Abstract

An optical fiber sensor for monitoring low dose radiation is presented. The sensor, based on radiation sensitive scintillation material, terbium doped gadolinium oxysulphide (Gd2O2S:Tb), is embedded in a cavity of 700µm diameter within a 1mm plastic optical fiber. The sensor is compared with the treatment planning system for repeatability, angular dependency, distance and accumulated radiation activity. The sensor demonstrates a high sensitivity of 152 photon counts/Gy with a temporal resolution of 0.1 seconds, with the largest repeatability error of 4.1%, to 0.361mCi of Iodine-125 the radioactive source most commonly used in LDR brachytherapy for treating prostate cancer.

© 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

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    [Crossref]

2017 (1)

P. Woulfe, S. O’Keeffe, and F. J. Sullivan, “EP-1800: Optical Fiber Luminescence Sensor for Real-time LDR Brachytherapy Dosimetry,” Radiother. Oncol. 123, S988–S989 (2017).
[Crossref]

2015 (1)

S. O’Keeffe, D. McCarthy, P. Woulfe, M. W. Grattan, A. R. Hounsell, D. Sporea, L. Mihai, I. Vata, G. Leen, and E. Lewis, “A review of recent advances in optical fiber sensors for in vivo dosimetry during radiotherapy,” Br. J. Radiol. 88(1050), 20140702 (2015).
[Crossref]

2014 (1)

G. Kertzscher, A. Rosenfeld, S. Beddar, K. Tanderup, and J. E. Cygler, “In vivo dosimetry: trends and prospects for brachytherapy,” Br. J. Radiol. 87(1041), 20140206 (2014).
[Crossref]

2013 (1)

K. Tanderup, S. Beddar, C. E. Andersen, G. Kertzscher, and J. E. Cygler, “In vivo dosimetry in brachytherapy,” Med. Phys. 40(7), 070902 (2013).
[Crossref]

2012 (2)

L. Beaulieu, Å. Carlsson Tedgren, J.-F. Carrier, S. D. Davis, F. Mourtada, M. J. Rivard, R. M. Thomson, F. Verhaegen, T. A. Wareing, and J. F. Williamson, “Report of the Task Group 186 on model-based dose calculation methods in brachytherapy beyond the TG-43 formalism: Current status and recommendations for clinical implementation,” Med. Phys. 39(10), 6208–6236 (2012).
[Crossref]

F. Mourtada, J. Mikell, and G. Ibbott, “Monte Carlo calculations of AAPM Task Group Report No. 43 dosimetry parameters for the (125)I I-Seed AgX100 source model,” Brachytherapy 11(3), 237–244 (2012).
[Crossref]

2011 (2)

S. Strohmaier and G. Zwierzchowski, “Comparison of (60)Co and (192)Ir sources in HDR brachytherapy,” J. Contemp. Brachytherapy 4, 199–208 (2011).
[Crossref]

G. Kertzscher, C. E. Andersen, F. A. Siebert, S. K. Nielsen, J. C. Lindegaard, and K. Tanderup, “Identifying afterloading PDR and HDR brachytherapy errors using real-time fiber-coupled Al(2)O(3):C dosimetry and a novel statistical error decision criterion,” Radiother. Oncol. 100(3), 456–462 (2011).
[Crossref]

2010 (2)

J. Cunningham, M. Coffey, T. Knoos, and O. Holmberg, “Radiation Oncology Safety Information System (ROSIS)–profiles of participants and the first 1074 incident reports,” Radiother. Oncol. 97(3), 601–607 (2010).
[Crossref]

O. Holmberg, J. Malone, M. Rehani, D. McLean, and R. Czarwinski, “Current issues and actions in radiation protection of patients,” Eur. J. Radiol. 76(1), 15–19 (2010).
[Crossref]

2007 (1)

C. Kirisits, F.-A. Siebert, D. Baltas, M. De Brabandere, T. P. Hellebust, D. Berger, and J. Venselaar, “Accuracy of volume and DVH parameters determined with different brachytherapy treatment planning systems,” Radiother. Oncol. 84(3), 290–297 (2007).
[Crossref]

2005 (1)

J. Valentin, “Preface, Main Points, Introduction, Chapters 2 and 3,” Ann. ICRP 35(2), 1–9 (2005).
[Crossref]

2004 (3)

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. S. Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. Saiful Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

S. G. Moreira, J. D. Seigne, R. C. Ordorica, J. M. Pow-Sang, and J. L. Lockhart, “2004: Devastating Complications following Brachytherapy in the Treatment of Prostate Adenocarcinoma,” J. Urol. 171(4S), 283 (2004).
[Crossref]

2001 (1)

V. Chambrette, S. Hardy, and J. C. Nenot, “Radiological accidents Database establishment “ACCIRAD” at IPSN,” Radioprotection 36(4), 477–510 (2001).
[Crossref]

Andersen, C. E.

K. Tanderup, S. Beddar, C. E. Andersen, G. Kertzscher, and J. E. Cygler, “In vivo dosimetry in brachytherapy,” Med. Phys. 40(7), 070902 (2013).
[Crossref]

G. Kertzscher, C. E. Andersen, F. A. Siebert, S. K. Nielsen, J. C. Lindegaard, and K. Tanderup, “Identifying afterloading PDR and HDR brachytherapy errors using real-time fiber-coupled Al(2)O(3):C dosimetry and a novel statistical error decision criterion,” Radiother. Oncol. 100(3), 456–462 (2011).
[Crossref]

Baltas, D.

C. Kirisits, F.-A. Siebert, D. Baltas, M. De Brabandere, T. P. Hellebust, D. Berger, and J. Venselaar, “Accuracy of volume and DVH parameters determined with different brachytherapy treatment planning systems,” Radiother. Oncol. 84(3), 290–297 (2007).
[Crossref]

Beaulieu, L.

L. Beaulieu, Å. Carlsson Tedgren, J.-F. Carrier, S. D. Davis, F. Mourtada, M. J. Rivard, R. M. Thomson, F. Verhaegen, T. A. Wareing, and J. F. Williamson, “Report of the Task Group 186 on model-based dose calculation methods in brachytherapy beyond the TG-43 formalism: Current status and recommendations for clinical implementation,” Med. Phys. 39(10), 6208–6236 (2012).
[Crossref]

Beddar, S.

G. Kertzscher, A. Rosenfeld, S. Beddar, K. Tanderup, and J. E. Cygler, “In vivo dosimetry: trends and prospects for brachytherapy,” Br. J. Radiol. 87(1041), 20140206 (2014).
[Crossref]

K. Tanderup, S. Beddar, C. E. Andersen, G. Kertzscher, and J. E. Cygler, “In vivo dosimetry in brachytherapy,” Med. Phys. 40(7), 070902 (2013).
[Crossref]

Berger, D.

C. Kirisits, F.-A. Siebert, D. Baltas, M. De Brabandere, T. P. Hellebust, D. Berger, and J. Venselaar, “Accuracy of volume and DVH parameters determined with different brachytherapy treatment planning systems,” Radiother. Oncol. 84(3), 290–297 (2007).
[Crossref]

Carlsson Tedgren, Å.

L. Beaulieu, Å. Carlsson Tedgren, J.-F. Carrier, S. D. Davis, F. Mourtada, M. J. Rivard, R. M. Thomson, F. Verhaegen, T. A. Wareing, and J. F. Williamson, “Report of the Task Group 186 on model-based dose calculation methods in brachytherapy beyond the TG-43 formalism: Current status and recommendations for clinical implementation,” Med. Phys. 39(10), 6208–6236 (2012).
[Crossref]

Carrier, J.-F.

L. Beaulieu, Å. Carlsson Tedgren, J.-F. Carrier, S. D. Davis, F. Mourtada, M. J. Rivard, R. M. Thomson, F. Verhaegen, T. A. Wareing, and J. F. Williamson, “Report of the Task Group 186 on model-based dose calculation methods in brachytherapy beyond the TG-43 formalism: Current status and recommendations for clinical implementation,” Med. Phys. 39(10), 6208–6236 (2012).
[Crossref]

Chambrette, V.

V. Chambrette, S. Hardy, and J. C. Nenot, “Radiological accidents Database establishment “ACCIRAD” at IPSN,” Radioprotection 36(4), 477–510 (2001).
[Crossref]

Coffey, M.

J. Cunningham, M. Coffey, T. Knoos, and O. Holmberg, “Radiation Oncology Safety Information System (ROSIS)–profiles of participants and the first 1074 incident reports,” Radiother. Oncol. 97(3), 601–607 (2010).
[Crossref]

Coursey, B. M.

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. Saiful Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. S. Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

Cronin, J.

P. Woulfe, S. O. Keeffe, D. McCarthy, M. Grattan, A. Hounsell, J. Cronin, and E. Lewis, “Characterisation of radioluminesence based optical fiber dosimeter in radiotherapy beam applications,” in SENSORS, 2013 IEEE, (2013), 1–4.

Cunningham, J.

J. Cunningham, M. Coffey, T. Knoos, and O. Holmberg, “Radiation Oncology Safety Information System (ROSIS)–profiles of participants and the first 1074 incident reports,” Radiother. Oncol. 97(3), 601–607 (2010).
[Crossref]

Cygler, J. E.

G. Kertzscher, A. Rosenfeld, S. Beddar, K. Tanderup, and J. E. Cygler, “In vivo dosimetry: trends and prospects for brachytherapy,” Br. J. Radiol. 87(1041), 20140206 (2014).
[Crossref]

K. Tanderup, S. Beddar, C. E. Andersen, G. Kertzscher, and J. E. Cygler, “In vivo dosimetry in brachytherapy,” Med. Phys. 40(7), 070902 (2013).
[Crossref]

Czarwinski, R.

O. Holmberg, J. Malone, M. Rehani, D. McLean, and R. Czarwinski, “Current issues and actions in radiation protection of patients,” Eur. J. Radiol. 76(1), 15–19 (2010).
[Crossref]

Davis, S. D.

L. Beaulieu, Å. Carlsson Tedgren, J.-F. Carrier, S. D. Davis, F. Mourtada, M. J. Rivard, R. M. Thomson, F. Verhaegen, T. A. Wareing, and J. F. Williamson, “Report of the Task Group 186 on model-based dose calculation methods in brachytherapy beyond the TG-43 formalism: Current status and recommendations for clinical implementation,” Med. Phys. 39(10), 6208–6236 (2012).
[Crossref]

De Brabandere, M.

C. Kirisits, F.-A. Siebert, D. Baltas, M. De Brabandere, T. P. Hellebust, D. Berger, and J. Venselaar, “Accuracy of volume and DVH parameters determined with different brachytherapy treatment planning systems,” Radiother. Oncol. 84(3), 290–297 (2007).
[Crossref]

DeWerd, L. A.

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. S. Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. Saiful Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

Grattan, M.

P. Woulfe, S. O. Keeffe, D. McCarthy, M. Grattan, A. Hounsell, J. Cronin, and E. Lewis, “Characterisation of radioluminesence based optical fiber dosimeter in radiotherapy beam applications,” in SENSORS, 2013 IEEE, (2013), 1–4.

Grattan, M. W.

S. O’Keeffe, D. McCarthy, P. Woulfe, M. W. Grattan, A. R. Hounsell, D. Sporea, L. Mihai, I. Vata, G. Leen, and E. Lewis, “A review of recent advances in optical fiber sensors for in vivo dosimetry during radiotherapy,” Br. J. Radiol. 88(1050), 20140702 (2015).
[Crossref]

Hanson, W. F.

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. Saiful Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. S. Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

Hardy, S.

V. Chambrette, S. Hardy, and J. C. Nenot, “Radiological accidents Database establishment “ACCIRAD” at IPSN,” Radioprotection 36(4), 477–510 (2001).
[Crossref]

Hellebust, T. P.

C. Kirisits, F.-A. Siebert, D. Baltas, M. De Brabandere, T. P. Hellebust, D. Berger, and J. Venselaar, “Accuracy of volume and DVH parameters determined with different brachytherapy treatment planning systems,” Radiother. Oncol. 84(3), 290–297 (2007).
[Crossref]

Holmberg, O.

O. Holmberg, J. Malone, M. Rehani, D. McLean, and R. Czarwinski, “Current issues and actions in radiation protection of patients,” Eur. J. Radiol. 76(1), 15–19 (2010).
[Crossref]

J. Cunningham, M. Coffey, T. Knoos, and O. Holmberg, “Radiation Oncology Safety Information System (ROSIS)–profiles of participants and the first 1074 incident reports,” Radiother. Oncol. 97(3), 601–607 (2010).
[Crossref]

Hounsell, A.

P. Woulfe, S. O. Keeffe, D. McCarthy, M. Grattan, A. Hounsell, J. Cronin, and E. Lewis, “Characterisation of radioluminesence based optical fiber dosimeter in radiotherapy beam applications,” in SENSORS, 2013 IEEE, (2013), 1–4.

Hounsell, A. R.

S. O’Keeffe, D. McCarthy, P. Woulfe, M. W. Grattan, A. R. Hounsell, D. Sporea, L. Mihai, I. Vata, G. Leen, and E. Lewis, “A review of recent advances in optical fiber sensors for in vivo dosimetry during radiotherapy,” Br. J. Radiol. 88(1050), 20140702 (2015).
[Crossref]

Huq, M. S.

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. S. Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

Ibbott, G.

F. Mourtada, J. Mikell, and G. Ibbott, “Monte Carlo calculations of AAPM Task Group Report No. 43 dosimetry parameters for the (125)I I-Seed AgX100 source model,” Brachytherapy 11(3), 237–244 (2012).
[Crossref]

Ibbott, G. S.

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. Saiful Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. S. Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

Keeffe, S. O.

P. Woulfe, S. O. Keeffe, D. McCarthy, M. Grattan, A. Hounsell, J. Cronin, and E. Lewis, “Characterisation of radioluminesence based optical fiber dosimeter in radiotherapy beam applications,” in SENSORS, 2013 IEEE, (2013), 1–4.

Kertzscher, G.

G. Kertzscher, A. Rosenfeld, S. Beddar, K. Tanderup, and J. E. Cygler, “In vivo dosimetry: trends and prospects for brachytherapy,” Br. J. Radiol. 87(1041), 20140206 (2014).
[Crossref]

K. Tanderup, S. Beddar, C. E. Andersen, G. Kertzscher, and J. E. Cygler, “In vivo dosimetry in brachytherapy,” Med. Phys. 40(7), 070902 (2013).
[Crossref]

G. Kertzscher, C. E. Andersen, F. A. Siebert, S. K. Nielsen, J. C. Lindegaard, and K. Tanderup, “Identifying afterloading PDR and HDR brachytherapy errors using real-time fiber-coupled Al(2)O(3):C dosimetry and a novel statistical error decision criterion,” Radiother. Oncol. 100(3), 456–462 (2011).
[Crossref]

Kirisits, C.

C. Kirisits, F.-A. Siebert, D. Baltas, M. De Brabandere, T. P. Hellebust, D. Berger, and J. Venselaar, “Accuracy of volume and DVH parameters determined with different brachytherapy treatment planning systems,” Radiother. Oncol. 84(3), 290–297 (2007).
[Crossref]

Knoos, T.

J. Cunningham, M. Coffey, T. Knoos, and O. Holmberg, “Radiation Oncology Safety Information System (ROSIS)–profiles of participants and the first 1074 incident reports,” Radiother. Oncol. 97(3), 601–607 (2010).
[Crossref]

Leen, G.

S. O’Keeffe, D. McCarthy, P. Woulfe, M. W. Grattan, A. R. Hounsell, D. Sporea, L. Mihai, I. Vata, G. Leen, and E. Lewis, “A review of recent advances in optical fiber sensors for in vivo dosimetry during radiotherapy,” Br. J. Radiol. 88(1050), 20140702 (2015).
[Crossref]

Lewis, E.

S. O’Keeffe, D. McCarthy, P. Woulfe, M. W. Grattan, A. R. Hounsell, D. Sporea, L. Mihai, I. Vata, G. Leen, and E. Lewis, “A review of recent advances in optical fiber sensors for in vivo dosimetry during radiotherapy,” Br. J. Radiol. 88(1050), 20140702 (2015).
[Crossref]

P. Woulfe, S. O. Keeffe, D. McCarthy, M. Grattan, A. Hounsell, J. Cronin, and E. Lewis, “Characterisation of radioluminesence based optical fiber dosimeter in radiotherapy beam applications,” in SENSORS, 2013 IEEE, (2013), 1–4.

P. Woulfe, F. J. Sullivan, E. Lewis, and S. O’Keeffe, “Plastic optical fiber sensor for in-vivo radiation monitoring during brachytherapy,” in 4th International Conference on Optical Fiber Sensors (2015).

Lindegaard, J. C.

G. Kertzscher, C. E. Andersen, F. A. Siebert, S. K. Nielsen, J. C. Lindegaard, and K. Tanderup, “Identifying afterloading PDR and HDR brachytherapy errors using real-time fiber-coupled Al(2)O(3):C dosimetry and a novel statistical error decision criterion,” Radiother. Oncol. 100(3), 456–462 (2011).
[Crossref]

Lockhart, J. L.

S. G. Moreira, J. D. Seigne, R. C. Ordorica, J. M. Pow-Sang, and J. L. Lockhart, “2004: Devastating Complications following Brachytherapy in the Treatment of Prostate Adenocarcinoma,” J. Urol. 171(4S), 283 (2004).
[Crossref]

Malone, J.

O. Holmberg, J. Malone, M. Rehani, D. McLean, and R. Czarwinski, “Current issues and actions in radiation protection of patients,” Eur. J. Radiol. 76(1), 15–19 (2010).
[Crossref]

McCarthy, D.

S. O’Keeffe, D. McCarthy, P. Woulfe, M. W. Grattan, A. R. Hounsell, D. Sporea, L. Mihai, I. Vata, G. Leen, and E. Lewis, “A review of recent advances in optical fiber sensors for in vivo dosimetry during radiotherapy,” Br. J. Radiol. 88(1050), 20140702 (2015).
[Crossref]

P. Woulfe, S. O. Keeffe, D. McCarthy, M. Grattan, A. Hounsell, J. Cronin, and E. Lewis, “Characterisation of radioluminesence based optical fiber dosimeter in radiotherapy beam applications,” in SENSORS, 2013 IEEE, (2013), 1–4.

McLean, D.

O. Holmberg, J. Malone, M. Rehani, D. McLean, and R. Czarwinski, “Current issues and actions in radiation protection of patients,” Eur. J. Radiol. 76(1), 15–19 (2010).
[Crossref]

Mihai, L.

S. O’Keeffe, D. McCarthy, P. Woulfe, M. W. Grattan, A. R. Hounsell, D. Sporea, L. Mihai, I. Vata, G. Leen, and E. Lewis, “A review of recent advances in optical fiber sensors for in vivo dosimetry during radiotherapy,” Br. J. Radiol. 88(1050), 20140702 (2015).
[Crossref]

Mikell, J.

F. Mourtada, J. Mikell, and G. Ibbott, “Monte Carlo calculations of AAPM Task Group Report No. 43 dosimetry parameters for the (125)I I-Seed AgX100 source model,” Brachytherapy 11(3), 237–244 (2012).
[Crossref]

Mitch, M. G.

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. Saiful Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. S. Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

Moreira, S. G.

S. G. Moreira, J. D. Seigne, R. C. Ordorica, J. M. Pow-Sang, and J. L. Lockhart, “2004: Devastating Complications following Brachytherapy in the Treatment of Prostate Adenocarcinoma,” J. Urol. 171(4S), 283 (2004).
[Crossref]

Mourtada, F.

F. Mourtada, J. Mikell, and G. Ibbott, “Monte Carlo calculations of AAPM Task Group Report No. 43 dosimetry parameters for the (125)I I-Seed AgX100 source model,” Brachytherapy 11(3), 237–244 (2012).
[Crossref]

L. Beaulieu, Å. Carlsson Tedgren, J.-F. Carrier, S. D. Davis, F. Mourtada, M. J. Rivard, R. M. Thomson, F. Verhaegen, T. A. Wareing, and J. F. Williamson, “Report of the Task Group 186 on model-based dose calculation methods in brachytherapy beyond the TG-43 formalism: Current status and recommendations for clinical implementation,” Med. Phys. 39(10), 6208–6236 (2012).
[Crossref]

Nath, R.

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. Saiful Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. S. Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

Nenot, J. C.

V. Chambrette, S. Hardy, and J. C. Nenot, “Radiological accidents Database establishment “ACCIRAD” at IPSN,” Radioprotection 36(4), 477–510 (2001).
[Crossref]

Nielsen, S. K.

G. Kertzscher, C. E. Andersen, F. A. Siebert, S. K. Nielsen, J. C. Lindegaard, and K. Tanderup, “Identifying afterloading PDR and HDR brachytherapy errors using real-time fiber-coupled Al(2)O(3):C dosimetry and a novel statistical error decision criterion,” Radiother. Oncol. 100(3), 456–462 (2011).
[Crossref]

O’Keeffe, S.

P. Woulfe, S. O’Keeffe, and F. J. Sullivan, “EP-1800: Optical Fiber Luminescence Sensor for Real-time LDR Brachytherapy Dosimetry,” Radiother. Oncol. 123, S988–S989 (2017).
[Crossref]

S. O’Keeffe, D. McCarthy, P. Woulfe, M. W. Grattan, A. R. Hounsell, D. Sporea, L. Mihai, I. Vata, G. Leen, and E. Lewis, “A review of recent advances in optical fiber sensors for in vivo dosimetry during radiotherapy,” Br. J. Radiol. 88(1050), 20140702 (2015).
[Crossref]

P. Woulfe, F. J. Sullivan, E. Lewis, and S. O’Keeffe, “Plastic optical fiber sensor for in-vivo radiation monitoring during brachytherapy,” in 4th International Conference on Optical Fiber Sensors (2015).

P. Woulfe, F. Sullivan, and S. O’Keeffe, “LYSO-based optical fiber luminescence sensor for real-time LDR brachytherapy dosimetry,” SPIE Photonics Europe (SPIE, 2018), Vol. 10680.

Ordorica, R. C.

S. G. Moreira, J. D. Seigne, R. C. Ordorica, J. M. Pow-Sang, and J. L. Lockhart, “2004: Devastating Complications following Brachytherapy in the Treatment of Prostate Adenocarcinoma,” J. Urol. 171(4S), 283 (2004).
[Crossref]

Pow-Sang, J. M.

S. G. Moreira, J. D. Seigne, R. C. Ordorica, J. M. Pow-Sang, and J. L. Lockhart, “2004: Devastating Complications following Brachytherapy in the Treatment of Prostate Adenocarcinoma,” J. Urol. 171(4S), 283 (2004).
[Crossref]

Rehani, M.

O. Holmberg, J. Malone, M. Rehani, D. McLean, and R. Czarwinski, “Current issues and actions in radiation protection of patients,” Eur. J. Radiol. 76(1), 15–19 (2010).
[Crossref]

Rivard, M. J.

L. Beaulieu, Å. Carlsson Tedgren, J.-F. Carrier, S. D. Davis, F. Mourtada, M. J. Rivard, R. M. Thomson, F. Verhaegen, T. A. Wareing, and J. F. Williamson, “Report of the Task Group 186 on model-based dose calculation methods in brachytherapy beyond the TG-43 formalism: Current status and recommendations for clinical implementation,” Med. Phys. 39(10), 6208–6236 (2012).
[Crossref]

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. Saiful Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. S. Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

Rosenfeld, A.

G. Kertzscher, A. Rosenfeld, S. Beddar, K. Tanderup, and J. E. Cygler, “In vivo dosimetry: trends and prospects for brachytherapy,” Br. J. Radiol. 87(1041), 20140206 (2014).
[Crossref]

Saiful Huq, M.

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. Saiful Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

Seigne, J. D.

S. G. Moreira, J. D. Seigne, R. C. Ordorica, J. M. Pow-Sang, and J. L. Lockhart, “2004: Devastating Complications following Brachytherapy in the Treatment of Prostate Adenocarcinoma,” J. Urol. 171(4S), 283 (2004).
[Crossref]

Siebert, F. A.

G. Kertzscher, C. E. Andersen, F. A. Siebert, S. K. Nielsen, J. C. Lindegaard, and K. Tanderup, “Identifying afterloading PDR and HDR brachytherapy errors using real-time fiber-coupled Al(2)O(3):C dosimetry and a novel statistical error decision criterion,” Radiother. Oncol. 100(3), 456–462 (2011).
[Crossref]

Siebert, F.-A.

C. Kirisits, F.-A. Siebert, D. Baltas, M. De Brabandere, T. P. Hellebust, D. Berger, and J. Venselaar, “Accuracy of volume and DVH parameters determined with different brachytherapy treatment planning systems,” Radiother. Oncol. 84(3), 290–297 (2007).
[Crossref]

Sporea, D.

S. O’Keeffe, D. McCarthy, P. Woulfe, M. W. Grattan, A. R. Hounsell, D. Sporea, L. Mihai, I. Vata, G. Leen, and E. Lewis, “A review of recent advances in optical fiber sensors for in vivo dosimetry during radiotherapy,” Br. J. Radiol. 88(1050), 20140702 (2015).
[Crossref]

Strohmaier, S.

S. Strohmaier and G. Zwierzchowski, “Comparison of (60)Co and (192)Ir sources in HDR brachytherapy,” J. Contemp. Brachytherapy 4, 199–208 (2011).
[Crossref]

Sullivan, F.

P. Woulfe, F. Sullivan, and S. O’Keeffe, “LYSO-based optical fiber luminescence sensor for real-time LDR brachytherapy dosimetry,” SPIE Photonics Europe (SPIE, 2018), Vol. 10680.

Sullivan, F. J.

P. Woulfe, S. O’Keeffe, and F. J. Sullivan, “EP-1800: Optical Fiber Luminescence Sensor for Real-time LDR Brachytherapy Dosimetry,” Radiother. Oncol. 123, S988–S989 (2017).
[Crossref]

P. Woulfe, F. J. Sullivan, E. Lewis, and S. O’Keeffe, “Plastic optical fiber sensor for in-vivo radiation monitoring during brachytherapy,” in 4th International Conference on Optical Fiber Sensors (2015).

Tanderup, K.

G. Kertzscher, A. Rosenfeld, S. Beddar, K. Tanderup, and J. E. Cygler, “In vivo dosimetry: trends and prospects for brachytherapy,” Br. J. Radiol. 87(1041), 20140206 (2014).
[Crossref]

K. Tanderup, S. Beddar, C. E. Andersen, G. Kertzscher, and J. E. Cygler, “In vivo dosimetry in brachytherapy,” Med. Phys. 40(7), 070902 (2013).
[Crossref]

G. Kertzscher, C. E. Andersen, F. A. Siebert, S. K. Nielsen, J. C. Lindegaard, and K. Tanderup, “Identifying afterloading PDR and HDR brachytherapy errors using real-time fiber-coupled Al(2)O(3):C dosimetry and a novel statistical error decision criterion,” Radiother. Oncol. 100(3), 456–462 (2011).
[Crossref]

Thomson, R. M.

L. Beaulieu, Å. Carlsson Tedgren, J.-F. Carrier, S. D. Davis, F. Mourtada, M. J. Rivard, R. M. Thomson, F. Verhaegen, T. A. Wareing, and J. F. Williamson, “Report of the Task Group 186 on model-based dose calculation methods in brachytherapy beyond the TG-43 formalism: Current status and recommendations for clinical implementation,” Med. Phys. 39(10), 6208–6236 (2012).
[Crossref]

Valentin, J.

J. Valentin, “Preface, Main Points, Introduction, Chapters 2 and 3,” Ann. ICRP 35(2), 1–9 (2005).
[Crossref]

J. Valentin, Prevention of accidents to patients undergoing radiation therapy. ICRP Publication 86 (2007), Vol. 30, pp. 1–70.

Vata, I.

S. O’Keeffe, D. McCarthy, P. Woulfe, M. W. Grattan, A. R. Hounsell, D. Sporea, L. Mihai, I. Vata, G. Leen, and E. Lewis, “A review of recent advances in optical fiber sensors for in vivo dosimetry during radiotherapy,” Br. J. Radiol. 88(1050), 20140702 (2015).
[Crossref]

Venselaar, J.

C. Kirisits, F.-A. Siebert, D. Baltas, M. De Brabandere, T. P. Hellebust, D. Berger, and J. Venselaar, “Accuracy of volume and DVH parameters determined with different brachytherapy treatment planning systems,” Radiother. Oncol. 84(3), 290–297 (2007).
[Crossref]

Verhaegen, F.

L. Beaulieu, Å. Carlsson Tedgren, J.-F. Carrier, S. D. Davis, F. Mourtada, M. J. Rivard, R. M. Thomson, F. Verhaegen, T. A. Wareing, and J. F. Williamson, “Report of the Task Group 186 on model-based dose calculation methods in brachytherapy beyond the TG-43 formalism: Current status and recommendations for clinical implementation,” Med. Phys. 39(10), 6208–6236 (2012).
[Crossref]

Wareing, T. A.

L. Beaulieu, Å. Carlsson Tedgren, J.-F. Carrier, S. D. Davis, F. Mourtada, M. J. Rivard, R. M. Thomson, F. Verhaegen, T. A. Wareing, and J. F. Williamson, “Report of the Task Group 186 on model-based dose calculation methods in brachytherapy beyond the TG-43 formalism: Current status and recommendations for clinical implementation,” Med. Phys. 39(10), 6208–6236 (2012).
[Crossref]

Williamson, J. F.

L. Beaulieu, Å. Carlsson Tedgren, J.-F. Carrier, S. D. Davis, F. Mourtada, M. J. Rivard, R. M. Thomson, F. Verhaegen, T. A. Wareing, and J. F. Williamson, “Report of the Task Group 186 on model-based dose calculation methods in brachytherapy beyond the TG-43 formalism: Current status and recommendations for clinical implementation,” Med. Phys. 39(10), 6208–6236 (2012).
[Crossref]

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. Saiful Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. S. Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

Woulfe, P.

P. Woulfe, S. O’Keeffe, and F. J. Sullivan, “EP-1800: Optical Fiber Luminescence Sensor for Real-time LDR Brachytherapy Dosimetry,” Radiother. Oncol. 123, S988–S989 (2017).
[Crossref]

S. O’Keeffe, D. McCarthy, P. Woulfe, M. W. Grattan, A. R. Hounsell, D. Sporea, L. Mihai, I. Vata, G. Leen, and E. Lewis, “A review of recent advances in optical fiber sensors for in vivo dosimetry during radiotherapy,” Br. J. Radiol. 88(1050), 20140702 (2015).
[Crossref]

P. Woulfe, S. O. Keeffe, D. McCarthy, M. Grattan, A. Hounsell, J. Cronin, and E. Lewis, “Characterisation of radioluminesence based optical fiber dosimeter in radiotherapy beam applications,” in SENSORS, 2013 IEEE, (2013), 1–4.

P. Woulfe, F. J. Sullivan, E. Lewis, and S. O’Keeffe, “Plastic optical fiber sensor for in-vivo radiation monitoring during brachytherapy,” in 4th International Conference on Optical Fiber Sensors (2015).

P. Woulfe, F. Sullivan, and S. O’Keeffe, “LYSO-based optical fiber luminescence sensor for real-time LDR brachytherapy dosimetry,” SPIE Photonics Europe (SPIE, 2018), Vol. 10680.

Yashar, C. M.

C. M. Yashar, “23 - Basic Principles in Gynecologic Radiotherapy,” in Clinical Gynecologic Oncology (Ninth Edition), P. J. DiSaia, W. T. Creasman, R. S. Mannel, D. S. McMeekin, and D. G. Mutch, eds. (Elsevier, 2018), pp. 586–605.e583.

Zwierzchowski, G.

S. Strohmaier and G. Zwierzchowski, “Comparison of (60)Co and (192)Ir sources in HDR brachytherapy,” J. Contemp. Brachytherapy 4, 199–208 (2011).
[Crossref]

Ann. ICRP (1)

J. Valentin, “Preface, Main Points, Introduction, Chapters 2 and 3,” Ann. ICRP 35(2), 1–9 (2005).
[Crossref]

Br. J. Radiol. (2)

G. Kertzscher, A. Rosenfeld, S. Beddar, K. Tanderup, and J. E. Cygler, “In vivo dosimetry: trends and prospects for brachytherapy,” Br. J. Radiol. 87(1041), 20140206 (2014).
[Crossref]

S. O’Keeffe, D. McCarthy, P. Woulfe, M. W. Grattan, A. R. Hounsell, D. Sporea, L. Mihai, I. Vata, G. Leen, and E. Lewis, “A review of recent advances in optical fiber sensors for in vivo dosimetry during radiotherapy,” Br. J. Radiol. 88(1050), 20140702 (2015).
[Crossref]

Brachytherapy (1)

F. Mourtada, J. Mikell, and G. Ibbott, “Monte Carlo calculations of AAPM Task Group Report No. 43 dosimetry parameters for the (125)I I-Seed AgX100 source model,” Brachytherapy 11(3), 237–244 (2012).
[Crossref]

Eur. J. Radiol. (1)

O. Holmberg, J. Malone, M. Rehani, D. McLean, and R. Czarwinski, “Current issues and actions in radiation protection of patients,” Eur. J. Radiol. 76(1), 15–19 (2010).
[Crossref]

J. Contemp. Brachytherapy (1)

S. Strohmaier and G. Zwierzchowski, “Comparison of (60)Co and (192)Ir sources in HDR brachytherapy,” J. Contemp. Brachytherapy 4, 199–208 (2011).
[Crossref]

J. Urol. (1)

S. G. Moreira, J. D. Seigne, R. C. Ordorica, J. M. Pow-Sang, and J. L. Lockhart, “2004: Devastating Complications following Brachytherapy in the Treatment of Prostate Adenocarcinoma,” J. Urol. 171(4S), 283 (2004).
[Crossref]

Med. Phys. (4)

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. S. Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

L. Beaulieu, Å. Carlsson Tedgren, J.-F. Carrier, S. D. Davis, F. Mourtada, M. J. Rivard, R. M. Thomson, F. Verhaegen, T. A. Wareing, and J. F. Williamson, “Report of the Task Group 186 on model-based dose calculation methods in brachytherapy beyond the TG-43 formalism: Current status and recommendations for clinical implementation,” Med. Phys. 39(10), 6208–6236 (2012).
[Crossref]

K. Tanderup, S. Beddar, C. E. Andersen, G. Kertzscher, and J. E. Cygler, “In vivo dosimetry in brachytherapy,” Med. Phys. 40(7), 070902 (2013).
[Crossref]

M. J. Rivard, B. M. Coursey, L. A. DeWerd, W. F. Hanson, M. Saiful Huq, G. S. Ibbott, M. G. Mitch, R. Nath, and J. F. Williamson, “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med. Phys. 31(3), 633–674 (2004).
[Crossref]

Radioprotection (1)

V. Chambrette, S. Hardy, and J. C. Nenot, “Radiological accidents Database establishment “ACCIRAD” at IPSN,” Radioprotection 36(4), 477–510 (2001).
[Crossref]

Radiother. Oncol. (4)

G. Kertzscher, C. E. Andersen, F. A. Siebert, S. K. Nielsen, J. C. Lindegaard, and K. Tanderup, “Identifying afterloading PDR and HDR brachytherapy errors using real-time fiber-coupled Al(2)O(3):C dosimetry and a novel statistical error decision criterion,” Radiother. Oncol. 100(3), 456–462 (2011).
[Crossref]

J. Cunningham, M. Coffey, T. Knoos, and O. Holmberg, “Radiation Oncology Safety Information System (ROSIS)–profiles of participants and the first 1074 incident reports,” Radiother. Oncol. 97(3), 601–607 (2010).
[Crossref]

C. Kirisits, F.-A. Siebert, D. Baltas, M. De Brabandere, T. P. Hellebust, D. Berger, and J. Venselaar, “Accuracy of volume and DVH parameters determined with different brachytherapy treatment planning systems,” Radiother. Oncol. 84(3), 290–297 (2007).
[Crossref]

P. Woulfe, S. O’Keeffe, and F. J. Sullivan, “EP-1800: Optical Fiber Luminescence Sensor for Real-time LDR Brachytherapy Dosimetry,” Radiother. Oncol. 123, S988–S989 (2017).
[Crossref]

Other (7)

P. Woulfe, F. Sullivan, and S. O’Keeffe, “LYSO-based optical fiber luminescence sensor for real-time LDR brachytherapy dosimetry,” SPIE Photonics Europe (SPIE, 2018), Vol. 10680.

Hamamatsu Photonics K. K, https://www.hamamatsu.com , last accessed January 2018.

P. Woulfe, S. O. Keeffe, D. McCarthy, M. Grattan, A. Hounsell, J. Cronin, and E. Lewis, “Characterisation of radioluminesence based optical fiber dosimeter in radiotherapy beam applications,” in SENSORS, 2013 IEEE, (2013), 1–4.

P. Woulfe, F. J. Sullivan, E. Lewis, and S. O’Keeffe, “Plastic optical fiber sensor for in-vivo radiation monitoring during brachytherapy,” in 4th International Conference on Optical Fiber Sensors (2015).

I. A. E. AGENCY, Lessons Learned from Accidental Exposures in Radiotherapy, Safety Reports Series (International Atomic Energy Agency, Vienna, 2000).

C. M. Yashar, “23 - Basic Principles in Gynecologic Radiotherapy,” in Clinical Gynecologic Oncology (Ninth Edition), P. J. DiSaia, W. T. Creasman, R. S. Mannel, D. S. McMeekin, and D. G. Mutch, eds. (Elsevier, 2018), pp. 586–605.e583.

J. Valentin, Prevention of accidents to patients undergoing radiation therapy. ICRP Publication 86 (2007), Vol. 30, pp. 1–70.

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Figures (11)

Fig. 1.
Fig. 1. Optical fiber based radiation dosimeter.
Fig. 2.
Fig. 2. Assembly to insert scintillating phosphor.
Fig. 3.
Fig. 3. Optical fiber sensor within brachytherapy needle for direct tumour dose monitoring.
Fig. 4.
Fig. 4. Coordinate system used for brachytherapy dosimetry calculations [23].
Fig. 5.
Fig. 5. Optical fiber sensor within brachytherapy needle and located within the novel prostate phantom.
Fig. 6.
Fig. 6. Repeatability of 0.361mCi Seed with Gd2O2S:Tb Dosimeter.
Fig. 7.
Fig. 7. Various positions of 0.361mCi seed with Gd2O2S:Tb Dosimeter.
Fig. 8.
Fig. 8. (a) Sensor response at different distances from the radiation source (b) Photon counts as a function of the distance from the source, demonstrating the inverse-square relationship.
Fig. 9.
Fig. 9. Treatment Planning System (TPS) indicating Point Dose Expected TPS Values (Gy).
Fig. 10.
Fig. 10. Response of the Optical Fiber Sensor to I-125 seeds ranging from 0.361mCi up to 2.888mCi.
Fig. 11.
Fig. 11. Comparison of Dosimeter to TG 43.

Equations (1)

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D ( r ) = S k Λ G L ( r , θ 0 ) G L ( r 0 , θ 0 ) g L ( r ) ϕ a n ( r )

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