Abstract

In this work, we incorporate and image individual fluorescent nanodiamonds in the powerful genetic model system Drosophila melanogaster. Fluorescence correlation spectroscopy and wide-field imaging techniques are applied to individual fluorescent nanodiamonds in blastoderm cells during stage 5 of development, up to a depth of 40 µm. The majority of nanodiamonds in the blastoderm cells during cellularization exhibit free diffusion with an average diffusion coefficient of (6 ± 3) × 10−3 µm2/s, (mean ± SD). Driven motion in the blastoderm cells was also observed with an average velocity of 0.13 ± 0.10 µm/s (mean ± SD) µm/s and an average applied force of 0.07 ± 0.05 pN (mean ± SD). Nanodiamonds in the periplasm between the nuclei and yolk were also found to undergo free diffusion with a significantly larger diffusion coefficient of (63 ± 35) × 10−3 µm2/s (mean ± SD). Driven motion in this region exhibited similar average velocities and applied forces compared to the blastoderm cells indicating the transport dynamics in the two cytoplasmic regions are analogous.

© 2014 Optical Society of America

Full Article  |  PDF Article

References

  • View by:
  • |
  • |
  • |

  1. K. Visscher, M. J. Schnitzer, and S. M. Block, “Single kinesin molecules studied with a molecular force clamp,” Nature400(6740), 184–189 (1999).
    [CrossRef] [PubMed]
  2. M. P. Sheetz and J. A. Spudich, “Movement of myosin-coated fluorescent beads on actin cables in vitro,” Nature303(5912), 31–35 (1983).
    [CrossRef] [PubMed]
  3. C. Kural, H. Kim, S. Syed, G. Goshima, V. I. Gelfand, and P. R. Selvin, “Kinesin and Dynein Move a Peroxisome in Vivo: A Tug-of-War or Coordinated Movement?” Science308(5727), 1469–1472 (2005).
    [CrossRef] [PubMed]
  4. J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
    [CrossRef] [PubMed]
  5. X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, and S. Weiss, “Quantum dots for live cells, in vivo imaging, and diagnostics,” Science307(5709), 538–544 (2005).
    [CrossRef] [PubMed]
  6. M. J. Saxton and K. Jacobson, “Single-particle tracking: Applications to Membrane Dynamics,” Annu. Rev. Biophys. Biomol. Struct.26(1), 373–399 (1997).
    [CrossRef] [PubMed]
  7. C. C. Fu, H. Y. Lee, K. Chen, T. S. Lim, H. Y. Wu, P. K. Lin, P. K. Wei, P. H. Tsao, H. C. Chang, and W. Fann, “Characterization and application of single fluorescent nanodiamonds as cellular biomarkers,” Proc. Natl. Acad. Sci. U.S.A.104(3), 727–732 (2007).
    [CrossRef] [PubMed]
  8. O. Faklaris, D. Garrot, V. Joshi, F. Druon, J. P. Boudou, T. Sauvage, P. Georges, P. A. Curmi, and F. Treussart, “Detection of single photoluminescent diamond nanoparticles in cells and study of the internalization pathway,” Small4(12), 2236–2239 (2008).
    [CrossRef] [PubMed]
  9. O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J. C. Arnault, A. Thorel, J. P. Boudou, P. A. Curmi, and F. Treussart, “Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells,” ACS Nano3(12), 3955–3962 (2009).
    [CrossRef] [PubMed]
  10. Y. R. Chang, H. Y. Lee, K. Chen, C. C. Chang, D. S. Tsai, C. C. Fu, T. S. Lim, Y. K. Tzeng, C. Y. Fang, C. C. Han, H. C. Chang, and W. Fann, “Mass production and dynamic imaging of fluorescent nanodiamonds,” Nat. Nanotechnol.3(5), 284–288 (2008).
    [CrossRef] [PubMed]
  11. L. P. McGuinness, Y. Yan, A. Stacey, D. A. Simpson, L. T. Hall, D. Maclaurin, S. Prawer, P. Mulvaney, J. Wrachtrup, F. Caruso, R. E. Scholten, and L. C. L. Hollenberg, “Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells,” Nat. Nanotechnol.6(6), 358–363 (2011).
    [CrossRef] [PubMed]
  12. N. Mohan, C.-S. Chen, H.-H. Hsieh, Y.-C. Wu, and H.-C. Chang, “In Vivo Imaging and Toxicity Assessments of Fluorescent Nanodiamonds in Caenorhabditis elegans,” Nano Lett.10(9), 3692–3699 (2010).
    [CrossRef] [PubMed]
  13. V. Vaijayanthimala, P.-Y. Cheng, S.-H. Yeh, K.-K. Liu, C.-H. Hsiao, J.-I. Chao, and H.-C. Chang, “The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent,” Biomaterials33(31), 7794–7802 (2012).
    [CrossRef] [PubMed]
  14. Y. Kuo, T.-Y. Hsu, Y.-C. Wu, and H.-C. Chang, “Fluorescent nanodiamond as a probe for the intercellular transport of proteins in vivo,” Biomaterials34(33), 8352–8360 (2013).
    [CrossRef] [PubMed]
  15. R. Igarashi, Y. Yoshinari, H. Yokota, T. Sugi, F. Sugihara, K. Ikeda, H. Sumiya, S. Tsuji, I. Mori, H. Tochio, Y. Harada, and M. Shirakawa, “Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo,” Nano Lett.12(11), 5726–5732 (2012).
    [CrossRef] [PubMed]
  16. J. M. Crawford, N. Harden, T. Leung, L. Lim, and D. P. Kiehart, “Cellularization in Drosophila melanogaster Is Disrupted by the Inhibition of Rho Activity and the Activation of Cdc42 Function,” Dev. Biol.204(1), 151–164 (1998).
    [CrossRef] [PubMed]
  17. A. M. Sokac and E. Wieschaus, “Local actin-dependent endocytosis is zygotically controlled to initiate Drosophila cellularization,” Dev. Cell14(5), 775–786 (2008).
    [CrossRef] [PubMed]
  18. A. Royou, C. Field, J. C. Sisson, W. Sullivan, and R. Karess, “Reassessing the role and dynamics of nonmuscle myosin II during furrow formation in early Drosophila embryos,” Mol. Biol. Cell15(2), 838–850 (2003).
    [CrossRef] [PubMed]
  19. T. Lecuit, “Junctions and vesicular trafficking during Drosophila cellularization,” J. Cell Sci.117(16), 3427–3433 (2004).
    [CrossRef] [PubMed]
  20. A. Mazumdar and M. Mazumdar, “How one becomes many: blastoderm cellularization in Drosophila melanogaster,” Bioessays24(11), 1012–1022 (2002).
    [CrossRef] [PubMed]
  21. O. Krichevsky and G. Bonnet, “Fluorescence correlation spectroscopy: the technique and its applications,” Rep. Prog. Phys.65(2), 251–297 (2002).
    [CrossRef]
  22. R. Mallik, B. C. Carter, S. A. Lex, S. J. King, and S. P. Gross, “Cytoplasmic dynein functions as a gear in response to load,” Nature427(6975), 649–652 (2004).
    [CrossRef] [PubMed]
  23. R. M. Mazo, Brownian Motion: Fluctuations, Dynamics, and Applications (Clarendon press Oxford, 2002).
  24. M. P. Sheetz and J. A. Spudich, “Movement of myosin-coated fluorescent beads on actin cables in vitro,” Nature303, 31–35 (1983).
  25. E. H. Chen, O. Gaathon, M. E. Trusheim, and D. Englund, “Wide-Field Multispectral Super-Resolution Imaging Using Spin-Dependent Fluorescence in Nanodiamonds,” Nano Lett.13(5), 2073–2077 (2013).
    [CrossRef] [PubMed]

2013 (2)

Y. Kuo, T.-Y. Hsu, Y.-C. Wu, and H.-C. Chang, “Fluorescent nanodiamond as a probe for the intercellular transport of proteins in vivo,” Biomaterials34(33), 8352–8360 (2013).
[CrossRef] [PubMed]

E. H. Chen, O. Gaathon, M. E. Trusheim, and D. Englund, “Wide-Field Multispectral Super-Resolution Imaging Using Spin-Dependent Fluorescence in Nanodiamonds,” Nano Lett.13(5), 2073–2077 (2013).
[CrossRef] [PubMed]

2012 (2)

R. Igarashi, Y. Yoshinari, H. Yokota, T. Sugi, F. Sugihara, K. Ikeda, H. Sumiya, S. Tsuji, I. Mori, H. Tochio, Y. Harada, and M. Shirakawa, “Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo,” Nano Lett.12(11), 5726–5732 (2012).
[CrossRef] [PubMed]

V. Vaijayanthimala, P.-Y. Cheng, S.-H. Yeh, K.-K. Liu, C.-H. Hsiao, J.-I. Chao, and H.-C. Chang, “The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent,” Biomaterials33(31), 7794–7802 (2012).
[CrossRef] [PubMed]

2011 (1)

L. P. McGuinness, Y. Yan, A. Stacey, D. A. Simpson, L. T. Hall, D. Maclaurin, S. Prawer, P. Mulvaney, J. Wrachtrup, F. Caruso, R. E. Scholten, and L. C. L. Hollenberg, “Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells,” Nat. Nanotechnol.6(6), 358–363 (2011).
[CrossRef] [PubMed]

2010 (1)

N. Mohan, C.-S. Chen, H.-H. Hsieh, Y.-C. Wu, and H.-C. Chang, “In Vivo Imaging and Toxicity Assessments of Fluorescent Nanodiamonds in Caenorhabditis elegans,” Nano Lett.10(9), 3692–3699 (2010).
[CrossRef] [PubMed]

2009 (2)

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J. C. Arnault, A. Thorel, J. P. Boudou, P. A. Curmi, and F. Treussart, “Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells,” ACS Nano3(12), 3955–3962 (2009).
[CrossRef] [PubMed]

2008 (3)

Y. R. Chang, H. Y. Lee, K. Chen, C. C. Chang, D. S. Tsai, C. C. Fu, T. S. Lim, Y. K. Tzeng, C. Y. Fang, C. C. Han, H. C. Chang, and W. Fann, “Mass production and dynamic imaging of fluorescent nanodiamonds,” Nat. Nanotechnol.3(5), 284–288 (2008).
[CrossRef] [PubMed]

O. Faklaris, D. Garrot, V. Joshi, F. Druon, J. P. Boudou, T. Sauvage, P. Georges, P. A. Curmi, and F. Treussart, “Detection of single photoluminescent diamond nanoparticles in cells and study of the internalization pathway,” Small4(12), 2236–2239 (2008).
[CrossRef] [PubMed]

A. M. Sokac and E. Wieschaus, “Local actin-dependent endocytosis is zygotically controlled to initiate Drosophila cellularization,” Dev. Cell14(5), 775–786 (2008).
[CrossRef] [PubMed]

2007 (1)

C. C. Fu, H. Y. Lee, K. Chen, T. S. Lim, H. Y. Wu, P. K. Lin, P. K. Wei, P. H. Tsao, H. C. Chang, and W. Fann, “Characterization and application of single fluorescent nanodiamonds as cellular biomarkers,” Proc. Natl. Acad. Sci. U.S.A.104(3), 727–732 (2007).
[CrossRef] [PubMed]

2005 (2)

C. Kural, H. Kim, S. Syed, G. Goshima, V. I. Gelfand, and P. R. Selvin, “Kinesin and Dynein Move a Peroxisome in Vivo: A Tug-of-War or Coordinated Movement?” Science308(5727), 1469–1472 (2005).
[CrossRef] [PubMed]

X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, and S. Weiss, “Quantum dots for live cells, in vivo imaging, and diagnostics,” Science307(5709), 538–544 (2005).
[CrossRef] [PubMed]

2004 (2)

T. Lecuit, “Junctions and vesicular trafficking during Drosophila cellularization,” J. Cell Sci.117(16), 3427–3433 (2004).
[CrossRef] [PubMed]

R. Mallik, B. C. Carter, S. A. Lex, S. J. King, and S. P. Gross, “Cytoplasmic dynein functions as a gear in response to load,” Nature427(6975), 649–652 (2004).
[CrossRef] [PubMed]

2003 (1)

A. Royou, C. Field, J. C. Sisson, W. Sullivan, and R. Karess, “Reassessing the role and dynamics of nonmuscle myosin II during furrow formation in early Drosophila embryos,” Mol. Biol. Cell15(2), 838–850 (2003).
[CrossRef] [PubMed]

2002 (2)

A. Mazumdar and M. Mazumdar, “How one becomes many: blastoderm cellularization in Drosophila melanogaster,” Bioessays24(11), 1012–1022 (2002).
[CrossRef] [PubMed]

O. Krichevsky and G. Bonnet, “Fluorescence correlation spectroscopy: the technique and its applications,” Rep. Prog. Phys.65(2), 251–297 (2002).
[CrossRef]

1999 (1)

K. Visscher, M. J. Schnitzer, and S. M. Block, “Single kinesin molecules studied with a molecular force clamp,” Nature400(6740), 184–189 (1999).
[CrossRef] [PubMed]

1998 (1)

J. M. Crawford, N. Harden, T. Leung, L. Lim, and D. P. Kiehart, “Cellularization in Drosophila melanogaster Is Disrupted by the Inhibition of Rho Activity and the Activation of Cdc42 Function,” Dev. Biol.204(1), 151–164 (1998).
[CrossRef] [PubMed]

1997 (1)

M. J. Saxton and K. Jacobson, “Single-particle tracking: Applications to Membrane Dynamics,” Annu. Rev. Biophys. Biomol. Struct.26(1), 373–399 (1997).
[CrossRef] [PubMed]

1983 (2)

M. P. Sheetz and J. A. Spudich, “Movement of myosin-coated fluorescent beads on actin cables in vitro,” Nature303(5912), 31–35 (1983).
[CrossRef] [PubMed]

M. P. Sheetz and J. A. Spudich, “Movement of myosin-coated fluorescent beads on actin cables in vitro,” Nature303, 31–35 (1983).

Arnault, J. C.

O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J. C. Arnault, A. Thorel, J. P. Boudou, P. A. Curmi, and F. Treussart, “Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells,” ACS Nano3(12), 3955–3962 (2009).
[CrossRef] [PubMed]

Baybayan, P.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Bentolila, L. A.

X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, and S. Weiss, “Quantum dots for live cells, in vivo imaging, and diagnostics,” Science307(5709), 538–544 (2005).
[CrossRef] [PubMed]

Bettman, B.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Bibillo, A.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Bjornson, K.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Block, S. M.

K. Visscher, M. J. Schnitzer, and S. M. Block, “Single kinesin molecules studied with a molecular force clamp,” Nature400(6740), 184–189 (1999).
[CrossRef] [PubMed]

Bonnet, G.

O. Krichevsky and G. Bonnet, “Fluorescence correlation spectroscopy: the technique and its applications,” Rep. Prog. Phys.65(2), 251–297 (2002).
[CrossRef]

Boudou, J. P.

O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J. C. Arnault, A. Thorel, J. P. Boudou, P. A. Curmi, and F. Treussart, “Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells,” ACS Nano3(12), 3955–3962 (2009).
[CrossRef] [PubMed]

O. Faklaris, D. Garrot, V. Joshi, F. Druon, J. P. Boudou, T. Sauvage, P. Georges, P. A. Curmi, and F. Treussart, “Detection of single photoluminescent diamond nanoparticles in cells and study of the internalization pathway,” Small4(12), 2236–2239 (2008).
[CrossRef] [PubMed]

Carter, B. C.

R. Mallik, B. C. Carter, S. A. Lex, S. J. King, and S. P. Gross, “Cytoplasmic dynein functions as a gear in response to load,” Nature427(6975), 649–652 (2004).
[CrossRef] [PubMed]

Caruso, F.

L. P. McGuinness, Y. Yan, A. Stacey, D. A. Simpson, L. T. Hall, D. Maclaurin, S. Prawer, P. Mulvaney, J. Wrachtrup, F. Caruso, R. E. Scholten, and L. C. L. Hollenberg, “Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells,” Nat. Nanotechnol.6(6), 358–363 (2011).
[CrossRef] [PubMed]

Chang, C. C.

Y. R. Chang, H. Y. Lee, K. Chen, C. C. Chang, D. S. Tsai, C. C. Fu, T. S. Lim, Y. K. Tzeng, C. Y. Fang, C. C. Han, H. C. Chang, and W. Fann, “Mass production and dynamic imaging of fluorescent nanodiamonds,” Nat. Nanotechnol.3(5), 284–288 (2008).
[CrossRef] [PubMed]

Chang, H. C.

Y. R. Chang, H. Y. Lee, K. Chen, C. C. Chang, D. S. Tsai, C. C. Fu, T. S. Lim, Y. K. Tzeng, C. Y. Fang, C. C. Han, H. C. Chang, and W. Fann, “Mass production and dynamic imaging of fluorescent nanodiamonds,” Nat. Nanotechnol.3(5), 284–288 (2008).
[CrossRef] [PubMed]

C. C. Fu, H. Y. Lee, K. Chen, T. S. Lim, H. Y. Wu, P. K. Lin, P. K. Wei, P. H. Tsao, H. C. Chang, and W. Fann, “Characterization and application of single fluorescent nanodiamonds as cellular biomarkers,” Proc. Natl. Acad. Sci. U.S.A.104(3), 727–732 (2007).
[CrossRef] [PubMed]

Chang, H.-C.

Y. Kuo, T.-Y. Hsu, Y.-C. Wu, and H.-C. Chang, “Fluorescent nanodiamond as a probe for the intercellular transport of proteins in vivo,” Biomaterials34(33), 8352–8360 (2013).
[CrossRef] [PubMed]

V. Vaijayanthimala, P.-Y. Cheng, S.-H. Yeh, K.-K. Liu, C.-H. Hsiao, J.-I. Chao, and H.-C. Chang, “The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent,” Biomaterials33(31), 7794–7802 (2012).
[CrossRef] [PubMed]

N. Mohan, C.-S. Chen, H.-H. Hsieh, Y.-C. Wu, and H.-C. Chang, “In Vivo Imaging and Toxicity Assessments of Fluorescent Nanodiamonds in Caenorhabditis elegans,” Nano Lett.10(9), 3692–3699 (2010).
[CrossRef] [PubMed]

Chang, Y. R.

Y. R. Chang, H. Y. Lee, K. Chen, C. C. Chang, D. S. Tsai, C. C. Fu, T. S. Lim, Y. K. Tzeng, C. Y. Fang, C. C. Han, H. C. Chang, and W. Fann, “Mass production and dynamic imaging of fluorescent nanodiamonds,” Nat. Nanotechnol.3(5), 284–288 (2008).
[CrossRef] [PubMed]

Chao, J.-I.

V. Vaijayanthimala, P.-Y. Cheng, S.-H. Yeh, K.-K. Liu, C.-H. Hsiao, J.-I. Chao, and H.-C. Chang, “The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent,” Biomaterials33(31), 7794–7802 (2012).
[CrossRef] [PubMed]

Chaudhuri, B.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Chen, C.-S.

N. Mohan, C.-S. Chen, H.-H. Hsieh, Y.-C. Wu, and H.-C. Chang, “In Vivo Imaging and Toxicity Assessments of Fluorescent Nanodiamonds in Caenorhabditis elegans,” Nano Lett.10(9), 3692–3699 (2010).
[CrossRef] [PubMed]

Chen, E. H.

E. H. Chen, O. Gaathon, M. E. Trusheim, and D. Englund, “Wide-Field Multispectral Super-Resolution Imaging Using Spin-Dependent Fluorescence in Nanodiamonds,” Nano Lett.13(5), 2073–2077 (2013).
[CrossRef] [PubMed]

Chen, K.

Y. R. Chang, H. Y. Lee, K. Chen, C. C. Chang, D. S. Tsai, C. C. Fu, T. S. Lim, Y. K. Tzeng, C. Y. Fang, C. C. Han, H. C. Chang, and W. Fann, “Mass production and dynamic imaging of fluorescent nanodiamonds,” Nat. Nanotechnol.3(5), 284–288 (2008).
[CrossRef] [PubMed]

C. C. Fu, H. Y. Lee, K. Chen, T. S. Lim, H. Y. Wu, P. K. Lin, P. K. Wei, P. H. Tsao, H. C. Chang, and W. Fann, “Characterization and application of single fluorescent nanodiamonds as cellular biomarkers,” Proc. Natl. Acad. Sci. U.S.A.104(3), 727–732 (2007).
[CrossRef] [PubMed]

Cheng, P.-Y.

V. Vaijayanthimala, P.-Y. Cheng, S.-H. Yeh, K.-K. Liu, C.-H. Hsiao, J.-I. Chao, and H.-C. Chang, “The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent,” Biomaterials33(31), 7794–7802 (2012).
[CrossRef] [PubMed]

Christians, F.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Cicero, R.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Clark, S.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Crawford, J. M.

J. M. Crawford, N. Harden, T. Leung, L. Lim, and D. P. Kiehart, “Cellularization in Drosophila melanogaster Is Disrupted by the Inhibition of Rho Activity and the Activation of Cdc42 Function,” Dev. Biol.204(1), 151–164 (1998).
[CrossRef] [PubMed]

Curmi, P. A.

O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J. C. Arnault, A. Thorel, J. P. Boudou, P. A. Curmi, and F. Treussart, “Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells,” ACS Nano3(12), 3955–3962 (2009).
[CrossRef] [PubMed]

O. Faklaris, D. Garrot, V. Joshi, F. Druon, J. P. Boudou, T. Sauvage, P. Georges, P. A. Curmi, and F. Treussart, “Detection of single photoluminescent diamond nanoparticles in cells and study of the internalization pathway,” Small4(12), 2236–2239 (2008).
[CrossRef] [PubMed]

Dalal, R.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Dewinter, A.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Dixon, J.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Doose, S.

X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, and S. Weiss, “Quantum dots for live cells, in vivo imaging, and diagnostics,” Science307(5709), 538–544 (2005).
[CrossRef] [PubMed]

Druon, F.

O. Faklaris, D. Garrot, V. Joshi, F. Druon, J. P. Boudou, T. Sauvage, P. Georges, P. A. Curmi, and F. Treussart, “Detection of single photoluminescent diamond nanoparticles in cells and study of the internalization pathway,” Small4(12), 2236–2239 (2008).
[CrossRef] [PubMed]

Eid, J.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Englund, D.

E. H. Chen, O. Gaathon, M. E. Trusheim, and D. Englund, “Wide-Field Multispectral Super-Resolution Imaging Using Spin-Dependent Fluorescence in Nanodiamonds,” Nano Lett.13(5), 2073–2077 (2013).
[CrossRef] [PubMed]

Faklaris, O.

O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J. C. Arnault, A. Thorel, J. P. Boudou, P. A. Curmi, and F. Treussart, “Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells,” ACS Nano3(12), 3955–3962 (2009).
[CrossRef] [PubMed]

O. Faklaris, D. Garrot, V. Joshi, F. Druon, J. P. Boudou, T. Sauvage, P. Georges, P. A. Curmi, and F. Treussart, “Detection of single photoluminescent diamond nanoparticles in cells and study of the internalization pathway,” Small4(12), 2236–2239 (2008).
[CrossRef] [PubMed]

Fang, C. Y.

Y. R. Chang, H. Y. Lee, K. Chen, C. C. Chang, D. S. Tsai, C. C. Fu, T. S. Lim, Y. K. Tzeng, C. Y. Fang, C. C. Han, H. C. Chang, and W. Fann, “Mass production and dynamic imaging of fluorescent nanodiamonds,” Nat. Nanotechnol.3(5), 284–288 (2008).
[CrossRef] [PubMed]

Fann, W.

Y. R. Chang, H. Y. Lee, K. Chen, C. C. Chang, D. S. Tsai, C. C. Fu, T. S. Lim, Y. K. Tzeng, C. Y. Fang, C. C. Han, H. C. Chang, and W. Fann, “Mass production and dynamic imaging of fluorescent nanodiamonds,” Nat. Nanotechnol.3(5), 284–288 (2008).
[CrossRef] [PubMed]

C. C. Fu, H. Y. Lee, K. Chen, T. S. Lim, H. Y. Wu, P. K. Lin, P. K. Wei, P. H. Tsao, H. C. Chang, and W. Fann, “Characterization and application of single fluorescent nanodiamonds as cellular biomarkers,” Proc. Natl. Acad. Sci. U.S.A.104(3), 727–732 (2007).
[CrossRef] [PubMed]

Fehr, A.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Field, C.

A. Royou, C. Field, J. C. Sisson, W. Sullivan, and R. Karess, “Reassessing the role and dynamics of nonmuscle myosin II during furrow formation in early Drosophila embryos,” Mol. Biol. Cell15(2), 838–850 (2003).
[CrossRef] [PubMed]

Foquet, M.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Fu, C. C.

Y. R. Chang, H. Y. Lee, K. Chen, C. C. Chang, D. S. Tsai, C. C. Fu, T. S. Lim, Y. K. Tzeng, C. Y. Fang, C. C. Han, H. C. Chang, and W. Fann, “Mass production and dynamic imaging of fluorescent nanodiamonds,” Nat. Nanotechnol.3(5), 284–288 (2008).
[CrossRef] [PubMed]

C. C. Fu, H. Y. Lee, K. Chen, T. S. Lim, H. Y. Wu, P. K. Lin, P. K. Wei, P. H. Tsao, H. C. Chang, and W. Fann, “Characterization and application of single fluorescent nanodiamonds as cellular biomarkers,” Proc. Natl. Acad. Sci. U.S.A.104(3), 727–732 (2007).
[CrossRef] [PubMed]

Gaathon, O.

E. H. Chen, O. Gaathon, M. E. Trusheim, and D. Englund, “Wide-Field Multispectral Super-Resolution Imaging Using Spin-Dependent Fluorescence in Nanodiamonds,” Nano Lett.13(5), 2073–2077 (2013).
[CrossRef] [PubMed]

Gaertner, A.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Gambhir, S. S.

X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, and S. Weiss, “Quantum dots for live cells, in vivo imaging, and diagnostics,” Science307(5709), 538–544 (2005).
[CrossRef] [PubMed]

Garrot, D.

O. Faklaris, D. Garrot, V. Joshi, F. Druon, J. P. Boudou, T. Sauvage, P. Georges, P. A. Curmi, and F. Treussart, “Detection of single photoluminescent diamond nanoparticles in cells and study of the internalization pathway,” Small4(12), 2236–2239 (2008).
[CrossRef] [PubMed]

Gelfand, V. I.

C. Kural, H. Kim, S. Syed, G. Goshima, V. I. Gelfand, and P. R. Selvin, “Kinesin and Dynein Move a Peroxisome in Vivo: A Tug-of-War or Coordinated Movement?” Science308(5727), 1469–1472 (2005).
[CrossRef] [PubMed]

Georges, P.

O. Faklaris, D. Garrot, V. Joshi, F. Druon, J. P. Boudou, T. Sauvage, P. Georges, P. A. Curmi, and F. Treussart, “Detection of single photoluminescent diamond nanoparticles in cells and study of the internalization pathway,” Small4(12), 2236–2239 (2008).
[CrossRef] [PubMed]

Gesset, C.

O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J. C. Arnault, A. Thorel, J. P. Boudou, P. A. Curmi, and F. Treussart, “Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells,” ACS Nano3(12), 3955–3962 (2009).
[CrossRef] [PubMed]

Girard, H.

O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J. C. Arnault, A. Thorel, J. P. Boudou, P. A. Curmi, and F. Treussart, “Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells,” ACS Nano3(12), 3955–3962 (2009).
[CrossRef] [PubMed]

Goshima, G.

C. Kural, H. Kim, S. Syed, G. Goshima, V. I. Gelfand, and P. R. Selvin, “Kinesin and Dynein Move a Peroxisome in Vivo: A Tug-of-War or Coordinated Movement?” Science308(5727), 1469–1472 (2005).
[CrossRef] [PubMed]

Gray, J.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Gross, S. P.

R. Mallik, B. C. Carter, S. A. Lex, S. J. King, and S. P. Gross, “Cytoplasmic dynein functions as a gear in response to load,” Nature427(6975), 649–652 (2004).
[CrossRef] [PubMed]

Hall, L. T.

L. P. McGuinness, Y. Yan, A. Stacey, D. A. Simpson, L. T. Hall, D. Maclaurin, S. Prawer, P. Mulvaney, J. Wrachtrup, F. Caruso, R. E. Scholten, and L. C. L. Hollenberg, “Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells,” Nat. Nanotechnol.6(6), 358–363 (2011).
[CrossRef] [PubMed]

Han, C. C.

Y. R. Chang, H. Y. Lee, K. Chen, C. C. Chang, D. S. Tsai, C. C. Fu, T. S. Lim, Y. K. Tzeng, C. Y. Fang, C. C. Han, H. C. Chang, and W. Fann, “Mass production and dynamic imaging of fluorescent nanodiamonds,” Nat. Nanotechnol.3(5), 284–288 (2008).
[CrossRef] [PubMed]

Harada, Y.

R. Igarashi, Y. Yoshinari, H. Yokota, T. Sugi, F. Sugihara, K. Ikeda, H. Sumiya, S. Tsuji, I. Mori, H. Tochio, Y. Harada, and M. Shirakawa, “Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo,” Nano Lett.12(11), 5726–5732 (2012).
[CrossRef] [PubMed]

Harden, N.

J. M. Crawford, N. Harden, T. Leung, L. Lim, and D. P. Kiehart, “Cellularization in Drosophila melanogaster Is Disrupted by the Inhibition of Rho Activity and the Activation of Cdc42 Function,” Dev. Biol.204(1), 151–164 (1998).
[CrossRef] [PubMed]

Hardenbol, P.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Heiner, C.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Hester, K.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Holden, D.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Hollenberg, L. C. L.

L. P. McGuinness, Y. Yan, A. Stacey, D. A. Simpson, L. T. Hall, D. Maclaurin, S. Prawer, P. Mulvaney, J. Wrachtrup, F. Caruso, R. E. Scholten, and L. C. L. Hollenberg, “Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells,” Nat. Nanotechnol.6(6), 358–363 (2011).
[CrossRef] [PubMed]

Hsiao, C.-H.

V. Vaijayanthimala, P.-Y. Cheng, S.-H. Yeh, K.-K. Liu, C.-H. Hsiao, J.-I. Chao, and H.-C. Chang, “The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent,” Biomaterials33(31), 7794–7802 (2012).
[CrossRef] [PubMed]

Hsieh, H.-H.

N. Mohan, C.-S. Chen, H.-H. Hsieh, Y.-C. Wu, and H.-C. Chang, “In Vivo Imaging and Toxicity Assessments of Fluorescent Nanodiamonds in Caenorhabditis elegans,” Nano Lett.10(9), 3692–3699 (2010).
[CrossRef] [PubMed]

Hsu, T.-Y.

Y. Kuo, T.-Y. Hsu, Y.-C. Wu, and H.-C. Chang, “Fluorescent nanodiamond as a probe for the intercellular transport of proteins in vivo,” Biomaterials34(33), 8352–8360 (2013).
[CrossRef] [PubMed]

Igarashi, R.

R. Igarashi, Y. Yoshinari, H. Yokota, T. Sugi, F. Sugihara, K. Ikeda, H. Sumiya, S. Tsuji, I. Mori, H. Tochio, Y. Harada, and M. Shirakawa, “Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo,” Nano Lett.12(11), 5726–5732 (2012).
[CrossRef] [PubMed]

Ikeda, K.

R. Igarashi, Y. Yoshinari, H. Yokota, T. Sugi, F. Sugihara, K. Ikeda, H. Sumiya, S. Tsuji, I. Mori, H. Tochio, Y. Harada, and M. Shirakawa, “Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo,” Nano Lett.12(11), 5726–5732 (2012).
[CrossRef] [PubMed]

Irinopoulou, T.

O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J. C. Arnault, A. Thorel, J. P. Boudou, P. A. Curmi, and F. Treussart, “Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells,” ACS Nano3(12), 3955–3962 (2009).
[CrossRef] [PubMed]

Jacobson, K.

M. J. Saxton and K. Jacobson, “Single-particle tracking: Applications to Membrane Dynamics,” Annu. Rev. Biophys. Biomol. Struct.26(1), 373–399 (1997).
[CrossRef] [PubMed]

Joshi, V.

O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J. C. Arnault, A. Thorel, J. P. Boudou, P. A. Curmi, and F. Treussart, “Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells,” ACS Nano3(12), 3955–3962 (2009).
[CrossRef] [PubMed]

O. Faklaris, D. Garrot, V. Joshi, F. Druon, J. P. Boudou, T. Sauvage, P. Georges, P. A. Curmi, and F. Treussart, “Detection of single photoluminescent diamond nanoparticles in cells and study of the internalization pathway,” Small4(12), 2236–2239 (2008).
[CrossRef] [PubMed]

Karess, R.

A. Royou, C. Field, J. C. Sisson, W. Sullivan, and R. Karess, “Reassessing the role and dynamics of nonmuscle myosin II during furrow formation in early Drosophila embryos,” Mol. Biol. Cell15(2), 838–850 (2003).
[CrossRef] [PubMed]

Kearns, G.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Kiehart, D. P.

J. M. Crawford, N. Harden, T. Leung, L. Lim, and D. P. Kiehart, “Cellularization in Drosophila melanogaster Is Disrupted by the Inhibition of Rho Activity and the Activation of Cdc42 Function,” Dev. Biol.204(1), 151–164 (1998).
[CrossRef] [PubMed]

Kim, H.

C. Kural, H. Kim, S. Syed, G. Goshima, V. I. Gelfand, and P. R. Selvin, “Kinesin and Dynein Move a Peroxisome in Vivo: A Tug-of-War or Coordinated Movement?” Science308(5727), 1469–1472 (2005).
[CrossRef] [PubMed]

King, S. J.

R. Mallik, B. C. Carter, S. A. Lex, S. J. King, and S. P. Gross, “Cytoplasmic dynein functions as a gear in response to load,” Nature427(6975), 649–652 (2004).
[CrossRef] [PubMed]

Kong, X.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Korlach, J.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Krichevsky, O.

O. Krichevsky and G. Bonnet, “Fluorescence correlation spectroscopy: the technique and its applications,” Rep. Prog. Phys.65(2), 251–297 (2002).
[CrossRef]

Kuo, Y.

Y. Kuo, T.-Y. Hsu, Y.-C. Wu, and H.-C. Chang, “Fluorescent nanodiamond as a probe for the intercellular transport of proteins in vivo,” Biomaterials34(33), 8352–8360 (2013).
[CrossRef] [PubMed]

Kural, C.

C. Kural, H. Kim, S. Syed, G. Goshima, V. I. Gelfand, and P. R. Selvin, “Kinesin and Dynein Move a Peroxisome in Vivo: A Tug-of-War or Coordinated Movement?” Science308(5727), 1469–1472 (2005).
[CrossRef] [PubMed]

Kuse, R.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Lacroix, Y.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Lecuit, T.

T. Lecuit, “Junctions and vesicular trafficking during Drosophila cellularization,” J. Cell Sci.117(16), 3427–3433 (2004).
[CrossRef] [PubMed]

Lee, H. Y.

Y. R. Chang, H. Y. Lee, K. Chen, C. C. Chang, D. S. Tsai, C. C. Fu, T. S. Lim, Y. K. Tzeng, C. Y. Fang, C. C. Han, H. C. Chang, and W. Fann, “Mass production and dynamic imaging of fluorescent nanodiamonds,” Nat. Nanotechnol.3(5), 284–288 (2008).
[CrossRef] [PubMed]

C. C. Fu, H. Y. Lee, K. Chen, T. S. Lim, H. Y. Wu, P. K. Lin, P. K. Wei, P. H. Tsao, H. C. Chang, and W. Fann, “Characterization and application of single fluorescent nanodiamonds as cellular biomarkers,” Proc. Natl. Acad. Sci. U.S.A.104(3), 727–732 (2007).
[CrossRef] [PubMed]

Leung, T.

J. M. Crawford, N. Harden, T. Leung, L. Lim, and D. P. Kiehart, “Cellularization in Drosophila melanogaster Is Disrupted by the Inhibition of Rho Activity and the Activation of Cdc42 Function,” Dev. Biol.204(1), 151–164 (1998).
[CrossRef] [PubMed]

Lex, S. A.

R. Mallik, B. C. Carter, S. A. Lex, S. J. King, and S. P. Gross, “Cytoplasmic dynein functions as a gear in response to load,” Nature427(6975), 649–652 (2004).
[CrossRef] [PubMed]

Li, J. J.

X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, and S. Weiss, “Quantum dots for live cells, in vivo imaging, and diagnostics,” Science307(5709), 538–544 (2005).
[CrossRef] [PubMed]

Lim, L.

J. M. Crawford, N. Harden, T. Leung, L. Lim, and D. P. Kiehart, “Cellularization in Drosophila melanogaster Is Disrupted by the Inhibition of Rho Activity and the Activation of Cdc42 Function,” Dev. Biol.204(1), 151–164 (1998).
[CrossRef] [PubMed]

Lim, T. S.

Y. R. Chang, H. Y. Lee, K. Chen, C. C. Chang, D. S. Tsai, C. C. Fu, T. S. Lim, Y. K. Tzeng, C. Y. Fang, C. C. Han, H. C. Chang, and W. Fann, “Mass production and dynamic imaging of fluorescent nanodiamonds,” Nat. Nanotechnol.3(5), 284–288 (2008).
[CrossRef] [PubMed]

C. C. Fu, H. Y. Lee, K. Chen, T. S. Lim, H. Y. Wu, P. K. Lin, P. K. Wei, P. H. Tsao, H. C. Chang, and W. Fann, “Characterization and application of single fluorescent nanodiamonds as cellular biomarkers,” Proc. Natl. Acad. Sci. U.S.A.104(3), 727–732 (2007).
[CrossRef] [PubMed]

Lin, P. K.

C. C. Fu, H. Y. Lee, K. Chen, T. S. Lim, H. Y. Wu, P. K. Lin, P. K. Wei, P. H. Tsao, H. C. Chang, and W. Fann, “Characterization and application of single fluorescent nanodiamonds as cellular biomarkers,” Proc. Natl. Acad. Sci. U.S.A.104(3), 727–732 (2007).
[CrossRef] [PubMed]

Lin, S.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Liu, K.-K.

V. Vaijayanthimala, P.-Y. Cheng, S.-H. Yeh, K.-K. Liu, C.-H. Hsiao, J.-I. Chao, and H.-C. Chang, “The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent,” Biomaterials33(31), 7794–7802 (2012).
[CrossRef] [PubMed]

Lundquist, P.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Luong, K.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Lyle, J.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Ma, C.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Maclaurin, D.

L. P. McGuinness, Y. Yan, A. Stacey, D. A. Simpson, L. T. Hall, D. Maclaurin, S. Prawer, P. Mulvaney, J. Wrachtrup, F. Caruso, R. E. Scholten, and L. C. L. Hollenberg, “Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells,” Nat. Nanotechnol.6(6), 358–363 (2011).
[CrossRef] [PubMed]

Mallik, R.

R. Mallik, B. C. Carter, S. A. Lex, S. J. King, and S. P. Gross, “Cytoplasmic dynein functions as a gear in response to load,” Nature427(6975), 649–652 (2004).
[CrossRef] [PubMed]

Marks, P.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Maxham, M.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Mazumdar, A.

A. Mazumdar and M. Mazumdar, “How one becomes many: blastoderm cellularization in Drosophila melanogaster,” Bioessays24(11), 1012–1022 (2002).
[CrossRef] [PubMed]

Mazumdar, M.

A. Mazumdar and M. Mazumdar, “How one becomes many: blastoderm cellularization in Drosophila melanogaster,” Bioessays24(11), 1012–1022 (2002).
[CrossRef] [PubMed]

McGuinness, L. P.

L. P. McGuinness, Y. Yan, A. Stacey, D. A. Simpson, L. T. Hall, D. Maclaurin, S. Prawer, P. Mulvaney, J. Wrachtrup, F. Caruso, R. E. Scholten, and L. C. L. Hollenberg, “Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells,” Nat. Nanotechnol.6(6), 358–363 (2011).
[CrossRef] [PubMed]

Michalet, X.

X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, and S. Weiss, “Quantum dots for live cells, in vivo imaging, and diagnostics,” Science307(5709), 538–544 (2005).
[CrossRef] [PubMed]

Mohan, N.

N. Mohan, C.-S. Chen, H.-H. Hsieh, Y.-C. Wu, and H.-C. Chang, “In Vivo Imaging and Toxicity Assessments of Fluorescent Nanodiamonds in Caenorhabditis elegans,” Nano Lett.10(9), 3692–3699 (2010).
[CrossRef] [PubMed]

Mori, I.

R. Igarashi, Y. Yoshinari, H. Yokota, T. Sugi, F. Sugihara, K. Ikeda, H. Sumiya, S. Tsuji, I. Mori, H. Tochio, Y. Harada, and M. Shirakawa, “Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo,” Nano Lett.12(11), 5726–5732 (2012).
[CrossRef] [PubMed]

Mulvaney, P.

L. P. McGuinness, Y. Yan, A. Stacey, D. A. Simpson, L. T. Hall, D. Maclaurin, S. Prawer, P. Mulvaney, J. Wrachtrup, F. Caruso, R. E. Scholten, and L. C. L. Hollenberg, “Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells,” Nat. Nanotechnol.6(6), 358–363 (2011).
[CrossRef] [PubMed]

Murphy, D.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Otto, G.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Park, I.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Peluso, P.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Pham, T.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Phillips, M.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Pinaud, F. F.

X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, and S. Weiss, “Quantum dots for live cells, in vivo imaging, and diagnostics,” Science307(5709), 538–544 (2005).
[CrossRef] [PubMed]

Prawer, S.

L. P. McGuinness, Y. Yan, A. Stacey, D. A. Simpson, L. T. Hall, D. Maclaurin, S. Prawer, P. Mulvaney, J. Wrachtrup, F. Caruso, R. E. Scholten, and L. C. L. Hollenberg, “Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells,” Nat. Nanotechnol.6(6), 358–363 (2011).
[CrossRef] [PubMed]

Rank, D.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Roy, J.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Royou, A.

A. Royou, C. Field, J. C. Sisson, W. Sullivan, and R. Karess, “Reassessing the role and dynamics of nonmuscle myosin II during furrow formation in early Drosophila embryos,” Mol. Biol. Cell15(2), 838–850 (2003).
[CrossRef] [PubMed]

Sauvage, T.

O. Faklaris, D. Garrot, V. Joshi, F. Druon, J. P. Boudou, T. Sauvage, P. Georges, P. A. Curmi, and F. Treussart, “Detection of single photoluminescent diamond nanoparticles in cells and study of the internalization pathway,” Small4(12), 2236–2239 (2008).
[CrossRef] [PubMed]

Saxton, M. J.

M. J. Saxton and K. Jacobson, “Single-particle tracking: Applications to Membrane Dynamics,” Annu. Rev. Biophys. Biomol. Struct.26(1), 373–399 (1997).
[CrossRef] [PubMed]

Schnitzer, M. J.

K. Visscher, M. J. Schnitzer, and S. M. Block, “Single kinesin molecules studied with a molecular force clamp,” Nature400(6740), 184–189 (1999).
[CrossRef] [PubMed]

Scholten, R. E.

L. P. McGuinness, Y. Yan, A. Stacey, D. A. Simpson, L. T. Hall, D. Maclaurin, S. Prawer, P. Mulvaney, J. Wrachtrup, F. Caruso, R. E. Scholten, and L. C. L. Hollenberg, “Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells,” Nat. Nanotechnol.6(6), 358–363 (2011).
[CrossRef] [PubMed]

Sebra, R.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Selvin, P. R.

C. Kural, H. Kim, S. Syed, G. Goshima, V. I. Gelfand, and P. R. Selvin, “Kinesin and Dynein Move a Peroxisome in Vivo: A Tug-of-War or Coordinated Movement?” Science308(5727), 1469–1472 (2005).
[CrossRef] [PubMed]

Sennour, M.

O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J. C. Arnault, A. Thorel, J. P. Boudou, P. A. Curmi, and F. Treussart, “Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells,” ACS Nano3(12), 3955–3962 (2009).
[CrossRef] [PubMed]

Sheetz, M. P.

M. P. Sheetz and J. A. Spudich, “Movement of myosin-coated fluorescent beads on actin cables in vitro,” Nature303(5912), 31–35 (1983).
[CrossRef] [PubMed]

M. P. Sheetz and J. A. Spudich, “Movement of myosin-coated fluorescent beads on actin cables in vitro,” Nature303, 31–35 (1983).

Shen, G.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Shirakawa, M.

R. Igarashi, Y. Yoshinari, H. Yokota, T. Sugi, F. Sugihara, K. Ikeda, H. Sumiya, S. Tsuji, I. Mori, H. Tochio, Y. Harada, and M. Shirakawa, “Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo,” Nano Lett.12(11), 5726–5732 (2012).
[CrossRef] [PubMed]

Simpson, D. A.

L. P. McGuinness, Y. Yan, A. Stacey, D. A. Simpson, L. T. Hall, D. Maclaurin, S. Prawer, P. Mulvaney, J. Wrachtrup, F. Caruso, R. E. Scholten, and L. C. L. Hollenberg, “Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells,” Nat. Nanotechnol.6(6), 358–363 (2011).
[CrossRef] [PubMed]

Sisson, J. C.

A. Royou, C. Field, J. C. Sisson, W. Sullivan, and R. Karess, “Reassessing the role and dynamics of nonmuscle myosin II during furrow formation in early Drosophila embryos,” Mol. Biol. Cell15(2), 838–850 (2003).
[CrossRef] [PubMed]

Sokac, A. M.

A. M. Sokac and E. Wieschaus, “Local actin-dependent endocytosis is zygotically controlled to initiate Drosophila cellularization,” Dev. Cell14(5), 775–786 (2008).
[CrossRef] [PubMed]

Sorenson, J.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Spudich, J. A.

M. P. Sheetz and J. A. Spudich, “Movement of myosin-coated fluorescent beads on actin cables in vitro,” Nature303(5912), 31–35 (1983).
[CrossRef] [PubMed]

M. P. Sheetz and J. A. Spudich, “Movement of myosin-coated fluorescent beads on actin cables in vitro,” Nature303, 31–35 (1983).

Stacey, A.

L. P. McGuinness, Y. Yan, A. Stacey, D. A. Simpson, L. T. Hall, D. Maclaurin, S. Prawer, P. Mulvaney, J. Wrachtrup, F. Caruso, R. E. Scholten, and L. C. L. Hollenberg, “Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells,” Nat. Nanotechnol.6(6), 358–363 (2011).
[CrossRef] [PubMed]

Sugi, T.

R. Igarashi, Y. Yoshinari, H. Yokota, T. Sugi, F. Sugihara, K. Ikeda, H. Sumiya, S. Tsuji, I. Mori, H. Tochio, Y. Harada, and M. Shirakawa, “Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo,” Nano Lett.12(11), 5726–5732 (2012).
[CrossRef] [PubMed]

Sugihara, F.

R. Igarashi, Y. Yoshinari, H. Yokota, T. Sugi, F. Sugihara, K. Ikeda, H. Sumiya, S. Tsuji, I. Mori, H. Tochio, Y. Harada, and M. Shirakawa, “Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo,” Nano Lett.12(11), 5726–5732 (2012).
[CrossRef] [PubMed]

Sullivan, W.

A. Royou, C. Field, J. C. Sisson, W. Sullivan, and R. Karess, “Reassessing the role and dynamics of nonmuscle myosin II during furrow formation in early Drosophila embryos,” Mol. Biol. Cell15(2), 838–850 (2003).
[CrossRef] [PubMed]

Sumiya, H.

R. Igarashi, Y. Yoshinari, H. Yokota, T. Sugi, F. Sugihara, K. Ikeda, H. Sumiya, S. Tsuji, I. Mori, H. Tochio, Y. Harada, and M. Shirakawa, “Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo,” Nano Lett.12(11), 5726–5732 (2012).
[CrossRef] [PubMed]

Sundaresan, G.

X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, and S. Weiss, “Quantum dots for live cells, in vivo imaging, and diagnostics,” Science307(5709), 538–544 (2005).
[CrossRef] [PubMed]

Syed, S.

C. Kural, H. Kim, S. Syed, G. Goshima, V. I. Gelfand, and P. R. Selvin, “Kinesin and Dynein Move a Peroxisome in Vivo: A Tug-of-War or Coordinated Movement?” Science308(5727), 1469–1472 (2005).
[CrossRef] [PubMed]

Tauc, P.

O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J. C. Arnault, A. Thorel, J. P. Boudou, P. A. Curmi, and F. Treussart, “Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells,” ACS Nano3(12), 3955–3962 (2009).
[CrossRef] [PubMed]

Thorel, A.

O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J. C. Arnault, A. Thorel, J. P. Boudou, P. A. Curmi, and F. Treussart, “Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells,” ACS Nano3(12), 3955–3962 (2009).
[CrossRef] [PubMed]

Tochio, H.

R. Igarashi, Y. Yoshinari, H. Yokota, T. Sugi, F. Sugihara, K. Ikeda, H. Sumiya, S. Tsuji, I. Mori, H. Tochio, Y. Harada, and M. Shirakawa, “Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo,” Nano Lett.12(11), 5726–5732 (2012).
[CrossRef] [PubMed]

Tomaney, A.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Travers, K.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Treussart, F.

O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J. C. Arnault, A. Thorel, J. P. Boudou, P. A. Curmi, and F. Treussart, “Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells,” ACS Nano3(12), 3955–3962 (2009).
[CrossRef] [PubMed]

O. Faklaris, D. Garrot, V. Joshi, F. Druon, J. P. Boudou, T. Sauvage, P. Georges, P. A. Curmi, and F. Treussart, “Detection of single photoluminescent diamond nanoparticles in cells and study of the internalization pathway,” Small4(12), 2236–2239 (2008).
[CrossRef] [PubMed]

Trulson, M.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Trusheim, M. E.

E. H. Chen, O. Gaathon, M. E. Trusheim, and D. Englund, “Wide-Field Multispectral Super-Resolution Imaging Using Spin-Dependent Fluorescence in Nanodiamonds,” Nano Lett.13(5), 2073–2077 (2013).
[CrossRef] [PubMed]

Tsai, D. S.

Y. R. Chang, H. Y. Lee, K. Chen, C. C. Chang, D. S. Tsai, C. C. Fu, T. S. Lim, Y. K. Tzeng, C. Y. Fang, C. C. Han, H. C. Chang, and W. Fann, “Mass production and dynamic imaging of fluorescent nanodiamonds,” Nat. Nanotechnol.3(5), 284–288 (2008).
[CrossRef] [PubMed]

Tsao, P. H.

C. C. Fu, H. Y. Lee, K. Chen, T. S. Lim, H. Y. Wu, P. K. Lin, P. K. Wei, P. H. Tsao, H. C. Chang, and W. Fann, “Characterization and application of single fluorescent nanodiamonds as cellular biomarkers,” Proc. Natl. Acad. Sci. U.S.A.104(3), 727–732 (2007).
[CrossRef] [PubMed]

Tsay, J. M.

X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, and S. Weiss, “Quantum dots for live cells, in vivo imaging, and diagnostics,” Science307(5709), 538–544 (2005).
[CrossRef] [PubMed]

Tsuji, S.

R. Igarashi, Y. Yoshinari, H. Yokota, T. Sugi, F. Sugihara, K. Ikeda, H. Sumiya, S. Tsuji, I. Mori, H. Tochio, Y. Harada, and M. Shirakawa, “Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo,” Nano Lett.12(11), 5726–5732 (2012).
[CrossRef] [PubMed]

Turner, S.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Tzeng, Y. K.

Y. R. Chang, H. Y. Lee, K. Chen, C. C. Chang, D. S. Tsai, C. C. Fu, T. S. Lim, Y. K. Tzeng, C. Y. Fang, C. C. Han, H. C. Chang, and W. Fann, “Mass production and dynamic imaging of fluorescent nanodiamonds,” Nat. Nanotechnol.3(5), 284–288 (2008).
[CrossRef] [PubMed]

Vaijayanthimala, V.

V. Vaijayanthimala, P.-Y. Cheng, S.-H. Yeh, K.-K. Liu, C.-H. Hsiao, J.-I. Chao, and H.-C. Chang, “The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent,” Biomaterials33(31), 7794–7802 (2012).
[CrossRef] [PubMed]

Vieceli, J.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Visscher, K.

K. Visscher, M. J. Schnitzer, and S. M. Block, “Single kinesin molecules studied with a molecular force clamp,” Nature400(6740), 184–189 (1999).
[CrossRef] [PubMed]

Wegener, J.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Wei, P. K.

C. C. Fu, H. Y. Lee, K. Chen, T. S. Lim, H. Y. Wu, P. K. Lin, P. K. Wei, P. H. Tsao, H. C. Chang, and W. Fann, “Characterization and application of single fluorescent nanodiamonds as cellular biomarkers,” Proc. Natl. Acad. Sci. U.S.A.104(3), 727–732 (2007).
[CrossRef] [PubMed]

Weiss, S.

X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, and S. Weiss, “Quantum dots for live cells, in vivo imaging, and diagnostics,” Science307(5709), 538–544 (2005).
[CrossRef] [PubMed]

Wieschaus, E.

A. M. Sokac and E. Wieschaus, “Local actin-dependent endocytosis is zygotically controlled to initiate Drosophila cellularization,” Dev. Cell14(5), 775–786 (2008).
[CrossRef] [PubMed]

Wrachtrup, J.

L. P. McGuinness, Y. Yan, A. Stacey, D. A. Simpson, L. T. Hall, D. Maclaurin, S. Prawer, P. Mulvaney, J. Wrachtrup, F. Caruso, R. E. Scholten, and L. C. L. Hollenberg, “Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells,” Nat. Nanotechnol.6(6), 358–363 (2011).
[CrossRef] [PubMed]

Wu, A. M.

X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, and S. Weiss, “Quantum dots for live cells, in vivo imaging, and diagnostics,” Science307(5709), 538–544 (2005).
[CrossRef] [PubMed]

Wu, D.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Wu, H. Y.

C. C. Fu, H. Y. Lee, K. Chen, T. S. Lim, H. Y. Wu, P. K. Lin, P. K. Wei, P. H. Tsao, H. C. Chang, and W. Fann, “Characterization and application of single fluorescent nanodiamonds as cellular biomarkers,” Proc. Natl. Acad. Sci. U.S.A.104(3), 727–732 (2007).
[CrossRef] [PubMed]

Wu, Y.-C.

Y. Kuo, T.-Y. Hsu, Y.-C. Wu, and H.-C. Chang, “Fluorescent nanodiamond as a probe for the intercellular transport of proteins in vivo,” Biomaterials34(33), 8352–8360 (2013).
[CrossRef] [PubMed]

N. Mohan, C.-S. Chen, H.-H. Hsieh, Y.-C. Wu, and H.-C. Chang, “In Vivo Imaging and Toxicity Assessments of Fluorescent Nanodiamonds in Caenorhabditis elegans,” Nano Lett.10(9), 3692–3699 (2010).
[CrossRef] [PubMed]

Yan, Y.

L. P. McGuinness, Y. Yan, A. Stacey, D. A. Simpson, L. T. Hall, D. Maclaurin, S. Prawer, P. Mulvaney, J. Wrachtrup, F. Caruso, R. E. Scholten, and L. C. L. Hollenberg, “Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells,” Nat. Nanotechnol.6(6), 358–363 (2011).
[CrossRef] [PubMed]

Yang, A.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Yeh, S.-H.

V. Vaijayanthimala, P.-Y. Cheng, S.-H. Yeh, K.-K. Liu, C.-H. Hsiao, J.-I. Chao, and H.-C. Chang, “The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent,” Biomaterials33(31), 7794–7802 (2012).
[CrossRef] [PubMed]

Yokota, H.

R. Igarashi, Y. Yoshinari, H. Yokota, T. Sugi, F. Sugihara, K. Ikeda, H. Sumiya, S. Tsuji, I. Mori, H. Tochio, Y. Harada, and M. Shirakawa, “Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo,” Nano Lett.12(11), 5726–5732 (2012).
[CrossRef] [PubMed]

Yoshinari, Y.

R. Igarashi, Y. Yoshinari, H. Yokota, T. Sugi, F. Sugihara, K. Ikeda, H. Sumiya, S. Tsuji, I. Mori, H. Tochio, Y. Harada, and M. Shirakawa, “Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo,” Nano Lett.12(11), 5726–5732 (2012).
[CrossRef] [PubMed]

Zaccarin, D.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Zhao, P.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

Zhong, F.

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

ACS Nano (1)

O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J. C. Arnault, A. Thorel, J. P. Boudou, P. A. Curmi, and F. Treussart, “Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells,” ACS Nano3(12), 3955–3962 (2009).
[CrossRef] [PubMed]

Annu. Rev. Biophys. Biomol. Struct. (1)

M. J. Saxton and K. Jacobson, “Single-particle tracking: Applications to Membrane Dynamics,” Annu. Rev. Biophys. Biomol. Struct.26(1), 373–399 (1997).
[CrossRef] [PubMed]

Bioessays (1)

A. Mazumdar and M. Mazumdar, “How one becomes many: blastoderm cellularization in Drosophila melanogaster,” Bioessays24(11), 1012–1022 (2002).
[CrossRef] [PubMed]

Biomaterials (2)

V. Vaijayanthimala, P.-Y. Cheng, S.-H. Yeh, K.-K. Liu, C.-H. Hsiao, J.-I. Chao, and H.-C. Chang, “The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent,” Biomaterials33(31), 7794–7802 (2012).
[CrossRef] [PubMed]

Y. Kuo, T.-Y. Hsu, Y.-C. Wu, and H.-C. Chang, “Fluorescent nanodiamond as a probe for the intercellular transport of proteins in vivo,” Biomaterials34(33), 8352–8360 (2013).
[CrossRef] [PubMed]

Dev. Biol. (1)

J. M. Crawford, N. Harden, T. Leung, L. Lim, and D. P. Kiehart, “Cellularization in Drosophila melanogaster Is Disrupted by the Inhibition of Rho Activity and the Activation of Cdc42 Function,” Dev. Biol.204(1), 151–164 (1998).
[CrossRef] [PubMed]

Dev. Cell (1)

A. M. Sokac and E. Wieschaus, “Local actin-dependent endocytosis is zygotically controlled to initiate Drosophila cellularization,” Dev. Cell14(5), 775–786 (2008).
[CrossRef] [PubMed]

J. Cell Sci. (1)

T. Lecuit, “Junctions and vesicular trafficking during Drosophila cellularization,” J. Cell Sci.117(16), 3427–3433 (2004).
[CrossRef] [PubMed]

Mol. Biol. Cell (1)

A. Royou, C. Field, J. C. Sisson, W. Sullivan, and R. Karess, “Reassessing the role and dynamics of nonmuscle myosin II during furrow formation in early Drosophila embryos,” Mol. Biol. Cell15(2), 838–850 (2003).
[CrossRef] [PubMed]

Nano Lett. (3)

R. Igarashi, Y. Yoshinari, H. Yokota, T. Sugi, F. Sugihara, K. Ikeda, H. Sumiya, S. Tsuji, I. Mori, H. Tochio, Y. Harada, and M. Shirakawa, “Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo,” Nano Lett.12(11), 5726–5732 (2012).
[CrossRef] [PubMed]

N. Mohan, C.-S. Chen, H.-H. Hsieh, Y.-C. Wu, and H.-C. Chang, “In Vivo Imaging and Toxicity Assessments of Fluorescent Nanodiamonds in Caenorhabditis elegans,” Nano Lett.10(9), 3692–3699 (2010).
[CrossRef] [PubMed]

E. H. Chen, O. Gaathon, M. E. Trusheim, and D. Englund, “Wide-Field Multispectral Super-Resolution Imaging Using Spin-Dependent Fluorescence in Nanodiamonds,” Nano Lett.13(5), 2073–2077 (2013).
[CrossRef] [PubMed]

Nat. Nanotechnol. (2)

Y. R. Chang, H. Y. Lee, K. Chen, C. C. Chang, D. S. Tsai, C. C. Fu, T. S. Lim, Y. K. Tzeng, C. Y. Fang, C. C. Han, H. C. Chang, and W. Fann, “Mass production and dynamic imaging of fluorescent nanodiamonds,” Nat. Nanotechnol.3(5), 284–288 (2008).
[CrossRef] [PubMed]

L. P. McGuinness, Y. Yan, A. Stacey, D. A. Simpson, L. T. Hall, D. Maclaurin, S. Prawer, P. Mulvaney, J. Wrachtrup, F. Caruso, R. E. Scholten, and L. C. L. Hollenberg, “Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells,” Nat. Nanotechnol.6(6), 358–363 (2011).
[CrossRef] [PubMed]

Nature (4)

K. Visscher, M. J. Schnitzer, and S. M. Block, “Single kinesin molecules studied with a molecular force clamp,” Nature400(6740), 184–189 (1999).
[CrossRef] [PubMed]

M. P. Sheetz and J. A. Spudich, “Movement of myosin-coated fluorescent beads on actin cables in vitro,” Nature303(5912), 31–35 (1983).
[CrossRef] [PubMed]

M. P. Sheetz and J. A. Spudich, “Movement of myosin-coated fluorescent beads on actin cables in vitro,” Nature303, 31–35 (1983).

R. Mallik, B. C. Carter, S. A. Lex, S. J. King, and S. P. Gross, “Cytoplasmic dynein functions as a gear in response to load,” Nature427(6975), 649–652 (2004).
[CrossRef] [PubMed]

Proc. Natl. Acad. Sci. U.S.A. (1)

C. C. Fu, H. Y. Lee, K. Chen, T. S. Lim, H. Y. Wu, P. K. Lin, P. K. Wei, P. H. Tsao, H. C. Chang, and W. Fann, “Characterization and application of single fluorescent nanodiamonds as cellular biomarkers,” Proc. Natl. Acad. Sci. U.S.A.104(3), 727–732 (2007).
[CrossRef] [PubMed]

Rep. Prog. Phys. (1)

O. Krichevsky and G. Bonnet, “Fluorescence correlation spectroscopy: the technique and its applications,” Rep. Prog. Phys.65(2), 251–297 (2002).
[CrossRef]

Science (3)

C. Kural, H. Kim, S. Syed, G. Goshima, V. I. Gelfand, and P. R. Selvin, “Kinesin and Dynein Move a Peroxisome in Vivo: A Tug-of-War or Coordinated Movement?” Science308(5727), 1469–1472 (2005).
[CrossRef] [PubMed]

J. Eid, A. Fehr, J. Gray, K. Luong, J. Lyle, G. Otto, P. Peluso, D. Rank, P. Baybayan, B. Bettman, A. Bibillo, K. Bjornson, B. Chaudhuri, F. Christians, R. Cicero, S. Clark, R. Dalal, A. Dewinter, J. Dixon, M. Foquet, A. Gaertner, P. Hardenbol, C. Heiner, K. Hester, D. Holden, G. Kearns, X. Kong, R. Kuse, Y. Lacroix, S. Lin, P. Lundquist, C. Ma, P. Marks, M. Maxham, D. Murphy, I. Park, T. Pham, M. Phillips, J. Roy, R. Sebra, G. Shen, J. Sorenson, A. Tomaney, K. Travers, M. Trulson, J. Vieceli, J. Wegener, D. Wu, A. Yang, D. Zaccarin, P. Zhao, F. Zhong, J. Korlach, and S. Turner, “Real-Time DNA Sequencing from Single Polymerase Molecules,” Science323(5910), 133–138 (2009).
[CrossRef] [PubMed]

X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, and S. Weiss, “Quantum dots for live cells, in vivo imaging, and diagnostics,” Science307(5709), 538–544 (2005).
[CrossRef] [PubMed]

Small (1)

O. Faklaris, D. Garrot, V. Joshi, F. Druon, J. P. Boudou, T. Sauvage, P. Georges, P. A. Curmi, and F. Treussart, “Detection of single photoluminescent diamond nanoparticles in cells and study of the internalization pathway,” Small4(12), 2236–2239 (2008).
[CrossRef] [PubMed]

Other (1)

R. M. Mazo, Brownian Motion: Fluctuations, Dynamics, and Applications (Clarendon press Oxford, 2002).

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (6)

Fig. 1
Fig. 1

a. Schematic of the micro-injection of nanodiamonds into the Drosophila embryo. b-c. Early (b) and late (c) stage 5 embryos showing the cellularization furrows introgressing between nuclei, which invade the yolk-free periplasm during the later syncytial divisions (b, arrows). The ingressing membranes eventually join and pinch off individual blastoderm cells, forming as a consequence a large, internal yolk cell. Nanodiamonds that have diffused into the yolk-free periplasm can become internalized in the blastoderm cells at the completion of stage 5 (c).

Fig. 2
Fig. 2

Scanning confocal fluorescence image of individual nanodiamonds in the blastoderm cells during stage 5 of development. The image shows the auto-fluorescence from the introgressing cellularization furrows defining each blastoderm cell as well as the strong fluorescent signal from individual nanodiamonds which in the majority of cases is localized to the cell periphery.

Fig. 3
Fig. 3

Typical FCS from a freely diffusing nanodiamond in a blastoderm cell (solid blue line). The solid green line is a fit to the data using Eq. (1) with the exacted parameter D = (8.27 ± 0.01) × 10−3 µm2/s.

Fig. 4
Fig. 4

FCS from a nanodiamond undergoing driven motion (solid blue line). The solid green line is a fit to the data using Eq. (2). The extracted diffusion coefficient and velocity from the fit was D = (1.41 ± 0.01) × 10−3 µm2/s and v = 0.030 ± 0.003 μm/s.

Fig. 5
Fig. 5

Wide-field fluorescence image from nanodiamonds micro-injected into a Drosophila melanogaster embryo. The red lines represent the trajectories of the nanodiamonds over a 5 second period.

Fig. 6
Fig. 6

Particle trajectories from four individual nanodiamonds (I-IV) in the furrow periplasm during stage 5 of development. The mean squared displacement as a function of time is shown below for each respective trajectory (I-IV).

Equations (4)

Equations on this page are rendered with MathJax. Learn more.

G(τ)= 1 N ¯ (1+ τ τd ) 1 (1+ τ ω 2 τd ) 1/2 ,
G ( τ ) = 1 N ¯ ( 1 + τ τ d ) 1 ( 1 + τ ω 2 τ d ) 1 / 2 exp [ ( τ τ d ) 2 1 1 + τ τ d ] ,
f e =v k b T/D,
| x | 2 = k=1 N | x | 2 =(2n)Dt+ ( v x t) 2 ,

Metrics