Abstract

The rupture of thin-cap fibroatheroma accounts for most acute coronary events. Optical Coherence Tomography (OCT) allows quantification of fibrous cap (FC) thickness in vivo. Conventional manual analysis, by visually determining the thinnest part of the FC is subject to inter-observer variability and does not capture the 3-D morphology of the FC. We propose and validate a computer-aided method that allows volumetric analysis of FC. The radial FC boundary is semi-automatically segmented using a dynamic programming algorithm. The thickness at every point of the FC boundary, along with 3-D morphology of the FC, can be quantified. The method was validated against three experienced OCT image analysts in 14 lipid-rich lesions. The proposed method may advance our understanding of the mechanisms behind plaque rupture and improve disease management.

© 2012 OSA

Full Article  |  PDF Article

References

  • View by:
  • |
  • |
  • |

  1. V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
    [CrossRef] [PubMed]
  2. E. Falk, “Plaque rupture with severe pre-existing stenosis precipitating coronary thrombosis. Characteristics of coronary atherosclerotic plaques underlying fatal occlusive thrombi,” Br. Heart J.50(2), 127–134 (1983).
    [CrossRef] [PubMed]
  3. R. Virmani, A. P. Burke, F. D. Kolodgie, and A. Farb, “Vulnerable plaque: the pathology of unstable coronary lesions,” J. Interv. Cardiol.15(6), 439–446 (2002).
    [CrossRef] [PubMed]
  4. R. Virmani, F. D. Kolodgie, A. P. Burke, A. Farb, and S. M. Schwartz, “Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions,” Arterioscler. Thromb. Vasc. Biol.20(5), 1262–1275 (2000).
    [CrossRef] [PubMed]
  5. A. P. Burke, A. Farb, G. T. Malcom, Y. H. Liang, J. Smialek, and R. Virmani, “Coronary risk factors and plaque morphology in men with coronary disease who died suddenly,” N. Engl. J. Med.336(18), 1276–1282 (1997).
    [CrossRef] [PubMed]
  6. H. G. Bezerra, M. A. Costa, G. Guagliumi, A. M. Rollins, and D. I. Simon, “Intracoronary optical coherence tomography: a comprehensive review clinical and research applications,” JACC Cardiovasc. Interv.2(11), 1035–1046 (2009).
    [CrossRef] [PubMed]
  7. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
    [CrossRef] [PubMed]
  8. I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
    [CrossRef] [PubMed]
  9. T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
    [CrossRef] [PubMed]
  10. K. Fujii, M. Masutani, T. Okumura, D. Kawasaki, T. Akagami, A. Ezumi, T. Sakoda, T. Masuyama, and M. Ohyanagi, “Frequency and predictor of coronary thin-cap fibroatheroma in patients with acute myocardial infarction and stable angina pectoris a 3-vessel optical coherence tomography study,” J. Am. Coll. Cardiol.52(9), 787–788 (2008).
    [CrossRef] [PubMed]
  11. Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
    [CrossRef] [PubMed]
  12. M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
    [CrossRef] [PubMed]
  13. T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
    [CrossRef] [PubMed]
  14. S. Rathore, M. Terashima, H. Matsuo, Y. Kinoshita, M. Kimura, E. Tsuchikane, K. Nasu, M. Ehara, Y. Asakura, O. Katoh, and T. Suzuki, “In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study,” Coron. Artery Dis.22(1), 64–72 (2011).
    [CrossRef] [PubMed]
  15. S. Takarada, T. Imanishi, T. Kubo, T. Tanimoto, H. Kitabata, N. Nakamura, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Effect of statin therapy on coronary fibrous-cap thickness in patients with acute coronary syndrome: assessment by optical coherence tomography study,” Atherosclerosis202(2), 491–497 (2009).
    [CrossRef] [PubMed]
  16. A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
    [CrossRef] [PubMed]
  17. T. Yonetsu, T. Kakuta, T. Lee, K. Takahashi, N. Kawaguchi, G. Yamamoto, K. Koura, K. Hishikari, Y. Iesaka, H. Fujiwara, and M. Isobe, “In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography,” Eur. Heart J.32(10), 1251–1259 (2011).
    [CrossRef] [PubMed]
  18. T. Kume, T. Akasaka, T. Kawamoto, H. Okura, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, and K. Yoshida, “Measurement of the thickness of the fibrous cap by optical coherence tomography,” Am. Heart J.152(4), 755.e1–e755.e4 (2006).
    [CrossRef] [PubMed]
  19. H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, “Characterization of human atherosclerosis by optical coherence tomography,” Circulation106(13), 1640–1645 (2002).
    [CrossRef] [PubMed]
  20. O. C. Raffel, F. M. Merchant, G. J. Tearney, S. Chia, D. D. Gauthier, E. Pomerantsev, K. Mizuno, B. E. Bouma, and I.-K. Jang, “In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography,” Eur. Heart J.29(14), 1721–1728 (2008).
    [CrossRef] [PubMed]
  21. T. H. Cormen, C. E. Leiserson, R. L. Rivest, and C. Stein, Introduction to Algorithms (MIT Press, 2001).
  22. G. van Soest, J. G. Bosch, and A. F. W. van der Steen, “Azimuthal registration of image sequences affected by nonuniform rotation distortion,” IEEE Trans. Inf. Technol. Biomed.12(3), 348–355 (2008).
    [CrossRef] [PubMed]
  23. Z. Wang, H. Kyono, H. Bezerra, D. Wilson, M. Costa, and A. Rollins, “Automatic segmentation of intravascular optical coherence tomography images for facilitating quantitative diagnosis of atherosclerosis,” Proc. SPIE7889, 78890N (2011).
    [CrossRef]
  24. G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
    [CrossRef] [PubMed]
  25. C. Xu, J. M. Schmitt, S. G. Carlier, and R. Virmani, “Characterization of atherosclerosis plaques by measuring both backscattering and attenuation coefficients in optical coherence tomography,” J. Biomed. Opt.13(3), 034003–034008 (2008).
    [CrossRef] [PubMed]
  26. M. S. Nguyen, O. Salvado, D. Roy, G. Steyer, M. E. Stone, R. D. Hoffman, and D. L. Wilson, “Ex vivo characterization of human atherosclerotic iliac plaque components using cryo-imaging,” J. Microsc.232(3), 432–441 (2008).
    [CrossRef] [PubMed]
  27. C. L. Lendon, M. J. Davies, G. V. R. Born, and P. D. Richardson, “Atherosclerotic plaque caps are locally weakened when macrophages density is increased,” Atherosclerosis87(1), 87–90 (1991).
    [CrossRef] [PubMed]
  28. J. Ohayon, G. Finet, A. M. Gharib, D. A. Herzka, P. Tracqui, J. Heroux, G. Rioufol, M. S. Kotys, A. Elagha, and R. I. Pettigrew, “Necrotic core thickness and positive arterial remodeling index: emergent biomechanical factors for evaluating the risk of plaque rupture,” Am. J. Physiol. Heart Circ. Physiol.295(2), H717–H727 (2008).
    [CrossRef] [PubMed]
  29. Y. Vengrenyuk, S. Carlier, S. Xanthos, L. Cardoso, P. Ganatos, R. Virmani, S. Einav, L. Gilchrist, and S. Weinbaum, “A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps,” Proc. Natl. Acad. Sci. U.S.A.103(40), 14678–14683 (2006).
    [CrossRef] [PubMed]

2011

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

S. Rathore, M. Terashima, H. Matsuo, Y. Kinoshita, M. Kimura, E. Tsuchikane, K. Nasu, M. Ehara, Y. Asakura, O. Katoh, and T. Suzuki, “In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study,” Coron. Artery Dis.22(1), 64–72 (2011).
[CrossRef] [PubMed]

T. Yonetsu, T. Kakuta, T. Lee, K. Takahashi, N. Kawaguchi, G. Yamamoto, K. Koura, K. Hishikari, Y. Iesaka, H. Fujiwara, and M. Isobe, “In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography,” Eur. Heart J.32(10), 1251–1259 (2011).
[CrossRef] [PubMed]

Z. Wang, H. Kyono, H. Bezerra, D. Wilson, M. Costa, and A. Rollins, “Automatic segmentation of intravascular optical coherence tomography images for facilitating quantitative diagnosis of atherosclerosis,” Proc. SPIE7889, 78890N (2011).
[CrossRef]

2010

G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

2009

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

S. Takarada, T. Imanishi, T. Kubo, T. Tanimoto, H. Kitabata, N. Nakamura, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Effect of statin therapy on coronary fibrous-cap thickness in patients with acute coronary syndrome: assessment by optical coherence tomography study,” Atherosclerosis202(2), 491–497 (2009).
[CrossRef] [PubMed]

H. G. Bezerra, M. A. Costa, G. Guagliumi, A. M. Rollins, and D. I. Simon, “Intracoronary optical coherence tomography: a comprehensive review clinical and research applications,” JACC Cardiovasc. Interv.2(11), 1035–1046 (2009).
[CrossRef] [PubMed]

2008

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

K. Fujii, M. Masutani, T. Okumura, D. Kawasaki, T. Akagami, A. Ezumi, T. Sakoda, T. Masuyama, and M. Ohyanagi, “Frequency and predictor of coronary thin-cap fibroatheroma in patients with acute myocardial infarction and stable angina pectoris a 3-vessel optical coherence tomography study,” J. Am. Coll. Cardiol.52(9), 787–788 (2008).
[CrossRef] [PubMed]

C. Xu, J. M. Schmitt, S. G. Carlier, and R. Virmani, “Characterization of atherosclerosis plaques by measuring both backscattering and attenuation coefficients in optical coherence tomography,” J. Biomed. Opt.13(3), 034003–034008 (2008).
[CrossRef] [PubMed]

M. S. Nguyen, O. Salvado, D. Roy, G. Steyer, M. E. Stone, R. D. Hoffman, and D. L. Wilson, “Ex vivo characterization of human atherosclerotic iliac plaque components using cryo-imaging,” J. Microsc.232(3), 432–441 (2008).
[CrossRef] [PubMed]

O. C. Raffel, F. M. Merchant, G. J. Tearney, S. Chia, D. D. Gauthier, E. Pomerantsev, K. Mizuno, B. E. Bouma, and I.-K. Jang, “In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography,” Eur. Heart J.29(14), 1721–1728 (2008).
[CrossRef] [PubMed]

G. van Soest, J. G. Bosch, and A. F. W. van der Steen, “Azimuthal registration of image sequences affected by nonuniform rotation distortion,” IEEE Trans. Inf. Technol. Biomed.12(3), 348–355 (2008).
[CrossRef] [PubMed]

J. Ohayon, G. Finet, A. M. Gharib, D. A. Herzka, P. Tracqui, J. Heroux, G. Rioufol, M. S. Kotys, A. Elagha, and R. I. Pettigrew, “Necrotic core thickness and positive arterial remodeling index: emergent biomechanical factors for evaluating the risk of plaque rupture,” Am. J. Physiol. Heart Circ. Physiol.295(2), H717–H727 (2008).
[CrossRef] [PubMed]

2007

T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
[CrossRef] [PubMed]

2006

T. Kume, T. Akasaka, T. Kawamoto, H. Okura, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, and K. Yoshida, “Measurement of the thickness of the fibrous cap by optical coherence tomography,” Am. Heart J.152(4), 755.e1–e755.e4 (2006).
[CrossRef] [PubMed]

Y. Vengrenyuk, S. Carlier, S. Xanthos, L. Cardoso, P. Ganatos, R. Virmani, S. Einav, L. Gilchrist, and S. Weinbaum, “A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps,” Proc. Natl. Acad. Sci. U.S.A.103(40), 14678–14683 (2006).
[CrossRef] [PubMed]

2002

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, “Characterization of human atherosclerosis by optical coherence tomography,” Circulation106(13), 1640–1645 (2002).
[CrossRef] [PubMed]

I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
[CrossRef] [PubMed]

R. Virmani, A. P. Burke, F. D. Kolodgie, and A. Farb, “Vulnerable plaque: the pathology of unstable coronary lesions,” J. Interv. Cardiol.15(6), 439–446 (2002).
[CrossRef] [PubMed]

2000

R. Virmani, F. D. Kolodgie, A. P. Burke, A. Farb, and S. M. Schwartz, “Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions,” Arterioscler. Thromb. Vasc. Biol.20(5), 1262–1275 (2000).
[CrossRef] [PubMed]

1997

A. P. Burke, A. Farb, G. T. Malcom, Y. H. Liang, J. Smialek, and R. Virmani, “Coronary risk factors and plaque morphology in men with coronary disease who died suddenly,” N. Engl. J. Med.336(18), 1276–1282 (1997).
[CrossRef] [PubMed]

1991

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

C. L. Lendon, M. J. Davies, G. V. R. Born, and P. D. Richardson, “Atherosclerotic plaque caps are locally weakened when macrophages density is increased,” Atherosclerosis87(1), 87–90 (1991).
[CrossRef] [PubMed]

1983

E. Falk, “Plaque rupture with severe pre-existing stenosis precipitating coronary thrombosis. Characteristics of coronary atherosclerotic plaques underlying fatal occlusive thrombi,” Br. Heart J.50(2), 127–134 (1983).
[CrossRef] [PubMed]

Adams, R. J.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Akagami, T.

K. Fujii, M. Masutani, T. Okumura, D. Kawasaki, T. Akagami, A. Ezumi, T. Sakoda, T. Masuyama, and M. Ohyanagi, “Frequency and predictor of coronary thin-cap fibroatheroma in patients with acute myocardial infarction and stable angina pectoris a 3-vessel optical coherence tomography study,” J. Am. Coll. Cardiol.52(9), 787–788 (2008).
[CrossRef] [PubMed]

Akasaka, T.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

S. Takarada, T. Imanishi, T. Kubo, T. Tanimoto, H. Kitabata, N. Nakamura, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Effect of statin therapy on coronary fibrous-cap thickness in patients with acute coronary syndrome: assessment by optical coherence tomography study,” Atherosclerosis202(2), 491–497 (2009).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
[CrossRef] [PubMed]

T. Kume, T. Akasaka, T. Kawamoto, H. Okura, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, and K. Yoshida, “Measurement of the thickness of the fibrous cap by optical coherence tomography,” Am. Heart J.152(4), 755.e1–e755.e4 (2006).
[CrossRef] [PubMed]

Aretz, H. T.

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, “Characterization of human atherosclerosis by optical coherence tomography,” Circulation106(13), 1640–1645 (2002).
[CrossRef] [PubMed]

I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
[CrossRef] [PubMed]

Arita, Y.

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

Asakura, Y.

S. Rathore, M. Terashima, H. Matsuo, Y. Kinoshita, M. Kimura, E. Tsuchikane, K. Nasu, M. Ehara, Y. Asakura, O. Katoh, and T. Suzuki, “In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study,” Coron. Artery Dis.22(1), 64–72 (2011).
[CrossRef] [PubMed]

Berry, J. D.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Bezerra, H.

Z. Wang, H. Kyono, H. Bezerra, D. Wilson, M. Costa, and A. Rollins, “Automatic segmentation of intravascular optical coherence tomography images for facilitating quantitative diagnosis of atherosclerosis,” Proc. SPIE7889, 78890N (2011).
[CrossRef]

Bezerra, H. G.

H. G. Bezerra, M. A. Costa, G. Guagliumi, A. M. Rollins, and D. I. Simon, “Intracoronary optical coherence tomography: a comprehensive review clinical and research applications,” JACC Cardiovasc. Interv.2(11), 1035–1046 (2009).
[CrossRef] [PubMed]

Born, G. V. R.

C. L. Lendon, M. J. Davies, G. V. R. Born, and P. D. Richardson, “Atherosclerotic plaque caps are locally weakened when macrophages density is increased,” Atherosclerosis87(1), 87–90 (1991).
[CrossRef] [PubMed]

Bosch, J. G.

G. van Soest, J. G. Bosch, and A. F. W. van der Steen, “Azimuthal registration of image sequences affected by nonuniform rotation distortion,” IEEE Trans. Inf. Technol. Biomed.12(3), 348–355 (2008).
[CrossRef] [PubMed]

Bouma, B. E.

G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
[CrossRef] [PubMed]

O. C. Raffel, F. M. Merchant, G. J. Tearney, S. Chia, D. D. Gauthier, E. Pomerantsev, K. Mizuno, B. E. Bouma, and I.-K. Jang, “In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography,” Eur. Heart J.29(14), 1721–1728 (2008).
[CrossRef] [PubMed]

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, “Characterization of human atherosclerosis by optical coherence tomography,” Circulation106(13), 1640–1645 (2002).
[CrossRef] [PubMed]

I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
[CrossRef] [PubMed]

Brown, T. M.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Burke, A. P.

R. Virmani, A. P. Burke, F. D. Kolodgie, and A. Farb, “Vulnerable plaque: the pathology of unstable coronary lesions,” J. Interv. Cardiol.15(6), 439–446 (2002).
[CrossRef] [PubMed]

R. Virmani, F. D. Kolodgie, A. P. Burke, A. Farb, and S. M. Schwartz, “Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions,” Arterioscler. Thromb. Vasc. Biol.20(5), 1262–1275 (2000).
[CrossRef] [PubMed]

A. P. Burke, A. Farb, G. T. Malcom, Y. H. Liang, J. Smialek, and R. Virmani, “Coronary risk factors and plaque morphology in men with coronary disease who died suddenly,” N. Engl. J. Med.336(18), 1276–1282 (1997).
[CrossRef] [PubMed]

Cardoso, L.

Y. Vengrenyuk, S. Carlier, S. Xanthos, L. Cardoso, P. Ganatos, R. Virmani, S. Einav, L. Gilchrist, and S. Weinbaum, “A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps,” Proc. Natl. Acad. Sci. U.S.A.103(40), 14678–14683 (2006).
[CrossRef] [PubMed]

Carlier, S.

Y. Vengrenyuk, S. Carlier, S. Xanthos, L. Cardoso, P. Ganatos, R. Virmani, S. Einav, L. Gilchrist, and S. Weinbaum, “A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps,” Proc. Natl. Acad. Sci. U.S.A.103(40), 14678–14683 (2006).
[CrossRef] [PubMed]

Carlier, S. G.

C. Xu, J. M. Schmitt, S. G. Carlier, and R. Virmani, “Characterization of atherosclerosis plaques by measuring both backscattering and attenuation coefficients in optical coherence tomography,” J. Biomed. Opt.13(3), 034003–034008 (2008).
[CrossRef] [PubMed]

Carnethon, M. R.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Chang, W.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Chia, S.

O. C. Raffel, F. M. Merchant, G. J. Tearney, S. Chia, D. D. Gauthier, E. Pomerantsev, K. Mizuno, B. E. Bouma, and I.-K. Jang, “In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography,” Eur. Heart J.29(14), 1721–1728 (2008).
[CrossRef] [PubMed]

Choi, K.-B.

I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
[CrossRef] [PubMed]

Costa, M.

Z. Wang, H. Kyono, H. Bezerra, D. Wilson, M. Costa, and A. Rollins, “Automatic segmentation of intravascular optical coherence tomography images for facilitating quantitative diagnosis of atherosclerosis,” Proc. SPIE7889, 78890N (2011).
[CrossRef]

Costa, M. A.

H. G. Bezerra, M. A. Costa, G. Guagliumi, A. M. Rollins, and D. I. Simon, “Intracoronary optical coherence tomography: a comprehensive review clinical and research applications,” JACC Cardiovasc. Interv.2(11), 1035–1046 (2009).
[CrossRef] [PubMed]

Dai, S.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Davies, M. J.

C. L. Lendon, M. J. Davies, G. V. R. Born, and P. D. Richardson, “Atherosclerotic plaque caps are locally weakened when macrophages density is increased,” Atherosclerosis87(1), 87–90 (1991).
[CrossRef] [PubMed]

de Simone, G.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Ehara, M.

S. Rathore, M. Terashima, H. Matsuo, Y. Kinoshita, M. Kimura, E. Tsuchikane, K. Nasu, M. Ehara, Y. Asakura, O. Katoh, and T. Suzuki, “In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study,” Coron. Artery Dis.22(1), 64–72 (2011).
[CrossRef] [PubMed]

Einav, S.

Y. Vengrenyuk, S. Carlier, S. Xanthos, L. Cardoso, P. Ganatos, R. Virmani, S. Einav, L. Gilchrist, and S. Weinbaum, “A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps,” Proc. Natl. Acad. Sci. U.S.A.103(40), 14678–14683 (2006).
[CrossRef] [PubMed]

Elagha, A.

J. Ohayon, G. Finet, A. M. Gharib, D. A. Herzka, P. Tracqui, J. Heroux, G. Rioufol, M. S. Kotys, A. Elagha, and R. I. Pettigrew, “Necrotic core thickness and positive arterial remodeling index: emergent biomechanical factors for evaluating the risk of plaque rupture,” Am. J. Physiol. Heart Circ. Physiol.295(2), H717–H727 (2008).
[CrossRef] [PubMed]

et,

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Ezumi, A.

K. Fujii, M. Masutani, T. Okumura, D. Kawasaki, T. Akagami, A. Ezumi, T. Sakoda, T. Masuyama, and M. Ohyanagi, “Frequency and predictor of coronary thin-cap fibroatheroma in patients with acute myocardial infarction and stable angina pectoris a 3-vessel optical coherence tomography study,” J. Am. Coll. Cardiol.52(9), 787–788 (2008).
[CrossRef] [PubMed]

Falk, E.

E. Falk, “Plaque rupture with severe pre-existing stenosis precipitating coronary thrombosis. Characteristics of coronary atherosclerotic plaques underlying fatal occlusive thrombi,” Br. Heart J.50(2), 127–134 (1983).
[CrossRef] [PubMed]

Farb, A.

R. Virmani, A. P. Burke, F. D. Kolodgie, and A. Farb, “Vulnerable plaque: the pathology of unstable coronary lesions,” J. Interv. Cardiol.15(6), 439–446 (2002).
[CrossRef] [PubMed]

R. Virmani, F. D. Kolodgie, A. P. Burke, A. Farb, and S. M. Schwartz, “Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions,” Arterioscler. Thromb. Vasc. Biol.20(5), 1262–1275 (2000).
[CrossRef] [PubMed]

A. P. Burke, A. Farb, G. T. Malcom, Y. H. Liang, J. Smialek, and R. Virmani, “Coronary risk factors and plaque morphology in men with coronary disease who died suddenly,” N. Engl. J. Med.336(18), 1276–1282 (1997).
[CrossRef] [PubMed]

Finet, G.

J. Ohayon, G. Finet, A. M. Gharib, D. A. Herzka, P. Tracqui, J. Heroux, G. Rioufol, M. S. Kotys, A. Elagha, and R. I. Pettigrew, “Necrotic core thickness and positive arterial remodeling index: emergent biomechanical factors for evaluating the risk of plaque rupture,” Am. J. Physiol. Heart Circ. Physiol.295(2), H717–H727 (2008).
[CrossRef] [PubMed]

Flotte, T.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Ford, E. S.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Fox, C. S.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Fujii, K.

K. Fujii, M. Masutani, T. Okumura, D. Kawasaki, T. Akagami, A. Ezumi, T. Sakoda, T. Masuyama, and M. Ohyanagi, “Frequency and predictor of coronary thin-cap fibroatheroma in patients with acute myocardial infarction and stable angina pectoris a 3-vessel optical coherence tomography study,” J. Am. Coll. Cardiol.52(9), 787–788 (2008).
[CrossRef] [PubMed]

Fujiwara, H.

T. Yonetsu, T. Kakuta, T. Lee, K. Takahashi, N. Kawaguchi, G. Yamamoto, K. Koura, K. Hishikari, Y. Iesaka, H. Fujiwara, and M. Isobe, “In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography,” Eur. Heart J.32(10), 1251–1259 (2011).
[CrossRef] [PubMed]

Fullerton, H. J.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Ganatos, P.

Y. Vengrenyuk, S. Carlier, S. Xanthos, L. Cardoso, P. Ganatos, R. Virmani, S. Einav, L. Gilchrist, and S. Weinbaum, “A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps,” Proc. Natl. Acad. Sci. U.S.A.103(40), 14678–14683 (2006).
[CrossRef] [PubMed]

Gauthier, D. D.

O. C. Raffel, F. M. Merchant, G. J. Tearney, S. Chia, D. D. Gauthier, E. Pomerantsev, K. Mizuno, B. E. Bouma, and I.-K. Jang, “In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography,” Eur. Heart J.29(14), 1721–1728 (2008).
[CrossRef] [PubMed]

Gharib, A. M.

J. Ohayon, G. Finet, A. M. Gharib, D. A. Herzka, P. Tracqui, J. Heroux, G. Rioufol, M. S. Kotys, A. Elagha, and R. I. Pettigrew, “Necrotic core thickness and positive arterial remodeling index: emergent biomechanical factors for evaluating the risk of plaque rupture,” Am. J. Physiol. Heart Circ. Physiol.295(2), H717–H727 (2008).
[CrossRef] [PubMed]

Gilchrist, L.

Y. Vengrenyuk, S. Carlier, S. Xanthos, L. Cardoso, P. Ganatos, R. Virmani, S. Einav, L. Gilchrist, and S. Weinbaum, “A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps,” Proc. Natl. Acad. Sci. U.S.A.103(40), 14678–14683 (2006).
[CrossRef] [PubMed]

Gillespie, C.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Go, A. S.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Goderie, T.

G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
[CrossRef] [PubMed]

Gonzalo, N.

G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
[CrossRef] [PubMed]

Greenlund, K. J.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Gregory, K.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Guagliumi, G.

H. G. Bezerra, M. A. Costa, G. Guagliumi, A. M. Rollins, and D. I. Simon, “Intracoronary optical coherence tomography: a comprehensive review clinical and research applications,” JACC Cardiovasc. Interv.2(11), 1035–1046 (2009).
[CrossRef] [PubMed]

Hailpern, S. M.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Halpern, E. F.

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, “Characterization of human atherosclerosis by optical coherence tomography,” Circulation106(13), 1640–1645 (2002).
[CrossRef] [PubMed]

Hee, M. R.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Heit, J. A.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Heroux, J.

J. Ohayon, G. Finet, A. M. Gharib, D. A. Herzka, P. Tracqui, J. Heroux, G. Rioufol, M. S. Kotys, A. Elagha, and R. I. Pettigrew, “Necrotic core thickness and positive arterial remodeling index: emergent biomechanical factors for evaluating the risk of plaque rupture,” Am. J. Physiol. Heart Circ. Physiol.295(2), H717–H727 (2008).
[CrossRef] [PubMed]

Herzka, D. A.

J. Ohayon, G. Finet, A. M. Gharib, D. A. Herzka, P. Tracqui, J. Heroux, G. Rioufol, M. S. Kotys, A. Elagha, and R. I. Pettigrew, “Necrotic core thickness and positive arterial remodeling index: emergent biomechanical factors for evaluating the risk of plaque rupture,” Am. J. Physiol. Heart Circ. Physiol.295(2), H717–H727 (2008).
[CrossRef] [PubMed]

Hirata, K.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

Hishikari, K.

T. Yonetsu, T. Kakuta, T. Lee, K. Takahashi, N. Kawaguchi, G. Yamamoto, K. Koura, K. Hishikari, Y. Iesaka, H. Fujiwara, and M. Isobe, “In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography,” Eur. Heart J.32(10), 1251–1259 (2011).
[CrossRef] [PubMed]

Ho, P. M.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Hoffman, R. D.

M. S. Nguyen, O. Salvado, D. Roy, G. Steyer, M. E. Stone, R. D. Hoffman, and D. L. Wilson, “Ex vivo characterization of human atherosclerotic iliac plaque components using cryo-imaging,” J. Microsc.232(3), 432–441 (2008).
[CrossRef] [PubMed]

Houser, S. L.

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, “Characterization of human atherosclerosis by optical coherence tomography,” Circulation106(13), 1640–1645 (2002).
[CrossRef] [PubMed]

I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
[CrossRef] [PubMed]

Howard, V. J.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Huang, D.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Iesaka, Y.

T. Yonetsu, T. Kakuta, T. Lee, K. Takahashi, N. Kawaguchi, G. Yamamoto, K. Koura, K. Hishikari, Y. Iesaka, H. Fujiwara, and M. Isobe, “In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography,” Eur. Heart J.32(10), 1251–1259 (2011).
[CrossRef] [PubMed]

Ikejima, H.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

Imanishi, T.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

S. Takarada, T. Imanishi, T. Kubo, T. Tanimoto, H. Kitabata, N. Nakamura, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Effect of statin therapy on coronary fibrous-cap thickness in patients with acute coronary syndrome: assessment by optical coherence tomography study,” Atherosclerosis202(2), 491–497 (2009).
[CrossRef] [PubMed]

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
[CrossRef] [PubMed]

Ino, Y.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

Ishibashi, K.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

Isobe, M.

T. Yonetsu, T. Kakuta, T. Lee, K. Takahashi, N. Kawaguchi, G. Yamamoto, K. Koura, K. Hishikari, Y. Iesaka, H. Fujiwara, and M. Isobe, “In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography,” Eur. Heart J.32(10), 1251–1259 (2011).
[CrossRef] [PubMed]

Jang, I. K.

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, “Characterization of human atherosclerosis by optical coherence tomography,” Circulation106(13), 1640–1645 (2002).
[CrossRef] [PubMed]

Jang, I.-K.

O. C. Raffel, F. M. Merchant, G. J. Tearney, S. Chia, D. D. Gauthier, E. Pomerantsev, K. Mizuno, B. E. Bouma, and I.-K. Jang, “In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography,” Eur. Heart J.29(14), 1721–1728 (2008).
[CrossRef] [PubMed]

I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
[CrossRef] [PubMed]

Kakuta, T.

T. Yonetsu, T. Kakuta, T. Lee, K. Takahashi, N. Kawaguchi, G. Yamamoto, K. Koura, K. Hishikari, Y. Iesaka, H. Fujiwara, and M. Isobe, “In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography,” Eur. Heart J.32(10), 1251–1259 (2011).
[CrossRef] [PubMed]

Kang, D. H.

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, “Characterization of human atherosclerosis by optical coherence tomography,” Circulation106(13), 1640–1645 (2002).
[CrossRef] [PubMed]

Kang, D.-H.

I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
[CrossRef] [PubMed]

Kashiwaghi, M.

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

Kashiwagi, M.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

Kataiwa, H.

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

Katoh, O.

S. Rathore, M. Terashima, H. Matsuo, Y. Kinoshita, M. Kimura, E. Tsuchikane, K. Nasu, M. Ehara, Y. Asakura, O. Katoh, and T. Suzuki, “In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study,” Coron. Artery Dis.22(1), 64–72 (2011).
[CrossRef] [PubMed]

Kauffman, C. R.

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, “Characterization of human atherosclerosis by optical coherence tomography,” Circulation106(13), 1640–1645 (2002).
[CrossRef] [PubMed]

Kawaguchi, N.

T. Yonetsu, T. Kakuta, T. Lee, K. Takahashi, N. Kawaguchi, G. Yamamoto, K. Koura, K. Hishikari, Y. Iesaka, H. Fujiwara, and M. Isobe, “In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography,” Eur. Heart J.32(10), 1251–1259 (2011).
[CrossRef] [PubMed]

Kawamoto, T.

T. Kume, T. Akasaka, T. Kawamoto, H. Okura, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, and K. Yoshida, “Measurement of the thickness of the fibrous cap by optical coherence tomography,” Am. Heart J.152(4), 755.e1–e755.e4 (2006).
[CrossRef] [PubMed]

Kawasaki, D.

K. Fujii, M. Masutani, T. Okumura, D. Kawasaki, T. Akagami, A. Ezumi, T. Sakoda, T. Masuyama, and M. Ohyanagi, “Frequency and predictor of coronary thin-cap fibroatheroma in patients with acute myocardial infarction and stable angina pectoris a 3-vessel optical coherence tomography study,” J. Am. Coll. Cardiol.52(9), 787–788 (2008).
[CrossRef] [PubMed]

Kimura, K.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

Kimura, M.

S. Rathore, M. Terashima, H. Matsuo, Y. Kinoshita, M. Kimura, E. Tsuchikane, K. Nasu, M. Ehara, Y. Asakura, O. Katoh, and T. Suzuki, “In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study,” Coron. Artery Dis.22(1), 64–72 (2011).
[CrossRef] [PubMed]

Kinoshita, Y.

S. Rathore, M. Terashima, H. Matsuo, Y. Kinoshita, M. Kimura, E. Tsuchikane, K. Nasu, M. Ehara, Y. Asakura, O. Katoh, and T. Suzuki, “In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study,” Coron. Artery Dis.22(1), 64–72 (2011).
[CrossRef] [PubMed]

Kissela, B. M.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Kitabata, H.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

S. Takarada, T. Imanishi, T. Kubo, T. Tanimoto, H. Kitabata, N. Nakamura, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Effect of statin therapy on coronary fibrous-cap thickness in patients with acute coronary syndrome: assessment by optical coherence tomography study,” Atherosclerosis202(2), 491–497 (2009).
[CrossRef] [PubMed]

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
[CrossRef] [PubMed]

Kittner, S. J.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Koljenovic, S.

G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
[CrossRef] [PubMed]

Kolodgie, F. D.

R. Virmani, A. P. Burke, F. D. Kolodgie, and A. Farb, “Vulnerable plaque: the pathology of unstable coronary lesions,” J. Interv. Cardiol.15(6), 439–446 (2002).
[CrossRef] [PubMed]

R. Virmani, F. D. Kolodgie, A. P. Burke, A. Farb, and S. M. Schwartz, “Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions,” Arterioscler. Thromb. Vasc. Biol.20(5), 1262–1275 (2000).
[CrossRef] [PubMed]

Komukai, K.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

Kotys, M. S.

J. Ohayon, G. Finet, A. M. Gharib, D. A. Herzka, P. Tracqui, J. Heroux, G. Rioufol, M. S. Kotys, A. Elagha, and R. I. Pettigrew, “Necrotic core thickness and positive arterial remodeling index: emergent biomechanical factors for evaluating the risk of plaque rupture,” Am. J. Physiol. Heart Circ. Physiol.295(2), H717–H727 (2008).
[CrossRef] [PubMed]

Koura, K.

T. Yonetsu, T. Kakuta, T. Lee, K. Takahashi, N. Kawaguchi, G. Yamamoto, K. Koura, K. Hishikari, Y. Iesaka, H. Fujiwara, and M. Isobe, “In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography,” Eur. Heart J.32(10), 1251–1259 (2011).
[CrossRef] [PubMed]

Kubo, T.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

S. Takarada, T. Imanishi, T. Kubo, T. Tanimoto, H. Kitabata, N. Nakamura, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Effect of statin therapy on coronary fibrous-cap thickness in patients with acute coronary syndrome: assessment by optical coherence tomography study,” Atherosclerosis202(2), 491–497 (2009).
[CrossRef] [PubMed]

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
[CrossRef] [PubMed]

Kume, T.

T. Kume, T. Akasaka, T. Kawamoto, H. Okura, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, and K. Yoshida, “Measurement of the thickness of the fibrous cap by optical coherence tomography,” Am. Heart J.152(4), 755.e1–e755.e4 (2006).
[CrossRef] [PubMed]

Kuroi, A.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
[CrossRef] [PubMed]

Kyono, H.

Z. Wang, H. Kyono, H. Bezerra, D. Wilson, M. Costa, and A. Rollins, “Automatic segmentation of intravascular optical coherence tomography images for facilitating quantitative diagnosis of atherosclerosis,” Proc. SPIE7889, 78890N (2011).
[CrossRef]

Lackland, D. T.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Lee, T.

T. Yonetsu, T. Kakuta, T. Lee, K. Takahashi, N. Kawaguchi, G. Yamamoto, K. Koura, K. Hishikari, Y. Iesaka, H. Fujiwara, and M. Isobe, “In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography,” Eur. Heart J.32(10), 1251–1259 (2011).
[CrossRef] [PubMed]

Lendon, C. L.

C. L. Lendon, M. J. Davies, G. V. R. Born, and P. D. Richardson, “Atherosclerotic plaque caps are locally weakened when macrophages density is increased,” Atherosclerosis87(1), 87–90 (1991).
[CrossRef] [PubMed]

Liang, Y. H.

A. P. Burke, A. Farb, G. T. Malcom, Y. H. Liang, J. Smialek, and R. Virmani, “Coronary risk factors and plaque morphology in men with coronary disease who died suddenly,” N. Engl. J. Med.336(18), 1276–1282 (1997).
[CrossRef] [PubMed]

Lichtman, J. H.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Lin, C. P.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Lisabeth, L. D.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Lloyd-Jones, D. M.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Makuc, D. M.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Malcom, G. T.

A. P. Burke, A. Farb, G. T. Malcom, Y. H. Liang, J. Smialek, and R. Virmani, “Coronary risk factors and plaque morphology in men with coronary disease who died suddenly,” N. Engl. J. Med.336(18), 1276–1282 (1997).
[CrossRef] [PubMed]

Marcus, G. M.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Marelli, A.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Masho, T.

T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
[CrossRef] [PubMed]

Masutani, M.

K. Fujii, M. Masutani, T. Okumura, D. Kawasaki, T. Akagami, A. Ezumi, T. Sakoda, T. Masuyama, and M. Ohyanagi, “Frequency and predictor of coronary thin-cap fibroatheroma in patients with acute myocardial infarction and stable angina pectoris a 3-vessel optical coherence tomography study,” J. Am. Coll. Cardiol.52(9), 787–788 (2008).
[CrossRef] [PubMed]

Masuyama, T.

K. Fujii, M. Masutani, T. Okumura, D. Kawasaki, T. Akagami, A. Ezumi, T. Sakoda, T. Masuyama, and M. Ohyanagi, “Frequency and predictor of coronary thin-cap fibroatheroma in patients with acute myocardial infarction and stable angina pectoris a 3-vessel optical coherence tomography study,” J. Am. Coll. Cardiol.52(9), 787–788 (2008).
[CrossRef] [PubMed]

Matchar, D. B.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Matsumoto, H.

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

Matsuo, H.

S. Rathore, M. Terashima, H. Matsuo, Y. Kinoshita, M. Kimura, E. Tsuchikane, K. Nasu, M. Ehara, Y. Asakura, O. Katoh, and T. Suzuki, “In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study,” Coron. Artery Dis.22(1), 64–72 (2011).
[CrossRef] [PubMed]

Matsuo, Y.

T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
[CrossRef] [PubMed]

McDermott, M. M.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Meigs, J. B.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Merchant, F. M.

O. C. Raffel, F. M. Merchant, G. J. Tearney, S. Chia, D. D. Gauthier, E. Pomerantsev, K. Mizuno, B. E. Bouma, and I.-K. Jang, “In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography,” Eur. Heart J.29(14), 1721–1728 (2008).
[CrossRef] [PubMed]

Mizukoshi, M.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

S. Takarada, T. Imanishi, T. Kubo, T. Tanimoto, H. Kitabata, N. Nakamura, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Effect of statin therapy on coronary fibrous-cap thickness in patients with acute coronary syndrome: assessment by optical coherence tomography study,” Atherosclerosis202(2), 491–497 (2009).
[CrossRef] [PubMed]

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

Mizuno, K.

O. C. Raffel, F. M. Merchant, G. J. Tearney, S. Chia, D. D. Gauthier, E. Pomerantsev, K. Mizuno, B. E. Bouma, and I.-K. Jang, “In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography,” Eur. Heart J.29(14), 1721–1728 (2008).
[CrossRef] [PubMed]

Moy, C. S.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Mozaffarian, D.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Mussolino, M. E.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Nakamura, N.

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

S. Takarada, T. Imanishi, T. Kubo, T. Tanimoto, H. Kitabata, N. Nakamura, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Effect of statin therapy on coronary fibrous-cap thickness in patients with acute coronary syndrome: assessment by optical coherence tomography study,” Atherosclerosis202(2), 491–497 (2009).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

Nasu, K.

S. Rathore, M. Terashima, H. Matsuo, Y. Kinoshita, M. Kimura, E. Tsuchikane, K. Nasu, M. Ehara, Y. Asakura, O. Katoh, and T. Suzuki, “In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study,” Coron. Artery Dis.22(1), 64–72 (2011).
[CrossRef] [PubMed]

Neishi, Y.

T. Kume, T. Akasaka, T. Kawamoto, H. Okura, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, and K. Yoshida, “Measurement of the thickness of the fibrous cap by optical coherence tomography,” Am. Heart J.152(4), 755.e1–e755.e4 (2006).
[CrossRef] [PubMed]

Nguyen, M. S.

M. S. Nguyen, O. Salvado, D. Roy, G. Steyer, M. E. Stone, R. D. Hoffman, and D. L. Wilson, “Ex vivo characterization of human atherosclerotic iliac plaque components using cryo-imaging,” J. Microsc.232(3), 432–441 (2008).
[CrossRef] [PubMed]

Nichol, G.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Ohayon, J.

J. Ohayon, G. Finet, A. M. Gharib, D. A. Herzka, P. Tracqui, J. Heroux, G. Rioufol, M. S. Kotys, A. Elagha, and R. I. Pettigrew, “Necrotic core thickness and positive arterial remodeling index: emergent biomechanical factors for evaluating the risk of plaque rupture,” Am. J. Physiol. Heart Circ. Physiol.295(2), H717–H727 (2008).
[CrossRef] [PubMed]

Ohyanagi, M.

K. Fujii, M. Masutani, T. Okumura, D. Kawasaki, T. Akagami, A. Ezumi, T. Sakoda, T. Masuyama, and M. Ohyanagi, “Frequency and predictor of coronary thin-cap fibroatheroma in patients with acute myocardial infarction and stable angina pectoris a 3-vessel optical coherence tomography study,” J. Am. Coll. Cardiol.52(9), 787–788 (2008).
[CrossRef] [PubMed]

Okamura, T.

G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
[CrossRef] [PubMed]

Okouchi, K.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

Okumura, T.

K. Fujii, M. Masutani, T. Okumura, D. Kawasaki, T. Akagami, A. Ezumi, T. Sakoda, T. Masuyama, and M. Ohyanagi, “Frequency and predictor of coronary thin-cap fibroatheroma in patients with acute myocardial infarction and stable angina pectoris a 3-vessel optical coherence tomography study,” J. Am. Coll. Cardiol.52(9), 787–788 (2008).
[CrossRef] [PubMed]

Okura, H.

T. Kume, T. Akasaka, T. Kawamoto, H. Okura, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, and K. Yoshida, “Measurement of the thickness of the fibrous cap by optical coherence tomography,” Am. Heart J.152(4), 755.e1–e755.e4 (2006).
[CrossRef] [PubMed]

Ookochi, K.

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

Oosterhuis, J. W.

G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
[CrossRef] [PubMed]

Park, S.-J.

I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
[CrossRef] [PubMed]

Park, S.-W.

I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
[CrossRef] [PubMed]

Paynter, N. P.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Pettigrew, R. I.

J. Ohayon, G. Finet, A. M. Gharib, D. A. Herzka, P. Tracqui, J. Heroux, G. Rioufol, M. S. Kotys, A. Elagha, and R. I. Pettigrew, “Necrotic core thickness and positive arterial remodeling index: emergent biomechanical factors for evaluating the risk of plaque rupture,” Am. J. Physiol. Heart Circ. Physiol.295(2), H717–H727 (2008).
[CrossRef] [PubMed]

Pomerantsev, E.

O. C. Raffel, F. M. Merchant, G. J. Tearney, S. Chia, D. D. Gauthier, E. Pomerantsev, K. Mizuno, B. E. Bouma, and I.-K. Jang, “In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography,” Eur. Heart J.29(14), 1721–1728 (2008).
[CrossRef] [PubMed]

I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
[CrossRef] [PubMed]

Puliafito, C. A.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Raffel, O. C.

O. C. Raffel, F. M. Merchant, G. J. Tearney, S. Chia, D. D. Gauthier, E. Pomerantsev, K. Mizuno, B. E. Bouma, and I.-K. Jang, “In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography,” Eur. Heart J.29(14), 1721–1728 (2008).
[CrossRef] [PubMed]

Rathore, S.

S. Rathore, M. Terashima, H. Matsuo, Y. Kinoshita, M. Kimura, E. Tsuchikane, K. Nasu, M. Ehara, Y. Asakura, O. Katoh, and T. Suzuki, “In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study,” Coron. Artery Dis.22(1), 64–72 (2011).
[CrossRef] [PubMed]

Regar, E.

G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
[CrossRef] [PubMed]

Richardson, P. D.

C. L. Lendon, M. J. Davies, G. V. R. Born, and P. D. Richardson, “Atherosclerotic plaque caps are locally weakened when macrophages density is increased,” Atherosclerosis87(1), 87–90 (1991).
[CrossRef] [PubMed]

Rioufol, G.

J. Ohayon, G. Finet, A. M. Gharib, D. A. Herzka, P. Tracqui, J. Heroux, G. Rioufol, M. S. Kotys, A. Elagha, and R. I. Pettigrew, “Necrotic core thickness and positive arterial remodeling index: emergent biomechanical factors for evaluating the risk of plaque rupture,” Am. J. Physiol. Heart Circ. Physiol.295(2), H717–H727 (2008).
[CrossRef] [PubMed]

Roger, V. L.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Rollins, A.

Z. Wang, H. Kyono, H. Bezerra, D. Wilson, M. Costa, and A. Rollins, “Automatic segmentation of intravascular optical coherence tomography images for facilitating quantitative diagnosis of atherosclerosis,” Proc. SPIE7889, 78890N (2011).
[CrossRef]

Rollins, A. M.

H. G. Bezerra, M. A. Costa, G. Guagliumi, A. M. Rollins, and D. I. Simon, “Intracoronary optical coherence tomography: a comprehensive review clinical and research applications,” JACC Cardiovasc. Interv.2(11), 1035–1046 (2009).
[CrossRef] [PubMed]

Rosamond, W. D.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Roy, D.

M. S. Nguyen, O. Salvado, D. Roy, G. Steyer, M. E. Stone, R. D. Hoffman, and D. L. Wilson, “Ex vivo characterization of human atherosclerotic iliac plaque components using cryo-imaging,” J. Microsc.232(3), 432–441 (2008).
[CrossRef] [PubMed]

Sadahira, Y.

T. Kume, T. Akasaka, T. Kawamoto, H. Okura, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, and K. Yoshida, “Measurement of the thickness of the fibrous cap by optical coherence tomography,” Am. Heart J.152(4), 755.e1–e755.e4 (2006).
[CrossRef] [PubMed]

Sakoda, T.

K. Fujii, M. Masutani, T. Okumura, D. Kawasaki, T. Akagami, A. Ezumi, T. Sakoda, T. Masuyama, and M. Ohyanagi, “Frequency and predictor of coronary thin-cap fibroatheroma in patients with acute myocardial infarction and stable angina pectoris a 3-vessel optical coherence tomography study,” J. Am. Coll. Cardiol.52(9), 787–788 (2008).
[CrossRef] [PubMed]

Salvado, O.

M. S. Nguyen, O. Salvado, D. Roy, G. Steyer, M. E. Stone, R. D. Hoffman, and D. L. Wilson, “Ex vivo characterization of human atherosclerotic iliac plaque components using cryo-imaging,” J. Microsc.232(3), 432–441 (2008).
[CrossRef] [PubMed]

Schlendorf, K.

I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
[CrossRef] [PubMed]

Schlendorf, K. H.

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, “Characterization of human atherosclerosis by optical coherence tomography,” Circulation106(13), 1640–1645 (2002).
[CrossRef] [PubMed]

Schmitt, J. M.

C. Xu, J. M. Schmitt, S. G. Carlier, and R. Virmani, “Characterization of atherosclerosis plaques by measuring both backscattering and attenuation coefficients in optical coherence tomography,” J. Biomed. Opt.13(3), 034003–034008 (2008).
[CrossRef] [PubMed]

Schuman, J. S.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Schwartz, S. M.

R. Virmani, F. D. Kolodgie, A. P. Burke, A. Farb, and S. M. Schwartz, “Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions,” Arterioscler. Thromb. Vasc. Biol.20(5), 1262–1275 (2000).
[CrossRef] [PubMed]

Serruys, P. W.

G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
[CrossRef] [PubMed]

Seung, K.-B.

I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
[CrossRef] [PubMed]

Shishkov, M.

I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
[CrossRef] [PubMed]

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, “Characterization of human atherosclerosis by optical coherence tomography,” Circulation106(13), 1640–1645 (2002).
[CrossRef] [PubMed]

Simon, D. I.

H. G. Bezerra, M. A. Costa, G. Guagliumi, A. M. Rollins, and D. I. Simon, “Intracoronary optical coherence tomography: a comprehensive review clinical and research applications,” JACC Cardiovasc. Interv.2(11), 1035–1046 (2009).
[CrossRef] [PubMed]

Smialek, J.

A. P. Burke, A. Farb, G. T. Malcom, Y. H. Liang, J. Smialek, and R. Virmani, “Coronary risk factors and plaque morphology in men with coronary disease who died suddenly,” N. Engl. J. Med.336(18), 1276–1282 (1997).
[CrossRef] [PubMed]

Sorlie, P. D.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Stafford, R. S.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Steyer, G.

M. S. Nguyen, O. Salvado, D. Roy, G. Steyer, M. E. Stone, R. D. Hoffman, and D. L. Wilson, “Ex vivo characterization of human atherosclerotic iliac plaque components using cryo-imaging,” J. Microsc.232(3), 432–441 (2008).
[CrossRef] [PubMed]

Stinson, W. G.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Stone, M. E.

M. S. Nguyen, O. Salvado, D. Roy, G. Steyer, M. E. Stone, R. D. Hoffman, and D. L. Wilson, “Ex vivo characterization of human atherosclerotic iliac plaque components using cryo-imaging,” J. Microsc.232(3), 432–441 (2008).
[CrossRef] [PubMed]

Sukmawan, R.

T. Kume, T. Akasaka, T. Kawamoto, H. Okura, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, and K. Yoshida, “Measurement of the thickness of the fibrous cap by optical coherence tomography,” Am. Heart J.152(4), 755.e1–e755.e4 (2006).
[CrossRef] [PubMed]

Suzuki, T.

S. Rathore, M. Terashima, H. Matsuo, Y. Kinoshita, M. Kimura, E. Tsuchikane, K. Nasu, M. Ehara, Y. Asakura, O. Katoh, and T. Suzuki, “In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study,” Coron. Artery Dis.22(1), 64–72 (2011).
[CrossRef] [PubMed]

Swanson, E. A.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Takahashi, K.

T. Yonetsu, T. Kakuta, T. Lee, K. Takahashi, N. Kawaguchi, G. Yamamoto, K. Koura, K. Hishikari, Y. Iesaka, H. Fujiwara, and M. Isobe, “In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography,” Eur. Heart J.32(10), 1251–1259 (2011).
[CrossRef] [PubMed]

Takarada, S.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

S. Takarada, T. Imanishi, T. Kubo, T. Tanimoto, H. Kitabata, N. Nakamura, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Effect of statin therapy on coronary fibrous-cap thickness in patients with acute coronary syndrome: assessment by optical coherence tomography study,” Atherosclerosis202(2), 491–497 (2009).
[CrossRef] [PubMed]

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
[CrossRef] [PubMed]

Takemoto, K.

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

Tanaka, A.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

S. Takarada, T. Imanishi, T. Kubo, T. Tanimoto, H. Kitabata, N. Nakamura, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Effect of statin therapy on coronary fibrous-cap thickness in patients with acute coronary syndrome: assessment by optical coherence tomography study,” Atherosclerosis202(2), 491–497 (2009).
[CrossRef] [PubMed]

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

Tanimoto, T.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

S. Takarada, T. Imanishi, T. Kubo, T. Tanimoto, H. Kitabata, N. Nakamura, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Effect of statin therapy on coronary fibrous-cap thickness in patients with acute coronary syndrome: assessment by optical coherence tomography study,” Atherosclerosis202(2), 491–497 (2009).
[CrossRef] [PubMed]

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
[CrossRef] [PubMed]

Tearney, G. J.

G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
[CrossRef] [PubMed]

O. C. Raffel, F. M. Merchant, G. J. Tearney, S. Chia, D. D. Gauthier, E. Pomerantsev, K. Mizuno, B. E. Bouma, and I.-K. Jang, “In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography,” Eur. Heart J.29(14), 1721–1728 (2008).
[CrossRef] [PubMed]

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, “Characterization of human atherosclerosis by optical coherence tomography,” Circulation106(13), 1640–1645 (2002).
[CrossRef] [PubMed]

I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
[CrossRef] [PubMed]

Terashima, M.

S. Rathore, M. Terashima, H. Matsuo, Y. Kinoshita, M. Kimura, E. Tsuchikane, K. Nasu, M. Ehara, Y. Asakura, O. Katoh, and T. Suzuki, “In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study,” Coron. Artery Dis.22(1), 64–72 (2011).
[CrossRef] [PubMed]

Tomobuchi, Y.

T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
[CrossRef] [PubMed]

Toyota, E.

T. Kume, T. Akasaka, T. Kawamoto, H. Okura, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, and K. Yoshida, “Measurement of the thickness of the fibrous cap by optical coherence tomography,” Am. Heart J.152(4), 755.e1–e755.e4 (2006).
[CrossRef] [PubMed]

Tracqui, P.

J. Ohayon, G. Finet, A. M. Gharib, D. A. Herzka, P. Tracqui, J. Heroux, G. Rioufol, M. S. Kotys, A. Elagha, and R. I. Pettigrew, “Necrotic core thickness and positive arterial remodeling index: emergent biomechanical factors for evaluating the risk of plaque rupture,” Am. J. Physiol. Heart Circ. Physiol.295(2), H717–H727 (2008).
[CrossRef] [PubMed]

Tsuchikane, E.

S. Rathore, M. Terashima, H. Matsuo, Y. Kinoshita, M. Kimura, E. Tsuchikane, K. Nasu, M. Ehara, Y. Asakura, O. Katoh, and T. Suzuki, “In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study,” Coron. Artery Dis.22(1), 64–72 (2011).
[CrossRef] [PubMed]

Tsuda, K.

T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
[CrossRef] [PubMed]

Tsujioka, H.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

Turan, T. N.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Turner, M. B.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Ueno, S.

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
[CrossRef] [PubMed]

van der Steen, A. F.

G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
[CrossRef] [PubMed]

van der Steen, A. F. W.

G. van Soest, J. G. Bosch, and A. F. W. van der Steen, “Azimuthal registration of image sequences affected by nonuniform rotation distortion,” IEEE Trans. Inf. Technol. Biomed.12(3), 348–355 (2008).
[CrossRef] [PubMed]

van Leenders, G. L.

G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
[CrossRef] [PubMed]

van Noorden, S.

G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
[CrossRef] [PubMed]

van Soest, G.

G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
[CrossRef] [PubMed]

G. van Soest, J. G. Bosch, and A. F. W. van der Steen, “Azimuthal registration of image sequences affected by nonuniform rotation distortion,” IEEE Trans. Inf. Technol. Biomed.12(3), 348–355 (2008).
[CrossRef] [PubMed]

Vengrenyuk, Y.

Y. Vengrenyuk, S. Carlier, S. Xanthos, L. Cardoso, P. Ganatos, R. Virmani, S. Einav, L. Gilchrist, and S. Weinbaum, “A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps,” Proc. Natl. Acad. Sci. U.S.A.103(40), 14678–14683 (2006).
[CrossRef] [PubMed]

Virmani, R.

C. Xu, J. M. Schmitt, S. G. Carlier, and R. Virmani, “Characterization of atherosclerosis plaques by measuring both backscattering and attenuation coefficients in optical coherence tomography,” J. Biomed. Opt.13(3), 034003–034008 (2008).
[CrossRef] [PubMed]

Y. Vengrenyuk, S. Carlier, S. Xanthos, L. Cardoso, P. Ganatos, R. Virmani, S. Einav, L. Gilchrist, and S. Weinbaum, “A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps,” Proc. Natl. Acad. Sci. U.S.A.103(40), 14678–14683 (2006).
[CrossRef] [PubMed]

R. Virmani, A. P. Burke, F. D. Kolodgie, and A. Farb, “Vulnerable plaque: the pathology of unstable coronary lesions,” J. Interv. Cardiol.15(6), 439–446 (2002).
[CrossRef] [PubMed]

R. Virmani, F. D. Kolodgie, A. P. Burke, A. Farb, and S. M. Schwartz, “Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions,” Arterioscler. Thromb. Vasc. Biol.20(5), 1262–1275 (2000).
[CrossRef] [PubMed]

A. P. Burke, A. Farb, G. T. Malcom, Y. H. Liang, J. Smialek, and R. Virmani, “Coronary risk factors and plaque morphology in men with coronary disease who died suddenly,” N. Engl. J. Med.336(18), 1276–1282 (1997).
[CrossRef] [PubMed]

Wang, Z.

Z. Wang, H. Kyono, H. Bezerra, D. Wilson, M. Costa, and A. Rollins, “Automatic segmentation of intravascular optical coherence tomography images for facilitating quantitative diagnosis of atherosclerosis,” Proc. SPIE7889, 78890N (2011).
[CrossRef]

Watanabe, N.

T. Kume, T. Akasaka, T. Kawamoto, H. Okura, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, and K. Yoshida, “Measurement of the thickness of the fibrous cap by optical coherence tomography,” Am. Heart J.152(4), 755.e1–e755.e4 (2006).
[CrossRef] [PubMed]

Weinbaum, S.

Y. Vengrenyuk, S. Carlier, S. Xanthos, L. Cardoso, P. Ganatos, R. Virmani, S. Einav, L. Gilchrist, and S. Weinbaum, “A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps,” Proc. Natl. Acad. Sci. U.S.A.103(40), 14678–14683 (2006).
[CrossRef] [PubMed]

Wilson, D.

Z. Wang, H. Kyono, H. Bezerra, D. Wilson, M. Costa, and A. Rollins, “Automatic segmentation of intravascular optical coherence tomography images for facilitating quantitative diagnosis of atherosclerosis,” Proc. SPIE7889, 78890N (2011).
[CrossRef]

Wilson, D. L.

M. S. Nguyen, O. Salvado, D. Roy, G. Steyer, M. E. Stone, R. D. Hoffman, and D. L. Wilson, “Ex vivo characterization of human atherosclerotic iliac plaque components using cryo-imaging,” J. Microsc.232(3), 432–441 (2008).
[CrossRef] [PubMed]

Wong, N. D.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Wylie-Rosett, J.

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

Xanthos, S.

Y. Vengrenyuk, S. Carlier, S. Xanthos, L. Cardoso, P. Ganatos, R. Virmani, S. Einav, L. Gilchrist, and S. Weinbaum, “A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps,” Proc. Natl. Acad. Sci. U.S.A.103(40), 14678–14683 (2006).
[CrossRef] [PubMed]

Xu, C.

C. Xu, J. M. Schmitt, S. G. Carlier, and R. Virmani, “Characterization of atherosclerosis plaques by measuring both backscattering and attenuation coefficients in optical coherence tomography,” J. Biomed. Opt.13(3), 034003–034008 (2008).
[CrossRef] [PubMed]

Yabushita, H.

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, “Characterization of human atherosclerosis by optical coherence tomography,” Circulation106(13), 1640–1645 (2002).
[CrossRef] [PubMed]

Yamamoto, G.

T. Yonetsu, T. Kakuta, T. Lee, K. Takahashi, N. Kawaguchi, G. Yamamoto, K. Koura, K. Hishikari, Y. Iesaka, H. Fujiwara, and M. Isobe, “In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography,” Eur. Heart J.32(10), 1251–1259 (2011).
[CrossRef] [PubMed]

Yamano, T.

T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
[CrossRef] [PubMed]

Yonetsu, T.

T. Yonetsu, T. Kakuta, T. Lee, K. Takahashi, N. Kawaguchi, G. Yamamoto, K. Koura, K. Hishikari, Y. Iesaka, H. Fujiwara, and M. Isobe, “In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography,” Eur. Heart J.32(10), 1251–1259 (2011).
[CrossRef] [PubMed]

Yoshida, K.

T. Kume, T. Akasaka, T. Kawamoto, H. Okura, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, and K. Yoshida, “Measurement of the thickness of the fibrous cap by optical coherence tomography,” Am. Heart J.152(4), 755.e1–e755.e4 (2006).
[CrossRef] [PubMed]

Am. Heart J.

T. Kume, T. Akasaka, T. Kawamoto, H. Okura, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, and K. Yoshida, “Measurement of the thickness of the fibrous cap by optical coherence tomography,” Am. Heart J.152(4), 755.e1–e755.e4 (2006).
[CrossRef] [PubMed]

Am. J. Cardiol.

T. Kubo, T. Imanishi, M. Kashiwagi, H. Ikejima, H. Tsujioka, A. Kuroi, K. Ishibashi, K. Komukai, T. Tanimoto, Y. Ino, H. Kitabata, S. Takarada, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Multiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomography,” Am. J. Cardiol.105(3), 318–322 (2010).
[CrossRef] [PubMed]

Am. J. Physiol. Heart Circ. Physiol.

J. Ohayon, G. Finet, A. M. Gharib, D. A. Herzka, P. Tracqui, J. Heroux, G. Rioufol, M. S. Kotys, A. Elagha, and R. I. Pettigrew, “Necrotic core thickness and positive arterial remodeling index: emergent biomechanical factors for evaluating the risk of plaque rupture,” Am. J. Physiol. Heart Circ. Physiol.295(2), H717–H727 (2008).
[CrossRef] [PubMed]

Arterioscler. Thromb. Vasc. Biol.

R. Virmani, F. D. Kolodgie, A. P. Burke, A. Farb, and S. M. Schwartz, “Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions,” Arterioscler. Thromb. Vasc. Biol.20(5), 1262–1275 (2000).
[CrossRef] [PubMed]

Atherosclerosis

S. Takarada, T. Imanishi, T. Kubo, T. Tanimoto, H. Kitabata, N. Nakamura, A. Tanaka, M. Mizukoshi, and T. Akasaka, “Effect of statin therapy on coronary fibrous-cap thickness in patients with acute coronary syndrome: assessment by optical coherence tomography study,” Atherosclerosis202(2), 491–497 (2009).
[CrossRef] [PubMed]

C. L. Lendon, M. J. Davies, G. V. R. Born, and P. D. Richardson, “Atherosclerotic plaque caps are locally weakened when macrophages density is increased,” Atherosclerosis87(1), 87–90 (1991).
[CrossRef] [PubMed]

Br. Heart J.

E. Falk, “Plaque rupture with severe pre-existing stenosis precipitating coronary thrombosis. Characteristics of coronary atherosclerotic plaques underlying fatal occlusive thrombi,” Br. Heart J.50(2), 127–134 (1983).
[CrossRef] [PubMed]

Circ. J.

M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Matsumoto, Y. Arita, K. Ookochi, A. Kuroi, H. Kataiwa, T. Tanimoto, H. Ikejima, S. Takarada, T. Kubo, K. Hirata, N. Nakamura, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Relationship between coronary arterial remodeling, fibrous cap thickness and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome,” Circ. J.73(7), 1291–1295 (2009).
[CrossRef] [PubMed]

Circulation

V. L. Roger, A. S. Go, D. M. Lloyd-Jones, R. J. Adams, J. D. Berry, T. M. Brown, M. R. Carnethon, S. Dai, G. de Simone, E. S. Ford, C. S. Fox, H. J. Fullerton, C. Gillespie, K. J. Greenlund, S. M. Hailpern, J. A. Heit, P. M. Ho, V. J. Howard, B. M. Kissela, S. J. Kittner, D. T. Lackland, J. H. Lichtman, L. D. Lisabeth, D. M. Makuc, G. M. Marcus, A. Marelli, D. B. Matchar, M. M. McDermott, J. B. Meigs, C. S. Moy, D. Mozaffarian, M. E. Mussolino, G. Nichol, N. P. Paynter, W. D. Rosamond, P. D. Sorlie, R. S. Stafford, T. N. Turan, M. B. Turner, N. D. Wong, J. Wylie-Rosett, V. L. Roger, M. B. Turner, and American Heart Association Statistics Committee and Stroke Statistics Subcommittee, “Heart disease and stroke statistics—2011 update: a report from the American Heart Association,” Circulation123(4), e18–e209 (2011).
[CrossRef] [PubMed]

A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, and T. Akasaka, “Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study,” Circulation118(23), 2368–2373 (2008).
[CrossRef] [PubMed]

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, “Characterization of human atherosclerosis by optical coherence tomography,” Circulation106(13), 1640–1645 (2002).
[CrossRef] [PubMed]

Coron. Artery Dis.

S. Rathore, M. Terashima, H. Matsuo, Y. Kinoshita, M. Kimura, E. Tsuchikane, K. Nasu, M. Ehara, Y. Asakura, O. Katoh, and T. Suzuki, “In-vivo detection of the frequency and distribution of thin-cap fibroatheroma and ruptured plaques in patients with coronary artery disease: an optical coherence tomographic study,” Coron. Artery Dis.22(1), 64–72 (2011).
[CrossRef] [PubMed]

Eur. Heart J.

T. Yonetsu, T. Kakuta, T. Lee, K. Takahashi, N. Kawaguchi, G. Yamamoto, K. Koura, K. Hishikari, Y. Iesaka, H. Fujiwara, and M. Isobe, “In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography,” Eur. Heart J.32(10), 1251–1259 (2011).
[CrossRef] [PubMed]

O. C. Raffel, F. M. Merchant, G. J. Tearney, S. Chia, D. D. Gauthier, E. Pomerantsev, K. Mizuno, B. E. Bouma, and I.-K. Jang, “In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography,” Eur. Heart J.29(14), 1721–1728 (2008).
[CrossRef] [PubMed]

IEEE Trans. Inf. Technol. Biomed.

G. van Soest, J. G. Bosch, and A. F. W. van der Steen, “Azimuthal registration of image sequences affected by nonuniform rotation distortion,” IEEE Trans. Inf. Technol. Biomed.12(3), 348–355 (2008).
[CrossRef] [PubMed]

J. Am. Coll. Cardiol.

I.-K. Jang, B. E. Bouma, D.-H. Kang, S.-J. Park, S.-W. Park, K.-B. Seung, K.-B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol.39(4), 604–609 (2002).
[CrossRef] [PubMed]

T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, H. Kitabata, K. Tsuda, Y. Tomobuchi, and T. Akasaka, “Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy,” J. Am. Coll. Cardiol.50(10), 933–939 (2007).
[CrossRef] [PubMed]

K. Fujii, M. Masutani, T. Okumura, D. Kawasaki, T. Akagami, A. Ezumi, T. Sakoda, T. Masuyama, and M. Ohyanagi, “Frequency and predictor of coronary thin-cap fibroatheroma in patients with acute myocardial infarction and stable angina pectoris a 3-vessel optical coherence tomography study,” J. Am. Coll. Cardiol.52(9), 787–788 (2008).
[CrossRef] [PubMed]

J. Biomed. Opt.

G. van Soest, T. Goderie, E. Regar, S. Koljenović, G. L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B. E. Bouma, G. J. Tearney, J. W. Oosterhuis, P. W. Serruys, and A. F. van der Steen, “Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging,” J. Biomed. Opt.15(1), 011105 (2010).
[CrossRef] [PubMed]

C. Xu, J. M. Schmitt, S. G. Carlier, and R. Virmani, “Characterization of atherosclerosis plaques by measuring both backscattering and attenuation coefficients in optical coherence tomography,” J. Biomed. Opt.13(3), 034003–034008 (2008).
[CrossRef] [PubMed]

J. Interv. Cardiol.

R. Virmani, A. P. Burke, F. D. Kolodgie, and A. Farb, “Vulnerable plaque: the pathology of unstable coronary lesions,” J. Interv. Cardiol.15(6), 439–446 (2002).
[CrossRef] [PubMed]

J. Microsc.

M. S. Nguyen, O. Salvado, D. Roy, G. Steyer, M. E. Stone, R. D. Hoffman, and D. L. Wilson, “Ex vivo characterization of human atherosclerotic iliac plaque components using cryo-imaging,” J. Microsc.232(3), 432–441 (2008).
[CrossRef] [PubMed]

JACC Cardiovasc. Interv.

Y. Ino, T. Kubo, A. Tanaka, A. Kuroi, H. Tsujioka, H. Ikejima, K. Okouchi, M. Kashiwagi, S. Takarada, H. Kitabata, T. Tanimoto, K. Komukai, K. Ishibashi, K. Kimura, K. Hirata, M. Mizukoshi, T. Imanishi, and T. Akasaka, “Difference of culprit lesion morphologies between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study,” JACC Cardiovasc. Interv.4(1), 76–82 (2011).
[CrossRef] [PubMed]

H. G. Bezerra, M. A. Costa, G. Guagliumi, A. M. Rollins, and D. I. Simon, “Intracoronary optical coherence tomography: a comprehensive review clinical and research applications,” JACC Cardiovasc. Interv.2(11), 1035–1046 (2009).
[CrossRef] [PubMed]

N. Engl. J. Med.

A. P. Burke, A. Farb, G. T. Malcom, Y. H. Liang, J. Smialek, and R. Virmani, “Coronary risk factors and plaque morphology in men with coronary disease who died suddenly,” N. Engl. J. Med.336(18), 1276–1282 (1997).
[CrossRef] [PubMed]

Proc. Natl. Acad. Sci. U.S.A.

Y. Vengrenyuk, S. Carlier, S. Xanthos, L. Cardoso, P. Ganatos, R. Virmani, S. Einav, L. Gilchrist, and S. Weinbaum, “A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps,” Proc. Natl. Acad. Sci. U.S.A.103(40), 14678–14683 (2006).
[CrossRef] [PubMed]

Proc. SPIE

Z. Wang, H. Kyono, H. Bezerra, D. Wilson, M. Costa, and A. Rollins, “Automatic segmentation of intravascular optical coherence tomography images for facilitating quantitative diagnosis of atherosclerosis,” Proc. SPIE7889, 78890N (2011).
[CrossRef]

Science

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Other

T. H. Cormen, C. E. Leiserson, R. L. Rivest, and C. Stein, Introduction to Algorithms (MIT Press, 2001).

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (8)

Fig. 1
Fig. 1

Guide wire and lumen segmentation. (a) OCT image in polar coordinates. The guide wire has a high reflection followed by a long dark shadow. The average intensity of each A line was computed and the 2D image became a single line illustrated as the dotted line in (b). (b) The guide wire region became a continuous dark band traversing the whole pullback after the average intensity of each frame was combined into a single longitudinal image. Dynamic programming was performed on this image to extract the two boundaries of the guide wire shadow. (c) Corresponding anatomical view OCT image of (a). (d) Lumen segmentation using the dynamic programming algorithm.

Fig. 2
Fig. 2

Methodology for validation of fibrous cap luminal and abluminal boundary determination. The distance from the two boundaries to the lumen centroid was defined as d_L B i and d_AL B i , respectively, and compared between the computer algorithm and human analysts. This distance was calculated along rays at intervals of one degree.

Fig. 3
Fig. 3

Manual measurements of the minimum cap thickness of the 14 lesions by the three analysts. (a): The difference of the selected frame for measuring the minimum cap thickness by the three analysts was plotted vs. the lesion number. The frame difference is against analyst 1. Frame difference of 0 indicates no difference. (b): The minimum cap thickness measured on the selected frame in (a). CCC: concordance correlation coefficient. CCC<0.4 is considered to be poor agreement. Dashed line: conventional cut-off value of 65 µm for definition of TCFA. Under this definition, one of the three analysts held a different assessment of TCFA for 10 out of 14 lesions.

Fig. 4
Fig. 4

(a): Mean absolute difference (MAD) between automated and manual measurements by three observers. (b): Mean signed difference (MSD). Left: fibrous cap thickness determination. Middle: Luminal boundary determination. Right: Abluminal boundary determination. O: observer. Auto: computer algorithm.

Fig. 5
Fig. 5

In this case, the semi-automatically segmented fibrous cap boundary showed good agreement with all three human analysts.

Fig. 6
Fig. 6

In this case, the algorithm shows disagreement with the 3 analysts. The traced FC from analyst 2 is significantly thinner than that from the algorithm. In comparison, the FC traced by analyst 3 around 9-10 o’clock is significantly thicker. Analyst 1 selected more circumferential distribution of FC for segmentation.

Fig. 7
Fig. 7

Two coronary arteries used in the validation study with fibrous caps (FC) rendered in a continuous color map indicating the thickness. Both of the two lesions contain TCFA (red arrows) and similar minimum cap thickness. However, the one shown in the lower panel contains a significantly larger surface area with thin cap as compared to the one in the upper panel.

Fig. 8
Fig. 8

In this case, the computer algorithm mistakenly identified luminal blood as part of the tissue due to the contact between the blood and lumen boundary. In the blood-free region, the algorithm accurately segmented the boundary as compared to human analysts.

Tables (1)

Tables Icon

Table 1 Correlation coefficients between the volumetric metrics in 14 lesionsa

Equations (4)

Equations on this page are rendered with MathJax. Learn more.

C(i,j)= max jnj*j+n { C(i1,j*)+f(i,j) }        θ A <i θ B C(i,j)=f(i,j)                                                i= θ A
f_lumen(i,j)= I ¯ (i,j j α j+ m v ) I ¯ (i,j m l < j α <j)
f_FC(i,j)= I ¯ (i,j d l j α j) I ¯ (i,j< j α d max )λμ
MA D LB = 1 n i=1 n | d_L B i Manual d_L B i Auto |      MA D ALB = 1 n i=1 n | d_AL B i Manual d_AL B i Auto |

Metrics