref] [PubMed]

Dudziak, D.

R. L. Lindquist, G. Shakhar, D. Dudziak, H. Wardemann, T. Eisenreich, M. L. Dustin, and M. C. Nussenzweig, “Visualizing dendritic cell networks in vivo,” Nat. Immunol. 5(12), 1243–1250 (2004).
[Crossref] [PubMed]

Dunn, K. W.

J. C. Ryan, K. W. Dunn, and B. S. Decker, “Effects of chronic kidney disease on liver transport: quantitative intravital microscopy of fluorescein transport in the rat liver,” Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(12), R1488–R1492 (2014).
[Crossref] [PubMed]

Dustin, M. L.

R. L. Lindquist, G. Shakhar, D. Dudziak, H. Wardemann, T. Eisenreich, M. L. Dustin, and M. C. Nussenzweig, “Visualizing dendritic cell networks in vivo,” Nat. Immunol. 5(12), 1243–1250 (2004).
[Crossref] [PubMed]

Eisenreich, T.

R. L. Lindquist, G. Shakhar, D. Dudziak, H. Wardemann, T. Eisenreich, M. L. Dustin, and M. C. Nussenzweig, “Visualizing dendritic cell networks in vivo,” Nat. Immunol. 5(12), 1243–1250 (2004).
[Crossref] [PubMed]

Eschbacher, J. M.

N. L. Martirosyan, D. D. Cavalcanti, J. M. Eschbacher, P. M. Delaney, A. C. Scheck, M. G. Abdelwahab, P. Nakaji, R. F. Spetzler, and M. C. Preul, “Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor Laboratory investigation,” J. Neurosurg. 115(6), 1131–1138 (2011).
[Crossref] [PubMed]

Frangioni, J. V.

B. E. Schaafsma, J. S. D. Mieog, M. Hutteman, J. R. van der Vorst, P. J. K. Kuppen, C. W. G. M. Löwik, J. V. Frangioni, C. J. H. van de Velde, and A. L. Vahrmeijer, “The Clinical Use of Indocyanine Green as a near-Infrared Fluorescent Contrast Agent for Image-Guided Oncologic Surgery,” J. Surg. Oncol. 104(3), 323–332 (2011).
[Crossref] [PubMed]

J. V. Frangioni, “In vivo near-infrared fluorescence imaging,” Curr. Opin. Chem. Biol. 7(5), 626–634 (2003).
[Crossref] [PubMed]

Friedland, S.

W. Piyawattanametha, H. Ra, Z. Qiu, S. Friedland, J. T. C. Liu, K. Loewke, G. S. Kino, O. Solgaard, T. D. Wang, M. J. Mandella, and C. H. Contag, “In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract,” J. Biomed. Opt. 17(2), 021102 (2012).
[Crossref] [PubMed]

Fuse, M.

T. Iijima, T. Aoyagi, Y. Iwao, J. Masuda, M. Fuse, N. Kobayashi, and H. Sankawa, “Cardiac output and circulating blood volume analysis by pulse dye-densitometry,” J. Clin. Monit. 13(2), 81–89 (1997).
[Crossref] [PubMed]

Gabizon, A.

A. Gabizon and D. Papahadjopoulos, “Liposome Formulations with Prolonged Circulation Time in Blood and Enhanced Uptake by Tumors,” Proc. Natl. Acad. Sci. U.S.A. 85(18), 6949–6953 (1988).
[Crossref] [PubMed]

Golberg, I.

L. Prodanov, R. Jindal, S. S. Bale, M. Hegde, W. J. McCarty, I. Golberg, A. Bhushan, M. L. Yarmush, and O. B. Usta, “Long-term maintenance of a microfluidic 3D human liver sinusoid,” Biotechnol. Bioeng. 113(1), 241–246 (2016).
[Crossref] [PubMed]

Gong, P.

C. Zheng, M. Zheng, P. Gong, D. Jia, P. Zhang, B. Shi, Z. Sheng, Y. Ma, and L. Cai, “Indocyanine green-loaded biodegradable tumor targeting nanoprobes for in vitro and in vivo imaging,” Biomaterials 33(22), 5603–5609 (2012).
[Crossref] [PubMed]

Graemmel, P.

S. Jung, J. Aliberti, P. Graemmel, M. J. Sunshine, G. W. Kreutzberg, A. Sher, and D. R. Littman, “Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion,” Mol. Cell. Biol. 20(11), 4106–4114 (2000).
[Crossref] [PubMed]

Guo, X. L.

X. Liu, X. L. Guo, F. Liu, Y. Zhang, H. Zhang, G. S. Hu, and J. Bai, “Imaging of Indocyanine Green Perfusion in Mouse Liver With Fluorescence Diffuse Optical Tomography,” IEEE Trans. Biomed. Eng. 58, 2139–2143 (2011).

Habermehl, C.

Harada, A.

K. Kono, M. Takashima, E. Yuba, A. Harada, Y. Hiramatsu, H. Kitagawa, T. Otani, K. Maruyama, and S. Aoshima, “Multifunctional liposomes having target specificity, temperature-triggered release, and near-infrared fluorescence imaging for tumor-specific chemotherapy,” J. Control. Release 216, 69–77 (2015).
[Crossref] [PubMed]

He, Y.

G. Zhang, F. Liu, B. Zhang, Y. He, J. Luo, and J. Bai, “Imaging of pharmacokinetic rates of indocyanine green in mouse liver with a hybrid fluorescence molecular tomography/x-ray computed tomography system,” J. Biomed. Opt. 18(4), 040505 (2013).
[Crossref] [PubMed]

Hegde, M.

L. Prodanov, R. Jindal, S. S. Bale, M. Hegde, W. J. McCarty, I. Golberg, A. Bhushan, M. L. Yarmush, and O. B. Usta, “Long-term maintenance of a microfluidic 3D human liver sinusoid,” Biotechnol. Bioeng. 113(1), 241–246 (2016).
[Crossref] [PubMed]

Heymann, F.

F. Heymann and F. Tacke, “Immunology in the liver--from homeostasis to disease,” Nat. Rev. Gastroenterol. Hepatol. 13(2), 88–110 (2016).
[Crossref] [PubMed]

Hiramatsu, Y.

K. Kono, M. Takashima, E. Yuba, A. Harada, Y. Hiramatsu, H. Kitagawa, T. Otani, K. Maruyama, and S. Aoshima, “Multifunctional liposomes having target specificity, temperature-triggered release, and near-infrared fluorescence imaging for tumor-specific chemotherapy,” J. Control. Release 216, 69–77 (2015).
[Crossref] [PubMed]

Höfter, E.

C. Holm, M. Mayr, E. Höfter, A. Becker, U. J. Pfeiffer, and W. Mühlbauer, “Intraoperative evaluation of skin-flap viability using laser-induced fluorescence of indocyanine green,” Br. J. Plast. Surg. 55(8), 635–644 (2002).
[Crossref] [PubMed]

Holm, C.

C. Holm, M. Mayr, E. Höfter, A. Becker, U. J. Pfeiffer, and W. Mühlbauer, “Intraoperative evaluation of skin-flap viability using laser-induced fluorescence of indocyanine green,” Br. J. Plast. Surg. 55(8), 635–644 (2002).
[Crossref] [PubMed]

Holmes, T.

T. Holmes, A. Invernizzi, S. Larkin, and G. Staurenghi, “Dynamic indocyanine green angiography measurements,” J. Biomed. Opt. 17(11), 116028 (2012).
[Crossref] [PubMed]

Hong, Y. K.

K. Choe, J. Y. Jang, I. Park, Y. Kim, S. Ahn, D. Y. Park, Y. K. Hong, K. Alitalo, G. Y. Koh, and P. Kim, “Intravital imaging of intestinal lacteals unveils lipid drainage through contractility,” J. Clin. Invest. 125(11), 4042–4052 (2015).
[Crossref] [PubMed]

Houston, J. P.

R. Sharma, W. Wang, J. C. Rasmussen, A. Joshi, J. P. Houston, K. E. Adams, A. Cameron, S. Ke, S. Kwon, M. E. Mawad, and E. M. Sevick-Muraca, “Quantitative imaging of lymph function,” Am. J. Physiol. Heart Circ. Physiol. 292(6), H3109–H3118 (2007).
[Crossref] [PubMed]

Howard, M. M.

C. M. Leevy, F. Smith, J. Longueville, G. Paumgartner, and M. M. Howard, “Indocyanine green clearance as a test for hepatic function. Evaluation by dichromatic ear densitometry,” JAMA 200(3), 236–240 (1967).
[Crossref] [PubMed]

Hu, G. S.

X. Liu, X. L. Guo, F. Liu, Y. Zhang, H. Zhang, G. S. Hu, and J. Bai, “Imaging of Indocyanine Green Perfusion in Mouse Liver With Fluorescence Diffuse Optical Tomography,” IEEE Trans. Biomed. Eng. 58, 2139–2143 (2011).

Hu, Y.

A. Yuan, X. Tang, X. Qiu, K. Jiang, J. Wu, and Y. Hu, “Activatable photodynamic destruction of cancer cells by NIR dye/photosensitizer loaded liposomes,” Chem. Commun. (Camb.) 51(16), 3340–3342 (2015).
[Crossref] [PubMed]

Hutteman, M.

B. E. Schaafsma, J. S. D. Mieog, M. Hutteman, J. R. van der Vorst, P. J. K. Kuppen, C. W. G. M. Löwik, J. V. Frangioni, C. J. H. van de Velde, and A. L. Vahrmeijer, “The Clinical Use of Indocyanine Green as a near-Infrared Fluorescent Contrast Agent for Image-Guided Oncologic Surgery,” J. Surg. Oncol. 104(3), 323–332 (2011).
[Crossref] [PubMed]

Hwang, Y.

Iijima, T.

T. Iijima, T. Aoyagi, Y. Iwao, J. Masuda, M. Fuse, N. Kobayashi, and H. Sankawa, “Cardiac output and circulating blood volume analysis by pulse dye-densitometry,” J. Clin. Monit. 13(2), 81–89 (1997).
[Crossref] [PubMed]

Inoue, S.

O. Okochi, T. Kaneko, H. Sugimoto, S. Inoue, S. Takeda, and A. Nakao, “ICG pulse spectrophotometry for perioperative liver function in hepatectomy,” J. Surg. Res. 103(1), 109–113 (2002).
[Crossref] [PubMed]

Inuzuka, K.

N. Unno, M. Nishiyama, M. Suzuki, N. Yamamoto, K. Inuzuka, D. Sagara, H. Tanaka, and H. Konno, “Quantitative lymph imaging for assessment of lymph function using indocyanine green fluorescence lymphography,” Eur. J. Vasc. Endovasc. Surg. 36(2), 230–236 (2008).
[Crossref] [PubMed]

Invernizzi, A.

T. Holmes, A. Invernizzi, S. Larkin, and G. Staurenghi, “Dynamic indocyanine green angiography measurements,” J. Biomed. Opt. 17(11), 116028 (2012).
[Crossref] [PubMed]

Irish, J.

J. Zheng, N. Muhanna, R. De Souza, H. Wada, H. Chan, M. K. Akens, T. Anayama, K. Yasufuku, S. Serra, J. Irish, C. Allen, and D. Jaffray, “A multimodal nano agent for image-guided cancer surgery,” Biomaterials 67, 160–168 (2015).
[Crossref] [PubMed]

Iwao, Y.

T. Iijima, T. Aoyagi, Y. Iwao, J. Masuda, M. Fuse, N. Kobayashi, and H. Sankawa, “Cardiac output and circulating blood volume analysis by pulse dye-densitometry,” J. Clin. Monit. 13(2), 81–89 (1997).
[Crossref] [PubMed]

Jaffray, D.

J. Zheng, N. Muhanna, R. De Souza, H. Wada, H. Chan, M. K. Akens, T. Anayama, K. Yasufuku, S. Serra, J. Irish, C. Allen, and D. Jaffray, “A multimodal nano agent for image-guided cancer surgery,” Biomaterials 67, 160–168 (2015).
[Crossref] [PubMed]

Jagtap, M.

A. K. Rengan, M. Jagtap, A. De, R. Banerjee, and R. Srivastava, “Multifunctional gold coated thermo-sensitive liposomes for multimodal imaging and photo-thermal therapy of breast cancer cells,” Nanoscale 6(2), 916–923 (2014).
[Crossref] [PubMed]

Jang, J. Y.

K. Choe, J. Y. Jang, I. Park, Y. Kim, S. Ahn, D. Y. Park, Y. K. Hong, K. Alitalo, G. Y. Koh, and P. Kim, “Intravital imaging of intestinal lacteals unveils lipid drainage through contractility,” J. Clin. Invest. 125(11), 4042–4052 (2015).
[Crossref] [PubMed]

Janssen, B.

B. Janssen, J. Debets, P. Leenders, and J. Smits, “Chronic measurement of cardiac output in conscious mice,” Am. J. Physiol. Regul. Integr. Comp. Physiol. 282(3), R928–R935 (2002).
[Crossref] [PubMed]

Jeong, Y. U.

Jia, D.

C. Zheng, M. Zheng, P. Gong, D. Jia, P. Zhang, B. Shi, Z. Sheng, Y. Ma, and L. Cai, “Indocyanine green-loaded biodegradable tumor targeting nanoprobes for in vitro and in vivo imaging,” Biomaterials 33(22), 5603–5609 (2012).
[Crossref] [PubMed]

Jiang, K.

A. Yuan, X. Tang, X. Qiu, K. Jiang, J. Wu, and Y. Hu, “Activatable photodynamic destruction of cancer cells by NIR dye/photosensitizer loaded liposomes,” Chem. Commun. (Camb.) 51(16), 3340–3342 (2015).
[Crossref] [PubMed]

Jindal, R.

L. Prodanov, R. Jindal, S. S. Bale, M. Hegde, W. J. McCarty, I. Golberg, A. Bhushan, M. L. Yarmush, and O. B. Usta, “Long-term maintenance of a microfluidic 3D human liver sinusoid,” Biotechnol. Bioeng. 113(1), 241–246 (2016).
[Crossref] [PubMed]

Jonak, C.

H. Skvara, H. Kittler, J. A. Schmid, U. Plut, and C. Jonak, “In vivo fluorescence confocal microscopy: indocyanine green enhances the contrast of epidermal and dermal structures,” J. Biomed. Opt. 16(9), 096010 (2011).
[Crossref] [PubMed]

Joshi, A.

R. Sharma, W. Wang, J. C. Rasmussen, A. Joshi, J. P. Houston, K. E. Adams, A. Cameron, S. Ke, S. Kwon, M. E. Mawad, and E. M. Sevick-Muraca, “Quantitative imaging of lymph function,” Am. J. Physiol. Heart Circ. Physiol. 292(6), H3109–H3118 (2007).
[Crossref] [PubMed]

Jung, S.

S. Jung, J. Aliberti, P. Graemmel, M. J. Sunshine, G. W. Kreutzberg, A. Sher, and D. R. Littman, “Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion,” Mol. Cell. Biol. 20(11), 4106–4114 (2000).
[Crossref] [PubMed]

Kaartinen, I.

J. T. Alander, I. Kaartinen, A. Laakso, T. Pätilä, T. Spillmann, V. V. Tuchin, M. Venermo, and P. Välisuo, “A review of indocyanine green fluorescent imaging in surgery,” Int. J. Biomed. Imaging 2012, 940585 (2012).
[Crossref] [PubMed]

Kaneko, T.

O. Okochi, T. Kaneko, H. Sugimoto, S. Inoue, S. Takeda, and A. Nakao, “ICG pulse spectrophotometry for perioperative liver function in hepatectomy,” J. Surg. Res. 103(1), 109–113 (2002).
[Crossref] [PubMed]

Kang, Y.

Y. Kang, M. Choi, J. Lee, G. Y. Koh, K. Kwon, and C. Choi, “Quantitative Analysis of Peripheral Tissue Perfusion Using Spatiotemporal Molecular Dynamics,” PLoS One 4(1), e4275 (2009).
[Crossref] [PubMed]

Ke, S.

R. Sharma, W. Wang, J. C. Rasmussen, A. Joshi, J. P. Houston, K. E. Adams, A. Cameron, S. Ke, S. Kwon, M. E. Mawad, and E. M. Sevick-Muraca, “Quantitative imaging of lymph function,” Am. J. Physiol. Heart Circ. Physiol. 292(6), H3109–H3118 (2007).
[Crossref] [PubMed]

Kim, P.

Kim, Y.

K. Choe, J. Y. Jang, I. Park, Y. Kim, S. Ahn, D. Y. Park, Y. K. Hong, K. Alitalo, G. Y. Koh, and P. Kim, “Intravital imaging of intestinal lacteals unveils lipid drainage through contractility,” J. Clin. Invest. 125(11), 4042–4052 (2015).
[Crossref] [PubMed]

Kino, G. S.

W. Piyawattanametha, H. Ra, Z. Qiu, S. Friedland, J. T. C. Liu, K. Loewke, G. S. Kino, O. Solgaard, T. D. Wang, M. J. Mandella, and C. H. Contag, “In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract,” J. Biomed. Opt. 17(2), 021102 (2012).
[Crossref] [PubMed]

Kitagawa, H.

K. Kono, M. Takashima, E. Yuba, A. Harada, Y. Hiramatsu, H. Kitagawa, T. Otani, K. Maruyama, and S. Aoshima, “Multifunctional liposomes having target specificity, temperature-triggered release, and near-infrared fluorescence imaging for tumor-specific chemotherapy,” J. Control. Release 216, 69–77 (2015).
[Crossref] [PubMed]

Kittler, H.

H. Skvara, H. Kittler, J. A. Schmid, U. Plut, and C. Jonak, “In vivo fluorescence confocal microscopy: indocyanine green enhances the contrast of epidermal and dermal structures,” J. Biomed. Opt. 16(9), 096010 (2011).
[Crossref] [PubMed]

Kobayashi, N.

T. Iijima, T. Aoyagi, Y. Iwao, J. Masuda, M. Fuse, N. Kobayashi, and H. Sankawa, “Cardiac output and circulating blood volume analysis by pulse dye-densitometry,” J. Clin. Monit. 13(2), 81–89 (1997).
[Crossref] [PubMed]

Koh, G. Y.

K. Choe, J. Y. Jang, I. Park, Y. Kim, S. Ahn, D. Y. Park, Y. K. Hong, K. Alitalo, G. Y. Koh, and P. Kim, “Intravital imaging of intestinal lacteals unveils lipid drainage through contractility,” J. Clin. Invest. 125(11), 4042–4052 (2015).
[Crossref] [PubMed]

Y. Kang, M. Choi, J. Lee, G. Y. Koh, K. Kwon, and C. Choi, “Quantitative Analysis of Peripheral Tissue Perfusion Using Spatiotemporal Molecular Dynamics,” PLoS One 4(1), e4275 (2009).
[Crossref] [PubMed]

Konno, H.

N. Unno, M. Nishiyama, M. Suzuki, N. Yamamoto, K. Inuzuka, D. Sagara, H. Tanaka, and H. Konno, “Quantitative lymph imaging for assessment of lymph function using indocyanine green fluorescence lymphography,” Eur. J. Vasc. Endovasc. Surg. 36(2), 230–236 (2008).
[Crossref] [PubMed]

Kono, K.

K. Kono, M. Takashima, E. Yuba, A. Harada, Y. Hiramatsu, H. Kitagawa, T. Otani, K. Maruyama, and S. Aoshima, “Multifunctional liposomes having target specificity, temperature-triggered release, and near-infrared fluorescence imaging for tumor-specific chemotherapy,” J. Control. Release 216, 69–77 (2015).
[Crossref] [PubMed]

Kreutzberg, G. W.

S. Jung, J. Aliberti, P. Graemmel, M. J. Sunshine, G. W. Kreutzberg, A. Sher, and D. R. Littman, “Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion,” Mol. Cell. Biol. 20(11), 4106–4114 (2000).
[Crossref] [PubMed]

Kuppen, P. J. K.

B. E. Schaafsma, J. S. D. Mieog, M. Hutteman, J. R. van der Vorst, P. J. K. Kuppen, C. W. G. M. Löwik, J. V. Frangioni, C. J. H. van de Velde, and A. L. Vahrmeijer, “The Clinical Use of Indocyanine Green as a near-Infrared Fluorescent Contrast Agent for Image-Guided Oncologic Surgery,” J. Surg. Oncol. 104(3), 323–332 (2011).
[Crossref] [PubMed]

Kwon, K.

Y. Kang, M. Choi, J. Lee, G. Y. Koh, K. Kwon, and C. Choi, “Quantitative Analysis of Peripheral Tissue Perfusion Using Spatiotemporal Molecular Dynamics,” PLoS One 4(1), e4275 (2009).
[Crossref] [PubMed]

Kwon, S.

S. Kwon, G. D. Agollah, G. Wu, W. Chan, and E. M. Sevick-Muraca, “Direct visualization of changes of lymphatic function and drainage pathways in lymph node metastasis of B16F10 melanoma using near-infrared fluorescence imaging,” Biomed. Opt. Express 4(6), 967–977 (2013).
[Crossref] [PubMed]

R. Sharma, W. Wang, J. C. Rasmussen, A. Joshi, J. P. Houston, K. E. Adams, A. Cameron, S. Ke, S. Kwon, M. E. Mawad, and E. M. Sevick-Muraca, “Quantitative imaging of lymph function,” Am. J. Physiol. Heart Circ. Physiol. 292(6), H3109–H3118 (2007).
[Crossref] [PubMed]

Laakso, A.

J. T. Alander, I. Kaartinen, A. Laakso, T. Pätilä, T. Spillmann, V. V. Tuchin, M. Venermo, and P. Välisuo, “A review of indocyanine green fluorescent imaging in surgery,” Int. J. Biomed. Imaging 2012, 940585 (2012).
[Crossref] [PubMed]

Larkin, S.

T. Holmes, A. Invernizzi, S. Larkin, and G. Staurenghi, “Dynamic indocyanine green angiography measurements,” J. Biomed. Opt. 17(11), 116028 (2012).
[Crossref] [PubMed]

Lee, J.

M. Choi, K. Choi, S. W. Ryu, J. Lee, and C. Choi, “Dynamic fluorescence imaging for multiparametric measurement of tumor vasculature,” J. Biomed. Opt. 16(4), 046008 (2011).
[Crossref] [PubMed]

Y. Kang, M. Choi, J. Lee, G. Y. Koh, K. Kwon, and C. Choi, “Quantitative Analysis of Peripheral Tissue Perfusion Using Spatiotemporal Molecular Dynamics,” PLoS One 4(1), e4275 (2009).
[Crossref] [PubMed]

Leenders, P.

B. Janssen, J. Debets, P. Leenders, and J. Smits, “Chronic measurement of cardiac output in conscious mice,” Am. J. Physiol. Regul. Integr. Comp. Physiol. 282(3), R928–R935 (2002).
[Crossref] [PubMed]

Leevy, C. M.

C. M. Leevy, F. Smith, J. Longueville, G. Paumgartner, and M. M. Howard, “Indocyanine green clearance as a test for hepatic function. Evaluation by dichromatic ear densitometry,” JAMA 200(3), 236–240 (1967).
[Crossref] [PubMed]

Leroux, J. C.

S. T. Proulx, P. Luciani, S. Derzsi, M. Rinderknecht, V. Mumprecht, J. C. Leroux, and M. Detmar, “Quantitative Imaging of Lymphatic Function with Liposomal Indocyanine Green,” Cancer Res. 70(18), 7053–7062 (2010).
[Crossref] [PubMed]

Lin, C. P.

I. Veilleux, J. A. Spencer, D. P. Biss, D. Cote, and C. P. Lin, “In vivo cell tracking with video rate multimodality laser scanning microscopy,” IEEE J. Sel. Top. Quantum Electron. 14(1), 10–18 (2008).
[Crossref]

Lindquist, R. L.

R. L. Lindquist, G. Shakhar, D. Dudziak, H. Wardemann, T. Eisenreich, M. L. Dustin, and M. C. Nussenzweig, “Visualizing dendritic cell networks in vivo,” Nat. Immunol. 5(12), 1243–1250 (2004).
[Crossref] [PubMed]

Littman, D. R.

S. Jung, J. Aliberti, P. Graemmel, M. J. Sunshine, G. W. Kreutzberg, A. Sher, and D. R. Littman, “Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion,” Mol. Cell. Biol. 20(11), 4106–4114 (2000).
[Crossref] [PubMed]

Liu, F.

G. Zhang, F. Liu, B. Zhang, Y. He, J. Luo, and J. Bai, “Imaging of pharmacokinetic rates of indocyanine green in mouse liver with a hybrid fluorescence molecular tomography/x-ray computed tomography system,” J. Biomed. Opt. 18(4), 040505 (2013).
[Crossref] [PubMed]

X. Liu, X. L. Guo, F. Liu, Y. Zhang, H. Zhang, G. S. Hu, and J. Bai, “Imaging of Indocyanine Green Perfusion in Mouse Liver With Fluorescence Diffuse Optical Tomography,” IEEE Trans. Biomed. Eng. 58, 2139–2143 (2011).

Liu, H.

F. Yan, H. Wu, H. Liu, Z. Deng, H. Liu, W. Duan, X. Liu, and H. Zheng, “Molecular imaging-guided photothermal/photodynamic therapy against tumor by iRGD-modified indocyanine green nanoparticles,” J. Control. Release 224, 217–228 (2016).
[Crossref] [PubMed]

F. Yan, H. Wu, H. Liu, Z. Deng, H. Liu, W. Duan, X. Liu, and H. Zheng, “Molecular imaging-guided photothermal/photodynamic therapy against tumor by iRGD-modified indocyanine green nanoparticles,” J. Control. Release 224, 217–228 (2016).
[Crossref] [PubMed]

Liu, J. T. C.

W. Piyawattanametha, H. Ra, Z. Qiu, S. Friedland, J. T. C. Liu, K. Loewke, G. S. Kino, O. Solgaard, T. D. Wang, M. J. Mandella, and C. H. Contag, “In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract,” J. Biomed. Opt. 17(2), 021102 (2012).
[Crossref] [PubMed]

Liu, X.

F. Yan, H. Wu, H. Liu, Z. Deng, H. Liu, W. Duan, X. Liu, and H. Zheng, “Molecular imaging-guided photothermal/photodynamic therapy against tumor by iRGD-modified indocyanine green nanoparticles,” J. Control. Release 224, 217–228 (2016).
[Crossref] [PubMed]

X. Liu, X. L. Guo, F. Liu, Y. Zhang, H. Zhang, G. S. Hu, and J. Bai, “Imaging of Indocyanine Green Perfusion in Mouse Liver With Fluorescence Diffuse Optical Tomography,” IEEE Trans. Biomed. Eng. 58, 2139–2143 (2011).

Loewke, K.

W. Piyawattanametha, H. Ra, Z. Qiu, S. Friedland, J. T. C. Liu, K. Loewke, G. S. Kino, O. Solgaard, T. D. Wang, M. J. Mandella, and C. H. Contag, “In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract,” J. Biomed. Opt. 17(2), 021102 (2012).
[Crossref] [PubMed]

Longueville, J.

C. M. Leevy, F. Smith, J. Longueville, G. Paumgartner, and M. M. Howard, “Indocyanine green clearance as a test for hepatic function. Evaluation by dichromatic ear densitometry,” JAMA 200(3), 236–240 (1967).
[Crossref] [PubMed]

Löwik, C. W. G. M.

B. E. Schaafsma, J. S. D. Mieog, M. Hutteman, J. R. van der Vorst, P. J. K. Kuppen, C. W. G. M. Löwik, J. V. Frangioni, C. J. H. van de Velde, and A. L. Vahrmeijer, “The Clinical Use of Indocyanine Green as a near-Infrared Fluorescent Contrast Agent for Image-Guided Oncologic Surgery,” J. Surg. Oncol. 104(3), 323–332 (2011).
[Crossref] [PubMed]

Luciani, P.

S. T. Proulx, P. Luciani, S. Derzsi, M. Rinderknecht, V. Mumprecht, J. C. Leroux, and M. Detmar, “Quantitative Imaging of Lymphatic Function with Liposomal Indocyanine Green,” Cancer Res. 70(18), 7053–7062 (2010).
[Crossref] [PubMed]

Luo, J.

G. Zhang, F. Liu, B. Zhang, Y. He, J. Luo, and J. Bai, “Imaging of pharmacokinetic rates of indocyanine green in mouse liver with a hybrid fluorescence molecular tomography/x-ray computed tomography system,” J. Biomed. Opt. 18(4), 040505 (2013).
[Crossref] [PubMed]

Ma, Y.

C. Zheng, M. Zheng, P. Gong, D. Jia, P. Zhang, B. Shi, Z. Sheng, Y. Ma, and L. Cai, “Indocyanine green-loaded biodegradable tumor targeting nanoprobes for in vitro and in vivo imaging,” Biomaterials 33(22), 5603–5609 (2012).
[Crossref] [PubMed]

Mancini, M. C.

A. M. Smith, M. C. Mancini, and S. Nie, “Bioimaging: Second window for in vivo imaging,” Nat. Nanotechnol. 4(11), 710–711 (2009).
[Crossref] [PubMed]

Mandella, M. J.

W. Piyawattanametha, H. Ra, Z. Qiu, S. Friedland, J. T. C. Liu, K. Loewke, G. S. Kino, O. Solgaard, T. D. Wang, M. J. Mandella, and C. H. Contag, “In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract,” J. Biomed. Opt. 17(2), 021102 (2012).
[Crossref] [PubMed]

Martirosyan, N. L.

N. L. Martirosyan, D. D. Cavalcanti, J. M. Eschbacher, P. M. Delaney, A. C. Scheck, M. G. Abdelwahab, P. Nakaji, R. F. Spetzler, and M. C. Preul, “Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor Laboratory investigation,” J. Neurosurg. 115(6), 1131–1138 (2011).
[Crossref] [PubMed]

Maruyama, K.

K. Kono, M. Takashima, E. Yuba, A. Harada, Y. Hiramatsu, H. Kitagawa, T. Otani, K. Maruyama, and S. Aoshima, “Multifunctional liposomes having target specificity, temperature-triggered release, and near-infrared fluorescence imaging for tumor-specific chemotherapy,” J. Control. Release 216, 69–77 (2015).
[Crossref] [PubMed]

Masuda, J.

T. Iijima, T. Aoyagi, Y. Iwao, J. Masuda, M. Fuse, N. Kobayashi, and H. Sankawa, “Cardiac output and circulating blood volume analysis by pulse dye-densitometry,” J. Clin. Monit. 13(2), 81–89 (1997).
[Crossref] [PubMed]

Mawad, M. E.

R. Sharma, W. Wang, J. C. Rasmussen, A. Joshi, J. P. Houston, K. E. Adams, A. Cameron, S. Ke, S. Kwon, M. E. Mawad, and E. M. Sevick-Muraca, “Quantitative imaging of lymph function,” Am. J. Physiol. Heart Circ. Physiol. 292(6), H3109–H3118 (2007).
[Crossref] [PubMed]

Mayr, M.

C. Holm, M. Mayr, E. Höfter, A. Becker, U. J. Pfeiffer, and W. Mühlbauer, “Intraoperative evaluation of skin-flap viability using laser-induced fluorescence of indocyanine green,” Br. J. Plast. Surg. 55(8), 635–644 (2002).
[Crossref] [PubMed]

McCarty, W. J.

L. Prodanov, R. Jindal, S. S. Bale, M. Hegde, W. J. McCarty, I. Golberg, A. Bhushan, M. L. Yarmush, and O. B. Usta, “Long-term maintenance of a microfluidic 3D human liver sinusoid,” Biotechnol. Bioeng. 113(1), 241–246 (2016).
[Crossref] [PubMed]

Mieog, J. S. D.

B. E. Schaafsma, J. S. D. Mieog, M. Hutteman, J. R. van der Vorst, P. J. K. Kuppen, C. W. G. M. Löwik, J. V. Frangioni, C. J. H. van de Velde, and A. L. Vahrmeijer, “The Clinical Use of Indocyanine Green as a near-Infrared Fluorescent Contrast Agent for Image-Guided Oncologic Surgery,” J. Surg. Oncol. 104(3), 323–332 (2011).
[Crossref] [PubMed]

Mordon, S.

T. Desmettre, J. M. Devoisselle, and S. Mordon, “Fluorescence properties and metabolic features of indocyanine green (ICG) as related to angiography,” Surv. Ophthalmol. 45(1), 15–27 (2000).
[Crossref] [PubMed]

Morscher, S.

A. Taruttis, S. Morscher, N. C. Burton, D. Razansky, and V. Ntziachristos, “Fast Multispectral Optoacoustic Tomography (MSOT) for Dynamic Imaging of Pharmacokinetics and Biodistribution in Multiple Organs,” PLoS One 7(1), e30491 (2012).
[Crossref] [PubMed]

Muhanna, N.

J. Zheng, N. Muhanna, R. De Souza, H. Wada, H. Chan, M. K. Akens, T. Anayama, K. Yasufuku, S. Serra, J. Irish, C. Allen, and D. Jaffray, “A multimodal nano agent for image-guided cancer surgery,” Biomaterials 67, 160–168 (2015).
[Crossref] [PubMed]

Mühlbauer, W.

C. Holm, M. Mayr, E. Höfter, A. Becker, U. J. Pfeiffer, and W. Mühlbauer, “Intraoperative evaluation of skin-flap viability using laser-induced fluorescence of indocyanine green,” Br. J. Plast. Surg. 55(8), 635–644 (2002).
[Crossref] [PubMed]

Mumprecht, V.

S. T. Proulx, P. Luciani, S. Derzsi, M. Rinderknecht, V. Mumprecht, J. C. Leroux, and M. Detmar, “Quantitative Imaging of Lymphatic Function with Liposomal Indocyanine Green,” Cancer Res. 70(18), 7053–7062 (2010).
[Crossref] [PubMed]

Mun, J.

Nakaji, P.

N. L. Martirosyan, D. D. Cavalcanti, J. M. Eschbacher, P. M. Delaney, A. C. Scheck, M. G. Abdelwahab, P. Nakaji, R. F. Spetzler, and M. C. Preul, “Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor Laboratory investigation,” J. Neurosurg. 115(6), 1131–1138 (2011).
[Crossref] [PubMed]

Nakao, A.

O. Okochi, T. Kaneko, H. Sugimoto, S. Inoue, S. Takeda, and A. Nakao, “ICG pulse spectrophotometry for perioperative liver function in hepatectomy,” J. Surg. Res. 103(1), 109–113 (2002).
[Crossref] [PubMed]

Nie, S.

A. M. Smith, M. C. Mancini, and S. Nie, “Bioimaging: Second window for in vivo imaging,” Nat. Nanotechnol. 4(11), 710–711 (2009).
[Crossref] [PubMed]

Nishiyama, M.

N. Unno, M. Nishiyama, M. Suzuki, N. Yamamoto, K. Inuzuka, D. Sagara, H. Tanaka, and H. Konno, “Quantitative lymph imaging for assessment of lymph function using indocyanine green fluorescence lymphography,” Eur. J. Vasc. Endovasc. Surg. 36(2), 230–236 (2008).
[Crossref] [PubMed]

Ntziachristos, V.

A. Taruttis, S. Morscher, N. C. Burton, D. Razansky, and V. Ntziachristos, “Fast Multispectral Optoacoustic Tomography (MSOT) for Dynamic Imaging of Pharmacokinetics and Biodistribution in Multiple Organs,” PLoS One 7(1), e30491 (2012).
[Crossref] [PubMed]

V. Ntziachristos, C. Bremer, and R. Weissleder, “Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging,” Eur. Radiol. 13(1), 195–208 (2003).
[PubMed]

Nussenzweig, M. C.

R. L. Lindquist, G. Shakhar, D. Dudziak, H. Wardemann, T. Eisenreich, M. L. Dustin, and M. C. Nussenzweig, “Visualizing dendritic cell networks in vivo,” Nat. Immunol. 5(12), 1243–1250 (2004).
[Crossref] [PubMed]

Okochi, O.

O. Okochi, T. Kaneko, H. Sugimoto, S. Inoue, S. Takeda, and A. Nakao, “ICG pulse spectrophotometry for perioperative liver function in hepatectomy,” J. Surg. Res. 103(1), 109–113 (2002).
[Crossref] [PubMed]

Otani, T.

K. Kono, M. Takashima, E. Yuba, A. Harada, Y. Hiramatsu, H. Kitagawa, T. Otani, K. Maruyama, and S. Aoshima, “Multifunctional liposomes having target specificity, temperature-triggered release, and near-infrared fluorescence imaging for tumor-specific chemotherapy,” J. Control. Release 216, 69–77 (2015).
[Crossref] [PubMed]

Papahadjopoulos, D.

A. Gabizon and D. Papahadjopoulos, “Liposome Formulations with Prolonged Circulation Time in Blood and Enhanced Uptake by Tumors,” Proc. Natl. Acad. Sci. U.S.A. 85(18), 6949–6953 (1988).
[Crossref] [PubMed]

Park, D. Y.

K. Choe, J. Y. Jang, I. Park, Y. Kim, S. Ahn, D. Y. Park, Y. K. Hong, K. Alitalo, G. Y. Koh, and P. Kim, “Intravital imaging of intestinal lacteals unveils lipid drainage through contractility,” J. Clin. Invest. 125(11), 4042–4052 (2015).
[Crossref] [PubMed]

Park, I.

K. Choe, J. Y. Jang, I. Park, Y. Kim, S. Ahn, D. Y. Park, Y. K. Hong, K. Alitalo, G. Y. Koh, and P. Kim, “Intravital imaging of intestinal lacteals unveils lipid drainage through contractility,” J. Clin. Invest. 125(11), 4042–4052 (2015).
[Crossref] [PubMed]

Pätilä, T.

J. T. Alander, I. Kaartinen, A. Laakso, T. Pätilä, T. Spillmann, V. V. Tuchin, M. Venermo, and P. Välisuo, “A review of indocyanine green fluorescent imaging in surgery,” Int. J. Biomed. Imaging 2012, 940585 (2012).
[Crossref] [PubMed]

Patwardhan, S.

Paumgartner, G.

C. M. Leevy, F. Smith, J. Longueville, G. Paumgartner, and M. M. Howard, “Indocyanine green clearance as a test for hepatic function. Evaluation by dichromatic ear densitometry,” JAMA 200(3), 236–240 (1967).
[Crossref] [PubMed]

Pfeiffer, U. J.

C. Holm, M. Mayr, E. Höfter, A. Becker, U. J. Pfeiffer, and W. Mühlbauer, “Intraoperative evaluation of skin-flap viability using laser-induced fluorescence of indocyanine green,” Br. J. Plast. Surg. 55(8), 635–644 (2002).
[Crossref] [PubMed]

Piyawattanametha, W.

W. Piyawattanametha, H. Ra, Z. Qiu, S. Friedland, J. T. C. Liu, K. Loewke, G. S. Kino, O. Solgaard, T. D. Wang, M. J. Mandella, and C. H. Contag, “In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract,” J. Biomed. Opt. 17(2), 021102 (2012).
[Crossref] [PubMed]

Plut, U.

H. Skvara, H. Kittler, J. A. Schmid, U. Plut, and C. Jonak, “In vivo fluorescence confocal microscopy: indocyanine green enhances the contrast of epidermal and dermal structures,” J. Biomed. Opt. 16(9), 096010 (2011).
[Crossref] [PubMed]

Preul, M. C.

N. L. Martirosyan, D. D. Cavalcanti, J. M. Eschbacher, P. M. Delaney, A. C. Scheck, M. G. Abdelwahab, P. Nakaji, R. F. Spetzler, and M. C. Preul, “Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor Laboratory investigation,” J. Neurosurg. 115(6), 1131–1138 (2011).
[Crossref] [PubMed]

Prodanov, L.

L. Prodanov, R. Jindal, S. S. Bale, M. Hegde, W. J. McCarty, I. Golberg, A. Bhushan, M. L. Yarmush, and O. B. Usta, “Long-term maintenance of a microfluidic 3D human liver sinusoid,” Biotechnol. Bioeng. 113(1), 241–246 (2016).
[Crossref] [PubMed]

Proulx, S. T.

S. T. Proulx, P. Luciani, S. Derzsi, M. Rinderknecht, V. Mumprecht, J. C. Leroux, and M. Detmar, “Quantitative Imaging of Lymphatic Function with Liposomal Indocyanine Green,” Cancer Res. 70(18), 7053–7062 (2010).
[Crossref] [PubMed]

Qiu, X.

A. Yuan, X. Tang, X. Qiu, K. Jiang, J. Wu, and Y. Hu, “Activatable photodynamic destruction of cancer cells by NIR dye/photosensitizer loaded liposomes,” Chem. Commun. (Camb.) 51(16), 3340–3342 (2015).
[Crossref] [PubMed]

Qiu, Z.

W. Piyawattanametha, H. Ra, Z. Qiu, S. Friedland, J. T. C. Liu, K. Loewke, G. S. Kino, O. Solgaard, T. D. Wang, M. J. Mandella, and C. H. Contag, “In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract,” J. Biomed. Opt. 17(2), 021102 (2012).
[Crossref] [PubMed]

Ra, H.

W. Piyawattanametha, H. Ra, Z. Qiu, S. Friedland, J. T. C. Liu, K. Loewke, G. S. Kino, O. Solgaard, T. D. Wang, M. J. Mandella, and C. H. Contag, “In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract,” J. Biomed. Opt. 17(2), 021102 (2012).
[Crossref] [PubMed]

Rajadhyaksha, M.

Rasmussen, J. C.

R. Sharma, W. Wang, J. C. Rasmussen, A. Joshi, J. P. Houston, K. E. Adams, A. Cameron, S. Ke, S. Kwon, M. E. Mawad, and E. M. Sevick-Muraca, “Quantitative imaging of lymph function,” Am. J. Physiol. Heart Circ. Physiol. 292(6), H3109–H3118 (2007).
[Crossref] [PubMed]

Razansky, D.

A. Taruttis, S. Morscher, N. C. Burton, D. Razansky, and V. Ntziachristos, “Fast Multispectral Optoacoustic Tomography (MSOT) for Dynamic Imaging of Pharmacokinetics and Biodistribution in Multiple Organs,” PLoS One 7(1), e30491 (2012).
[Crossref] [PubMed]

Rengan, A. K.

A. K. Rengan, M. Jagtap, A. De, R. Banerjee, and R. Srivastava, “Multifunctional gold coated thermo-sensitive liposomes for multimodal imaging and photo-thermal therapy of breast cancer cells,” Nanoscale 6(2), 916–923 (2014).
[Crossref] [PubMed]

Rinderknecht, M.

S. T. Proulx, P. Luciani, S. Derzsi, M. Rinderknecht, V. Mumprecht, J. C. Leroux, and M. Detmar, “Quantitative Imaging of Lymphatic Function with Liposomal Indocyanine Green,” Cancer Res. 70(18), 7053–7062 (2010).
[Crossref] [PubMed]

Ryan, J. C.

J. C. Ryan, K. W. Dunn, and B. S. Decker, “Effects of chronic kidney disease on liver transport: quantitative intravital microscopy of fluorescein transport in the rat liver,” Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(12), R1488–R1492 (2014).
[Crossref] [PubMed]

Ryu, S. W.

M. Choi, K. Choi, S. W. Ryu, J. Lee, and C. Choi, “Dynamic fluorescence imaging for multiparametric measurement of tumor vasculature,” J. Biomed. Opt. 16(4), 046008 (2011).
[Crossref] [PubMed]

Sagara, D.

N. Unno, M. Nishiyama, M. Suzuki, N. Yamamoto, K. Inuzuka, D. Sagara, H. Tanaka, and H. Konno, “Quantitative lymph imaging for assessment of lymph function using indocyanine green fluorescence lymphography,” Eur. J. Vasc. Endovasc. Surg. 36(2), 230–236 (2008).
[Crossref] [PubMed]

Sankawa, H.

T. Iijima, T. Aoyagi, Y. Iwao, J. Masuda, M. Fuse, N. Kobayashi, and H. Sankawa, “Cardiac output and circulating blood volume analysis by pulse dye-densitometry,” J. Clin. Monit. 13(2), 81–89 (1997).
[Crossref] [PubMed]

Schaafsma, B. E.

B. E. Schaafsma, J. S. D. Mieog, M. Hutteman, J. R. van der Vorst, P. J. K. Kuppen, C. W. G. M. Löwik, J. V. Frangioni, C. J. H. van de Velde, and A. L. Vahrmeijer, “The Clinical Use of Indocyanine Green as a near-Infrared Fluorescent Contrast Agent for Image-Guided Oncologic Surgery,” J. Surg. Oncol. 104(3), 323–332 (2011).
[Crossref] [PubMed]

Scheck, A. C.

N. L. Martirosyan, D. D. Cavalcanti, J. M. Eschbacher, P. M. Delaney, A. C. Scheck, M. G. Abdelwahab, P. Nakaji, R. F. Spetzler, and M. C. Preul, “Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor Laboratory investigation,” J. Neurosurg. 115(6), 1131–1138 (2011).
[Crossref] [PubMed]

Schmid, J. A.

H. Skvara, H. Kittler, J. A. Schmid, U. Plut, and C. Jonak, “In vivo fluorescence confocal microscopy: indocyanine green enhances the contrast of epidermal and dermal structures,” J. Biomed. Opt. 16(9), 096010 (2011).
[Crossref] [PubMed]

Schmitz, C. H.

Seo, H.

Serra, S.

J. Zheng, N. Muhanna, R. De Souza, H. Wada, H. Chan, M. K. Akens, T. Anayama, K. Yasufuku, S. Serra, J. Irish, C. Allen, and D. Jaffray, “A multimodal nano agent for image-guided cancer surgery,” Biomaterials 67, 160–168 (2015).
[Crossref] [PubMed]

Sevick-Muraca, E. M.

S. Kwon, G. D. Agollah, G. Wu, W. Chan, and E. M. Sevick-Muraca, “Direct visualization of changes of lymphatic function and drainage pathways in lymph node metastasis of B16F10 melanoma using near-infrared fluorescence imaging,” Biomed. Opt. Express 4(6), 967–977 (2013).
[Crossref] [PubMed]

R. Sharma, W. Wang, J. C. Rasmussen, A. Joshi, J. P. Houston, K. E. Adams, A. Cameron, S. Ke, S. Kwon, M. E. Mawad, and E. M. Sevick-Muraca, “Quantitative imaging of lymph function,” Am. J. Physiol. Heart Circ. Physiol. 292(6), H3109–H3118 (2007).
[Crossref] [PubMed]

Shakhar, G.

R. L. Lindquist, G. Shakhar, D. Dudziak, H. Wardemann, T. Eisenreich, M. L. Dustin, and M. C. Nussenzweig, “Visualizing dendritic cell networks in vivo,” Nat. Immunol. 5(12), 1243–1250 (2004).
[Crossref] [PubMed]

Sharma, R.

R. Sharma, W. Wang, J. C. Rasmussen, A. Joshi, J. P. Houston, K. E. Adams, A. Cameron, S. Ke, S. Kwon, M. E. Mawad, and E. M. Sevick-Muraca, “Quantitative imaging of lymph function,” Am. J. Physiol. Heart Circ. Physiol. 292(6), H3109–H3118 (2007).
[Crossref] [PubMed]

Sheng, Z.

C. Zheng, M. Zheng, P. Gong, D. Jia, P. Zhang, B. Shi, Z. Sheng, Y. Ma, and L. Cai, “Indocyanine green-loaded biodegradable tumor targeting nanoprobes for in vitro and in vivo imaging,” Biomaterials 33(22), 5603–5609 (2012).
[Crossref] [PubMed]

Sher, A.

S. Jung, J. Aliberti, P. Graemmel, M. J. Sunshine, G. W. Kreutzberg, A. Sher, and D. R. Littman, “Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion,” Mol. Cell. Biol. 20(11), 4106–4114 (2000).
[Crossref] [PubMed]

Shi, B.

C. Zheng, M. Zheng, P. Gong, D. Jia, P. Zhang, B. Shi, Z. Sheng, Y. Ma, and L. Cai, “Indocyanine green-loaded biodegradable tumor targeting nanoprobes for in vitro and in vivo imaging,” Biomaterials 33(22), 5603–5609 (2012).
[Crossref] [PubMed]

Skvara, H.

H. Skvara, H. Kittler, J. A. Schmid, U. Plut, and C. Jonak, “In vivo fluorescence confocal microscopy: indocyanine green enhances the contrast of epidermal and dermal structures,” J. Biomed. Opt. 16(9), 096010 (2011).
[Crossref] [PubMed]

Smith, A. M.

A. M. Smith, M. C. Mancini, and S. Nie, “Bioimaging: Second window for in vivo imaging,” Nat. Nanotechnol. 4(11), 710–711 (2009).
[Crossref] [PubMed]

Smith, F.

C. M. Leevy, F. Smith, J. Longueville, G. Paumgartner, and M. M. Howard, “Indocyanine green clearance as a test for hepatic function. Evaluation by dichromatic ear densitometry,” JAMA 200(3), 236–240 (1967).
[Crossref] [PubMed]

Smits, J.

B. Janssen, J. Debets, P. Leenders, and J. Smits, “Chronic measurement of cardiac output in conscious mice,” Am. J. Physiol. Regul. Integr. Comp. Physiol. 282(3), R928–R935 (2002).
[Crossref] [PubMed]

Solgaard, O.

W. Piyawattanametha, H. Ra, Z. Qiu, S. Friedland, J. T. C. Liu, K. Loewke, G. S. Kino, O. Solgaard, T. D. Wang, M. J. Mandella, and C. H. Contag, “In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract,” J. Biomed. Opt. 17(2), 021102 (2012).
[Crossref] [PubMed]

Song, E.

Song, W. T.

W. T. Song, Z. H. Tang, D. W. Zhang, N. Burton, W. Driessen, and X. S. Chen, “Comprehensive studies of pharmacokinetics and biodistribution of indocyanine green and liposomal indocyanine green by multispectral optoacoustic tomography,” Rsc Adv 5(5), 3807–3813 (2015).
[Crossref]

Spencer, J. A.

I. Veilleux, J. A. Spencer, D. P. Biss, D. Cote, and C. P. Lin, “In vivo cell tracking with video rate multimodality laser scanning microscopy,” IEEE J. Sel. Top. Quantum Electron. 14(1), 10–18 (2008).
[Crossref]

Spetzler, R. F.

N. L. Martirosyan, D. D. Cavalcanti, J. M. Eschbacher, P. M. Delaney, A. C. Scheck, M. G. Abdelwahab, P. Nakaji, R. F. Spetzler, and M. C. Preul, “Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor Laboratory investigation,” J. Neurosurg. 115(6), 1131–1138 (2011).
[Crossref] [PubMed]

Spillmann, T.

J. T. Alander, I. Kaartinen, A. Laakso, T. Pätilä, T. Spillmann, V. V. Tuchin, M. Venermo, and P. Välisuo, “A review of indocyanine green fluorescent imaging in surgery,” Int. J. Biomed. Imaging 2012, 940585 (2012).
[Crossref] [PubMed]

Srivastava, R.

A. K. Rengan, M. Jagtap, A. De, R. Banerjee, and R. Srivastava, “Multifunctional gold coated thermo-sensitive liposomes for multimodal imaging and photo-thermal therapy of breast cancer cells,” Nanoscale 6(2), 916–923 (2014).
[Crossref] [PubMed]

Staurenghi, G.

T. Holmes, A. Invernizzi, S. Larkin, and G. Staurenghi, “Dynamic indocyanine green angiography measurements,” J. Biomed. Opt. 17(11), 116028 (2012).
[Crossref] [PubMed]

Steinbrink, J.

Sugimoto, H.

O. Okochi, T. Kaneko, H. Sugimoto, S. Inoue, S. Takeda, and A. Nakao, “ICG pulse spectrophotometry for perioperative liver function in hepatectomy,” J. Surg. Res. 103(1), 109–113 (2002).
[Crossref] [PubMed]

Sunshine, M. J.

S. Jung, J. Aliberti, P. Graemmel, M. J. Sunshine, G. W. Kreutzberg, A. Sher, and D. R. Littman, “Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion,” Mol. Cell. Biol. 20(11), 4106–4114 (2000).
[Crossref] [PubMed]

Suzuki, M.

N. Unno, M. Nishiyama, M. Suzuki, N. Yamamoto, K. Inuzuka, D. Sagara, H. Tanaka, and H. Konno, “Quantitative lymph imaging for assessment of lymph function using indocyanine green fluorescence lymphography,” Eur. J. Vasc. Endovasc. Surg. 36(2), 230–236 (2008).
[Crossref] [PubMed]

Tacke, F.

F. Heymann and F. Tacke, “Immunology in the liver--from homeostasis to disease,” Nat. Rev. Gastroenterol. Hepatol. 13(2), 88–110 (2016).
[Crossref] [PubMed]

Takashima, M.

K. Kono, M. Takashima, E. Yuba, A. Harada, Y. Hiramatsu, H. Kitagawa, T. Otani, K. Maruyama, and S. Aoshima, “Multifunctional liposomes having target specificity, temperature-triggered release, and near-infrared fluorescence imaging for tumor-specific chemotherapy,” J. Control. Release 216, 69–77 (2015).
[Crossref] [PubMed]

Takeda, S.

O. Okochi, T. Kaneko, H. Sugimoto, S. Inoue, S. Takeda, and A. Nakao, “ICG pulse spectrophotometry for perioperative liver function in hepatectomy,” J. Surg. Res. 103(1), 109–113 (2002).
[Crossref] [PubMed]

Tanaka, H.

N. Unno, M. Nishiyama, M. Suzuki, N. Yamamoto, K. Inuzuka, D. Sagara, H. Tanaka, and H. Konno, “Quantitative lymph imaging for assessment of lymph function using indocyanine green fluorescence lymphography,” Eur. J. Vasc. Endovasc. Surg. 36(2), 230–236 (2008).
[Crossref] [PubMed]

Tang, X.

A. Yuan, X. Tang, X. Qiu, K. Jiang, J. Wu, and Y. Hu, “Activatable photodynamic destruction of cancer cells by NIR dye/photosensitizer loaded liposomes,” Chem. Commun. (Camb.) 51(16), 3340–3342 (2015).
[Crossref] [PubMed]

Tang, Z. H.

W. T. Song, Z. H. Tang, D. W. Zhang, N. Burton, W. Driessen, and X. S. Chen, “Comprehensive studies of pharmacokinetics and biodistribution of indocyanine green and liposomal indocyanine green by multispectral optoacoustic tomography,” Rsc Adv 5(5), 3807–3813 (2015).
[Crossref]

Taruttis, A.

A. Taruttis, S. Morscher, N. C. Burton, D. Razansky, and V. Ntziachristos, “Fast Multispectral Optoacoustic Tomography (MSOT) for Dynamic Imaging of Pharmacokinetics and Biodistribution in Multiple Organs,” PLoS One 7(1), e30491 (2012).
[Crossref] [PubMed]

Tuchin, V. V.

J. T. Alander, I. Kaartinen, A. Laakso, T. Pätilä, T. Spillmann, V. V. Tuchin, M. Venermo, and P. Välisuo, “A review of indocyanine green fluorescent imaging in surgery,” Int. J. Biomed. Imaging 2012, 940585 (2012).
[Crossref] [PubMed]

Unno, N.

N. Unno, M. Nishiyama, M. Suzuki, N. Yamamoto, K. Inuzuka, D. Sagara, H. Tanaka, and H. Konno, “Quantitative lymph imaging for assessment of lymph function using indocyanine green fluorescence lymphography,” Eur. J. Vasc. Endovasc. Surg. 36(2), 230–236 (2008).
[Crossref] [PubMed]

Usta, O. B.

L. Prodanov, R. Jindal, S. S. Bale, M. Hegde, W. J. McCarty, I. Golberg, A. Bhushan, M. L. Yarmush, and O. B. Usta, “Long-term maintenance of a microfluidic 3D human liver sinusoid,” Biotechnol. Bioeng. 113(1), 241–246 (2016).
[Crossref] [PubMed]

Vahrmeijer, A. L.

B. E. Schaafsma, J. S. D. Mieog, M. Hutteman, J. R. van der Vorst, P. J. K. Kuppen, C. W. G. M. Löwik, J. V. Frangioni, C. J. H. van de Velde, and A. L. Vahrmeijer, “The Clinical Use of Indocyanine Green as a near-Infrared Fluorescent Contrast Agent for Image-Guided Oncologic Surgery,” J. Surg. Oncol. 104(3), 323–332 (2011).
[Crossref] [PubMed]

Välisuo, P.

J. T. Alander, I. Kaartinen, A. Laakso, T. Pätilä, T. Spillmann, V. V. Tuchin, M. Venermo, and P. Välisuo, “A review of indocyanine green fluorescent imaging in surgery,” Int. J. Biomed. Imaging 2012, 940585 (2012).
[Crossref] [PubMed]

van de Velde, C. J. H.

B. E. Schaafsma, J. S. D. Mieog, M. Hutteman, J. R. van der Vorst, P. J. K. Kuppen, C. W. G. M. Löwik, J. V. Frangioni, C. J. H. van de Velde, and A. L. Vahrmeijer, “The Clinical Use of Indocyanine Green as a near-Infrared Fluorescent Contrast Agent for Image-Guided Oncologic Surgery,” J. Surg. Oncol. 104(3), 323–332 (2011).
[Crossref] [PubMed]

van der Vorst, J. R.

B. E. Schaafsma, J. S. D. Mieog, M. Hutteman, J. R. van der Vorst, P. J. K. Kuppen, C. W. G. M. Löwik, J. V. Frangioni, C. J. H. van de Velde, and A. L. Vahrmeijer, “The Clinical Use of Indocyanine Green as a near-Infrared Fluorescent Contrast Agent for Image-Guided Oncologic Surgery,” J. Surg. Oncol. 104(3), 323–332 (2011).
[Crossref] [PubMed]

Veilleux, I.

I. Veilleux, J. A. Spencer, D. P. Biss, D. Cote, and C. P. Lin, “In vivo cell tracking with video rate multimodality laser scanning microscopy,” IEEE J. Sel. Top. Quantum Electron. 14(1), 10–18 (2008).
[Crossref]

Venermo, M.

J. T. Alander, I. Kaartinen, A. Laakso, T. Pätilä, T. Spillmann, V. V. Tuchin, M. Venermo, and P. Välisuo, “A review of indocyanine green fluorescent imaging in surgery,” Int. J. Biomed. Imaging 2012, 940585 (2012).
[Crossref] [PubMed]

Vinokurov, N. A.

Wada, H.

J. Zheng, N. Muhanna, R. De Souza, H. Wada, H. Chan, M. K. Akens, T. Anayama, K. Yasufuku, S. Serra, J. Irish, C. Allen, and D. Jaffray, “A multimodal nano agent for image-guided cancer surgery,” Biomaterials 67, 160–168 (2015).
[Crossref] [PubMed]

Wang, T. D.

W. Piyawattanametha, H. Ra, Z. Qiu, S. Friedland, J. T. C. Liu, K. Loewke, G. S. Kino, O. Solgaard, T. D. Wang, M. J. Mandella, and C. H. Contag, “In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract,” J. Biomed. Opt. 17(2), 021102 (2012).
[Crossref] [PubMed]

Wang, W.

R. Sharma, W. Wang, J. C. Rasmussen, A. Joshi, J. P. Houston, K. E. Adams, A. Cameron, S. Ke, S. Kwon, M. E. Mawad, and E. M. Sevick-Muraca, “Quantitative imaging of lymph function,” Am. J. Physiol. Heart Circ. Physiol. 292(6), H3109–H3118 (2007).
[Crossref] [PubMed]

Wardemann, H.

R. L. Lindquist, G. Shakhar, D. Dudziak, H. Wardemann, T. Eisenreich, M. L. Dustin, and M. C. Nussenzweig, “Visualizing dendritic cell networks in vivo,” Nat. Immunol. 5(12), 1243–1250 (2004).
[Crossref] [PubMed]

Webb, R. H.

Weissleder, R.

V. Ntziachristos, C. Bremer, and R. Weissleder, “Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging,” Eur. Radiol. 13(1), 195–208 (2003).
[PubMed]

R. Weissleder, “A clearer vision for in vivo imaging,” Nat. Biotechnol. 19(4), 316–317 (2001).
[Crossref] [PubMed]

Wu, G.

Wu, H.

F. Yan, H. Wu, H. Liu, Z. Deng, H. Liu, W. Duan, X. Liu, and H. Zheng, “Molecular imaging-guided photothermal/photodynamic therapy against tumor by iRGD-modified indocyanine green nanoparticles,” J. Control. Release 224, 217–228 (2016).
[Crossref] [PubMed]

Wu, J.

A. Yuan, X. Tang, X. Qiu, K. Jiang, J. Wu, and Y. Hu, “Activatable photodynamic destruction of cancer cells by NIR dye/photosensitizer loaded liposomes,” Chem. Commun. (Camb.) 51(16), 3340–3342 (2015).
[Crossref] [PubMed]

Yamamoto, N.

N. Unno, M. Nishiyama, M. Suzuki, N. Yamamoto, K. Inuzuka, D. Sagara, H. Tanaka, and H. Konno, “Quantitative lymph imaging for assessment of lymph function using indocyanine green fluorescence lymphography,” Eur. J. Vasc. Endovasc. Surg. 36(2), 230–236 (2008).
[Crossref] [PubMed]

Yan, F.

F. Yan, H. Wu, H. Liu, Z. Deng, H. Liu, W. Duan, X. Liu, and H. Zheng, “Molecular imaging-guided photothermal/photodynamic therapy against tumor by iRGD-modified indocyanine green nanoparticles,” J. Control. Release 224, 217–228 (2016).
[Crossref] [PubMed]

Yarmush, M. L.

L. Prodanov, R. Jindal, S. S. Bale, M. Hegde, W. J. McCarty, I. Golberg, A. Bhushan, M. L. Yarmush, and O. B. Usta, “Long-term maintenance of a microfluidic 3D human liver sinusoid,” Biotechnol. Bioeng. 113(1), 241–246 (2016).
[Crossref] [PubMed]

Yasufuku, K.

J. Zheng, N. Muhanna, R. De Souza, H. Wada, H. Chan, M. K. Akens, T. Anayama, K. Yasufuku, S. Serra, J. Irish, C. Allen, and D. Jaffray, “A multimodal nano agent for image-guided cancer surgery,” Biomaterials 67, 160–168 (2015).
[Crossref] [PubMed]

Yuan, A.

A. Yuan, X. Tang, X. Qiu, K. Jiang, J. Wu, and Y. Hu, “Activatable photodynamic destruction of cancer cells by NIR dye/photosensitizer loaded liposomes,” Chem. Commun. (Camb.) 51(16), 3340–3342 (2015).
[Crossref] [PubMed]

Yuba, E.

K. Kono, M. Takashima, E. Yuba, A. Harada, Y. Hiramatsu, H. Kitagawa, T. Otani, K. Maruyama, and S. Aoshima, “Multifunctional liposomes having target specificity, temperature-triggered release, and near-infrared fluorescence imaging for tumor-specific chemotherapy,” J. Control. Release 216, 69–77 (2015).
[Crossref] [PubMed]

Zhang, B.

G. Zhang, F. Liu, B. Zhang, Y. He, J. Luo, and J. Bai, “Imaging of pharmacokinetic rates of indocyanine green in mouse liver with a hybrid fluorescence molecular tomography/x-ray computed tomography system,” J. Biomed. Opt. 18(4), 040505 (2013).
[Crossref] [PubMed]

Zhang, D. W.

W. T. Song, Z. H. Tang, D. W. Zhang, N. Burton, W. Driessen, and X. S. Chen, “Comprehensive studies of pharmacokinetics and biodistribution of indocyanine green and liposomal indocyanine green by multispectral optoacoustic tomography,” Rsc Adv 5(5), 3807–3813 (2015).
[Crossref]

Zhang, G.

G. Zhang, F. Liu, B. Zhang, Y. He, J. Luo, and J. Bai, “Imaging of pharmacokinetic rates of indocyanine green in mouse liver with a hybrid fluorescence molecular tomography/x-ray computed tomography system,” J. Biomed. Opt. 18(4), 040505 (2013).
[Crossref] [PubMed]

Zhang, H.

X. Liu, X. L. Guo, F. Liu, Y. Zhang, H. Zhang, G. S. Hu, and J. Bai, “Imaging of Indocyanine Green Perfusion in Mouse Liver With Fluorescence Diffuse Optical Tomography,” IEEE Trans. Biomed. Eng. 58, 2139–2143 (2011).

Zhang, P.

C. Zheng, M. Zheng, P. Gong, D. Jia, P. Zhang, B. Shi, Z. Sheng, Y. Ma, and L. Cai, “Indocyanine green-loaded biodegradable tumor targeting nanoprobes for in vitro and in vivo imaging,” Biomaterials 33(22), 5603–5609 (2012).
[Crossref] [PubMed]

Zhang, Y.

X. Liu, X. L. Guo, F. Liu, Y. Zhang, H. Zhang, G. S. Hu, and J. Bai, “Imaging of Indocyanine Green Perfusion in Mouse Liver With Fluorescence Diffuse Optical Tomography,” IEEE Trans. Biomed. Eng. 58, 2139–2143 (2011).

Zheng, C.

C. Zheng, M. Zheng, P. Gong, D. Jia, P. Zhang, B. Shi, Z. Sheng, Y. Ma, and L. Cai, “Indocyanine green-loaded biodegradable tumor targeting nanoprobes for in vitro and in vivo imaging,” Biomaterials 33(22), 5603–5609 (2012).
[Crossref] [PubMed]

Zheng, H.

F. Yan, H. Wu, H. Liu, Z. Deng, H. Liu, W. Duan, X. Liu, and H. Zheng, “Molecular imaging-guided photothermal/photodynamic therapy against tumor by iRGD-modified indocyanine green nanoparticles,” J. Control. Release 224, 217–228 (2016).
[Crossref] [PubMed]

Zheng, J.

J. Zheng, N. Muhanna, R. De Souza, H. Wada, H. Chan, M. K. Akens, T. Anayama, K. Yasufuku, S. Serra, J. Irish, C. Allen, and D. Jaffray, “A multimodal nano agent for image-guided cancer surgery,” Biomaterials 67, 160–168 (2015).
[Crossref] [PubMed]

Zheng, M.

C. Zheng, M. Zheng, P. Gong, D. Jia, P. Zhang, B. Shi, Z. Sheng, Y. Ma, and L. Cai, “Indocyanine green-loaded biodegradable tumor targeting nanoprobes for in vitro and in vivo imaging,” Biomaterials 33(22), 5603–5609 (2012).
[Crossref] [PubMed]

Am. J. Physiol. Heart Circ. Physiol. (1)

R. Sharma, W. Wang, J. C. Rasmussen, A. Joshi, J. P. Houston, K. E. Adams, A. Cameron, S. Ke, S. Kwon, M. E. Mawad, and E. M. Sevick-Muraca, “Quantitative imaging of lymph function,” Am. J. Physiol. Heart Circ. Physiol. 292(6), H3109–H3118 (2007).
[Crossref] [PubMed]

Am. J. Physiol. Regul. Integr. Comp. Physiol. (2)

B. Janssen, J. Debets, P. Leenders, and J. Smits, “Chronic measurement of cardiac output in conscious mice,” Am. J. Physiol. Regul. Integr. Comp. Physiol. 282(3), R928–R935 (2002).
[Crossref] [PubMed]

J. C. Ryan, K. W. Dunn, and B. S. Decker, “Effects of chronic kidney disease on liver transport: quantitative intravital microscopy of fluorescein transport in the rat liver,” Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(12), R1488–R1492 (2014).
[Crossref] [PubMed]

Appl. Opt. (1)

Biomaterials (2)

C. Zheng, M. Zheng, P. Gong, D. Jia, P. Zhang, B. Shi, Z. Sheng, Y. Ma, and L. Cai, “Indocyanine green-loaded biodegradable tumor targeting nanoprobes for in vitro and in vivo imaging,” Biomaterials 33(22), 5603–5609 (2012).
[Crossref] [PubMed]

J. Zheng, N. Muhanna, R. De Souza, H. Wada, H. Chan, M. K. Akens, T. Anayama, K. Yasufuku, S. Serra, J. Irish, C. Allen, and D. Jaffray, “A multimodal nano agent for image-guided cancer surgery,” Biomaterials 67, 160–168 (2015).
[Crossref] [PubMed]

Biomed. Opt. Express (3)

Biotechnol. Bioeng. (1)

L. Prodanov, R. Jindal, S. S. Bale, M. Hegde, W. J. McCarty, I. Golberg, A. Bhushan, M. L. Yarmush, and O. B. Usta, “Long-term maintenance of a microfluidic 3D human liver sinusoid,” Biotechnol. Bioeng. 113(1), 241–246 (2016).
[Crossref] [PubMed]

Br. J. Plast. Surg. (1)

C. Holm, M. Mayr, E. Höfter, A. Becker, U. J. Pfeiffer, and W. Mühlbauer, “Intraoperative evaluation of skin-flap viability using laser-induced fluorescence of indocyanine green,” Br. J. Plast. Surg. 55(8), 635–644 (2002).
[Crossref] [PubMed]

Cancer Res. (1)

S. T. Proulx, P. Luciani, S. Derzsi, M. Rinderknecht, V. Mumprecht, J. C. Leroux, and M. Detmar, “Quantitative Imaging of Lymphatic Function with Liposomal Indocyanine Green,” Cancer Res. 70(18), 7053–7062 (2010).
[Crossref] [PubMed]

Chem. Commun. (Camb.) (1)

A. Yuan, X. Tang, X. Qiu, K. Jiang, J. Wu, and Y. Hu, “Activatable photodynamic destruction of cancer cells by NIR dye/photosensitizer loaded liposomes,” Chem. Commun. (Camb.) 51(16), 3340–3342 (2015).
[Crossref] [PubMed]

Curr. Opin. Chem. Biol. (1)

J. V. Frangioni, “In vivo near-infrared fluorescence imaging,” Curr. Opin. Chem. Biol. 7(5), 626–634 (2003).
[Crossref] [PubMed]

Eur. J. Vasc. Endovasc. Surg. (1)

N. Unno, M. Nishiyama, M. Suzuki, N. Yamamoto, K. Inuzuka, D. Sagara, H. Tanaka, and H. Konno, “Quantitative lymph imaging for assessment of lymph function using indocyanine green fluorescence lymphography,” Eur. J. Vasc. Endovasc. Surg. 36(2), 230–236 (2008).
[Crossref] [PubMed]

Eur. Radiol. (1)

V. Ntziachristos, C. Bremer, and R. Weissleder, “Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging,” Eur. Radiol. 13(1), 195–208 (2003).
[PubMed]

IEEE J. Sel. Top. Quantum Electron. (1)

I. Veilleux, J. A. Spencer, D. P. Biss, D. Cote, and C. P. Lin, “In vivo cell tracking with video rate multimodality laser scanning microscopy,” IEEE J. Sel. Top. Quantum Electron. 14(1), 10–18 (2008).
[Crossref]

IEEE Trans. Biomed. Eng. (1)

X. Liu, X. L. Guo, F. Liu, Y. Zhang, H. Zhang, G. S. Hu, and J. Bai, “Imaging of Indocyanine Green Perfusion in Mouse Liver With Fluorescence Diffuse Optical Tomography,” IEEE Trans. Biomed. Eng. 58, 2139–2143 (2011).

Int. J. Biomed. Imaging (1)

J. T. Alander, I. Kaartinen, A. Laakso, T. Pätilä, T. Spillmann, V. V. Tuchin, M. Venermo, and P. Välisuo, “A review of indocyanine green fluorescent imaging in surgery,” Int. J. Biomed. Imaging 2012, 940585 (2012).
[Crossref] [PubMed]

J. Biomed. Opt. (5)

G. Zhang, F. Liu, B. Zhang, Y. He, J. Luo, and J. Bai, “Imaging of pharmacokinetic rates of indocyanine green in mouse liver with a hybrid fluorescence molecular tomography/x-ray computed tomography system,” J. Biomed. Opt. 18(4), 040505 (2013).
[Crossref] [PubMed]

T. Holmes, A. Invernizzi, S. Larkin, and G. Staurenghi, “Dynamic indocyanine green angiography measurements,” J. Biomed. Opt. 17(11), 116028 (2012).
[Crossref] [PubMed]

M. Choi, K. Choi, S. W. Ryu, J. Lee, and C. Choi, “Dynamic fluorescence imaging for multiparametric measurement of tumor vasculature,” J. Biomed. Opt. 16(4), 046008 (2011).
[Crossref] [PubMed]

W. Piyawattanametha, H. Ra, Z. Qiu, S. Friedland, J. T. C. Liu, K. Loewke, G. S. Kino, O. Solgaard, T. D. Wang, M. J. Mandella, and C. H. Contag, “In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract,” J. Biomed. Opt. 17(2), 021102 (2012).
[Crossref] [PubMed]

H. Skvara, H. Kittler, J. A. Schmid, U. Plut, and C. Jonak, “In vivo fluorescence confocal microscopy: indocyanine green enhances the contrast of epidermal and dermal structures,” J. Biomed. Opt. 16(9), 096010 (2011).
[Crossref] [PubMed]

J. Clin. Invest. (1)

K. Choe, J. Y. Jang, I. Park, Y. Kim, S. Ahn, D. Y. Park, Y. K. Hong, K. Alitalo, G. Y. Koh, and P. Kim, “Intravital imaging of intestinal lacteals unveils lipid drainage through contractility,” J. Clin. Invest. 125(11), 4042–4052 (2015).
[Crossref] [PubMed]

J. Clin. Monit. (1)

T. Iijima, T. Aoyagi, Y. Iwao, J. Masuda, M. Fuse, N. Kobayashi, and H. Sankawa, “Cardiac output and circulating blood volume analysis by pulse dye-densitometry,” J. Clin. Monit. 13(2), 81–89 (1997).
[Crossref] [PubMed]

J. Control. Release (2)

K. Kono, M. Takashima, E. Yuba, A. Harada, Y. Hiramatsu, H. Kitagawa, T. Otani, K. Maruyama, and S. Aoshima, “Multifunctional liposomes having target specificity, temperature-triggered release, and near-infrared fluorescence imaging for tumor-specific chemotherapy,” J. Control. Release 216, 69–77 (2015).
[Crossref] [PubMed]

F. Yan, H. Wu, H. Liu, Z. Deng, H. Liu, W. Duan, X. Liu, and H. Zheng, “Molecular imaging-guided photothermal/photodynamic therapy against tumor by iRGD-modified indocyanine green nanoparticles,” J. Control. Release 224, 217–228 (2016).
[Crossref] [PubMed]

J. Neurosurg. (1)

N. L. Martirosyan, D. D. Cavalcanti, J. M. Eschbacher, P. M. Delaney, A. C. Scheck, M. G. Abdelwahab, P. Nakaji, R. F. Spetzler, and M. C. Preul, “Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor Laboratory investigation,” J. Neurosurg. 115(6), 1131–1138 (2011).
[Crossref] [PubMed]

J. Surg. Oncol. (1)

B. E. Schaafsma, J. S. D. Mieog, M. Hutteman, J. R. van der Vorst, P. J. K. Kuppen, C. W. G. M. Löwik, J. V. Frangioni, C. J. H. van de Velde, and A. L. Vahrmeijer, “The Clinical Use of Indocyanine Green as a near-Infrared Fluorescent Contrast Agent for Image-Guided Oncologic Surgery,” J. Surg. Oncol. 104(3), 323–332 (2011).
[Crossref] [PubMed]

J. Surg. Res. (1)

O. Okochi, T. Kaneko, H. Sugimoto, S. Inoue, S. Takeda, and A. Nakao, “ICG pulse spectrophotometry for perioperative liver function in hepatectomy,” J. Surg. Res. 103(1), 109–113 (2002).
[Crossref] [PubMed]

JAMA (1)

C. M. Leevy, F. Smith, J. Longueville, G. Paumgartner, and M. M. Howard, “Indocyanine green clearance as a test for hepatic function. Evaluation by dichromatic ear densitometry,” JAMA 200(3), 236–240 (1967).
[Crossref] [PubMed]

Mol. Cell. Biol. (1)

S. Jung, J. Aliberti, P. Graemmel, M. J. Sunshine, G. W. Kreutzberg, A. Sher, and D. R. Littman, “Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion,” Mol. Cell. Biol. 20(11), 4106–4114 (2000).
[Crossref] [PubMed]

Nanoscale (1)

A. K. Rengan, M. Jagtap, A. De, R. Banerjee, and R. Srivastava, “Multifunctional gold coated thermo-sensitive liposomes for multimodal imaging and photo-thermal therapy of breast cancer cells,” Nanoscale 6(2), 916–923 (2014).
[Crossref] [PubMed]

Nat. Biotechnol. (1)

R. Weissleder, “A clearer vision for in vivo imaging,” Nat. Biotechnol. 19(4), 316–317 (2001).
[Crossref] [PubMed]

Nat. Immunol. (1)

R. L. Lindquist, G. Shakhar, D. Dudziak, H. Wardemann, T. Eisenreich, M. L. Dustin, and M. C. Nussenzweig, “Visualizing dendritic cell networks in vivo,” Nat. Immunol. 5(12), 1243–1250 (2004).
[Crossref] [PubMed]

Nat. Nanotechnol. (1)

A. M. Smith, M. C. Mancini, and S. Nie, “Bioimaging: Second window for in vivo imaging,” Nat. Nanotechnol. 4(11), 710–711 (2009).
[Crossref] [PubMed]

Nat. Rev. Gastroenterol. Hepatol. (1)

F. Heymann and F. Tacke, “Immunology in the liver--from homeostasis to disease,” Nat. Rev. Gastroenterol. Hepatol. 13(2), 88–110 (2016).
[Crossref] [PubMed]

Opt. Express (3)

PLoS One (2)

A. Taruttis, S. Morscher, N. C. Burton, D. Razansky, and V. Ntziachristos, “Fast Multispectral Optoacoustic Tomography (MSOT) for Dynamic Imaging of Pharmacokinetics and Biodistribution in Multiple Organs,” PLoS One 7(1), e30491 (2012).
[Crossref] [PubMed]

Y. Kang, M. Choi, J. Lee, G. Y. Koh, K. Kwon, and C. Choi, “Quantitative Analysis of Peripheral Tissue Perfusion Using Spatiotemporal Molecular Dynamics,” PLoS One 4(1), e4275 (2009).
[Crossref] [PubMed]

Proc. Natl. Acad. Sci. U.S.A. (1)

A. Gabizon and D. Papahadjopoulos, “Liposome Formulations with Prolonged Circulation Time in Blood and Enhanced Uptake by Tumors,” Proc. Natl. Acad. Sci. U.S.A. 85(18), 6949–6953 (1988).
[Crossref] [PubMed]

Rsc Adv (1)

W. T. Song, Z. H. Tang, D. W. Zhang, N. Burton, W. Driessen, and X. S. Chen, “Comprehensive studies of pharmacokinetics and biodistribution of indocyanine green and liposomal indocyanine green by multispectral optoacoustic tomography,” Rsc Adv 5(5), 3807–3813 (2015).
[Crossref]

Surv. Ophthalmol. (1)

T. Desmettre, J. M. Devoisselle, and S. Mordon, “Fluorescence properties and metabolic features of indocyanine green (ICG) as related to angiography,” Surv. Ophthalmol. 45(1), 15–27 (2000).
[Crossref] [PubMed]

Supplementary Material (6)

NameDescription
» Visualization 1       In vivo real-time visualization of intravenously injected free-from ICG in blood circulation at skin
» Visualization 2       In vivo real-time visualization of intravenously injected liposomal ICG in blood circulation at skin
» Visualization 3       In vivo real-time visualization of intravenously injected free-from ICG in liver
» Visualization 4       In vivo real-time visualization of intravenously injected liposomal ICG in liver
» Visualization 5       In vivo real-time visualization of intravenously injected free-form ICG in liver (Magnified View)
» Visualization 6       In vivo real-time visualization of intravenously injected liposomal ICG in liver (Magnified View)

Cited By

OSA participates in Crossref's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (3)

Fig. 1
Fig. 1 (a) Schematic of laser-scanning confocal microscopy: DBS, dichroic beam splitter; BPF, band pass filter; ND, neutral density filter; M, mirror; PMT, photomultiplier tube. Photograph shows an anesthetized live mouse prepared for ear skin imaging, in vivo. (b, c) The representative images acquired at the ear skin of mouse after the intravenous injection of ICG. (b) At immediately after the ICG injection, blood vessels were visible. The artery (arrow) and vein (arrow head) were distinguishable by the vessel diameter and blood flow speed. (c) At 30 minutes after the ICG injection, the lymphatic vessel (arrow head) draining ICG leaked from the blood vessel to dermal tissue was visible. The hair follicle (asterisk) was also distinguishable. Scale bar: 100 μm.
Fig. 2
Fig. 2 (a) Representative sequential images of the peripheral blood vessel in the ear skin of the mouse intravenously administered free-form and liposomal ICG, respectively (Visualization 1 and Visualization 2). Artery and vein are pseudo-colored in red and blue, respectively. (b) The real-time changes of the ICG fluorescence signal in peripheral blood vessel in the ear skin after the intravenous administration of free-form ICG and liposomal ICG. Scale bar: 250 μm.
Fig. 3
Fig. 3 (a) Representative sequential images of the liver of the mouse after intravenous injection of free-form or liposomal ICG, (Visualization 3 and Visualization 4). (b) Magnified sequential images at the area marked by yellow square in (a), (Visualization 5 and Visualization 6). (c, d) Relative fluorescence intensity in (c) liver sinusoid and (d) hepatocyte. (e) Images obtained at the liver at 12 hours after the intravenous injection of free-form and liposomal ICG. No fluorescence signal was observed in the liver of mouse received the free-form ICG injection. In the liver of mouse received liposomal ICG injection, fluorescence signal was observed in sinusoid (arrow) and Kupffer cell (arrowhead). (f) Images obtained at the liver of CD11c-YFP and CX3CR1-GFP mouse at 24 hours after intravenous injection of liposomal ICG. Scale bar: (a) 100 μm, (b, e-f), 25 μm.

Metrics