Abstract

A multilayered-substrate model is proposed for surface plasmon resonance (SPR)-based measurement of the thickness of a water layer sandwiched between a lipid bilayer and an underlying support. To calculate sensitivity, a 473 nm-wavelength excitation source and a silver layer are used for the SPR sensor. It is theoretically shown that the multilayered substrate design achieves sufficient sensitivity for such measurements and that sensitivity is enhanced with a SiO2 layer of appropriate thickness and a buffer solution of high refractive index.

© 2011 OSA

Full Article  |  PDF Article

References

  • View by:
  • |
  • |
  • |

  1. K. Morigaki, T. Baumgart, A. Offenhäusser, and W. Knoll, “Patterning solid-supported lipid bilayer membranes by lithographic polymerization of a diacetylene lipid,” Angew. Chem. Int. Ed. Engl. 40(1), 172–174 (2001).
    [CrossRef] [PubMed]
  2. M. Tanaka and E. Sackmann, “Polymer-supported membranes as models of the cell surface,” Nature 437(7059), 656–663 (2005).
    [CrossRef] [PubMed]
  3. K. Watanabe, M. Ryosuke, G. Terakado, T. Okazaki, K. Morigaki, and H. Kano, “High resolution imaging of patterned model biological membranes by localized surface plasmon microscopy,” Appl. Opt. 49(5), 887–891 (2010).
    [CrossRef] [PubMed]
  4. W. C. Lin, C. D. Blanchette, T. V. Ratto, and M. L. Longo, “Lipid asymmetry in DLPC/DSPC-supported lipid bilayers: a combined AFM and fluorescence microscopy study,” Biophys. J. 90(1), 228–237 (2006).
    [CrossRef] [PubMed]
  5. E. Sackmann, “Supported membranes: scientific and practical applications,” Science 271(5245), 43–48 (1996).
    [CrossRef] [PubMed]
  6. B. W. Koenig, H. H. Strey, and K. Gawrisch, “Membrane lateral compressibility determined by NMR and x-ray diffraction: effect of acyl chain polyunsaturation,” Biophys. J. 73(4), 1954–1966 (1997).
    [CrossRef] [PubMed]
  7. B. Rothenhäusler, C. Duschl, and W. Knoll, “Plasmon surface polariton fields for the characterization of thin films,” Thin Solid Films 159(1-2), 323–330 (1988).
    [CrossRef]
  8. W. Hickel and W. Knoll, “Surface plasmon microscopy of lipid layers,” Thin Solid Films 187(2), 349–356 (1990).
    [CrossRef]
  9. E. Kretschmann and H. Raether, “Radiative decay of nonradiative surface plasmons excited by light,” Z. Naturforsch. Tiel A 23A, 2135–2136 (1968).
  10. C. Nylander, B. Liedberg, and T. Lind, “Gas detection by means of surface plasmon resonance,” Sens. Actuators 3, 79–88 (1982).
    [CrossRef]
  11. B. Liedberg, C. Nylander, and I. Lunström, “Surface plasmon resonance for gas detection and biosensing,” Sens. Actuators 4, 299–304 (1983).
    [CrossRef]
  12. L. S. Jung, C. T. Campbell, T. M. Chinowsky, M. N. Mar, and S. S. Yee, “Quantitative interpretation of the response of surface plasmon resonance sensors to adsorbed films,” Langmuir 14(19), 5636–5648 (1998).
    [CrossRef]
  13. J. S. Shumaker-Parry and C. T. Campbell, “Quantitative methods for spatially resolved adsorption/desorption measurements in real time by surface plasmon resonance microscopy,” Anal. Chem. 76(4), 907–917 (2004).
    [CrossRef] [PubMed]
  14. H. Raether, Surface Plasmons on Smooth and Rough Surfaces and on Gratings (Springer, 1988).
  15. K. Tawa and K. Morigaki, “Substrate-supported phospholipid membranes studied by surface plasmon resonance and surface plasmon fluorescence spectroscopy,” Biophys. J. 89(4), 2750–2758 (2005).
    [CrossRef] [PubMed]
  16. J. F. Nagle and S. Tristram-Nagle, “Structure of lipid bilayers,” Biochim. Biophys. Acta 1469(3), 159–195 (2000).
    [PubMed]
  17. C. Huang and T. E. Thompson, “Properties of lipid bilayer membranes separating two aqueous phases: determination of membrane thickness,” J. Mol. Biol. 13(1), 183–193 (1965).
    [CrossRef] [PubMed]

2010 (1)

2006 (1)

W. C. Lin, C. D. Blanchette, T. V. Ratto, and M. L. Longo, “Lipid asymmetry in DLPC/DSPC-supported lipid bilayers: a combined AFM and fluorescence microscopy study,” Biophys. J. 90(1), 228–237 (2006).
[CrossRef] [PubMed]

2005 (2)

M. Tanaka and E. Sackmann, “Polymer-supported membranes as models of the cell surface,” Nature 437(7059), 656–663 (2005).
[CrossRef] [PubMed]

K. Tawa and K. Morigaki, “Substrate-supported phospholipid membranes studied by surface plasmon resonance and surface plasmon fluorescence spectroscopy,” Biophys. J. 89(4), 2750–2758 (2005).
[CrossRef] [PubMed]

2004 (1)

J. S. Shumaker-Parry and C. T. Campbell, “Quantitative methods for spatially resolved adsorption/desorption measurements in real time by surface plasmon resonance microscopy,” Anal. Chem. 76(4), 907–917 (2004).
[CrossRef] [PubMed]

2001 (1)

K. Morigaki, T. Baumgart, A. Offenhäusser, and W. Knoll, “Patterning solid-supported lipid bilayer membranes by lithographic polymerization of a diacetylene lipid,” Angew. Chem. Int. Ed. Engl. 40(1), 172–174 (2001).
[CrossRef] [PubMed]

2000 (1)

J. F. Nagle and S. Tristram-Nagle, “Structure of lipid bilayers,” Biochim. Biophys. Acta 1469(3), 159–195 (2000).
[PubMed]

1998 (1)

L. S. Jung, C. T. Campbell, T. M. Chinowsky, M. N. Mar, and S. S. Yee, “Quantitative interpretation of the response of surface plasmon resonance sensors to adsorbed films,” Langmuir 14(19), 5636–5648 (1998).
[CrossRef]

1997 (1)

B. W. Koenig, H. H. Strey, and K. Gawrisch, “Membrane lateral compressibility determined by NMR and x-ray diffraction: effect of acyl chain polyunsaturation,” Biophys. J. 73(4), 1954–1966 (1997).
[CrossRef] [PubMed]

1996 (1)

E. Sackmann, “Supported membranes: scientific and practical applications,” Science 271(5245), 43–48 (1996).
[CrossRef] [PubMed]

1990 (1)

W. Hickel and W. Knoll, “Surface plasmon microscopy of lipid layers,” Thin Solid Films 187(2), 349–356 (1990).
[CrossRef]

1988 (1)

B. Rothenhäusler, C. Duschl, and W. Knoll, “Plasmon surface polariton fields for the characterization of thin films,” Thin Solid Films 159(1-2), 323–330 (1988).
[CrossRef]

1983 (1)

B. Liedberg, C. Nylander, and I. Lunström, “Surface plasmon resonance for gas detection and biosensing,” Sens. Actuators 4, 299–304 (1983).
[CrossRef]

1982 (1)

C. Nylander, B. Liedberg, and T. Lind, “Gas detection by means of surface plasmon resonance,” Sens. Actuators 3, 79–88 (1982).
[CrossRef]

1968 (1)

E. Kretschmann and H. Raether, “Radiative decay of nonradiative surface plasmons excited by light,” Z. Naturforsch. Tiel A 23A, 2135–2136 (1968).

1965 (1)

C. Huang and T. E. Thompson, “Properties of lipid bilayer membranes separating two aqueous phases: determination of membrane thickness,” J. Mol. Biol. 13(1), 183–193 (1965).
[CrossRef] [PubMed]

Baumgart, T.

K. Morigaki, T. Baumgart, A. Offenhäusser, and W. Knoll, “Patterning solid-supported lipid bilayer membranes by lithographic polymerization of a diacetylene lipid,” Angew. Chem. Int. Ed. Engl. 40(1), 172–174 (2001).
[CrossRef] [PubMed]

Blanchette, C. D.

W. C. Lin, C. D. Blanchette, T. V. Ratto, and M. L. Longo, “Lipid asymmetry in DLPC/DSPC-supported lipid bilayers: a combined AFM and fluorescence microscopy study,” Biophys. J. 90(1), 228–237 (2006).
[CrossRef] [PubMed]

Campbell, C. T.

J. S. Shumaker-Parry and C. T. Campbell, “Quantitative methods for spatially resolved adsorption/desorption measurements in real time by surface plasmon resonance microscopy,” Anal. Chem. 76(4), 907–917 (2004).
[CrossRef] [PubMed]

L. S. Jung, C. T. Campbell, T. M. Chinowsky, M. N. Mar, and S. S. Yee, “Quantitative interpretation of the response of surface plasmon resonance sensors to adsorbed films,” Langmuir 14(19), 5636–5648 (1998).
[CrossRef]

Chinowsky, T. M.

L. S. Jung, C. T. Campbell, T. M. Chinowsky, M. N. Mar, and S. S. Yee, “Quantitative interpretation of the response of surface plasmon resonance sensors to adsorbed films,” Langmuir 14(19), 5636–5648 (1998).
[CrossRef]

Duschl, C.

B. Rothenhäusler, C. Duschl, and W. Knoll, “Plasmon surface polariton fields for the characterization of thin films,” Thin Solid Films 159(1-2), 323–330 (1988).
[CrossRef]

Gawrisch, K.

B. W. Koenig, H. H. Strey, and K. Gawrisch, “Membrane lateral compressibility determined by NMR and x-ray diffraction: effect of acyl chain polyunsaturation,” Biophys. J. 73(4), 1954–1966 (1997).
[CrossRef] [PubMed]

Hickel, W.

W. Hickel and W. Knoll, “Surface plasmon microscopy of lipid layers,” Thin Solid Films 187(2), 349–356 (1990).
[CrossRef]

Huang, C.

C. Huang and T. E. Thompson, “Properties of lipid bilayer membranes separating two aqueous phases: determination of membrane thickness,” J. Mol. Biol. 13(1), 183–193 (1965).
[CrossRef] [PubMed]

Jung, L. S.

L. S. Jung, C. T. Campbell, T. M. Chinowsky, M. N. Mar, and S. S. Yee, “Quantitative interpretation of the response of surface plasmon resonance sensors to adsorbed films,” Langmuir 14(19), 5636–5648 (1998).
[CrossRef]

Kano, H.

Knoll, W.

K. Morigaki, T. Baumgart, A. Offenhäusser, and W. Knoll, “Patterning solid-supported lipid bilayer membranes by lithographic polymerization of a diacetylene lipid,” Angew. Chem. Int. Ed. Engl. 40(1), 172–174 (2001).
[CrossRef] [PubMed]

W. Hickel and W. Knoll, “Surface plasmon microscopy of lipid layers,” Thin Solid Films 187(2), 349–356 (1990).
[CrossRef]

B. Rothenhäusler, C. Duschl, and W. Knoll, “Plasmon surface polariton fields for the characterization of thin films,” Thin Solid Films 159(1-2), 323–330 (1988).
[CrossRef]

Koenig, B. W.

B. W. Koenig, H. H. Strey, and K. Gawrisch, “Membrane lateral compressibility determined by NMR and x-ray diffraction: effect of acyl chain polyunsaturation,” Biophys. J. 73(4), 1954–1966 (1997).
[CrossRef] [PubMed]

Kretschmann, E.

E. Kretschmann and H. Raether, “Radiative decay of nonradiative surface plasmons excited by light,” Z. Naturforsch. Tiel A 23A, 2135–2136 (1968).

Liedberg, B.

B. Liedberg, C. Nylander, and I. Lunström, “Surface plasmon resonance for gas detection and biosensing,” Sens. Actuators 4, 299–304 (1983).
[CrossRef]

C. Nylander, B. Liedberg, and T. Lind, “Gas detection by means of surface plasmon resonance,” Sens. Actuators 3, 79–88 (1982).
[CrossRef]

Lin, W. C.

W. C. Lin, C. D. Blanchette, T. V. Ratto, and M. L. Longo, “Lipid asymmetry in DLPC/DSPC-supported lipid bilayers: a combined AFM and fluorescence microscopy study,” Biophys. J. 90(1), 228–237 (2006).
[CrossRef] [PubMed]

Lind, T.

C. Nylander, B. Liedberg, and T. Lind, “Gas detection by means of surface plasmon resonance,” Sens. Actuators 3, 79–88 (1982).
[CrossRef]

Longo, M. L.

W. C. Lin, C. D. Blanchette, T. V. Ratto, and M. L. Longo, “Lipid asymmetry in DLPC/DSPC-supported lipid bilayers: a combined AFM and fluorescence microscopy study,” Biophys. J. 90(1), 228–237 (2006).
[CrossRef] [PubMed]

Lunström, I.

B. Liedberg, C. Nylander, and I. Lunström, “Surface plasmon resonance for gas detection and biosensing,” Sens. Actuators 4, 299–304 (1983).
[CrossRef]

Mar, M. N.

L. S. Jung, C. T. Campbell, T. M. Chinowsky, M. N. Mar, and S. S. Yee, “Quantitative interpretation of the response of surface plasmon resonance sensors to adsorbed films,” Langmuir 14(19), 5636–5648 (1998).
[CrossRef]

Morigaki, K.

K. Watanabe, M. Ryosuke, G. Terakado, T. Okazaki, K. Morigaki, and H. Kano, “High resolution imaging of patterned model biological membranes by localized surface plasmon microscopy,” Appl. Opt. 49(5), 887–891 (2010).
[CrossRef] [PubMed]

K. Tawa and K. Morigaki, “Substrate-supported phospholipid membranes studied by surface plasmon resonance and surface plasmon fluorescence spectroscopy,” Biophys. J. 89(4), 2750–2758 (2005).
[CrossRef] [PubMed]

K. Morigaki, T. Baumgart, A. Offenhäusser, and W. Knoll, “Patterning solid-supported lipid bilayer membranes by lithographic polymerization of a diacetylene lipid,” Angew. Chem. Int. Ed. Engl. 40(1), 172–174 (2001).
[CrossRef] [PubMed]

Nagle, J. F.

J. F. Nagle and S. Tristram-Nagle, “Structure of lipid bilayers,” Biochim. Biophys. Acta 1469(3), 159–195 (2000).
[PubMed]

Nylander, C.

B. Liedberg, C. Nylander, and I. Lunström, “Surface plasmon resonance for gas detection and biosensing,” Sens. Actuators 4, 299–304 (1983).
[CrossRef]

C. Nylander, B. Liedberg, and T. Lind, “Gas detection by means of surface plasmon resonance,” Sens. Actuators 3, 79–88 (1982).
[CrossRef]

Offenhäusser, A.

K. Morigaki, T. Baumgart, A. Offenhäusser, and W. Knoll, “Patterning solid-supported lipid bilayer membranes by lithographic polymerization of a diacetylene lipid,” Angew. Chem. Int. Ed. Engl. 40(1), 172–174 (2001).
[CrossRef] [PubMed]

Okazaki, T.

Raether, H.

E. Kretschmann and H. Raether, “Radiative decay of nonradiative surface plasmons excited by light,” Z. Naturforsch. Tiel A 23A, 2135–2136 (1968).

Ratto, T. V.

W. C. Lin, C. D. Blanchette, T. V. Ratto, and M. L. Longo, “Lipid asymmetry in DLPC/DSPC-supported lipid bilayers: a combined AFM and fluorescence microscopy study,” Biophys. J. 90(1), 228–237 (2006).
[CrossRef] [PubMed]

Rothenhäusler, B.

B. Rothenhäusler, C. Duschl, and W. Knoll, “Plasmon surface polariton fields for the characterization of thin films,” Thin Solid Films 159(1-2), 323–330 (1988).
[CrossRef]

Ryosuke, M.

Sackmann, E.

M. Tanaka and E. Sackmann, “Polymer-supported membranes as models of the cell surface,” Nature 437(7059), 656–663 (2005).
[CrossRef] [PubMed]

E. Sackmann, “Supported membranes: scientific and practical applications,” Science 271(5245), 43–48 (1996).
[CrossRef] [PubMed]

Shumaker-Parry, J. S.

J. S. Shumaker-Parry and C. T. Campbell, “Quantitative methods for spatially resolved adsorption/desorption measurements in real time by surface plasmon resonance microscopy,” Anal. Chem. 76(4), 907–917 (2004).
[CrossRef] [PubMed]

Strey, H. H.

B. W. Koenig, H. H. Strey, and K. Gawrisch, “Membrane lateral compressibility determined by NMR and x-ray diffraction: effect of acyl chain polyunsaturation,” Biophys. J. 73(4), 1954–1966 (1997).
[CrossRef] [PubMed]

Tanaka, M.

M. Tanaka and E. Sackmann, “Polymer-supported membranes as models of the cell surface,” Nature 437(7059), 656–663 (2005).
[CrossRef] [PubMed]

Tawa, K.

K. Tawa and K. Morigaki, “Substrate-supported phospholipid membranes studied by surface plasmon resonance and surface plasmon fluorescence spectroscopy,” Biophys. J. 89(4), 2750–2758 (2005).
[CrossRef] [PubMed]

Terakado, G.

Thompson, T. E.

C. Huang and T. E. Thompson, “Properties of lipid bilayer membranes separating two aqueous phases: determination of membrane thickness,” J. Mol. Biol. 13(1), 183–193 (1965).
[CrossRef] [PubMed]

Tristram-Nagle, S.

J. F. Nagle and S. Tristram-Nagle, “Structure of lipid bilayers,” Biochim. Biophys. Acta 1469(3), 159–195 (2000).
[PubMed]

Watanabe, K.

Yee, S. S.

L. S. Jung, C. T. Campbell, T. M. Chinowsky, M. N. Mar, and S. S. Yee, “Quantitative interpretation of the response of surface plasmon resonance sensors to adsorbed films,” Langmuir 14(19), 5636–5648 (1998).
[CrossRef]

Anal. Chem. (1)

J. S. Shumaker-Parry and C. T. Campbell, “Quantitative methods for spatially resolved adsorption/desorption measurements in real time by surface plasmon resonance microscopy,” Anal. Chem. 76(4), 907–917 (2004).
[CrossRef] [PubMed]

Angew. Chem. Int. Ed. Engl. (1)

K. Morigaki, T. Baumgart, A. Offenhäusser, and W. Knoll, “Patterning solid-supported lipid bilayer membranes by lithographic polymerization of a diacetylene lipid,” Angew. Chem. Int. Ed. Engl. 40(1), 172–174 (2001).
[CrossRef] [PubMed]

Appl. Opt. (1)

Biochim. Biophys. Acta (1)

J. F. Nagle and S. Tristram-Nagle, “Structure of lipid bilayers,” Biochim. Biophys. Acta 1469(3), 159–195 (2000).
[PubMed]

Biophys. J. (3)

K. Tawa and K. Morigaki, “Substrate-supported phospholipid membranes studied by surface plasmon resonance and surface plasmon fluorescence spectroscopy,” Biophys. J. 89(4), 2750–2758 (2005).
[CrossRef] [PubMed]

W. C. Lin, C. D. Blanchette, T. V. Ratto, and M. L. Longo, “Lipid asymmetry in DLPC/DSPC-supported lipid bilayers: a combined AFM and fluorescence microscopy study,” Biophys. J. 90(1), 228–237 (2006).
[CrossRef] [PubMed]

B. W. Koenig, H. H. Strey, and K. Gawrisch, “Membrane lateral compressibility determined by NMR and x-ray diffraction: effect of acyl chain polyunsaturation,” Biophys. J. 73(4), 1954–1966 (1997).
[CrossRef] [PubMed]

J. Mol. Biol. (1)

C. Huang and T. E. Thompson, “Properties of lipid bilayer membranes separating two aqueous phases: determination of membrane thickness,” J. Mol. Biol. 13(1), 183–193 (1965).
[CrossRef] [PubMed]

Langmuir (1)

L. S. Jung, C. T. Campbell, T. M. Chinowsky, M. N. Mar, and S. S. Yee, “Quantitative interpretation of the response of surface plasmon resonance sensors to adsorbed films,” Langmuir 14(19), 5636–5648 (1998).
[CrossRef]

Nature (1)

M. Tanaka and E. Sackmann, “Polymer-supported membranes as models of the cell surface,” Nature 437(7059), 656–663 (2005).
[CrossRef] [PubMed]

Science (1)

E. Sackmann, “Supported membranes: scientific and practical applications,” Science 271(5245), 43–48 (1996).
[CrossRef] [PubMed]

Sens. Actuators (2)

C. Nylander, B. Liedberg, and T. Lind, “Gas detection by means of surface plasmon resonance,” Sens. Actuators 3, 79–88 (1982).
[CrossRef]

B. Liedberg, C. Nylander, and I. Lunström, “Surface plasmon resonance for gas detection and biosensing,” Sens. Actuators 4, 299–304 (1983).
[CrossRef]

Thin Solid Films (2)

B. Rothenhäusler, C. Duschl, and W. Knoll, “Plasmon surface polariton fields for the characterization of thin films,” Thin Solid Films 159(1-2), 323–330 (1988).
[CrossRef]

W. Hickel and W. Knoll, “Surface plasmon microscopy of lipid layers,” Thin Solid Films 187(2), 349–356 (1990).
[CrossRef]

Z. Naturforsch. Tiel A (1)

E. Kretschmann and H. Raether, “Radiative decay of nonradiative surface plasmons excited by light,” Z. Naturforsch. Tiel A 23A, 2135–2136 (1968).

Other (1)

H. Raether, Surface Plasmons on Smooth and Rough Surfaces and on Gratings (Springer, 1988).

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (5)

Fig. 1
Fig. 1

(a) Configuration for excitation of surface plasmons. (b) Reflected light intensity as a function of incident angle θ. Curves A and B represent plots for dielectric media with refractive indices of 1.3300 and 1.3356, respectively.

Fig. 2
Fig. 2

Calculation model to determine the sensitivity of measurement of water layer thickness.

Fig. 3
Fig. 3

Plot of n eff/nm as a function of SiO2 thickness.

Fig. 4
Fig. 4

Plots of n eff/nm as a function of n1.

Fig. 5
Fig. 5

Calculated plots of n eff/nm as a function of SiO2 thickness for buffer solutions of various refractive indices increased in steps of 1.0 × 10−3.

Equations (1)

Equations on this page are rendered with MathJax. Learn more.

sin θ sp Real ( 1 n g ( n m 2 n eff 2 n m 2 + n eff 2 ) 1 / 2 ) ,

Metrics