Abstract

We investigated the wavelength dependence of imaging depth and clearness of structure in ultrahigh-resolution optical coherence tomography over a wide wavelength range. We quantitatively compared the optical properties of samples using supercontinuum sources at five wavelengths, 800 nm, 1060 nm, 1300 nm, 1550 nm, and 1700 nm, with the same system architecture. For samples of industrially used homogeneous materials with low water absorption, the attenuation coefficients of the samples were fitted using Rayleigh scattering theory. We confirmed that the systems with the longer-wavelength sources had lower scattering coefficients and less dependence on the sample materials. For a biomedical sample, we observed wavelength dependence of the attenuation coefficient, which can be explained by absorption by water and hemoglobin.

© 2012 OSA

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2011 (1)

S. Ishida, N. Nishizawa, T. Ohta, and K. Itoh, “Ultrahigh-resolution optical coherence tomography in 1.7 μm region with fiber laser supercontinuum in low water absorption samples,” Appl. Phys. Express4(5), 052501 (2011).
[CrossRef]

2010 (2)

V. M. Kodach, J. Kalkman, D. J. Faber, and T. G. van Leeuwen, “Quantitative comparison of the OCT imaging depth at 1300 nm and 1600 nm,” Biomed. Opt. Express1(1), 176–185 (2010).
[CrossRef] [PubMed]

M. Nishiura, T. Kobayashi, M. Adachi, J. Nakanishi, T. Ueno, Y. Ito, and N. Nishizawa, “In vivo ultrahigh-resolution ophthalmic optical coherence tomography using Gaussian-shaped supercontinuum,” Jpn. J. Appl. Phys.49(1), 012701 (2010).
[CrossRef]

2008 (1)

2007 (1)

A. M. Zysk, F. T. Nguyen, A. L. Oldenburg, D. L. Marks, and S. A. Boppart, “Optical coherence tomography: a review of clinical development from bench to bedside,” J. Biomed. Opt.12(5), 051403 (2007).
[CrossRef] [PubMed]

2006 (3)

R. A. Costa, M. Skaf, L. A. S. Melo, D. Calucci, J. A. Cardillo, J. C. Castro, D. Huang, and M. Wojtkowski, “Retinal assessment using optical coherence tomography,” Prog. Retin. Eye Res.25(3), 325–353 (2006).
[CrossRef] [PubMed]

A. Z. Freitas, D. M. Zezell, N. D. Vieira, A. C. Ribeiro, and A. S. L. Gomes, “Imaging carious human dental tissue with optical coherence tomography,” J. Appl. Phys.99(2), 024906 (2006).
[CrossRef]

A. Aguirre, N. Nishizawa, J. G. Fujimoto, W. Seitz, M. Lederer, and D. Kopf, “Continuum generation in a novel photonic crystal fiber for ultrahigh resolution optical coherence tomography at 800 nm and 1300 nm,” Opt. Express14(3), 1145–1160 (2006).
[CrossRef] [PubMed]

2005 (2)

A. F. Zuluaga, M. Follen, I. Boiko, A. Malpica, and R. Richards-Kortum, “Optical coherence tomography: a pilot study of a new imaging technique for noninvasive examination of cervical tissue,” Am. J. Obstet. Gynecol.193(1), 83–88 (2005).
[CrossRef] [PubMed]

M. Mujat, R. C. Chan, B. Cense, B. H. Park, C. Joo, T. Akkin, T. C. Chen, and J. F. de Boer, “Retinal nerve fiber layer thickness map determined from optical coherence tomography images,” Opt. Express13(23), 9480–9491 (2005).
[CrossRef] [PubMed]

2004 (3)

2003 (2)

S. Bourquin, A. D. Aguirre, I. Hartl, P. Hsiung, T. H. Ko, J. G. Fujimoto, T. A. Birks, W. J. Wadsworth, U. Bünting, and D. Kopf, “Ultrahigh resolution real time OCT imaging using a compact femtosecond Nd:glass laser and nonlinear fiber,” Opt. Express11(24), 3290–3297 (2003).
[CrossRef] [PubMed]

G. J. Tearney, H. Yabushita, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, E. F. Halpern, and B. E. Bouma, “Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography,” Circulation107(1), 113–119 (2003).
[CrossRef] [PubMed]

2002 (1)

B. E. Bouma and G. J. Tearney, “Clinical imaging with optical coherence tomography,” Acad. Radiol.9(8), 942–953 (2002).
[CrossRef] [PubMed]

2001 (1)

S. Radhakrishnan, A. M. Rollins, J. E. Roth, S. Yazdanfar, V. Westphal, D. S. Bardenstein, and J. A. Izatt, “Real-time optical coherence tomography of the anterior segment at 1310 nm,” Arch. Ophthalmol.119(8), 1179–1185 (2001).
[PubMed]

2000 (1)

L. L. Otis, B. W. Colston, M. J. Everett, and H. Nathel, “Dental optical coherence tomography: a comparison of two in vitro systems,” Dentomaxillofac. Radiol.29(2), 85–89 (2000).
[CrossRef] [PubMed]

1999 (2)

J. G. Fujimoto, S. A. Boppart, G. J. Tearney, B. E. Bouma, C. Pitris, and M. E. Brezinski, “High resolution in vivo intra-arterial imaging with optical coherence tomography,” Heart82(2), 128–133 (1999).
[PubMed]

J. M. Schmitt, “Optical coherence tomography (OCT): a review,” IEEE J. Sel. Top. Quantum Electron.5(4), 1205–1215 (1999).
[CrossRef]

1998 (2)

Y. Pan and D. L. Farkas, “Nonivasive imaging of living human skin with dual-wavelength optical coherence tomography in two and three dimensions,” J. Biomed. Opt.3(4), 446–455 (1998).
[CrossRef]

B. W. Colston, M. J. Everett, L. B. Da Silva, L. L. Otis, P. Stroeve, and H. Nathel, “Imaging of hard- and soft-tissue structure in the oral cavity by optical coherence tomography,” Appl. Opt.37(16), 3582–3585 (1998).
[CrossRef] [PubMed]

1994 (1)

J. M. Schmitt, A. Knüttel, M. Yadlowsky, and M. A. Eckhaus, “Optical-coherence tomography of a dense tissue: statistics of attenuation and backscattering,” Phys. Med. Biol.39(10), 1705–1720 (1994).
[CrossRef] [PubMed]

1993 (1)

1991 (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

1973 (1)

Aalders, M. C. G.

Adachi, M.

M. Nishiura, T. Kobayashi, M. Adachi, J. Nakanishi, T. Ueno, Y. Ito, and N. Nishizawa, “In vivo ultrahigh-resolution ophthalmic optical coherence tomography using Gaussian-shaped supercontinuum,” Jpn. J. Appl. Phys.49(1), 012701 (2010).
[CrossRef]

Aguirre, A.

Aguirre, A. D.

Akkin, T.

Aretz, H. T.

G. J. Tearney, H. Yabushita, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, E. F. Halpern, and B. E. Bouma, “Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography,” Circulation107(1), 113–119 (2003).
[CrossRef] [PubMed]

Bardenstein, D. S.

S. Radhakrishnan, A. M. Rollins, J. E. Roth, S. Yazdanfar, V. Westphal, D. S. Bardenstein, and J. A. Izatt, “Real-time optical coherence tomography of the anterior segment at 1310 nm,” Arch. Ophthalmol.119(8), 1179–1185 (2001).
[PubMed]

Birks, T. A.

Boiko, I.

A. F. Zuluaga, M. Follen, I. Boiko, A. Malpica, and R. Richards-Kortum, “Optical coherence tomography: a pilot study of a new imaging technique for noninvasive examination of cervical tissue,” Am. J. Obstet. Gynecol.193(1), 83–88 (2005).
[CrossRef] [PubMed]

Bonner, R. F.

Boppart, S. A.

A. M. Zysk, F. T. Nguyen, A. L. Oldenburg, D. L. Marks, and S. A. Boppart, “Optical coherence tomography: a review of clinical development from bench to bedside,” J. Biomed. Opt.12(5), 051403 (2007).
[CrossRef] [PubMed]

S. A. Boppart, W. Luo, D. L. Marks, and K. W. Singletary, “Optical coherence tomography: feasibility for basic research and image-guided surgery of breast cancer,” Breast Cancer Res. Treat.84(2), 85–97 (2004).
[CrossRef] [PubMed]

J. G. Fujimoto, S. A. Boppart, G. J. Tearney, B. E. Bouma, C. Pitris, and M. E. Brezinski, “High resolution in vivo intra-arterial imaging with optical coherence tomography,” Heart82(2), 128–133 (1999).
[PubMed]

Bouma, B. E.

G. J. Tearney, H. Yabushita, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, E. F. Halpern, and B. E. Bouma, “Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography,” Circulation107(1), 113–119 (2003).
[CrossRef] [PubMed]

B. E. Bouma and G. J. Tearney, “Clinical imaging with optical coherence tomography,” Acad. Radiol.9(8), 942–953 (2002).
[CrossRef] [PubMed]

J. G. Fujimoto, S. A. Boppart, G. J. Tearney, B. E. Bouma, C. Pitris, and M. E. Brezinski, “High resolution in vivo intra-arterial imaging with optical coherence tomography,” Heart82(2), 128–133 (1999).
[PubMed]

Bourquin, S.

Brezinski, M. E.

J. G. Fujimoto, S. A. Boppart, G. J. Tearney, B. E. Bouma, C. Pitris, and M. E. Brezinski, “High resolution in vivo intra-arterial imaging with optical coherence tomography,” Heart82(2), 128–133 (1999).
[PubMed]

Bünting, U.

Calucci, D.

R. A. Costa, M. Skaf, L. A. S. Melo, D. Calucci, J. A. Cardillo, J. C. Castro, D. Huang, and M. Wojtkowski, “Retinal assessment using optical coherence tomography,” Prog. Retin. Eye Res.25(3), 325–353 (2006).
[CrossRef] [PubMed]

Cardillo, J. A.

R. A. Costa, M. Skaf, L. A. S. Melo, D. Calucci, J. A. Cardillo, J. C. Castro, D. Huang, and M. Wojtkowski, “Retinal assessment using optical coherence tomography,” Prog. Retin. Eye Res.25(3), 325–353 (2006).
[CrossRef] [PubMed]

Castro, J. C.

R. A. Costa, M. Skaf, L. A. S. Melo, D. Calucci, J. A. Cardillo, J. C. Castro, D. Huang, and M. Wojtkowski, “Retinal assessment using optical coherence tomography,” Prog. Retin. Eye Res.25(3), 325–353 (2006).
[CrossRef] [PubMed]

Cense, B.

Chan, R. C.

Chang, E. W.

Chang, W.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Chen, T. C.

Chen, Y.

Colston, B. W.

L. L. Otis, B. W. Colston, M. J. Everett, and H. Nathel, “Dental optical coherence tomography: a comparison of two in vitro systems,” Dentomaxillofac. Radiol.29(2), 85–89 (2000).
[CrossRef] [PubMed]

B. W. Colston, M. J. Everett, L. B. Da Silva, L. L. Otis, P. Stroeve, and H. Nathel, “Imaging of hard- and soft-tissue structure in the oral cavity by optical coherence tomography,” Appl. Opt.37(16), 3582–3585 (1998).
[CrossRef] [PubMed]

Costa, R. A.

R. A. Costa, M. Skaf, L. A. S. Melo, D. Calucci, J. A. Cardillo, J. C. Castro, D. Huang, and M. Wojtkowski, “Retinal assessment using optical coherence tomography,” Prog. Retin. Eye Res.25(3), 325–353 (2006).
[CrossRef] [PubMed]

Da Silva, L. B.

de Boer, J. F.

Eckhaus, M. A.

J. M. Schmitt, A. Knüttel, M. Yadlowsky, and M. A. Eckhaus, “Optical-coherence tomography of a dense tissue: statistics of attenuation and backscattering,” Phys. Med. Biol.39(10), 1705–1720 (1994).
[CrossRef] [PubMed]

Everett, M. J.

L. L. Otis, B. W. Colston, M. J. Everett, and H. Nathel, “Dental optical coherence tomography: a comparison of two in vitro systems,” Dentomaxillofac. Radiol.29(2), 85–89 (2000).
[CrossRef] [PubMed]

B. W. Colston, M. J. Everett, L. B. Da Silva, L. L. Otis, P. Stroeve, and H. Nathel, “Imaging of hard- and soft-tissue structure in the oral cavity by optical coherence tomography,” Appl. Opt.37(16), 3582–3585 (1998).
[CrossRef] [PubMed]

Faber, D. J.

Farkas, D. L.

Y. Pan and D. L. Farkas, “Nonivasive imaging of living human skin with dual-wavelength optical coherence tomography in two and three dimensions,” J. Biomed. Opt.3(4), 446–455 (1998).
[CrossRef]

Flotte, T.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Follen, M.

A. F. Zuluaga, M. Follen, I. Boiko, A. Malpica, and R. Richards-Kortum, “Optical coherence tomography: a pilot study of a new imaging technique for noninvasive examination of cervical tissue,” Am. J. Obstet. Gynecol.193(1), 83–88 (2005).
[CrossRef] [PubMed]

Freitas, A. Z.

A. Z. Freitas, D. M. Zezell, N. D. Vieira, A. C. Ribeiro, and A. S. L. Gomes, “Imaging carious human dental tissue with optical coherence tomography,” J. Appl. Phys.99(2), 024906 (2006).
[CrossRef]

Fujimoto, J. G.

Gomes, A. S. L.

A. Z. Freitas, D. M. Zezell, N. D. Vieira, A. C. Ribeiro, and A. S. L. Gomes, “Imaging carious human dental tissue with optical coherence tomography,” J. Appl. Phys.99(2), 024906 (2006).
[CrossRef]

Gregory, K.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Hale, G. M.

Halpern, E. F.

G. J. Tearney, H. Yabushita, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, E. F. Halpern, and B. E. Bouma, “Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography,” Circulation107(1), 113–119 (2003).
[CrossRef] [PubMed]

Hartl, I.

Hee, M. R.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Houser, S. L.

G. J. Tearney, H. Yabushita, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, E. F. Halpern, and B. E. Bouma, “Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography,” Circulation107(1), 113–119 (2003).
[CrossRef] [PubMed]

Hsiung, P.

Huang, D.

R. A. Costa, M. Skaf, L. A. S. Melo, D. Calucci, J. A. Cardillo, J. C. Castro, D. Huang, and M. Wojtkowski, “Retinal assessment using optical coherence tomography,” Prog. Retin. Eye Res.25(3), 325–353 (2006).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Ippen, E. P.

Ishida, S.

S. Ishida, N. Nishizawa, T. Ohta, and K. Itoh, “Ultrahigh-resolution optical coherence tomography in 1.7 μm region with fiber laser supercontinuum in low water absorption samples,” Appl. Phys. Express4(5), 052501 (2011).
[CrossRef]

Ito, Y.

M. Nishiura, T. Kobayashi, M. Adachi, J. Nakanishi, T. Ueno, Y. Ito, and N. Nishizawa, “In vivo ultrahigh-resolution ophthalmic optical coherence tomography using Gaussian-shaped supercontinuum,” Jpn. J. Appl. Phys.49(1), 012701 (2010).
[CrossRef]

Itoh, K.

S. Ishida, N. Nishizawa, T. Ohta, and K. Itoh, “Ultrahigh-resolution optical coherence tomography in 1.7 μm region with fiber laser supercontinuum in low water absorption samples,” Appl. Phys. Express4(5), 052501 (2011).
[CrossRef]

Izatt, J. A.

S. Radhakrishnan, A. M. Rollins, J. E. Roth, S. Yazdanfar, V. Westphal, D. S. Bardenstein, and J. A. Izatt, “Real-time optical coherence tomography of the anterior segment at 1310 nm,” Arch. Ophthalmol.119(8), 1179–1185 (2001).
[PubMed]

Jang, I. K.

G. J. Tearney, H. Yabushita, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, E. F. Halpern, and B. E. Bouma, “Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography,” Circulation107(1), 113–119 (2003).
[CrossRef] [PubMed]

Joo, C.

Kalkman, J.

Kauffman, C. R.

G. J. Tearney, H. Yabushita, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, E. F. Halpern, and B. E. Bouma, “Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography,” Circulation107(1), 113–119 (2003).
[CrossRef] [PubMed]

Knüttel, A.

J. M. Schmitt, A. Knüttel, M. Yadlowsky, and M. A. Eckhaus, “Optical-coherence tomography of a dense tissue: statistics of attenuation and backscattering,” Phys. Med. Biol.39(10), 1705–1720 (1994).
[CrossRef] [PubMed]

J. M. Schmitt, A. Knüttel, and R. F. Bonner, “Measurement of optical properties of biological tissues by low-coherence reflectometry,” Appl. Opt.32(30), 6032–6042 (1993).
[CrossRef] [PubMed]

Ko, T. H.

Kobayashi, T.

M. Nishiura, T. Kobayashi, M. Adachi, J. Nakanishi, T. Ueno, Y. Ito, and N. Nishizawa, “In vivo ultrahigh-resolution ophthalmic optical coherence tomography using Gaussian-shaped supercontinuum,” Jpn. J. Appl. Phys.49(1), 012701 (2010).
[CrossRef]

Kodach, V. M.

Kopf, D.

Lederer, M.

Lin, C. P.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Luo, W.

S. A. Boppart, W. Luo, D. L. Marks, and K. W. Singletary, “Optical coherence tomography: feasibility for basic research and image-guided surgery of breast cancer,” Breast Cancer Res. Treat.84(2), 85–97 (2004).
[CrossRef] [PubMed]

Malpica, A.

A. F. Zuluaga, M. Follen, I. Boiko, A. Malpica, and R. Richards-Kortum, “Optical coherence tomography: a pilot study of a new imaging technique for noninvasive examination of cervical tissue,” Am. J. Obstet. Gynecol.193(1), 83–88 (2005).
[CrossRef] [PubMed]

Marks, D. L.

A. M. Zysk, F. T. Nguyen, A. L. Oldenburg, D. L. Marks, and S. A. Boppart, “Optical coherence tomography: a review of clinical development from bench to bedside,” J. Biomed. Opt.12(5), 051403 (2007).
[CrossRef] [PubMed]

S. A. Boppart, W. Luo, D. L. Marks, and K. W. Singletary, “Optical coherence tomography: feasibility for basic research and image-guided surgery of breast cancer,” Breast Cancer Res. Treat.84(2), 85–97 (2004).
[CrossRef] [PubMed]

Melo, L. A. S.

R. A. Costa, M. Skaf, L. A. S. Melo, D. Calucci, J. A. Cardillo, J. C. Castro, D. Huang, and M. Wojtkowski, “Retinal assessment using optical coherence tomography,” Prog. Retin. Eye Res.25(3), 325–353 (2006).
[CrossRef] [PubMed]

Mujat, M.

Nakanishi, J.

M. Nishiura, T. Kobayashi, M. Adachi, J. Nakanishi, T. Ueno, Y. Ito, and N. Nishizawa, “In vivo ultrahigh-resolution ophthalmic optical coherence tomography using Gaussian-shaped supercontinuum,” Jpn. J. Appl. Phys.49(1), 012701 (2010).
[CrossRef]

Nathel, H.

L. L. Otis, B. W. Colston, M. J. Everett, and H. Nathel, “Dental optical coherence tomography: a comparison of two in vitro systems,” Dentomaxillofac. Radiol.29(2), 85–89 (2000).
[CrossRef] [PubMed]

B. W. Colston, M. J. Everett, L. B. Da Silva, L. L. Otis, P. Stroeve, and H. Nathel, “Imaging of hard- and soft-tissue structure in the oral cavity by optical coherence tomography,” Appl. Opt.37(16), 3582–3585 (1998).
[CrossRef] [PubMed]

Nguyen, F. T.

A. M. Zysk, F. T. Nguyen, A. L. Oldenburg, D. L. Marks, and S. A. Boppart, “Optical coherence tomography: a review of clinical development from bench to bedside,” J. Biomed. Opt.12(5), 051403 (2007).
[CrossRef] [PubMed]

Nishiura, M.

M. Nishiura, T. Kobayashi, M. Adachi, J. Nakanishi, T. Ueno, Y. Ito, and N. Nishizawa, “In vivo ultrahigh-resolution ophthalmic optical coherence tomography using Gaussian-shaped supercontinuum,” Jpn. J. Appl. Phys.49(1), 012701 (2010).
[CrossRef]

Nishizawa, N.

S. Ishida, N. Nishizawa, T. Ohta, and K. Itoh, “Ultrahigh-resolution optical coherence tomography in 1.7 μm region with fiber laser supercontinuum in low water absorption samples,” Appl. Phys. Express4(5), 052501 (2011).
[CrossRef]

M. Nishiura, T. Kobayashi, M. Adachi, J. Nakanishi, T. Ueno, Y. Ito, and N. Nishizawa, “In vivo ultrahigh-resolution ophthalmic optical coherence tomography using Gaussian-shaped supercontinuum,” Jpn. J. Appl. Phys.49(1), 012701 (2010).
[CrossRef]

A. Aguirre, N. Nishizawa, J. G. Fujimoto, W. Seitz, M. Lederer, and D. Kopf, “Continuum generation in a novel photonic crystal fiber for ultrahigh resolution optical coherence tomography at 800 nm and 1300 nm,” Opt. Express14(3), 1145–1160 (2006).
[CrossRef] [PubMed]

N. Nishizawa, Y. Chen, P. Hsiung, E. P. Ippen, and J. G. Fujimoto, “Real-time, ultrahigh-resolution, optical coherence tomography with an all-fiber, femtosecond fiber laser continuum at 1.5 microm,” Opt. Lett.29(24), 2846–2848 (2004).
[CrossRef] [PubMed]

Ohta, T.

S. Ishida, N. Nishizawa, T. Ohta, and K. Itoh, “Ultrahigh-resolution optical coherence tomography in 1.7 μm region with fiber laser supercontinuum in low water absorption samples,” Appl. Phys. Express4(5), 052501 (2011).
[CrossRef]

Oldenburg, A. L.

A. M. Zysk, F. T. Nguyen, A. L. Oldenburg, D. L. Marks, and S. A. Boppart, “Optical coherence tomography: a review of clinical development from bench to bedside,” J. Biomed. Opt.12(5), 051403 (2007).
[CrossRef] [PubMed]

Otis, L. L.

L. L. Otis, B. W. Colston, M. J. Everett, and H. Nathel, “Dental optical coherence tomography: a comparison of two in vitro systems,” Dentomaxillofac. Radiol.29(2), 85–89 (2000).
[CrossRef] [PubMed]

B. W. Colston, M. J. Everett, L. B. Da Silva, L. L. Otis, P. Stroeve, and H. Nathel, “Imaging of hard- and soft-tissue structure in the oral cavity by optical coherence tomography,” Appl. Opt.37(16), 3582–3585 (1998).
[CrossRef] [PubMed]

Pan, Y.

Y. Pan and D. L. Farkas, “Nonivasive imaging of living human skin with dual-wavelength optical coherence tomography in two and three dimensions,” J. Biomed. Opt.3(4), 446–455 (1998).
[CrossRef]

Park, B. H.

Pitris, C.

J. G. Fujimoto, S. A. Boppart, G. J. Tearney, B. E. Bouma, C. Pitris, and M. E. Brezinski, “High resolution in vivo intra-arterial imaging with optical coherence tomography,” Heart82(2), 128–133 (1999).
[PubMed]

Puliafito, C. A.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Querry, M. R.

Radhakrishnan, S.

S. Radhakrishnan, A. M. Rollins, J. E. Roth, S. Yazdanfar, V. Westphal, D. S. Bardenstein, and J. A. Izatt, “Real-time optical coherence tomography of the anterior segment at 1310 nm,” Arch. Ophthalmol.119(8), 1179–1185 (2001).
[PubMed]

Ribeiro, A. C.

A. Z. Freitas, D. M. Zezell, N. D. Vieira, A. C. Ribeiro, and A. S. L. Gomes, “Imaging carious human dental tissue with optical coherence tomography,” J. Appl. Phys.99(2), 024906 (2006).
[CrossRef]

Richards-Kortum, R.

A. F. Zuluaga, M. Follen, I. Boiko, A. Malpica, and R. Richards-Kortum, “Optical coherence tomography: a pilot study of a new imaging technique for noninvasive examination of cervical tissue,” Am. J. Obstet. Gynecol.193(1), 83–88 (2005).
[CrossRef] [PubMed]

Rollins, A. M.

S. Radhakrishnan, A. M. Rollins, J. E. Roth, S. Yazdanfar, V. Westphal, D. S. Bardenstein, and J. A. Izatt, “Real-time optical coherence tomography of the anterior segment at 1310 nm,” Arch. Ophthalmol.119(8), 1179–1185 (2001).
[PubMed]

Roth, J. E.

S. Radhakrishnan, A. M. Rollins, J. E. Roth, S. Yazdanfar, V. Westphal, D. S. Bardenstein, and J. A. Izatt, “Real-time optical coherence tomography of the anterior segment at 1310 nm,” Arch. Ophthalmol.119(8), 1179–1185 (2001).
[PubMed]

Schlendorf, K. H.

G. J. Tearney, H. Yabushita, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, E. F. Halpern, and B. E. Bouma, “Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography,” Circulation107(1), 113–119 (2003).
[CrossRef] [PubMed]

Schmitt, J. M.

J. M. Schmitt, “Optical coherence tomography (OCT): a review,” IEEE J. Sel. Top. Quantum Electron.5(4), 1205–1215 (1999).
[CrossRef]

J. M. Schmitt, A. Knüttel, M. Yadlowsky, and M. A. Eckhaus, “Optical-coherence tomography of a dense tissue: statistics of attenuation and backscattering,” Phys. Med. Biol.39(10), 1705–1720 (1994).
[CrossRef] [PubMed]

J. M. Schmitt, A. Knüttel, and R. F. Bonner, “Measurement of optical properties of biological tissues by low-coherence reflectometry,” Appl. Opt.32(30), 6032–6042 (1993).
[CrossRef] [PubMed]

Schuman, J. S.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Seitz, W.

Sharma, U.

Shishkov, M.

G. J. Tearney, H. Yabushita, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, E. F. Halpern, and B. E. Bouma, “Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography,” Circulation107(1), 113–119 (2003).
[CrossRef] [PubMed]

Singletary, K. W.

S. A. Boppart, W. Luo, D. L. Marks, and K. W. Singletary, “Optical coherence tomography: feasibility for basic research and image-guided surgery of breast cancer,” Breast Cancer Res. Treat.84(2), 85–97 (2004).
[CrossRef] [PubMed]

Skaf, M.

R. A. Costa, M. Skaf, L. A. S. Melo, D. Calucci, J. A. Cardillo, J. C. Castro, D. Huang, and M. Wojtkowski, “Retinal assessment using optical coherence tomography,” Prog. Retin. Eye Res.25(3), 325–353 (2006).
[CrossRef] [PubMed]

Stinson, W. G.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Stroeve, P.

Swanson, E. A.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Tearney, G. J.

G. J. Tearney, H. Yabushita, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, E. F. Halpern, and B. E. Bouma, “Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography,” Circulation107(1), 113–119 (2003).
[CrossRef] [PubMed]

B. E. Bouma and G. J. Tearney, “Clinical imaging with optical coherence tomography,” Acad. Radiol.9(8), 942–953 (2002).
[CrossRef] [PubMed]

J. G. Fujimoto, S. A. Boppart, G. J. Tearney, B. E. Bouma, C. Pitris, and M. E. Brezinski, “High resolution in vivo intra-arterial imaging with optical coherence tomography,” Heart82(2), 128–133 (1999).
[PubMed]

Ueno, T.

M. Nishiura, T. Kobayashi, M. Adachi, J. Nakanishi, T. Ueno, Y. Ito, and N. Nishizawa, “In vivo ultrahigh-resolution ophthalmic optical coherence tomography using Gaussian-shaped supercontinuum,” Jpn. J. Appl. Phys.49(1), 012701 (2010).
[CrossRef]

van der Meer, F. J.

van Leeuwen, T.

van Leeuwen, T. G.

Vieira, N. D.

A. Z. Freitas, D. M. Zezell, N. D. Vieira, A. C. Ribeiro, and A. S. L. Gomes, “Imaging carious human dental tissue with optical coherence tomography,” J. Appl. Phys.99(2), 024906 (2006).
[CrossRef]

Wadsworth, W. J.

Westphal, V.

S. Radhakrishnan, A. M. Rollins, J. E. Roth, S. Yazdanfar, V. Westphal, D. S. Bardenstein, and J. A. Izatt, “Real-time optical coherence tomography of the anterior segment at 1310 nm,” Arch. Ophthalmol.119(8), 1179–1185 (2001).
[PubMed]

Wojtkowski, M.

R. A. Costa, M. Skaf, L. A. S. Melo, D. Calucci, J. A. Cardillo, J. C. Castro, D. Huang, and M. Wojtkowski, “Retinal assessment using optical coherence tomography,” Prog. Retin. Eye Res.25(3), 325–353 (2006).
[CrossRef] [PubMed]

Yabushita, H.

G. J. Tearney, H. Yabushita, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, E. F. Halpern, and B. E. Bouma, “Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography,” Circulation107(1), 113–119 (2003).
[CrossRef] [PubMed]

Yadlowsky, M.

J. M. Schmitt, A. Knüttel, M. Yadlowsky, and M. A. Eckhaus, “Optical-coherence tomography of a dense tissue: statistics of attenuation and backscattering,” Phys. Med. Biol.39(10), 1705–1720 (1994).
[CrossRef] [PubMed]

Yazdanfar, S.

S. Radhakrishnan, A. M. Rollins, J. E. Roth, S. Yazdanfar, V. Westphal, D. S. Bardenstein, and J. A. Izatt, “Real-time optical coherence tomography of the anterior segment at 1310 nm,” Arch. Ophthalmol.119(8), 1179–1185 (2001).
[PubMed]

Yun, S. H.

Zezell, D. M.

A. Z. Freitas, D. M. Zezell, N. D. Vieira, A. C. Ribeiro, and A. S. L. Gomes, “Imaging carious human dental tissue with optical coherence tomography,” J. Appl. Phys.99(2), 024906 (2006).
[CrossRef]

Zuluaga, A. F.

A. F. Zuluaga, M. Follen, I. Boiko, A. Malpica, and R. Richards-Kortum, “Optical coherence tomography: a pilot study of a new imaging technique for noninvasive examination of cervical tissue,” Am. J. Obstet. Gynecol.193(1), 83–88 (2005).
[CrossRef] [PubMed]

Zysk, A. M.

A. M. Zysk, F. T. Nguyen, A. L. Oldenburg, D. L. Marks, and S. A. Boppart, “Optical coherence tomography: a review of clinical development from bench to bedside,” J. Biomed. Opt.12(5), 051403 (2007).
[CrossRef] [PubMed]

Acad. Radiol. (1)

B. E. Bouma and G. J. Tearney, “Clinical imaging with optical coherence tomography,” Acad. Radiol.9(8), 942–953 (2002).
[CrossRef] [PubMed]

Am. J. Obstet. Gynecol. (1)

A. F. Zuluaga, M. Follen, I. Boiko, A. Malpica, and R. Richards-Kortum, “Optical coherence tomography: a pilot study of a new imaging technique for noninvasive examination of cervical tissue,” Am. J. Obstet. Gynecol.193(1), 83–88 (2005).
[CrossRef] [PubMed]

Appl. Opt. (3)

Appl. Phys. Express (1)

S. Ishida, N. Nishizawa, T. Ohta, and K. Itoh, “Ultrahigh-resolution optical coherence tomography in 1.7 μm region with fiber laser supercontinuum in low water absorption samples,” Appl. Phys. Express4(5), 052501 (2011).
[CrossRef]

Arch. Ophthalmol. (1)

S. Radhakrishnan, A. M. Rollins, J. E. Roth, S. Yazdanfar, V. Westphal, D. S. Bardenstein, and J. A. Izatt, “Real-time optical coherence tomography of the anterior segment at 1310 nm,” Arch. Ophthalmol.119(8), 1179–1185 (2001).
[PubMed]

Biomed. Opt. Express (1)

Breast Cancer Res. Treat. (1)

S. A. Boppart, W. Luo, D. L. Marks, and K. W. Singletary, “Optical coherence tomography: feasibility for basic research and image-guided surgery of breast cancer,” Breast Cancer Res. Treat.84(2), 85–97 (2004).
[CrossRef] [PubMed]

Circulation (1)

G. J. Tearney, H. Yabushita, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, E. F. Halpern, and B. E. Bouma, “Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography,” Circulation107(1), 113–119 (2003).
[CrossRef] [PubMed]

Dentomaxillofac. Radiol. (1)

L. L. Otis, B. W. Colston, M. J. Everett, and H. Nathel, “Dental optical coherence tomography: a comparison of two in vitro systems,” Dentomaxillofac. Radiol.29(2), 85–89 (2000).
[CrossRef] [PubMed]

Heart (1)

J. G. Fujimoto, S. A. Boppart, G. J. Tearney, B. E. Bouma, C. Pitris, and M. E. Brezinski, “High resolution in vivo intra-arterial imaging with optical coherence tomography,” Heart82(2), 128–133 (1999).
[PubMed]

IEEE J. Sel. Top. Quantum Electron. (1)

J. M. Schmitt, “Optical coherence tomography (OCT): a review,” IEEE J. Sel. Top. Quantum Electron.5(4), 1205–1215 (1999).
[CrossRef]

J. Appl. Phys. (1)

A. Z. Freitas, D. M. Zezell, N. D. Vieira, A. C. Ribeiro, and A. S. L. Gomes, “Imaging carious human dental tissue with optical coherence tomography,” J. Appl. Phys.99(2), 024906 (2006).
[CrossRef]

J. Biomed. Opt. (2)

Y. Pan and D. L. Farkas, “Nonivasive imaging of living human skin with dual-wavelength optical coherence tomography in two and three dimensions,” J. Biomed. Opt.3(4), 446–455 (1998).
[CrossRef]

A. M. Zysk, F. T. Nguyen, A. L. Oldenburg, D. L. Marks, and S. A. Boppart, “Optical coherence tomography: a review of clinical development from bench to bedside,” J. Biomed. Opt.12(5), 051403 (2007).
[CrossRef] [PubMed]

Jpn. J. Appl. Phys. (1)

M. Nishiura, T. Kobayashi, M. Adachi, J. Nakanishi, T. Ueno, Y. Ito, and N. Nishizawa, “In vivo ultrahigh-resolution ophthalmic optical coherence tomography using Gaussian-shaped supercontinuum,” Jpn. J. Appl. Phys.49(1), 012701 (2010).
[CrossRef]

Opt. Express (5)

Opt. Lett. (1)

Phys. Med. Biol. (1)

J. M. Schmitt, A. Knüttel, M. Yadlowsky, and M. A. Eckhaus, “Optical-coherence tomography of a dense tissue: statistics of attenuation and backscattering,” Phys. Med. Biol.39(10), 1705–1720 (1994).
[CrossRef] [PubMed]

Prog. Retin. Eye Res. (1)

R. A. Costa, M. Skaf, L. A. S. Melo, D. Calucci, J. A. Cardillo, J. C. Castro, D. Huang, and M. Wojtkowski, “Retinal assessment using optical coherence tomography,” Prog. Retin. Eye Res.25(3), 325–353 (2006).
[CrossRef] [PubMed]

Science (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991).
[CrossRef] [PubMed]

Other (2)

B. E. Bouma and G. J. Tearney, Handbook of Optical Coherence Tomography (Informa Healthcare, New York, 2001).

S. Prahl, “Optical absorption of hemoglobin” (Oregon Medical Laser Center, Portland, Oreg., September 22, 2010), http://omlc.ogi.edu/spectra/hemoglobin/ .

Supplementary Material (2)

» Media 1: MOV (3224 KB)     
» Media 2: MOV (3741 KB)     

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Figures (11)

Fig. 1
Fig. 1

(a) Output spectra of supercontinuum sources together with water absorption spectrum and (b) corresponding theoretical longitudinal resolutions at all wavelengths as a function of bandwidth.

Fig. 2
Fig. 2

Experimental setup for time-domain optical coherence tomography.

Fig. 3
Fig. 3

(a–e) Interference signals with mirror as sample at (a) 800 nm, (b) 1060 nm, (c) 1300 nm, (d) 1550 nm, and (e) 1700 nm UHR-OCT in air. (f) Observed longitudinal resolutions (circles) together with theoretical predictions (solid lines).

Fig. 4
Fig. 4

Observed spatial beam profiles at the top of surface of the sample at all wavelengths.

Fig. 5
Fig. 5

(a) Photograph of semiconductor memory card with plastic cover. (b, c) OCT images obtained at (b) 0.8 μm and (c) 1.7 μm. (d–h) Depth profiles averaged over 250 A-line scans and more than 50 iterative measurements at (d) 800 nm, (e) 1060 nm, (f) 1300 nm, (g) 1550 nm, and (h) 1700 nm. The slopes shown by the red lines were used to determine the total attenuation coefficients.

Fig. 6
Fig. 6

(a) Photograph of eraser. (b–f) Depth profiles averaged over 250 A-lines and more than 50 iterative measurements at (b) 800 nm, (c) 1060 nm, (d) 1300 nm, (e) 1550 nm, and (f) 1700 nm. The slopes shown by the red lines were used to determine the total attenuation coefficients.

Fig. 7
Fig. 7

(a) Photograph of magnet. (b–f) Depth profiles averaged over 250 A-lines and more than 50 iterative measurements at (b) 800 nm, (c) 1060 nm, (d) 1300 nm, (e) 1550 nm, and (f) 1700 nm. The slopes shown by the red lines were used to determine the total attenuation coefficients.

Fig. 8
Fig. 8

Wavelength dependence of total attenuation coefficient for industrially used materials

Fig. 9
Fig. 9

(a) Photograph of human tooth sample. (b–f) OCT images at red line in (a) and depth profiles obtained at red dashed line in each of the OCT images at (b) 800 nm, (c) 1060 nm, (d) 1300 nm, (e) 1550 nm, and (f) 1700 nm. The slopes shown by the red and blue solid lines were used to determine the total attenuation coefficients. (g) Wavelength dependence of total attenuation coefficients of enamel and dentine layers in the sample. Important features inside the sample can be distinguished, such as the enamel layer (en) and the dentin layer (d).

Fig. 10
Fig. 10

(a) Photograph of pig trachea sample. (b–f) OCT images and depth profiles at the red dashed line in each OCT image at (b) 800 nm, (c) 1060 nm, (d) 1300 nm, (e) 1550 nm and (f) 1700 nm . The slopes shown by the solid red lines were used to determine the total attenuation coefficients. (g) Wavelength dependence of total attenuation coefficients of mucosa in trachea. (h) Three-dimensional (3D) image at 1700 nm (Media 1). A 3D image at 800 nm is also shown as a movie in Media 2. Important features inside the sample can be distinguished, such as the epithelium layer (ep), the mucosa layer (m), and cartilage (ca).

Fig. 11
Fig. 11

Total attenuation coefficients of (a) industrially used materials and (b) biomedical samples. The absorption coefficients of water [27] and hemoglobin [28] are shown in blue and red lines with arbitrary unit.

Tables (1)

Tables Icon

Table 1 Comparison of total attenuation coefficients of industrially used materials

Equations (3)

Equations on this page are rendered with MathJax. Learn more.

P(z) P 0 K μ b A(z)exp( 2 μ t z )
10log( P(z) P 0 )20 μ t logez+10exp( K μ b A(z) ).
χ 2 i=1 N ( y i y( x i : a 1 .... a M ) σ i ) 2

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