Abstract

Morphological assessments are used to select embryos with the highest implantation potential, however it is still very limited. The development of new technologies, such as Raman spectroscopy have improved quantitative and qualitative analysis, and consequently led to a better characterization of embryos and improvements on the prediction of their potential. Therefore, we propose a method based on the conventional in vitro culture system of bovine embryos, and the subsequent analysis of the culture media drops by Raman spectroscopy. Our results obtained by PCA analysis clearly showed a separation of the spectral profiles from culture media drops with and without embryos.

© 2015 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Speckle variance OCT for depth resolved assessment of the viability of bovine embryos

S. Caujolle, R. Cernat, G. Silvestri, M. J. Marques, A. Bradu, T. Feuchter, G. Robinson, D. K. Griffin, and A. Podoleanu
Biomed. Opt. Express 8(11) 5139-5150 (2017)

Cancer field effects in normal tissues revealed by Raman spectroscopy

Chad A. Lieber, Hubert E. Nethercott, and Mustafa H. Kabeer
Biomed. Opt. Express 1(3) 975-982 (2010)

Evaluation of non-thermal plasma-induced anticancer effects on human colon cancer cells

Jae-Sun Choi, Jeongho Kim, Young-Jun Hong, Woom-Yee Bae, Eun Ha Choi, Joo-Won Jeong, and Hun-Kuk Park
Biomed. Opt. Express 8(5) 2649-2659 (2017)

References

  • View by:
  • |
  • |
  • |

  1. M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).
  2. A. S. Lopes, T. Greve, and H. Callesen, “Quantification of embryo quality by respirometry,” Theriogenology 67(1), 21–31 (2007).
    [Crossref] [PubMed]
  3. E. Seli, L. Botros, D. Sakkas, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 90(6), 2183–2189 (2008).
    [Crossref] [PubMed]
  4. D. R. Brison, F. D. Houghton, D. Falconer, S. A. Roberts, J. Hawkhead, P. G. Humpherson, B. A. Lieberman, and H. J. Leese, “Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover,” Hum. Reprod. 19(10), 2319–2324 (2004).
    [Crossref] [PubMed]
  5. C. G. Vergouw, L. L. Botros, P. Roos, J. W. Lens, R. Schats, P. G. A. Hompes, D. H. Burns, and C. B. Lambalk, “Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection,” Hum. Reprod. 23(7), 1499–1504 (2008).
    [Crossref] [PubMed]
  6. S. M. Pudakalakatti, S. Uppangala, F. D’Souza, G. Kalthur, P. Kumar, S. K. Adiga, and H. S. Atreya, “NMR studies of preimplantation embryo metabolism in human assisted reproductive techniques: a new biomarker for assessment of embryo implantation potential,” NMR Biomed. 26(1), 20–27 (2013).
    [Crossref] [PubMed]
  7. J. Herrero and M. Meseguer, “Selection of high potential embryos using time-lapse imaging: the era of morphokinetics,” Fertil. Steril. 99(4), 1030–1034 (2013).
    [Crossref] [PubMed]
  8. D. K. Gardner, M. Lane, J. Stevens, and W. B. Schoolcraft, “Noninvasive assessment of human embryo nutrient consumption as a measure of developmental potential,” Fertil. Steril. 76(6), 1175–1180 (2001).
    [Crossref] [PubMed]
  9. A. G. Shen, J. Peng, Q. H. Zhao, L. Su, X. H. Wang, J. M. Hu, and Q. Yang, “Accurate and noninvasive embryos screening during in vitro fertilization (IVF) assisted by Raman analysis of embryos culture medium,” Laser Phys. Lett. 9(4), 322–328 (2012).
    [Crossref]
  10. Q. Zhao, T. Yin, J. Peng, Y. Zou, J. Yang, A. Shen, and J. Hu, “Noninvasive Metabolomic Profiling of Human Embryo Culture Media Using a Simple Spectroscopy Adjunct to Morphology for Embryo Assessment in in Vitro Fertilization (IVF),” Int. J. Mol. Sci. 14(4), 6556–6570 (2013).
    [Crossref] [PubMed]
  11. D. K. Gardner and H. J. Leese, “Assessment of embryo viability prior to transfer by the noninvasive measurement of glucose uptake,” J. Exp. Zool. 242(1), 103–105 (1987).
    [Crossref] [PubMed]
  12. T. Hardarson, A. Ahlström, L. Rogberg, L. Botros, T. Hillensjö, G. Westlander, D. Sakkas, and M. Wikland, “Non-invasive metabolomic profiling of Day 2 and 5 embryo culture medium: a prospective randomized trial,” Hum. Reprod. 27(1), 89–96 (2012).
    [Crossref] [PubMed]
  13. Y. S. Lee, G. A. Thouas, and D. K. Gardner, “Developmental kinetics of cleavage stage mouse embryos are related to their subsequent carbohydrate and amino acid utilization at the blastocyst stage,” Hum. Reprod. 30(3), 543–552 (2015).
    [Crossref] [PubMed]
  14. M. Wallace, E. Cottell, J. Cullinane, F. M. McAuliffe, M. Wingfield, and L. Brennan, “(1)H NMR based metabolic profiling of day 2 spent embryo media correlates with implantation potential,” Syst. Biol. Reprod. Med. 60(1), 58–63 (2014).
    [Crossref] [PubMed]
  15. S. S. Cortezzi, E. C. Cabral, M. G. Trevisan, C. R. Ferreira, A. S. Setti, D. P. Braga, R. C. Figueira, A. Iaconelli, M. N. Eberlin, and E. Borges., “Prediction of embryo implantation potential by mass spectrometry fingerprinting of the culture medium,” Reproduction 145(5), 453–462 (2013).
    [Crossref] [PubMed]
  16. E. Seli, D. Sakkas, R. Scott, S. C. Kwok, S. M. Rosendahl, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 88(5), 1350–1357 (2007).
    [Crossref] [PubMed]
  17. Z. Huang, Y. Sun, J. Wang, S. Du, Y. Li, J. Lin, S. Feng, J. Lei, H. Lin, R. Chen, and H. Zeng, “Rapid and nondestructive method for evaluation of embryo culture media using drop coating deposition Raman spectroscopy,” J. Biomed. Opt. 18(12), 127003 (2013).
    [Crossref] [PubMed]
  18. R. Scott, E. Seli, K. Miller, D. Sakkas, K. Scott, and D. H. Burns, “Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot study,” Fertil. Steril. 90(1), 77–83 (2008).
    [Crossref] [PubMed]
  19. C. A. Soares, K. Annes, T. R. Dreyer, T. Magrini, M. T. Sonoda, H. da Silva Martinho, M. Nichi, M. E. d’Ávila Assumpção, and M. P. Milazzotto, “Photobiological effect of low-level laser irradiation in bovine embryo production system,” J. Biomed. Opt. 19(3), 035006 (2014).
    [Crossref] [PubMed]
  20. M. Wojdyr, “Fityk: a general-purpose peak fitting program,” J. Appl. Cryst. 43(5), 1126–1128 (2010).
    [Crossref]
  21. C. A. Martinez, A. Nohalez, C. Cuello, J. M. Vazquez, J. Roca, E. A. Martinez, and M. A. Gil, “The use of mineral oil during in vitro maturation, fertilization, and embryo culture does not impair the developmental competence of pig oocytes,” Theriogenology 83(4), 693–702 (2015).
    [Crossref] [PubMed]
  22. M. Shimada, N. Kawano, and T. Terada, “Delay of nuclear maturation and reduction in developmental competence of pig oocytes after mineral oil overlay of in vitro maturation media,” Reproduction 124(4), 557–564 (2002).
    [Crossref] [PubMed]
  23. P. B. D. Gonçalves, M. A. L. Oliveira, A. Mezzalira, M. M. Montagner, J. A. Visitin, and L. F. S. Costa, Biotécnicas aplicadas à reprodução animal (Roca, 2008).
  24. M. S. Bergholt, W. Zheng, K. Lin, K. Y. Ho, M. Teh, K. G. Yeoh, J. B. Yan So, and Z. Huang, “In vivo diagnosis of gastric cancer using Raman endoscopy and ant colony optimization techniques,” Int. J. Cancer 128(11), 2673–2680 (2011).
    [Crossref] [PubMed]
  25. A. Barth and C. Zscherp, “What vibrations tell us about proteins,” Q. Rev. Biophys. 35(4), 369–430 (2002).
    [Crossref] [PubMed]
  26. S. Cinta Pinzaru, A. Falamas, and C. A. Dehelean, “Molecular conformation changes along the malignancy revealed by optical nanosensors,” J. Cell. Mol. Med. 17(2), 277–286 (2013).
    [Crossref] [PubMed]
  27. Y. Zhou, C. H. Liu, Y. Sun, Y. Pu, S. Boydston-White, Y. Liu, and R. R. Alfano, “Human brain cancer studied by resonance Raman spectroscopy,” J. Biomed. Opt. 17(11), 116021 (2012).
    [Crossref] [PubMed]
  28. O. Samek, A. Jonáš, Z. Pilát, P. Zemánek, L. Nedbal, J. Tříska, P. Kotas, and M. Trtílek, “Raman Microspectroscopy of Individual Algal Cells: Sensing Unsaturation of Storage Lipids in vivo,” Sensors (Basel) 10(9), 8635–8651 (2010).
    [Crossref] [PubMed]
  29. L. Xue, P. Sun, D. Ou, P. Chen, M. Chen, and B. Yan, “Diagnosis of pathological minor salivary glands in primary Sjogren’s syndrome by using Raman spectroscopy,” Lasers Med. Sci. 29(2), 723–728 (2014).
    [Crossref] [PubMed]
  30. A. Moshaverinia, S. Ansari, Z. Movasaghi, R. W. Billington, J. A. Darr, and I. U. Rehman, “Modification of conventional glass-ionomer cements with N-vinylpyrrolidone containing polyacids, nano-hydroxy and fluoroapatite to improve mechanical properties,” Dent. Mater. 24(10), 1381–1390 (2008).
    [Crossref] [PubMed]

2015 (2)

Y. S. Lee, G. A. Thouas, and D. K. Gardner, “Developmental kinetics of cleavage stage mouse embryos are related to their subsequent carbohydrate and amino acid utilization at the blastocyst stage,” Hum. Reprod. 30(3), 543–552 (2015).
[Crossref] [PubMed]

C. A. Martinez, A. Nohalez, C. Cuello, J. M. Vazquez, J. Roca, E. A. Martinez, and M. A. Gil, “The use of mineral oil during in vitro maturation, fertilization, and embryo culture does not impair the developmental competence of pig oocytes,” Theriogenology 83(4), 693–702 (2015).
[Crossref] [PubMed]

2014 (4)

C. A. Soares, K. Annes, T. R. Dreyer, T. Magrini, M. T. Sonoda, H. da Silva Martinho, M. Nichi, M. E. d’Ávila Assumpção, and M. P. Milazzotto, “Photobiological effect of low-level laser irradiation in bovine embryo production system,” J. Biomed. Opt. 19(3), 035006 (2014).
[Crossref] [PubMed]

L. Xue, P. Sun, D. Ou, P. Chen, M. Chen, and B. Yan, “Diagnosis of pathological minor salivary glands in primary Sjogren’s syndrome by using Raman spectroscopy,” Lasers Med. Sci. 29(2), 723–728 (2014).
[Crossref] [PubMed]

M. Wallace, E. Cottell, J. Cullinane, F. M. McAuliffe, M. Wingfield, and L. Brennan, “(1)H NMR based metabolic profiling of day 2 spent embryo media correlates with implantation potential,” Syst. Biol. Reprod. Med. 60(1), 58–63 (2014).
[Crossref] [PubMed]

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

2013 (6)

S. M. Pudakalakatti, S. Uppangala, F. D’Souza, G. Kalthur, P. Kumar, S. K. Adiga, and H. S. Atreya, “NMR studies of preimplantation embryo metabolism in human assisted reproductive techniques: a new biomarker for assessment of embryo implantation potential,” NMR Biomed. 26(1), 20–27 (2013).
[Crossref] [PubMed]

J. Herrero and M. Meseguer, “Selection of high potential embryos using time-lapse imaging: the era of morphokinetics,” Fertil. Steril. 99(4), 1030–1034 (2013).
[Crossref] [PubMed]

S. S. Cortezzi, E. C. Cabral, M. G. Trevisan, C. R. Ferreira, A. S. Setti, D. P. Braga, R. C. Figueira, A. Iaconelli, M. N. Eberlin, and E. Borges., “Prediction of embryo implantation potential by mass spectrometry fingerprinting of the culture medium,” Reproduction 145(5), 453–462 (2013).
[Crossref] [PubMed]

Q. Zhao, T. Yin, J. Peng, Y. Zou, J. Yang, A. Shen, and J. Hu, “Noninvasive Metabolomic Profiling of Human Embryo Culture Media Using a Simple Spectroscopy Adjunct to Morphology for Embryo Assessment in in Vitro Fertilization (IVF),” Int. J. Mol. Sci. 14(4), 6556–6570 (2013).
[Crossref] [PubMed]

Z. Huang, Y. Sun, J. Wang, S. Du, Y. Li, J. Lin, S. Feng, J. Lei, H. Lin, R. Chen, and H. Zeng, “Rapid and nondestructive method for evaluation of embryo culture media using drop coating deposition Raman spectroscopy,” J. Biomed. Opt. 18(12), 127003 (2013).
[Crossref] [PubMed]

S. Cinta Pinzaru, A. Falamas, and C. A. Dehelean, “Molecular conformation changes along the malignancy revealed by optical nanosensors,” J. Cell. Mol. Med. 17(2), 277–286 (2013).
[Crossref] [PubMed]

2012 (3)

Y. Zhou, C. H. Liu, Y. Sun, Y. Pu, S. Boydston-White, Y. Liu, and R. R. Alfano, “Human brain cancer studied by resonance Raman spectroscopy,” J. Biomed. Opt. 17(11), 116021 (2012).
[Crossref] [PubMed]

T. Hardarson, A. Ahlström, L. Rogberg, L. Botros, T. Hillensjö, G. Westlander, D. Sakkas, and M. Wikland, “Non-invasive metabolomic profiling of Day 2 and 5 embryo culture medium: a prospective randomized trial,” Hum. Reprod. 27(1), 89–96 (2012).
[Crossref] [PubMed]

A. G. Shen, J. Peng, Q. H. Zhao, L. Su, X. H. Wang, J. M. Hu, and Q. Yang, “Accurate and noninvasive embryos screening during in vitro fertilization (IVF) assisted by Raman analysis of embryos culture medium,” Laser Phys. Lett. 9(4), 322–328 (2012).
[Crossref]

2011 (1)

M. S. Bergholt, W. Zheng, K. Lin, K. Y. Ho, M. Teh, K. G. Yeoh, J. B. Yan So, and Z. Huang, “In vivo diagnosis of gastric cancer using Raman endoscopy and ant colony optimization techniques,” Int. J. Cancer 128(11), 2673–2680 (2011).
[Crossref] [PubMed]

2010 (2)

O. Samek, A. Jonáš, Z. Pilát, P. Zemánek, L. Nedbal, J. Tříska, P. Kotas, and M. Trtílek, “Raman Microspectroscopy of Individual Algal Cells: Sensing Unsaturation of Storage Lipids in vivo,” Sensors (Basel) 10(9), 8635–8651 (2010).
[Crossref] [PubMed]

M. Wojdyr, “Fityk: a general-purpose peak fitting program,” J. Appl. Cryst. 43(5), 1126–1128 (2010).
[Crossref]

2008 (4)

A. Moshaverinia, S. Ansari, Z. Movasaghi, R. W. Billington, J. A. Darr, and I. U. Rehman, “Modification of conventional glass-ionomer cements with N-vinylpyrrolidone containing polyacids, nano-hydroxy and fluoroapatite to improve mechanical properties,” Dent. Mater. 24(10), 1381–1390 (2008).
[Crossref] [PubMed]

C. G. Vergouw, L. L. Botros, P. Roos, J. W. Lens, R. Schats, P. G. A. Hompes, D. H. Burns, and C. B. Lambalk, “Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection,” Hum. Reprod. 23(7), 1499–1504 (2008).
[Crossref] [PubMed]

E. Seli, L. Botros, D. Sakkas, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 90(6), 2183–2189 (2008).
[Crossref] [PubMed]

R. Scott, E. Seli, K. Miller, D. Sakkas, K. Scott, and D. H. Burns, “Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot study,” Fertil. Steril. 90(1), 77–83 (2008).
[Crossref] [PubMed]

2007 (2)

E. Seli, D. Sakkas, R. Scott, S. C. Kwok, S. M. Rosendahl, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 88(5), 1350–1357 (2007).
[Crossref] [PubMed]

A. S. Lopes, T. Greve, and H. Callesen, “Quantification of embryo quality by respirometry,” Theriogenology 67(1), 21–31 (2007).
[Crossref] [PubMed]

2004 (1)

D. R. Brison, F. D. Houghton, D. Falconer, S. A. Roberts, J. Hawkhead, P. G. Humpherson, B. A. Lieberman, and H. J. Leese, “Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover,” Hum. Reprod. 19(10), 2319–2324 (2004).
[Crossref] [PubMed]

2002 (2)

M. Shimada, N. Kawano, and T. Terada, “Delay of nuclear maturation and reduction in developmental competence of pig oocytes after mineral oil overlay of in vitro maturation media,” Reproduction 124(4), 557–564 (2002).
[Crossref] [PubMed]

A. Barth and C. Zscherp, “What vibrations tell us about proteins,” Q. Rev. Biophys. 35(4), 369–430 (2002).
[Crossref] [PubMed]

2001 (1)

D. K. Gardner, M. Lane, J. Stevens, and W. B. Schoolcraft, “Noninvasive assessment of human embryo nutrient consumption as a measure of developmental potential,” Fertil. Steril. 76(6), 1175–1180 (2001).
[Crossref] [PubMed]

1987 (1)

D. K. Gardner and H. J. Leese, “Assessment of embryo viability prior to transfer by the noninvasive measurement of glucose uptake,” J. Exp. Zool. 242(1), 103–105 (1987).
[Crossref] [PubMed]

Adiga, S. K.

S. M. Pudakalakatti, S. Uppangala, F. D’Souza, G. Kalthur, P. Kumar, S. K. Adiga, and H. S. Atreya, “NMR studies of preimplantation embryo metabolism in human assisted reproductive techniques: a new biomarker for assessment of embryo implantation potential,” NMR Biomed. 26(1), 20–27 (2013).
[Crossref] [PubMed]

Ahlström, A.

T. Hardarson, A. Ahlström, L. Rogberg, L. Botros, T. Hillensjö, G. Westlander, D. Sakkas, and M. Wikland, “Non-invasive metabolomic profiling of Day 2 and 5 embryo culture medium: a prospective randomized trial,” Hum. Reprod. 27(1), 89–96 (2012).
[Crossref] [PubMed]

Alfano, R. R.

Y. Zhou, C. H. Liu, Y. Sun, Y. Pu, S. Boydston-White, Y. Liu, and R. R. Alfano, “Human brain cancer studied by resonance Raman spectroscopy,” J. Biomed. Opt. 17(11), 116021 (2012).
[Crossref] [PubMed]

Annes, K.

C. A. Soares, K. Annes, T. R. Dreyer, T. Magrini, M. T. Sonoda, H. da Silva Martinho, M. Nichi, M. E. d’Ávila Assumpção, and M. P. Milazzotto, “Photobiological effect of low-level laser irradiation in bovine embryo production system,” J. Biomed. Opt. 19(3), 035006 (2014).
[Crossref] [PubMed]

Ansari, S.

A. Moshaverinia, S. Ansari, Z. Movasaghi, R. W. Billington, J. A. Darr, and I. U. Rehman, “Modification of conventional glass-ionomer cements with N-vinylpyrrolidone containing polyacids, nano-hydroxy and fluoroapatite to improve mechanical properties,” Dent. Mater. 24(10), 1381–1390 (2008).
[Crossref] [PubMed]

Atreya, H. S.

S. M. Pudakalakatti, S. Uppangala, F. D’Souza, G. Kalthur, P. Kumar, S. K. Adiga, and H. S. Atreya, “NMR studies of preimplantation embryo metabolism in human assisted reproductive techniques: a new biomarker for assessment of embryo implantation potential,” NMR Biomed. 26(1), 20–27 (2013).
[Crossref] [PubMed]

Barth, A.

A. Barth and C. Zscherp, “What vibrations tell us about proteins,” Q. Rev. Biophys. 35(4), 369–430 (2002).
[Crossref] [PubMed]

Bergholt, M. S.

M. S. Bergholt, W. Zheng, K. Lin, K. Y. Ho, M. Teh, K. G. Yeoh, J. B. Yan So, and Z. Huang, “In vivo diagnosis of gastric cancer using Raman endoscopy and ant colony optimization techniques,” Int. J. Cancer 128(11), 2673–2680 (2011).
[Crossref] [PubMed]

Billington, R. W.

A. Moshaverinia, S. Ansari, Z. Movasaghi, R. W. Billington, J. A. Darr, and I. U. Rehman, “Modification of conventional glass-ionomer cements with N-vinylpyrrolidone containing polyacids, nano-hydroxy and fluoroapatite to improve mechanical properties,” Dent. Mater. 24(10), 1381–1390 (2008).
[Crossref] [PubMed]

Borges, E.

S. S. Cortezzi, E. C. Cabral, M. G. Trevisan, C. R. Ferreira, A. S. Setti, D. P. Braga, R. C. Figueira, A. Iaconelli, M. N. Eberlin, and E. Borges., “Prediction of embryo implantation potential by mass spectrometry fingerprinting of the culture medium,” Reproduction 145(5), 453–462 (2013).
[Crossref] [PubMed]

Botros, L.

T. Hardarson, A. Ahlström, L. Rogberg, L. Botros, T. Hillensjö, G. Westlander, D. Sakkas, and M. Wikland, “Non-invasive metabolomic profiling of Day 2 and 5 embryo culture medium: a prospective randomized trial,” Hum. Reprod. 27(1), 89–96 (2012).
[Crossref] [PubMed]

E. Seli, L. Botros, D. Sakkas, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 90(6), 2183–2189 (2008).
[Crossref] [PubMed]

Botros, L. L.

C. G. Vergouw, L. L. Botros, P. Roos, J. W. Lens, R. Schats, P. G. A. Hompes, D. H. Burns, and C. B. Lambalk, “Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection,” Hum. Reprod. 23(7), 1499–1504 (2008).
[Crossref] [PubMed]

Boydston-White, S.

Y. Zhou, C. H. Liu, Y. Sun, Y. Pu, S. Boydston-White, Y. Liu, and R. R. Alfano, “Human brain cancer studied by resonance Raman spectroscopy,” J. Biomed. Opt. 17(11), 116021 (2012).
[Crossref] [PubMed]

Braga, D. P.

S. S. Cortezzi, E. C. Cabral, M. G. Trevisan, C. R. Ferreira, A. S. Setti, D. P. Braga, R. C. Figueira, A. Iaconelli, M. N. Eberlin, and E. Borges., “Prediction of embryo implantation potential by mass spectrometry fingerprinting of the culture medium,” Reproduction 145(5), 453–462 (2013).
[Crossref] [PubMed]

Brennan, L.

M. Wallace, E. Cottell, J. Cullinane, F. M. McAuliffe, M. Wingfield, and L. Brennan, “(1)H NMR based metabolic profiling of day 2 spent embryo media correlates with implantation potential,” Syst. Biol. Reprod. Med. 60(1), 58–63 (2014).
[Crossref] [PubMed]

Brison, D. R.

D. R. Brison, F. D. Houghton, D. Falconer, S. A. Roberts, J. Hawkhead, P. G. Humpherson, B. A. Lieberman, and H. J. Leese, “Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover,” Hum. Reprod. 19(10), 2319–2324 (2004).
[Crossref] [PubMed]

Burns, D. H.

C. G. Vergouw, L. L. Botros, P. Roos, J. W. Lens, R. Schats, P. G. A. Hompes, D. H. Burns, and C. B. Lambalk, “Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection,” Hum. Reprod. 23(7), 1499–1504 (2008).
[Crossref] [PubMed]

E. Seli, L. Botros, D. Sakkas, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 90(6), 2183–2189 (2008).
[Crossref] [PubMed]

R. Scott, E. Seli, K. Miller, D. Sakkas, K. Scott, and D. H. Burns, “Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot study,” Fertil. Steril. 90(1), 77–83 (2008).
[Crossref] [PubMed]

E. Seli, D. Sakkas, R. Scott, S. C. Kwok, S. M. Rosendahl, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 88(5), 1350–1357 (2007).
[Crossref] [PubMed]

Caamaño, J. N.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

Cabral, E. C.

S. S. Cortezzi, E. C. Cabral, M. G. Trevisan, C. R. Ferreira, A. S. Setti, D. P. Braga, R. C. Figueira, A. Iaconelli, M. N. Eberlin, and E. Borges., “Prediction of embryo implantation potential by mass spectrometry fingerprinting of the culture medium,” Reproduction 145(5), 453–462 (2013).
[Crossref] [PubMed]

Callesen, H.

A. S. Lopes, T. Greve, and H. Callesen, “Quantification of embryo quality by respirometry,” Theriogenology 67(1), 21–31 (2007).
[Crossref] [PubMed]

Carrocera, S.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

Chen, M.

L. Xue, P. Sun, D. Ou, P. Chen, M. Chen, and B. Yan, “Diagnosis of pathological minor salivary glands in primary Sjogren’s syndrome by using Raman spectroscopy,” Lasers Med. Sci. 29(2), 723–728 (2014).
[Crossref] [PubMed]

Chen, P.

L. Xue, P. Sun, D. Ou, P. Chen, M. Chen, and B. Yan, “Diagnosis of pathological minor salivary glands in primary Sjogren’s syndrome by using Raman spectroscopy,” Lasers Med. Sci. 29(2), 723–728 (2014).
[Crossref] [PubMed]

Chen, R.

Z. Huang, Y. Sun, J. Wang, S. Du, Y. Li, J. Lin, S. Feng, J. Lei, H. Lin, R. Chen, and H. Zeng, “Rapid and nondestructive method for evaluation of embryo culture media using drop coating deposition Raman spectroscopy,” J. Biomed. Opt. 18(12), 127003 (2013).
[Crossref] [PubMed]

Cinta Pinzaru, S.

S. Cinta Pinzaru, A. Falamas, and C. A. Dehelean, “Molecular conformation changes along the malignancy revealed by optical nanosensors,” J. Cell. Mol. Med. 17(2), 277–286 (2013).
[Crossref] [PubMed]

Correia, E.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

Cortezzi, S. S.

S. S. Cortezzi, E. C. Cabral, M. G. Trevisan, C. R. Ferreira, A. S. Setti, D. P. Braga, R. C. Figueira, A. Iaconelli, M. N. Eberlin, and E. Borges., “Prediction of embryo implantation potential by mass spectrometry fingerprinting of the culture medium,” Reproduction 145(5), 453–462 (2013).
[Crossref] [PubMed]

Cottell, E.

M. Wallace, E. Cottell, J. Cullinane, F. M. McAuliffe, M. Wingfield, and L. Brennan, “(1)H NMR based metabolic profiling of day 2 spent embryo media correlates with implantation potential,” Syst. Biol. Reprod. Med. 60(1), 58–63 (2014).
[Crossref] [PubMed]

Cuello, C.

C. A. Martinez, A. Nohalez, C. Cuello, J. M. Vazquez, J. Roca, E. A. Martinez, and M. A. Gil, “The use of mineral oil during in vitro maturation, fertilization, and embryo culture does not impair the developmental competence of pig oocytes,” Theriogenology 83(4), 693–702 (2015).
[Crossref] [PubMed]

Cullinane, J.

M. Wallace, E. Cottell, J. Cullinane, F. M. McAuliffe, M. Wingfield, and L. Brennan, “(1)H NMR based metabolic profiling of day 2 spent embryo media correlates with implantation potential,” Syst. Biol. Reprod. Med. 60(1), 58–63 (2014).
[Crossref] [PubMed]

d’Ávila Assumpção, M. E.

C. A. Soares, K. Annes, T. R. Dreyer, T. Magrini, M. T. Sonoda, H. da Silva Martinho, M. Nichi, M. E. d’Ávila Assumpção, and M. P. Milazzotto, “Photobiological effect of low-level laser irradiation in bovine embryo production system,” J. Biomed. Opt. 19(3), 035006 (2014).
[Crossref] [PubMed]

D’Souza, F.

S. M. Pudakalakatti, S. Uppangala, F. D’Souza, G. Kalthur, P. Kumar, S. K. Adiga, and H. S. Atreya, “NMR studies of preimplantation embryo metabolism in human assisted reproductive techniques: a new biomarker for assessment of embryo implantation potential,” NMR Biomed. 26(1), 20–27 (2013).
[Crossref] [PubMed]

da Silva Martinho, H.

C. A. Soares, K. Annes, T. R. Dreyer, T. Magrini, M. T. Sonoda, H. da Silva Martinho, M. Nichi, M. E. d’Ávila Assumpção, and M. P. Milazzotto, “Photobiological effect of low-level laser irradiation in bovine embryo production system,” J. Biomed. Opt. 19(3), 035006 (2014).
[Crossref] [PubMed]

Darr, J. A.

A. Moshaverinia, S. Ansari, Z. Movasaghi, R. W. Billington, J. A. Darr, and I. U. Rehman, “Modification of conventional glass-ionomer cements with N-vinylpyrrolidone containing polyacids, nano-hydroxy and fluoroapatite to improve mechanical properties,” Dent. Mater. 24(10), 1381–1390 (2008).
[Crossref] [PubMed]

Dehelean, C. A.

S. Cinta Pinzaru, A. Falamas, and C. A. Dehelean, “Molecular conformation changes along the malignancy revealed by optical nanosensors,” J. Cell. Mol. Med. 17(2), 277–286 (2013).
[Crossref] [PubMed]

Diez, C.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

Dreyer, T. R.

C. A. Soares, K. Annes, T. R. Dreyer, T. Magrini, M. T. Sonoda, H. da Silva Martinho, M. Nichi, M. E. d’Ávila Assumpção, and M. P. Milazzotto, “Photobiological effect of low-level laser irradiation in bovine embryo production system,” J. Biomed. Opt. 19(3), 035006 (2014).
[Crossref] [PubMed]

Du, S.

Z. Huang, Y. Sun, J. Wang, S. Du, Y. Li, J. Lin, S. Feng, J. Lei, H. Lin, R. Chen, and H. Zeng, “Rapid and nondestructive method for evaluation of embryo culture media using drop coating deposition Raman spectroscopy,” J. Biomed. Opt. 18(12), 127003 (2013).
[Crossref] [PubMed]

Eberlin, M. N.

S. S. Cortezzi, E. C. Cabral, M. G. Trevisan, C. R. Ferreira, A. S. Setti, D. P. Braga, R. C. Figueira, A. Iaconelli, M. N. Eberlin, and E. Borges., “Prediction of embryo implantation potential by mass spectrometry fingerprinting of the culture medium,” Reproduction 145(5), 453–462 (2013).
[Crossref] [PubMed]

Falamas, A.

S. Cinta Pinzaru, A. Falamas, and C. A. Dehelean, “Molecular conformation changes along the malignancy revealed by optical nanosensors,” J. Cell. Mol. Med. 17(2), 277–286 (2013).
[Crossref] [PubMed]

Falconer, D.

D. R. Brison, F. D. Houghton, D. Falconer, S. A. Roberts, J. Hawkhead, P. G. Humpherson, B. A. Lieberman, and H. J. Leese, “Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover,” Hum. Reprod. 19(10), 2319–2324 (2004).
[Crossref] [PubMed]

Feng, S.

Z. Huang, Y. Sun, J. Wang, S. Du, Y. Li, J. Lin, S. Feng, J. Lei, H. Lin, R. Chen, and H. Zeng, “Rapid and nondestructive method for evaluation of embryo culture media using drop coating deposition Raman spectroscopy,” J. Biomed. Opt. 18(12), 127003 (2013).
[Crossref] [PubMed]

Fernandez-gonzales, A.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

Ferreira, C. R.

S. S. Cortezzi, E. C. Cabral, M. G. Trevisan, C. R. Ferreira, A. S. Setti, D. P. Braga, R. C. Figueira, A. Iaconelli, M. N. Eberlin, and E. Borges., “Prediction of embryo implantation potential by mass spectrometry fingerprinting of the culture medium,” Reproduction 145(5), 453–462 (2013).
[Crossref] [PubMed]

Figueira, R. C.

S. S. Cortezzi, E. C. Cabral, M. G. Trevisan, C. R. Ferreira, A. S. Setti, D. P. Braga, R. C. Figueira, A. Iaconelli, M. N. Eberlin, and E. Borges., “Prediction of embryo implantation potential by mass spectrometry fingerprinting of the culture medium,” Reproduction 145(5), 453–462 (2013).
[Crossref] [PubMed]

Gardner, D. K.

Y. S. Lee, G. A. Thouas, and D. K. Gardner, “Developmental kinetics of cleavage stage mouse embryos are related to their subsequent carbohydrate and amino acid utilization at the blastocyst stage,” Hum. Reprod. 30(3), 543–552 (2015).
[Crossref] [PubMed]

D. K. Gardner, M. Lane, J. Stevens, and W. B. Schoolcraft, “Noninvasive assessment of human embryo nutrient consumption as a measure of developmental potential,” Fertil. Steril. 76(6), 1175–1180 (2001).
[Crossref] [PubMed]

D. K. Gardner and H. J. Leese, “Assessment of embryo viability prior to transfer by the noninvasive measurement of glucose uptake,” J. Exp. Zool. 242(1), 103–105 (1987).
[Crossref] [PubMed]

Gil, M. A.

C. A. Martinez, A. Nohalez, C. Cuello, J. M. Vazquez, J. Roca, E. A. Martinez, and M. A. Gil, “The use of mineral oil during in vitro maturation, fertilization, and embryo culture does not impair the developmental competence of pig oocytes,” Theriogenology 83(4), 693–702 (2015).
[Crossref] [PubMed]

Gomez, E.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

Greve, T.

A. S. Lopes, T. Greve, and H. Callesen, “Quantification of embryo quality by respirometry,” Theriogenology 67(1), 21–31 (2007).
[Crossref] [PubMed]

Guyader-joly, C.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

Hardarson, T.

T. Hardarson, A. Ahlström, L. Rogberg, L. Botros, T. Hillensjö, G. Westlander, D. Sakkas, and M. Wikland, “Non-invasive metabolomic profiling of Day 2 and 5 embryo culture medium: a prospective randomized trial,” Hum. Reprod. 27(1), 89–96 (2012).
[Crossref] [PubMed]

Hawkhead, J.

D. R. Brison, F. D. Houghton, D. Falconer, S. A. Roberts, J. Hawkhead, P. G. Humpherson, B. A. Lieberman, and H. J. Leese, “Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover,” Hum. Reprod. 19(10), 2319–2324 (2004).
[Crossref] [PubMed]

Herrero, J.

J. Herrero and M. Meseguer, “Selection of high potential embryos using time-lapse imaging: the era of morphokinetics,” Fertil. Steril. 99(4), 1030–1034 (2013).
[Crossref] [PubMed]

Hillensjö, T.

T. Hardarson, A. Ahlström, L. Rogberg, L. Botros, T. Hillensjö, G. Westlander, D. Sakkas, and M. Wikland, “Non-invasive metabolomic profiling of Day 2 and 5 embryo culture medium: a prospective randomized trial,” Hum. Reprod. 27(1), 89–96 (2012).
[Crossref] [PubMed]

Ho, K. Y.

M. S. Bergholt, W. Zheng, K. Lin, K. Y. Ho, M. Teh, K. G. Yeoh, J. B. Yan So, and Z. Huang, “In vivo diagnosis of gastric cancer using Raman endoscopy and ant colony optimization techniques,” Int. J. Cancer 128(11), 2673–2680 (2011).
[Crossref] [PubMed]

Hompes, P. G. A.

C. G. Vergouw, L. L. Botros, P. Roos, J. W. Lens, R. Schats, P. G. A. Hompes, D. H. Burns, and C. B. Lambalk, “Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection,” Hum. Reprod. 23(7), 1499–1504 (2008).
[Crossref] [PubMed]

Houghton, F. D.

D. R. Brison, F. D. Houghton, D. Falconer, S. A. Roberts, J. Hawkhead, P. G. Humpherson, B. A. Lieberman, and H. J. Leese, “Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover,” Hum. Reprod. 19(10), 2319–2324 (2004).
[Crossref] [PubMed]

Hu, J.

Q. Zhao, T. Yin, J. Peng, Y. Zou, J. Yang, A. Shen, and J. Hu, “Noninvasive Metabolomic Profiling of Human Embryo Culture Media Using a Simple Spectroscopy Adjunct to Morphology for Embryo Assessment in in Vitro Fertilization (IVF),” Int. J. Mol. Sci. 14(4), 6556–6570 (2013).
[Crossref] [PubMed]

Hu, J. M.

A. G. Shen, J. Peng, Q. H. Zhao, L. Su, X. H. Wang, J. M. Hu, and Q. Yang, “Accurate and noninvasive embryos screening during in vitro fertilization (IVF) assisted by Raman analysis of embryos culture medium,” Laser Phys. Lett. 9(4), 322–328 (2012).
[Crossref]

Huang, Z.

Z. Huang, Y. Sun, J. Wang, S. Du, Y. Li, J. Lin, S. Feng, J. Lei, H. Lin, R. Chen, and H. Zeng, “Rapid and nondestructive method for evaluation of embryo culture media using drop coating deposition Raman spectroscopy,” J. Biomed. Opt. 18(12), 127003 (2013).
[Crossref] [PubMed]

M. S. Bergholt, W. Zheng, K. Lin, K. Y. Ho, M. Teh, K. G. Yeoh, J. B. Yan So, and Z. Huang, “In vivo diagnosis of gastric cancer using Raman endoscopy and ant colony optimization techniques,” Int. J. Cancer 128(11), 2673–2680 (2011).
[Crossref] [PubMed]

Humblot, P.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

Humpherson, P. G.

D. R. Brison, F. D. Houghton, D. Falconer, S. A. Roberts, J. Hawkhead, P. G. Humpherson, B. A. Lieberman, and H. J. Leese, “Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover,” Hum. Reprod. 19(10), 2319–2324 (2004).
[Crossref] [PubMed]

Iaconelli, A.

S. S. Cortezzi, E. C. Cabral, M. G. Trevisan, C. R. Ferreira, A. S. Setti, D. P. Braga, R. C. Figueira, A. Iaconelli, M. N. Eberlin, and E. Borges., “Prediction of embryo implantation potential by mass spectrometry fingerprinting of the culture medium,” Reproduction 145(5), 453–462 (2013).
[Crossref] [PubMed]

Jonáš, A.

O. Samek, A. Jonáš, Z. Pilát, P. Zemánek, L. Nedbal, J. Tříska, P. Kotas, and M. Trtílek, “Raman Microspectroscopy of Individual Algal Cells: Sensing Unsaturation of Storage Lipids in vivo,” Sensors (Basel) 10(9), 8635–8651 (2010).
[Crossref] [PubMed]

Kalthur, G.

S. M. Pudakalakatti, S. Uppangala, F. D’Souza, G. Kalthur, P. Kumar, S. K. Adiga, and H. S. Atreya, “NMR studies of preimplantation embryo metabolism in human assisted reproductive techniques: a new biomarker for assessment of embryo implantation potential,” NMR Biomed. 26(1), 20–27 (2013).
[Crossref] [PubMed]

Kawano, N.

M. Shimada, N. Kawano, and T. Terada, “Delay of nuclear maturation and reduction in developmental competence of pig oocytes after mineral oil overlay of in vitro maturation media,” Reproduction 124(4), 557–564 (2002).
[Crossref] [PubMed]

Kotas, P.

O. Samek, A. Jonáš, Z. Pilát, P. Zemánek, L. Nedbal, J. Tříska, P. Kotas, and M. Trtílek, “Raman Microspectroscopy of Individual Algal Cells: Sensing Unsaturation of Storage Lipids in vivo,” Sensors (Basel) 10(9), 8635–8651 (2010).
[Crossref] [PubMed]

Kumar, P.

S. M. Pudakalakatti, S. Uppangala, F. D’Souza, G. Kalthur, P. Kumar, S. K. Adiga, and H. S. Atreya, “NMR studies of preimplantation embryo metabolism in human assisted reproductive techniques: a new biomarker for assessment of embryo implantation potential,” NMR Biomed. 26(1), 20–27 (2013).
[Crossref] [PubMed]

Kwok, S. C.

E. Seli, D. Sakkas, R. Scott, S. C. Kwok, S. M. Rosendahl, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 88(5), 1350–1357 (2007).
[Crossref] [PubMed]

Lambalk, C. B.

C. G. Vergouw, L. L. Botros, P. Roos, J. W. Lens, R. Schats, P. G. A. Hompes, D. H. Burns, and C. B. Lambalk, “Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection,” Hum. Reprod. 23(7), 1499–1504 (2008).
[Crossref] [PubMed]

Lane, M.

D. K. Gardner, M. Lane, J. Stevens, and W. B. Schoolcraft, “Noninvasive assessment of human embryo nutrient consumption as a measure of developmental potential,” Fertil. Steril. 76(6), 1175–1180 (2001).
[Crossref] [PubMed]

Lee, Y. S.

Y. S. Lee, G. A. Thouas, and D. K. Gardner, “Developmental kinetics of cleavage stage mouse embryos are related to their subsequent carbohydrate and amino acid utilization at the blastocyst stage,” Hum. Reprod. 30(3), 543–552 (2015).
[Crossref] [PubMed]

Leese, H. J.

D. R. Brison, F. D. Houghton, D. Falconer, S. A. Roberts, J. Hawkhead, P. G. Humpherson, B. A. Lieberman, and H. J. Leese, “Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover,” Hum. Reprod. 19(10), 2319–2324 (2004).
[Crossref] [PubMed]

D. K. Gardner and H. J. Leese, “Assessment of embryo viability prior to transfer by the noninvasive measurement of glucose uptake,” J. Exp. Zool. 242(1), 103–105 (1987).
[Crossref] [PubMed]

Lei, J.

Z. Huang, Y. Sun, J. Wang, S. Du, Y. Li, J. Lin, S. Feng, J. Lei, H. Lin, R. Chen, and H. Zeng, “Rapid and nondestructive method for evaluation of embryo culture media using drop coating deposition Raman spectroscopy,” J. Biomed. Opt. 18(12), 127003 (2013).
[Crossref] [PubMed]

Lens, J. W.

C. G. Vergouw, L. L. Botros, P. Roos, J. W. Lens, R. Schats, P. G. A. Hompes, D. H. Burns, and C. B. Lambalk, “Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection,” Hum. Reprod. 23(7), 1499–1504 (2008).
[Crossref] [PubMed]

Li, Y.

Z. Huang, Y. Sun, J. Wang, S. Du, Y. Li, J. Lin, S. Feng, J. Lei, H. Lin, R. Chen, and H. Zeng, “Rapid and nondestructive method for evaluation of embryo culture media using drop coating deposition Raman spectroscopy,” J. Biomed. Opt. 18(12), 127003 (2013).
[Crossref] [PubMed]

Lieberman, B. A.

D. R. Brison, F. D. Houghton, D. Falconer, S. A. Roberts, J. Hawkhead, P. G. Humpherson, B. A. Lieberman, and H. J. Leese, “Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover,” Hum. Reprod. 19(10), 2319–2324 (2004).
[Crossref] [PubMed]

Lin, H.

Z. Huang, Y. Sun, J. Wang, S. Du, Y. Li, J. Lin, S. Feng, J. Lei, H. Lin, R. Chen, and H. Zeng, “Rapid and nondestructive method for evaluation of embryo culture media using drop coating deposition Raman spectroscopy,” J. Biomed. Opt. 18(12), 127003 (2013).
[Crossref] [PubMed]

Lin, J.

Z. Huang, Y. Sun, J. Wang, S. Du, Y. Li, J. Lin, S. Feng, J. Lei, H. Lin, R. Chen, and H. Zeng, “Rapid and nondestructive method for evaluation of embryo culture media using drop coating deposition Raman spectroscopy,” J. Biomed. Opt. 18(12), 127003 (2013).
[Crossref] [PubMed]

Lin, K.

M. S. Bergholt, W. Zheng, K. Lin, K. Y. Ho, M. Teh, K. G. Yeoh, J. B. Yan So, and Z. Huang, “In vivo diagnosis of gastric cancer using Raman endoscopy and ant colony optimization techniques,” Int. J. Cancer 128(11), 2673–2680 (2011).
[Crossref] [PubMed]

Liu, C. H.

Y. Zhou, C. H. Liu, Y. Sun, Y. Pu, S. Boydston-White, Y. Liu, and R. R. Alfano, “Human brain cancer studied by resonance Raman spectroscopy,” J. Biomed. Opt. 17(11), 116021 (2012).
[Crossref] [PubMed]

Liu, Y.

Y. Zhou, C. H. Liu, Y. Sun, Y. Pu, S. Boydston-White, Y. Liu, and R. R. Alfano, “Human brain cancer studied by resonance Raman spectroscopy,” J. Biomed. Opt. 17(11), 116021 (2012).
[Crossref] [PubMed]

Lopes, A. S.

A. S. Lopes, T. Greve, and H. Callesen, “Quantification of embryo quality by respirometry,” Theriogenology 67(1), 21–31 (2007).
[Crossref] [PubMed]

Magrini, T.

C. A. Soares, K. Annes, T. R. Dreyer, T. Magrini, M. T. Sonoda, H. da Silva Martinho, M. Nichi, M. E. d’Ávila Assumpção, and M. P. Milazzotto, “Photobiological effect of low-level laser irradiation in bovine embryo production system,” J. Biomed. Opt. 19(3), 035006 (2014).
[Crossref] [PubMed]

Marquant Le Guienne, B.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

Martin, D.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

Martinez, C. A.

C. A. Martinez, A. Nohalez, C. Cuello, J. M. Vazquez, J. Roca, E. A. Martinez, and M. A. Gil, “The use of mineral oil during in vitro maturation, fertilization, and embryo culture does not impair the developmental competence of pig oocytes,” Theriogenology 83(4), 693–702 (2015).
[Crossref] [PubMed]

Martinez, E. A.

C. A. Martinez, A. Nohalez, C. Cuello, J. M. Vazquez, J. Roca, E. A. Martinez, and M. A. Gil, “The use of mineral oil during in vitro maturation, fertilization, and embryo culture does not impair the developmental competence of pig oocytes,” Theriogenology 83(4), 693–702 (2015).
[Crossref] [PubMed]

Martinez-bello, D.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

McAuliffe, F. M.

M. Wallace, E. Cottell, J. Cullinane, F. M. McAuliffe, M. Wingfield, and L. Brennan, “(1)H NMR based metabolic profiling of day 2 spent embryo media correlates with implantation potential,” Syst. Biol. Reprod. Med. 60(1), 58–63 (2014).
[Crossref] [PubMed]

Meseguer, M.

J. Herrero and M. Meseguer, “Selection of high potential embryos using time-lapse imaging: the era of morphokinetics,” Fertil. Steril. 99(4), 1030–1034 (2013).
[Crossref] [PubMed]

Milazzotto, M. P.

C. A. Soares, K. Annes, T. R. Dreyer, T. Magrini, M. T. Sonoda, H. da Silva Martinho, M. Nichi, M. E. d’Ávila Assumpção, and M. P. Milazzotto, “Photobiological effect of low-level laser irradiation in bovine embryo production system,” J. Biomed. Opt. 19(3), 035006 (2014).
[Crossref] [PubMed]

Miller, K.

R. Scott, E. Seli, K. Miller, D. Sakkas, K. Scott, and D. H. Burns, “Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot study,” Fertil. Steril. 90(1), 77–83 (2008).
[Crossref] [PubMed]

Moshaverinia, A.

A. Moshaverinia, S. Ansari, Z. Movasaghi, R. W. Billington, J. A. Darr, and I. U. Rehman, “Modification of conventional glass-ionomer cements with N-vinylpyrrolidone containing polyacids, nano-hydroxy and fluoroapatite to improve mechanical properties,” Dent. Mater. 24(10), 1381–1390 (2008).
[Crossref] [PubMed]

Movasaghi, Z.

A. Moshaverinia, S. Ansari, Z. Movasaghi, R. W. Billington, J. A. Darr, and I. U. Rehman, “Modification of conventional glass-ionomer cements with N-vinylpyrrolidone containing polyacids, nano-hydroxy and fluoroapatite to improve mechanical properties,” Dent. Mater. 24(10), 1381–1390 (2008).
[Crossref] [PubMed]

Muñoz, M.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

Nedbal, L.

O. Samek, A. Jonáš, Z. Pilát, P. Zemánek, L. Nedbal, J. Tříska, P. Kotas, and M. Trtílek, “Raman Microspectroscopy of Individual Algal Cells: Sensing Unsaturation of Storage Lipids in vivo,” Sensors (Basel) 10(9), 8635–8651 (2010).
[Crossref] [PubMed]

Nichi, M.

C. A. Soares, K. Annes, T. R. Dreyer, T. Magrini, M. T. Sonoda, H. da Silva Martinho, M. Nichi, M. E. d’Ávila Assumpção, and M. P. Milazzotto, “Photobiological effect of low-level laser irradiation in bovine embryo production system,” J. Biomed. Opt. 19(3), 035006 (2014).
[Crossref] [PubMed]

Nohalez, A.

C. A. Martinez, A. Nohalez, C. Cuello, J. M. Vazquez, J. Roca, E. A. Martinez, and M. A. Gil, “The use of mineral oil during in vitro maturation, fertilization, and embryo culture does not impair the developmental competence of pig oocytes,” Theriogenology 83(4), 693–702 (2015).
[Crossref] [PubMed]

Ou, D.

L. Xue, P. Sun, D. Ou, P. Chen, M. Chen, and B. Yan, “Diagnosis of pathological minor salivary glands in primary Sjogren’s syndrome by using Raman spectroscopy,” Lasers Med. Sci. 29(2), 723–728 (2014).
[Crossref] [PubMed]

Peng, J.

Q. Zhao, T. Yin, J. Peng, Y. Zou, J. Yang, A. Shen, and J. Hu, “Noninvasive Metabolomic Profiling of Human Embryo Culture Media Using a Simple Spectroscopy Adjunct to Morphology for Embryo Assessment in in Vitro Fertilization (IVF),” Int. J. Mol. Sci. 14(4), 6556–6570 (2013).
[Crossref] [PubMed]

A. G. Shen, J. Peng, Q. H. Zhao, L. Su, X. H. Wang, J. M. Hu, and Q. Yang, “Accurate and noninvasive embryos screening during in vitro fertilization (IVF) assisted by Raman analysis of embryos culture medium,” Laser Phys. Lett. 9(4), 322–328 (2012).
[Crossref]

Pilát, Z.

O. Samek, A. Jonáš, Z. Pilát, P. Zemánek, L. Nedbal, J. Tříska, P. Kotas, and M. Trtílek, “Raman Microspectroscopy of Individual Algal Cells: Sensing Unsaturation of Storage Lipids in vivo,” Sensors (Basel) 10(9), 8635–8651 (2010).
[Crossref] [PubMed]

Ponsart, C.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

Pu, Y.

Y. Zhou, C. H. Liu, Y. Sun, Y. Pu, S. Boydston-White, Y. Liu, and R. R. Alfano, “Human brain cancer studied by resonance Raman spectroscopy,” J. Biomed. Opt. 17(11), 116021 (2012).
[Crossref] [PubMed]

Pudakalakatti, S. M.

S. M. Pudakalakatti, S. Uppangala, F. D’Souza, G. Kalthur, P. Kumar, S. K. Adiga, and H. S. Atreya, “NMR studies of preimplantation embryo metabolism in human assisted reproductive techniques: a new biomarker for assessment of embryo implantation potential,” NMR Biomed. 26(1), 20–27 (2013).
[Crossref] [PubMed]

Rehman, I. U.

A. Moshaverinia, S. Ansari, Z. Movasaghi, R. W. Billington, J. A. Darr, and I. U. Rehman, “Modification of conventional glass-ionomer cements with N-vinylpyrrolidone containing polyacids, nano-hydroxy and fluoroapatite to improve mechanical properties,” Dent. Mater. 24(10), 1381–1390 (2008).
[Crossref] [PubMed]

Roberts, S. A.

D. R. Brison, F. D. Houghton, D. Falconer, S. A. Roberts, J. Hawkhead, P. G. Humpherson, B. A. Lieberman, and H. J. Leese, “Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover,” Hum. Reprod. 19(10), 2319–2324 (2004).
[Crossref] [PubMed]

Roca, J.

C. A. Martinez, A. Nohalez, C. Cuello, J. M. Vazquez, J. Roca, E. A. Martinez, and M. A. Gil, “The use of mineral oil during in vitro maturation, fertilization, and embryo culture does not impair the developmental competence of pig oocytes,” Theriogenology 83(4), 693–702 (2015).
[Crossref] [PubMed]

Rogberg, L.

T. Hardarson, A. Ahlström, L. Rogberg, L. Botros, T. Hillensjö, G. Westlander, D. Sakkas, and M. Wikland, “Non-invasive metabolomic profiling of Day 2 and 5 embryo culture medium: a prospective randomized trial,” Hum. Reprod. 27(1), 89–96 (2012).
[Crossref] [PubMed]

Roos, P.

C. G. Vergouw, L. L. Botros, P. Roos, J. W. Lens, R. Schats, P. G. A. Hompes, D. H. Burns, and C. B. Lambalk, “Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection,” Hum. Reprod. 23(7), 1499–1504 (2008).
[Crossref] [PubMed]

Rosendahl, S. M.

E. Seli, D. Sakkas, R. Scott, S. C. Kwok, S. M. Rosendahl, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 88(5), 1350–1357 (2007).
[Crossref] [PubMed]

Sakkas, D.

T. Hardarson, A. Ahlström, L. Rogberg, L. Botros, T. Hillensjö, G. Westlander, D. Sakkas, and M. Wikland, “Non-invasive metabolomic profiling of Day 2 and 5 embryo culture medium: a prospective randomized trial,” Hum. Reprod. 27(1), 89–96 (2012).
[Crossref] [PubMed]

R. Scott, E. Seli, K. Miller, D. Sakkas, K. Scott, and D. H. Burns, “Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot study,” Fertil. Steril. 90(1), 77–83 (2008).
[Crossref] [PubMed]

E. Seli, L. Botros, D. Sakkas, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 90(6), 2183–2189 (2008).
[Crossref] [PubMed]

E. Seli, D. Sakkas, R. Scott, S. C. Kwok, S. M. Rosendahl, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 88(5), 1350–1357 (2007).
[Crossref] [PubMed]

Samek, O.

O. Samek, A. Jonáš, Z. Pilát, P. Zemánek, L. Nedbal, J. Tříska, P. Kotas, and M. Trtílek, “Raman Microspectroscopy of Individual Algal Cells: Sensing Unsaturation of Storage Lipids in vivo,” Sensors (Basel) 10(9), 8635–8651 (2010).
[Crossref] [PubMed]

Schats, R.

C. G. Vergouw, L. L. Botros, P. Roos, J. W. Lens, R. Schats, P. G. A. Hompes, D. H. Burns, and C. B. Lambalk, “Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection,” Hum. Reprod. 23(7), 1499–1504 (2008).
[Crossref] [PubMed]

Schoolcraft, W. B.

D. K. Gardner, M. Lane, J. Stevens, and W. B. Schoolcraft, “Noninvasive assessment of human embryo nutrient consumption as a measure of developmental potential,” Fertil. Steril. 76(6), 1175–1180 (2001).
[Crossref] [PubMed]

Scott, K.

R. Scott, E. Seli, K. Miller, D. Sakkas, K. Scott, and D. H. Burns, “Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot study,” Fertil. Steril. 90(1), 77–83 (2008).
[Crossref] [PubMed]

Scott, R.

R. Scott, E. Seli, K. Miller, D. Sakkas, K. Scott, and D. H. Burns, “Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot study,” Fertil. Steril. 90(1), 77–83 (2008).
[Crossref] [PubMed]

E. Seli, D. Sakkas, R. Scott, S. C. Kwok, S. M. Rosendahl, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 88(5), 1350–1357 (2007).
[Crossref] [PubMed]

Seli, E.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

E. Seli, L. Botros, D. Sakkas, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 90(6), 2183–2189 (2008).
[Crossref] [PubMed]

R. Scott, E. Seli, K. Miller, D. Sakkas, K. Scott, and D. H. Burns, “Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot study,” Fertil. Steril. 90(1), 77–83 (2008).
[Crossref] [PubMed]

E. Seli, D. Sakkas, R. Scott, S. C. Kwok, S. M. Rosendahl, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 88(5), 1350–1357 (2007).
[Crossref] [PubMed]

Setti, A. S.

S. S. Cortezzi, E. C. Cabral, M. G. Trevisan, C. R. Ferreira, A. S. Setti, D. P. Braga, R. C. Figueira, A. Iaconelli, M. N. Eberlin, and E. Borges., “Prediction of embryo implantation potential by mass spectrometry fingerprinting of the culture medium,” Reproduction 145(5), 453–462 (2013).
[Crossref] [PubMed]

Shen, A.

Q. Zhao, T. Yin, J. Peng, Y. Zou, J. Yang, A. Shen, and J. Hu, “Noninvasive Metabolomic Profiling of Human Embryo Culture Media Using a Simple Spectroscopy Adjunct to Morphology for Embryo Assessment in in Vitro Fertilization (IVF),” Int. J. Mol. Sci. 14(4), 6556–6570 (2013).
[Crossref] [PubMed]

Shen, A. G.

A. G. Shen, J. Peng, Q. H. Zhao, L. Su, X. H. Wang, J. M. Hu, and Q. Yang, “Accurate and noninvasive embryos screening during in vitro fertilization (IVF) assisted by Raman analysis of embryos culture medium,” Laser Phys. Lett. 9(4), 322–328 (2012).
[Crossref]

Shimada, M.

M. Shimada, N. Kawano, and T. Terada, “Delay of nuclear maturation and reduction in developmental competence of pig oocytes after mineral oil overlay of in vitro maturation media,” Reproduction 124(4), 557–564 (2002).
[Crossref] [PubMed]

Soares, C. A.

C. A. Soares, K. Annes, T. R. Dreyer, T. Magrini, M. T. Sonoda, H. da Silva Martinho, M. Nichi, M. E. d’Ávila Assumpção, and M. P. Milazzotto, “Photobiological effect of low-level laser irradiation in bovine embryo production system,” J. Biomed. Opt. 19(3), 035006 (2014).
[Crossref] [PubMed]

Sonoda, M. T.

C. A. Soares, K. Annes, T. R. Dreyer, T. Magrini, M. T. Sonoda, H. da Silva Martinho, M. Nichi, M. E. d’Ávila Assumpção, and M. P. Milazzotto, “Photobiological effect of low-level laser irradiation in bovine embryo production system,” J. Biomed. Opt. 19(3), 035006 (2014).
[Crossref] [PubMed]

Stevens, J.

D. K. Gardner, M. Lane, J. Stevens, and W. B. Schoolcraft, “Noninvasive assessment of human embryo nutrient consumption as a measure of developmental potential,” Fertil. Steril. 76(6), 1175–1180 (2001).
[Crossref] [PubMed]

Su, L.

A. G. Shen, J. Peng, Q. H. Zhao, L. Su, X. H. Wang, J. M. Hu, and Q. Yang, “Accurate and noninvasive embryos screening during in vitro fertilization (IVF) assisted by Raman analysis of embryos culture medium,” Laser Phys. Lett. 9(4), 322–328 (2012).
[Crossref]

Sun, P.

L. Xue, P. Sun, D. Ou, P. Chen, M. Chen, and B. Yan, “Diagnosis of pathological minor salivary glands in primary Sjogren’s syndrome by using Raman spectroscopy,” Lasers Med. Sci. 29(2), 723–728 (2014).
[Crossref] [PubMed]

Sun, Y.

Z. Huang, Y. Sun, J. Wang, S. Du, Y. Li, J. Lin, S. Feng, J. Lei, H. Lin, R. Chen, and H. Zeng, “Rapid and nondestructive method for evaluation of embryo culture media using drop coating deposition Raman spectroscopy,” J. Biomed. Opt. 18(12), 127003 (2013).
[Crossref] [PubMed]

Y. Zhou, C. H. Liu, Y. Sun, Y. Pu, S. Boydston-White, Y. Liu, and R. R. Alfano, “Human brain cancer studied by resonance Raman spectroscopy,” J. Biomed. Opt. 17(11), 116021 (2012).
[Crossref] [PubMed]

Teh, M.

M. S. Bergholt, W. Zheng, K. Lin, K. Y. Ho, M. Teh, K. G. Yeoh, J. B. Yan So, and Z. Huang, “In vivo diagnosis of gastric cancer using Raman endoscopy and ant colony optimization techniques,” Int. J. Cancer 128(11), 2673–2680 (2011).
[Crossref] [PubMed]

Terada, T.

M. Shimada, N. Kawano, and T. Terada, “Delay of nuclear maturation and reduction in developmental competence of pig oocytes after mineral oil overlay of in vitro maturation media,” Reproduction 124(4), 557–564 (2002).
[Crossref] [PubMed]

Thouas, G. A.

Y. S. Lee, G. A. Thouas, and D. K. Gardner, “Developmental kinetics of cleavage stage mouse embryos are related to their subsequent carbohydrate and amino acid utilization at the blastocyst stage,” Hum. Reprod. 30(3), 543–552 (2015).
[Crossref] [PubMed]

Trevisan, M. G.

S. S. Cortezzi, E. C. Cabral, M. G. Trevisan, C. R. Ferreira, A. S. Setti, D. P. Braga, R. C. Figueira, A. Iaconelli, M. N. Eberlin, and E. Borges., “Prediction of embryo implantation potential by mass spectrometry fingerprinting of the culture medium,” Reproduction 145(5), 453–462 (2013).
[Crossref] [PubMed]

Trigal, B.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

Tríska, J.

O. Samek, A. Jonáš, Z. Pilát, P. Zemánek, L. Nedbal, J. Tříska, P. Kotas, and M. Trtílek, “Raman Microspectroscopy of Individual Algal Cells: Sensing Unsaturation of Storage Lipids in vivo,” Sensors (Basel) 10(9), 8635–8651 (2010).
[Crossref] [PubMed]

Trtílek, M.

O. Samek, A. Jonáš, Z. Pilát, P. Zemánek, L. Nedbal, J. Tříska, P. Kotas, and M. Trtílek, “Raman Microspectroscopy of Individual Algal Cells: Sensing Unsaturation of Storage Lipids in vivo,” Sensors (Basel) 10(9), 8635–8651 (2010).
[Crossref] [PubMed]

Uppangala, S.

S. M. Pudakalakatti, S. Uppangala, F. D’Souza, G. Kalthur, P. Kumar, S. K. Adiga, and H. S. Atreya, “NMR studies of preimplantation embryo metabolism in human assisted reproductive techniques: a new biomarker for assessment of embryo implantation potential,” NMR Biomed. 26(1), 20–27 (2013).
[Crossref] [PubMed]

Uuyar, A.

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

Vazquez, J. M.

C. A. Martinez, A. Nohalez, C. Cuello, J. M. Vazquez, J. Roca, E. A. Martinez, and M. A. Gil, “The use of mineral oil during in vitro maturation, fertilization, and embryo culture does not impair the developmental competence of pig oocytes,” Theriogenology 83(4), 693–702 (2015).
[Crossref] [PubMed]

Vergouw, C. G.

C. G. Vergouw, L. L. Botros, P. Roos, J. W. Lens, R. Schats, P. G. A. Hompes, D. H. Burns, and C. B. Lambalk, “Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection,” Hum. Reprod. 23(7), 1499–1504 (2008).
[Crossref] [PubMed]

Wallace, M.

M. Wallace, E. Cottell, J. Cullinane, F. M. McAuliffe, M. Wingfield, and L. Brennan, “(1)H NMR based metabolic profiling of day 2 spent embryo media correlates with implantation potential,” Syst. Biol. Reprod. Med. 60(1), 58–63 (2014).
[Crossref] [PubMed]

Wang, J.

Z. Huang, Y. Sun, J. Wang, S. Du, Y. Li, J. Lin, S. Feng, J. Lei, H. Lin, R. Chen, and H. Zeng, “Rapid and nondestructive method for evaluation of embryo culture media using drop coating deposition Raman spectroscopy,” J. Biomed. Opt. 18(12), 127003 (2013).
[Crossref] [PubMed]

Wang, X. H.

A. G. Shen, J. Peng, Q. H. Zhao, L. Su, X. H. Wang, J. M. Hu, and Q. Yang, “Accurate and noninvasive embryos screening during in vitro fertilization (IVF) assisted by Raman analysis of embryos culture medium,” Laser Phys. Lett. 9(4), 322–328 (2012).
[Crossref]

Westlander, G.

T. Hardarson, A. Ahlström, L. Rogberg, L. Botros, T. Hillensjö, G. Westlander, D. Sakkas, and M. Wikland, “Non-invasive metabolomic profiling of Day 2 and 5 embryo culture medium: a prospective randomized trial,” Hum. Reprod. 27(1), 89–96 (2012).
[Crossref] [PubMed]

Wikland, M.

T. Hardarson, A. Ahlström, L. Rogberg, L. Botros, T. Hillensjö, G. Westlander, D. Sakkas, and M. Wikland, “Non-invasive metabolomic profiling of Day 2 and 5 embryo culture medium: a prospective randomized trial,” Hum. Reprod. 27(1), 89–96 (2012).
[Crossref] [PubMed]

Wingfield, M.

M. Wallace, E. Cottell, J. Cullinane, F. M. McAuliffe, M. Wingfield, and L. Brennan, “(1)H NMR based metabolic profiling of day 2 spent embryo media correlates with implantation potential,” Syst. Biol. Reprod. Med. 60(1), 58–63 (2014).
[Crossref] [PubMed]

Wojdyr, M.

M. Wojdyr, “Fityk: a general-purpose peak fitting program,” J. Appl. Cryst. 43(5), 1126–1128 (2010).
[Crossref]

Xue, L.

L. Xue, P. Sun, D. Ou, P. Chen, M. Chen, and B. Yan, “Diagnosis of pathological minor salivary glands in primary Sjogren’s syndrome by using Raman spectroscopy,” Lasers Med. Sci. 29(2), 723–728 (2014).
[Crossref] [PubMed]

Yan, B.

L. Xue, P. Sun, D. Ou, P. Chen, M. Chen, and B. Yan, “Diagnosis of pathological minor salivary glands in primary Sjogren’s syndrome by using Raman spectroscopy,” Lasers Med. Sci. 29(2), 723–728 (2014).
[Crossref] [PubMed]

Yan So, J. B.

M. S. Bergholt, W. Zheng, K. Lin, K. Y. Ho, M. Teh, K. G. Yeoh, J. B. Yan So, and Z. Huang, “In vivo diagnosis of gastric cancer using Raman endoscopy and ant colony optimization techniques,” Int. J. Cancer 128(11), 2673–2680 (2011).
[Crossref] [PubMed]

Yang, J.

Q. Zhao, T. Yin, J. Peng, Y. Zou, J. Yang, A. Shen, and J. Hu, “Noninvasive Metabolomic Profiling of Human Embryo Culture Media Using a Simple Spectroscopy Adjunct to Morphology for Embryo Assessment in in Vitro Fertilization (IVF),” Int. J. Mol. Sci. 14(4), 6556–6570 (2013).
[Crossref] [PubMed]

Yang, Q.

A. G. Shen, J. Peng, Q. H. Zhao, L. Su, X. H. Wang, J. M. Hu, and Q. Yang, “Accurate and noninvasive embryos screening during in vitro fertilization (IVF) assisted by Raman analysis of embryos culture medium,” Laser Phys. Lett. 9(4), 322–328 (2012).
[Crossref]

Yeoh, K. G.

M. S. Bergholt, W. Zheng, K. Lin, K. Y. Ho, M. Teh, K. G. Yeoh, J. B. Yan So, and Z. Huang, “In vivo diagnosis of gastric cancer using Raman endoscopy and ant colony optimization techniques,” Int. J. Cancer 128(11), 2673–2680 (2011).
[Crossref] [PubMed]

Yin, T.

Q. Zhao, T. Yin, J. Peng, Y. Zou, J. Yang, A. Shen, and J. Hu, “Noninvasive Metabolomic Profiling of Human Embryo Culture Media Using a Simple Spectroscopy Adjunct to Morphology for Embryo Assessment in in Vitro Fertilization (IVF),” Int. J. Mol. Sci. 14(4), 6556–6570 (2013).
[Crossref] [PubMed]

Zemánek, P.

O. Samek, A. Jonáš, Z. Pilát, P. Zemánek, L. Nedbal, J. Tříska, P. Kotas, and M. Trtílek, “Raman Microspectroscopy of Individual Algal Cells: Sensing Unsaturation of Storage Lipids in vivo,” Sensors (Basel) 10(9), 8635–8651 (2010).
[Crossref] [PubMed]

Zeng, H.

Z. Huang, Y. Sun, J. Wang, S. Du, Y. Li, J. Lin, S. Feng, J. Lei, H. Lin, R. Chen, and H. Zeng, “Rapid and nondestructive method for evaluation of embryo culture media using drop coating deposition Raman spectroscopy,” J. Biomed. Opt. 18(12), 127003 (2013).
[Crossref] [PubMed]

Zhao, Q.

Q. Zhao, T. Yin, J. Peng, Y. Zou, J. Yang, A. Shen, and J. Hu, “Noninvasive Metabolomic Profiling of Human Embryo Culture Media Using a Simple Spectroscopy Adjunct to Morphology for Embryo Assessment in in Vitro Fertilization (IVF),” Int. J. Mol. Sci. 14(4), 6556–6570 (2013).
[Crossref] [PubMed]

Zhao, Q. H.

A. G. Shen, J. Peng, Q. H. Zhao, L. Su, X. H. Wang, J. M. Hu, and Q. Yang, “Accurate and noninvasive embryos screening during in vitro fertilization (IVF) assisted by Raman analysis of embryos culture medium,” Laser Phys. Lett. 9(4), 322–328 (2012).
[Crossref]

Zheng, W.

M. S. Bergholt, W. Zheng, K. Lin, K. Y. Ho, M. Teh, K. G. Yeoh, J. B. Yan So, and Z. Huang, “In vivo diagnosis of gastric cancer using Raman endoscopy and ant colony optimization techniques,” Int. J. Cancer 128(11), 2673–2680 (2011).
[Crossref] [PubMed]

Zhou, Y.

Y. Zhou, C. H. Liu, Y. Sun, Y. Pu, S. Boydston-White, Y. Liu, and R. R. Alfano, “Human brain cancer studied by resonance Raman spectroscopy,” J. Biomed. Opt. 17(11), 116021 (2012).
[Crossref] [PubMed]

Zou, Y.

Q. Zhao, T. Yin, J. Peng, Y. Zou, J. Yang, A. Shen, and J. Hu, “Noninvasive Metabolomic Profiling of Human Embryo Culture Media Using a Simple Spectroscopy Adjunct to Morphology for Embryo Assessment in in Vitro Fertilization (IVF),” Int. J. Mol. Sci. 14(4), 6556–6570 (2013).
[Crossref] [PubMed]

Zscherp, C.

A. Barth and C. Zscherp, “What vibrations tell us about proteins,” Q. Rev. Biophys. 35(4), 369–430 (2002).
[Crossref] [PubMed]

Dent. Mater. (1)

A. Moshaverinia, S. Ansari, Z. Movasaghi, R. W. Billington, J. A. Darr, and I. U. Rehman, “Modification of conventional glass-ionomer cements with N-vinylpyrrolidone containing polyacids, nano-hydroxy and fluoroapatite to improve mechanical properties,” Dent. Mater. 24(10), 1381–1390 (2008).
[Crossref] [PubMed]

Fertil. Steril. (5)

E. Seli, L. Botros, D. Sakkas, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 90(6), 2183–2189 (2008).
[Crossref] [PubMed]

J. Herrero and M. Meseguer, “Selection of high potential embryos using time-lapse imaging: the era of morphokinetics,” Fertil. Steril. 99(4), 1030–1034 (2013).
[Crossref] [PubMed]

D. K. Gardner, M. Lane, J. Stevens, and W. B. Schoolcraft, “Noninvasive assessment of human embryo nutrient consumption as a measure of developmental potential,” Fertil. Steril. 76(6), 1175–1180 (2001).
[Crossref] [PubMed]

E. Seli, D. Sakkas, R. Scott, S. C. Kwok, S. M. Rosendahl, and D. H. Burns, “Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization,” Fertil. Steril. 88(5), 1350–1357 (2007).
[Crossref] [PubMed]

R. Scott, E. Seli, K. Miller, D. Sakkas, K. Scott, and D. H. Burns, “Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot study,” Fertil. Steril. 90(1), 77–83 (2008).
[Crossref] [PubMed]

Hum. Reprod. (4)

T. Hardarson, A. Ahlström, L. Rogberg, L. Botros, T. Hillensjö, G. Westlander, D. Sakkas, and M. Wikland, “Non-invasive metabolomic profiling of Day 2 and 5 embryo culture medium: a prospective randomized trial,” Hum. Reprod. 27(1), 89–96 (2012).
[Crossref] [PubMed]

Y. S. Lee, G. A. Thouas, and D. K. Gardner, “Developmental kinetics of cleavage stage mouse embryos are related to their subsequent carbohydrate and amino acid utilization at the blastocyst stage,” Hum. Reprod. 30(3), 543–552 (2015).
[Crossref] [PubMed]

D. R. Brison, F. D. Houghton, D. Falconer, S. A. Roberts, J. Hawkhead, P. G. Humpherson, B. A. Lieberman, and H. J. Leese, “Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover,” Hum. Reprod. 19(10), 2319–2324 (2004).
[Crossref] [PubMed]

C. G. Vergouw, L. L. Botros, P. Roos, J. W. Lens, R. Schats, P. G. A. Hompes, D. H. Burns, and C. B. Lambalk, “Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection,” Hum. Reprod. 23(7), 1499–1504 (2008).
[Crossref] [PubMed]

Int. J. Cancer (1)

M. S. Bergholt, W. Zheng, K. Lin, K. Y. Ho, M. Teh, K. G. Yeoh, J. B. Yan So, and Z. Huang, “In vivo diagnosis of gastric cancer using Raman endoscopy and ant colony optimization techniques,” Int. J. Cancer 128(11), 2673–2680 (2011).
[Crossref] [PubMed]

Int. J. Mol. Sci. (1)

Q. Zhao, T. Yin, J. Peng, Y. Zou, J. Yang, A. Shen, and J. Hu, “Noninvasive Metabolomic Profiling of Human Embryo Culture Media Using a Simple Spectroscopy Adjunct to Morphology for Embryo Assessment in in Vitro Fertilization (IVF),” Int. J. Mol. Sci. 14(4), 6556–6570 (2013).
[Crossref] [PubMed]

J. Appl. Cryst. (1)

M. Wojdyr, “Fityk: a general-purpose peak fitting program,” J. Appl. Cryst. 43(5), 1126–1128 (2010).
[Crossref]

J. Biomed. Opt. (3)

Y. Zhou, C. H. Liu, Y. Sun, Y. Pu, S. Boydston-White, Y. Liu, and R. R. Alfano, “Human brain cancer studied by resonance Raman spectroscopy,” J. Biomed. Opt. 17(11), 116021 (2012).
[Crossref] [PubMed]

C. A. Soares, K. Annes, T. R. Dreyer, T. Magrini, M. T. Sonoda, H. da Silva Martinho, M. Nichi, M. E. d’Ávila Assumpção, and M. P. Milazzotto, “Photobiological effect of low-level laser irradiation in bovine embryo production system,” J. Biomed. Opt. 19(3), 035006 (2014).
[Crossref] [PubMed]

Z. Huang, Y. Sun, J. Wang, S. Du, Y. Li, J. Lin, S. Feng, J. Lei, H. Lin, R. Chen, and H. Zeng, “Rapid and nondestructive method for evaluation of embryo culture media using drop coating deposition Raman spectroscopy,” J. Biomed. Opt. 18(12), 127003 (2013).
[Crossref] [PubMed]

J. Cell. Mol. Med. (1)

S. Cinta Pinzaru, A. Falamas, and C. A. Dehelean, “Molecular conformation changes along the malignancy revealed by optical nanosensors,” J. Cell. Mol. Med. 17(2), 277–286 (2013).
[Crossref] [PubMed]

J. Dairy Sci. (1)

M. Muñoz, A. Uuyar, E. Correia, C. Diez, A. Fernandez-gonzales, J. N. Caamaño, D. Martinez-bello, B. Trigal, P. Humblot, C. Ponsart, C. Guyader-joly, S. Carrocera, D. Martin, B. Marquant Le Guienne, E. Seli, and E. Gomez, “Metabolomic Prediction of Pregnancy Viability in Superovulated Cattle Embryos and Recipients with Fourier Transform Infrared Spectroscopy,” J. Dairy Sci. 97(9), 1–8 (2014).

J. Exp. Zool. (1)

D. K. Gardner and H. J. Leese, “Assessment of embryo viability prior to transfer by the noninvasive measurement of glucose uptake,” J. Exp. Zool. 242(1), 103–105 (1987).
[Crossref] [PubMed]

Laser Phys. Lett. (1)

A. G. Shen, J. Peng, Q. H. Zhao, L. Su, X. H. Wang, J. M. Hu, and Q. Yang, “Accurate and noninvasive embryos screening during in vitro fertilization (IVF) assisted by Raman analysis of embryos culture medium,” Laser Phys. Lett. 9(4), 322–328 (2012).
[Crossref]

Lasers Med. Sci. (1)

L. Xue, P. Sun, D. Ou, P. Chen, M. Chen, and B. Yan, “Diagnosis of pathological minor salivary glands in primary Sjogren’s syndrome by using Raman spectroscopy,” Lasers Med. Sci. 29(2), 723–728 (2014).
[Crossref] [PubMed]

NMR Biomed. (1)

S. M. Pudakalakatti, S. Uppangala, F. D’Souza, G. Kalthur, P. Kumar, S. K. Adiga, and H. S. Atreya, “NMR studies of preimplantation embryo metabolism in human assisted reproductive techniques: a new biomarker for assessment of embryo implantation potential,” NMR Biomed. 26(1), 20–27 (2013).
[Crossref] [PubMed]

Q. Rev. Biophys. (1)

A. Barth and C. Zscherp, “What vibrations tell us about proteins,” Q. Rev. Biophys. 35(4), 369–430 (2002).
[Crossref] [PubMed]

Reproduction (2)

S. S. Cortezzi, E. C. Cabral, M. G. Trevisan, C. R. Ferreira, A. S. Setti, D. P. Braga, R. C. Figueira, A. Iaconelli, M. N. Eberlin, and E. Borges., “Prediction of embryo implantation potential by mass spectrometry fingerprinting of the culture medium,” Reproduction 145(5), 453–462 (2013).
[Crossref] [PubMed]

M. Shimada, N. Kawano, and T. Terada, “Delay of nuclear maturation and reduction in developmental competence of pig oocytes after mineral oil overlay of in vitro maturation media,” Reproduction 124(4), 557–564 (2002).
[Crossref] [PubMed]

Sensors (Basel) (1)

O. Samek, A. Jonáš, Z. Pilát, P. Zemánek, L. Nedbal, J. Tříska, P. Kotas, and M. Trtílek, “Raman Microspectroscopy of Individual Algal Cells: Sensing Unsaturation of Storage Lipids in vivo,” Sensors (Basel) 10(9), 8635–8651 (2010).
[Crossref] [PubMed]

Syst. Biol. Reprod. Med. (1)

M. Wallace, E. Cottell, J. Cullinane, F. M. McAuliffe, M. Wingfield, and L. Brennan, “(1)H NMR based metabolic profiling of day 2 spent embryo media correlates with implantation potential,” Syst. Biol. Reprod. Med. 60(1), 58–63 (2014).
[Crossref] [PubMed]

Theriogenology (2)

A. S. Lopes, T. Greve, and H. Callesen, “Quantification of embryo quality by respirometry,” Theriogenology 67(1), 21–31 (2007).
[Crossref] [PubMed]

C. A. Martinez, A. Nohalez, C. Cuello, J. M. Vazquez, J. Roca, E. A. Martinez, and M. A. Gil, “The use of mineral oil during in vitro maturation, fertilization, and embryo culture does not impair the developmental competence of pig oocytes,” Theriogenology 83(4), 693–702 (2015).
[Crossref] [PubMed]

Other (1)

P. B. D. Gonçalves, M. A. L. Oliveira, A. Mezzalira, M. M. Montagner, J. A. Visitin, and L. F. S. Costa, Biotécnicas aplicadas à reprodução animal (Roca, 2008).

Cited By

OSA participates in Crossref's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (6)

Fig. 1
Fig. 1 Schematic diagram of the proposed experimental model. A) culture medium droplets covered with mineral oil on Petri dish in the micro-Raman system; B) incidence of the laser beam on the sample with the spectra acquisition.
Fig. 2
Fig. 2 Oil-culture interface identification in the droplet. The two highlighted regions corresponding to the spectrum of the surface of the mineral oil (0 µm in the z-axis) and the interface between oil and culture medium (18 µm z-axis) are shown.
Fig. 3
Fig. 3 Average Raman spectra of the following groups: culture media without embryos (KSOM and SOFaa), with embryos (SOFaaE), mineral oil and Petri dish in the 500-3200 cm−1 region.
Fig. 4
Fig. 4 Raman spectra of culture medium with embryos (SOFaaE) with their corresponding vibrational bands in the 500 to 3200 cm−1 region.
Fig. 5
Fig. 5 Principal Component Analysis (PCA) of the Raman spectra of the culture media without embryos (KSOM and SOFaa) and with embryos (SOFaaE) in the Raman bands from 500 to 1800 cm−1 (A) and from 1800 to 3200 cm−1 (B).
Fig. 6
Fig. 6 Loading plot analysis of the Raman spectra of the culture media without embryos (KSOM and SOFaa) and with embryos (SOFaaE) in the Raman bands from 500 to 1800 cm−1 (A) and from 1800 to 3200 cm−1 (B).

Tables (1)

Tables Icon

Table 1 Raman bands assignments of the culture medium with embryos (SOFaaE).

Metrics