Abstract

Acetazolamide (ACZ) was used to stimulate the cerebral vasculature on ten healthy volunteers to assess the cerebral vasomotor reactivity (CVR). We have combined near infrared spectroscopy (NIRS), diffuse correlation spectroscopy (DCS) and transcranial Doppler (TCD) technologies to non-invasively assess CVR in real-time by measuring oxy- and deoxy-hemoglobin concentrations, using NIRS, local cerebral blood flow (CBF), using DCS, and blood flow velocity (CBFV) in the middle cerebral artery, using TCD. Robust and persistent increases in oxy-hemoglobin concentration, CBF and CBFV were observed. A significant agreement was found between macro-vascular (TCD) and micro-vascular (DCS) hemodynamics, between the NIRS and TCD data, and also within NIRS and DCS results. The relative cerebral metabolic rate of oxygen, rCMRO 2, was also determined, and no significant change was observed. Our results showed that the combined diffuse optics-ultrasound technique is viable to follow (CVR) and rCMRO 2 changes in adults, continuously, at the bed-side and in real time.

© 2010 OSA

Full Article  |  PDF Article

References

  • View by:
  • |
  • |
  • |

  1. N. A. Lassen, “Cerebral blood flow and oxygen consumption in man,” Physiol. Rev. 39(2), 183–238 (1959).
    [PubMed]
  2. M. Fog, “Cerebral circulation: the reaction of the pial arteries to a fall in blood pressure,” Arch. Neurol. Psychiatry 37, 351 (1937).
  3. G. I. Mchedlishvili, N. P. Mitagvaria, and L. G. Ormotsadze, “Vascular mechanisms controlling a constant blood supply to the brain (“autoregulation”),” Stroke 4(5), 742–750 (1973).
    [PubMed]
  4. B. Widder, B. Kleiser, and H. Krapf, “Course of cerebrovascular reactivity in patients with carotid artery occlusions,” Stroke 25(10), 1963–1967 (1994).
    [PubMed]
  5. S. Vorstrup, L. Henriksen, and O. B. Paulson, “Effect of acetazolamide on cerebral blood flow and cerebral metabolic rate for oxygen,” J. Clin. Invest. 74(5), 1634–1639 (1984).
    [CrossRef] [PubMed]
  6. H. W. Schytz, T. Wienecke, L. T. Jensen, J. Selb, D. A. Boas, and M. Ashina, “Changes in cerebral blood flow after acetazolamide: an experimental study comparing near-infrared spectroscopy and SPECT,” Eur. J. Neurol. 16(4), 461–467 (2009).
    [CrossRef] [PubMed]
  7. G. Settakis, C. Molnár, L. Kerényi, J. Kollár, D. Legemate, L. Csiba, and B. Fülesdi, “Acetazolamide as a vasodilatory stimulus in cerebrovascular diseases and in conditions affecting the cerebral vasculature,” Eur. J. Neurol. 10(6), 609–620 (2003).
    [CrossRef] [PubMed]
  8. A. Piepgras, P. Schmiedek, G. Leinsinger, R. L. Haberl, C. M. Kirsch, and K. M. Einhäupl, “A simple test to assess cerebrovascular reserve capacity using transcranial Doppler sonography and acetazolamide,” Stroke 21(9), 1306–1311 (1990).
    [PubMed]
  9. M. I. Chimowitz, A. J. Furlan, S. C. Jones, C. A. Sila, R. L. Lorig, L. Paranandi, and G. J. Beck, “Transcranial Doppler assessment of cerebral perfusion reserve in patients with carotid occlusive disease and no evidence of cerebral infarction,” Neurology 43(2), 353–357 (1993).
    [PubMed]
  10. W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, R. Nyberg-Hansen, D. Russell, and H. Nornes, “Effect of acetazolamide on cerebral artery blood velocity and regional cerebral blood flow in normal subjects,” Acta Neurochir. (Wien) 97(3-4), 139–145 (1989).
    [CrossRef] [PubMed]
  11. P. Démolis, G. Florence, L. Thomas, Y. R. Tran Dinh, J. F. Giudicelli, J. Seylaz, and N. J. Alkayed, “Is the acetazolamide test valid for quantitative assessment of maximal cerebral autoregulatory vasodilation? An experimental study,” Stroke 31(2), 508–515 (2000).
    [PubMed]
  12. U. Sabatini, P. Celsis, G. Viallard, A. Rascol, and J. P. Marc-Vergnes, “Quantitative assessment of cerebral blood volume by single-photon emission computed tomography,” Stroke 22(3), 324–330 (1991).
    [PubMed]
  13. H. Yamaguchi, H. Yamauchi, S. Hazama, H. Hamamoto, and N. Inoue, “Correlation between cerebral oxygen metabolism and cerebral blood flow simultaneously measured before and after acetazolamide administration,” J. Biomed. Opt. 4(4), 418 (1999).
    [CrossRef]
  14. Y. F. Yen, A. S. Field, E. M. Martin, N. Ari, J. H. Burdette, D. M. Moody, and A. M. Takahashi, “Test-retest reproducibility of quantitative CBF measurements using FAIR perfusion MRI and acetazolamide challenge,” Magn. Reson. Med. 47(5), 921–928 (2002).
    [CrossRef] [PubMed]
  15. J. A. Detre, O. B. Samuels, D. C. Alsop, J. B. Gonzalez-At, S. E. Kasner, and E. C. Raps, “Noninvasive magnetic resonance imaging evaluation of cerebral blood flow with acetazolamide challenge in patients with cerebrovascular stenosis,” J. Magn. Reson. Imaging 10(5), 870–875 (1999).
    [CrossRef] [PubMed]
  16. B. Weber, G. Westera, V. Treyer, C. Burger, N. Khan, and A. Buck, “Constant-infusion H(2)15O PET and acetazolamide challenge in the assessment of cerebral perfusion status,” J. Nucl. Med. 45(8), 1344–1350 (2004).
    [PubMed]
  17. M. Matteis, E. Troisi, B. C. Monaldo, C. Caltagirone, and M. Silvestrini, “Age and sex differences in cerebral hemodynamics: a transcranial Doppler study,” Stroke 29(5), 963–967 (1998).
    [PubMed]
  18. B. M. Eicke, E. Buss, R. R. Bähr, G. Hajak, and W. Paulus, “Influence of acetazolamide and CO2 on extracranial flow volume and intracranial blood flow velocity,” Stroke 30(1), 76–80 (1999).
    [PubMed]
  19. B. Fülesdi, M. Limburg, L. Oláh, D. Bereczki, L. Csiba, and J. Kollár, “Lack of gender difference in acetazolamide-induced cerebral vasomotor reactivity in patients suffering from type-1 diabetes mellitus,” Acta Diabetol. 38(3), 107–112 (2001).
    [CrossRef] [PubMed]
  20. A. Villringer and B. Chance, “Non-invasive optical spectroscopy and imaging of human brain function,” Trends Neurosci. 20(10), 435–442 (1997).
    [CrossRef] [PubMed]
  21. E. M. Hillman, “Optical brain imaging in vivo: techniques and applications from animal to man,” J. Biomed. Opt. 12(5), 051402 (2007).
    [CrossRef] [PubMed]
  22. T. Durduran, R. Choe, W. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010).
    [CrossRef]
  23. E. Keller, M. Wolf, M. Martin, and Y. Yonekawa, “Estimation of cerebral oxygenation and hemodynamics in cerebral vasospasm using indocyaningreen dye dilution and near infrared spectroscopy: a case report,” J. Neurosurg. Anesthesiol. 13(1), 43–48 (2001).
    [CrossRef] [PubMed]
  24. B. P. Wagner, S. Gertsch, R. A. Ammann, and J. Pfenninger, “Reproducibility of the blood flow index as noninvasive, bedside estimation of cerebral blood flow,” Intensive Care Med. 29(2), 196–200 (2003).
    [PubMed]
  25. D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003).
    [CrossRef] [PubMed]
  26. I. Tachtsidis, T. Leung, D. Delpy, C. Elwell, M. Tisdall, and M. Smith, “Cerebral blood flow assessment with indocyanine green bolus transit detection by near-infrared spectroscopy before and after acetazolamide challenge in humans,” Biomedical Optics (2006).
  27. M. Kaminogo, A. Ichikura, S. Shibata, T. Toba, and M. Yonekura, “Effect of acetazolamide on regional cerebral oxygen saturation and regional cerebral blood flow,” Stroke 26(12), 2358–2360 (1995).
    [PubMed]
  28. M. Holzschuh, C. Woertgen, C. Metz, and A. Brawanski, “Comparison of changes in cerebral blood flow and cerebral oxygen saturation measured by near infrared spectroscopy (NIRS) after acetazolamide,” Acta Neurochir. (Wien) 139(1), 58–62 (1997).
    [CrossRef] [PubMed]
  29. D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and imaging with diffusing temporal field correlations,” Phys. Rev. Lett. 75(9), 1855–1858 (1995).
    [CrossRef] [PubMed]
  30. D. Boas and A. Yodh, “Spatially varying dynamical properties of turbid media probed with diffusing temporal light correlation,” J. Opt. Soc. Am. A 14(1), 192–215 (1997).
    [CrossRef]
  31. E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
    [CrossRef] [PubMed]
  32. N. Roche-Labarbe, F. Wallois, E. Ponchel, G. Kongolo, and R. Grebe, “Coupled oxygenation oscillation measured by NIRS and intermittent cerebral activation on EEG in premature infants,” Neuroimage 36(3), 718–727 (2007).
    [CrossRef] [PubMed]
  33. T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse optical measurement of blood flow, blood oxygenation, and metabolism in a human brain during sensorimotor cortex activation,” Opt. Lett. 29(15), 1766–1768 (2004).
    [CrossRef] [PubMed]
  34. J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J. Biomed. Opt. 10(4), 044002 (2005).
    [CrossRef] [PubMed]
  35. T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
    [CrossRef] [PubMed]
  36. M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
    [CrossRef] [PubMed]
  37. T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, “Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients,” Opt. Express 17(5), 3884–3902 (2009).
    [CrossRef] [PubMed]
  38. A. L. Carney and E. M. Anderson, “The system approach to brain blood flow,” Adv. Neurol. 30, 1–30 (1981).
    [PubMed]
  39. R. Roski, R. F. Spetzler, M. Owen, K. Chandar, J. G. Sholl, and F. E. Nulsen, “Reversal of seven-year old visual field defect with extracranial-intracranial arterial anastomosis,” Surg. Neurol. 10(4), 267–268 (1978).
    [PubMed]
  40. P. Frykholm, J. L. R. Andersson, J. Valtysson, H. C. Silander, L. Hillered, L. Persson, Y. Olsson, W. R. Yu, G. Westerberg, Y. Watanabe, B. Långström, and P. Enblad, “A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion-reperfusion primate model,” Acta Neurol. Scand. 102(1), 18–26 (2000).
    [CrossRef] [PubMed]
  41. J. B. Posner and F. Plum, “The toxic effects of carbon dioxide and acetazolamide in hepatic encephalopathy,” J. Clin. Invest. 39(8), 1246–1258 (1960).
    [CrossRef] [PubMed]
  42. B. E. Laux and M. E. Raichle, “The effect of acetazolamide on cerebral blood flow and oxygen utilization in the rhesus monkey,” J. Clin. Invest. 62(3), 585–592 (1978).
    [CrossRef] [PubMed]
  43. B. Kleiser and B. Widder, “Course of carotid artery occlusions with impaired cerebrovascular reactivity,” Stroke 23(2), 171–174 (1992).
    [PubMed]
  44. W. J. Powers, L. W. Tempel, and R. L. Grubb., “Influence of cerebral hemodynamics on stroke risk: one-year follow-up of 30 medically treated patients,” Ann. Neurol. 25(4), 325–330 (1989).
    [CrossRef] [PubMed]
  45. D. L. Ehrenreich, R. A. Burns, R. W. Alman, and J. F. Fazekas, “Influence of acetazolamide on cerebral blood flow,” Arch. Neurol. 5, 227–232 (1961).
    [PubMed]
  46. J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003).
    [CrossRef] [PubMed]
  47. V. Toronov, E. D’Amico, D. Hueber, E. Gratton, B. Barbieri, and A. Webb, “Optimization of the signal-to-noise ratio of frequency-domain instrumentation for near-infrared spectro-imaging of the human brain,” Opt. Express 11(21), 2717–2729 (2003).
    [CrossRef] [PubMed]
  48. S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys. Med. Biol. 37(7), 1531–1560 (1992).
    [CrossRef] [PubMed]
  49. P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Roth, E. O. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult head, calf and forearm and the head of the newborn infant as a function of inter optode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
    [PubMed]
  50. G. Strangman, M. A. Franceschini, and D. A. Boas, “Factors affecting the accuracy of near-infrared spectroscopy concentration calculations for focal changes in oxygenation parameters,” Neuroimage 18(4), 865–879 (2003).
    [CrossRef] [PubMed]
  51. A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304 (1995).
    [CrossRef] [PubMed]
  52. S. Kohri, Y. Hoshi, M. Tamura, C. Kato, Y. Kuge, and N. Tamaki, “Quantitative evaluation of the relative contribution ratio of cerebral tissue to near-infrared signals in the adult human head: a preliminary study,” Physiol. Meas. 23(2), 301–312 (2002).
    [CrossRef] [PubMed]
  53. J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001).
    [CrossRef] [PubMed]
  54. A. Torricelli, A. Pifferi, P. Taroni, E. Giambattistelli, and R. Cubeddu, “In vivo optical characterization of human tissues from 610 to 1010 nm by time-resolved reflectance spectroscopy,” Phys. Med. Biol. 46(8), 2227–2237 (2001).
    [CrossRef] [PubMed]
  55. K. Hornik, “The R FAQ,” (2010). ISBN 3–900051–08–9.
  56. R. L. Grubb, M. E. Raichle, J. O. Eichling, and M. M. Ter-Pogossian, “The effects of changes in PaCO2 on cerebral blood volume, blood flow, and vascular mean transit time,” Stroke 5(5), 630–639 (1974).
    [PubMed]
  57. T. S. Leung, I. Tachtsidis, M. M. Tisdall, C. Pritchard, M. Smith, and C. E. Elwell, “Estimating a modified Grubb’s exponent in healthy human brains with near infrared spectroscopy and transcranial Doppler,” Physiol. Meas. 30(1), 1–12 (2009).
    [CrossRef] [PubMed]
  58. P. T. Ulrich, T. Becker, and O. S. Kempski, “Correlation of cerebral blood flow and MCA flow velocity measured in healthy volunteers during acetazolamide and CO2 stimulation,” J. Neurol. Sci. 129(2), 120–130 (1995).
    [CrossRef] [PubMed]
  59. A. Dahl, K. F. Lindegaard, D. Russell, R. Nyberg-Hansen, K. Rootwelt, W. Sorteberg, and H. Nornes, “A comparison of transcranial Doppler and cerebral blood flow studies to assess cerebral vasoreactivity,” Stroke 23(1), 15–19 (1992).
    [PubMed]
  60. T. Kreisig, P. Schmiedek, G. Leinsinger, K. Einhäupl, and E. Moser, “[133Xe-DSPECT: normal values of resting cerebral blood flow and reserve capacity],” Nucl. Med. (Stuttg.) 26(5), 192–197 (1987).
    [PubMed]
  61. A. Dahl, D. Russell, R. Nyberg-Hansen, K. Rootwelt, and P. Mowinckel, “Simultaneous assessment of vasoreactivity using transcranial Doppler ultrasound and cerebral blood flow in healthy subjects,” J. Cereb. Blood Flow Metab. 14(6), 974–981 (1994).
    [PubMed]
  62. I. Tachtsidis, M. Tisdall, D. T. Delpy, M. Smith, and C. E. Elwell, “Measurement of cerebral tissue oxygenation in young healthy volunteers during acetazolamide provocation: a transcranial Doppler and near-infrared spectroscopy investigation,” Adv. Exp. Med. Biol. 614, 389–396 (2008).
    [CrossRef] [PubMed]
  63. E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
    [CrossRef] [PubMed]
  64. N. Roche-Labarbe, S. A. Carp, A. Surova, M. Patel, D. A. Boas, P. E. Grant, and M. A. Franceschini, “Noninvasive optical measures of CBV, StO(2), CBF index, and rCMRO(2) in human premature neonates’ brains in the first six weeks of life,” Hum. Brain Mapp. 31(3), 341–352 (2010).
    [PubMed]
  65. W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, D. Russell, R. Nyberg-Hansen, and H. Nornes, “Blood velocity and regional blood flow in defined cerebral artery systems,” Acta Neurochir. (Wien) 97(1-2), 47–52 (1989).
    [CrossRef] [PubMed]
  66. H. A. Kontos, “Validity of cerebral arterial blood flow calculations from velocity measurements,” Stroke 20(1), 1–3 (1989).
    [PubMed]
  67. T. L. Davis, K. K. Kwong, R. M. Weisskoff, and B. R. Rosen, “Calibrated functional MRI: mapping the dynamics of oxidative metabolism,” Proc. Natl. Acad. Sci. U.S.A. 95(4), 1834–1839 (1998).
    [CrossRef] [PubMed]
  68. R. D. Hoge, J. Atkinson, B. Gill, G. R. Crelier, S. Marrett, and G. B. Pike, “Linear coupling between cerebral blood flow and oxygen consumption in activated human cortex,” Proc. Natl. Acad. Sci. U.S.A. 96(16), 9403–9408 (1999).
    [CrossRef] [PubMed]
  69. S. G. Kim, E. Rostrup, H. B. Larsson, S. Ogawa, and O. B. Paulson, “Determination of relative CMRO2 from CBF and BOLD changes: significant increase of oxygen consumption rate during visual stimulation,” Magn. Reson. Med. 41(6), 1152–1161 (1999).
    [CrossRef] [PubMed]
  70. S. Carp, G. Dai, D. Boas, M. Franceschini, and Y. Kim, “Validation of diffuse correlation spectroscopy measurements of rodent cerebral blood flow with simultaneous arterial spin labeling mri; towards mri-optical continuous cerebral metabolic monitoring,” Biomed. Opt. Express 1(2), 553–565 (2010).
    [CrossRef]
  71. L. Gagnon, M. Desjardins, J. Jehanne-Lacasse, L. Bherer, and F. Lesage, “Investigation of diffuse correlation spectroscopy in multi-layered media including the human head,” Opt. Express 16(20), 15514–15530 (2008).
    [CrossRef] [PubMed]
  72. M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
    [CrossRef] [PubMed]
  73. M. L. Dyken, E. Klatte, O. J. Kolar, and C. Surgeon, “Complete occlusion of common or internal carotid arteries. Clinical significance,” Arch. Neurol. 30(5), 343–346 (1974).
    [PubMed]
  74. R. Cote, H. J. Barnett, and D. W. Taylor, “Internal carotid occlusion: a prospective study,” Stroke 14(6), 898–902 (1983).
    [PubMed]
  75. S. Durham, H. Smith, M. Rutigliano, and H. Yonas, “Assessment of cerebral vasoreactivity and stroke risk using Xe-CT acetazolamide challenge,” Stroke 22, 138 (1991).

2010 (6)

T. Durduran, R. Choe, W. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010).
[CrossRef]

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

N. Roche-Labarbe, S. A. Carp, A. Surova, M. Patel, D. A. Boas, P. E. Grant, and M. A. Franceschini, “Noninvasive optical measures of CBV, StO(2), CBF index, and rCMRO(2) in human premature neonates’ brains in the first six weeks of life,” Hum. Brain Mapp. 31(3), 341–352 (2010).
[PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

S. Carp, G. Dai, D. Boas, M. Franceschini, and Y. Kim, “Validation of diffuse correlation spectroscopy measurements of rodent cerebral blood flow with simultaneous arterial spin labeling mri; towards mri-optical continuous cerebral metabolic monitoring,” Biomed. Opt. Express 1(2), 553–565 (2010).
[CrossRef]

2009 (5)

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, “Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients,” Opt. Express 17(5), 3884–3902 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

T. S. Leung, I. Tachtsidis, M. M. Tisdall, C. Pritchard, M. Smith, and C. E. Elwell, “Estimating a modified Grubb’s exponent in healthy human brains with near infrared spectroscopy and transcranial Doppler,” Physiol. Meas. 30(1), 1–12 (2009).
[CrossRef] [PubMed]

H. W. Schytz, T. Wienecke, L. T. Jensen, J. Selb, D. A. Boas, and M. Ashina, “Changes in cerebral blood flow after acetazolamide: an experimental study comparing near-infrared spectroscopy and SPECT,” Eur. J. Neurol. 16(4), 461–467 (2009).
[CrossRef] [PubMed]

2008 (2)

I. Tachtsidis, M. Tisdall, D. T. Delpy, M. Smith, and C. E. Elwell, “Measurement of cerebral tissue oxygenation in young healthy volunteers during acetazolamide provocation: a transcranial Doppler and near-infrared spectroscopy investigation,” Adv. Exp. Med. Biol. 614, 389–396 (2008).
[CrossRef] [PubMed]

L. Gagnon, M. Desjardins, J. Jehanne-Lacasse, L. Bherer, and F. Lesage, “Investigation of diffuse correlation spectroscopy in multi-layered media including the human head,” Opt. Express 16(20), 15514–15530 (2008).
[CrossRef] [PubMed]

2007 (2)

N. Roche-Labarbe, F. Wallois, E. Ponchel, G. Kongolo, and R. Grebe, “Coupled oxygenation oscillation measured by NIRS and intermittent cerebral activation on EEG in premature infants,” Neuroimage 36(3), 718–727 (2007).
[CrossRef] [PubMed]

E. M. Hillman, “Optical brain imaging in vivo: techniques and applications from animal to man,” J. Biomed. Opt. 12(5), 051402 (2007).
[CrossRef] [PubMed]

2005 (1)

J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J. Biomed. Opt. 10(4), 044002 (2005).
[CrossRef] [PubMed]

2004 (2)

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse optical measurement of blood flow, blood oxygenation, and metabolism in a human brain during sensorimotor cortex activation,” Opt. Lett. 29(15), 1766–1768 (2004).
[CrossRef] [PubMed]

B. Weber, G. Westera, V. Treyer, C. Burger, N. Khan, and A. Buck, “Constant-infusion H(2)15O PET and acetazolamide challenge in the assessment of cerebral perfusion status,” J. Nucl. Med. 45(8), 1344–1350 (2004).
[PubMed]

2003 (6)

G. Settakis, C. Molnár, L. Kerényi, J. Kollár, D. Legemate, L. Csiba, and B. Fülesdi, “Acetazolamide as a vasodilatory stimulus in cerebrovascular diseases and in conditions affecting the cerebral vasculature,” Eur. J. Neurol. 10(6), 609–620 (2003).
[CrossRef] [PubMed]

B. P. Wagner, S. Gertsch, R. A. Ammann, and J. Pfenninger, “Reproducibility of the blood flow index as noninvasive, bedside estimation of cerebral blood flow,” Intensive Care Med. 29(2), 196–200 (2003).
[PubMed]

D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003).
[CrossRef] [PubMed]

V. Toronov, E. D’Amico, D. Hueber, E. Gratton, B. Barbieri, and A. Webb, “Optimization of the signal-to-noise ratio of frequency-domain instrumentation for near-infrared spectro-imaging of the human brain,” Opt. Express 11(21), 2717–2729 (2003).
[CrossRef] [PubMed]

J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003).
[CrossRef] [PubMed]

G. Strangman, M. A. Franceschini, and D. A. Boas, “Factors affecting the accuracy of near-infrared spectroscopy concentration calculations for focal changes in oxygenation parameters,” Neuroimage 18(4), 865–879 (2003).
[CrossRef] [PubMed]

2002 (2)

S. Kohri, Y. Hoshi, M. Tamura, C. Kato, Y. Kuge, and N. Tamaki, “Quantitative evaluation of the relative contribution ratio of cerebral tissue to near-infrared signals in the adult human head: a preliminary study,” Physiol. Meas. 23(2), 301–312 (2002).
[CrossRef] [PubMed]

Y. F. Yen, A. S. Field, E. M. Martin, N. Ari, J. H. Burdette, D. M. Moody, and A. M. Takahashi, “Test-retest reproducibility of quantitative CBF measurements using FAIR perfusion MRI and acetazolamide challenge,” Magn. Reson. Med. 47(5), 921–928 (2002).
[CrossRef] [PubMed]

2001 (4)

E. Keller, M. Wolf, M. Martin, and Y. Yonekawa, “Estimation of cerebral oxygenation and hemodynamics in cerebral vasospasm using indocyaningreen dye dilution and near infrared spectroscopy: a case report,” J. Neurosurg. Anesthesiol. 13(1), 43–48 (2001).
[CrossRef] [PubMed]

B. Fülesdi, M. Limburg, L. Oláh, D. Bereczki, L. Csiba, and J. Kollár, “Lack of gender difference in acetazolamide-induced cerebral vasomotor reactivity in patients suffering from type-1 diabetes mellitus,” Acta Diabetol. 38(3), 107–112 (2001).
[CrossRef] [PubMed]

J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001).
[CrossRef] [PubMed]

A. Torricelli, A. Pifferi, P. Taroni, E. Giambattistelli, and R. Cubeddu, “In vivo optical characterization of human tissues from 610 to 1010 nm by time-resolved reflectance spectroscopy,” Phys. Med. Biol. 46(8), 2227–2237 (2001).
[CrossRef] [PubMed]

2000 (2)

P. Frykholm, J. L. R. Andersson, J. Valtysson, H. C. Silander, L. Hillered, L. Persson, Y. Olsson, W. R. Yu, G. Westerberg, Y. Watanabe, B. Långström, and P. Enblad, “A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion-reperfusion primate model,” Acta Neurol. Scand. 102(1), 18–26 (2000).
[CrossRef] [PubMed]

P. Démolis, G. Florence, L. Thomas, Y. R. Tran Dinh, J. F. Giudicelli, J. Seylaz, and N. J. Alkayed, “Is the acetazolamide test valid for quantitative assessment of maximal cerebral autoregulatory vasodilation? An experimental study,” Stroke 31(2), 508–515 (2000).
[PubMed]

1999 (5)

H. Yamaguchi, H. Yamauchi, S. Hazama, H. Hamamoto, and N. Inoue, “Correlation between cerebral oxygen metabolism and cerebral blood flow simultaneously measured before and after acetazolamide administration,” J. Biomed. Opt. 4(4), 418 (1999).
[CrossRef]

J. A. Detre, O. B. Samuels, D. C. Alsop, J. B. Gonzalez-At, S. E. Kasner, and E. C. Raps, “Noninvasive magnetic resonance imaging evaluation of cerebral blood flow with acetazolamide challenge in patients with cerebrovascular stenosis,” J. Magn. Reson. Imaging 10(5), 870–875 (1999).
[CrossRef] [PubMed]

B. M. Eicke, E. Buss, R. R. Bähr, G. Hajak, and W. Paulus, “Influence of acetazolamide and CO2 on extracranial flow volume and intracranial blood flow velocity,” Stroke 30(1), 76–80 (1999).
[PubMed]

R. D. Hoge, J. Atkinson, B. Gill, G. R. Crelier, S. Marrett, and G. B. Pike, “Linear coupling between cerebral blood flow and oxygen consumption in activated human cortex,” Proc. Natl. Acad. Sci. U.S.A. 96(16), 9403–9408 (1999).
[CrossRef] [PubMed]

S. G. Kim, E. Rostrup, H. B. Larsson, S. Ogawa, and O. B. Paulson, “Determination of relative CMRO2 from CBF and BOLD changes: significant increase of oxygen consumption rate during visual stimulation,” Magn. Reson. Med. 41(6), 1152–1161 (1999).
[CrossRef] [PubMed]

1998 (2)

T. L. Davis, K. K. Kwong, R. M. Weisskoff, and B. R. Rosen, “Calibrated functional MRI: mapping the dynamics of oxidative metabolism,” Proc. Natl. Acad. Sci. U.S.A. 95(4), 1834–1839 (1998).
[CrossRef] [PubMed]

M. Matteis, E. Troisi, B. C. Monaldo, C. Caltagirone, and M. Silvestrini, “Age and sex differences in cerebral hemodynamics: a transcranial Doppler study,” Stroke 29(5), 963–967 (1998).
[PubMed]

1997 (3)

A. Villringer and B. Chance, “Non-invasive optical spectroscopy and imaging of human brain function,” Trends Neurosci. 20(10), 435–442 (1997).
[CrossRef] [PubMed]

M. Holzschuh, C. Woertgen, C. Metz, and A. Brawanski, “Comparison of changes in cerebral blood flow and cerebral oxygen saturation measured by near infrared spectroscopy (NIRS) after acetazolamide,” Acta Neurochir. (Wien) 139(1), 58–62 (1997).
[CrossRef] [PubMed]

D. Boas and A. Yodh, “Spatially varying dynamical properties of turbid media probed with diffusing temporal light correlation,” J. Opt. Soc. Am. A 14(1), 192–215 (1997).
[CrossRef]

1995 (4)

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304 (1995).
[CrossRef] [PubMed]

P. T. Ulrich, T. Becker, and O. S. Kempski, “Correlation of cerebral blood flow and MCA flow velocity measured in healthy volunteers during acetazolamide and CO2 stimulation,” J. Neurol. Sci. 129(2), 120–130 (1995).
[CrossRef] [PubMed]

D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and imaging with diffusing temporal field correlations,” Phys. Rev. Lett. 75(9), 1855–1858 (1995).
[CrossRef] [PubMed]

M. Kaminogo, A. Ichikura, S. Shibata, T. Toba, and M. Yonekura, “Effect of acetazolamide on regional cerebral oxygen saturation and regional cerebral blood flow,” Stroke 26(12), 2358–2360 (1995).
[PubMed]

1994 (2)

B. Widder, B. Kleiser, and H. Krapf, “Course of cerebrovascular reactivity in patients with carotid artery occlusions,” Stroke 25(10), 1963–1967 (1994).
[PubMed]

A. Dahl, D. Russell, R. Nyberg-Hansen, K. Rootwelt, and P. Mowinckel, “Simultaneous assessment of vasoreactivity using transcranial Doppler ultrasound and cerebral blood flow in healthy subjects,” J. Cereb. Blood Flow Metab. 14(6), 974–981 (1994).
[PubMed]

1993 (1)

M. I. Chimowitz, A. J. Furlan, S. C. Jones, C. A. Sila, R. L. Lorig, L. Paranandi, and G. J. Beck, “Transcranial Doppler assessment of cerebral perfusion reserve in patients with carotid occlusive disease and no evidence of cerebral infarction,” Neurology 43(2), 353–357 (1993).
[PubMed]

1992 (4)

B. Kleiser and B. Widder, “Course of carotid artery occlusions with impaired cerebrovascular reactivity,” Stroke 23(2), 171–174 (1992).
[PubMed]

A. Dahl, K. F. Lindegaard, D. Russell, R. Nyberg-Hansen, K. Rootwelt, W. Sorteberg, and H. Nornes, “A comparison of transcranial Doppler and cerebral blood flow studies to assess cerebral vasoreactivity,” Stroke 23(1), 15–19 (1992).
[PubMed]

S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys. Med. Biol. 37(7), 1531–1560 (1992).
[CrossRef] [PubMed]

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Roth, E. O. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult head, calf and forearm and the head of the newborn infant as a function of inter optode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[PubMed]

1991 (2)

S. Durham, H. Smith, M. Rutigliano, and H. Yonas, “Assessment of cerebral vasoreactivity and stroke risk using Xe-CT acetazolamide challenge,” Stroke 22, 138 (1991).

U. Sabatini, P. Celsis, G. Viallard, A. Rascol, and J. P. Marc-Vergnes, “Quantitative assessment of cerebral blood volume by single-photon emission computed tomography,” Stroke 22(3), 324–330 (1991).
[PubMed]

1990 (1)

A. Piepgras, P. Schmiedek, G. Leinsinger, R. L. Haberl, C. M. Kirsch, and K. M. Einhäupl, “A simple test to assess cerebrovascular reserve capacity using transcranial Doppler sonography and acetazolamide,” Stroke 21(9), 1306–1311 (1990).
[PubMed]

1989 (4)

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, R. Nyberg-Hansen, D. Russell, and H. Nornes, “Effect of acetazolamide on cerebral artery blood velocity and regional cerebral blood flow in normal subjects,” Acta Neurochir. (Wien) 97(3-4), 139–145 (1989).
[CrossRef] [PubMed]

W. J. Powers, L. W. Tempel, and R. L. Grubb., “Influence of cerebral hemodynamics on stroke risk: one-year follow-up of 30 medically treated patients,” Ann. Neurol. 25(4), 325–330 (1989).
[CrossRef] [PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, D. Russell, R. Nyberg-Hansen, and H. Nornes, “Blood velocity and regional blood flow in defined cerebral artery systems,” Acta Neurochir. (Wien) 97(1-2), 47–52 (1989).
[CrossRef] [PubMed]

H. A. Kontos, “Validity of cerebral arterial blood flow calculations from velocity measurements,” Stroke 20(1), 1–3 (1989).
[PubMed]

1987 (1)

T. Kreisig, P. Schmiedek, G. Leinsinger, K. Einhäupl, and E. Moser, “[133Xe-DSPECT: normal values of resting cerebral blood flow and reserve capacity],” Nucl. Med. (Stuttg.) 26(5), 192–197 (1987).
[PubMed]

1984 (1)

S. Vorstrup, L. Henriksen, and O. B. Paulson, “Effect of acetazolamide on cerebral blood flow and cerebral metabolic rate for oxygen,” J. Clin. Invest. 74(5), 1634–1639 (1984).
[CrossRef] [PubMed]

1983 (1)

R. Cote, H. J. Barnett, and D. W. Taylor, “Internal carotid occlusion: a prospective study,” Stroke 14(6), 898–902 (1983).
[PubMed]

1981 (1)

A. L. Carney and E. M. Anderson, “The system approach to brain blood flow,” Adv. Neurol. 30, 1–30 (1981).
[PubMed]

1978 (2)

R. Roski, R. F. Spetzler, M. Owen, K. Chandar, J. G. Sholl, and F. E. Nulsen, “Reversal of seven-year old visual field defect with extracranial-intracranial arterial anastomosis,” Surg. Neurol. 10(4), 267–268 (1978).
[PubMed]

B. E. Laux and M. E. Raichle, “The effect of acetazolamide on cerebral blood flow and oxygen utilization in the rhesus monkey,” J. Clin. Invest. 62(3), 585–592 (1978).
[CrossRef] [PubMed]

1974 (2)

R. L. Grubb, M. E. Raichle, J. O. Eichling, and M. M. Ter-Pogossian, “The effects of changes in PaCO2 on cerebral blood volume, blood flow, and vascular mean transit time,” Stroke 5(5), 630–639 (1974).
[PubMed]

M. L. Dyken, E. Klatte, O. J. Kolar, and C. Surgeon, “Complete occlusion of common or internal carotid arteries. Clinical significance,” Arch. Neurol. 30(5), 343–346 (1974).
[PubMed]

1973 (1)

G. I. Mchedlishvili, N. P. Mitagvaria, and L. G. Ormotsadze, “Vascular mechanisms controlling a constant blood supply to the brain (“autoregulation”),” Stroke 4(5), 742–750 (1973).
[PubMed]

1961 (1)

D. L. Ehrenreich, R. A. Burns, R. W. Alman, and J. F. Fazekas, “Influence of acetazolamide on cerebral blood flow,” Arch. Neurol. 5, 227–232 (1961).
[PubMed]

1960 (1)

J. B. Posner and F. Plum, “The toxic effects of carbon dioxide and acetazolamide in hepatic encephalopathy,” J. Clin. Invest. 39(8), 1246–1258 (1960).
[CrossRef] [PubMed]

1959 (1)

N. A. Lassen, “Cerebral blood flow and oxygen consumption in man,” Physiol. Rev. 39(2), 183–238 (1959).
[PubMed]

1937 (1)

M. Fog, “Cerebral circulation: the reaction of the pial arteries to a fall in blood pressure,” Arch. Neurol. Psychiatry 37, 351 (1937).

Alkayed, N. J.

P. Démolis, G. Florence, L. Thomas, Y. R. Tran Dinh, J. F. Giudicelli, J. Seylaz, and N. J. Alkayed, “Is the acetazolamide test valid for quantitative assessment of maximal cerebral autoregulatory vasodilation? An experimental study,” Stroke 31(2), 508–515 (2000).
[PubMed]

Alman, R. W.

D. L. Ehrenreich, R. A. Burns, R. W. Alman, and J. F. Fazekas, “Influence of acetazolamide on cerebral blood flow,” Arch. Neurol. 5, 227–232 (1961).
[PubMed]

Alsop, D. C.

J. A. Detre, O. B. Samuels, D. C. Alsop, J. B. Gonzalez-At, S. E. Kasner, and E. C. Raps, “Noninvasive magnetic resonance imaging evaluation of cerebral blood flow with acetazolamide challenge in patients with cerebrovascular stenosis,” J. Magn. Reson. Imaging 10(5), 870–875 (1999).
[CrossRef] [PubMed]

Ammann, R. A.

B. P. Wagner, S. Gertsch, R. A. Ammann, and J. Pfenninger, “Reproducibility of the blood flow index as noninvasive, bedside estimation of cerebral blood flow,” Intensive Care Med. 29(2), 196–200 (2003).
[PubMed]

Anderson, E. M.

A. L. Carney and E. M. Anderson, “The system approach to brain blood flow,” Adv. Neurol. 30, 1–30 (1981).
[PubMed]

Andersson, J. L. R.

P. Frykholm, J. L. R. Andersson, J. Valtysson, H. C. Silander, L. Hillered, L. Persson, Y. Olsson, W. R. Yu, G. Westerberg, Y. Watanabe, B. Långström, and P. Enblad, “A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion-reperfusion primate model,” Acta Neurol. Scand. 102(1), 18–26 (2000).
[CrossRef] [PubMed]

Arger, P. H.

Ari, N.

Y. F. Yen, A. S. Field, E. M. Martin, N. Ari, J. H. Burdette, D. M. Moody, and A. M. Takahashi, “Test-retest reproducibility of quantitative CBF measurements using FAIR perfusion MRI and acetazolamide challenge,” Magn. Reson. Med. 47(5), 921–928 (2002).
[CrossRef] [PubMed]

Arridge, S. R.

S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys. Med. Biol. 37(7), 1531–1560 (1992).
[CrossRef] [PubMed]

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Roth, E. O. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult head, calf and forearm and the head of the newborn infant as a function of inter optode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[PubMed]

Ashina, M.

H. W. Schytz, T. Wienecke, L. T. Jensen, J. Selb, D. A. Boas, and M. Ashina, “Changes in cerebral blood flow after acetazolamide: an experimental study comparing near-infrared spectroscopy and SPECT,” Eur. J. Neurol. 16(4), 461–467 (2009).
[CrossRef] [PubMed]

Atkinson, J.

R. D. Hoge, J. Atkinson, B. Gill, G. R. Crelier, S. Marrett, and G. B. Pike, “Linear coupling between cerebral blood flow and oxygen consumption in activated human cortex,” Proc. Natl. Acad. Sci. U.S.A. 96(16), 9403–9408 (1999).
[CrossRef] [PubMed]

Bähr, R. R.

B. M. Eicke, E. Buss, R. R. Bähr, G. Hajak, and W. Paulus, “Influence of acetazolamide and CO2 on extracranial flow volume and intracranial blood flow velocity,” Stroke 30(1), 76–80 (1999).
[PubMed]

Baker, W.

T. Durduran, R. Choe, W. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010).
[CrossRef]

Barbieri, B.

Barnett, H. J.

R. Cote, H. J. Barnett, and D. W. Taylor, “Internal carotid occlusion: a prospective study,” Stroke 14(6), 898–902 (1983).
[PubMed]

Beck, G. J.

M. I. Chimowitz, A. J. Furlan, S. C. Jones, C. A. Sila, R. L. Lorig, L. Paranandi, and G. J. Beck, “Transcranial Doppler assessment of cerebral perfusion reserve in patients with carotid occlusive disease and no evidence of cerebral infarction,” Neurology 43(2), 353–357 (1993).
[PubMed]

Becker, T.

P. T. Ulrich, T. Becker, and O. S. Kempski, “Correlation of cerebral blood flow and MCA flow velocity measured in healthy volunteers during acetazolamide and CO2 stimulation,” J. Neurol. Sci. 129(2), 120–130 (1995).
[CrossRef] [PubMed]

Bereczki, D.

B. Fülesdi, M. Limburg, L. Oláh, D. Bereczki, L. Csiba, and J. Kollár, “Lack of gender difference in acetazolamide-induced cerebral vasomotor reactivity in patients suffering from type-1 diabetes mellitus,” Acta Diabetol. 38(3), 107–112 (2001).
[CrossRef] [PubMed]

Berwick, J.

J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001).
[CrossRef] [PubMed]

Bherer, L.

Boas, D.

Boas, D. A.

N. Roche-Labarbe, S. A. Carp, A. Surova, M. Patel, D. A. Boas, P. E. Grant, and M. A. Franceschini, “Noninvasive optical measures of CBV, StO(2), CBF index, and rCMRO(2) in human premature neonates’ brains in the first six weeks of life,” Hum. Brain Mapp. 31(3), 341–352 (2010).
[PubMed]

H. W. Schytz, T. Wienecke, L. T. Jensen, J. Selb, D. A. Boas, and M. Ashina, “Changes in cerebral blood flow after acetazolamide: an experimental study comparing near-infrared spectroscopy and SPECT,” Eur. J. Neurol. 16(4), 461–467 (2009).
[CrossRef] [PubMed]

D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003).
[CrossRef] [PubMed]

G. Strangman, M. A. Franceschini, and D. A. Boas, “Factors affecting the accuracy of near-infrared spectroscopy concentration calculations for focal changes in oxygenation parameters,” Neuroimage 18(4), 865–879 (2003).
[CrossRef] [PubMed]

D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and imaging with diffusing temporal field correlations,” Phys. Rev. Lett. 75(9), 1855–1858 (1995).
[CrossRef] [PubMed]

Brawanski, A.

M. Holzschuh, C. Woertgen, C. Metz, and A. Brawanski, “Comparison of changes in cerebral blood flow and cerebral oxygen saturation measured by near infrared spectroscopy (NIRS) after acetazolamide,” Acta Neurochir. (Wien) 139(1), 58–62 (1997).
[CrossRef] [PubMed]

Buck, A.

B. Weber, G. Westera, V. Treyer, C. Burger, N. Khan, and A. Buck, “Constant-infusion H(2)15O PET and acetazolamide challenge in the assessment of cerebral perfusion status,” J. Nucl. Med. 45(8), 1344–1350 (2004).
[PubMed]

Buckley, E. M.

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

Burdette, J. H.

Y. F. Yen, A. S. Field, E. M. Martin, N. Ari, J. H. Burdette, D. M. Moody, and A. M. Takahashi, “Test-retest reproducibility of quantitative CBF measurements using FAIR perfusion MRI and acetazolamide challenge,” Magn. Reson. Med. 47(5), 921–928 (2002).
[CrossRef] [PubMed]

Burger, C.

B. Weber, G. Westera, V. Treyer, C. Burger, N. Khan, and A. Buck, “Constant-infusion H(2)15O PET and acetazolamide challenge in the assessment of cerebral perfusion status,” J. Nucl. Med. 45(8), 1344–1350 (2004).
[PubMed]

Burnett, M. G.

Burns, R. A.

D. L. Ehrenreich, R. A. Burns, R. W. Alman, and J. F. Fazekas, “Influence of acetazolamide on cerebral blood flow,” Arch. Neurol. 5, 227–232 (1961).
[PubMed]

Buss, E.

B. M. Eicke, E. Buss, R. R. Bähr, G. Hajak, and W. Paulus, “Influence of acetazolamide and CO2 on extracranial flow volume and intracranial blood flow velocity,” Stroke 30(1), 76–80 (1999).
[PubMed]

Caltagirone, C.

M. Matteis, E. Troisi, B. C. Monaldo, C. Caltagirone, and M. Silvestrini, “Age and sex differences in cerebral hemodynamics: a transcranial Doppler study,” Stroke 29(5), 963–967 (1998).
[PubMed]

Campbell, L. E.

D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and imaging with diffusing temporal field correlations,” Phys. Rev. Lett. 75(9), 1855–1858 (1995).
[CrossRef] [PubMed]

Carney, A. L.

A. L. Carney and E. M. Anderson, “The system approach to brain blood flow,” Adv. Neurol. 30, 1–30 (1981).
[PubMed]

Carp, S.

Carp, S. A.

N. Roche-Labarbe, S. A. Carp, A. Surova, M. Patel, D. A. Boas, P. E. Grant, and M. A. Franceschini, “Noninvasive optical measures of CBV, StO(2), CBF index, and rCMRO(2) in human premature neonates’ brains in the first six weeks of life,” Hum. Brain Mapp. 31(3), 341–352 (2010).
[PubMed]

Celsis, P.

U. Sabatini, P. Celsis, G. Viallard, A. Rascol, and J. P. Marc-Vergnes, “Quantitative assessment of cerebral blood volume by single-photon emission computed tomography,” Stroke 22(3), 324–330 (1991).
[PubMed]

Chance, B.

A. Villringer and B. Chance, “Non-invasive optical spectroscopy and imaging of human brain function,” Trends Neurosci. 20(10), 435–442 (1997).
[CrossRef] [PubMed]

Chandar, K.

R. Roski, R. F. Spetzler, M. Owen, K. Chandar, J. G. Sholl, and F. E. Nulsen, “Reversal of seven-year old visual field defect with extracranial-intracranial arterial anastomosis,” Surg. Neurol. 10(4), 267–268 (1978).
[PubMed]

Cheung, C.

J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003).
[CrossRef] [PubMed]

Chimowitz, M. I.

M. I. Chimowitz, A. J. Furlan, S. C. Jones, C. A. Sila, R. L. Lorig, L. Paranandi, and G. J. Beck, “Transcranial Doppler assessment of cerebral perfusion reserve in patients with carotid occlusive disease and no evidence of cerebral infarction,” Neurology 43(2), 353–357 (1993).
[PubMed]

Choe, R.

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

T. Durduran, R. Choe, W. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010).
[CrossRef]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, “Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients,” Opt. Express 17(5), 3884–3902 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

Clemence, M.

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304 (1995).
[CrossRef] [PubMed]

Cook, N. M.

Cope, M.

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304 (1995).
[CrossRef] [PubMed]

S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys. Med. Biol. 37(7), 1531–1560 (1992).
[CrossRef] [PubMed]

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Roth, E. O. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult head, calf and forearm and the head of the newborn infant as a function of inter optode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[PubMed]

Cote, R.

R. Cote, H. J. Barnett, and D. W. Taylor, “Internal carotid occlusion: a prospective study,” Stroke 14(6), 898–902 (1983).
[PubMed]

Crelier, G. R.

R. D. Hoge, J. Atkinson, B. Gill, G. R. Crelier, S. Marrett, and G. B. Pike, “Linear coupling between cerebral blood flow and oxygen consumption in activated human cortex,” Proc. Natl. Acad. Sci. U.S.A. 96(16), 9403–9408 (1999).
[CrossRef] [PubMed]

Csiba, L.

G. Settakis, C. Molnár, L. Kerényi, J. Kollár, D. Legemate, L. Csiba, and B. Fülesdi, “Acetazolamide as a vasodilatory stimulus in cerebrovascular diseases and in conditions affecting the cerebral vasculature,” Eur. J. Neurol. 10(6), 609–620 (2003).
[CrossRef] [PubMed]

B. Fülesdi, M. Limburg, L. Oláh, D. Bereczki, L. Csiba, and J. Kollár, “Lack of gender difference in acetazolamide-induced cerebral vasomotor reactivity in patients suffering from type-1 diabetes mellitus,” Acta Diabetol. 38(3), 107–112 (2001).
[CrossRef] [PubMed]

Cubeddu, R.

A. Torricelli, A. Pifferi, P. Taroni, E. Giambattistelli, and R. Cubeddu, “In vivo optical characterization of human tissues from 610 to 1010 nm by time-resolved reflectance spectroscopy,” Phys. Med. Biol. 46(8), 2227–2237 (2001).
[CrossRef] [PubMed]

Cucchiara, B. L.

Culver, J. P.

J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003).
[CrossRef] [PubMed]

D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003).
[CrossRef] [PubMed]

D’Amico, E.

Dahl, A.

A. Dahl, D. Russell, R. Nyberg-Hansen, K. Rootwelt, and P. Mowinckel, “Simultaneous assessment of vasoreactivity using transcranial Doppler ultrasound and cerebral blood flow in healthy subjects,” J. Cereb. Blood Flow Metab. 14(6), 974–981 (1994).
[PubMed]

A. Dahl, K. F. Lindegaard, D. Russell, R. Nyberg-Hansen, K. Rootwelt, W. Sorteberg, and H. Nornes, “A comparison of transcranial Doppler and cerebral blood flow studies to assess cerebral vasoreactivity,” Stroke 23(1), 15–19 (1992).
[PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, R. Nyberg-Hansen, D. Russell, and H. Nornes, “Effect of acetazolamide on cerebral artery blood velocity and regional cerebral blood flow in normal subjects,” Acta Neurochir. (Wien) 97(3-4), 139–145 (1989).
[CrossRef] [PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, D. Russell, R. Nyberg-Hansen, and H. Nornes, “Blood velocity and regional blood flow in defined cerebral artery systems,” Acta Neurochir. (Wien) 97(1-2), 47–52 (1989).
[CrossRef] [PubMed]

Dai, G.

Davis, T. L.

T. L. Davis, K. K. Kwong, R. M. Weisskoff, and B. R. Rosen, “Calibrated functional MRI: mapping the dynamics of oxidative metabolism,” Proc. Natl. Acad. Sci. U.S.A. 95(4), 1834–1839 (1998).
[CrossRef] [PubMed]

Delpy, D. T.

I. Tachtsidis, M. Tisdall, D. T. Delpy, M. Smith, and C. E. Elwell, “Measurement of cerebral tissue oxygenation in young healthy volunteers during acetazolamide provocation: a transcranial Doppler and near-infrared spectroscopy investigation,” Adv. Exp. Med. Biol. 614, 389–396 (2008).
[CrossRef] [PubMed]

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304 (1995).
[CrossRef] [PubMed]

S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys. Med. Biol. 37(7), 1531–1560 (1992).
[CrossRef] [PubMed]

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Roth, E. O. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult head, calf and forearm and the head of the newborn infant as a function of inter optode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[PubMed]

Démolis, P.

P. Démolis, G. Florence, L. Thomas, Y. R. Tran Dinh, J. F. Giudicelli, J. Seylaz, and N. J. Alkayed, “Is the acetazolamide test valid for quantitative assessment of maximal cerebral autoregulatory vasodilation? An experimental study,” Stroke 31(2), 508–515 (2000).
[PubMed]

Desjardins, M.

Detre, J. A.

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, “Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients,” Opt. Express 17(5), 3884–3902 (2009).
[CrossRef] [PubMed]

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse optical measurement of blood flow, blood oxygenation, and metabolism in a human brain during sensorimotor cortex activation,” Opt. Lett. 29(15), 1766–1768 (2004).
[CrossRef] [PubMed]

J. A. Detre, O. B. Samuels, D. C. Alsop, J. B. Gonzalez-At, S. E. Kasner, and E. C. Raps, “Noninvasive magnetic resonance imaging evaluation of cerebral blood flow with acetazolamide challenge in patients with cerebrovascular stenosis,” J. Magn. Reson. Imaging 10(5), 870–875 (1999).
[CrossRef] [PubMed]

Dietsche, G.

J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J. Biomed. Opt. 10(4), 044002 (2005).
[CrossRef] [PubMed]

Duncan, A.

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304 (1995).
[CrossRef] [PubMed]

Durduran, T.

T. Durduran, R. Choe, W. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010).
[CrossRef]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, “Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients,” Opt. Express 17(5), 3884–3902 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse optical measurement of blood flow, blood oxygenation, and metabolism in a human brain during sensorimotor cortex activation,” Opt. Lett. 29(15), 1766–1768 (2004).
[CrossRef] [PubMed]

J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003).
[CrossRef] [PubMed]

Durham, S.

S. Durham, H. Smith, M. Rutigliano, and H. Yonas, “Assessment of cerebral vasoreactivity and stroke risk using Xe-CT acetazolamide challenge,” Stroke 22, 138 (1991).

Durning, S. M.

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

Dyken, M. L.

M. L. Dyken, E. Klatte, O. J. Kolar, and C. Surgeon, “Complete occlusion of common or internal carotid arteries. Clinical significance,” Arch. Neurol. 30(5), 343–346 (1974).
[PubMed]

Edlow, B. L.

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, “Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients,” Opt. Express 17(5), 3884–3902 (2009).
[CrossRef] [PubMed]

Edwards, A. D.

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Roth, E. O. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult head, calf and forearm and the head of the newborn infant as a function of inter optode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[PubMed]

Ehrenreich, D. L.

D. L. Ehrenreich, R. A. Burns, R. W. Alman, and J. F. Fazekas, “Influence of acetazolamide on cerebral blood flow,” Arch. Neurol. 5, 227–232 (1961).
[PubMed]

Eichling, J. O.

R. L. Grubb, M. E. Raichle, J. O. Eichling, and M. M. Ter-Pogossian, “The effects of changes in PaCO2 on cerebral blood volume, blood flow, and vascular mean transit time,” Stroke 5(5), 630–639 (1974).
[PubMed]

Eicke, B. M.

B. M. Eicke, E. Buss, R. R. Bähr, G. Hajak, and W. Paulus, “Influence of acetazolamide and CO2 on extracranial flow volume and intracranial blood flow velocity,” Stroke 30(1), 76–80 (1999).
[PubMed]

Einhäupl, K.

T. Kreisig, P. Schmiedek, G. Leinsinger, K. Einhäupl, and E. Moser, “[133Xe-DSPECT: normal values of resting cerebral blood flow and reserve capacity],” Nucl. Med. (Stuttg.) 26(5), 192–197 (1987).
[PubMed]

Einhäupl, K. M.

A. Piepgras, P. Schmiedek, G. Leinsinger, R. L. Haberl, C. M. Kirsch, and K. M. Einhäupl, “A simple test to assess cerebrovascular reserve capacity using transcranial Doppler sonography and acetazolamide,” Stroke 21(9), 1306–1311 (1990).
[PubMed]

Elbert, T.

J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J. Biomed. Opt. 10(4), 044002 (2005).
[CrossRef] [PubMed]

Elwell, C. E.

T. S. Leung, I. Tachtsidis, M. M. Tisdall, C. Pritchard, M. Smith, and C. E. Elwell, “Estimating a modified Grubb’s exponent in healthy human brains with near infrared spectroscopy and transcranial Doppler,” Physiol. Meas. 30(1), 1–12 (2009).
[CrossRef] [PubMed]

I. Tachtsidis, M. Tisdall, D. T. Delpy, M. Smith, and C. E. Elwell, “Measurement of cerebral tissue oxygenation in young healthy volunteers during acetazolamide provocation: a transcranial Doppler and near-infrared spectroscopy investigation,” Adv. Exp. Med. Biol. 614, 389–396 (2008).
[CrossRef] [PubMed]

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304 (1995).
[CrossRef] [PubMed]

Enblad, P.

P. Frykholm, J. L. R. Andersson, J. Valtysson, H. C. Silander, L. Hillered, L. Persson, Y. Olsson, W. R. Yu, G. Westerberg, Y. Watanabe, B. Långström, and P. Enblad, “A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion-reperfusion primate model,” Acta Neurol. Scand. 102(1), 18–26 (2000).
[CrossRef] [PubMed]

Essenpreis, M.

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Roth, E. O. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult head, calf and forearm and the head of the newborn infant as a function of inter optode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[PubMed]

Fazekas, J. F.

D. L. Ehrenreich, R. A. Burns, R. W. Alman, and J. F. Fazekas, “Influence of acetazolamide on cerebral blood flow,” Arch. Neurol. 5, 227–232 (1961).
[PubMed]

Field, A. S.

Y. F. Yen, A. S. Field, E. M. Martin, N. Ari, J. H. Burdette, D. M. Moody, and A. M. Takahashi, “Test-retest reproducibility of quantitative CBF measurements using FAIR perfusion MRI and acetazolamide challenge,” Magn. Reson. Med. 47(5), 921–928 (2002).
[CrossRef] [PubMed]

Florence, G.

P. Démolis, G. Florence, L. Thomas, Y. R. Tran Dinh, J. F. Giudicelli, J. Seylaz, and N. J. Alkayed, “Is the acetazolamide test valid for quantitative assessment of maximal cerebral autoregulatory vasodilation? An experimental study,” Stroke 31(2), 508–515 (2000).
[PubMed]

Fog, M.

M. Fog, “Cerebral circulation: the reaction of the pial arteries to a fall in blood pressure,” Arch. Neurol. Psychiatry 37, 351 (1937).

Franceschini, M.

Franceschini, M. A.

N. Roche-Labarbe, S. A. Carp, A. Surova, M. Patel, D. A. Boas, P. E. Grant, and M. A. Franceschini, “Noninvasive optical measures of CBV, StO(2), CBF index, and rCMRO(2) in human premature neonates’ brains in the first six weeks of life,” Hum. Brain Mapp. 31(3), 341–352 (2010).
[PubMed]

G. Strangman, M. A. Franceschini, and D. A. Boas, “Factors affecting the accuracy of near-infrared spectroscopy concentration calculations for focal changes in oxygenation parameters,” Neuroimage 18(4), 865–879 (2003).
[CrossRef] [PubMed]

Frangos, S.

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

Frykholm, P.

P. Frykholm, J. L. R. Andersson, J. Valtysson, H. C. Silander, L. Hillered, L. Persson, Y. Olsson, W. R. Yu, G. Westerberg, Y. Watanabe, B. Långström, and P. Enblad, “A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion-reperfusion primate model,” Acta Neurol. Scand. 102(1), 18–26 (2000).
[CrossRef] [PubMed]

Fülesdi, B.

G. Settakis, C. Molnár, L. Kerényi, J. Kollár, D. Legemate, L. Csiba, and B. Fülesdi, “Acetazolamide as a vasodilatory stimulus in cerebrovascular diseases and in conditions affecting the cerebral vasculature,” Eur. J. Neurol. 10(6), 609–620 (2003).
[CrossRef] [PubMed]

B. Fülesdi, M. Limburg, L. Oláh, D. Bereczki, L. Csiba, and J. Kollár, “Lack of gender difference in acetazolamide-induced cerebral vasomotor reactivity in patients suffering from type-1 diabetes mellitus,” Acta Diabetol. 38(3), 107–112 (2001).
[CrossRef] [PubMed]

Furlan, A. J.

M. I. Chimowitz, A. J. Furlan, S. C. Jones, C. A. Sila, R. L. Lorig, L. Paranandi, and G. J. Beck, “Transcranial Doppler assessment of cerebral perfusion reserve in patients with carotid occlusive disease and no evidence of cerebral infarction,” Neurology 43(2), 353–357 (1993).
[PubMed]

Furuya, D.

J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003).
[CrossRef] [PubMed]

Gagnon, L.

Gaynor, J. W.

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

Gertsch, S.

B. P. Wagner, S. Gertsch, R. A. Ammann, and J. Pfenninger, “Reproducibility of the blood flow index as noninvasive, bedside estimation of cerebral blood flow,” Intensive Care Med. 29(2), 196–200 (2003).
[PubMed]

Giambattistelli, E.

A. Torricelli, A. Pifferi, P. Taroni, E. Giambattistelli, and R. Cubeddu, “In vivo optical characterization of human tissues from 610 to 1010 nm by time-resolved reflectance spectroscopy,” Phys. Med. Biol. 46(8), 2227–2237 (2001).
[CrossRef] [PubMed]

Gill, B.

R. D. Hoge, J. Atkinson, B. Gill, G. R. Crelier, S. Marrett, and G. B. Pike, “Linear coupling between cerebral blood flow and oxygen consumption in activated human cortex,” Proc. Natl. Acad. Sci. U.S.A. 96(16), 9403–9408 (1999).
[CrossRef] [PubMed]

Gisler, T.

J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J. Biomed. Opt. 10(4), 044002 (2005).
[CrossRef] [PubMed]

Giudicelli, J. F.

P. Démolis, G. Florence, L. Thomas, Y. R. Tran Dinh, J. F. Giudicelli, J. Seylaz, and N. J. Alkayed, “Is the acetazolamide test valid for quantitative assessment of maximal cerebral autoregulatory vasodilation? An experimental study,” Stroke 31(2), 508–515 (2000).
[PubMed]

Gonzalez-At, J. B.

J. A. Detre, O. B. Samuels, D. C. Alsop, J. B. Gonzalez-At, S. E. Kasner, and E. C. Raps, “Noninvasive magnetic resonance imaging evaluation of cerebral blood flow with acetazolamide challenge in patients with cerebrovascular stenosis,” J. Magn. Reson. Imaging 10(5), 870–875 (1999).
[CrossRef] [PubMed]

Grady, M. S.

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

Grant, P. E.

N. Roche-Labarbe, S. A. Carp, A. Surova, M. Patel, D. A. Boas, P. E. Grant, and M. A. Franceschini, “Noninvasive optical measures of CBV, StO(2), CBF index, and rCMRO(2) in human premature neonates’ brains in the first six weeks of life,” Hum. Brain Mapp. 31(3), 341–352 (2010).
[PubMed]

Gratton, E.

Grebe, R.

N. Roche-Labarbe, F. Wallois, E. Ponchel, G. Kongolo, and R. Grebe, “Coupled oxygenation oscillation measured by NIRS and intermittent cerebral activation on EEG in premature infants,” Neuroimage 36(3), 718–727 (2007).
[CrossRef] [PubMed]

Greenberg, J. H.

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, “Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients,” Opt. Express 17(5), 3884–3902 (2009).
[CrossRef] [PubMed]

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse optical measurement of blood flow, blood oxygenation, and metabolism in a human brain during sensorimotor cortex activation,” Opt. Lett. 29(15), 1766–1768 (2004).
[CrossRef] [PubMed]

J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003).
[CrossRef] [PubMed]

Grubb, R. L.

W. J. Powers, L. W. Tempel, and R. L. Grubb., “Influence of cerebral hemodynamics on stroke risk: one-year follow-up of 30 medically treated patients,” Ann. Neurol. 25(4), 325–330 (1989).
[CrossRef] [PubMed]

R. L. Grubb, M. E. Raichle, J. O. Eichling, and M. M. Ter-Pogossian, “The effects of changes in PaCO2 on cerebral blood volume, blood flow, and vascular mean transit time,” Stroke 5(5), 630–639 (1974).
[PubMed]

Haberl, R. L.

A. Piepgras, P. Schmiedek, G. Leinsinger, R. L. Haberl, C. M. Kirsch, and K. M. Einhäupl, “A simple test to assess cerebrovascular reserve capacity using transcranial Doppler sonography and acetazolamide,” Stroke 21(9), 1306–1311 (1990).
[PubMed]

Hajak, G.

B. M. Eicke, E. Buss, R. R. Bähr, G. Hajak, and W. Paulus, “Influence of acetazolamide and CO2 on extracranial flow volume and intracranial blood flow velocity,” Stroke 30(1), 76–80 (1999).
[PubMed]

Hamamoto, H.

H. Yamaguchi, H. Yamauchi, S. Hazama, H. Hamamoto, and N. Inoue, “Correlation between cerebral oxygen metabolism and cerebral blood flow simultaneously measured before and after acetazolamide administration,” J. Biomed. Opt. 4(4), 418 (1999).
[CrossRef]

Hazama, S.

H. Yamaguchi, H. Yamauchi, S. Hazama, H. Hamamoto, and N. Inoue, “Correlation between cerebral oxygen metabolism and cerebral blood flow simultaneously measured before and after acetazolamide administration,” J. Biomed. Opt. 4(4), 418 (1999).
[CrossRef]

Henriksen, L.

S. Vorstrup, L. Henriksen, and O. B. Paulson, “Effect of acetazolamide on cerebral blood flow and cerebral metabolic rate for oxygen,” J. Clin. Invest. 74(5), 1634–1639 (1984).
[CrossRef] [PubMed]

Hillered, L.

P. Frykholm, J. L. R. Andersson, J. Valtysson, H. C. Silander, L. Hillered, L. Persson, Y. Olsson, W. R. Yu, G. Westerberg, Y. Watanabe, B. Långström, and P. Enblad, “A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion-reperfusion primate model,” Acta Neurol. Scand. 102(1), 18–26 (2000).
[CrossRef] [PubMed]

Hillman, E. M.

E. M. Hillman, “Optical brain imaging in vivo: techniques and applications from animal to man,” J. Biomed. Opt. 12(5), 051402 (2007).
[CrossRef] [PubMed]

Hoge, R. D.

D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003).
[CrossRef] [PubMed]

R. D. Hoge, J. Atkinson, B. Gill, G. R. Crelier, S. Marrett, and G. B. Pike, “Linear coupling between cerebral blood flow and oxygen consumption in activated human cortex,” Proc. Natl. Acad. Sci. U.S.A. 96(16), 9403–9408 (1999).
[CrossRef] [PubMed]

Holzschuh, M.

M. Holzschuh, C. Woertgen, C. Metz, and A. Brawanski, “Comparison of changes in cerebral blood flow and cerebral oxygen saturation measured by near infrared spectroscopy (NIRS) after acetazolamide,” Acta Neurochir. (Wien) 139(1), 58–62 (1997).
[CrossRef] [PubMed]

Hoshi, Y.

S. Kohri, Y. Hoshi, M. Tamura, C. Kato, Y. Kuge, and N. Tamaki, “Quantitative evaluation of the relative contribution ratio of cerebral tissue to near-infrared signals in the adult human head: a preliminary study,” Physiol. Meas. 23(2), 301–312 (2002).
[CrossRef] [PubMed]

Hueber, D.

Hurt, H. H.

Ichikura, A.

M. Kaminogo, A. Ichikura, S. Shibata, T. Toba, and M. Yonekura, “Effect of acetazolamide on regional cerebral oxygen saturation and regional cerebral blood flow,” Stroke 26(12), 2358–2360 (1995).
[PubMed]

Iftime, D.

J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J. Biomed. Opt. 10(4), 044002 (2005).
[CrossRef] [PubMed]

Inoue, N.

H. Yamaguchi, H. Yamauchi, S. Hazama, H. Hamamoto, and N. Inoue, “Correlation between cerebral oxygen metabolism and cerebral blood flow simultaneously measured before and after acetazolamide administration,” J. Biomed. Opt. 4(4), 418 (1999).
[CrossRef]

Jasdzewski, G.

D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003).
[CrossRef] [PubMed]

Jehanne-Lacasse, J.

Jensen, L. T.

H. W. Schytz, T. Wienecke, L. T. Jensen, J. Selb, D. A. Boas, and M. Ashina, “Changes in cerebral blood flow after acetazolamide: an experimental study comparing near-infrared spectroscopy and SPECT,” Eur. J. Neurol. 16(4), 461–467 (2009).
[CrossRef] [PubMed]

Johnston, D.

J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001).
[CrossRef] [PubMed]

Jones, M.

J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001).
[CrossRef] [PubMed]

Jones, S. C.

M. I. Chimowitz, A. J. Furlan, S. C. Jones, C. A. Sila, R. L. Lorig, L. Paranandi, and G. J. Beck, “Transcranial Doppler assessment of cerebral perfusion reserve in patients with carotid occlusive disease and no evidence of cerebral infarction,” Neurology 43(2), 353–357 (1993).
[PubMed]

Kaminogo, M.

M. Kaminogo, A. Ichikura, S. Shibata, T. Toba, and M. Yonekura, “Effect of acetazolamide on regional cerebral oxygen saturation and regional cerebral blood flow,” Stroke 26(12), 2358–2360 (1995).
[PubMed]

Kasner, S. E.

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, “Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients,” Opt. Express 17(5), 3884–3902 (2009).
[CrossRef] [PubMed]

J. A. Detre, O. B. Samuels, D. C. Alsop, J. B. Gonzalez-At, S. E. Kasner, and E. C. Raps, “Noninvasive magnetic resonance imaging evaluation of cerebral blood flow with acetazolamide challenge in patients with cerebrovascular stenosis,” J. Magn. Reson. Imaging 10(5), 870–875 (1999).
[CrossRef] [PubMed]

Kato, C.

S. Kohri, Y. Hoshi, M. Tamura, C. Kato, Y. Kuge, and N. Tamaki, “Quantitative evaluation of the relative contribution ratio of cerebral tissue to near-infrared signals in the adult human head: a preliminary study,” Physiol. Meas. 23(2), 301–312 (2002).
[CrossRef] [PubMed]

Keller, E.

E. Keller, M. Wolf, M. Martin, and Y. Yonekawa, “Estimation of cerebral oxygenation and hemodynamics in cerebral vasospasm using indocyaningreen dye dilution and near infrared spectroscopy: a case report,” J. Neurosurg. Anesthesiol. 13(1), 43–48 (2001).
[CrossRef] [PubMed]

Kempski, O. S.

P. T. Ulrich, T. Becker, and O. S. Kempski, “Correlation of cerebral blood flow and MCA flow velocity measured in healthy volunteers during acetazolamide and CO2 stimulation,” J. Neurol. Sci. 129(2), 120–130 (1995).
[CrossRef] [PubMed]

Kerényi, L.

G. Settakis, C. Molnár, L. Kerényi, J. Kollár, D. Legemate, L. Csiba, and B. Fülesdi, “Acetazolamide as a vasodilatory stimulus in cerebrovascular diseases and in conditions affecting the cerebral vasculature,” Eur. J. Neurol. 10(6), 609–620 (2003).
[CrossRef] [PubMed]

Khan, N.

B. Weber, G. Westera, V. Treyer, C. Burger, N. Khan, and A. Buck, “Constant-infusion H(2)15O PET and acetazolamide challenge in the assessment of cerebral perfusion status,” J. Nucl. Med. 45(8), 1344–1350 (2004).
[PubMed]

Kim, M. N.

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, “Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients,” Opt. Express 17(5), 3884–3902 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

Kim, S. G.

S. G. Kim, E. Rostrup, H. B. Larsson, S. Ogawa, and O. B. Paulson, “Determination of relative CMRO2 from CBF and BOLD changes: significant increase of oxygen consumption rate during visual stimulation,” Magn. Reson. Med. 41(6), 1152–1161 (1999).
[CrossRef] [PubMed]

Kim, Y.

Kirsch, C. M.

A. Piepgras, P. Schmiedek, G. Leinsinger, R. L. Haberl, C. M. Kirsch, and K. M. Einhäupl, “A simple test to assess cerebrovascular reserve capacity using transcranial Doppler sonography and acetazolamide,” Stroke 21(9), 1306–1311 (1990).
[PubMed]

Klatte, E.

M. L. Dyken, E. Klatte, O. J. Kolar, and C. Surgeon, “Complete occlusion of common or internal carotid arteries. Clinical significance,” Arch. Neurol. 30(5), 343–346 (1974).
[PubMed]

Kleiser, B.

B. Widder, B. Kleiser, and H. Krapf, “Course of cerebrovascular reactivity in patients with carotid artery occlusions,” Stroke 25(10), 1963–1967 (1994).
[PubMed]

B. Kleiser and B. Widder, “Course of carotid artery occlusions with impaired cerebrovascular reactivity,” Stroke 23(2), 171–174 (1992).
[PubMed]

Kofke, W. A.

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

Kohri, S.

S. Kohri, Y. Hoshi, M. Tamura, C. Kato, Y. Kuge, and N. Tamaki, “Quantitative evaluation of the relative contribution ratio of cerebral tissue to near-infrared signals in the adult human head: a preliminary study,” Physiol. Meas. 23(2), 301–312 (2002).
[CrossRef] [PubMed]

Kolar, O. J.

M. L. Dyken, E. Klatte, O. J. Kolar, and C. Surgeon, “Complete occlusion of common or internal carotid arteries. Clinical significance,” Arch. Neurol. 30(5), 343–346 (1974).
[PubMed]

Kollár, J.

G. Settakis, C. Molnár, L. Kerényi, J. Kollár, D. Legemate, L. Csiba, and B. Fülesdi, “Acetazolamide as a vasodilatory stimulus in cerebrovascular diseases and in conditions affecting the cerebral vasculature,” Eur. J. Neurol. 10(6), 609–620 (2003).
[CrossRef] [PubMed]

B. Fülesdi, M. Limburg, L. Oláh, D. Bereczki, L. Csiba, and J. Kollár, “Lack of gender difference in acetazolamide-induced cerebral vasomotor reactivity in patients suffering from type-1 diabetes mellitus,” Acta Diabetol. 38(3), 107–112 (2001).
[CrossRef] [PubMed]

Kongolo, G.

N. Roche-Labarbe, F. Wallois, E. Ponchel, G. Kongolo, and R. Grebe, “Coupled oxygenation oscillation measured by NIRS and intermittent cerebral activation on EEG in premature infants,” Neuroimage 36(3), 718–727 (2007).
[CrossRef] [PubMed]

Kontos, H. A.

H. A. Kontos, “Validity of cerebral arterial blood flow calculations from velocity measurements,” Stroke 20(1), 1–3 (1989).
[PubMed]

Krapf, H.

B. Widder, B. Kleiser, and H. Krapf, “Course of cerebrovascular reactivity in patients with carotid artery occlusions,” Stroke 25(10), 1963–1967 (1994).
[PubMed]

Kreisig, T.

T. Kreisig, P. Schmiedek, G. Leinsinger, K. Einhäupl, and E. Moser, “[133Xe-DSPECT: normal values of resting cerebral blood flow and reserve capacity],” Nucl. Med. (Stuttg.) 26(5), 192–197 (1987).
[PubMed]

Kuge, Y.

S. Kohri, Y. Hoshi, M. Tamura, C. Kato, Y. Kuge, and N. Tamaki, “Quantitative evaluation of the relative contribution ratio of cerebral tissue to near-infrared signals in the adult human head: a preliminary study,” Physiol. Meas. 23(2), 301–312 (2002).
[CrossRef] [PubMed]

Kwong, K. K.

T. L. Davis, K. K. Kwong, R. M. Weisskoff, and B. R. Rosen, “Calibrated functional MRI: mapping the dynamics of oxidative metabolism,” Proc. Natl. Acad. Sci. U.S.A. 95(4), 1834–1839 (1998).
[CrossRef] [PubMed]

Långström, B.

P. Frykholm, J. L. R. Andersson, J. Valtysson, H. C. Silander, L. Hillered, L. Persson, Y. Olsson, W. R. Yu, G. Westerberg, Y. Watanabe, B. Långström, and P. Enblad, “A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion-reperfusion primate model,” Acta Neurol. Scand. 102(1), 18–26 (2000).
[CrossRef] [PubMed]

Larsson, H. B.

S. G. Kim, E. Rostrup, H. B. Larsson, S. Ogawa, and O. B. Paulson, “Determination of relative CMRO2 from CBF and BOLD changes: significant increase of oxygen consumption rate during visual stimulation,” Magn. Reson. Med. 41(6), 1152–1161 (1999).
[CrossRef] [PubMed]

Lassen, N. A.

N. A. Lassen, “Cerebral blood flow and oxygen consumption in man,” Physiol. Rev. 39(2), 183–238 (1959).
[PubMed]

Laux, B. E.

B. E. Laux and M. E. Raichle, “The effect of acetazolamide on cerebral blood flow and oxygen utilization in the rhesus monkey,” J. Clin. Invest. 62(3), 585–592 (1978).
[CrossRef] [PubMed]

Legemate, D.

G. Settakis, C. Molnár, L. Kerényi, J. Kollár, D. Legemate, L. Csiba, and B. Fülesdi, “Acetazolamide as a vasodilatory stimulus in cerebrovascular diseases and in conditions affecting the cerebral vasculature,” Eur. J. Neurol. 10(6), 609–620 (2003).
[CrossRef] [PubMed]

Leinsinger, G.

A. Piepgras, P. Schmiedek, G. Leinsinger, R. L. Haberl, C. M. Kirsch, and K. M. Einhäupl, “A simple test to assess cerebrovascular reserve capacity using transcranial Doppler sonography and acetazolamide,” Stroke 21(9), 1306–1311 (1990).
[PubMed]

T. Kreisig, P. Schmiedek, G. Leinsinger, K. Einhäupl, and E. Moser, “[133Xe-DSPECT: normal values of resting cerebral blood flow and reserve capacity],” Nucl. Med. (Stuttg.) 26(5), 192–197 (1987).
[PubMed]

Lesage, F.

Leung, T. S.

T. S. Leung, I. Tachtsidis, M. M. Tisdall, C. Pritchard, M. Smith, and C. E. Elwell, “Estimating a modified Grubb’s exponent in healthy human brains with near infrared spectroscopy and transcranial Doppler,” Physiol. Meas. 30(1), 1–12 (2009).
[CrossRef] [PubMed]

Levine, J. M.

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

Li, J.

J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J. Biomed. Opt. 10(4), 044002 (2005).
[CrossRef] [PubMed]

Licht, D. J.

Limburg, M.

B. Fülesdi, M. Limburg, L. Oláh, D. Bereczki, L. Csiba, and J. Kollár, “Lack of gender difference in acetazolamide-induced cerebral vasomotor reactivity in patients suffering from type-1 diabetes mellitus,” Acta Diabetol. 38(3), 107–112 (2001).
[CrossRef] [PubMed]

Lindegaard, K. F.

A. Dahl, K. F. Lindegaard, D. Russell, R. Nyberg-Hansen, K. Rootwelt, W. Sorteberg, and H. Nornes, “A comparison of transcranial Doppler and cerebral blood flow studies to assess cerebral vasoreactivity,” Stroke 23(1), 15–19 (1992).
[PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, R. Nyberg-Hansen, D. Russell, and H. Nornes, “Effect of acetazolamide on cerebral artery blood velocity and regional cerebral blood flow in normal subjects,” Acta Neurochir. (Wien) 97(3-4), 139–145 (1989).
[CrossRef] [PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, D. Russell, R. Nyberg-Hansen, and H. Nornes, “Blood velocity and regional blood flow in defined cerebral artery systems,” Acta Neurochir. (Wien) 97(1-2), 47–52 (1989).
[CrossRef] [PubMed]

Lorig, R. L.

M. I. Chimowitz, A. J. Furlan, S. C. Jones, C. A. Sila, R. L. Lorig, L. Paranandi, and G. J. Beck, “Transcranial Doppler assessment of cerebral perfusion reserve in patients with carotid occlusive disease and no evidence of cerebral infarction,” Neurology 43(2), 353–357 (1993).
[PubMed]

Maloney-Wilensky, E.

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

Mandeville, J. B.

D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003).
[CrossRef] [PubMed]

Marc-Vergnes, J. P.

U. Sabatini, P. Celsis, G. Viallard, A. Rascol, and J. P. Marc-Vergnes, “Quantitative assessment of cerebral blood volume by single-photon emission computed tomography,” Stroke 22(3), 324–330 (1991).
[PubMed]

Maret, G.

J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J. Biomed. Opt. 10(4), 044002 (2005).
[CrossRef] [PubMed]

Marrett, S.

R. D. Hoge, J. Atkinson, B. Gill, G. R. Crelier, S. Marrett, and G. B. Pike, “Linear coupling between cerebral blood flow and oxygen consumption in activated human cortex,” Proc. Natl. Acad. Sci. U.S.A. 96(16), 9403–9408 (1999).
[CrossRef] [PubMed]

Martin, E. M.

Y. F. Yen, A. S. Field, E. M. Martin, N. Ari, J. H. Burdette, D. M. Moody, and A. M. Takahashi, “Test-retest reproducibility of quantitative CBF measurements using FAIR perfusion MRI and acetazolamide challenge,” Magn. Reson. Med. 47(5), 921–928 (2002).
[CrossRef] [PubMed]

Martin, M.

E. Keller, M. Wolf, M. Martin, and Y. Yonekawa, “Estimation of cerebral oxygenation and hemodynamics in cerebral vasospasm using indocyaningreen dye dilution and near infrared spectroscopy: a case report,” J. Neurosurg. Anesthesiol. 13(1), 43–48 (2001).
[CrossRef] [PubMed]

Martindale, J.

J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001).
[CrossRef] [PubMed]

Mason, S. E.

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

Matteis, M.

M. Matteis, E. Troisi, B. C. Monaldo, C. Caltagirone, and M. Silvestrini, “Age and sex differences in cerebral hemodynamics: a transcranial Doppler study,” Stroke 29(5), 963–967 (1998).
[PubMed]

Mayhew, J.

J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001).
[CrossRef] [PubMed]

McCormick, D. C.

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Roth, E. O. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult head, calf and forearm and the head of the newborn infant as a function of inter optode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[PubMed]

Mchedlishvili, G. I.

G. I. Mchedlishvili, N. P. Mitagvaria, and L. G. Ormotsadze, “Vascular mechanisms controlling a constant blood supply to the brain (“autoregulation”),” Stroke 4(5), 742–750 (1973).
[PubMed]

Meek, J. H.

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304 (1995).
[CrossRef] [PubMed]

Metz, C.

M. Holzschuh, C. Woertgen, C. Metz, and A. Brawanski, “Comparison of changes in cerebral blood flow and cerebral oxygen saturation measured by near infrared spectroscopy (NIRS) after acetazolamide,” Acta Neurochir. (Wien) 139(1), 58–62 (1997).
[CrossRef] [PubMed]

Mitagvaria, N. P.

G. I. Mchedlishvili, N. P. Mitagvaria, and L. G. Ormotsadze, “Vascular mechanisms controlling a constant blood supply to the brain (“autoregulation”),” Stroke 4(5), 742–750 (1973).
[PubMed]

Molnár, C.

G. Settakis, C. Molnár, L. Kerényi, J. Kollár, D. Legemate, L. Csiba, and B. Fülesdi, “Acetazolamide as a vasodilatory stimulus in cerebrovascular diseases and in conditions affecting the cerebral vasculature,” Eur. J. Neurol. 10(6), 609–620 (2003).
[CrossRef] [PubMed]

Monaldo, B. C.

M. Matteis, E. Troisi, B. C. Monaldo, C. Caltagirone, and M. Silvestrini, “Age and sex differences in cerebral hemodynamics: a transcranial Doppler study,” Stroke 29(5), 963–967 (1998).
[PubMed]

Montenegro, L. M.

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

Moody, D. M.

Y. F. Yen, A. S. Field, E. M. Martin, N. Ari, J. H. Burdette, D. M. Moody, and A. M. Takahashi, “Test-retest reproducibility of quantitative CBF measurements using FAIR perfusion MRI and acetazolamide challenge,” Magn. Reson. Med. 47(5), 921–928 (2002).
[CrossRef] [PubMed]

Moser, E.

T. Kreisig, P. Schmiedek, G. Leinsinger, K. Einhäupl, and E. Moser, “[133Xe-DSPECT: normal values of resting cerebral blood flow and reserve capacity],” Nucl. Med. (Stuttg.) 26(5), 192–197 (1987).
[PubMed]

Moss, H. E.

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

Mowinckel, P.

A. Dahl, D. Russell, R. Nyberg-Hansen, K. Rootwelt, and P. Mowinckel, “Simultaneous assessment of vasoreactivity using transcranial Doppler ultrasound and cerebral blood flow in healthy subjects,” J. Cereb. Blood Flow Metab. 14(6), 974–981 (1994).
[PubMed]

Nicolson, S. C.

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

Nornes, H.

A. Dahl, K. F. Lindegaard, D. Russell, R. Nyberg-Hansen, K. Rootwelt, W. Sorteberg, and H. Nornes, “A comparison of transcranial Doppler and cerebral blood flow studies to assess cerebral vasoreactivity,” Stroke 23(1), 15–19 (1992).
[PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, R. Nyberg-Hansen, D. Russell, and H. Nornes, “Effect of acetazolamide on cerebral artery blood velocity and regional cerebral blood flow in normal subjects,” Acta Neurochir. (Wien) 97(3-4), 139–145 (1989).
[CrossRef] [PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, D. Russell, R. Nyberg-Hansen, and H. Nornes, “Blood velocity and regional blood flow in defined cerebral artery systems,” Acta Neurochir. (Wien) 97(1-2), 47–52 (1989).
[CrossRef] [PubMed]

Nulsen, F. E.

R. Roski, R. F. Spetzler, M. Owen, K. Chandar, J. G. Sholl, and F. E. Nulsen, “Reversal of seven-year old visual field defect with extracranial-intracranial arterial anastomosis,” Surg. Neurol. 10(4), 267–268 (1978).
[PubMed]

Nyberg-Hansen, R.

A. Dahl, D. Russell, R. Nyberg-Hansen, K. Rootwelt, and P. Mowinckel, “Simultaneous assessment of vasoreactivity using transcranial Doppler ultrasound and cerebral blood flow in healthy subjects,” J. Cereb. Blood Flow Metab. 14(6), 974–981 (1994).
[PubMed]

A. Dahl, K. F. Lindegaard, D. Russell, R. Nyberg-Hansen, K. Rootwelt, W. Sorteberg, and H. Nornes, “A comparison of transcranial Doppler and cerebral blood flow studies to assess cerebral vasoreactivity,” Stroke 23(1), 15–19 (1992).
[PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, R. Nyberg-Hansen, D. Russell, and H. Nornes, “Effect of acetazolamide on cerebral artery blood velocity and regional cerebral blood flow in normal subjects,” Acta Neurochir. (Wien) 97(3-4), 139–145 (1989).
[CrossRef] [PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, D. Russell, R. Nyberg-Hansen, and H. Nornes, “Blood velocity and regional blood flow in defined cerebral artery systems,” Acta Neurochir. (Wien) 97(1-2), 47–52 (1989).
[CrossRef] [PubMed]

Ogawa, S.

S. G. Kim, E. Rostrup, H. B. Larsson, S. Ogawa, and O. B. Paulson, “Determination of relative CMRO2 from CBF and BOLD changes: significant increase of oxygen consumption rate during visual stimulation,” Magn. Reson. Med. 41(6), 1152–1161 (1999).
[CrossRef] [PubMed]

Oláh, L.

B. Fülesdi, M. Limburg, L. Oláh, D. Bereczki, L. Csiba, and J. Kollár, “Lack of gender difference in acetazolamide-induced cerebral vasomotor reactivity in patients suffering from type-1 diabetes mellitus,” Acta Diabetol. 38(3), 107–112 (2001).
[CrossRef] [PubMed]

Olsson, Y.

P. Frykholm, J. L. R. Andersson, J. Valtysson, H. C. Silander, L. Hillered, L. Persson, Y. Olsson, W. R. Yu, G. Westerberg, Y. Watanabe, B. Långström, and P. Enblad, “A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion-reperfusion primate model,” Acta Neurol. Scand. 102(1), 18–26 (2000).
[CrossRef] [PubMed]

Ormotsadze, L. G.

G. I. Mchedlishvili, N. P. Mitagvaria, and L. G. Ormotsadze, “Vascular mechanisms controlling a constant blood supply to the brain (“autoregulation”),” Stroke 4(5), 742–750 (1973).
[PubMed]

Owen, M.

R. Roski, R. F. Spetzler, M. Owen, K. Chandar, J. G. Sholl, and F. E. Nulsen, “Reversal of seven-year old visual field defect with extracranial-intracranial arterial anastomosis,” Surg. Neurol. 10(4), 267–268 (1978).
[PubMed]

Paranandi, L.

M. I. Chimowitz, A. J. Furlan, S. C. Jones, C. A. Sila, R. L. Lorig, L. Paranandi, and G. J. Beck, “Transcranial Doppler assessment of cerebral perfusion reserve in patients with carotid occlusive disease and no evidence of cerebral infarction,” Neurology 43(2), 353–357 (1993).
[PubMed]

Patel, M.

N. Roche-Labarbe, S. A. Carp, A. Surova, M. Patel, D. A. Boas, P. E. Grant, and M. A. Franceschini, “Noninvasive optical measures of CBV, StO(2), CBF index, and rCMRO(2) in human premature neonates’ brains in the first six weeks of life,” Hum. Brain Mapp. 31(3), 341–352 (2010).
[PubMed]

Paulson, O. B.

S. G. Kim, E. Rostrup, H. B. Larsson, S. Ogawa, and O. B. Paulson, “Determination of relative CMRO2 from CBF and BOLD changes: significant increase of oxygen consumption rate during visual stimulation,” Magn. Reson. Med. 41(6), 1152–1161 (1999).
[CrossRef] [PubMed]

S. Vorstrup, L. Henriksen, and O. B. Paulson, “Effect of acetazolamide on cerebral blood flow and cerebral metabolic rate for oxygen,” J. Clin. Invest. 74(5), 1634–1639 (1984).
[CrossRef] [PubMed]

Paulus, W.

B. M. Eicke, E. Buss, R. R. Bähr, G. Hajak, and W. Paulus, “Influence of acetazolamide and CO2 on extracranial flow volume and intracranial blood flow velocity,” Stroke 30(1), 76–80 (1999).
[PubMed]

Persson, L.

P. Frykholm, J. L. R. Andersson, J. Valtysson, H. C. Silander, L. Hillered, L. Persson, Y. Olsson, W. R. Yu, G. Westerberg, Y. Watanabe, B. Långström, and P. Enblad, “A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion-reperfusion primate model,” Acta Neurol. Scand. 102(1), 18–26 (2000).
[CrossRef] [PubMed]

Pfenninger, J.

B. P. Wagner, S. Gertsch, R. A. Ammann, and J. Pfenninger, “Reproducibility of the blood flow index as noninvasive, bedside estimation of cerebral blood flow,” Intensive Care Med. 29(2), 196–200 (2003).
[PubMed]

Piepgras, A.

A. Piepgras, P. Schmiedek, G. Leinsinger, R. L. Haberl, C. M. Kirsch, and K. M. Einhäupl, “A simple test to assess cerebrovascular reserve capacity using transcranial Doppler sonography and acetazolamide,” Stroke 21(9), 1306–1311 (1990).
[PubMed]

Pifferi, A.

A. Torricelli, A. Pifferi, P. Taroni, E. Giambattistelli, and R. Cubeddu, “In vivo optical characterization of human tissues from 610 to 1010 nm by time-resolved reflectance spectroscopy,” Phys. Med. Biol. 46(8), 2227–2237 (2001).
[CrossRef] [PubMed]

Pike, G. B.

R. D. Hoge, J. Atkinson, B. Gill, G. R. Crelier, S. Marrett, and G. B. Pike, “Linear coupling between cerebral blood flow and oxygen consumption in activated human cortex,” Proc. Natl. Acad. Sci. U.S.A. 96(16), 9403–9408 (1999).
[CrossRef] [PubMed]

Plum, F.

J. B. Posner and F. Plum, “The toxic effects of carbon dioxide and acetazolamide in hepatic encephalopathy,” J. Clin. Invest. 39(8), 1246–1258 (1960).
[CrossRef] [PubMed]

Poldrack, R. A.

D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003).
[CrossRef] [PubMed]

Ponchel, E.

N. Roche-Labarbe, F. Wallois, E. Ponchel, G. Kongolo, and R. Grebe, “Coupled oxygenation oscillation measured by NIRS and intermittent cerebral activation on EEG in premature infants,” Neuroimage 36(3), 718–727 (2007).
[CrossRef] [PubMed]

Posner, J. B.

J. B. Posner and F. Plum, “The toxic effects of carbon dioxide and acetazolamide in hepatic encephalopathy,” J. Clin. Invest. 39(8), 1246–1258 (1960).
[CrossRef] [PubMed]

Potter, L. A.

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Roth, E. O. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult head, calf and forearm and the head of the newborn infant as a function of inter optode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[PubMed]

Powers, W. J.

W. J. Powers, L. W. Tempel, and R. L. Grubb., “Influence of cerebral hemodynamics on stroke risk: one-year follow-up of 30 medically treated patients,” Ann. Neurol. 25(4), 325–330 (1989).
[CrossRef] [PubMed]

Pritchard, C.

T. S. Leung, I. Tachtsidis, M. M. Tisdall, C. Pritchard, M. Smith, and C. E. Elwell, “Estimating a modified Grubb’s exponent in healthy human brains with near infrared spectroscopy and transcranial Doppler,” Physiol. Meas. 30(1), 1–12 (2009).
[CrossRef] [PubMed]

Putt, M. E.

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, “Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients,” Opt. Express 17(5), 3884–3902 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

Raichle, M. E.

B. E. Laux and M. E. Raichle, “The effect of acetazolamide on cerebral blood flow and oxygen utilization in the rhesus monkey,” J. Clin. Invest. 62(3), 585–592 (1978).
[CrossRef] [PubMed]

R. L. Grubb, M. E. Raichle, J. O. Eichling, and M. M. Ter-Pogossian, “The effects of changes in PaCO2 on cerebral blood volume, blood flow, and vascular mean transit time,” Stroke 5(5), 630–639 (1974).
[PubMed]

Raps, E. C.

J. A. Detre, O. B. Samuels, D. C. Alsop, J. B. Gonzalez-At, S. E. Kasner, and E. C. Raps, “Noninvasive magnetic resonance imaging evaluation of cerebral blood flow with acetazolamide challenge in patients with cerebrovascular stenosis,” J. Magn. Reson. Imaging 10(5), 870–875 (1999).
[CrossRef] [PubMed]

Rascol, A.

U. Sabatini, P. Celsis, G. Viallard, A. Rascol, and J. P. Marc-Vergnes, “Quantitative assessment of cerebral blood volume by single-photon emission computed tomography,” Stroke 22(3), 324–330 (1991).
[PubMed]

Reynolds, E. O.

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Roth, E. O. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult head, calf and forearm and the head of the newborn infant as a function of inter optode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[PubMed]

Roche-Labarbe, N.

N. Roche-Labarbe, S. A. Carp, A. Surova, M. Patel, D. A. Boas, P. E. Grant, and M. A. Franceschini, “Noninvasive optical measures of CBV, StO(2), CBF index, and rCMRO(2) in human premature neonates’ brains in the first six weeks of life,” Hum. Brain Mapp. 31(3), 341–352 (2010).
[PubMed]

N. Roche-Labarbe, F. Wallois, E. Ponchel, G. Kongolo, and R. Grebe, “Coupled oxygenation oscillation measured by NIRS and intermittent cerebral activation on EEG in premature infants,” Neuroimage 36(3), 718–727 (2007).
[CrossRef] [PubMed]

Rockstroh, B.

J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J. Biomed. Opt. 10(4), 044002 (2005).
[CrossRef] [PubMed]

Rootwelt, K.

A. Dahl, D. Russell, R. Nyberg-Hansen, K. Rootwelt, and P. Mowinckel, “Simultaneous assessment of vasoreactivity using transcranial Doppler ultrasound and cerebral blood flow in healthy subjects,” J. Cereb. Blood Flow Metab. 14(6), 974–981 (1994).
[PubMed]

A. Dahl, K. F. Lindegaard, D. Russell, R. Nyberg-Hansen, K. Rootwelt, W. Sorteberg, and H. Nornes, “A comparison of transcranial Doppler and cerebral blood flow studies to assess cerebral vasoreactivity,” Stroke 23(1), 15–19 (1992).
[PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, R. Nyberg-Hansen, D. Russell, and H. Nornes, “Effect of acetazolamide on cerebral artery blood velocity and regional cerebral blood flow in normal subjects,” Acta Neurochir. (Wien) 97(3-4), 139–145 (1989).
[CrossRef] [PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, D. Russell, R. Nyberg-Hansen, and H. Nornes, “Blood velocity and regional blood flow in defined cerebral artery systems,” Acta Neurochir. (Wien) 97(1-2), 47–52 (1989).
[CrossRef] [PubMed]

Rosen, B. R.

D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003).
[CrossRef] [PubMed]

T. L. Davis, K. K. Kwong, R. M. Weisskoff, and B. R. Rosen, “Calibrated functional MRI: mapping the dynamics of oxidative metabolism,” Proc. Natl. Acad. Sci. U.S.A. 95(4), 1834–1839 (1998).
[CrossRef] [PubMed]

Roski, R.

R. Roski, R. F. Spetzler, M. Owen, K. Chandar, J. G. Sholl, and F. E. Nulsen, “Reversal of seven-year old visual field defect with extracranial-intracranial arterial anastomosis,” Surg. Neurol. 10(4), 267–268 (1978).
[PubMed]

Rostrup, E.

S. G. Kim, E. Rostrup, H. B. Larsson, S. Ogawa, and O. B. Paulson, “Determination of relative CMRO2 from CBF and BOLD changes: significant increase of oxygen consumption rate during visual stimulation,” Magn. Reson. Med. 41(6), 1152–1161 (1999).
[CrossRef] [PubMed]

Roth, S. C.

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Roth, E. O. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult head, calf and forearm and the head of the newborn infant as a function of inter optode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[PubMed]

Russell, D.

A. Dahl, D. Russell, R. Nyberg-Hansen, K. Rootwelt, and P. Mowinckel, “Simultaneous assessment of vasoreactivity using transcranial Doppler ultrasound and cerebral blood flow in healthy subjects,” J. Cereb. Blood Flow Metab. 14(6), 974–981 (1994).
[PubMed]

A. Dahl, K. F. Lindegaard, D. Russell, R. Nyberg-Hansen, K. Rootwelt, W. Sorteberg, and H. Nornes, “A comparison of transcranial Doppler and cerebral blood flow studies to assess cerebral vasoreactivity,” Stroke 23(1), 15–19 (1992).
[PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, R. Nyberg-Hansen, D. Russell, and H. Nornes, “Effect of acetazolamide on cerebral artery blood velocity and regional cerebral blood flow in normal subjects,” Acta Neurochir. (Wien) 97(3-4), 139–145 (1989).
[CrossRef] [PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, D. Russell, R. Nyberg-Hansen, and H. Nornes, “Blood velocity and regional blood flow in defined cerebral artery systems,” Acta Neurochir. (Wien) 97(1-2), 47–52 (1989).
[CrossRef] [PubMed]

Rutigliano, M.

S. Durham, H. Smith, M. Rutigliano, and H. Yonas, “Assessment of cerebral vasoreactivity and stroke risk using Xe-CT acetazolamide challenge,” Stroke 22, 138 (1991).

Sabatini, U.

U. Sabatini, P. Celsis, G. Viallard, A. Rascol, and J. P. Marc-Vergnes, “Quantitative assessment of cerebral blood volume by single-photon emission computed tomography,” Stroke 22(3), 324–330 (1991).
[PubMed]

Samuels, O. B.

J. A. Detre, O. B. Samuels, D. C. Alsop, J. B. Gonzalez-At, S. E. Kasner, and E. C. Raps, “Noninvasive magnetic resonance imaging evaluation of cerebral blood flow with acetazolamide challenge in patients with cerebrovascular stenosis,” J. Magn. Reson. Imaging 10(5), 870–875 (1999).
[CrossRef] [PubMed]

Schmiedek, P.

A. Piepgras, P. Schmiedek, G. Leinsinger, R. L. Haberl, C. M. Kirsch, and K. M. Einhäupl, “A simple test to assess cerebrovascular reserve capacity using transcranial Doppler sonography and acetazolamide,” Stroke 21(9), 1306–1311 (1990).
[PubMed]

T. Kreisig, P. Schmiedek, G. Leinsinger, K. Einhäupl, and E. Moser, “[133Xe-DSPECT: normal values of resting cerebral blood flow and reserve capacity],” Nucl. Med. (Stuttg.) 26(5), 192–197 (1987).
[PubMed]

Schultz, S.

Schytz, H. W.

H. W. Schytz, T. Wienecke, L. T. Jensen, J. Selb, D. A. Boas, and M. Ashina, “Changes in cerebral blood flow after acetazolamide: an experimental study comparing near-infrared spectroscopy and SPECT,” Eur. J. Neurol. 16(4), 461–467 (2009).
[CrossRef] [PubMed]

Sehgal, C. M.

Selb, J.

H. W. Schytz, T. Wienecke, L. T. Jensen, J. Selb, D. A. Boas, and M. Ashina, “Changes in cerebral blood flow after acetazolamide: an experimental study comparing near-infrared spectroscopy and SPECT,” Eur. J. Neurol. 16(4), 461–467 (2009).
[CrossRef] [PubMed]

Settakis, G.

G. Settakis, C. Molnár, L. Kerényi, J. Kollár, D. Legemate, L. Csiba, and B. Fülesdi, “Acetazolamide as a vasodilatory stimulus in cerebrovascular diseases and in conditions affecting the cerebral vasculature,” Eur. J. Neurol. 10(6), 609–620 (2003).
[CrossRef] [PubMed]

Seylaz, J.

P. Démolis, G. Florence, L. Thomas, Y. R. Tran Dinh, J. F. Giudicelli, J. Seylaz, and N. J. Alkayed, “Is the acetazolamide test valid for quantitative assessment of maximal cerebral autoregulatory vasodilation? An experimental study,” Stroke 31(2), 508–515 (2000).
[PubMed]

Shah, Q.

Shibata, S.

M. Kaminogo, A. Ichikura, S. Shibata, T. Toba, and M. Yonekura, “Effect of acetazolamide on regional cerebral oxygen saturation and regional cerebral blood flow,” Stroke 26(12), 2358–2360 (1995).
[PubMed]

Sholl, J. G.

R. Roski, R. F. Spetzler, M. Owen, K. Chandar, J. G. Sholl, and F. E. Nulsen, “Reversal of seven-year old visual field defect with extracranial-intracranial arterial anastomosis,” Surg. Neurol. 10(4), 267–268 (1978).
[PubMed]

Sila, C. A.

M. I. Chimowitz, A. J. Furlan, S. C. Jones, C. A. Sila, R. L. Lorig, L. Paranandi, and G. J. Beck, “Transcranial Doppler assessment of cerebral perfusion reserve in patients with carotid occlusive disease and no evidence of cerebral infarction,” Neurology 43(2), 353–357 (1993).
[PubMed]

Silander, H. C.

P. Frykholm, J. L. R. Andersson, J. Valtysson, H. C. Silander, L. Hillered, L. Persson, Y. Olsson, W. R. Yu, G. Westerberg, Y. Watanabe, B. Långström, and P. Enblad, “A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion-reperfusion primate model,” Acta Neurol. Scand. 102(1), 18–26 (2000).
[CrossRef] [PubMed]

Silvestrini, M.

M. Matteis, E. Troisi, B. C. Monaldo, C. Caltagirone, and M. Silvestrini, “Age and sex differences in cerebral hemodynamics: a transcranial Doppler study,” Stroke 29(5), 963–967 (1998).
[PubMed]

Skipetrov, S. E.

J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J. Biomed. Opt. 10(4), 044002 (2005).
[CrossRef] [PubMed]

Smith, H.

S. Durham, H. Smith, M. Rutigliano, and H. Yonas, “Assessment of cerebral vasoreactivity and stroke risk using Xe-CT acetazolamide challenge,” Stroke 22, 138 (1991).

Smith, M.

T. S. Leung, I. Tachtsidis, M. M. Tisdall, C. Pritchard, M. Smith, and C. E. Elwell, “Estimating a modified Grubb’s exponent in healthy human brains with near infrared spectroscopy and transcranial Doppler,” Physiol. Meas. 30(1), 1–12 (2009).
[CrossRef] [PubMed]

I. Tachtsidis, M. Tisdall, D. T. Delpy, M. Smith, and C. E. Elwell, “Measurement of cerebral tissue oxygenation in young healthy volunteers during acetazolamide provocation: a transcranial Doppler and near-infrared spectroscopy investigation,” Adv. Exp. Med. Biol. 614, 389–396 (2008).
[CrossRef] [PubMed]

Sorteberg, W.

A. Dahl, K. F. Lindegaard, D. Russell, R. Nyberg-Hansen, K. Rootwelt, W. Sorteberg, and H. Nornes, “A comparison of transcranial Doppler and cerebral blood flow studies to assess cerebral vasoreactivity,” Stroke 23(1), 15–19 (1992).
[PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, R. Nyberg-Hansen, D. Russell, and H. Nornes, “Effect of acetazolamide on cerebral artery blood velocity and regional cerebral blood flow in normal subjects,” Acta Neurochir. (Wien) 97(3-4), 139–145 (1989).
[CrossRef] [PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, D. Russell, R. Nyberg-Hansen, and H. Nornes, “Blood velocity and regional blood flow in defined cerebral artery systems,” Acta Neurochir. (Wien) 97(1-2), 47–52 (1989).
[CrossRef] [PubMed]

Spetzler, R. F.

R. Roski, R. F. Spetzler, M. Owen, K. Chandar, J. G. Sholl, and F. E. Nulsen, “Reversal of seven-year old visual field defect with extracranial-intracranial arterial anastomosis,” Surg. Neurol. 10(4), 267–268 (1978).
[PubMed]

Spray, T. L.

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

Strangman, G.

G. Strangman, M. A. Franceschini, and D. A. Boas, “Factors affecting the accuracy of near-infrared spectroscopy concentration calculations for focal changes in oxygenation parameters,” Neuroimage 18(4), 865–879 (2003).
[CrossRef] [PubMed]

D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003).
[CrossRef] [PubMed]

Surgeon, C.

M. L. Dyken, E. Klatte, O. J. Kolar, and C. Surgeon, “Complete occlusion of common or internal carotid arteries. Clinical significance,” Arch. Neurol. 30(5), 343–346 (1974).
[PubMed]

Surova, A.

N. Roche-Labarbe, S. A. Carp, A. Surova, M. Patel, D. A. Boas, P. E. Grant, and M. A. Franceschini, “Noninvasive optical measures of CBV, StO(2), CBF index, and rCMRO(2) in human premature neonates’ brains in the first six weeks of life,” Hum. Brain Mapp. 31(3), 341–352 (2010).
[PubMed]

Tachtsidis, I.

T. S. Leung, I. Tachtsidis, M. M. Tisdall, C. Pritchard, M. Smith, and C. E. Elwell, “Estimating a modified Grubb’s exponent in healthy human brains with near infrared spectroscopy and transcranial Doppler,” Physiol. Meas. 30(1), 1–12 (2009).
[CrossRef] [PubMed]

I. Tachtsidis, M. Tisdall, D. T. Delpy, M. Smith, and C. E. Elwell, “Measurement of cerebral tissue oxygenation in young healthy volunteers during acetazolamide provocation: a transcranial Doppler and near-infrared spectroscopy investigation,” Adv. Exp. Med. Biol. 614, 389–396 (2008).
[CrossRef] [PubMed]

Takahashi, A. M.

Y. F. Yen, A. S. Field, E. M. Martin, N. Ari, J. H. Burdette, D. M. Moody, and A. M. Takahashi, “Test-retest reproducibility of quantitative CBF measurements using FAIR perfusion MRI and acetazolamide challenge,” Magn. Reson. Med. 47(5), 921–928 (2002).
[CrossRef] [PubMed]

Tamaki, N.

S. Kohri, Y. Hoshi, M. Tamura, C. Kato, Y. Kuge, and N. Tamaki, “Quantitative evaluation of the relative contribution ratio of cerebral tissue to near-infrared signals in the adult human head: a preliminary study,” Physiol. Meas. 23(2), 301–312 (2002).
[CrossRef] [PubMed]

Tamura, M.

S. Kohri, Y. Hoshi, M. Tamura, C. Kato, Y. Kuge, and N. Tamaki, “Quantitative evaluation of the relative contribution ratio of cerebral tissue to near-infrared signals in the adult human head: a preliminary study,” Physiol. Meas. 23(2), 301–312 (2002).
[CrossRef] [PubMed]

Taroni, P.

A. Torricelli, A. Pifferi, P. Taroni, E. Giambattistelli, and R. Cubeddu, “In vivo optical characterization of human tissues from 610 to 1010 nm by time-resolved reflectance spectroscopy,” Phys. Med. Biol. 46(8), 2227–2237 (2001).
[CrossRef] [PubMed]

Taylor, D. W.

R. Cote, H. J. Barnett, and D. W. Taylor, “Internal carotid occlusion: a prospective study,” Stroke 14(6), 898–902 (1983).
[PubMed]

Tempel, L. W.

W. J. Powers, L. W. Tempel, and R. L. Grubb., “Influence of cerebral hemodynamics on stroke risk: one-year follow-up of 30 medically treated patients,” Ann. Neurol. 25(4), 325–330 (1989).
[CrossRef] [PubMed]

Ter-Pogossian, M. M.

R. L. Grubb, M. E. Raichle, J. O. Eichling, and M. M. Ter-Pogossian, “The effects of changes in PaCO2 on cerebral blood volume, blood flow, and vascular mean transit time,” Stroke 5(5), 630–639 (1974).
[PubMed]

Thomas, L.

P. Démolis, G. Florence, L. Thomas, Y. R. Tran Dinh, J. F. Giudicelli, J. Seylaz, and N. J. Alkayed, “Is the acetazolamide test valid for quantitative assessment of maximal cerebral autoregulatory vasodilation? An experimental study,” Stroke 31(2), 508–515 (2000).
[PubMed]

Tisdall, M.

I. Tachtsidis, M. Tisdall, D. T. Delpy, M. Smith, and C. E. Elwell, “Measurement of cerebral tissue oxygenation in young healthy volunteers during acetazolamide provocation: a transcranial Doppler and near-infrared spectroscopy investigation,” Adv. Exp. Med. Biol. 614, 389–396 (2008).
[CrossRef] [PubMed]

Tisdall, M. M.

T. S. Leung, I. Tachtsidis, M. M. Tisdall, C. Pritchard, M. Smith, and C. E. Elwell, “Estimating a modified Grubb’s exponent in healthy human brains with near infrared spectroscopy and transcranial Doppler,” Physiol. Meas. 30(1), 1–12 (2009).
[CrossRef] [PubMed]

Toba, T.

M. Kaminogo, A. Ichikura, S. Shibata, T. Toba, and M. Yonekura, “Effect of acetazolamide on regional cerebral oxygen saturation and regional cerebral blood flow,” Stroke 26(12), 2358–2360 (1995).
[PubMed]

Toronov, V.

Torricelli, A.

A. Torricelli, A. Pifferi, P. Taroni, E. Giambattistelli, and R. Cubeddu, “In vivo optical characterization of human tissues from 610 to 1010 nm by time-resolved reflectance spectroscopy,” Phys. Med. Biol. 46(8), 2227–2237 (2001).
[CrossRef] [PubMed]

Tran Dinh, Y. R.

P. Démolis, G. Florence, L. Thomas, Y. R. Tran Dinh, J. F. Giudicelli, J. Seylaz, and N. J. Alkayed, “Is the acetazolamide test valid for quantitative assessment of maximal cerebral autoregulatory vasodilation? An experimental study,” Stroke 31(2), 508–515 (2000).
[PubMed]

Treyer, V.

B. Weber, G. Westera, V. Treyer, C. Burger, N. Khan, and A. Buck, “Constant-infusion H(2)15O PET and acetazolamide challenge in the assessment of cerebral perfusion status,” J. Nucl. Med. 45(8), 1344–1350 (2004).
[PubMed]

Troisi, E.

M. Matteis, E. Troisi, B. C. Monaldo, C. Caltagirone, and M. Silvestrini, “Age and sex differences in cerebral hemodynamics: a transcranial Doppler study,” Stroke 29(5), 963–967 (1998).
[PubMed]

Tyszczuk, L.

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304 (1995).
[CrossRef] [PubMed]

Ulrich, P. T.

P. T. Ulrich, T. Becker, and O. S. Kempski, “Correlation of cerebral blood flow and MCA flow velocity measured in healthy volunteers during acetazolamide and CO2 stimulation,” J. Neurol. Sci. 129(2), 120–130 (1995).
[CrossRef] [PubMed]

Valtysson, J.

P. Frykholm, J. L. R. Andersson, J. Valtysson, H. C. Silander, L. Hillered, L. Persson, Y. Olsson, W. R. Yu, G. Westerberg, Y. Watanabe, B. Långström, and P. Enblad, “A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion-reperfusion primate model,” Acta Neurol. Scand. 102(1), 18–26 (2000).
[CrossRef] [PubMed]

van der Zee, P.

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Roth, E. O. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult head, calf and forearm and the head of the newborn infant as a function of inter optode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[PubMed]

Viallard, G.

U. Sabatini, P. Celsis, G. Viallard, A. Rascol, and J. P. Marc-Vergnes, “Quantitative assessment of cerebral blood volume by single-photon emission computed tomography,” Stroke 22(3), 324–330 (1991).
[PubMed]

Villringer, A.

A. Villringer and B. Chance, “Non-invasive optical spectroscopy and imaging of human brain function,” Trends Neurosci. 20(10), 435–442 (1997).
[CrossRef] [PubMed]

Vorstrup, S.

S. Vorstrup, L. Henriksen, and O. B. Paulson, “Effect of acetazolamide on cerebral blood flow and cerebral metabolic rate for oxygen,” J. Clin. Invest. 74(5), 1634–1639 (1984).
[CrossRef] [PubMed]

Wagner, B. P.

B. P. Wagner, S. Gertsch, R. A. Ammann, and J. Pfenninger, “Reproducibility of the blood flow index as noninvasive, bedside estimation of cerebral blood flow,” Intensive Care Med. 29(2), 196–200 (2003).
[PubMed]

Wallois, F.

N. Roche-Labarbe, F. Wallois, E. Ponchel, G. Kongolo, and R. Grebe, “Coupled oxygenation oscillation measured by NIRS and intermittent cerebral activation on EEG in premature infants,” Neuroimage 36(3), 718–727 (2007).
[CrossRef] [PubMed]

Wang, J.

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse optical measurement of blood flow, blood oxygenation, and metabolism in a human brain during sensorimotor cortex activation,” Opt. Lett. 29(15), 1766–1768 (2004).
[CrossRef] [PubMed]

Watanabe, Y.

P. Frykholm, J. L. R. Andersson, J. Valtysson, H. C. Silander, L. Hillered, L. Persson, Y. Olsson, W. R. Yu, G. Westerberg, Y. Watanabe, B. Långström, and P. Enblad, “A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion-reperfusion primate model,” Acta Neurol. Scand. 102(1), 18–26 (2000).
[CrossRef] [PubMed]

Webb, A.

Weber, B.

B. Weber, G. Westera, V. Treyer, C. Burger, N. Khan, and A. Buck, “Constant-infusion H(2)15O PET and acetazolamide challenge in the assessment of cerebral perfusion status,” J. Nucl. Med. 45(8), 1344–1350 (2004).
[PubMed]

Weisskoff, R. M.

T. L. Davis, K. K. Kwong, R. M. Weisskoff, and B. R. Rosen, “Calibrated functional MRI: mapping the dynamics of oxidative metabolism,” Proc. Natl. Acad. Sci. U.S.A. 95(4), 1834–1839 (1998).
[CrossRef] [PubMed]

Westera, G.

B. Weber, G. Westera, V. Treyer, C. Burger, N. Khan, and A. Buck, “Constant-infusion H(2)15O PET and acetazolamide challenge in the assessment of cerebral perfusion status,” J. Nucl. Med. 45(8), 1344–1350 (2004).
[PubMed]

Westerberg, G.

P. Frykholm, J. L. R. Andersson, J. Valtysson, H. C. Silander, L. Hillered, L. Persson, Y. Olsson, W. R. Yu, G. Westerberg, Y. Watanabe, B. Långström, and P. Enblad, “A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion-reperfusion primate model,” Acta Neurol. Scand. 102(1), 18–26 (2000).
[CrossRef] [PubMed]

Widder, B.

B. Widder, B. Kleiser, and H. Krapf, “Course of cerebrovascular reactivity in patients with carotid artery occlusions,” Stroke 25(10), 1963–1967 (1994).
[PubMed]

B. Kleiser and B. Widder, “Course of carotid artery occlusions with impaired cerebrovascular reactivity,” Stroke 23(2), 171–174 (1992).
[PubMed]

Wienecke, T.

H. W. Schytz, T. Wienecke, L. T. Jensen, J. Selb, D. A. Boas, and M. Ashina, “Changes in cerebral blood flow after acetazolamide: an experimental study comparing near-infrared spectroscopy and SPECT,” Eur. J. Neurol. 16(4), 461–467 (2009).
[CrossRef] [PubMed]

Woertgen, C.

M. Holzschuh, C. Woertgen, C. Metz, and A. Brawanski, “Comparison of changes in cerebral blood flow and cerebral oxygen saturation measured by near infrared spectroscopy (NIRS) after acetazolamide,” Acta Neurochir. (Wien) 139(1), 58–62 (1997).
[CrossRef] [PubMed]

Wolf, M.

E. Keller, M. Wolf, M. Martin, and Y. Yonekawa, “Estimation of cerebral oxygenation and hemodynamics in cerebral vasospasm using indocyaningreen dye dilution and near infrared spectroscopy: a case report,” J. Neurosurg. Anesthesiol. 13(1), 43–48 (2001).
[CrossRef] [PubMed]

Wolf, R. L.

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

Wyatt, J. S.

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Roth, E. O. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult head, calf and forearm and the head of the newborn infant as a function of inter optode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[PubMed]

Yamaguchi, H.

H. Yamaguchi, H. Yamauchi, S. Hazama, H. Hamamoto, and N. Inoue, “Correlation between cerebral oxygen metabolism and cerebral blood flow simultaneously measured before and after acetazolamide administration,” J. Biomed. Opt. 4(4), 418 (1999).
[CrossRef]

Yamauchi, H.

H. Yamaguchi, H. Yamauchi, S. Hazama, H. Hamamoto, and N. Inoue, “Correlation between cerebral oxygen metabolism and cerebral blood flow simultaneously measured before and after acetazolamide administration,” J. Biomed. Opt. 4(4), 418 (1999).
[CrossRef]

Yen, Y. F.

Y. F. Yen, A. S. Field, E. M. Martin, N. Ari, J. H. Burdette, D. M. Moody, and A. M. Takahashi, “Test-retest reproducibility of quantitative CBF measurements using FAIR perfusion MRI and acetazolamide challenge,” Magn. Reson. Med. 47(5), 921–928 (2002).
[CrossRef] [PubMed]

Yodh, A.

Yodh, A. G.

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

T. Durduran, R. Choe, W. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010).
[CrossRef]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, “Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients,” Opt. Express 17(5), 3884–3902 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse optical measurement of blood flow, blood oxygenation, and metabolism in a human brain during sensorimotor cortex activation,” Opt. Lett. 29(15), 1766–1768 (2004).
[CrossRef] [PubMed]

J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003).
[CrossRef] [PubMed]

D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and imaging with diffusing temporal field correlations,” Phys. Rev. Lett. 75(9), 1855–1858 (1995).
[CrossRef] [PubMed]

Yonas, H.

S. Durham, H. Smith, M. Rutigliano, and H. Yonas, “Assessment of cerebral vasoreactivity and stroke risk using Xe-CT acetazolamide challenge,” Stroke 22, 138 (1991).

Yonekawa, Y.

E. Keller, M. Wolf, M. Martin, and Y. Yonekawa, “Estimation of cerebral oxygenation and hemodynamics in cerebral vasospasm using indocyaningreen dye dilution and near infrared spectroscopy: a case report,” J. Neurosurg. Anesthesiol. 13(1), 43–48 (2001).
[CrossRef] [PubMed]

Yonekura, M.

M. Kaminogo, A. Ichikura, S. Shibata, T. Toba, and M. Yonekura, “Effect of acetazolamide on regional cerebral oxygen saturation and regional cerebral blood flow,” Stroke 26(12), 2358–2360 (1995).
[PubMed]

Yu, G.

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, “Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients,” Opt. Express 17(5), 3884–3902 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse optical measurement of blood flow, blood oxygenation, and metabolism in a human brain during sensorimotor cortex activation,” Opt. Lett. 29(15), 1766–1768 (2004).
[CrossRef] [PubMed]

Yu, W. R.

P. Frykholm, J. L. R. Andersson, J. Valtysson, H. C. Silander, L. Hillered, L. Persson, Y. Olsson, W. R. Yu, G. Westerberg, Y. Watanabe, B. Långström, and P. Enblad, “A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion-reperfusion primate model,” Acta Neurol. Scand. 102(1), 18–26 (2000).
[CrossRef] [PubMed]

Zheng, Y.

J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001).
[CrossRef] [PubMed]

Zhou, C.

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, “Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients,” Opt. Express 17(5), 3884–3902 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse optical measurement of blood flow, blood oxygenation, and metabolism in a human brain during sensorimotor cortex activation,” Opt. Lett. 29(15), 1766–1768 (2004).
[CrossRef] [PubMed]

Zimmerman, R. A.

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

Acta Diabetol. (1)

B. Fülesdi, M. Limburg, L. Oláh, D. Bereczki, L. Csiba, and J. Kollár, “Lack of gender difference in acetazolamide-induced cerebral vasomotor reactivity in patients suffering from type-1 diabetes mellitus,” Acta Diabetol. 38(3), 107–112 (2001).
[CrossRef] [PubMed]

Acta Neurochir. (Wien) (3)

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, R. Nyberg-Hansen, D. Russell, and H. Nornes, “Effect of acetazolamide on cerebral artery blood velocity and regional cerebral blood flow in normal subjects,” Acta Neurochir. (Wien) 97(3-4), 139–145 (1989).
[CrossRef] [PubMed]

M. Holzschuh, C. Woertgen, C. Metz, and A. Brawanski, “Comparison of changes in cerebral blood flow and cerebral oxygen saturation measured by near infrared spectroscopy (NIRS) after acetazolamide,” Acta Neurochir. (Wien) 139(1), 58–62 (1997).
[CrossRef] [PubMed]

W. Sorteberg, K. F. Lindegaard, K. Rootwelt, A. Dahl, D. Russell, R. Nyberg-Hansen, and H. Nornes, “Blood velocity and regional blood flow in defined cerebral artery systems,” Acta Neurochir. (Wien) 97(1-2), 47–52 (1989).
[CrossRef] [PubMed]

Acta Neurol. Scand. (1)

P. Frykholm, J. L. R. Andersson, J. Valtysson, H. C. Silander, L. Hillered, L. Persson, Y. Olsson, W. R. Yu, G. Westerberg, Y. Watanabe, B. Långström, and P. Enblad, “A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion-reperfusion primate model,” Acta Neurol. Scand. 102(1), 18–26 (2000).
[CrossRef] [PubMed]

Adv. Exp. Med. Biol. (2)

I. Tachtsidis, M. Tisdall, D. T. Delpy, M. Smith, and C. E. Elwell, “Measurement of cerebral tissue oxygenation in young healthy volunteers during acetazolamide provocation: a transcranial Doppler and near-infrared spectroscopy investigation,” Adv. Exp. Med. Biol. 614, 389–396 (2008).
[CrossRef] [PubMed]

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Roth, E. O. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult head, calf and forearm and the head of the newborn infant as a function of inter optode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[PubMed]

Adv. Neurol. (1)

A. L. Carney and E. M. Anderson, “The system approach to brain blood flow,” Adv. Neurol. 30, 1–30 (1981).
[PubMed]

Ann. Neurol. (1)

W. J. Powers, L. W. Tempel, and R. L. Grubb., “Influence of cerebral hemodynamics on stroke risk: one-year follow-up of 30 medically treated patients,” Ann. Neurol. 25(4), 325–330 (1989).
[CrossRef] [PubMed]

Arch. Neurol. (2)

D. L. Ehrenreich, R. A. Burns, R. W. Alman, and J. F. Fazekas, “Influence of acetazolamide on cerebral blood flow,” Arch. Neurol. 5, 227–232 (1961).
[PubMed]

M. L. Dyken, E. Klatte, O. J. Kolar, and C. Surgeon, “Complete occlusion of common or internal carotid arteries. Clinical significance,” Arch. Neurol. 30(5), 343–346 (1974).
[PubMed]

Arch. Neurol. Psychiatry (1)

M. Fog, “Cerebral circulation: the reaction of the pial arteries to a fall in blood pressure,” Arch. Neurol. Psychiatry 37, 351 (1937).

Biomed. Opt. Express (1)

Eur. J. Neurol. (2)

H. W. Schytz, T. Wienecke, L. T. Jensen, J. Selb, D. A. Boas, and M. Ashina, “Changes in cerebral blood flow after acetazolamide: an experimental study comparing near-infrared spectroscopy and SPECT,” Eur. J. Neurol. 16(4), 461–467 (2009).
[CrossRef] [PubMed]

G. Settakis, C. Molnár, L. Kerényi, J. Kollár, D. Legemate, L. Csiba, and B. Fülesdi, “Acetazolamide as a vasodilatory stimulus in cerebrovascular diseases and in conditions affecting the cerebral vasculature,” Eur. J. Neurol. 10(6), 609–620 (2003).
[CrossRef] [PubMed]

Hum. Brain Mapp. (1)

N. Roche-Labarbe, S. A. Carp, A. Surova, M. Patel, D. A. Boas, P. E. Grant, and M. A. Franceschini, “Noninvasive optical measures of CBV, StO(2), CBF index, and rCMRO(2) in human premature neonates’ brains in the first six weeks of life,” Hum. Brain Mapp. 31(3), 341–352 (2010).
[PubMed]

Intensive Care Med. (1)

B. P. Wagner, S. Gertsch, R. A. Ammann, and J. Pfenninger, “Reproducibility of the blood flow index as noninvasive, bedside estimation of cerebral blood flow,” Intensive Care Med. 29(2), 196–200 (2003).
[PubMed]

J. Biomed. Opt. (4)

E. M. Hillman, “Optical brain imaging in vivo: techniques and applications from animal to man,” J. Biomed. Opt. 12(5), 051402 (2007).
[CrossRef] [PubMed]

H. Yamaguchi, H. Yamauchi, S. Hazama, H. Hamamoto, and N. Inoue, “Correlation between cerebral oxygen metabolism and cerebral blood flow simultaneously measured before and after acetazolamide administration,” J. Biomed. Opt. 4(4), 418 (1999).
[CrossRef]

J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J. Biomed. Opt. 10(4), 044002 (2005).
[CrossRef] [PubMed]

T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010).
[CrossRef] [PubMed]

J. Cereb. Blood Flow Metab. (2)

J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003).
[CrossRef] [PubMed]

A. Dahl, D. Russell, R. Nyberg-Hansen, K. Rootwelt, and P. Mowinckel, “Simultaneous assessment of vasoreactivity using transcranial Doppler ultrasound and cerebral blood flow in healthy subjects,” J. Cereb. Blood Flow Metab. 14(6), 974–981 (1994).
[PubMed]

J. Clin. Invest. (3)

J. B. Posner and F. Plum, “The toxic effects of carbon dioxide and acetazolamide in hepatic encephalopathy,” J. Clin. Invest. 39(8), 1246–1258 (1960).
[CrossRef] [PubMed]

B. E. Laux and M. E. Raichle, “The effect of acetazolamide on cerebral blood flow and oxygen utilization in the rhesus monkey,” J. Clin. Invest. 62(3), 585–592 (1978).
[CrossRef] [PubMed]

S. Vorstrup, L. Henriksen, and O. B. Paulson, “Effect of acetazolamide on cerebral blood flow and cerebral metabolic rate for oxygen,” J. Clin. Invest. 74(5), 1634–1639 (1984).
[CrossRef] [PubMed]

J. Magn. Reson. Imaging (1)

J. A. Detre, O. B. Samuels, D. C. Alsop, J. B. Gonzalez-At, S. E. Kasner, and E. C. Raps, “Noninvasive magnetic resonance imaging evaluation of cerebral blood flow with acetazolamide challenge in patients with cerebrovascular stenosis,” J. Magn. Reson. Imaging 10(5), 870–875 (1999).
[CrossRef] [PubMed]

J. Neurol. Sci. (1)

P. T. Ulrich, T. Becker, and O. S. Kempski, “Correlation of cerebral blood flow and MCA flow velocity measured in healthy volunteers during acetazolamide and CO2 stimulation,” J. Neurol. Sci. 129(2), 120–130 (1995).
[CrossRef] [PubMed]

J. Neurosurg. Anesthesiol. (1)

E. Keller, M. Wolf, M. Martin, and Y. Yonekawa, “Estimation of cerebral oxygenation and hemodynamics in cerebral vasospasm using indocyaningreen dye dilution and near infrared spectroscopy: a case report,” J. Neurosurg. Anesthesiol. 13(1), 43–48 (2001).
[CrossRef] [PubMed]

J. Nucl. Med. (1)

B. Weber, G. Westera, V. Treyer, C. Burger, N. Khan, and A. Buck, “Constant-infusion H(2)15O PET and acetazolamide challenge in the assessment of cerebral perfusion status,” J. Nucl. Med. 45(8), 1344–1350 (2004).
[PubMed]

J. Opt. Soc. Am. A (1)

Magn. Reson. Med. (2)

S. G. Kim, E. Rostrup, H. B. Larsson, S. Ogawa, and O. B. Paulson, “Determination of relative CMRO2 from CBF and BOLD changes: significant increase of oxygen consumption rate during visual stimulation,” Magn. Reson. Med. 41(6), 1152–1161 (1999).
[CrossRef] [PubMed]

Y. F. Yen, A. S. Field, E. M. Martin, N. Ari, J. H. Burdette, D. M. Moody, and A. M. Takahashi, “Test-retest reproducibility of quantitative CBF measurements using FAIR perfusion MRI and acetazolamide challenge,” Magn. Reson. Med. 47(5), 921–928 (2002).
[CrossRef] [PubMed]

Neurocrit. Care (2)

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010).
[CrossRef] [PubMed]

Neuroimage (3)

N. Roche-Labarbe, F. Wallois, E. Ponchel, G. Kongolo, and R. Grebe, “Coupled oxygenation oscillation measured by NIRS and intermittent cerebral activation on EEG in premature infants,” Neuroimage 36(3), 718–727 (2007).
[CrossRef] [PubMed]

G. Strangman, M. A. Franceschini, and D. A. Boas, “Factors affecting the accuracy of near-infrared spectroscopy concentration calculations for focal changes in oxygenation parameters,” Neuroimage 18(4), 865–879 (2003).
[CrossRef] [PubMed]

J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001).
[CrossRef] [PubMed]

Neurology (1)

M. I. Chimowitz, A. J. Furlan, S. C. Jones, C. A. Sila, R. L. Lorig, L. Paranandi, and G. J. Beck, “Transcranial Doppler assessment of cerebral perfusion reserve in patients with carotid occlusive disease and no evidence of cerebral infarction,” Neurology 43(2), 353–357 (1993).
[PubMed]

Nucl. Med. (Stuttg.) (1)

T. Kreisig, P. Schmiedek, G. Leinsinger, K. Einhäupl, and E. Moser, “[133Xe-DSPECT: normal values of resting cerebral blood flow and reserve capacity],” Nucl. Med. (Stuttg.) 26(5), 192–197 (1987).
[PubMed]

Opt. Express (5)

V. Toronov, E. D’Amico, D. Hueber, E. Gratton, B. Barbieri, and A. Webb, “Optimization of the signal-to-noise ratio of frequency-domain instrumentation for near-infrared spectro-imaging of the human brain,” Opt. Express 11(21), 2717–2729 (2003).
[CrossRef] [PubMed]

L. Gagnon, M. Desjardins, J. Jehanne-Lacasse, L. Bherer, and F. Lesage, “Investigation of diffuse correlation spectroscopy in multi-layered media including the human head,” Opt. Express 16(20), 15514–15530 (2008).
[CrossRef] [PubMed]

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, “Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients,” Opt. Express 17(5), 3884–3902 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh, “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound,” Opt. Express 17(15), 12571–12581 (2009).
[CrossRef] [PubMed]

Opt. Lett. (1)

Phys. Med. Biol. (4)

D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003).
[CrossRef] [PubMed]

A. Torricelli, A. Pifferi, P. Taroni, E. Giambattistelli, and R. Cubeddu, “In vivo optical characterization of human tissues from 610 to 1010 nm by time-resolved reflectance spectroscopy,” Phys. Med. Biol. 46(8), 2227–2237 (2001).
[CrossRef] [PubMed]

S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys. Med. Biol. 37(7), 1531–1560 (1992).
[CrossRef] [PubMed]

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304 (1995).
[CrossRef] [PubMed]

Phys. Rev. Lett. (1)

D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and imaging with diffusing temporal field correlations,” Phys. Rev. Lett. 75(9), 1855–1858 (1995).
[CrossRef] [PubMed]

Physiol. Meas. (2)

S. Kohri, Y. Hoshi, M. Tamura, C. Kato, Y. Kuge, and N. Tamaki, “Quantitative evaluation of the relative contribution ratio of cerebral tissue to near-infrared signals in the adult human head: a preliminary study,” Physiol. Meas. 23(2), 301–312 (2002).
[CrossRef] [PubMed]

T. S. Leung, I. Tachtsidis, M. M. Tisdall, C. Pritchard, M. Smith, and C. E. Elwell, “Estimating a modified Grubb’s exponent in healthy human brains with near infrared spectroscopy and transcranial Doppler,” Physiol. Meas. 30(1), 1–12 (2009).
[CrossRef] [PubMed]

Physiol. Rev. (1)

N. A. Lassen, “Cerebral blood flow and oxygen consumption in man,” Physiol. Rev. 39(2), 183–238 (1959).
[PubMed]

Proc. Natl. Acad. Sci. U.S.A. (2)

T. L. Davis, K. K. Kwong, R. M. Weisskoff, and B. R. Rosen, “Calibrated functional MRI: mapping the dynamics of oxidative metabolism,” Proc. Natl. Acad. Sci. U.S.A. 95(4), 1834–1839 (1998).
[CrossRef] [PubMed]

R. D. Hoge, J. Atkinson, B. Gill, G. R. Crelier, S. Marrett, and G. B. Pike, “Linear coupling between cerebral blood flow and oxygen consumption in activated human cortex,” Proc. Natl. Acad. Sci. U.S.A. 96(16), 9403–9408 (1999).
[CrossRef] [PubMed]

Rep. Prog. Phys. (1)

T. Durduran, R. Choe, W. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010).
[CrossRef]

Stroke (14)

M. Kaminogo, A. Ichikura, S. Shibata, T. Toba, and M. Yonekura, “Effect of acetazolamide on regional cerebral oxygen saturation and regional cerebral blood flow,” Stroke 26(12), 2358–2360 (1995).
[PubMed]

G. I. Mchedlishvili, N. P. Mitagvaria, and L. G. Ormotsadze, “Vascular mechanisms controlling a constant blood supply to the brain (“autoregulation”),” Stroke 4(5), 742–750 (1973).
[PubMed]

B. Widder, B. Kleiser, and H. Krapf, “Course of cerebrovascular reactivity in patients with carotid artery occlusions,” Stroke 25(10), 1963–1967 (1994).
[PubMed]

A. Piepgras, P. Schmiedek, G. Leinsinger, R. L. Haberl, C. M. Kirsch, and K. M. Einhäupl, “A simple test to assess cerebrovascular reserve capacity using transcranial Doppler sonography and acetazolamide,” Stroke 21(9), 1306–1311 (1990).
[PubMed]

P. Démolis, G. Florence, L. Thomas, Y. R. Tran Dinh, J. F. Giudicelli, J. Seylaz, and N. J. Alkayed, “Is the acetazolamide test valid for quantitative assessment of maximal cerebral autoregulatory vasodilation? An experimental study,” Stroke 31(2), 508–515 (2000).
[PubMed]

U. Sabatini, P. Celsis, G. Viallard, A. Rascol, and J. P. Marc-Vergnes, “Quantitative assessment of cerebral blood volume by single-photon emission computed tomography,” Stroke 22(3), 324–330 (1991).
[PubMed]

M. Matteis, E. Troisi, B. C. Monaldo, C. Caltagirone, and M. Silvestrini, “Age and sex differences in cerebral hemodynamics: a transcranial Doppler study,” Stroke 29(5), 963–967 (1998).
[PubMed]

B. M. Eicke, E. Buss, R. R. Bähr, G. Hajak, and W. Paulus, “Influence of acetazolamide and CO2 on extracranial flow volume and intracranial blood flow velocity,” Stroke 30(1), 76–80 (1999).
[PubMed]

H. A. Kontos, “Validity of cerebral arterial blood flow calculations from velocity measurements,” Stroke 20(1), 1–3 (1989).
[PubMed]

R. Cote, H. J. Barnett, and D. W. Taylor, “Internal carotid occlusion: a prospective study,” Stroke 14(6), 898–902 (1983).
[PubMed]

S. Durham, H. Smith, M. Rutigliano, and H. Yonas, “Assessment of cerebral vasoreactivity and stroke risk using Xe-CT acetazolamide challenge,” Stroke 22, 138 (1991).

R. L. Grubb, M. E. Raichle, J. O. Eichling, and M. M. Ter-Pogossian, “The effects of changes in PaCO2 on cerebral blood volume, blood flow, and vascular mean transit time,” Stroke 5(5), 630–639 (1974).
[PubMed]

A. Dahl, K. F. Lindegaard, D. Russell, R. Nyberg-Hansen, K. Rootwelt, W. Sorteberg, and H. Nornes, “A comparison of transcranial Doppler and cerebral blood flow studies to assess cerebral vasoreactivity,” Stroke 23(1), 15–19 (1992).
[PubMed]

B. Kleiser and B. Widder, “Course of carotid artery occlusions with impaired cerebrovascular reactivity,” Stroke 23(2), 171–174 (1992).
[PubMed]

Surg. Neurol. (1)

R. Roski, R. F. Spetzler, M. Owen, K. Chandar, J. G. Sholl, and F. E. Nulsen, “Reversal of seven-year old visual field defect with extracranial-intracranial arterial anastomosis,” Surg. Neurol. 10(4), 267–268 (1978).
[PubMed]

Trends Neurosci. (1)

A. Villringer and B. Chance, “Non-invasive optical spectroscopy and imaging of human brain function,” Trends Neurosci. 20(10), 435–442 (1997).
[CrossRef] [PubMed]

Other (2)

K. Hornik, “The R FAQ,” (2010). ISBN 3–900051–08–9.

I. Tachtsidis, T. Leung, D. Delpy, C. Elwell, M. Tisdall, and M. Smith, “Cerebral blood flow assessment with indocyanine green bolus transit detection by near-infrared spectroscopy before and after acetazolamide challenge in humans,” Biomedical Optics (2006).

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (3)

Fig. 1.
Fig. 1.

(a) The time line of the study protocol. (b) A schematic representation of the placement of optical and ultrasound probes.

Fig. 2.
Fig. 2.

Average data for all studied subjects (8 male, 2 female, mean age 30.6) showing (a) the oxy- and deoxy-hemoglobin changes due to ACZ administration (NIRS data);(b) hemodynamic response to ACZ observed by changes in CBF measured by DCS and CBFV measured by TCD; and (c) changes in rCMRO 2 calculated point-by-point from changes in oxy- and deoxy-hemoglobin and rCBF. Vertical bold lines show the start of the baseline, start of injection, end of injection, and end of the measurement respectively. The data between the vertical dashed line and the end of the measurement have been averaged and used for further analysis. The error bars show the standard-deviation values at about 1.5 minute intervals.

Fig. 3.
Fig. 3.

Box-plots summarizing the changes of: (a) oxy- and deoxy-hemoglobin concentrations; (b) rCBF (DCS) and rCBFV (TCD); and (c) rCMRO 2, compared to the baseline after ACZ injection. Here, L:left and R:right.

Tables (1)

Tables Icon

Table 1. Mean (± standard-deviation, STD) and p-values for optical and ultrasound data. Superscript, *, implies that observed change is statistically significant (p<0.05)

Equations (2)

Equations on this page are rendered with MathJax. Learn more.

rCMRO 2 = ( Δ CMRO 2 + CMRO 2 , bl CMRO 2 , bl ) = ( 1 + γ r Δ Hb Hb bl ) × ( 1 + γ t Δ THC THC bl ) 1
× ( rCBF )

Metrics