Abstract

In this paper, we monitor the in vitro tissue clearing process of mouse dorsal skin immersed into two types of agents using Mueller matrix microscope. By Mueller matrix polar decomposition, we can see that the major difference between polarization changes due to two kinds of agents is the opposite trend of phase retardance with clearing. For the insight of the connection between different agents with the microstructural and optical changes of cleared tissues, we establish various models to mimic the dynamic process of microphysical features of tissues with clearing time. The mechanisms considered include refractive index matching, collagen shrinkage, more orderly fibers and birefringence variation. We compare the experimental results with simulations based on a single mechanism model and a combined model, respectively, which confirms that an individual possible mechanism cannot explain the polarization phenomena due to clearing. Also by simulations of various clearing models involving two possible mechanisms, we can speculate that formamide and saturated sucrose as agents have respective impacts on tissue features and then cause different polarization changes with clearing. Specifically, collagen shrinkage plus birefringence reduction can better explain the tissue cleared by formamide, and refractive index match plus increased birefringence model is likely to be a proper description of tissue cleared by sucrose. Both simulations and experiments also validate the potential of Mueller matrix microscope as a good tool to understand the interaction between clearing agents and tissues.

© 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

Full Article  |  PDF Article
OSA Recommended Articles
Mueller matrix polarimetry for characterizing microstructural variation of nude mouse skin during tissue optical clearing

Dongsheng Chen, Nan Zeng, Qiaolin Xie, Honghui He, Valery V. Tuchin, and Hui Ma
Biomed. Opt. Express 8(8) 3559-3570 (2017)

Characterizing microstructures of cancerous tissues using multispectral transformed Mueller matrix polarization parameters

Chao He, Honghui He, Jintao Chang, Yang Dong, Shaoxiong Liu, Nan Zeng, Yonghong He, and Hui Ma
Biomed. Opt. Express 6(8) 2934-2945 (2015)

A study on forward scattering Mueller matrix decomposition in anisotropic medium

Yihong Guo, Nan Zeng, Honghui He, Tianliang Yun, E Du, Ran Liao, Yonghong He, and Hui Ma
Opt. Express 21(15) 18361-18370 (2013)

References

  • View by:
  • |
  • |
  • |

  1. D. S. Richardson and J. W. Lichtman, “Clarifying tissue clearing,” Cell 162(2), 246–257 (2015).
    [Crossref] [PubMed]
  2. V. V. Tuchin, I. L. Maksimova, D. A. Zimnyakov, I. L. Kon, A. H. Mavlyutov, and A. A. Mishin, “Light propagation in tissues with controlled optical properties,” J. Biomed. Opt. 2(4), 401–417 (1997).
    [Crossref] [PubMed]
  3. M. T. Ke, Y. Nakai, S. Fujimoto, R. Takayama, S. Yoshida, T. S. Kitajima, M. Sato, and T. Imai, “Super-resolution mapping of neuronal circuitry with an index-optimized clearing agent,” Cell Reports 14(11), 2718–2732 (2016).
    [Crossref] [PubMed]
  4. W. Feng, R. Shi, N. Ma, D. K. Tuchina, V. V. Tuchin, and D. Zhu, “Skin optical clearing potential of disaccharides,” J. Biomed. Opt. 21(8), 081207 (2016).
    [Crossref] [PubMed]
  5. L. Silvestri, I. Costantini, L. Sacconi, and F. S. Pavone, “Clearing of fixed tissue: a review from a microscopist’s perspective,” J. Biomed. Opt. 21(8), 081205 (2016).
    [Crossref] [PubMed]
  6. K. Tainaka, A. Kuno, S. I. Kubota, T. Murakami, and H. R. Ueda, “Chemical principles in tissue clearing and staining protocols for whole-body cell profiling,” Annu. Rev. Cell Dev. Biol. 32(1), 713–741 (2016).
    [Crossref] [PubMed]
  7. K. H. R. Jensen and R. W. Berg, “Advances and perspectives in tissue clearing using CLARITY,” J. Chem. Neuroanat. 86, 19–34 (2017).
    [Crossref] [PubMed]
  8. T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
    [Crossref] [PubMed]
  9. P. Wan, J. Zhu, J. Xu, Y. Li, T. Yu, and D. Zhu, “Evaluation of seven optical clearing methods in mouse brain,” Neurophotonics 5(3), 035007 (2018).
    [Crossref] [PubMed]
  10. D. Zhu, K. V. Larin, Q. Luo, and V. V. Tuchin, “Recent progress in tissue optical clearing,” Laser Photonics Rev. 7(5), 732–757 (2013).
    [Crossref] [PubMed]
  11. K. V. Larin, M. G. Ghosn, A. N. Bashkatov, E. A. Genina, N. A. Trunina, and V. V. Tuchin, “Optical clearing for OCT image enhancement and in-depth monitoring of molecular diffusion,” IEEE J. Sel. Top. Quantum Electron. 18(3), 1244–1259 (2012).
    [Crossref]
  12. R. Shi, M. Chen, V. V. Tuchin, and D. Zhu, “Accessing to arteriovenous blood flow dynamics response using combined laser speckle contrast imaging and skin optical clearing,” Biomed. Opt. Express 6(6), 1977–1989 (2015).
    [Crossref] [PubMed]
  13. Y.-Y. Fu and S.-C. Tang, “Optical clearing facilitates integrated 3D visualization of mouse ileal microstructure and vascular network with high definition,” Microvasc. Res. 80(3), 512–521 (2010).
    [Crossref] [PubMed]
  14. O. Nadiarnykh and P. J. Campagnola, “Retention of polarization signatures in SHG microscopy of scattering tissues through optical clearing,” Opt. Express 17(7), 5794–5806 (2009).
    [Crossref] [PubMed]
  15. O. Nadiarnykh and P. J. Campagnola, SHG and optical clearing, in Second Harmonic Generation Imaging, F. S. Pavone, P. J. Campagnola, eds.(CRC Press, 2014), pp. 169–189.
  16. P. S. Tsai, J. P. Kaufhold, P. Blinder, B. Friedman, P. J. Drew, H. J. Karten, P. D. Lyden, and D. Kleinfeld, “Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels,” J. Neurosci. 29(46), 14553–14570 (2009).
    [Crossref] [PubMed]
  17. I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
    [Crossref] [PubMed]
  18. I. V. Meglinski, D. Y. Churmakov, A. N. Bashkatov, E. A. Genina, and V. V. Tuchin, “The Enhancement of Confocal Images of Tissues at Bulk Optical Immersion,” Laser Phys. 13(1), 65–69 (2004).
  19. T. Kuwajima, A. A. Sitko, P. Bhansali, C. Jurgens, W. Guido, and C. Mason, “ClearT: a detergent- and solvent-free clearing method for neuronal and non-neuronal tissue,” Development 140(6), 1364–1368 (2013).
    [Crossref] [PubMed]
  20. T. Yu, Y. Qi, J. Wang, W. Feng, J. Xu, J. Zhu, Y. Yao, H. Gong, Q. Luo, and D. Zhu, “Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol,” J. Biomed. Opt. 21(8), 081203 (2016).
    [Crossref] [PubMed]
  21. A. Y. Sdobnov, M. E. Darvin, E. A. Genina, A. N. Bashkatov, J. Lademann, and V. V. Tuchin, “Recent progress in tissue optical clearing for spectroscopic application,” Spectrochim. Acta A Mol. Biomol. Spectrosc. 197, 216–229 (2018).
    [Crossref] [PubMed]
  22. W. R. Lee, R. Y. Tsai, C. L. Fang, C. J. Liu, C. H. Hu, and J. Y. Fang, “Microdermabrasion as a novel tool to enhance drug delivery via the skin: an animal study,” Dermatol. Surg. 32(8), 1013–1022 (2006).
    [PubMed]
  23. O. F. Stumpp, A. J. Welch, T. E. Milner, and J. Neev, “Enhancement of transepidermal skin clearing agent delivery using a 980 nm diode laser,” Lasers Surg. Med. 37(4), 278–285 (2005).
    [Crossref] [PubMed]
  24. A. K. Nugroho, G. L. Li, M. Danhof, and J. A. Bouwstra, “Transdermal iontophoresis of rotigotine across human stratum corneum in vitro: influence of pH and NaCl concentration,” Pharm. Res. 21(5), 844–850 (2004).
    [Crossref] [PubMed]
  25. A. Tezel and S. Mitragotri, “Interactions of inertial cavitation bubbles with stratum corneum lipid bilayers during low-frequency sonophoresis,” Biophys. J. 85(6), 3502–3512 (2003).
    [Crossref] [PubMed]
  26. V. V. Tuchin, G. B. Altshuler, A. A. Gavrilova, A. B. Pravdin, D. Tabatadze, J. Childs, and I. V. Yaroslavsky, “Optical clearing of skin using flash lamp-induced enhancement of epidermal permeability,” Lasers Surg. Med. 38(9), 824–836 (2006).
    [Crossref] [PubMed]
  27. S. Carvalho, N. Gueiral, E. Nogueira, R. Henrique, L. Oliveira, and V. V. Tuchin, “Glucose diffusion in colorectal mucosa-a comparative study between normal and cancer tissues,” J. Biomed. Opt. 22(9), 91506 (2017).
    [Crossref] [PubMed]
  28. E. A. Genina, A. N. Bashkatov, and V. V. Tuchin, “Tissue optical immersion clearing,” Expert Rev. Med. Devices 7(6), 825–842 (2010).
    [Crossref] [PubMed]
  29. V. V. Tuchin, “Polarized light interaction with tissues,” J. Biomed. Opt. 21(7), 71114 (2016).
    [Crossref] [PubMed]
  30. B. Kunnen, C. Macdonald, A. Doronin, S. Jacques, M. Eccles, and I. Meglinski, “Application of circularly polarized light for non-invasive diagnosis of cancerous tissues and turbid tissue-like scattering media,” J. Biophotonics 8(4), 317–323 (2015).
    [Crossref] [PubMed]
  31. Y. Wang, H. He, J. Chang, N. Zeng, S. Liu, M. Li, and H. Ma, “Differentiating characteristic microstructural features of cancerous tissues using Mueller matrix microscope,” Micron 79, 8–15 (2015).
    [Crossref] [PubMed]
  32. M. Sun, H. He, N. Zeng, E. Du, Y. Guo, S. Liu, J. Wu, Y. He, and H. Ma, “Characterizing the microstructures of biological tissues using Mueller matrix and transformed polarization parameters,” Biomed. Opt. Express 5(12), 4223–4234 (2014).
    [Crossref] [PubMed]
  33. C. He, H. He, X. Li, J. Chang, Y. Wang, S. Liu, N. Zeng, Y. He, and H. Ma, “Quantitatively differentiating microstructures of tissues by frequency distributions of Mueller matrix images,” J. Biomed. Opt. 20(10), 105009 (2015).
    [Crossref] [PubMed]
  34. S. Alali and A. Vitkin, “Polarized light imaging in biomedicine: emerging Mueller matrix methodologies for bulk tissue assessment,” J. Biomed. Opt. 20(6), 61104 (2015).
    [Crossref] [PubMed]
  35. J. Qi and D. S. Elson, “Mueller polarimetric imaging for surgical and diagnostic applications: a review,” J. Biophotonics 10(8), 950–982 (2017).
    [Crossref] [PubMed]
  36. E. Du, H. He, N. Zeng, Y. Guo, R. Liao, Y. He, and H. Ma, “Two-dimensional backscattering Mueller matrix of sphere-cylinder birefringence media,” J. Biomed. Opt. 17(12), 126016 (2012).
    [Crossref] [PubMed]
  37. D. Chen, N. Zeng, Y. Wang, H. He, V. V. Tuchin, and H. Ma, “Study of optical clearing in polarization measurements by Monte Carlo simulations with anisotropic tissue-mimicking models,” J. Biomed. Opt. 21(8), 081209 (2016).
    [Crossref] [PubMed]
  38. D. Chen, N. Zeng, Q. Xie, H. He, V. V. Tuchin, and H. Ma, “Mueller matrix polarimetry for characterizing microstructural variation of nude mouse skin during tissue optical clearing,” Biomed. Opt. Express 8(8), 3559–3570 (2017).
    [Crossref] [PubMed]
  39. T. Yun, N. Zeng, W. Li, D. Li, X. Jiang, and H. Ma, “Monte Carlo simulation of polarized photon scattering in anisotropic media,” Opt. Express 17(19), 16590–16602 (2009).
    [Crossref] [PubMed]
  40. H. He, N. Zeng, R. Liao, T. Yun, W. Li, Y. He, and H. Ma, “Application of sphere-cylinder scattering model to skeletal muscle,” Opt. Express 18(14), 15104–15112 (2010).
    [Crossref] [PubMed]
  41. Y. Dong, H. He, W. Sheng, J. Wu, and H. Ma, “A quantitative and non-contact technique to characterise microstructural variations of skin tissues during photo-damaging process based on Mueller matrix polarimetry,” Sci. Rep. 7(1), 14702 (2017).
    [Crossref] [PubMed]
  42. A. N. Bashkatov, E. A. Genina, and V. V. Tuchin, “Optical properties of skin, subcutaneous and muscle tissue: A review,” J. Innov. Opt. Health Sci. 4(1), 9–38 (2011).
    [Crossref]
  43. A. N. Bashkatov, E. A. Genina, V. I. Kochubey, and V. V. Tuchin, “Optical properties of human skin, subcutaneous and mucous tissues in the wavelength range from 400 to 2000 nm,” J. Phys. D Appl. Phys. 38(15), 2543–2555 (2005).
    [Crossref]
  44. V. V. Tuchin, “Coherent optical techniques for the analysis of tissue structure and dynamics,” J. Biomed. Opt. 4(1), 106–124 (1999).
    [Crossref] [PubMed]

2018 (3)

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

P. Wan, J. Zhu, J. Xu, Y. Li, T. Yu, and D. Zhu, “Evaluation of seven optical clearing methods in mouse brain,” Neurophotonics 5(3), 035007 (2018).
[Crossref] [PubMed]

A. Y. Sdobnov, M. E. Darvin, E. A. Genina, A. N. Bashkatov, J. Lademann, and V. V. Tuchin, “Recent progress in tissue optical clearing for spectroscopic application,” Spectrochim. Acta A Mol. Biomol. Spectrosc. 197, 216–229 (2018).
[Crossref] [PubMed]

2017 (5)

K. H. R. Jensen and R. W. Berg, “Advances and perspectives in tissue clearing using CLARITY,” J. Chem. Neuroanat. 86, 19–34 (2017).
[Crossref] [PubMed]

S. Carvalho, N. Gueiral, E. Nogueira, R. Henrique, L. Oliveira, and V. V. Tuchin, “Glucose diffusion in colorectal mucosa-a comparative study between normal and cancer tissues,” J. Biomed. Opt. 22(9), 91506 (2017).
[Crossref] [PubMed]

J. Qi and D. S. Elson, “Mueller polarimetric imaging for surgical and diagnostic applications: a review,” J. Biophotonics 10(8), 950–982 (2017).
[Crossref] [PubMed]

D. Chen, N. Zeng, Q. Xie, H. He, V. V. Tuchin, and H. Ma, “Mueller matrix polarimetry for characterizing microstructural variation of nude mouse skin during tissue optical clearing,” Biomed. Opt. Express 8(8), 3559–3570 (2017).
[Crossref] [PubMed]

Y. Dong, H. He, W. Sheng, J. Wu, and H. Ma, “A quantitative and non-contact technique to characterise microstructural variations of skin tissues during photo-damaging process based on Mueller matrix polarimetry,” Sci. Rep. 7(1), 14702 (2017).
[Crossref] [PubMed]

2016 (7)

D. Chen, N. Zeng, Y. Wang, H. He, V. V. Tuchin, and H. Ma, “Study of optical clearing in polarization measurements by Monte Carlo simulations with anisotropic tissue-mimicking models,” J. Biomed. Opt. 21(8), 081209 (2016).
[Crossref] [PubMed]

V. V. Tuchin, “Polarized light interaction with tissues,” J. Biomed. Opt. 21(7), 71114 (2016).
[Crossref] [PubMed]

T. Yu, Y. Qi, J. Wang, W. Feng, J. Xu, J. Zhu, Y. Yao, H. Gong, Q. Luo, and D. Zhu, “Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol,” J. Biomed. Opt. 21(8), 081203 (2016).
[Crossref] [PubMed]

M. T. Ke, Y. Nakai, S. Fujimoto, R. Takayama, S. Yoshida, T. S. Kitajima, M. Sato, and T. Imai, “Super-resolution mapping of neuronal circuitry with an index-optimized clearing agent,” Cell Reports 14(11), 2718–2732 (2016).
[Crossref] [PubMed]

W. Feng, R. Shi, N. Ma, D. K. Tuchina, V. V. Tuchin, and D. Zhu, “Skin optical clearing potential of disaccharides,” J. Biomed. Opt. 21(8), 081207 (2016).
[Crossref] [PubMed]

L. Silvestri, I. Costantini, L. Sacconi, and F. S. Pavone, “Clearing of fixed tissue: a review from a microscopist’s perspective,” J. Biomed. Opt. 21(8), 081205 (2016).
[Crossref] [PubMed]

K. Tainaka, A. Kuno, S. I. Kubota, T. Murakami, and H. R. Ueda, “Chemical principles in tissue clearing and staining protocols for whole-body cell profiling,” Annu. Rev. Cell Dev. Biol. 32(1), 713–741 (2016).
[Crossref] [PubMed]

2015 (7)

R. Shi, M. Chen, V. V. Tuchin, and D. Zhu, “Accessing to arteriovenous blood flow dynamics response using combined laser speckle contrast imaging and skin optical clearing,” Biomed. Opt. Express 6(6), 1977–1989 (2015).
[Crossref] [PubMed]

D. S. Richardson and J. W. Lichtman, “Clarifying tissue clearing,” Cell 162(2), 246–257 (2015).
[Crossref] [PubMed]

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

B. Kunnen, C. Macdonald, A. Doronin, S. Jacques, M. Eccles, and I. Meglinski, “Application of circularly polarized light for non-invasive diagnosis of cancerous tissues and turbid tissue-like scattering media,” J. Biophotonics 8(4), 317–323 (2015).
[Crossref] [PubMed]

Y. Wang, H. He, J. Chang, N. Zeng, S. Liu, M. Li, and H. Ma, “Differentiating characteristic microstructural features of cancerous tissues using Mueller matrix microscope,” Micron 79, 8–15 (2015).
[Crossref] [PubMed]

C. He, H. He, X. Li, J. Chang, Y. Wang, S. Liu, N. Zeng, Y. He, and H. Ma, “Quantitatively differentiating microstructures of tissues by frequency distributions of Mueller matrix images,” J. Biomed. Opt. 20(10), 105009 (2015).
[Crossref] [PubMed]

S. Alali and A. Vitkin, “Polarized light imaging in biomedicine: emerging Mueller matrix methodologies for bulk tissue assessment,” J. Biomed. Opt. 20(6), 61104 (2015).
[Crossref] [PubMed]

2014 (1)

2013 (2)

T. Kuwajima, A. A. Sitko, P. Bhansali, C. Jurgens, W. Guido, and C. Mason, “ClearT: a detergent- and solvent-free clearing method for neuronal and non-neuronal tissue,” Development 140(6), 1364–1368 (2013).
[Crossref] [PubMed]

D. Zhu, K. V. Larin, Q. Luo, and V. V. Tuchin, “Recent progress in tissue optical clearing,” Laser Photonics Rev. 7(5), 732–757 (2013).
[Crossref] [PubMed]

2012 (2)

K. V. Larin, M. G. Ghosn, A. N. Bashkatov, E. A. Genina, N. A. Trunina, and V. V. Tuchin, “Optical clearing for OCT image enhancement and in-depth monitoring of molecular diffusion,” IEEE J. Sel. Top. Quantum Electron. 18(3), 1244–1259 (2012).
[Crossref]

E. Du, H. He, N. Zeng, Y. Guo, R. Liao, Y. He, and H. Ma, “Two-dimensional backscattering Mueller matrix of sphere-cylinder birefringence media,” J. Biomed. Opt. 17(12), 126016 (2012).
[Crossref] [PubMed]

2011 (1)

A. N. Bashkatov, E. A. Genina, and V. V. Tuchin, “Optical properties of skin, subcutaneous and muscle tissue: A review,” J. Innov. Opt. Health Sci. 4(1), 9–38 (2011).
[Crossref]

2010 (3)

H. He, N. Zeng, R. Liao, T. Yun, W. Li, Y. He, and H. Ma, “Application of sphere-cylinder scattering model to skeletal muscle,” Opt. Express 18(14), 15104–15112 (2010).
[Crossref] [PubMed]

Y.-Y. Fu and S.-C. Tang, “Optical clearing facilitates integrated 3D visualization of mouse ileal microstructure and vascular network with high definition,” Microvasc. Res. 80(3), 512–521 (2010).
[Crossref] [PubMed]

E. A. Genina, A. N. Bashkatov, and V. V. Tuchin, “Tissue optical immersion clearing,” Expert Rev. Med. Devices 7(6), 825–842 (2010).
[Crossref] [PubMed]

2009 (3)

O. Nadiarnykh and P. J. Campagnola, “Retention of polarization signatures in SHG microscopy of scattering tissues through optical clearing,” Opt. Express 17(7), 5794–5806 (2009).
[Crossref] [PubMed]

P. S. Tsai, J. P. Kaufhold, P. Blinder, B. Friedman, P. J. Drew, H. J. Karten, P. D. Lyden, and D. Kleinfeld, “Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels,” J. Neurosci. 29(46), 14553–14570 (2009).
[Crossref] [PubMed]

T. Yun, N. Zeng, W. Li, D. Li, X. Jiang, and H. Ma, “Monte Carlo simulation of polarized photon scattering in anisotropic media,” Opt. Express 17(19), 16590–16602 (2009).
[Crossref] [PubMed]

2006 (2)

V. V. Tuchin, G. B. Altshuler, A. A. Gavrilova, A. B. Pravdin, D. Tabatadze, J. Childs, and I. V. Yaroslavsky, “Optical clearing of skin using flash lamp-induced enhancement of epidermal permeability,” Lasers Surg. Med. 38(9), 824–836 (2006).
[Crossref] [PubMed]

W. R. Lee, R. Y. Tsai, C. L. Fang, C. J. Liu, C. H. Hu, and J. Y. Fang, “Microdermabrasion as a novel tool to enhance drug delivery via the skin: an animal study,” Dermatol. Surg. 32(8), 1013–1022 (2006).
[PubMed]

2005 (2)

O. F. Stumpp, A. J. Welch, T. E. Milner, and J. Neev, “Enhancement of transepidermal skin clearing agent delivery using a 980 nm diode laser,” Lasers Surg. Med. 37(4), 278–285 (2005).
[Crossref] [PubMed]

A. N. Bashkatov, E. A. Genina, V. I. Kochubey, and V. V. Tuchin, “Optical properties of human skin, subcutaneous and mucous tissues in the wavelength range from 400 to 2000 nm,” J. Phys. D Appl. Phys. 38(15), 2543–2555 (2005).
[Crossref]

2004 (2)

A. K. Nugroho, G. L. Li, M. Danhof, and J. A. Bouwstra, “Transdermal iontophoresis of rotigotine across human stratum corneum in vitro: influence of pH and NaCl concentration,” Pharm. Res. 21(5), 844–850 (2004).
[Crossref] [PubMed]

I. V. Meglinski, D. Y. Churmakov, A. N. Bashkatov, E. A. Genina, and V. V. Tuchin, “The Enhancement of Confocal Images of Tissues at Bulk Optical Immersion,” Laser Phys. 13(1), 65–69 (2004).

2003 (1)

A. Tezel and S. Mitragotri, “Interactions of inertial cavitation bubbles with stratum corneum lipid bilayers during low-frequency sonophoresis,” Biophys. J. 85(6), 3502–3512 (2003).
[Crossref] [PubMed]

1999 (1)

V. V. Tuchin, “Coherent optical techniques for the analysis of tissue structure and dynamics,” J. Biomed. Opt. 4(1), 106–124 (1999).
[Crossref] [PubMed]

1997 (1)

V. V. Tuchin, I. L. Maksimova, D. A. Zimnyakov, I. L. Kon, A. H. Mavlyutov, and A. A. Mishin, “Light propagation in tissues with controlled optical properties,” J. Biomed. Opt. 2(4), 401–417 (1997).
[Crossref] [PubMed]

Alali, S.

S. Alali and A. Vitkin, “Polarized light imaging in biomedicine: emerging Mueller matrix methodologies for bulk tissue assessment,” J. Biomed. Opt. 20(6), 61104 (2015).
[Crossref] [PubMed]

Allegra Mascaro, A. L.

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

Altshuler, G. B.

V. V. Tuchin, G. B. Altshuler, A. A. Gavrilova, A. B. Pravdin, D. Tabatadze, J. Childs, and I. V. Yaroslavsky, “Optical clearing of skin using flash lamp-induced enhancement of epidermal permeability,” Lasers Surg. Med. 38(9), 824–836 (2006).
[Crossref] [PubMed]

Bashkatov, A. N.

A. Y. Sdobnov, M. E. Darvin, E. A. Genina, A. N. Bashkatov, J. Lademann, and V. V. Tuchin, “Recent progress in tissue optical clearing for spectroscopic application,” Spectrochim. Acta A Mol. Biomol. Spectrosc. 197, 216–229 (2018).
[Crossref] [PubMed]

K. V. Larin, M. G. Ghosn, A. N. Bashkatov, E. A. Genina, N. A. Trunina, and V. V. Tuchin, “Optical clearing for OCT image enhancement and in-depth monitoring of molecular diffusion,” IEEE J. Sel. Top. Quantum Electron. 18(3), 1244–1259 (2012).
[Crossref]

A. N. Bashkatov, E. A. Genina, and V. V. Tuchin, “Optical properties of skin, subcutaneous and muscle tissue: A review,” J. Innov. Opt. Health Sci. 4(1), 9–38 (2011).
[Crossref]

E. A. Genina, A. N. Bashkatov, and V. V. Tuchin, “Tissue optical immersion clearing,” Expert Rev. Med. Devices 7(6), 825–842 (2010).
[Crossref] [PubMed]

A. N. Bashkatov, E. A. Genina, V. I. Kochubey, and V. V. Tuchin, “Optical properties of human skin, subcutaneous and mucous tissues in the wavelength range from 400 to 2000 nm,” J. Phys. D Appl. Phys. 38(15), 2543–2555 (2005).
[Crossref]

I. V. Meglinski, D. Y. Churmakov, A. N. Bashkatov, E. A. Genina, and V. V. Tuchin, “The Enhancement of Confocal Images of Tissues at Bulk Optical Immersion,” Laser Phys. 13(1), 65–69 (2004).

Berg, R. W.

K. H. R. Jensen and R. W. Berg, “Advances and perspectives in tissue clearing using CLARITY,” J. Chem. Neuroanat. 86, 19–34 (2017).
[Crossref] [PubMed]

Bhansali, P.

T. Kuwajima, A. A. Sitko, P. Bhansali, C. Jurgens, W. Guido, and C. Mason, “ClearT: a detergent- and solvent-free clearing method for neuronal and non-neuronal tissue,” Development 140(6), 1364–1368 (2013).
[Crossref] [PubMed]

Blinder, P.

P. S. Tsai, J. P. Kaufhold, P. Blinder, B. Friedman, P. J. Drew, H. J. Karten, P. D. Lyden, and D. Kleinfeld, “Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels,” J. Neurosci. 29(46), 14553–14570 (2009).
[Crossref] [PubMed]

Bouwstra, J. A.

A. K. Nugroho, G. L. Li, M. Danhof, and J. A. Bouwstra, “Transdermal iontophoresis of rotigotine across human stratum corneum in vitro: influence of pH and NaCl concentration,” Pharm. Res. 21(5), 844–850 (2004).
[Crossref] [PubMed]

Campagnola, P. J.

Carvalho, S.

S. Carvalho, N. Gueiral, E. Nogueira, R. Henrique, L. Oliveira, and V. V. Tuchin, “Glucose diffusion in colorectal mucosa-a comparative study between normal and cancer tissues,” J. Biomed. Opt. 22(9), 91506 (2017).
[Crossref] [PubMed]

Chang, J.

Y. Wang, H. He, J. Chang, N. Zeng, S. Liu, M. Li, and H. Ma, “Differentiating characteristic microstructural features of cancerous tissues using Mueller matrix microscope,” Micron 79, 8–15 (2015).
[Crossref] [PubMed]

C. He, H. He, X. Li, J. Chang, Y. Wang, S. Liu, N. Zeng, Y. He, and H. Ma, “Quantitatively differentiating microstructures of tissues by frequency distributions of Mueller matrix images,” J. Biomed. Opt. 20(10), 105009 (2015).
[Crossref] [PubMed]

Chen, D.

D. Chen, N. Zeng, Q. Xie, H. He, V. V. Tuchin, and H. Ma, “Mueller matrix polarimetry for characterizing microstructural variation of nude mouse skin during tissue optical clearing,” Biomed. Opt. Express 8(8), 3559–3570 (2017).
[Crossref] [PubMed]

D. Chen, N. Zeng, Y. Wang, H. He, V. V. Tuchin, and H. Ma, “Study of optical clearing in polarization measurements by Monte Carlo simulations with anisotropic tissue-mimicking models,” J. Biomed. Opt. 21(8), 081209 (2016).
[Crossref] [PubMed]

Chen, M.

Cheng, X.

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

Childs, J.

V. V. Tuchin, G. B. Altshuler, A. A. Gavrilova, A. B. Pravdin, D. Tabatadze, J. Childs, and I. V. Yaroslavsky, “Optical clearing of skin using flash lamp-induced enhancement of epidermal permeability,” Lasers Surg. Med. 38(9), 824–836 (2006).
[Crossref] [PubMed]

Churmakov, D. Y.

I. V. Meglinski, D. Y. Churmakov, A. N. Bashkatov, E. A. Genina, and V. V. Tuchin, “The Enhancement of Confocal Images of Tissues at Bulk Optical Immersion,” Laser Phys. 13(1), 65–69 (2004).

Conti, V.

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

Costantini, I.

L. Silvestri, I. Costantini, L. Sacconi, and F. S. Pavone, “Clearing of fixed tissue: a review from a microscopist’s perspective,” J. Biomed. Opt. 21(8), 081205 (2016).
[Crossref] [PubMed]

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

Danhof, M.

A. K. Nugroho, G. L. Li, M. Danhof, and J. A. Bouwstra, “Transdermal iontophoresis of rotigotine across human stratum corneum in vitro: influence of pH and NaCl concentration,” Pharm. Res. 21(5), 844–850 (2004).
[Crossref] [PubMed]

Darvin, M. E.

A. Y. Sdobnov, M. E. Darvin, E. A. Genina, A. N. Bashkatov, J. Lademann, and V. V. Tuchin, “Recent progress in tissue optical clearing for spectroscopic application,” Spectrochim. Acta A Mol. Biomol. Spectrosc. 197, 216–229 (2018).
[Crossref] [PubMed]

Di Giovanna, A. P.

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

Dong, Y.

Y. Dong, H. He, W. Sheng, J. Wu, and H. Ma, “A quantitative and non-contact technique to characterise microstructural variations of skin tissues during photo-damaging process based on Mueller matrix polarimetry,” Sci. Rep. 7(1), 14702 (2017).
[Crossref] [PubMed]

Doronin, A.

B. Kunnen, C. Macdonald, A. Doronin, S. Jacques, M. Eccles, and I. Meglinski, “Application of circularly polarized light for non-invasive diagnosis of cancerous tissues and turbid tissue-like scattering media,” J. Biophotonics 8(4), 317–323 (2015).
[Crossref] [PubMed]

Drew, P. J.

P. S. Tsai, J. P. Kaufhold, P. Blinder, B. Friedman, P. J. Drew, H. J. Karten, P. D. Lyden, and D. Kleinfeld, “Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels,” J. Neurosci. 29(46), 14553–14570 (2009).
[Crossref] [PubMed]

Du, E.

M. Sun, H. He, N. Zeng, E. Du, Y. Guo, S. Liu, J. Wu, Y. He, and H. Ma, “Characterizing the microstructures of biological tissues using Mueller matrix and transformed polarization parameters,” Biomed. Opt. Express 5(12), 4223–4234 (2014).
[Crossref] [PubMed]

E. Du, H. He, N. Zeng, Y. Guo, R. Liao, Y. He, and H. Ma, “Two-dimensional backscattering Mueller matrix of sphere-cylinder birefringence media,” J. Biomed. Opt. 17(12), 126016 (2012).
[Crossref] [PubMed]

Eccles, M.

B. Kunnen, C. Macdonald, A. Doronin, S. Jacques, M. Eccles, and I. Meglinski, “Application of circularly polarized light for non-invasive diagnosis of cancerous tissues and turbid tissue-like scattering media,” J. Biophotonics 8(4), 317–323 (2015).
[Crossref] [PubMed]

Elson, D. S.

J. Qi and D. S. Elson, “Mueller polarimetric imaging for surgical and diagnostic applications: a review,” J. Biophotonics 10(8), 950–982 (2017).
[Crossref] [PubMed]

Fang, C. L.

W. R. Lee, R. Y. Tsai, C. L. Fang, C. J. Liu, C. H. Hu, and J. Y. Fang, “Microdermabrasion as a novel tool to enhance drug delivery via the skin: an animal study,” Dermatol. Surg. 32(8), 1013–1022 (2006).
[PubMed]

Fang, J. Y.

W. R. Lee, R. Y. Tsai, C. L. Fang, C. J. Liu, C. H. Hu, and J. Y. Fang, “Microdermabrasion as a novel tool to enhance drug delivery via the skin: an animal study,” Dermatol. Surg. 32(8), 1013–1022 (2006).
[PubMed]

Feng, W.

T. Yu, Y. Qi, J. Wang, W. Feng, J. Xu, J. Zhu, Y. Yao, H. Gong, Q. Luo, and D. Zhu, “Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol,” J. Biomed. Opt. 21(8), 081203 (2016).
[Crossref] [PubMed]

W. Feng, R. Shi, N. Ma, D. K. Tuchina, V. V. Tuchin, and D. Zhu, “Skin optical clearing potential of disaccharides,” J. Biomed. Opt. 21(8), 081207 (2016).
[Crossref] [PubMed]

Friedman, B.

P. S. Tsai, J. P. Kaufhold, P. Blinder, B. Friedman, P. J. Drew, H. J. Karten, P. D. Lyden, and D. Kleinfeld, “Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels,” J. Neurosci. 29(46), 14553–14570 (2009).
[Crossref] [PubMed]

Fu, Y.-Y.

Y.-Y. Fu and S.-C. Tang, “Optical clearing facilitates integrated 3D visualization of mouse ileal microstructure and vascular network with high definition,” Microvasc. Res. 80(3), 512–521 (2010).
[Crossref] [PubMed]

Fujimoto, S.

M. T. Ke, Y. Nakai, S. Fujimoto, R. Takayama, S. Yoshida, T. S. Kitajima, M. Sato, and T. Imai, “Super-resolution mapping of neuronal circuitry with an index-optimized clearing agent,” Cell Reports 14(11), 2718–2732 (2016).
[Crossref] [PubMed]

Gavrilova, A. A.

V. V. Tuchin, G. B. Altshuler, A. A. Gavrilova, A. B. Pravdin, D. Tabatadze, J. Childs, and I. V. Yaroslavsky, “Optical clearing of skin using flash lamp-induced enhancement of epidermal permeability,” Lasers Surg. Med. 38(9), 824–836 (2006).
[Crossref] [PubMed]

Genina, E. A.

A. Y. Sdobnov, M. E. Darvin, E. A. Genina, A. N. Bashkatov, J. Lademann, and V. V. Tuchin, “Recent progress in tissue optical clearing for spectroscopic application,” Spectrochim. Acta A Mol. Biomol. Spectrosc. 197, 216–229 (2018).
[Crossref] [PubMed]

K. V. Larin, M. G. Ghosn, A. N. Bashkatov, E. A. Genina, N. A. Trunina, and V. V. Tuchin, “Optical clearing for OCT image enhancement and in-depth monitoring of molecular diffusion,” IEEE J. Sel. Top. Quantum Electron. 18(3), 1244–1259 (2012).
[Crossref]

A. N. Bashkatov, E. A. Genina, and V. V. Tuchin, “Optical properties of skin, subcutaneous and muscle tissue: A review,” J. Innov. Opt. Health Sci. 4(1), 9–38 (2011).
[Crossref]

E. A. Genina, A. N. Bashkatov, and V. V. Tuchin, “Tissue optical immersion clearing,” Expert Rev. Med. Devices 7(6), 825–842 (2010).
[Crossref] [PubMed]

A. N. Bashkatov, E. A. Genina, V. I. Kochubey, and V. V. Tuchin, “Optical properties of human skin, subcutaneous and mucous tissues in the wavelength range from 400 to 2000 nm,” J. Phys. D Appl. Phys. 38(15), 2543–2555 (2005).
[Crossref]

I. V. Meglinski, D. Y. Churmakov, A. N. Bashkatov, E. A. Genina, and V. V. Tuchin, “The Enhancement of Confocal Images of Tissues at Bulk Optical Immersion,” Laser Phys. 13(1), 65–69 (2004).

Ghobril, J. P.

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

Ghosn, M. G.

K. V. Larin, M. G. Ghosn, A. N. Bashkatov, E. A. Genina, N. A. Trunina, and V. V. Tuchin, “Optical clearing for OCT image enhancement and in-depth monitoring of molecular diffusion,” IEEE J. Sel. Top. Quantum Electron. 18(3), 1244–1259 (2012).
[Crossref]

Gong, H.

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

T. Yu, Y. Qi, J. Wang, W. Feng, J. Xu, J. Zhu, Y. Yao, H. Gong, Q. Luo, and D. Zhu, “Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol,” J. Biomed. Opt. 21(8), 081203 (2016).
[Crossref] [PubMed]

Gueiral, N.

S. Carvalho, N. Gueiral, E. Nogueira, R. Henrique, L. Oliveira, and V. V. Tuchin, “Glucose diffusion in colorectal mucosa-a comparative study between normal and cancer tissues,” J. Biomed. Opt. 22(9), 91506 (2017).
[Crossref] [PubMed]

Guerrini, R.

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

Guido, W.

T. Kuwajima, A. A. Sitko, P. Bhansali, C. Jurgens, W. Guido, and C. Mason, “ClearT: a detergent- and solvent-free clearing method for neuronal and non-neuronal tissue,” Development 140(6), 1364–1368 (2013).
[Crossref] [PubMed]

Guo, Y.

M. Sun, H. He, N. Zeng, E. Du, Y. Guo, S. Liu, J. Wu, Y. He, and H. Ma, “Characterizing the microstructures of biological tissues using Mueller matrix and transformed polarization parameters,” Biomed. Opt. Express 5(12), 4223–4234 (2014).
[Crossref] [PubMed]

E. Du, H. He, N. Zeng, Y. Guo, R. Liao, Y. He, and H. Ma, “Two-dimensional backscattering Mueller matrix of sphere-cylinder birefringence media,” J. Biomed. Opt. 17(12), 126016 (2012).
[Crossref] [PubMed]

He, C.

C. He, H. He, X. Li, J. Chang, Y. Wang, S. Liu, N. Zeng, Y. He, and H. Ma, “Quantitatively differentiating microstructures of tissues by frequency distributions of Mueller matrix images,” J. Biomed. Opt. 20(10), 105009 (2015).
[Crossref] [PubMed]

He, H.

Y. Dong, H. He, W. Sheng, J. Wu, and H. Ma, “A quantitative and non-contact technique to characterise microstructural variations of skin tissues during photo-damaging process based on Mueller matrix polarimetry,” Sci. Rep. 7(1), 14702 (2017).
[Crossref] [PubMed]

D. Chen, N. Zeng, Q. Xie, H. He, V. V. Tuchin, and H. Ma, “Mueller matrix polarimetry for characterizing microstructural variation of nude mouse skin during tissue optical clearing,” Biomed. Opt. Express 8(8), 3559–3570 (2017).
[Crossref] [PubMed]

D. Chen, N. Zeng, Y. Wang, H. He, V. V. Tuchin, and H. Ma, “Study of optical clearing in polarization measurements by Monte Carlo simulations with anisotropic tissue-mimicking models,” J. Biomed. Opt. 21(8), 081209 (2016).
[Crossref] [PubMed]

C. He, H. He, X. Li, J. Chang, Y. Wang, S. Liu, N. Zeng, Y. He, and H. Ma, “Quantitatively differentiating microstructures of tissues by frequency distributions of Mueller matrix images,” J. Biomed. Opt. 20(10), 105009 (2015).
[Crossref] [PubMed]

Y. Wang, H. He, J. Chang, N. Zeng, S. Liu, M. Li, and H. Ma, “Differentiating characteristic microstructural features of cancerous tissues using Mueller matrix microscope,” Micron 79, 8–15 (2015).
[Crossref] [PubMed]

M. Sun, H. He, N. Zeng, E. Du, Y. Guo, S. Liu, J. Wu, Y. He, and H. Ma, “Characterizing the microstructures of biological tissues using Mueller matrix and transformed polarization parameters,” Biomed. Opt. Express 5(12), 4223–4234 (2014).
[Crossref] [PubMed]

E. Du, H. He, N. Zeng, Y. Guo, R. Liao, Y. He, and H. Ma, “Two-dimensional backscattering Mueller matrix of sphere-cylinder birefringence media,” J. Biomed. Opt. 17(12), 126016 (2012).
[Crossref] [PubMed]

H. He, N. Zeng, R. Liao, T. Yun, W. Li, Y. He, and H. Ma, “Application of sphere-cylinder scattering model to skeletal muscle,” Opt. Express 18(14), 15104–15112 (2010).
[Crossref] [PubMed]

He, Y.

C. He, H. He, X. Li, J. Chang, Y. Wang, S. Liu, N. Zeng, Y. He, and H. Ma, “Quantitatively differentiating microstructures of tissues by frequency distributions of Mueller matrix images,” J. Biomed. Opt. 20(10), 105009 (2015).
[Crossref] [PubMed]

M. Sun, H. He, N. Zeng, E. Du, Y. Guo, S. Liu, J. Wu, Y. He, and H. Ma, “Characterizing the microstructures of biological tissues using Mueller matrix and transformed polarization parameters,” Biomed. Opt. Express 5(12), 4223–4234 (2014).
[Crossref] [PubMed]

E. Du, H. He, N. Zeng, Y. Guo, R. Liao, Y. He, and H. Ma, “Two-dimensional backscattering Mueller matrix of sphere-cylinder birefringence media,” J. Biomed. Opt. 17(12), 126016 (2012).
[Crossref] [PubMed]

H. He, N. Zeng, R. Liao, T. Yun, W. Li, Y. He, and H. Ma, “Application of sphere-cylinder scattering model to skeletal muscle,” Opt. Express 18(14), 15104–15112 (2010).
[Crossref] [PubMed]

Henrique, R.

S. Carvalho, N. Gueiral, E. Nogueira, R. Henrique, L. Oliveira, and V. V. Tuchin, “Glucose diffusion in colorectal mucosa-a comparative study between normal and cancer tissues,” J. Biomed. Opt. 22(9), 91506 (2017).
[Crossref] [PubMed]

Hu, C. H.

W. R. Lee, R. Y. Tsai, C. L. Fang, C. J. Liu, C. H. Hu, and J. Y. Fang, “Microdermabrasion as a novel tool to enhance drug delivery via the skin: an animal study,” Dermatol. Surg. 32(8), 1013–1022 (2006).
[PubMed]

Iannello, G.

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

Imai, T.

M. T. Ke, Y. Nakai, S. Fujimoto, R. Takayama, S. Yoshida, T. S. Kitajima, M. Sato, and T. Imai, “Super-resolution mapping of neuronal circuitry with an index-optimized clearing agent,” Cell Reports 14(11), 2718–2732 (2016).
[Crossref] [PubMed]

Jacques, S.

B. Kunnen, C. Macdonald, A. Doronin, S. Jacques, M. Eccles, and I. Meglinski, “Application of circularly polarized light for non-invasive diagnosis of cancerous tissues and turbid tissue-like scattering media,” J. Biophotonics 8(4), 317–323 (2015).
[Crossref] [PubMed]

Jensen, K. H. R.

K. H. R. Jensen and R. W. Berg, “Advances and perspectives in tissue clearing using CLARITY,” J. Chem. Neuroanat. 86, 19–34 (2017).
[Crossref] [PubMed]

Jiang, X.

Jin, S.

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

Jurgens, C.

T. Kuwajima, A. A. Sitko, P. Bhansali, C. Jurgens, W. Guido, and C. Mason, “ClearT: a detergent- and solvent-free clearing method for neuronal and non-neuronal tissue,” Development 140(6), 1364–1368 (2013).
[Crossref] [PubMed]

Karten, H. J.

P. S. Tsai, J. P. Kaufhold, P. Blinder, B. Friedman, P. J. Drew, H. J. Karten, P. D. Lyden, and D. Kleinfeld, “Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels,” J. Neurosci. 29(46), 14553–14570 (2009).
[Crossref] [PubMed]

Kaufhold, J. P.

P. S. Tsai, J. P. Kaufhold, P. Blinder, B. Friedman, P. J. Drew, H. J. Karten, P. D. Lyden, and D. Kleinfeld, “Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels,” J. Neurosci. 29(46), 14553–14570 (2009).
[Crossref] [PubMed]

Ke, M. T.

M. T. Ke, Y. Nakai, S. Fujimoto, R. Takayama, S. Yoshida, T. S. Kitajima, M. Sato, and T. Imai, “Super-resolution mapping of neuronal circuitry with an index-optimized clearing agent,” Cell Reports 14(11), 2718–2732 (2016).
[Crossref] [PubMed]

Kitajima, T. S.

M. T. Ke, Y. Nakai, S. Fujimoto, R. Takayama, S. Yoshida, T. S. Kitajima, M. Sato, and T. Imai, “Super-resolution mapping of neuronal circuitry with an index-optimized clearing agent,” Cell Reports 14(11), 2718–2732 (2016).
[Crossref] [PubMed]

Kleinfeld, D.

P. S. Tsai, J. P. Kaufhold, P. Blinder, B. Friedman, P. J. Drew, H. J. Karten, P. D. Lyden, and D. Kleinfeld, “Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels,” J. Neurosci. 29(46), 14553–14570 (2009).
[Crossref] [PubMed]

Kochubey, V. I.

A. N. Bashkatov, E. A. Genina, V. I. Kochubey, and V. V. Tuchin, “Optical properties of human skin, subcutaneous and mucous tissues in the wavelength range from 400 to 2000 nm,” J. Phys. D Appl. Phys. 38(15), 2543–2555 (2005).
[Crossref]

Kon, I. L.

V. V. Tuchin, I. L. Maksimova, D. A. Zimnyakov, I. L. Kon, A. H. Mavlyutov, and A. A. Mishin, “Light propagation in tissues with controlled optical properties,” J. Biomed. Opt. 2(4), 401–417 (1997).
[Crossref] [PubMed]

Kubota, S. I.

K. Tainaka, A. Kuno, S. I. Kubota, T. Murakami, and H. R. Ueda, “Chemical principles in tissue clearing and staining protocols for whole-body cell profiling,” Annu. Rev. Cell Dev. Biol. 32(1), 713–741 (2016).
[Crossref] [PubMed]

Kunnen, B.

B. Kunnen, C. Macdonald, A. Doronin, S. Jacques, M. Eccles, and I. Meglinski, “Application of circularly polarized light for non-invasive diagnosis of cancerous tissues and turbid tissue-like scattering media,” J. Biophotonics 8(4), 317–323 (2015).
[Crossref] [PubMed]

Kuno, A.

K. Tainaka, A. Kuno, S. I. Kubota, T. Murakami, and H. R. Ueda, “Chemical principles in tissue clearing and staining protocols for whole-body cell profiling,” Annu. Rev. Cell Dev. Biol. 32(1), 713–741 (2016).
[Crossref] [PubMed]

Kuwajima, T.

T. Kuwajima, A. A. Sitko, P. Bhansali, C. Jurgens, W. Guido, and C. Mason, “ClearT: a detergent- and solvent-free clearing method for neuronal and non-neuronal tissue,” Development 140(6), 1364–1368 (2013).
[Crossref] [PubMed]

Lademann, J.

A. Y. Sdobnov, M. E. Darvin, E. A. Genina, A. N. Bashkatov, J. Lademann, and V. V. Tuchin, “Recent progress in tissue optical clearing for spectroscopic application,” Spectrochim. Acta A Mol. Biomol. Spectrosc. 197, 216–229 (2018).
[Crossref] [PubMed]

Larin, K. V.

D. Zhu, K. V. Larin, Q. Luo, and V. V. Tuchin, “Recent progress in tissue optical clearing,” Laser Photonics Rev. 7(5), 732–757 (2013).
[Crossref] [PubMed]

K. V. Larin, M. G. Ghosn, A. N. Bashkatov, E. A. Genina, N. A. Trunina, and V. V. Tuchin, “Optical clearing for OCT image enhancement and in-depth monitoring of molecular diffusion,” IEEE J. Sel. Top. Quantum Electron. 18(3), 1244–1259 (2012).
[Crossref]

Lee, W. R.

W. R. Lee, R. Y. Tsai, C. L. Fang, C. J. Liu, C. H. Hu, and J. Y. Fang, “Microdermabrasion as a novel tool to enhance drug delivery via the skin: an animal study,” Dermatol. Surg. 32(8), 1013–1022 (2006).
[PubMed]

Li, D.

Li, G. L.

A. K. Nugroho, G. L. Li, M. Danhof, and J. A. Bouwstra, “Transdermal iontophoresis of rotigotine across human stratum corneum in vitro: influence of pH and NaCl concentration,” Pharm. Res. 21(5), 844–850 (2004).
[Crossref] [PubMed]

Li, M.

Y. Wang, H. He, J. Chang, N. Zeng, S. Liu, M. Li, and H. Ma, “Differentiating characteristic microstructural features of cancerous tissues using Mueller matrix microscope,” Micron 79, 8–15 (2015).
[Crossref] [PubMed]

Li, W.

Li, X.

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

C. He, H. He, X. Li, J. Chang, Y. Wang, S. Liu, N. Zeng, Y. He, and H. Ma, “Quantitatively differentiating microstructures of tissues by frequency distributions of Mueller matrix images,” J. Biomed. Opt. 20(10), 105009 (2015).
[Crossref] [PubMed]

Li, Y.

P. Wan, J. Zhu, J. Xu, Y. Li, T. Yu, and D. Zhu, “Evaluation of seven optical clearing methods in mouse brain,” Neurophotonics 5(3), 035007 (2018).
[Crossref] [PubMed]

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

Liao, R.

E. Du, H. He, N. Zeng, Y. Guo, R. Liao, Y. He, and H. Ma, “Two-dimensional backscattering Mueller matrix of sphere-cylinder birefringence media,” J. Biomed. Opt. 17(12), 126016 (2012).
[Crossref] [PubMed]

H. He, N. Zeng, R. Liao, T. Yun, W. Li, Y. He, and H. Ma, “Application of sphere-cylinder scattering model to skeletal muscle,” Opt. Express 18(14), 15104–15112 (2010).
[Crossref] [PubMed]

Lichtman, J. W.

D. S. Richardson and J. W. Lichtman, “Clarifying tissue clearing,” Cell 162(2), 246–257 (2015).
[Crossref] [PubMed]

Liu, C. J.

W. R. Lee, R. Y. Tsai, C. L. Fang, C. J. Liu, C. H. Hu, and J. Y. Fang, “Microdermabrasion as a novel tool to enhance drug delivery via the skin: an animal study,” Dermatol. Surg. 32(8), 1013–1022 (2006).
[PubMed]

Liu, S.

Y. Wang, H. He, J. Chang, N. Zeng, S. Liu, M. Li, and H. Ma, “Differentiating characteristic microstructural features of cancerous tissues using Mueller matrix microscope,” Micron 79, 8–15 (2015).
[Crossref] [PubMed]

C. He, H. He, X. Li, J. Chang, Y. Wang, S. Liu, N. Zeng, Y. He, and H. Ma, “Quantitatively differentiating microstructures of tissues by frequency distributions of Mueller matrix images,” J. Biomed. Opt. 20(10), 105009 (2015).
[Crossref] [PubMed]

M. Sun, H. He, N. Zeng, E. Du, Y. Guo, S. Liu, J. Wu, Y. He, and H. Ma, “Characterizing the microstructures of biological tissues using Mueller matrix and transformed polarization parameters,” Biomed. Opt. Express 5(12), 4223–4234 (2014).
[Crossref] [PubMed]

Luo, Q.

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

T. Yu, Y. Qi, J. Wang, W. Feng, J. Xu, J. Zhu, Y. Yao, H. Gong, Q. Luo, and D. Zhu, “Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol,” J. Biomed. Opt. 21(8), 081203 (2016).
[Crossref] [PubMed]

D. Zhu, K. V. Larin, Q. Luo, and V. V. Tuchin, “Recent progress in tissue optical clearing,” Laser Photonics Rev. 7(5), 732–757 (2013).
[Crossref] [PubMed]

Lyden, P. D.

P. S. Tsai, J. P. Kaufhold, P. Blinder, B. Friedman, P. J. Drew, H. J. Karten, P. D. Lyden, and D. Kleinfeld, “Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels,” J. Neurosci. 29(46), 14553–14570 (2009).
[Crossref] [PubMed]

Ma, H.

D. Chen, N. Zeng, Q. Xie, H. He, V. V. Tuchin, and H. Ma, “Mueller matrix polarimetry for characterizing microstructural variation of nude mouse skin during tissue optical clearing,” Biomed. Opt. Express 8(8), 3559–3570 (2017).
[Crossref] [PubMed]

Y. Dong, H. He, W. Sheng, J. Wu, and H. Ma, “A quantitative and non-contact technique to characterise microstructural variations of skin tissues during photo-damaging process based on Mueller matrix polarimetry,” Sci. Rep. 7(1), 14702 (2017).
[Crossref] [PubMed]

D. Chen, N. Zeng, Y. Wang, H. He, V. V. Tuchin, and H. Ma, “Study of optical clearing in polarization measurements by Monte Carlo simulations with anisotropic tissue-mimicking models,” J. Biomed. Opt. 21(8), 081209 (2016).
[Crossref] [PubMed]

Y. Wang, H. He, J. Chang, N. Zeng, S. Liu, M. Li, and H. Ma, “Differentiating characteristic microstructural features of cancerous tissues using Mueller matrix microscope,” Micron 79, 8–15 (2015).
[Crossref] [PubMed]

C. He, H. He, X. Li, J. Chang, Y. Wang, S. Liu, N. Zeng, Y. He, and H. Ma, “Quantitatively differentiating microstructures of tissues by frequency distributions of Mueller matrix images,” J. Biomed. Opt. 20(10), 105009 (2015).
[Crossref] [PubMed]

M. Sun, H. He, N. Zeng, E. Du, Y. Guo, S. Liu, J. Wu, Y. He, and H. Ma, “Characterizing the microstructures of biological tissues using Mueller matrix and transformed polarization parameters,” Biomed. Opt. Express 5(12), 4223–4234 (2014).
[Crossref] [PubMed]

E. Du, H. He, N. Zeng, Y. Guo, R. Liao, Y. He, and H. Ma, “Two-dimensional backscattering Mueller matrix of sphere-cylinder birefringence media,” J. Biomed. Opt. 17(12), 126016 (2012).
[Crossref] [PubMed]

H. He, N. Zeng, R. Liao, T. Yun, W. Li, Y. He, and H. Ma, “Application of sphere-cylinder scattering model to skeletal muscle,” Opt. Express 18(14), 15104–15112 (2010).
[Crossref] [PubMed]

T. Yun, N. Zeng, W. Li, D. Li, X. Jiang, and H. Ma, “Monte Carlo simulation of polarized photon scattering in anisotropic media,” Opt. Express 17(19), 16590–16602 (2009).
[Crossref] [PubMed]

Ma, N.

W. Feng, R. Shi, N. Ma, D. K. Tuchina, V. V. Tuchin, and D. Zhu, “Skin optical clearing potential of disaccharides,” J. Biomed. Opt. 21(8), 081207 (2016).
[Crossref] [PubMed]

Ma, Y.

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

Macdonald, C.

B. Kunnen, C. Macdonald, A. Doronin, S. Jacques, M. Eccles, and I. Meglinski, “Application of circularly polarized light for non-invasive diagnosis of cancerous tissues and turbid tissue-like scattering media,” J. Biophotonics 8(4), 317–323 (2015).
[Crossref] [PubMed]

Maksimova, I. L.

V. V. Tuchin, I. L. Maksimova, D. A. Zimnyakov, I. L. Kon, A. H. Mavlyutov, and A. A. Mishin, “Light propagation in tissues with controlled optical properties,” J. Biomed. Opt. 2(4), 401–417 (1997).
[Crossref] [PubMed]

Markram, H.

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

Mason, C.

T. Kuwajima, A. A. Sitko, P. Bhansali, C. Jurgens, W. Guido, and C. Mason, “ClearT: a detergent- and solvent-free clearing method for neuronal and non-neuronal tissue,” Development 140(6), 1364–1368 (2013).
[Crossref] [PubMed]

Mavlyutov, A. H.

V. V. Tuchin, I. L. Maksimova, D. A. Zimnyakov, I. L. Kon, A. H. Mavlyutov, and A. A. Mishin, “Light propagation in tissues with controlled optical properties,” J. Biomed. Opt. 2(4), 401–417 (1997).
[Crossref] [PubMed]

Meglinski, I.

B. Kunnen, C. Macdonald, A. Doronin, S. Jacques, M. Eccles, and I. Meglinski, “Application of circularly polarized light for non-invasive diagnosis of cancerous tissues and turbid tissue-like scattering media,” J. Biophotonics 8(4), 317–323 (2015).
[Crossref] [PubMed]

Meglinski, I. V.

I. V. Meglinski, D. Y. Churmakov, A. N. Bashkatov, E. A. Genina, and V. V. Tuchin, “The Enhancement of Confocal Images of Tissues at Bulk Optical Immersion,” Laser Phys. 13(1), 65–69 (2004).

Milner, T. E.

O. F. Stumpp, A. J. Welch, T. E. Milner, and J. Neev, “Enhancement of transepidermal skin clearing agent delivery using a 980 nm diode laser,” Lasers Surg. Med. 37(4), 278–285 (2005).
[Crossref] [PubMed]

Mishin, A. A.

V. V. Tuchin, I. L. Maksimova, D. A. Zimnyakov, I. L. Kon, A. H. Mavlyutov, and A. A. Mishin, “Light propagation in tissues with controlled optical properties,” J. Biomed. Opt. 2(4), 401–417 (1997).
[Crossref] [PubMed]

Mitragotri, S.

A. Tezel and S. Mitragotri, “Interactions of inertial cavitation bubbles with stratum corneum lipid bilayers during low-frequency sonophoresis,” Biophys. J. 85(6), 3502–3512 (2003).
[Crossref] [PubMed]

Müllenbroich, M. C.

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

Murakami, T.

K. Tainaka, A. Kuno, S. I. Kubota, T. Murakami, and H. R. Ueda, “Chemical principles in tissue clearing and staining protocols for whole-body cell profiling,” Annu. Rev. Cell Dev. Biol. 32(1), 713–741 (2016).
[Crossref] [PubMed]

Nadiarnykh, O.

Nakai, Y.

M. T. Ke, Y. Nakai, S. Fujimoto, R. Takayama, S. Yoshida, T. S. Kitajima, M. Sato, and T. Imai, “Super-resolution mapping of neuronal circuitry with an index-optimized clearing agent,” Cell Reports 14(11), 2718–2732 (2016).
[Crossref] [PubMed]

Neev, J.

O. F. Stumpp, A. J. Welch, T. E. Milner, and J. Neev, “Enhancement of transepidermal skin clearing agent delivery using a 980 nm diode laser,” Lasers Surg. Med. 37(4), 278–285 (2005).
[Crossref] [PubMed]

Nogueira, E.

S. Carvalho, N. Gueiral, E. Nogueira, R. Henrique, L. Oliveira, and V. V. Tuchin, “Glucose diffusion in colorectal mucosa-a comparative study between normal and cancer tissues,” J. Biomed. Opt. 22(9), 91506 (2017).
[Crossref] [PubMed]

Nugroho, A. K.

A. K. Nugroho, G. L. Li, M. Danhof, and J. A. Bouwstra, “Transdermal iontophoresis of rotigotine across human stratum corneum in vitro: influence of pH and NaCl concentration,” Pharm. Res. 21(5), 844–850 (2004).
[Crossref] [PubMed]

Oliveira, L.

S. Carvalho, N. Gueiral, E. Nogueira, R. Henrique, L. Oliveira, and V. V. Tuchin, “Glucose diffusion in colorectal mucosa-a comparative study between normal and cancer tissues,” J. Biomed. Opt. 22(9), 91506 (2017).
[Crossref] [PubMed]

Onofri, L.

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

Pavone, F. S.

L. Silvestri, I. Costantini, L. Sacconi, and F. S. Pavone, “Clearing of fixed tissue: a review from a microscopist’s perspective,” J. Biomed. Opt. 21(8), 081205 (2016).
[Crossref] [PubMed]

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

Pravdin, A. B.

V. V. Tuchin, G. B. Altshuler, A. A. Gavrilova, A. B. Pravdin, D. Tabatadze, J. Childs, and I. V. Yaroslavsky, “Optical clearing of skin using flash lamp-induced enhancement of epidermal permeability,” Lasers Surg. Med. 38(9), 824–836 (2006).
[Crossref] [PubMed]

Qi, J.

J. Qi and D. S. Elson, “Mueller polarimetric imaging for surgical and diagnostic applications: a review,” J. Biophotonics 10(8), 950–982 (2017).
[Crossref] [PubMed]

Qi, Y.

T. Yu, Y. Qi, J. Wang, W. Feng, J. Xu, J. Zhu, Y. Yao, H. Gong, Q. Luo, and D. Zhu, “Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol,” J. Biomed. Opt. 21(8), 081203 (2016).
[Crossref] [PubMed]

Richardson, D. S.

D. S. Richardson and J. W. Lichtman, “Clarifying tissue clearing,” Cell 162(2), 246–257 (2015).
[Crossref] [PubMed]

Sacconi, L.

L. Silvestri, I. Costantini, L. Sacconi, and F. S. Pavone, “Clearing of fixed tissue: a review from a microscopist’s perspective,” J. Biomed. Opt. 21(8), 081205 (2016).
[Crossref] [PubMed]

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

Sato, M.

M. T. Ke, Y. Nakai, S. Fujimoto, R. Takayama, S. Yoshida, T. S. Kitajima, M. Sato, and T. Imai, “Super-resolution mapping of neuronal circuitry with an index-optimized clearing agent,” Cell Reports 14(11), 2718–2732 (2016).
[Crossref] [PubMed]

Sdobnov, A. Y.

A. Y. Sdobnov, M. E. Darvin, E. A. Genina, A. N. Bashkatov, J. Lademann, and V. V. Tuchin, “Recent progress in tissue optical clearing for spectroscopic application,” Spectrochim. Acta A Mol. Biomol. Spectrosc. 197, 216–229 (2018).
[Crossref] [PubMed]

Sheng, W.

Y. Dong, H. He, W. Sheng, J. Wu, and H. Ma, “A quantitative and non-contact technique to characterise microstructural variations of skin tissues during photo-damaging process based on Mueller matrix polarimetry,” Sci. Rep. 7(1), 14702 (2017).
[Crossref] [PubMed]

Shi, R.

Silvestri, L.

L. Silvestri, I. Costantini, L. Sacconi, and F. S. Pavone, “Clearing of fixed tissue: a review from a microscopist’s perspective,” J. Biomed. Opt. 21(8), 081205 (2016).
[Crossref] [PubMed]

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

Sitko, A. A.

T. Kuwajima, A. A. Sitko, P. Bhansali, C. Jurgens, W. Guido, and C. Mason, “ClearT: a detergent- and solvent-free clearing method for neuronal and non-neuronal tissue,” Development 140(6), 1364–1368 (2013).
[Crossref] [PubMed]

Stumpp, O. F.

O. F. Stumpp, A. J. Welch, T. E. Milner, and J. Neev, “Enhancement of transepidermal skin clearing agent delivery using a 980 nm diode laser,” Lasers Surg. Med. 37(4), 278–285 (2005).
[Crossref] [PubMed]

Sun, M.

Sun, Q.

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

Tabatadze, D.

V. V. Tuchin, G. B. Altshuler, A. A. Gavrilova, A. B. Pravdin, D. Tabatadze, J. Childs, and I. V. Yaroslavsky, “Optical clearing of skin using flash lamp-induced enhancement of epidermal permeability,” Lasers Surg. Med. 38(9), 824–836 (2006).
[Crossref] [PubMed]

Tainaka, K.

K. Tainaka, A. Kuno, S. I. Kubota, T. Murakami, and H. R. Ueda, “Chemical principles in tissue clearing and staining protocols for whole-body cell profiling,” Annu. Rev. Cell Dev. Biol. 32(1), 713–741 (2016).
[Crossref] [PubMed]

Takayama, R.

M. T. Ke, Y. Nakai, S. Fujimoto, R. Takayama, S. Yoshida, T. S. Kitajima, M. Sato, and T. Imai, “Super-resolution mapping of neuronal circuitry with an index-optimized clearing agent,” Cell Reports 14(11), 2718–2732 (2016).
[Crossref] [PubMed]

Tang, S.-C.

Y.-Y. Fu and S.-C. Tang, “Optical clearing facilitates integrated 3D visualization of mouse ileal microstructure and vascular network with high definition,” Microvasc. Res. 80(3), 512–521 (2010).
[Crossref] [PubMed]

Tezel, A.

A. Tezel and S. Mitragotri, “Interactions of inertial cavitation bubbles with stratum corneum lipid bilayers during low-frequency sonophoresis,” Biophys. J. 85(6), 3502–3512 (2003).
[Crossref] [PubMed]

Trunina, N. A.

K. V. Larin, M. G. Ghosn, A. N. Bashkatov, E. A. Genina, N. A. Trunina, and V. V. Tuchin, “Optical clearing for OCT image enhancement and in-depth monitoring of molecular diffusion,” IEEE J. Sel. Top. Quantum Electron. 18(3), 1244–1259 (2012).
[Crossref]

Tsai, P. S.

P. S. Tsai, J. P. Kaufhold, P. Blinder, B. Friedman, P. J. Drew, H. J. Karten, P. D. Lyden, and D. Kleinfeld, “Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels,” J. Neurosci. 29(46), 14553–14570 (2009).
[Crossref] [PubMed]

Tsai, R. Y.

W. R. Lee, R. Y. Tsai, C. L. Fang, C. J. Liu, C. H. Hu, and J. Y. Fang, “Microdermabrasion as a novel tool to enhance drug delivery via the skin: an animal study,” Dermatol. Surg. 32(8), 1013–1022 (2006).
[PubMed]

Tuchin, V. V.

A. Y. Sdobnov, M. E. Darvin, E. A. Genina, A. N. Bashkatov, J. Lademann, and V. V. Tuchin, “Recent progress in tissue optical clearing for spectroscopic application,” Spectrochim. Acta A Mol. Biomol. Spectrosc. 197, 216–229 (2018).
[Crossref] [PubMed]

S. Carvalho, N. Gueiral, E. Nogueira, R. Henrique, L. Oliveira, and V. V. Tuchin, “Glucose diffusion in colorectal mucosa-a comparative study between normal and cancer tissues,” J. Biomed. Opt. 22(9), 91506 (2017).
[Crossref] [PubMed]

D. Chen, N. Zeng, Q. Xie, H. He, V. V. Tuchin, and H. Ma, “Mueller matrix polarimetry for characterizing microstructural variation of nude mouse skin during tissue optical clearing,” Biomed. Opt. Express 8(8), 3559–3570 (2017).
[Crossref] [PubMed]

D. Chen, N. Zeng, Y. Wang, H. He, V. V. Tuchin, and H. Ma, “Study of optical clearing in polarization measurements by Monte Carlo simulations with anisotropic tissue-mimicking models,” J. Biomed. Opt. 21(8), 081209 (2016).
[Crossref] [PubMed]

V. V. Tuchin, “Polarized light interaction with tissues,” J. Biomed. Opt. 21(7), 71114 (2016).
[Crossref] [PubMed]

W. Feng, R. Shi, N. Ma, D. K. Tuchina, V. V. Tuchin, and D. Zhu, “Skin optical clearing potential of disaccharides,” J. Biomed. Opt. 21(8), 081207 (2016).
[Crossref] [PubMed]

R. Shi, M. Chen, V. V. Tuchin, and D. Zhu, “Accessing to arteriovenous blood flow dynamics response using combined laser speckle contrast imaging and skin optical clearing,” Biomed. Opt. Express 6(6), 1977–1989 (2015).
[Crossref] [PubMed]

D. Zhu, K. V. Larin, Q. Luo, and V. V. Tuchin, “Recent progress in tissue optical clearing,” Laser Photonics Rev. 7(5), 732–757 (2013).
[Crossref] [PubMed]

K. V. Larin, M. G. Ghosn, A. N. Bashkatov, E. A. Genina, N. A. Trunina, and V. V. Tuchin, “Optical clearing for OCT image enhancement and in-depth monitoring of molecular diffusion,” IEEE J. Sel. Top. Quantum Electron. 18(3), 1244–1259 (2012).
[Crossref]

A. N. Bashkatov, E. A. Genina, and V. V. Tuchin, “Optical properties of skin, subcutaneous and muscle tissue: A review,” J. Innov. Opt. Health Sci. 4(1), 9–38 (2011).
[Crossref]

E. A. Genina, A. N. Bashkatov, and V. V. Tuchin, “Tissue optical immersion clearing,” Expert Rev. Med. Devices 7(6), 825–842 (2010).
[Crossref] [PubMed]

V. V. Tuchin, G. B. Altshuler, A. A. Gavrilova, A. B. Pravdin, D. Tabatadze, J. Childs, and I. V. Yaroslavsky, “Optical clearing of skin using flash lamp-induced enhancement of epidermal permeability,” Lasers Surg. Med. 38(9), 824–836 (2006).
[Crossref] [PubMed]

A. N. Bashkatov, E. A. Genina, V. I. Kochubey, and V. V. Tuchin, “Optical properties of human skin, subcutaneous and mucous tissues in the wavelength range from 400 to 2000 nm,” J. Phys. D Appl. Phys. 38(15), 2543–2555 (2005).
[Crossref]

I. V. Meglinski, D. Y. Churmakov, A. N. Bashkatov, E. A. Genina, and V. V. Tuchin, “The Enhancement of Confocal Images of Tissues at Bulk Optical Immersion,” Laser Phys. 13(1), 65–69 (2004).

V. V. Tuchin, “Coherent optical techniques for the analysis of tissue structure and dynamics,” J. Biomed. Opt. 4(1), 106–124 (1999).
[Crossref] [PubMed]

V. V. Tuchin, I. L. Maksimova, D. A. Zimnyakov, I. L. Kon, A. H. Mavlyutov, and A. A. Mishin, “Light propagation in tissues with controlled optical properties,” J. Biomed. Opt. 2(4), 401–417 (1997).
[Crossref] [PubMed]

Tuchina, D. K.

W. Feng, R. Shi, N. Ma, D. K. Tuchina, V. V. Tuchin, and D. Zhu, “Skin optical clearing potential of disaccharides,” J. Biomed. Opt. 21(8), 081207 (2016).
[Crossref] [PubMed]

Ueda, H. R.

K. Tainaka, A. Kuno, S. I. Kubota, T. Murakami, and H. R. Ueda, “Chemical principles in tissue clearing and staining protocols for whole-body cell profiling,” Annu. Rev. Cell Dev. Biol. 32(1), 713–741 (2016).
[Crossref] [PubMed]

Vanzi, F.

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

Vitkin, A.

S. Alali and A. Vitkin, “Polarized light imaging in biomedicine: emerging Mueller matrix methodologies for bulk tissue assessment,” J. Biomed. Opt. 20(6), 61104 (2015).
[Crossref] [PubMed]

Wan, P.

P. Wan, J. Zhu, J. Xu, Y. Li, T. Yu, and D. Zhu, “Evaluation of seven optical clearing methods in mouse brain,” Neurophotonics 5(3), 035007 (2018).
[Crossref] [PubMed]

Wang, J.

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

T. Yu, Y. Qi, J. Wang, W. Feng, J. Xu, J. Zhu, Y. Yao, H. Gong, Q. Luo, and D. Zhu, “Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol,” J. Biomed. Opt. 21(8), 081203 (2016).
[Crossref] [PubMed]

Wang, Y.

D. Chen, N. Zeng, Y. Wang, H. He, V. V. Tuchin, and H. Ma, “Study of optical clearing in polarization measurements by Monte Carlo simulations with anisotropic tissue-mimicking models,” J. Biomed. Opt. 21(8), 081209 (2016).
[Crossref] [PubMed]

Y. Wang, H. He, J. Chang, N. Zeng, S. Liu, M. Li, and H. Ma, “Differentiating characteristic microstructural features of cancerous tissues using Mueller matrix microscope,” Micron 79, 8–15 (2015).
[Crossref] [PubMed]

C. He, H. He, X. Li, J. Chang, Y. Wang, S. Liu, N. Zeng, Y. He, and H. Ma, “Quantitatively differentiating microstructures of tissues by frequency distributions of Mueller matrix images,” J. Biomed. Opt. 20(10), 105009 (2015).
[Crossref] [PubMed]

Welch, A. J.

O. F. Stumpp, A. J. Welch, T. E. Milner, and J. Neev, “Enhancement of transepidermal skin clearing agent delivery using a 980 nm diode laser,” Lasers Surg. Med. 37(4), 278–285 (2005).
[Crossref] [PubMed]

Wu, J.

Y. Dong, H. He, W. Sheng, J. Wu, and H. Ma, “A quantitative and non-contact technique to characterise microstructural variations of skin tissues during photo-damaging process based on Mueller matrix polarimetry,” Sci. Rep. 7(1), 14702 (2017).
[Crossref] [PubMed]

M. Sun, H. He, N. Zeng, E. Du, Y. Guo, S. Liu, J. Wu, Y. He, and H. Ma, “Characterizing the microstructures of biological tissues using Mueller matrix and transformed polarization parameters,” Biomed. Opt. Express 5(12), 4223–4234 (2014).
[Crossref] [PubMed]

Xie, Q.

Xu, F.

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

Xu, J.

P. Wan, J. Zhu, J. Xu, Y. Li, T. Yu, and D. Zhu, “Evaluation of seven optical clearing methods in mouse brain,” Neurophotonics 5(3), 035007 (2018).
[Crossref] [PubMed]

T. Yu, Y. Qi, J. Wang, W. Feng, J. Xu, J. Zhu, Y. Yao, H. Gong, Q. Luo, and D. Zhu, “Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol,” J. Biomed. Opt. 21(8), 081203 (2016).
[Crossref] [PubMed]

Yao, Y.

T. Yu, Y. Qi, J. Wang, W. Feng, J. Xu, J. Zhu, Y. Yao, H. Gong, Q. Luo, and D. Zhu, “Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol,” J. Biomed. Opt. 21(8), 081203 (2016).
[Crossref] [PubMed]

Yaroslavsky, I. V.

V. V. Tuchin, G. B. Altshuler, A. A. Gavrilova, A. B. Pravdin, D. Tabatadze, J. Childs, and I. V. Yaroslavsky, “Optical clearing of skin using flash lamp-induced enhancement of epidermal permeability,” Lasers Surg. Med. 38(9), 824–836 (2006).
[Crossref] [PubMed]

Yoshida, S.

M. T. Ke, Y. Nakai, S. Fujimoto, R. Takayama, S. Yoshida, T. S. Kitajima, M. Sato, and T. Imai, “Super-resolution mapping of neuronal circuitry with an index-optimized clearing agent,” Cell Reports 14(11), 2718–2732 (2016).
[Crossref] [PubMed]

Yu, T.

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

P. Wan, J. Zhu, J. Xu, Y. Li, T. Yu, and D. Zhu, “Evaluation of seven optical clearing methods in mouse brain,” Neurophotonics 5(3), 035007 (2018).
[Crossref] [PubMed]

T. Yu, Y. Qi, J. Wang, W. Feng, J. Xu, J. Zhu, Y. Yao, H. Gong, Q. Luo, and D. Zhu, “Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol,” J. Biomed. Opt. 21(8), 081203 (2016).
[Crossref] [PubMed]

Yun, T.

Zeng, N.

D. Chen, N. Zeng, Q. Xie, H. He, V. V. Tuchin, and H. Ma, “Mueller matrix polarimetry for characterizing microstructural variation of nude mouse skin during tissue optical clearing,” Biomed. Opt. Express 8(8), 3559–3570 (2017).
[Crossref] [PubMed]

D. Chen, N. Zeng, Y. Wang, H. He, V. V. Tuchin, and H. Ma, “Study of optical clearing in polarization measurements by Monte Carlo simulations with anisotropic tissue-mimicking models,” J. Biomed. Opt. 21(8), 081209 (2016).
[Crossref] [PubMed]

C. He, H. He, X. Li, J. Chang, Y. Wang, S. Liu, N. Zeng, Y. He, and H. Ma, “Quantitatively differentiating microstructures of tissues by frequency distributions of Mueller matrix images,” J. Biomed. Opt. 20(10), 105009 (2015).
[Crossref] [PubMed]

Y. Wang, H. He, J. Chang, N. Zeng, S. Liu, M. Li, and H. Ma, “Differentiating characteristic microstructural features of cancerous tissues using Mueller matrix microscope,” Micron 79, 8–15 (2015).
[Crossref] [PubMed]

M. Sun, H. He, N. Zeng, E. Du, Y. Guo, S. Liu, J. Wu, Y. He, and H. Ma, “Characterizing the microstructures of biological tissues using Mueller matrix and transformed polarization parameters,” Biomed. Opt. Express 5(12), 4223–4234 (2014).
[Crossref] [PubMed]

E. Du, H. He, N. Zeng, Y. Guo, R. Liao, Y. He, and H. Ma, “Two-dimensional backscattering Mueller matrix of sphere-cylinder birefringence media,” J. Biomed. Opt. 17(12), 126016 (2012).
[Crossref] [PubMed]

H. He, N. Zeng, R. Liao, T. Yun, W. Li, Y. He, and H. Ma, “Application of sphere-cylinder scattering model to skeletal muscle,” Opt. Express 18(14), 15104–15112 (2010).
[Crossref] [PubMed]

T. Yun, N. Zeng, W. Li, D. Li, X. Jiang, and H. Ma, “Monte Carlo simulation of polarized photon scattering in anisotropic media,” Opt. Express 17(19), 16590–16602 (2009).
[Crossref] [PubMed]

Zhao, S.

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

Zhu, D.

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

P. Wan, J. Zhu, J. Xu, Y. Li, T. Yu, and D. Zhu, “Evaluation of seven optical clearing methods in mouse brain,” Neurophotonics 5(3), 035007 (2018).
[Crossref] [PubMed]

W. Feng, R. Shi, N. Ma, D. K. Tuchina, V. V. Tuchin, and D. Zhu, “Skin optical clearing potential of disaccharides,” J. Biomed. Opt. 21(8), 081207 (2016).
[Crossref] [PubMed]

T. Yu, Y. Qi, J. Wang, W. Feng, J. Xu, J. Zhu, Y. Yao, H. Gong, Q. Luo, and D. Zhu, “Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol,” J. Biomed. Opt. 21(8), 081203 (2016).
[Crossref] [PubMed]

R. Shi, M. Chen, V. V. Tuchin, and D. Zhu, “Accessing to arteriovenous blood flow dynamics response using combined laser speckle contrast imaging and skin optical clearing,” Biomed. Opt. Express 6(6), 1977–1989 (2015).
[Crossref] [PubMed]

D. Zhu, K. V. Larin, Q. Luo, and V. V. Tuchin, “Recent progress in tissue optical clearing,” Laser Photonics Rev. 7(5), 732–757 (2013).
[Crossref] [PubMed]

Zhu, J.

P. Wan, J. Zhu, J. Xu, Y. Li, T. Yu, and D. Zhu, “Evaluation of seven optical clearing methods in mouse brain,” Neurophotonics 5(3), 035007 (2018).
[Crossref] [PubMed]

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

T. Yu, Y. Qi, J. Wang, W. Feng, J. Xu, J. Zhu, Y. Yao, H. Gong, Q. Luo, and D. Zhu, “Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol,” J. Biomed. Opt. 21(8), 081203 (2016).
[Crossref] [PubMed]

Zimnyakov, D. A.

V. V. Tuchin, I. L. Maksimova, D. A. Zimnyakov, I. L. Kon, A. H. Mavlyutov, and A. A. Mishin, “Light propagation in tissues with controlled optical properties,” J. Biomed. Opt. 2(4), 401–417 (1997).
[Crossref] [PubMed]

Annu. Rev. Cell Dev. Biol. (1)

K. Tainaka, A. Kuno, S. I. Kubota, T. Murakami, and H. R. Ueda, “Chemical principles in tissue clearing and staining protocols for whole-body cell profiling,” Annu. Rev. Cell Dev. Biol. 32(1), 713–741 (2016).
[Crossref] [PubMed]

Biomed. Opt. Express (3)

Biophys. J. (1)

A. Tezel and S. Mitragotri, “Interactions of inertial cavitation bubbles with stratum corneum lipid bilayers during low-frequency sonophoresis,” Biophys. J. 85(6), 3502–3512 (2003).
[Crossref] [PubMed]

Cell (1)

D. S. Richardson and J. W. Lichtman, “Clarifying tissue clearing,” Cell 162(2), 246–257 (2015).
[Crossref] [PubMed]

Cell Reports (1)

M. T. Ke, Y. Nakai, S. Fujimoto, R. Takayama, S. Yoshida, T. S. Kitajima, M. Sato, and T. Imai, “Super-resolution mapping of neuronal circuitry with an index-optimized clearing agent,” Cell Reports 14(11), 2718–2732 (2016).
[Crossref] [PubMed]

Dermatol. Surg. (1)

W. R. Lee, R. Y. Tsai, C. L. Fang, C. J. Liu, C. H. Hu, and J. Y. Fang, “Microdermabrasion as a novel tool to enhance drug delivery via the skin: an animal study,” Dermatol. Surg. 32(8), 1013–1022 (2006).
[PubMed]

Development (1)

T. Kuwajima, A. A. Sitko, P. Bhansali, C. Jurgens, W. Guido, and C. Mason, “ClearT: a detergent- and solvent-free clearing method for neuronal and non-neuronal tissue,” Development 140(6), 1364–1368 (2013).
[Crossref] [PubMed]

Expert Rev. Med. Devices (1)

E. A. Genina, A. N. Bashkatov, and V. V. Tuchin, “Tissue optical immersion clearing,” Expert Rev. Med. Devices 7(6), 825–842 (2010).
[Crossref] [PubMed]

IEEE J. Sel. Top. Quantum Electron. (1)

K. V. Larin, M. G. Ghosn, A. N. Bashkatov, E. A. Genina, N. A. Trunina, and V. V. Tuchin, “Optical clearing for OCT image enhancement and in-depth monitoring of molecular diffusion,” IEEE J. Sel. Top. Quantum Electron. 18(3), 1244–1259 (2012).
[Crossref]

J. Biomed. Opt. (11)

W. Feng, R. Shi, N. Ma, D. K. Tuchina, V. V. Tuchin, and D. Zhu, “Skin optical clearing potential of disaccharides,” J. Biomed. Opt. 21(8), 081207 (2016).
[Crossref] [PubMed]

L. Silvestri, I. Costantini, L. Sacconi, and F. S. Pavone, “Clearing of fixed tissue: a review from a microscopist’s perspective,” J. Biomed. Opt. 21(8), 081205 (2016).
[Crossref] [PubMed]

V. V. Tuchin, I. L. Maksimova, D. A. Zimnyakov, I. L. Kon, A. H. Mavlyutov, and A. A. Mishin, “Light propagation in tissues with controlled optical properties,” J. Biomed. Opt. 2(4), 401–417 (1997).
[Crossref] [PubMed]

V. V. Tuchin, “Polarized light interaction with tissues,” J. Biomed. Opt. 21(7), 71114 (2016).
[Crossref] [PubMed]

T. Yu, Y. Qi, J. Wang, W. Feng, J. Xu, J. Zhu, Y. Yao, H. Gong, Q. Luo, and D. Zhu, “Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol,” J. Biomed. Opt. 21(8), 081203 (2016).
[Crossref] [PubMed]

E. Du, H. He, N. Zeng, Y. Guo, R. Liao, Y. He, and H. Ma, “Two-dimensional backscattering Mueller matrix of sphere-cylinder birefringence media,” J. Biomed. Opt. 17(12), 126016 (2012).
[Crossref] [PubMed]

D. Chen, N. Zeng, Y. Wang, H. He, V. V. Tuchin, and H. Ma, “Study of optical clearing in polarization measurements by Monte Carlo simulations with anisotropic tissue-mimicking models,” J. Biomed. Opt. 21(8), 081209 (2016).
[Crossref] [PubMed]

C. He, H. He, X. Li, J. Chang, Y. Wang, S. Liu, N. Zeng, Y. He, and H. Ma, “Quantitatively differentiating microstructures of tissues by frequency distributions of Mueller matrix images,” J. Biomed. Opt. 20(10), 105009 (2015).
[Crossref] [PubMed]

S. Alali and A. Vitkin, “Polarized light imaging in biomedicine: emerging Mueller matrix methodologies for bulk tissue assessment,” J. Biomed. Opt. 20(6), 61104 (2015).
[Crossref] [PubMed]

S. Carvalho, N. Gueiral, E. Nogueira, R. Henrique, L. Oliveira, and V. V. Tuchin, “Glucose diffusion in colorectal mucosa-a comparative study between normal and cancer tissues,” J. Biomed. Opt. 22(9), 91506 (2017).
[Crossref] [PubMed]

V. V. Tuchin, “Coherent optical techniques for the analysis of tissue structure and dynamics,” J. Biomed. Opt. 4(1), 106–124 (1999).
[Crossref] [PubMed]

J. Biophotonics (2)

J. Qi and D. S. Elson, “Mueller polarimetric imaging for surgical and diagnostic applications: a review,” J. Biophotonics 10(8), 950–982 (2017).
[Crossref] [PubMed]

B. Kunnen, C. Macdonald, A. Doronin, S. Jacques, M. Eccles, and I. Meglinski, “Application of circularly polarized light for non-invasive diagnosis of cancerous tissues and turbid tissue-like scattering media,” J. Biophotonics 8(4), 317–323 (2015).
[Crossref] [PubMed]

J. Chem. Neuroanat. (1)

K. H. R. Jensen and R. W. Berg, “Advances and perspectives in tissue clearing using CLARITY,” J. Chem. Neuroanat. 86, 19–34 (2017).
[Crossref] [PubMed]

J. Innov. Opt. Health Sci. (1)

A. N. Bashkatov, E. A. Genina, and V. V. Tuchin, “Optical properties of skin, subcutaneous and muscle tissue: A review,” J. Innov. Opt. Health Sci. 4(1), 9–38 (2011).
[Crossref]

J. Neurosci. (1)

P. S. Tsai, J. P. Kaufhold, P. Blinder, B. Friedman, P. J. Drew, H. J. Karten, P. D. Lyden, and D. Kleinfeld, “Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels,” J. Neurosci. 29(46), 14553–14570 (2009).
[Crossref] [PubMed]

J. Phys. D Appl. Phys. (1)

A. N. Bashkatov, E. A. Genina, V. I. Kochubey, and V. V. Tuchin, “Optical properties of human skin, subcutaneous and mucous tissues in the wavelength range from 400 to 2000 nm,” J. Phys. D Appl. Phys. 38(15), 2543–2555 (2005).
[Crossref]

Laser Photonics Rev. (1)

D. Zhu, K. V. Larin, Q. Luo, and V. V. Tuchin, “Recent progress in tissue optical clearing,” Laser Photonics Rev. 7(5), 732–757 (2013).
[Crossref] [PubMed]

Laser Phys. (1)

I. V. Meglinski, D. Y. Churmakov, A. N. Bashkatov, E. A. Genina, and V. V. Tuchin, “The Enhancement of Confocal Images of Tissues at Bulk Optical Immersion,” Laser Phys. 13(1), 65–69 (2004).

Lasers Surg. Med. (2)

O. F. Stumpp, A. J. Welch, T. E. Milner, and J. Neev, “Enhancement of transepidermal skin clearing agent delivery using a 980 nm diode laser,” Lasers Surg. Med. 37(4), 278–285 (2005).
[Crossref] [PubMed]

V. V. Tuchin, G. B. Altshuler, A. A. Gavrilova, A. B. Pravdin, D. Tabatadze, J. Childs, and I. V. Yaroslavsky, “Optical clearing of skin using flash lamp-induced enhancement of epidermal permeability,” Lasers Surg. Med. 38(9), 824–836 (2006).
[Crossref] [PubMed]

Micron (1)

Y. Wang, H. He, J. Chang, N. Zeng, S. Liu, M. Li, and H. Ma, “Differentiating characteristic microstructural features of cancerous tissues using Mueller matrix microscope,” Micron 79, 8–15 (2015).
[Crossref] [PubMed]

Microvasc. Res. (1)

Y.-Y. Fu and S.-C. Tang, “Optical clearing facilitates integrated 3D visualization of mouse ileal microstructure and vascular network with high definition,” Microvasc. Res. 80(3), 512–521 (2010).
[Crossref] [PubMed]

Neurophotonics (1)

P. Wan, J. Zhu, J. Xu, Y. Li, T. Yu, and D. Zhu, “Evaluation of seven optical clearing methods in mouse brain,” Neurophotonics 5(3), 035007 (2018).
[Crossref] [PubMed]

Opt. Express (3)

Pharm. Res. (1)

A. K. Nugroho, G. L. Li, M. Danhof, and J. A. Bouwstra, “Transdermal iontophoresis of rotigotine across human stratum corneum in vitro: influence of pH and NaCl concentration,” Pharm. Res. 21(5), 844–850 (2004).
[Crossref] [PubMed]

Sci. Rep. (3)

I. Costantini, J. P. Ghobril, A. P. Di Giovanna, A. L. Allegra Mascaro, L. Silvestri, M. C. Müllenbroich, L. Onofri, V. Conti, F. Vanzi, L. Sacconi, R. Guerrini, H. Markram, G. Iannello, and F. S. Pavone, “A versatile clearing agent for multi-modal brain imaging,” Sci. Rep. 5(1), 9808 (2015).
[Crossref] [PubMed]

T. Yu, J. Zhu, Y. Li, Y. Ma, J. Wang, X. Cheng, S. Jin, Q. Sun, X. Li, H. Gong, Q. Luo, F. Xu, S. Zhao, and D. Zhu, “RTF: a rapid and versatile tissue optical clearing method,” Sci. Rep. 8(1), 1964 (2018).
[Crossref] [PubMed]

Y. Dong, H. He, W. Sheng, J. Wu, and H. Ma, “A quantitative and non-contact technique to characterise microstructural variations of skin tissues during photo-damaging process based on Mueller matrix polarimetry,” Sci. Rep. 7(1), 14702 (2017).
[Crossref] [PubMed]

Spectrochim. Acta A Mol. Biomol. Spectrosc. (1)

A. Y. Sdobnov, M. E. Darvin, E. A. Genina, A. N. Bashkatov, J. Lademann, and V. V. Tuchin, “Recent progress in tissue optical clearing for spectroscopic application,” Spectrochim. Acta A Mol. Biomol. Spectrosc. 197, 216–229 (2018).
[Crossref] [PubMed]

Other (1)

O. Nadiarnykh and P. J. Campagnola, SHG and optical clearing, in Second Harmonic Generation Imaging, F. S. Pavone, P. J. Campagnola, eds.(CRC Press, 2014), pp. 169–189.

Cited By

OSA participates in Crossref's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (10)

Fig. 1
Fig. 1 The molecular structure of formamide (a) and saturated sucrose (b).
Fig. 2
Fig. 2 Mueller matrix microscope.
Fig. 3
Fig. 3 Sphere-cylinder birefringence model (SCBM).
Fig. 4
Fig. 4 White-light images of in vitro rat skin before and after clearing by formamide (a) and saturated sucrose (b). The background is small region of 1951 USAF target.
Fig. 5
Fig. 5 Pseudo-color images of the Mueller matrix elements at three time points during clearing process using formamide(a) and saturated sucrose(b) as OCAs.
Fig. 6
Fig. 6 Pseudo-color images of the MMPD parameter: (a) depolarization parameters Δ and (b) retardation parameter δ for the unstained mouse skin tissue slice.
Fig. 7
Fig. 7 Experimental values of depolarization and retardation parameter during tissue clearing process using formamide and sucrose as OCAs.
Fig. 8
Fig. 8 Comparison of phase retardance between experimental results and Monte Carlo simulations based on one single mechanism models: (a) clearing using sucrose; (b) clearing using formamide.
Fig. 9
Fig. 9 Comparison of depolarization parameters and retardation parameter between experimental results and Monte Carlo simulations based on multiple mechanism models: (a) �� with clearing using formamide; (b) �� with clearing using formamide; (c) �� with clearing using sucrose; (d) �� with clearing using sucrose.
Fig. 10
Fig. 10 Monte Carlo simulation results of the three Mueller matrix elements: m22, m33 and m44 using sphere-cylinder birefringence model (SCBM).

Metrics