Abstract

Functionalized gold nanoparticles (GNPs) with controlled geometrical and optical properties have been the subject of intense research and biomedical applications. This review summarizes recent data and topical problems in nanomedicine that are related to the use of variously sized, shaped, and structured GNPs. We focus on three topical fields in current nanomedicine: (1) use of GNP-based nanoplatforms for the targeted delivery of anticancer and antimicrobial drugs and of genes; (2) GNP-based cancer immunotherapy; and (3) combined chemo-, immuno-, and phototherapy. We present a summary of the available literature data and a short discussion of future work.

© 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

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2019 (25)

K. Sztandera, M. Gorzkiewicz, and B. Klajnert-Maculewicz, “Gold nanoparticles in cancer treatment,” Mol. Pharm. 16(1), 1–23 (2019).
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L. A. Dykman and N. G. Khlebtsov, “Methods for chemical synthesis of colloidal gold,” Russ. Chem. Rev. 88(3), 229–247 (2019).
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J. B. Vines, J.-H. Yoon, N.-E. Ryu, D.-J. Lim, and H. Park, “Gold nanoparticles for photothermal cancer therapy,” Front Chem. 7, 167 (2019).
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A. Amini, M. Kamali, B. Amini, and A. Najafi, “Enhanced antibacterial activity of imipenem-immobilized on surface of spherical and rod gold nanoparticles,” J. Phys. D 52(6), 065401 (2019).
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S. Hayat, S. Muzammil, B. Shabana, B. Aslam, M. H. Siddique, M. Saqalein, and M. A. Nisar, “Quorum quenching: role of nanoparticles as signal jammers in Gram-negative bacteria,” Future Microbiol. 14(1), 61–72 (2019).
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V. K. Sonu, I. Rajkumar, K. Bhattacharjee, S. R. Joshi, and S. Mitra, “Interaction of caffeine and sulfadiazine with lysozyme adsorbed at colloidal metal nanoparticle interface: influence on drug transport ability and antibacterial activity,” J. Biomol. Struct. Dyn. 37(2), 321–335 (2019).
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D. A. Gonzalez-Carter, Z. Y. Ong, C. M. McGilvery, I. E. Dunlop, D. T. Dexter, and A. E. Porter, “L-DOPA functionalized, multi-branched gold nanoparticles as brain-targeted nano-vehicles,” Nanomedicine (Lond.) 15(1), 1–11 (2019).
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D. Zhang, J. Zhang, J. Zeng, Z. Li, H. Zuo, C. Huang, and X. Zhao, “Nano-gold loaded with resveratrol enhance the anti-hepatoma effect of resveratrol in vitro and in vivo,” J. Biomed. Nanotechnol. 15(2), 288–300 (2019).
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A. Artiga, I. Serrano-Sevilla, L. De Matteis, S. G. Mitchell, and J. M. de la Fuente, “Current status and future perspectives of gold nanoparticle vectors for siRNA delivery,” J. Mater. Chem. B Mater. Biol. Med. 7(6), 876–896 (2019).
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E. Morgan, D. Wupperfeld, D. Morales, and N. Reich, “Shape matters: Gold nanoparticle shape impacts the biological activity of siRNA delivery,” Bioconjug. Chem. 30(3), 853–860 (2019).
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T. Pylaev, E. Vanzha, E. Avdeeva, B. Khlebtsov, and N. Khlebtsov, “A novel cell transfection platform based on laser optoporation mediated by Au nanostar layers,” J. Biophotonics 12(1), e201800166 (2019).
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S. K. Vemuri, R. R. Banala, S. Mukherjee, P. Uppula, G Subbaiah, R.G.V Gurava, and T. Malarvilli, “Novel biosynthesized gold nanoparticles as anti-cancer agents against breast cancer: Synthesis, biological evaluation, molecular modelling studies,” Mater. Sci. Eng. C 99, 417–429 (2019).
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Q. You, X. Zhang, F.-G. Wu, and Y. Chen, “Colorimetric and test stripe-based assay of bacteria by using vancomycin-modified gold nanoparticles,” Sens. Actuators B Chem. 281, 408–414 (2019).
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M. B. Haddada, K. Jeannot, and J. Spadavecchia, “Novel synthesis and characterization of doxycycline-loaded gold nanoparticles: the golden doxycycline for antibacterial applications,” Part. Part. Syst. Charact. 36(2), 1800395 (2019).
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A. Anwar, R. Siddiqui, M. Raza Shah, and N. Ahmed Khan, “Gold nanoparticles conjugation enhances antiacanthamoebic properties of nystatin, fluconazole and amphotericin B,” J. Microbiol. Biotechnol. 29(1), 171–177 (2019).
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B. Englinger, C. Pirker, P. Heffeter, A. Terenzi, C. R. Kowol, B. K. Keppler, and W. Berger, “Metal drugs and the anticancer immune response,” Chem. Rev. 119(2), 1519–1624 (2019).
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F. Lopez-Campos, D. Candini, E. Carrasco, and M. A. Berenguer Francés, “Nanoparticles applied to cancer immunoregulation,” Rep. Pract. Oncol. Radiother. 24(1), 47–55 (2019).
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Q.-V. Le, G. Yang, Y. Wu, H. W. Jang, M. Shokouhimehr, and Y.-K. Oh, “Nanomaterials for modulating innate immune cells in cancer immunotherapy,” Asian J. Pharm. Sci. 14(1), 16–29 (2019).
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I. Mottas, A. Bekdemir, A. Cereghetti, L. Spagnuolo, Y.-S. S. Yang, M. Müller, D. J. Irvine, F. Stellacci, and C. Bourquin, “Amphiphilic nanoparticle delivery enhances the anticancer efficacy of a TLR7 ligand via local immune activation,” Biomaterials 190-191, 111–120 (2019).
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Y. Li, X. Li, F. Zhou, A. Doughty, A. R. Hoover, R. E. Nordquist, and W. R. Chen, “Nanotechnology-based photoimmunological therapies for cancer,” Cancer Lett. 442, 429–438 (2019).
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J. Beik, M. Khateri, Z. Khosravi, S. K. Kamrava, S. Kooranifar, H. Ghaznavi, and A. Shakeri-Zadeh, “Gold nanoparticles in combinatorial cancer therapy strategies,” Coord. Chem. Rev. 387, 299–324 (2019).
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Y. Zhao, Q. Guo, X. Dai, X. Wei, Y. Yu, X. Chen, C. Li, Z. Cao, and X. Zhang, “A biomimetic non-antibiotic approach to eradicate drug-resistant infections,” Adv. Mater. 31(7), e1806024 (2019).
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G. Su, D. Miao, Y. Yu, M. Zhou, P. Jiao, X. Cao, B. Yan, and H. Zhu, “Mesoporous silica-coated gold nanostars with drug payload for combined chemo-photothermal cancer therapy,” J. Drug Target. 27(2), 201–210 (2019).
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F. Peng, M. I. Setyawati, J. K. Tee, X. Ding, J. Wang, M. E. Nga, H. K. Ho, and D. T. Leong, “Nanoparticles promote in vivo breast cancer cell intravasation and extravasation by inducing endothelial leakiness,” Nat. Nanotechnol. 14(3), 279–286 (2019).
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B. N. Khlebtsov, D. N. Bratashov, N. A. Byzova, B. B. Dzantiev, and N. G. Khlebtsov, “SERS-based lateral flow immunoassay of troponin I using gap-enhanced Raman tags,” Nano Res. 12(2), 413–420 (2019).
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2018 (43)

T. Ramasamy, H. B. Ruttala, P. Sundaramoorthy, B. K. Poudel, Y. S. Youn, S. K. Ku, H.-G. Choi, C. S. Yong, and J. O. Kim, “Multimodal selenium nanoshell-capped Au@mSiO2 nanoplatform for NIR-responsive chemo-photothermal therapy against metastatic breast cancer,” NPG Asia Mater. 10(4), 197–216 (2018).
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L. Xu, J. Liu, J. Xi, Q. Li, B. Chang, X. Duan, G. Wang, S. Wang, Z. Wang, and L. Wang, “Synergized multimodal therapy for safe and effective reversal of cancer multidrug resistance based on low-level photothermal and photodynamic effects,” Small 14(31), e1800785 (2018).
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Y. Li, D. He, J. Tu, R. Wang, C. Zu, Y. Chen, W. Yang, D. Shi, T. J. Webster, and Y. Shen, “The comparative effect of wrapping solid gold nanoparticles and hollow gold nanoparticles with doxorubicin-loaded thermosensitive liposomes for cancer thermo-chemotherapy,” Nanoscale 10(18), 8628–8641 (2018).
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S. C.-H. Tsao, J. Wang, Y. Wang, A. Behren, J. Cebon, and M. Trau, “Characterising the phenotypic evolution of circulating tumour cells during treatment,” Nat. Commun. 9(1), 1482 (2018).
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D. G. Meeker, T. Wang, W. N. Harrington, V. P. Zharov, S. A. Johnson, S. V. Jenkins, S. E. Oyibo, C. M. Walker, W. B. Mills, M. E. Shirtliff, K. E. Beenken, J. Chen, and M. S. Smeltzer, “Versatility of targeted antibiotic-loaded gold nanoconstructs for the treatment of biofilm-associated bacterial infections,” Int. J. Hyperthermia 34(2), 209–219 (2018).
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Q. Chen, L. Zhang, Y. Feng, F. Shi, Y. Wang, P. Wang, and L. Liu, “Dual-functional peptide conjugated gold nanorods for the detection and photothermal ablation of pathogenic bacteria,” J. Mater. Chem. B Mater. Biol. Med. 6(46), 7643–7651 (2018).
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N. Li, J. Cheng, Y. Zhang, J. Wang, G. Huang, J. Zhu, and D. He, “A chemophotothermal and targeting multifunctional nanoprobe with a tumor-diagnosing ability,” Nano Res. 11(8), 4333–4347 (2018).
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J. Nam, S. Son, L. J. Ochyl, R. Kuai, A. Schwendeman, and J. J. Moon, “Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer,” Nat. Commun. 9(1), 1074 (2018).
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L. Liu, H. J. Xie, L. M. Mu, R. Liu, Z. B. Su, Y. N. Cui, Y. Xie, and W. L. Lu, “Functional chlorin gold nanorods enable to treat breast cancer by photothermal/photodynamic therapy,” Int. J. Nanomedicine 13(13), 8119–8135 (2018).
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F. Cao, M. Yan, Y. Liu, L. Liu, and G. Ma, “Photothermally controlled MHC class I restricted CD8+ T-cell responses elicited by hyaluronic acid decorated gold nanoparticles as a vaccine for cancer immunotherapy,” Adv. Healthc. Mater. 7(10), e1701439 (2018).
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B. Zhou, J. Song, M. Wang, X. Wang, J. Wang, E. W. Howard, F. Zhou, J. Qu, and W. R. Chen, “BSA-bioinspired gold nanorods loaded with immunoadjuvant for the treatment of melanoma by combined photothermal therapy and immunotherapy,” Nanoscale 10(46), 21640–21647 (2018).
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J. Chen, L. Lin, N. Yan, Y. Hu, H. Fang, Z. Guo, P. Sun, H. Tian, and X. Chen, “Macrophages loaded CpG and GNR-PEI for combination of tumor photothermal therapy and immunotherapy,” Sci. China Mater. 61(11), 1484–1494 (2018).
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R. P. M. Dings, M. Cannon, and K. B. Vang, “Design of gold nanoparticles in dendritic cell-based vaccines,” Part. Part. Syst. Charact. 35(9), 1800109 (2018).
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X. Wang, J. Li, N. Kawazoe, and G. Chen, “Photothermal ablation of cancer cells by albumin-modified gold nanorods and activation of dendritic cells,” Materials (Basel) 12(1), 31 (2018).
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Y. Tian, R. Guo, and W. Yang, “Multifunctional nanotherapeutics for photothermal combination therapy of cancer,” Adv. Ther. 1(8), 1800049 (2018).
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Y. Liu, B. M. Crawford, and T. Vo-Dinh, “Gold nanoparticles-mediated photothermal therapy and immunotherapy,” Immunotherapy 10(13), 1175–1188 (2018).
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Y.-S. S. Yang, K. D. Moynihan, A. Bekdemir, T. M. Dichwalkar, M. M. Noh, N. Watson, M. Melo, J. Ingram, H. Suh, H. Ploegh, F. R. Stellacci, and D. J. Irvine, “Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles,” Biomater. Sci. 7(1), 113–124 (2018).
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L. A. Dykman, S. A. Staroverov, A. S. Fomin, V. A. Khanadeev, B. N. Khlebtsov, and V. A. Bogatyrev, “Gold nanoparticles as an adjuvant: Influence of size, shape, and technique of combination with CpG on antibody production,” Int. Immunopharmacol. 54, 163–168 (2018).
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M. J. Silvero C, D. M. Rocca, E. A. de la Villarmois, K. Fournier, A. E. Lanterna, M. F. Pérez, M. C. Becerra, and J. C. Scaiano, “Selective photoinduced antibacterial activity of amoxicillin-coated gold nanoparticles: from one-step synthesis to in vivo cytocompatibility,” ACS Omega 3(1), 1220–1230 (2018).
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S. P. Surendran, M. J. Moon, R. Park, and Y. Y. Jeong, “Bioactive nanoparticles for cancer immunotherapy,” Int. J. Mol. Sci. 19(12), 3877 (2018).
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E. R. Evans, P. Bugga, V. Asthana, and R. Drezek, “Metallic nanoparticles for cancer immunotherapy,” Mater Today (Kidlington) 21(6), 673–685 (2018).
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H. Y. Yoon, S. T. Selvan, Y. Yang, M. J. Kim, D. K. Yi, I. C. Kwon, and K. Kim, “Engineering nanoparticle strategies for effective cancer immunotherapy,” Biomaterials 178, 597–607 (2018).
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R. Mahjub, S. Jatana, S. E. Lee, Z. Qin, G. Pauli, M. Soleimani, S. Madadi, and S.-D. Li, “Recent advances in applying nanotechnologies for cancer immunotherapy,” J. Control. Release 288, 239–263 (2018).
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J. Jia, Y. Zhang, Y. Xin, C. Jiang, B. Yan, and S. Zhai, “Interactions between nanoparticles and dendritic cells: from the perspective of cancer immunotherapy,” Front. Oncol. 8, 404 (2018).
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A. Plan Sangnier, R. Aufaure, L. Motte, C. Wilhelm, E. Guenin, and Y. Lalatonne, “Hybrid Au@alendronate nanoparticles as dual chemo-photothermal agent for combined cancer treatment,” Beilstein J. Nanotechnol. 9, 2947–2952 (2018).
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J. Yu, X. Wang, Y. Li, X. Huang, X. Luo, and X. He, “Synthesis of nerolidol functionalized gold nanoparticles for wound regeneration in people with diabetic foot ulcers in nursing care management,” Sci. Adv. Mater. 10(12), 1775–1781 (2018).
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S. Gurunathan and J.-H. Kim, “Biocompatible gold nanoparticles ameliorate retinoic acid-induced cell death and induce differentiation in F9 teratocarcinoma stem cells,” Nanomaterials (Basel) 8(6), 396 (2018).
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S. Wang, C. Yan, X. Zhang, D. Shi, L. Chi, G. Luo, and J. Deng, “Antimicrobial peptide modification enhances the gene delivery and bactericidal efficiency of gold nanoparticles for accelerating diabetic wound healing,” Biomater. Sci. 6(10), 2757–2772 (2018).
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C. A. Lino, J. C. Harper, J. P. Carney, and J. A. Timlin, “Delivering CRISPR: a review of the challenges and approaches,” Drug Deliv. 25(1), 1234–1257 (2018).
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C. Wang, Y. Wang, L. Zhang, R. J. Miron, J. Liang, M. Shi, W. Mo, S. Zheng, Y. Zhao, and Y. Zhang, “Pretreated macrophage-membrane-coated gold nanocages for precise drug delivery for treatment of bacterial infections,” Adv. Mater. 30(46), e1804023 (2018).
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M. Imran, A. Hameed, R. M. Shafiullah, R. M. Hafizur, I. Ali, T. Roome, and M. R. Shah, “Fabrication of Xanthan stabilized green gold nanoparticles based tolbutamide delivery system for enhanced insulin secretion in mice pancreatic islets,” J. Macromol. Sci. A 55(11–12), 729–735 (2018).
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L. T. Arayan, H. B. Kim, A. W. Bernardo Reyes, N. T. Xuan Huy, I. H. Hong, K. Lee, J.-H. Yeom, Y. Park, and S. Kim, “The immunomodulatory effect of antimicrobial peptide HPA3P restricts Brucella abortus 544 infection in BALB/c mice,” Vet. Microbiol. 225, 17–24 (2018).
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A. K. Singh, X. Bai, M. A. R. Amalaradjou, and A. K. Bhunia, “Antilisterial and antibiofilm activities of Pediocin and LAP functionalized gold nanoparticles,” Front. Sustain. Food Syst. 2, 74 (2018).
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E. de Alteriis, V. Maselli, A. Falanga, S. Galdiero, F. M. Di Lella, R. Gesuele, M. Guida, and E. Galdiero, “Efficiency of gold nanoparticles coated with the antimicrobial peptide indolicidin against biofilm formation and development of Candida spp. clinical isolates,” Infect. Drug Resist. 11(11), 915–925 (2018).
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X. Yang, L. Zhang, and X. Jiang, “Aminosaccharide–gold nanoparticle assemblies as narrow-spectrum antibiotics against methicillin-resistant Staphylococcus aureus,” Nano Res. 11(12), 6237–6243 (2018).
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R. V. Nair, H. Santhakumar, and R. S. Jayasree, “Gold nanorods decorated with a cancer drug for multimodal imaging and therapy,” Faraday Discuss. 207, 423–435 (2018).
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M. U. Farooq, V. Novosad, E. A. Rozhkova, H. Wali, A. Ali, A. A. Fateh, P. B. Neogi, A. Neogi, and Z. Wang, “Gold nanoparticles-enabled efficient dual delivery of anticancer therapeutics to HeLa cells,” Sci. Rep. 8(1), 2907 (2018).
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L. Papaioannou, A. Angelopoulou, S. Hatziantoniou, M. Papadimitriou, P. Apostolou, I. Papasotiriou, and K. Avgoustakis, “Folic acid-functionalized gold nanorods for controlled paclitaxel delivery: in vitro evaluation and cell studies,” AAPS PharmSciTech 20(1), 13 (2018).
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M. Moghiseh, C. Lowe, J. G. Lewis, D. Kumar, A. Butler, N. Anderson, and A. Raja, “Spectral photon-counting molecular imaging for quantification of monoclonal antibody-conjugated gold nanoparticles targeted to lymphoma and breast cancer: an in vitro study,” Contrast Media Mol. Imaging 2018, 2136840 (2018).
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K. Kalimuthu, B.-C. Lubin, A. Bazylevich, G. Gellerman, O. Shpilberg, G. Luboshits, and M. A. Firer, “Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells,” J. Nanobiotechnology 16(1), 34 (2018).
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N. Saadat, F. Liu, B. Haynes, P. Nangia-Makker, X. Bao, J. Li, L. A. Polin, S. Gupta, G. Mao, and M. P. Shekhar, “Nano-targeted delivery of RAD6/translesion synthesis inhibitor for triple negative breast cancer therapy,” Mol. Cancer Ther. 17(12), 2586–2597 (2018).
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H. Norouzi, K. Khoshgard, and F. Akbarzadeh, “In vitro outlook of gold nanoparticles in photo-thermal therapy: a literature review,” Lasers Med. Sci. 33(4), 917–926 (2018).
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D. M. Connor and A. M. Broome, “Gold nanoparticles for the delivery of cancer therapeutics,” Adv. Cancer Res. 139, 163–184 (2018).
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2017 (43)

L. A. Dykman and N. G. Khlebtsov, “Immunological properties of gold nanoparticles,” Chem. Sci. (Camb.) 8(3), 1719–1735 (2017).
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M. R. K. Ali, Y. Wu, D. Ghosh, B. H. Do, K. Chen, M. R. Dawson, N. Fang, T. A. Sulchek, and M. A. El-Sayed, “Nuclear membrane-targeted gold nanoparticles inhibit cancer cell migration and invasion,” ACS Nano 11(4), 3716–3726 (2017).
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S. Iram, M. Zahera, S. Khan, I. Khan, A. Syed, A. A. Ansary, F. Ameen, O. H. M. Shair, and M. S. Khan, “Gold nanoconjugates reinforce the potency of conjugated cisplatin and doxorubicin,” Colloids Surf. B Biointerfaces 160, 254–264 (2017).
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R. Singh, S. Patil, N. Singh, and S. Gupta, “Dual functionality nanobioconjugates targeting intracellular bacteria in cancer cells with enhanced antimicrobial activity,” Sci. Rep. 7(1), 5792 (2017).
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K. O. Shittu, M. T. Bankole, A. S. Abdulkareem, O. K. Abubakre, and A. U. Ubaka, “Application of gold nanoparticles for improved drug efficiency,” Adv. Nat. Sci: Nanosci. Nanotechnol. 8(3), 035014 (2017).
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U. Rajchakit and V. Sarojini, “Recent developments in antimicrobial peptide conjugated gold nanoparticles,” Bioconjug. Chem. 28(11), 2673–2686 (2017).
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R. Jijie, A. Barras, F. Teodorescu, R. Boukherroub, and S. Szunerits, “Advancements on the molecular design of nanoantibiotics: current level of development and future challenges,” Mol. Syst. Des. Eng. 2(4), 349–369 (2017).
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R. Chowdhury, H. Ilyas, A. Ghosh, H. Ali, A. Ghorai, A. Midya, N. R. Jana, S. Das, and A. Bhunia, “Multivalent gold nanoparticle-peptide conjugates for targeting intracellular bacterial infections,” Nanoscale 9(37), 14074–14093 (2017).
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B. Casciaro, M. Moros, S. Rivera-Fernández, A. Bellelli, J. M. de la Fuente, and M. L. Mangoni, “Gold-nanoparticles coated with the antimicrobial peptide esculentin-1a(1-21)NH2 as a reliable strategy for antipseudomonal drugs,” Acta Biomater. 47, 170–181 (2017).
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M. A. Zaimy, N. Saffarzadeh, A. Mohammadi, H. Pourghadamyari, P. Izadi, A. Sarli, L. K. Moghaddam, S. R. Paschepari, H. Azizi, S. Torkamandi, and J. Tavakkoly-Bazzaz, “New methods in the diagnosis of cancer and gene therapy of cancer based on nanoparticles,” Cancer Gene Ther. 24(6), 233–243 (2017).
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R. Mendes, A. R. Fernandes, and P. V. Baptista, “Gold nanoparticle approach to the selective delivery of gene silencing in cancer—the case for combined delivery?” Genes (Basel) 8(3), 94 (2017).
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Z. Glass, Y. Li, and Q. Xu, “Nanoparticles for CRISPR-Cas9 delivery,” Nat. Biomed. Eng. 1(11), 854–855 (2017).
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K. Lee, M. Conboy, H. M. Park, F. Jiang, H. J. Kim, M. A. Dewitt, V. A. Mackley, K. Chang, A. Rao, C. Skinner, T. Shobha, M. Mehdipour, H. Liu, W. C. Huang, F. Lan, N. L. Bray, S. Li, J. E. Corn, K. Kataoka, J. A. Doudna, I. Conboy, and N. Murthy, “Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair,” Nat. Biomed. Eng. 1(11), 889–901 (2017).
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R. Mout, M. Ray, G. Yesilbag Tonga, Y. W. Lee, T. Tay, K. Sasaki, and V. M. Rotello, “Direct cytosolic delivery of CRISPR/Cas9-ribonucleoprotein for efficient gene editing,” ACS Nano 11(3), 2452–2458 (2017).
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H. Nakatsuji, K. Kawabata Galbraith, J. Kurisu, H. Imahori, T. Murakami, and M. Kengaku, “Surface chemistry for cytosolic gene delivery and photothermal transgene expression by gold nanorods,” Sci. Rep. 7(1), 4694 (2017).
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O. Bibikova, P. Singh, A. Popov, G. Akchurin, A. Skaptsov, I. Skovorodkin, V. Khanadeev, D. Mikhalevich, M. Kinnunen, G. Akchurin, V. Bogatyrev, N. Khlebtsov, S. J. Vainio, I. Meglinski, and V. Tuchin, “Shape-dependent interaction of gold nanoparticles with cultured cells at laser exposure,” Laser Phys. Lett. 14(5), 055901 (2017).
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C. Yao, F. Rudnitzki, G. Hüttmann, Z. Zhang, and R. Rahmanzadeh, “Important factors for cell-membrane permeabilization by gold nanoparticles activated by nanosecond-laser irradiation,” Int. J. Nanomedicine 12(12), 5659–5672 (2017).
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J. Hühn, C. Carrillo-Carrion, M. G. Soliman, C. Pfeiffer, D. Valdeperez, A. Masood, I. Chakraborty, L. Zhu, M. Gallego, Z. Yue, M. Carril, N. Feliu, A. Escudero, A. M. Alkilany, B. Pelaz, P. del Pino, and W. J. Parak, “Selected standard protocols for the synthesis, phase transfer, and characterization of inorganic colloidal nanoparticles,” Chem. Mater. 29(1), 399–461 (2017).
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A. O. Rybin, “Green synthesis of gold nanoparticles using silymarin, their effect on animal cell culture in vitro and in vivo,” Agrarian Scientific Journal (11), 37–40 (2017). (in Russian)

H. Qiu, Y. Min, Z. Rodgers, L. Zhang, and A. Z. Wang, “Nanomedicine approaches to improve cancer immunotherapy,” Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 9(5), e1456 (2017).
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A. M. Grimaldi, M. Incoronato, M. Salvatore, and A. Soricelli, “Nanoparticle-based strategies for cancer immunotherapy and immunodiagnostics,” Nanomedicine (Lond.) 12(19), 2349–2365 (2017).
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X. Hu, T. Wu, Y. Bao, and Z. Zhang, “Nanotechnology based therapeutic modality to boost anti-tumor immunity and collapse tumor defense,” J. Control. Release 256, 26–45 (2017).
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L. Luo, R. Shu, and A. Wu, “Nanomaterial-based cancer immunotherapy,” J. Mater. Chem. B Mater. Biol. Med. 5(28), 5517–5531 (2017).
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R. Meir, K. Shamalov, T. Sadan, M. Motiei, G. Yaari, C. J. Cohen, and R. Popovtzer, “Fast image-guided stratification using anti-programmed death ligand 1 gold nanoparticles for cancer immunotherapy,” ACS Nano 11(11), 11127–11134 (2017).
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F. Sousa, P. Castro, P. Fonte, P. J. Kennedy, M. T. Neves-Petersen, and B. Sarmento, “Nanoparticles for the delivery of therapeutic antibodies: Dogma or promising strategy?” Expert Opin. Drug Deliv. 14(10), 1163–1176 (2017).
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E. Spyratou, M. Makropoulou, E. P. Efstathopoulos, A. G. Georgakilas, and L. Sihver, “Recent advances in cancer therapy based on dual mode gold nanoparticles,” Cancers (Basel) 9(12), 173 (2017).
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R. Calderon-Gonzalez, H. Terán-Navarro, I. García, M. Marradi, D. Salcines-Cuevas, S. Yañez-Diaz, A. Solis-Angulo, E. Frande-Cabanes, M. C. Fariñas, A. Garcia-Castaño, J. Gomez-Roman, S. Penades, F. Rivera, J. Freire, and C. Álvarez-Domínguez, “Gold glyconanoparticles coupled to listeriolysin O 91-99 peptide serve as adjuvant therapy against melanoma,” Nanoscale 9(30), 10721–10732 (2017).
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S. Kang, S. Ahn, J. Lee, J. Y. Kim, M. Choi, V. Gujrati, H. Kim, J. Kim, E.-C. Shin, and S. Jon, “Effects of gold nanoparticle-based vaccine size on lymph node delivery and cytotoxic T-lymphocyte responses,” J. Control. Release 256, 56–67 (2017).
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C. Wu, H. Chen, X. Wu, X. Cong, L. Wang, Y. Wang, Y. Yang, W. Li, and T. Sun, “The influence of tumor-induced immune dysfunction on the immune cell distribution of gold nanoparticles in vivo,” Biomater. Sci. 5(8), 1531–1536 (2017).
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K. B. Vang, I. Safina, E. Darrigues, D. Nedosekin, Z. A. Nima, W. Majeed, F. Watanabe, G. Kannarpady, R. A. Kore, D. Casciano, V. P. Zharov, R. J. Griffin, R. P. M. Dings, and A. S. Biris, “Modifying dendritic cell activation with plasmonic nano vectors,” Sci. Rep. 7(1), 5513 (2017).
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R. Liang, J. Xie, J. Li, K. Wang, L. Liu, Y. Gao, M. Hussain, G. Shen, J. Zhu, and J. Tao, “Liposomes-coated gold nanocages with antigens and adjuvants targeted delivery to dendritic cells for enhancing antitumor immune response,” Biomaterials 149, 41–50 (2017).
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X. Zang, X. Zhao, H. Hu, M. Qiao, Y. Deng, and D. Chen, “Nanoparticles for tumor immunotherapy,” Eur. J. Pharm. Biopharm. 115, 243–256 (2017).
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S. Ahmad, A. A. Zamry, H.-T. T. Tan, K. K. Wong, J. Lim, and R. Mohamud, “Targeting dendritic cells through gold nanoparticles: A review on the cellular uptake and subsequent immunological properties,” Mol. Immunol. 91, 123–133 (2017).
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S. Fogli, C. Montis, S. Paccosi, A. Silvano, E. Michelucci, D. Berti, A. Bosi, A. Parenti, and P. Romagnoli, “Inorganic nanoparticles as potential regulators of immune response in dendritic cells,” Nanomedicine (Lond.) 12(14), 1647–1660 (2017).
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D. Chu, X. Dong, Q. Zhao, J. Gu, and Z. Wang, “Photosensitization priming of tumor microenvironments improves delivery of nanotherapeutics via neutrophil infiltration,” Adv. Mater. 29(27), 1701021 (2017).
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B. K. Poudel, B. Gupta, T. Ramasamy, R. K. Thapa, S. Pathak, K. T. Oh, J. H. Jeong, H. G. Choi, C. S. Yong, and J. O. Kim, “PEGylated thermosensitive lipid-coated hollow gold nanoshells for effective combinational chemo-photothermal therapy of pancreatic cancer,” Colloids Surf. B Biointerfaces 160, 73–83 (2017).
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H. Kim, V. P. Nguyen, P. Manivasagan, M. J. Jung, S. W. Kim, J. Oh, and H. W. Kang, “Doxorubicin-fucoidan-gold nanoparticles composite for dual-chemo-photothermal treatment on eye tumors,” Oncotarget 8(69), 113719 (2017).
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R. Mendes, P. Pedrosa, J. C. Lima, A. R. Fernandes, and P. V. Baptista, “Photothermal enhancement of chemotherapy in breast cancer by visible irradiation of Gold Nanoparticles,” Sci. Rep. 7(1), 10872 (2017).
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M. Zhang, H. S. Kim, T. Jin, J. Woo, Y. J. Piao, and W. K. Moon, “Near-infrared photothermal therapy using anti-EGFR-gold nanorod conjugates for triple negative breast cancer,” Oncotarget 8(49), 86566–86575 (2017).
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M. I. Setyawati, C. Y. Tay, B. H. Bay, and D. T. Leong, “Gold nanoparticles induced endothelial leakiness depends on particle size and endothelial cell origin,” ACS Nano 11(5), 5020–5030 (2017).
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C. Y. Tay, M. I. Setyawati, and D. T. Leong, “Nanoparticle density: a critical biophysical regulator of endothelial permeability,” ACS Nano 11(3), 2764–2772 (2017).
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Y. Yi, H. Wang, X. Wang, Q. Liu, M. Ye, and W. Tan, “A smart, photocontrollable drug release nanosystem for multifunctional synergistic cancer therapy,” ACS Appl. Mater. Interfaces 9(7), 5847–5854 (2017).
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K.-Q. Lin, J. Yi, J.-H. Zhong, S. Hu, B.-J. Liu, J.-Y. Liu, C. Zong, Z.-C. Lei, X. Wang, J. Aizpurua, R. Esteban, and B. Ren, “Plasmonic photoluminescence for recovering native chemical information from surface-enhanced Raman scattering,” Nat. Commun. 8(1), 14891 (2017).
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2016 (25)

M. Zhang, T. Yilmaz, A. O. Boztas, O. Karakuzu, W. Y. Bang, Y. Yegin, Z. Luo, M. Lenox, L. Cisneros-Zevallos, and M. Akbulut, “A multifunctional nanoparticulate theranostic system with simultaneous chemotherapeutic, photothermal therapeutic, and MRI contrast capabilities,” RSC Advances 6(33), 27798–27806 (2016).
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Z. Wang, S. Li, M. Zhang, Y. Ma, Y. Liu, W. Gao, J. Zhang, and Y. Gu, “Laser-triggered small interfering RNA releasing gold nanoshells against heat shock protein for sensitized photothermal therapy,” Adv. Sci. (Weinh.) 4(2), 1600327 (2016).
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S. Baek, R. K. Singh, T.-H. Kim, J.-W. Seo, U. S. Shin, W. Chrzanowski, and H.-W. Kim, “Triple hit with drug carriers: pH- and temperature-responsive theranostics for multimodal chemo- and photothermal-therapy and diagnostic applications,” ACS Appl. Mater. Interfaces 8(14), 8967–8979 (2016).
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T. H. Tran, R. K. Thapa, H. T. Nguyen, T. T. Pham, T. Ramasamy, D. S. Kim, C. S. Yong, J. O. Kim, and H.-G. Choi, “Combined phototherapy in anti-cancer treatment: therapeutics design and perspectives,” J. Pharm. Investig. 46(6), 505–517 (2016).
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S. Saha, X. Xiong, P. K. Chakraborty, K. Shameer, R. R. Arvizo, R. A. Kudgus, S. K. D. Dwivedi, M. N. Hossen, E. M. Gillies, J. D. Robertson, J. T. Dudley, R. A. Urrutia, R. G. Postier, R. Bhattacharya, and P. Mukherjee, “Gold nanoparticle reprograms pancreatic tumor microenvironment and inhibits tumor growth,” ACS Nano 10(12), 10636–10651 (2016).
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Q. Zhou, Y. Zhang, J. Du, Y. Li, Y. Zhou, Q. Fu, J. Zhang, X. Wang, and L. Zhan, “Different-sized gold nanoparticle activator/antigen increases dendritic cells accumulation in liver-draining lymph nodes and Cd8+ T cell responses,” ACS Nano 10(2), 2678–2692 (2016).
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X. Ma, H. Hui, Y. Jin, D. Dong, X. Liang, X. Yang, K. Tan, Z. Dai, Z. Cheng, and J. Tian, “Enhanced immunotherapy of SM5-1 in hepatocellular carcinoma by conjugating with gold nanoparticles and its in vivo bioluminescence tomographic evaluation,” Biomaterials 87, 46–56 (2016).
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J. N. Payne, H. K. Waghwani, M. G. Connor, W. Hamilton, S. Tockstein, H. Moolani, F. Chavda, V. Badwaik, M. B. Lawrenz, and R. Dakshinamurthy, “Novel synthesis of kanamycin conjugated gold nanoparticles with potent antibacterial activity,” Front. Microbiol. 7, 607 (2016).
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M. Khoobchandani, K. Katti, A. Maxwell, W. P. Fay, and K. V. Katti, “Laminin receptor-avid nanotherapeutic EGCg-AuNPs as a potential alternative therapeutic approach to prevent restenosis,” Int. J. Mol. Sci. 17(3), 316 (2016).
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Z. Lyu, F. Zhou, Q. Liu, H. Xue, Q. Yu, and H. Chen, “A universal platform for macromolecular deliveryinto cells using gold nanoparticle layers via the photoporation effect,” Adv. Funct. Mater. 26(32), 5787–5795 (2016).
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H. Ledford, “CRISPR: gene editing is just the beginning,” Nature 531(7593), 156–159 (2016).
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N. Rattanata, S. Klaynongsruang, C. Leelayuwat, T. Limpaiboon, A. Lulitanond, P. Boonsiri, S. Chio-Srichan, S. Soontaranon, S. Rugmai, and J. Daduang, “Gallic acid conjugated with gold nanoparticles: antibacterial activity and mechanism of action on foodborne pathogens,” Int. J. Nanomedicine 11(11), 3347–3356 (2016).
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S. M. Pradeepa, S. M. Vidya, S. Mutalik, K. Udaya Bhat, P. Huilgol, and K. Avadhani, “Preparation of gold nanoparticles by novel bacterial exopolysaccharide for antibiotic delivery,” Life Sci. 153, 171–179 (2016).
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A. Ahmed, A. K. Khan, A. Anwar, S. A. Ali, and M. R. Shah, “Biofilm inhibitory effect of chlorhexidine conjugated gold nanoparticles against Klebsiella pneumoniae,” Microb. Pathog. 98, 50–56 (2016).
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S. Wilhelm, A. J. Tavares, Q. Dai, S. Ohta, J. Audet, H. F. Dvorak, and W. C. Chan, “Analysis of nanoparticle delivery to tumours,” Nat. Rev. Mater. 1(5), 16014 (2016).
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L.-H. Peng, Y.-F. Huang, C.-Z. Zhang, J. Niu, Y. Chen, Y. Chu, Z.-H. Jiang, J.-Q. Gao, and Z.-W. Mao, “Integration of antimicrobial peptides with gold nanoparticles as unique non-viral vectors for gene delivery to mesenchymal stem cells with antibacterial activity,” Biomaterials 103, 137–149 (2016).
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S. Kalita, R. Kandimalla, K. K. Sharma, A. C. Kataki, M. Deka, and J. Kotoky, “Amoxicillin functionalized gold nanoparticles reverts MRSA resistance,” Mater. Sci. Eng. C 61, 720–727 (2016).
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H. R. Ali, M. R. Ali, Y. Wu, S. A. Selim, H. F. Abdelaal, E. A. Nasr, and M. A. El-Sayed, “Gold nanorods as drug delivery vehicles for rifampicin greatly improve the efficacy of combating Mycobacterium tuberculosis with good biocompatibility with the host cells,” Bioconjug. Chem. 27(10), 2486–2492 (2016).
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L. Du, S. Suo, H. Zhang, H. Jia, K. J. Liu, X. J. Zhang, and Y. Liu, “The alternative strategy for designing covalent drugs through kinetic effects of pi-stacking on the self-assembled nanoparticles: a model study with antibiotics,” Nanotechnology 27(44), 445101 (2016).
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R. A. Morshed, M. E. Muroski, Q. Dai, M. L. Wegscheid, B. Auffinger, D. Yu, Y. Han, L. Zhang, M. Wu, Y. Cheng, and M. S. Lesniak, “Cell-penetrating peptide-modified gold nanoparticles for the delivery of doxorubicin to brain metastatic breast cancer,” Mol. Pharm. 13(6), 1843–1854 (2016).
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C. S. Kumar, A. Mahesh, M. G. Antoniraj, S. Vaidevi, and K. Ruckmani, “Ultrafast synthesis of stabilized gold nanoparticles using aqueous fruit extract of Limonia acidissima L. and conjugated epirubicin: targeted drug delivery for treatment of breast cancer,” RSC Advances 6(32), 26874–26882 (2016).
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N. Rizk, N. Christoforou, and S. Lee, “Optimization of anti-cancer drugs and a targeting molecule on multifunctional gold nanoparticles,” Nanotechnology 27(18), 185704 (2016).
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A. Pradhan, M. Bepari, P. Maity, S. S. Roy, S. Roy, and S. M. Choudhury, “Gold nanoparticles from indole-3-carbinol exhibit cytotoxic, genotoxic and antineoplastic effects through the induction of apoptosis,” RSC Advances 6(61), 56435–56449 (2016).
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C. Yao, L. Zhang, J. Wang, Y. He, J. Xin, S. Wang, H. Xu, and Z. Zhang, “Gold nanoparticle mediated phototherapy for cancer,” J. Nanomater. 2016, 1 (2016).
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L. A. Dykman and N. G. Khlebtsov, “Multifunctional gold-based nanocomposites for theranostics,” Biomaterials 108, 13–34 (2016).
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2015 (18)

X. Yang, M. Yang, B. Pang, M. Vara, and Y. Xia, “Gold nanomaterials at work in biomedicine,” Chem. Rev. 115(19), 10410–10488 (2015).
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S. Labala, P. K. Mandapalli, A. Kurumaddali, and V. V. K. Venuganti, “Layer-by-layer polymer coated gold nanoparticles for topical delivery of imatinib mesylate to treat melanoma,” Mol. Pharm. 12(3), 878–888 (2015).
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M. Shilo, P. Berenstein, T. Dreifuss, Y. Nash, G. Goldsmith, G. Kazimirsky, M. Motiei, D. Frenkel, C. Brodie, and R. Popovtzer, “Insulin-coated gold nanoparticles as a new concept for personalized and adjustable glucose regulation,” Nanoscale 7(48), 20489–20496 (2015).
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N. Gao, H. Sun, K. Dong, J. Ren, and X. Qu, “Gold-nanoparticle-based multifunctional amyloid-β inhibitor against Alzheimer’s disease,” Chemistry 21(2), 829–835 (2015).
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A. A. H. Abdellatif, S. A. E. Rasoul, and S. Osman, “Gold nanoparticles decorated with octreotide for somatostatin receptors targeting,” J. Pharm. Sci. Res. 7(1), 14–20 (2015).

M. Schomaker, D. Killian, S. Willenbrock, D. Heinemann, S. Kalies, A. Ngezahayo, I. Nolte, T. Ripken, C. Junghanß, H. Meyer, H. Murua Escobar, and A. Heisterkamp, “Biophysical effects in off-resonant gold nanoparticle mediated (GNOME) laser transfection of cell lines, primary- and stem cells using fs laser pulses,” J. Biophotonics 8(8), 646–658 (2015).
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H.-Z. Lai, W.-Y. Chen, C.-Y. Wu, and Y.-C. Chen, “Potent antibacterial nanoparticles for pathogenic bacteria,” ACS Appl. Mater. Interfaces 7(3), 2046–2054 (2015).
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S. Biswas, S. H. Medina, and J. J. Barchi, “Synthesis and cell-selective antitumor properties of amino acid conjugated tumor-associated carbohydrate antigen-coated gold nanoparticles,” Carbohydr. Res. 405, 93–101 (2015).
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J. P. M. Almeida, A. Y. Lin, E. R. Figueroa, A. E. Foster, and R. A. Drezek, “In vivo gold nanoparticle delivery of peptide vaccine induces anti-tumor immune response in prophylactic and therapeutic tumor models,” Small 11(12), 1453–1459 (2015).
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K. de Oliveira Gonçalves, M. N. da Silva, L. B. Sicchieri, F. R. de Oliveira Silva, R. A. de Matos, and L. C. Courrol, “Aminolevulinic acid with gold nanoparticles: a novel theranostic agent for atherosclerosis,” Analyst (Lond.) 140(6), 1974–1980 (2015).
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H. Chen, F. Liu, Z. Lei, L. Ma, and Z. Wang, “Fe2O3@Au core@shell nanoparticle–graphene nanocomposites as theranostic agents for bioimaging and chemo-photothermal synergistic therapy,” RSC Advances 5(103), 84980–84987 (2015).
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W.-H. Chen, C.-X. Yang, W.-X. Qiu, G.-F. Luo, H.-Z. Jia, Q. Lei, X.-Y. Wang, G. Liu, R.-X. Zhuo, and X.-Z. Zhang, “Multifunctional theranostic nanoplatform for cancer combined therapy based on gold nanorods,” Adv. Healthc. Mater. 4(15), 2247–2259 (2015).
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F. Hu, Y. Zhang, G. Chen, C. Li, and Q. Wang, “Double-walled Au nanocage/SiO2 nanorattles: integrating SERS imaging, drug delivery and photothermal therapy,” Small 11(8), 985–993 (2015).
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Y. Hao, B. Zhang, C. Zheng, R. Ji, X. Ren, F. Guo, S. Sun, J. Shi, H. Zhang, Z. Zhang, L. Wang, and Y. Zhang, “The tumor-targeting core-shell structured DTX-loaded PLGA@Au nanoparticles for chemo-photothermal therapy and X-ray imaging,” J. Control. Release 220(Pt A), 545–555 (2015).
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Y. Yuan, Y. Zhang, B. Liu, H. Wu, Y. Kang, M. Li, X. Zeng, N. He, and G. Zhang, “The effects of multifunctional MiR-122-loaded graphene-gold composites on drug-resistant liver cancer,” J. Nanobiotechnology 13(1), 12 (2015).
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M. Hembury, C. Chiappini, S. Bertazzo, T. L. Kalber, G. L. Drisko, O. Ogunlade, S. Walker-Samuel, K. S. Krishna, C. Jumeaux, P. Beard, C. S. Kumar, A. E. Porter, M. F. Lythgoe, C. Boissière, C. Sanchez, and M. M. Stevens, “Gold-silica quantum rattles for multimodal imaging and therapy,” Proc. Natl. Acad. Sci. U.S.A. 112(7), 1959–1964 (2015).
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H. Deng, F. Dai, G. Ma, and X. Zhang, “Theranostic gold nanomicelles made from biocompatible comb-like polymers for thermochemotherapy and multifunctional imaging with rapid clearance,” Adv. Mater. 27(24), 3645–3653 (2015).
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C.-C. Huang and T.-M. Liu, “Controlled Au-polymer nanostructures for multiphoton imaging, prodrug delivery, and chemo-photothermal therapy platforms,” ACS Appl. Mater. Interfaces 7(45), 25259–25269 (2015).
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2014 (26)

X. Li, M. Takashima, E. Yuba, A. Harada, and K. Kono, “PEGylated PAMAM dendrimer-doxorubicin conjugate-hybridized gold nanorod for combined photothermal-chemotherapy,” Biomaterials 35(24), 6576–6584 (2014).
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Z. Zhang, J. Wang, X. Nie, T. Wen, Y. Ji, X. Wu, Y. Zhao, and C. Chen, “Near infrared laser-induced targeted cancer therapy using thermoresponsive polymer encapsulated gold nanorods,” J. Am. Chem. Soc. 136(20), 7317–7326 (2014).
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P. Vijayaraghavan, C. H. Liu, R. Vankayala, C. S. Chiang, and K. C. Hwang, “Designing multi-branched gold nanoechinus for NIR light activated dual modal photodynamic and photothermal therapy in the second biological window,” Adv. Mater. 26(39), 6689–6695 (2014).
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A. Barhoumi, W. Wang, D. Zurakowski, R. S. Langer, and D. S. Kohane, “Photothermally targeted thermosensitive polymer-masked nanoparticles,” Nano Lett. 14(7), 3697–3701 (2014).
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A. Topete, M. Alatorre-Meda, P. Iglesias, E. M. Villar-Alvarez, S. Barbosa, J. A. Costoya, P. Taboada, and V. Mosquera, “Fluorescent drug-loaded, polymeric-based, branched gold nanoshells for localized multimodal therapy and imaging of tumoral cells,” ACS Nano 8(3), 2725–2738 (2014).
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W. Zhang, Y. Wang, X. Sun, W. Wang, and L. Chen, “Mesoporous titania based yolk-shell nanoparticles as multifunctional theranostic platforms for SERS imaging and chemo-photothermal treatment,” Nanoscale 6(23), 14514–14522 (2014).
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L. A. Dykman and N. G. Khlebtsov, “Uptake of engineered gold nanoparticles into mammalian cells,” Chem. Rev. 114(2), 1258–1288 (2014).
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I. Melero, G. Gaudernack, W. Gerritsen, C. Huber, G. Parmiani, S. Scholl, N. Thatcher, J. Wagstaff, C. Zielinski, I. Faulkner, and H. Mellstedt, “Therapeutic vaccines for cancer: an overview of clinical trials,” Nat. Rev. Clin. Oncol. 11(9), 509–524 (2014).
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J. P. M. Almeida, A. Y. Lin, R. J. Langsner, P. Eckels, A. E. Foster, and R. A. Drezek, “In vivo immune cell distribution of gold nanoparticles in naïve and tumor bearing mice,” Small 10(4), 812–819 (2014).
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J. P. M. Almeida, E. R. Figueroa, and R. A. Drezek, “Gold nanoparticle mediated cancer immunotherapy,” Nanomedicine (Lond.) 10(3), 503–514 (2014).
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S. Ahn, I. H. Lee, S. Kang, D. Kim, M. Choi, P. E. Saw, E. C. Shin, and S. Jon, “Gold nanoparticles displaying tumor-associated self-antigens as a potential vaccine for cancer immunotherapy,” Adv. Healthc. Mater. 3(8), 1194–1199 (2014).
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S. Tomić, J. Ðokić, S. Vasilijić, N. Ogrinc, R. Rudolf, P. Pelicon, D. Vučević, P. Milosavljević, S. Janković, I. Anžel, J. Rajković, M. S. Rupnik, B. Friedrich, and M. Colić, “Size-dependent effects of gold nanoparticles uptake on maturation and antitumor functions of human dendritic cells in vitro,” PLoS One 9(5), e96584 (2014).
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Y. Tao, E. Ju, Z. Liu, K. Dong, J. Ren, and X. Qu, “Engineered, self-assembled near-infrared photothermal agents for combined tumor immunotherapy and chemo-photothermal therapy,” Biomaterials 35(24), 6646–6656 (2014).
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H. A. Andersson, Y.-S. Kim, B. E. O’Neill, Z.-Z. Shi, and R. E. Serda, “HSP70 promoter-driven activation of gene expression for immunotherapy using gold nanorods and near infrared light,” Vaccines (Basel) 2(2), 216–227 (2014).
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L. Cohn and L. Delamarre, “Dendritic cell-targeted vaccines,” Front. Immunol. 5, 255 (2014).
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M. Demurtas and C. C. Perry, “Facile one-pot synthesis of amoxicillin-coated gold nanoparticles and their antimicrobial activity,” Gold Bull. 47(1–2), 103–107 (2014).
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Y. E. Hur, S. Kim, J.-H. Kim, S.-H. Cha, M.-J. Choi, S. Cho, and Y. Park, “One-step functionalization of gold and silver nanoparticles by ampicillin,” Mater. Lett. 129, 185–190 (2014).
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R. Xiong, K. Raemdonck, K. Peynshaert, I. Lentacker, I. De Cock, J. Demeester, S. C. De Smedt, A. G. Skirtach, and K. Braeckmans, “Comparison of gold nanoparticle mediated photoporation: vapor nanobubbles outperform direct heating for delivering macromolecules in live cells,” ACS Nano 8(6), 6288–6296 (2014).
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S. N. Barnaby, A. Lee, and C. A. Mirkin, “Probing the inherent stability of siRNA immobilized on nanoparticle constructs,” Proc. Natl. Acad. Sci. U.S.A. 111(27), 9739–9744 (2014).
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N. Kabir, H. Ali, M. Ateeq, M. F. Bertino, M. R. Shah, and L. Franzel, “Silymarin coated gold nanoparticles ameliorates CCl4-induced hepatic injury and cirrhosis through down regulation of Hepatic stellate cells and attenuation of Kupffer cells,” RSC Advances 4(18), 9012–9020 (2014).
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H. Lee, M.-Y. Lee, S. H. Bhang, B.-S. Kim, Y. S. Kim, J. H. Ju, K. S. Kim, and S. K. Hahn, “Hyaluronate-gold nanoparticle/tocilizumab complex for the treatment of rheumatoid arthritis,” ACS Nano 8(5), 4790–4798 (2014).
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H.-J. Cho, J. Oh, M.-K. Choo, J.-I. Ha, Y. Park, and H.-J. Maeng, “Chondroitin sulfate-capped gold nanoparticles for the oral delivery of insulin,” Int. J. Biol. Macromol. 63, 15–20 (2014).
[Crossref] [PubMed]

F. Chiodo, M. Marradi, J. Calvo, E. Yuste, and S. Penadés, “Glycosystems in nanotechnology: Gold glyconanoparticles as carrier for anti-HIV prodrugs,” Beilstein J. Org. Chem. 10, 1339–1346 (2014).
[Crossref] [PubMed]

H.-W. Kao, Y.-Y. Lin, C.-C. Chen, K.-H. Chi, D.-C. Tien, C.-C. Hsia, W.-J. Lin, F.-D. Chen, M.-H. Lin, and H.-E. Wang, “Biological characterization of cetuximab-conjugated gold nanoparticles in a tumor animal model,” Nanotechnology 25(29), 295102 (2014).
[Crossref] [PubMed]

C.-C. Chen, D.-S. Hsieh, K.-J. Huang, Y.-L. Chan, P.-D. Hong, M.-K. Yeh, and C.-J. Wu, “Improving anticancer efficacy of (-)-epigallocatechin-3-gallate gold nanoparticles in murine B16F10 melanoma cells,” Drug Des. Devel. Ther. 8(8), 459–474 (2014).
[PubMed]

R. Cao-Milán and L. M. Liz-Marzán, “Gold nanoparticle conjugates: recent advances toward clinical applications,” Expert Opin. Drug Deliv. 11(5), 741–752 (2014).
[Crossref] [PubMed]

2013 (19)

L. Vigderman and E. R. Zubarev, “Therapeutic platforms based on gold nanoparticles and their covalent conjugates with drug molecules,” Adv. Drug Deliv. Rev. 65(5), 663–676 (2013).
[Crossref] [PubMed]

Y. Zhao and X. Jiang, “Multiple strategies to activate gold nanoparticles as antibiotics,” Nanoscale 5(18), 8340–8350 (2013).
[Crossref] [PubMed]

S. Pandey, A. Mewada, M. Thakur, R. Shah, G. Oza, and M. Sharon, “Biogenic gold nanoparticles as fotillas to fire berberine hydrochloride using folic acid as molecular road map,” Mater. Sci. Eng. C 33(7), 3716–3722 (2013).
[Crossref] [PubMed]

S. C. Coelho, S. Rocha, P. Juzenas, P. Sampaio, G. M. Almeida, F. S. Silva, M. C. Pereira, and M. A. Coelho, “Gold nanoparticle delivery-enhanced proteasome inhibitor effect in adenocarcinoma cells,” Expert Opin. Drug Deliv. 10(10), 1345–1352 (2013).
[Crossref] [PubMed]

A. Gomes, P. Datta, J. Sengupta, A. Biswas, and A. Gomes, “Evaluation of anti-arthritic property of methotrexate conjugated gold nanoparticle on experimental animal models,” J. Nanopharm. Drug Deliv. 1(2), 206–211 (2013).
[Crossref]

K. E. Sapsford, W. R. Algar, L. Berti, K. B. Gemmill, B. J. Casey, E. Oh, M. H. Stewart, and I. L. Medintz, “Functionalizing nanoparticles with biological molecules: developing chemistries that facilitate nanotechnology,” Chem. Rev. 113(3), 1904–2074 (2013).
[Crossref] [PubMed]

S. Das, P. Roy, S. Mondal, T. Bera, and A. Mukherjee, “One pot synthesis of gold nanoparticles and application in chemotherapy of wild and resistant type visceral leishmaniasis,” Colloids Surf. B Biointerfaces 107, 27–34 (2013).
[Crossref] [PubMed]

J. Shao, R. J. Griffin, E. I. Galanzha, J. W. Kim, N. Koonce, J. Webber, T. Mustafa, A. S. Biris, D. A. Nedosekin, and V. P. Zharov, “Photothermal nanodrugs: potential of TNF-gold nanospheres for cancer theranostics,” Sci. Rep. 3(1), 1293 (2013).
[Crossref] [PubMed]

J. Nam, W.-G. La, S. Hwang, Y. S. Ha, N. Park, N. Won, S. Jung, S. H. Bhang, Y.-J. Ma, Y.-M. Cho, M. Jin, J. Han, J.-Y. Shin, E. K. Wang, S. G. Kim, S.-H. Cho, J. Yoo, B.-S. Kim, and S. Kim, “pH-responsive assembly of gold nanoparticles and “spatiotemporally concerted” drug release for synergistic cancer therapy,” ACS Nano 7(4), 3388–3402 (2013).
[Crossref] [PubMed]

A. L. Parry, N. A. Clemson, J. Ellis, S. S. R. Bernhard, B. G. Davis, and N. R. Cameron, “‘Multicopy multivalent’ glycopolymer-stabilized gold nanoparticles as potential synthetic cancer vaccines,” J. Am. Chem. Soc. 135(25), 9362–9365 (2013).
[Crossref] [PubMed]

Y. M. Park, S. J. Lee, Y. S. Kim, M. H. Lee, G. S. Cha, I. D. Jung, T. H. Kang, and H. D. Han, “Nanoparticle-based vaccine delivery for cancer immunotherapy,” Immune Netw. 13(5), 177–183 (2013).
[Crossref] [PubMed]

A. Y. Lin, J. P. Almeida, A. Bear, N. Liu, L. Luo, A. E. Foster, and R. A. Drezek, “Gold nanoparticle delivery of modified CpG stimulates macrophages and inhibits tumor growth for enhanced immunotherapy,” PLoS One 8(5), e63550 (2013).
[Crossref] [PubMed]

Y. S. Tsai, Y. H. Chen, P. C. Cheng, H. T. Tsai, A. L. Shiau, T. S. Tzai, and C. L. Wu, “TGF-β1 conjugated to gold nanoparticles results in protein conformational changes and attenuates the biological function,” Small 9(12), 2119–2128 (2013).
[Crossref] [PubMed]

A. Y. Lin, J. Lunsford, A. S. Bear, J. K. Young, P. Eckels, L. Luo, A. E. Foster, and R. A. Drezek, “High-density sub-100-nm peptide-gold nanoparticle complexes improve vaccine presentation by dendritic cells in vitro,” Nanoscale Res. Lett. 8(1), 72 (2013).
[Crossref] [PubMed]

M. I. Setyawati, C. Y. Tay, S. L. Chia, S. L. Goh, W. Fang, M. J. Neo, H. C. Chong, S. M. Tan, S. C. Loo, K. W. Ng, J. P. Xie, C. N. Ong, N. S. Tan, and D. T. Leong, “Titanium dioxide nanomaterials cause endothelial cell leakiness by disrupting the homophilic interaction of VE-cadherin,” Nat. Commun. 4(1), 1673 (2013).
[Crossref] [PubMed]

Z. Jiang, B. Dong, B. Chen, J. Wang, L. Xu, S. Zhang, and H. Song, “Multifunctional Au@mSiO2/rhodamine B isothiocyanate nanocomposites: cell imaging, photocontrolled drug release, and photothermal therapy for cancer cells,” Small 9(4), 604–612 (2013).
[Crossref] [PubMed]

S. Marrache, J. H. Choi, S. Tundup, D. Zaver, D. A. Harn, and S. Dhar, “Immune stimulating photoactive hybrid nanoparticles for metastatic breast cancer,” Integr. Biol. 5(1), 215–223 (2013).
[Crossref] [PubMed]

H. Chen, X. Zhang, S. Dai, Y. Ma, S. Cui, S. Achilefu, and Y. Gu, “Multifunctional gold nanostar conjugates for tumor imaging and combined photothermal and chemo-therapy,” Theranostics 3(9), 633–649 (2013).
[Crossref] [PubMed]

R. Chen, X. Zheng, H. Qian, X. Wang, J. Wang, and X. Jiang, “Combined near-IR photothermal therapy and chemotherapy using gold-nanorod/chitosan hybrid nanospheres to enhance the antitumor effect,” Biomater. Sci. 1(3), 285–293 (2013).
[Crossref]

2012 (20)

Z. Zhang, L. Wang, J. Wang, X. Jiang, X. Li, Z. Hu, Y. Ji, X. Wu, and C. Chen, “Mesoporous silica-coated gold nanorods as a light-mediated multifunctional theranostic platform for cancer treatment,” Adv. Mater. 24(11), 1418–1423 (2012).
[Crossref] [PubMed]

Y. Wang, L. Chen, and P. Liu, “Biocompatible triplex Ag@SiO2@mTiO2 core-shell nanoparticles for simultaneous fluorescence-SERS bimodal imaging and drug delivery,” Chemistry 18(19), 5935–5943 (2012).
[Crossref] [PubMed]

D. N. Heo, D. H. Yang, H.-J. Moon, J. B. Lee, M. S. Bae, S. C. Lee, W. J. Lee, I.-C. Sun, and I. K. Kwon, “Gold nanoparticles surface-functionalized with paclitaxel drug and biotin receptor as theranostic agents for cancer therapy,” Biomaterials 33(3), 856–866 (2012).
[Crossref] [PubMed]

M. Ma, H. Chen, Y. Chen, X. Wang, F. Chen, X. Cui, and J. Shi, “Au capped magnetic core/mesoporous silica shell nanoparticles for combined photothermo-/chemo-therapy and multimodal imaging,” Biomaterials 33(3), 989–998 (2012).
[Crossref] [PubMed]

R. P. Brinãs, A. Sundgren, P. Sahoo, S. Morey, K. Rittenhouse-Olson, G. E. Wilding, W. Deng, and J. J. Barchi, “Design and synthesis of multifunctional gold nanoparticles bearing tumor-associated glycopeptide antigens as potential cancer vaccines,” Bioconjug. Chem. 23(8), 1513–1523 (2012).
[Crossref] [PubMed]

M. Wei, N. Chen, J. Li, M. Yin, L. Liang, Y. He, H. Song, C. Fan, and Q. Huang, “Polyvalent immunostimulatory nanoagents with self-assembled CpG oligonucleotide-conjugated gold nanoparticles,” Angew. Chem. Int. Ed. Engl. 51(5), 1202–1206 (2012).
[Crossref] [PubMed]

I. H. Lee, H. K. Kwon, S. An, D. Kim, S. Kim, M. K. Yu, J. H. Lee, T. S. Lee, S. H. Im, and S. Jon, “Imageable antigen-presenting gold nanoparticle vaccines for effective cancer immunotherapy in vivo,” Angew. Chem. Int. Ed. Engl. 51(35), 8800–8805 (2012).
[Crossref] [PubMed]

G. Bisker, D. Yeheskely-Hayon, L. Minai, and D. Yelin, “Controlled release of Rituximab from gold nanoparticles for phototherapy of malignant cells,” J. Control. Release 162(2), 303–309 (2012).
[Crossref] [PubMed]

J. You, R. Zhang, G. Zhang, M. Zhong, Y. Liu, C. S. Van Pelt, D. Liang, W. Wei, A. K. Sood, and C. Li, “Photothermal-chemotherapy with doxorubicin-loaded hollow gold nanospheres: A platform for near-infrared light-trigged drug release,” J. Control. Release 158(2), 319–328 (2012).
[Crossref] [PubMed]

E. C. Dreaden, S. C. Mwakwari, L. A. Austin, M. J. Kieffer, A. K. Oyelere, and M. A. El-Sayed, “Small molecule-gold nanorod conjugates selectively target and induce macrophage cytotoxicity towards breast cancer cells,” Small 8(18), 2819–2822 (2012).
[Crossref] [PubMed]

Y.-J. Huang, A.-L. Shiau, S.-Y. Chen, Y.-L. Chen, C.-R. Wang, C.-Y. Tsai, M.-Y. Chang, Y.-T. Li, C.-H. Leu, and C.-L. Wu, “Multivalent structure of galectin-1-nanogold complex serves as potential therapeutics for rheumatoid arthritis by enhancing receptor clustering,” Eur. Cell. Mater. 23, 170–181 (2012).
[Crossref] [PubMed]

O. Ehsan, M. I. Qadir, S. A. Malik, W. S. Abbasi, and B. Ahmad, “Efficacy of nanogold-insulin as a hypoglycemic agent,” J. Chem. Soc. Pak. 34(2), 365–370 (2012).

L. Rastogi, A. J. Kora, and A. Arunachalam, “Highly stable, protein capped gold nanoparticles as effective drug delivery vehicles for amino-glycosidic antibiotics,” Mater. Sci. Eng. C 32(6), 1571–1577 (2012).
[Crossref] [PubMed]

S. Manju and K. Sreenivasan, “Gold nanoparticles generated and stabilized by water soluble curcumin-polymer conjugate: blood compatibility evaluation and targeted drug delivery onto cancer cells,” J. Colloid Interface Sci. 368(1), 144–151 (2012).
[Crossref] [PubMed]

C. Tomuleasa, O. Soritau, A. Orza, M. Dudea, B. Petrushev, O. Mosteanu, S. Susman, A. Florea, E. Pall, M. Aldea, G. Kacso, V. Cristea, I. Berindan-Neagoe, and A. Irimie, “Gold nanoparticles conjugated with cisplatin/doxorubicin/capecitabine lower the chemoresistance of hepatocellular carcinoma-derived cancer cells,” J. Gastrointestin. Liver Dis. 21(2), 187–196 (2012).
[PubMed]

P. Joshi, S. Chakraborti, J. E. Ramirez-Vick, Z. A. Ansari, V. Shanker, P. Chakrabarti, and S. P. Singh, “The anticancer activity of chloroquine-gold nanoparticles against MCF-7 breast cancer cells,” Colloids Surf. B Biointerfaces 95, 195–200 (2012).
[Crossref] [PubMed]

A. Llevot and D. Astruc, “Applications of vectorized gold nanoparticles to the diagnosis and therapy of cancer,” Chem. Soc. Rev. 41(1), 242–257 (2012).
[Crossref] [PubMed]

L. Dykman and N. Khlebtsov, “Gold nanoparticles in biomedical applications: recent advances and perspectives,” Chem. Soc. Rev. 41(6), 2256–2282 (2012).
[Crossref] [PubMed]

E. C. Dreaden, A. M. Alkilany, X. Huang, C. J. Murphy, and M. A. El-Sayed, “The golden age: gold nanoparticles for biomedicine,” Chem. Soc. Rev. 41(7), 2740–2779 (2012).
[Crossref] [PubMed]

A. Kumar, H. Ma, X. Zhang, K. Huang, S. Jin, J. Liu, T. Wei, W. Cao, G. Zou, and X.-J. Liang, “Gold nanoparticles functionalized with therapeutic and targeted peptides for cancer treatment,” Biomaterials 33(4), 1180–1189 (2012).
[Crossref] [PubMed]

2011 (5)

E. C. Dreaden, M. A. Mackey, X. Huang, B. Kang, and M. A. El-Sayed, “Beating cancer in multiple ways using nanogold,” Chem. Soc. Rev. 40(7), 3391–3404 (2011).
[Crossref] [PubMed]

A. François, A. Laroche, N. Pinaud, L. Salmon, J. Ruiz, J. Robert, and D. Astruc, “Encapsulation of docetaxel into PEGylated gold nanoparticles for vectorization to cancer cells,” ChemMedChem 6(11), 2003–2008 (2011).
[Crossref] [PubMed]

F. Wang, Y. C. Wang, S. Dou, M. H. Xiong, T. M. Sun, and J. Wang, “Doxorubicin-tethered responsive gold nanoparticles facilitate intracellular drug delivery for overcoming multidrug resistance in cancer cells,” ACS Nano 5(5), 3679–3692 (2011).
[Crossref] [PubMed]

P. M. Tiwari, K. Vig, V. A. Dennis, and S. R. Singh, “Functionalized gold nanoparticles and their biomedical applications,” Nanomaterials (Basel) 1(1), 31–63 (2011).
[Crossref] [PubMed]

L. J. Cruz, F. Rueda, B. Cordobilla, L. Simón, L. Hosta, F. Albericio, and J. C. Domingo, “Targeting nanosystems to human DCs via Fc receptor as an effective strategy to deliver antigen for immunotherapy,” Mol. Pharm. 8(1), 104–116 (2011).
[Crossref] [PubMed]

2010 (8)

F.-Y. Cheng, C.-H. Su, P.-C. Wu, and C.-S. Yeh, “Multifunctional polymeric nanoparticles for combined chemotherapeutic and near-infrared photothermal cancer therapy in vitro and in vivo,” Chem. Commun. (Camb.) 46(18), 3167–3169 (2010).
[Crossref] [PubMed]

S.-M. Lee, H. Park, and K.-H. Yoo, “Synergistic cancer therapeutic effects of locally delivered drug and heat using multifunctional nanoparticles,” Adv. Mater. 22(36), 4049–4053 (2010).
[Crossref] [PubMed]

X. Huang, X. Peng, Y. Wang, Y. Wang, D. M. Shin, M. A. El-Sayed, and S. Nie, “A reexamination of active and passive tumor targeting by using rod-shaped gold nanocrystals and covalently conjugated peptide ligands,” ACS Nano 4(10), 5887–5896 (2010).
[Crossref] [PubMed]

Y. Zhao, Y. Tian, Y. Cui, W. Liu, W. Ma, and X. Jiang, “Small molecule-capped gold nanoparticles as potent antibacterial agents that target Gram-negative bacteria,” J. Am. Chem. Soc. 132(35), 12349–12356 (2010).
[Crossref] [PubMed]

S. A. Staroverov, O. A. Gasina, A. A. Kladiev, and V. A. Bogatyrev, “The impact of complex prospidin–colloidal gold on tumor cells,” Russian Journal of Biotherapy 9(3), 22–23 (2010).

Z. Xing, Z. Liu, Y. Zu, Y. Fu, C. Zhao, X. Zhao, R. Meng, and S. Tan, “Synthesis of camptothecin-loaded gold nanomaterials,” Appl. Surf. Sci. 256(12), 3917–3920 (2010).
[Crossref]

T. A. Elbayoumi, “Nano drug-delivery systems in cancer therapy: gains, pitfalls and considerations in DMPK and PD,” Ther. Deliv. 1(2), 215–219 (2010).
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A. Rai, A. Prabhune, and C. C. Perry, “Antibiotic mediated synthesis of gold nanoparticles with potent antimicrobial activity and their application in antimicrobial coatings,” J. Mater. Chem. 20(32), 6789–6798 (2010).
[Crossref]

2009 (10)

G. L. Burygin, B. N. Khlebtsov, A. N. Shantrokha, L. A. Dykman, V. A. Bogatyrev, and N. G. Khlebtsov, “On the enhanced antibacterial activity of antibiotics mixed with gold nanoparticles,” Nanoscale Res. Lett. 4(8), 794–801 (2009).
[Crossref] [PubMed]

E. Boisselier and D. Astruc, “Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity,” Chem. Soc. Rev. 38(6), 1759–1782 (2009).
[Crossref] [PubMed]

S. S. Agasti, A. Chompoosor, C. C. You, P. Ghosh, C. K. Kim, and V. M. Rotello, “Photoregulated release of caged anticancer drugs from gold nanoparticles,” J. Am. Chem. Soc. 131(16), 5728–5729 (2009).
[Crossref] [PubMed]

S. Dhar, W. L. Daniel, D. A. Giljohann, C. A. Mirkin, and S. J. Lippard, “Polyvalent oligonucleotide gold nanoparticle conjugates as delivery vehicles for platinum(IV) warheads,” J. Am. Chem. Soc. 131(41), 14652–14653 (2009).
[Crossref] [PubMed]

L. Hosta, M. Pla-Roca, J. Arbiol, C. López-Iglesias, J. Samitier, L. J. Cruz, M. J. Kogan, and F. Albericio, “Conjugation of Kahalalide F with gold nanoparticles to enhance in vitro antitumoral activity,” Bioconjug. Chem. 20(1), 138–146 (2009).
[Crossref] [PubMed]

E. C. Dreaden, S. C. Mwakwari, Q. H. Sodji, A. K. Oyelere, and M. A. El-Sayed, “Tamoxifen-poly(ethylene glycol)-thiol gold nanoparticle conjugates: enhanced potency and selective delivery for breast cancer treatment,” Bioconjug. Chem. 20(12), 2247–2253 (2009).
[Crossref] [PubMed]

M. Eghtedari, A. V. Liopo, J. A. Copland, A. A. Oraevsky, and M. Motamedi, “Engineering of hetero-functional gold nanorods for the in vivo molecular targeting of breast cancer cells,” Nano Lett. 9(1), 287–291 (2009).
[Crossref] [PubMed]

C. Park, H. Youn, H. Kim, T. Noh, Y. H. Kook, E. T. Oh, H. J. Park, and C. Kim, “Cyclodextrin-covered gold nanoparticles for targeted delivery of an anti-cancer drug,” J. Mater. Chem. 19(16), 2310–2315 (2009).
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G. Li, D. Li, L. Zhang, J. Zhai, and E. Wang, “One-step synthesis of folic acid protected gold nanoparticles and their receptor-mediated intracellular uptake,” Chemistry 15(38), 9868–9873 (2009).
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W. C. Huang, P.-J. Tsai, and Y.-C. Chen, “Multifunctional Fe3O4@Au nanoeggs as photothermal agents for selective killing of nosocomial and antibiotic-resistant bacteria,” Small 5(1), 51–56 (2009).
[Crossref] [PubMed]

2008 (10)

J. Lee, J. Yang, H. Ko, S. J. Oh, J. Kang, J.-H. Son, K. Lee, S.-W. Lee, H.-G. Yoon, J.-S. Suh, Y.-M. Huh, and S. Haam, “Multifunctional magnetic gold nanocomposites: human epithelial cancer detection via magnetic resonance imaging and localized synchronous therapy,” Adv. Funct. Mater. 18(2), 258–264 (2008).
[Crossref]

W. Jiang, B. Y. S. Kim, J. T. Rutka, and W. C. W. Chan, “Nanoparticle-mediated cellular response is size-dependent,” Nat. Nanotechnol. 3(3), 145–150 (2008).
[Crossref] [PubMed]

L. Au, D. Zheng, F. Zhou, Z. Y. Li, X. Li, and Y. Xia, “A quantitative study on the photothermal effect of immuno gold nanocages targeted to breast cancer cells,” ACS Nano 2(8), 1645–1652 (2008).
[Crossref] [PubMed]

D. L. Chamberland, A. Agarwal, N. Kotov, J. Brian Fowlkes, P. L. Carson, and X. Wang, “Photoacoustic tomography of joints aided by an Etanercept-conjugated gold nanoparticle contrast agent-an ex vivo preliminary rat study,” Nanotechnology 19(9), 095101 (2008).
[Crossref] [PubMed]

M. C. Bowman, T. E. Ballard, C. J. Ackerson, D. L. Feldheim, D. M. Margolis, and C. Melander, “Inhibition of HIV fusion with multivalent gold nanoparticles,” J. Am. Chem. Soc. 130(22), 6896–6897 (2008).
[Crossref] [PubMed]

C. R. Patra, R. Bhattacharya, E. Wang, A. Katarya, J. S. Lau, S. Dutta, M. Muders, S. Wang, S. A. Buhrow, S. L. Safgren, M. J. Yaszemski, J. M. Reid, M. M. Ames, P. Mukherjee, and D. Mukhopadhyay, “Targeted delivery of gemcitabine to pancreatic adenocarcinoma using cetuximab as a targeting agent,” Cancer Res. 68(6), 1970–1978 (2008).
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P. Podsiadlo, V. A. Sinani, J. H. Bahng, N. W. Kam, J. Lee, and N. A. Kotov, “Gold nanoparticles enhance the anti-leukemia action of a 6-mercaptopurine chemotherapeutic agent,” Langmuir 24(2), 568–574 (2008).
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E. M. S. Azzam and S. M. I. Morsy, “Enhancement of the antitumour activity for the synthesised dodecylcysteine surfactant using gold nanoparticles,” J. Surf. Deterg. 11(3), 195–199 (2008).
[Crossref]

M. Stiti, A. Cecchi, M. Rami, M. Abdaoui, V. Barragan-Montero, A. Scozzafava, Y. Guari, J. Y. Winum, and C. T. Supuran, “Carbonic anhydrase inhibitor coated gold nanoparticles selectively inhibit the tumor-associated isoform IX over the cytosolic isozymes I and II,” J. Am. Chem. Soc. 130(48), 16130–16131 (2008).
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Y. Cheng, A. C Samia, J. D. Meyers, I. Panagopoulos, B. Fei, and C. Burda, “Highly efficient drug delivery with gold nanoparticle vectors for in vivo photodynamic therapy of cancer,” J. Am. Chem. Soc. 130(32), 10643–10647 (2008).
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2007 (7)

V. Selvaraj and M. Alagar, “Analytical detection and biological assay of antileukemic drug 5-fluorouracil using gold nanoparticles as probe,” Int. J. Pharm. 337(1-2), 275–281 (2007).
[Crossref] [PubMed]

B. Saha, J. Bhattacharya, A. Mukherjee, A. K. Ghosh, C. R. Santra, A. K. Dasgupta, and P. Karmakar, “In vitro structural and functional evaluation of gold nanoparticles conjugated antibiotics,” Nanoscale Res. Lett. 2(12), 614–622 (2007).
[Crossref]

A. N. Grace and K. Pandian, “Antibacterial efficacy of aminoglycosidic antibiotics protected gold nanoparticles – A brief study,” Colloids Surf. A Physicochem. Eng. Asp. 297(1–3), 63–70 (2007).
[Crossref]

Y. H. Chen, C. Y. Tsai, P. Y. Huang, M. Y. Chang, P. C. Cheng, C. H. Chou, D. H. Chen, C. R. Wang, A. L. Shiau, and C. L. Wu, “Methotrexate conjugated to gold nanoparticles inhibits tumor growth in a syngeneic lung tumor model,” Mol. Pharm. 4(5), 713–722 (2007).
[Crossref] [PubMed]

J. Li, X. Wang, C. Wang, B. Chen, Y. Dai, R. Zhang, M. Song, G. Lv, and D. Fu, “The enhancement effect of gold nanoparticles in drug delivery and as biomarkers of drug-resistant cancer cells,” ChemMedChem 2(3), 374–378 (2007).
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Z. Nie, K. J. Liu, C. J. Zhong, L. F. Wang, Y. Yang, Q. Tian, and Y. Liu, “Enhanced radical scavenging activity by antioxidant-functionalized gold nanoparticles: a novel inspiration for development of new artificial antioxidants,” Free Radic. Biol. Med. 43(9), 1243–1254 (2007).
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M. R. Choi, K. J. Stanton-Maxey, J. K. Stanley, C. S. Levin, R. Bardhan, D. Akin, S. Badve, J. Sturgis, J. P. Robinson, R. Bashir, N. J. Halas, and S. E. Clare, “A cellular Trojan Horse for delivery of therapeutic nanoparticles into tumors,” Nano Lett. 7(12), 3759–3765 (2007).
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2006 (3)

R. K. Visaria, R. J. Griffin, B. W. Williams, E. S. Ebbini, G. F. Paciotti, C. W. Song, and J. C. Bischof, “Enhancement of tumor thermal therapy using gold nanoparticle-assisted tumor necrosis factor-α delivery,” Mol. Cancer Ther. 5(4), 1014–1020 (2006).
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H. M. Joshi, D. R. Bhumkar, K. Joshi, V. Pokharkar, and M. Sastry, “Gold nanoparticles as carriers for efficient transmucosal insulin delivery,” Langmuir 22(1), 300–305 (2006).
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M. J. Rosemary, I. MacLaren, and T. Pradeep, “Investigations of the antibacterial properties of ciprofloxacin@SiO2.,” Langmuir 22(24), 10125–10129 (2006).
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2004 (3)

R. T. Tom, V. Suryanarayanan, P. G. Reddy, S. Baskaran, and T. Pradeep, “Ciprofloxacin-protected gold nanoparticles,” Langmuir 20(5), 1909–1914 (2004).
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G. F. Paciotti, L. Myer, D. Weinreich, D. Goia, N. Pavel, R. E. McLaughlin, and L. Tamarkin, “Colloidal gold: a novel nanoparticle vector for tumor directed drug delivery,” Drug Deliv. 11(3), 169–183 (2004).
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L. A. Dykman, M. V. Sumaroka, S. A. Staroverov, I. S. Zaĭtseva, and V. A. Bogatyrev, “[Immunogenic properties of the colloidal gold],” Izv. Akad. Nauk Ser. Biol. 31(1), 86–91 (2004).
[PubMed]

2003 (1)

H. Gu, P. L. Ho, E. Tong, L. Wang, and B. Xu, “Presenting vancomycin on nanoparticles to enhance antimicrobial activities,” Nano Lett. 3(9), 1261–1263 (2003).
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2001 (1)

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G. L. Burygin, B. N. Khlebtsov, A. N. Shantrokha, L. A. Dykman, V. A. Bogatyrev, and N. G. Khlebtsov, “On the enhanced antibacterial activity of antibiotics mixed with gold nanoparticles,” Nanoscale Res. Lett. 4(8), 794–801 (2009).
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M. Khoobchandani, K. Katti, A. Maxwell, W. P. Fay, and K. V. Katti, “Laminin receptor-avid nanotherapeutic EGCg-AuNPs as a potential alternative therapeutic approach to prevent restenosis,” Int. J. Mol. Sci. 17(3), 316 (2016).
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H. Norouzi, K. Khoshgard, and F. Akbarzadeh, “In vitro outlook of gold nanoparticles in photo-thermal therapy: a literature review,” Lasers Med. Sci. 33(4), 917–926 (2018).
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Khosravi, Z.

J. Beik, M. Khateri, Z. Khosravi, S. K. Kamrava, S. Kooranifar, H. Ghaznavi, and A. Shakeri-Zadeh, “Gold nanoparticles in combinatorial cancer therapy strategies,” Coord. Chem. Rev. 387, 299–324 (2019).
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E. C. Dreaden, S. C. Mwakwari, L. A. Austin, M. J. Kieffer, A. K. Oyelere, and M. A. El-Sayed, “Small molecule-gold nanorod conjugates selectively target and induce macrophage cytotoxicity towards breast cancer cells,” Small 8(18), 2819–2822 (2012).
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M. Schomaker, D. Killian, S. Willenbrock, D. Heinemann, S. Kalies, A. Ngezahayo, I. Nolte, T. Ripken, C. Junghanß, H. Meyer, H. Murua Escobar, and A. Heisterkamp, “Biophysical effects in off-resonant gold nanoparticle mediated (GNOME) laser transfection of cell lines, primary- and stem cells using fs laser pulses,” J. Biophotonics 8(8), 646–658 (2015).
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W. Jiang, B. Y. S. Kim, J. T. Rutka, and W. C. W. Chan, “Nanoparticle-mediated cellular response is size-dependent,” Nat. Nanotechnol. 3(3), 145–150 (2008).
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Kim, B.-S.

H. Lee, M.-Y. Lee, S. H. Bhang, B.-S. Kim, Y. S. Kim, J. H. Ju, K. S. Kim, and S. K. Hahn, “Hyaluronate-gold nanoparticle/tocilizumab complex for the treatment of rheumatoid arthritis,” ACS Nano 8(5), 4790–4798 (2014).
[Crossref] [PubMed]

J. Nam, W.-G. La, S. Hwang, Y. S. Ha, N. Park, N. Won, S. Jung, S. H. Bhang, Y.-J. Ma, Y.-M. Cho, M. Jin, J. Han, J.-Y. Shin, E. K. Wang, S. G. Kim, S.-H. Cho, J. Yoo, B.-S. Kim, and S. Kim, “pH-responsive assembly of gold nanoparticles and “spatiotemporally concerted” drug release for synergistic cancer therapy,” ACS Nano 7(4), 3388–3402 (2013).
[Crossref] [PubMed]

Kim, C.

C. Park, H. Youn, H. Kim, T. Noh, Y. H. Kook, E. T. Oh, H. J. Park, and C. Kim, “Cyclodextrin-covered gold nanoparticles for targeted delivery of an anti-cancer drug,” J. Mater. Chem. 19(16), 2310–2315 (2009).
[Crossref]

Kim, C. K.

S. S. Agasti, A. Chompoosor, C. C. You, P. Ghosh, C. K. Kim, and V. M. Rotello, “Photoregulated release of caged anticancer drugs from gold nanoparticles,” J. Am. Chem. Soc. 131(16), 5728–5729 (2009).
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Kim, D.

S. Ahn, I. H. Lee, S. Kang, D. Kim, M. Choi, P. E. Saw, E. C. Shin, and S. Jon, “Gold nanoparticles displaying tumor-associated self-antigens as a potential vaccine for cancer immunotherapy,” Adv. Healthc. Mater. 3(8), 1194–1199 (2014).
[Crossref] [PubMed]

I. H. Lee, H. K. Kwon, S. An, D. Kim, S. Kim, M. K. Yu, J. H. Lee, T. S. Lee, S. H. Im, and S. Jon, “Imageable antigen-presenting gold nanoparticle vaccines for effective cancer immunotherapy in vivo,” Angew. Chem. Int. Ed. Engl. 51(35), 8800–8805 (2012).
[Crossref] [PubMed]

Kim, D. S.

T. H. Tran, R. K. Thapa, H. T. Nguyen, T. T. Pham, T. Ramasamy, D. S. Kim, C. S. Yong, J. O. Kim, and H.-G. Choi, “Combined phototherapy in anti-cancer treatment: therapeutics design and perspectives,” J. Pharm. Investig. 46(6), 505–517 (2016).
[Crossref]

Kim, H.

H. Kim, V. P. Nguyen, P. Manivasagan, M. J. Jung, S. W. Kim, J. Oh, and H. W. Kang, “Doxorubicin-fucoidan-gold nanoparticles composite for dual-chemo-photothermal treatment on eye tumors,” Oncotarget 8(69), 113719 (2017).
[Crossref] [PubMed]

S. Kang, S. Ahn, J. Lee, J. Y. Kim, M. Choi, V. Gujrati, H. Kim, J. Kim, E.-C. Shin, and S. Jon, “Effects of gold nanoparticle-based vaccine size on lymph node delivery and cytotoxic T-lymphocyte responses,” J. Control. Release 256, 56–67 (2017).
[Crossref] [PubMed]

C. Park, H. Youn, H. Kim, T. Noh, Y. H. Kook, E. T. Oh, H. J. Park, and C. Kim, “Cyclodextrin-covered gold nanoparticles for targeted delivery of an anti-cancer drug,” J. Mater. Chem. 19(16), 2310–2315 (2009).
[Crossref]

Kim, H. B.

L. T. Arayan, H. B. Kim, A. W. Bernardo Reyes, N. T. Xuan Huy, I. H. Hong, K. Lee, J.-H. Yeom, Y. Park, and S. Kim, “The immunomodulatory effect of antimicrobial peptide HPA3P restricts Brucella abortus 544 infection in BALB/c mice,” Vet. Microbiol. 225, 17–24 (2018).
[Crossref] [PubMed]

Kim, H. J.

K. Lee, M. Conboy, H. M. Park, F. Jiang, H. J. Kim, M. A. Dewitt, V. A. Mackley, K. Chang, A. Rao, C. Skinner, T. Shobha, M. Mehdipour, H. Liu, W. C. Huang, F. Lan, N. L. Bray, S. Li, J. E. Corn, K. Kataoka, J. A. Doudna, I. Conboy, and N. Murthy, “Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair,” Nat. Biomed. Eng. 1(11), 889–901 (2017).
[Crossref] [PubMed]

Kim, H. S.

M. Zhang, H. S. Kim, T. Jin, J. Woo, Y. J. Piao, and W. K. Moon, “Near-infrared photothermal therapy using anti-EGFR-gold nanorod conjugates for triple negative breast cancer,” Oncotarget 8(49), 86566–86575 (2017).
[Crossref] [PubMed]

Kim, H.-W.

S. Baek, R. K. Singh, T.-H. Kim, J.-W. Seo, U. S. Shin, W. Chrzanowski, and H.-W. Kim, “Triple hit with drug carriers: pH- and temperature-responsive theranostics for multimodal chemo- and photothermal-therapy and diagnostic applications,” ACS Appl. Mater. Interfaces 8(14), 8967–8979 (2016).
[Crossref] [PubMed]

Kim, J.

S. Kang, S. Ahn, J. Lee, J. Y. Kim, M. Choi, V. Gujrati, H. Kim, J. Kim, E.-C. Shin, and S. Jon, “Effects of gold nanoparticle-based vaccine size on lymph node delivery and cytotoxic T-lymphocyte responses,” J. Control. Release 256, 56–67 (2017).
[Crossref] [PubMed]

Kim, J. O.

T. Ramasamy, H. B. Ruttala, P. Sundaramoorthy, B. K. Poudel, Y. S. Youn, S. K. Ku, H.-G. Choi, C. S. Yong, and J. O. Kim, “Multimodal selenium nanoshell-capped Au@mSiO2 nanoplatform for NIR-responsive chemo-photothermal therapy against metastatic breast cancer,” NPG Asia Mater. 10(4), 197–216 (2018).
[Crossref]

B. K. Poudel, B. Gupta, T. Ramasamy, R. K. Thapa, S. Pathak, K. T. Oh, J. H. Jeong, H. G. Choi, C. S. Yong, and J. O. Kim, “PEGylated thermosensitive lipid-coated hollow gold nanoshells for effective combinational chemo-photothermal therapy of pancreatic cancer,” Colloids Surf. B Biointerfaces 160, 73–83 (2017).
[Crossref] [PubMed]

T. H. Tran, R. K. Thapa, H. T. Nguyen, T. T. Pham, T. Ramasamy, D. S. Kim, C. S. Yong, J. O. Kim, and H.-G. Choi, “Combined phototherapy in anti-cancer treatment: therapeutics design and perspectives,” J. Pharm. Investig. 46(6), 505–517 (2016).
[Crossref]

Kim, J. W.

J. Shao, R. J. Griffin, E. I. Galanzha, J. W. Kim, N. Koonce, J. Webber, T. Mustafa, A. S. Biris, D. A. Nedosekin, and V. P. Zharov, “Photothermal nanodrugs: potential of TNF-gold nanospheres for cancer theranostics,” Sci. Rep. 3(1), 1293 (2013).
[Crossref] [PubMed]

Kim, J. Y.

S. Kang, S. Ahn, J. Lee, J. Y. Kim, M. Choi, V. Gujrati, H. Kim, J. Kim, E.-C. Shin, and S. Jon, “Effects of gold nanoparticle-based vaccine size on lymph node delivery and cytotoxic T-lymphocyte responses,” J. Control. Release 256, 56–67 (2017).
[Crossref] [PubMed]

Kim, J.-H.

S. Gurunathan and J.-H. Kim, “Biocompatible gold nanoparticles ameliorate retinoic acid-induced cell death and induce differentiation in F9 teratocarcinoma stem cells,” Nanomaterials (Basel) 8(6), 396 (2018).
[Crossref] [PubMed]

Y. E. Hur, S. Kim, J.-H. Kim, S.-H. Cha, M.-J. Choi, S. Cho, and Y. Park, “One-step functionalization of gold and silver nanoparticles by ampicillin,” Mater. Lett. 129, 185–190 (2014).
[Crossref]

Kim, K.

H. Y. Yoon, S. T. Selvan, Y. Yang, M. J. Kim, D. K. Yi, I. C. Kwon, and K. Kim, “Engineering nanoparticle strategies for effective cancer immunotherapy,” Biomaterials 178, 597–607 (2018).
[Crossref] [PubMed]

Kim, K. S.

H. Lee, M.-Y. Lee, S. H. Bhang, B.-S. Kim, Y. S. Kim, J. H. Ju, K. S. Kim, and S. K. Hahn, “Hyaluronate-gold nanoparticle/tocilizumab complex for the treatment of rheumatoid arthritis,” ACS Nano 8(5), 4790–4798 (2014).
[Crossref] [PubMed]

Kim, M. J.

H. Y. Yoon, S. T. Selvan, Y. Yang, M. J. Kim, D. K. Yi, I. C. Kwon, and K. Kim, “Engineering nanoparticle strategies for effective cancer immunotherapy,” Biomaterials 178, 597–607 (2018).
[Crossref] [PubMed]

Kim, S.

L. T. Arayan, H. B. Kim, A. W. Bernardo Reyes, N. T. Xuan Huy, I. H. Hong, K. Lee, J.-H. Yeom, Y. Park, and S. Kim, “The immunomodulatory effect of antimicrobial peptide HPA3P restricts Brucella abortus 544 infection in BALB/c mice,” Vet. Microbiol. 225, 17–24 (2018).
[Crossref] [PubMed]

Y. E. Hur, S. Kim, J.-H. Kim, S.-H. Cha, M.-J. Choi, S. Cho, and Y. Park, “One-step functionalization of gold and silver nanoparticles by ampicillin,” Mater. Lett. 129, 185–190 (2014).
[Crossref]

J. Nam, W.-G. La, S. Hwang, Y. S. Ha, N. Park, N. Won, S. Jung, S. H. Bhang, Y.-J. Ma, Y.-M. Cho, M. Jin, J. Han, J.-Y. Shin, E. K. Wang, S. G. Kim, S.-H. Cho, J. Yoo, B.-S. Kim, and S. Kim, “pH-responsive assembly of gold nanoparticles and “spatiotemporally concerted” drug release for synergistic cancer therapy,” ACS Nano 7(4), 3388–3402 (2013).
[Crossref] [PubMed]

I. H. Lee, H. K. Kwon, S. An, D. Kim, S. Kim, M. K. Yu, J. H. Lee, T. S. Lee, S. H. Im, and S. Jon, “Imageable antigen-presenting gold nanoparticle vaccines for effective cancer immunotherapy in vivo,” Angew. Chem. Int. Ed. Engl. 51(35), 8800–8805 (2012).
[Crossref] [PubMed]

Kim, S. G.

J. Nam, W.-G. La, S. Hwang, Y. S. Ha, N. Park, N. Won, S. Jung, S. H. Bhang, Y.-J. Ma, Y.-M. Cho, M. Jin, J. Han, J.-Y. Shin, E. K. Wang, S. G. Kim, S.-H. Cho, J. Yoo, B.-S. Kim, and S. Kim, “pH-responsive assembly of gold nanoparticles and “spatiotemporally concerted” drug release for synergistic cancer therapy,” ACS Nano 7(4), 3388–3402 (2013).
[Crossref] [PubMed]

Kim, S. W.

H. Kim, V. P. Nguyen, P. Manivasagan, M. J. Jung, S. W. Kim, J. Oh, and H. W. Kang, “Doxorubicin-fucoidan-gold nanoparticles composite for dual-chemo-photothermal treatment on eye tumors,” Oncotarget 8(69), 113719 (2017).
[Crossref] [PubMed]

Kim, T.-H.

S. Baek, R. K. Singh, T.-H. Kim, J.-W. Seo, U. S. Shin, W. Chrzanowski, and H.-W. Kim, “Triple hit with drug carriers: pH- and temperature-responsive theranostics for multimodal chemo- and photothermal-therapy and diagnostic applications,” ACS Appl. Mater. Interfaces 8(14), 8967–8979 (2016).
[Crossref] [PubMed]

Kim, Y. S.

H. Lee, M.-Y. Lee, S. H. Bhang, B.-S. Kim, Y. S. Kim, J. H. Ju, K. S. Kim, and S. K. Hahn, “Hyaluronate-gold nanoparticle/tocilizumab complex for the treatment of rheumatoid arthritis,” ACS Nano 8(5), 4790–4798 (2014).
[Crossref] [PubMed]

Y. M. Park, S. J. Lee, Y. S. Kim, M. H. Lee, G. S. Cha, I. D. Jung, T. H. Kang, and H. D. Han, “Nanoparticle-based vaccine delivery for cancer immunotherapy,” Immune Netw. 13(5), 177–183 (2013).
[Crossref] [PubMed]

Kim, Y.-S.

H. A. Andersson, Y.-S. Kim, B. E. O’Neill, Z.-Z. Shi, and R. E. Serda, “HSP70 promoter-driven activation of gene expression for immunotherapy using gold nanorods and near infrared light,” Vaccines (Basel) 2(2), 216–227 (2014).
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O. Bibikova, P. Singh, A. Popov, G. Akchurin, A. Skaptsov, I. Skovorodkin, V. Khanadeev, D. Mikhalevich, M. Kinnunen, G. Akchurin, V. Bogatyrev, N. Khlebtsov, S. J. Vainio, I. Meglinski, and V. Tuchin, “Shape-dependent interaction of gold nanoparticles with cultured cells at laser exposure,” Laser Phys. Lett. 14(5), 055901 (2017).
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S. A. Staroverov, O. A. Gasina, A. A. Kladiev, and V. A. Bogatyrev, “The impact of complex prospidin–colloidal gold on tumor cells,” Russian Journal of Biotherapy 9(3), 22–23 (2010).

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K. Sztandera, M. Gorzkiewicz, and B. Klajnert-Maculewicz, “Gold nanoparticles in cancer treatment,” Mol. Pharm. 16(1), 1–23 (2019).
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N. Rattanata, S. Klaynongsruang, C. Leelayuwat, T. Limpaiboon, A. Lulitanond, P. Boonsiri, S. Chio-Srichan, S. Soontaranon, S. Rugmai, and J. Daduang, “Gallic acid conjugated with gold nanoparticles: antibacterial activity and mechanism of action on foodborne pathogens,” Int. J. Nanomedicine 11(11), 3347–3356 (2016).
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J. Lee, J. Yang, H. Ko, S. J. Oh, J. Kang, J.-H. Son, K. Lee, S.-W. Lee, H.-G. Yoon, J.-S. Suh, Y.-M. Huh, and S. Haam, “Multifunctional magnetic gold nanocomposites: human epithelial cancer detection via magnetic resonance imaging and localized synchronous therapy,” Adv. Funct. Mater. 18(2), 258–264 (2008).
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L. Hosta, M. Pla-Roca, J. Arbiol, C. López-Iglesias, J. Samitier, L. J. Cruz, M. J. Kogan, and F. Albericio, “Conjugation of Kahalalide F with gold nanoparticles to enhance in vitro antitumoral activity,” Bioconjug. Chem. 20(1), 138–146 (2009).
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A. Barhoumi, W. Wang, D. Zurakowski, R. S. Langer, and D. S. Kohane, “Photothermally targeted thermosensitive polymer-masked nanoparticles,” Nano Lett. 14(7), 3697–3701 (2014).
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X. Li, M. Takashima, E. Yuba, A. Harada, and K. Kono, “PEGylated PAMAM dendrimer-doxorubicin conjugate-hybridized gold nanorod for combined photothermal-chemotherapy,” Biomaterials 35(24), 6576–6584 (2014).
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Kook, Y. H.

C. Park, H. Youn, H. Kim, T. Noh, Y. H. Kook, E. T. Oh, H. J. Park, and C. Kim, “Cyclodextrin-covered gold nanoparticles for targeted delivery of an anti-cancer drug,” J. Mater. Chem. 19(16), 2310–2315 (2009).
[Crossref]

Koonce, N.

J. Shao, R. J. Griffin, E. I. Galanzha, J. W. Kim, N. Koonce, J. Webber, T. Mustafa, A. S. Biris, D. A. Nedosekin, and V. P. Zharov, “Photothermal nanodrugs: potential of TNF-gold nanospheres for cancer theranostics,” Sci. Rep. 3(1), 1293 (2013).
[Crossref] [PubMed]

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J. Beik, M. Khateri, Z. Khosravi, S. K. Kamrava, S. Kooranifar, H. Ghaznavi, and A. Shakeri-Zadeh, “Gold nanoparticles in combinatorial cancer therapy strategies,” Coord. Chem. Rev. 387, 299–324 (2019).
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L. Rastogi, A. J. Kora, and A. Arunachalam, “Highly stable, protein capped gold nanoparticles as effective drug delivery vehicles for amino-glycosidic antibiotics,” Mater. Sci. Eng. C 32(6), 1571–1577 (2012).
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K. B. Vang, I. Safina, E. Darrigues, D. Nedosekin, Z. A. Nima, W. Majeed, F. Watanabe, G. Kannarpady, R. A. Kore, D. Casciano, V. P. Zharov, R. J. Griffin, R. P. M. Dings, and A. S. Biris, “Modifying dendritic cell activation with plasmonic nano vectors,” Sci. Rep. 7(1), 5513 (2017).
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S. Kalita, R. Kandimalla, K. K. Sharma, A. C. Kataki, M. Deka, and J. Kotoky, “Amoxicillin functionalized gold nanoparticles reverts MRSA resistance,” Mater. Sci. Eng. C 61, 720–727 (2016).
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D. L. Chamberland, A. Agarwal, N. Kotov, J. Brian Fowlkes, P. L. Carson, and X. Wang, “Photoacoustic tomography of joints aided by an Etanercept-conjugated gold nanoparticle contrast agent-an ex vivo preliminary rat study,” Nanotechnology 19(9), 095101 (2008).
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P. Podsiadlo, V. A. Sinani, J. H. Bahng, N. W. Kam, J. Lee, and N. A. Kotov, “Gold nanoparticles enhance the anti-leukemia action of a 6-mercaptopurine chemotherapeutic agent,” Langmuir 24(2), 568–574 (2008).
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B. Englinger, C. Pirker, P. Heffeter, A. Terenzi, C. R. Kowol, B. K. Keppler, and W. Berger, “Metal drugs and the anticancer immune response,” Chem. Rev. 119(2), 1519–1624 (2019).
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M. Hembury, C. Chiappini, S. Bertazzo, T. L. Kalber, G. L. Drisko, O. Ogunlade, S. Walker-Samuel, K. S. Krishna, C. Jumeaux, P. Beard, C. S. Kumar, A. E. Porter, M. F. Lythgoe, C. Boissière, C. Sanchez, and M. M. Stevens, “Gold-silica quantum rattles for multimodal imaging and therapy,” Proc. Natl. Acad. Sci. U.S.A. 112(7), 1959–1964 (2015).
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T. Ramasamy, H. B. Ruttala, P. Sundaramoorthy, B. K. Poudel, Y. S. Youn, S. K. Ku, H.-G. Choi, C. S. Yong, and J. O. Kim, “Multimodal selenium nanoshell-capped Au@mSiO2 nanoplatform for NIR-responsive chemo-photothermal therapy against metastatic breast cancer,” NPG Asia Mater. 10(4), 197–216 (2018).
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J. Nam, S. Son, L. J. Ochyl, R. Kuai, A. Schwendeman, and J. J. Moon, “Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer,” Nat. Commun. 9(1), 1074 (2018).
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S. Saha, X. Xiong, P. K. Chakraborty, K. Shameer, R. R. Arvizo, R. A. Kudgus, S. K. D. Dwivedi, M. N. Hossen, E. M. Gillies, J. D. Robertson, J. T. Dudley, R. A. Urrutia, R. G. Postier, R. Bhattacharya, and P. Mukherjee, “Gold nanoparticle reprograms pancreatic tumor microenvironment and inhibits tumor growth,” ACS Nano 10(12), 10636–10651 (2016).
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A. Kumar, H. Ma, X. Zhang, K. Huang, S. Jin, J. Liu, T. Wei, W. Cao, G. Zou, and X.-J. Liang, “Gold nanoparticles functionalized with therapeutic and targeted peptides for cancer treatment,” Biomaterials 33(4), 1180–1189 (2012).
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Kumar, C. S.

C. S. Kumar, A. Mahesh, M. G. Antoniraj, S. Vaidevi, and K. Ruckmani, “Ultrafast synthesis of stabilized gold nanoparticles using aqueous fruit extract of Limonia acidissima L. and conjugated epirubicin: targeted drug delivery for treatment of breast cancer,” RSC Advances 6(32), 26874–26882 (2016).
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Kumar, D.

M. Moghiseh, C. Lowe, J. G. Lewis, D. Kumar, A. Butler, N. Anderson, and A. Raja, “Spectral photon-counting molecular imaging for quantification of monoclonal antibody-conjugated gold nanoparticles targeted to lymphoma and breast cancer: an in vitro study,” Contrast Media Mol. Imaging 2018, 2136840 (2018).
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Kurisu, J.

H. Nakatsuji, K. Kawabata Galbraith, J. Kurisu, H. Imahori, T. Murakami, and M. Kengaku, “Surface chemistry for cytosolic gene delivery and photothermal transgene expression by gold nanorods,” Sci. Rep. 7(1), 4694 (2017).
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Kurumaddali, A.

S. Labala, P. K. Mandapalli, A. Kurumaddali, and V. V. K. Venuganti, “Layer-by-layer polymer coated gold nanoparticles for topical delivery of imatinib mesylate to treat melanoma,” Mol. Pharm. 12(3), 878–888 (2015).
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Kwon, H. K.

I. H. Lee, H. K. Kwon, S. An, D. Kim, S. Kim, M. K. Yu, J. H. Lee, T. S. Lee, S. H. Im, and S. Jon, “Imageable antigen-presenting gold nanoparticle vaccines for effective cancer immunotherapy in vivo,” Angew. Chem. Int. Ed. Engl. 51(35), 8800–8805 (2012).
[Crossref] [PubMed]

Kwon, I. C.

H. Y. Yoon, S. T. Selvan, Y. Yang, M. J. Kim, D. K. Yi, I. C. Kwon, and K. Kim, “Engineering nanoparticle strategies for effective cancer immunotherapy,” Biomaterials 178, 597–607 (2018).
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Kwon, I. K.

D. N. Heo, D. H. Yang, H.-J. Moon, J. B. Lee, M. S. Bae, S. C. Lee, W. J. Lee, I.-C. Sun, and I. K. Kwon, “Gold nanoparticles surface-functionalized with paclitaxel drug and biotin receptor as theranostic agents for cancer therapy,” Biomaterials 33(3), 856–866 (2012).
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J. Nam, W.-G. La, S. Hwang, Y. S. Ha, N. Park, N. Won, S. Jung, S. H. Bhang, Y.-J. Ma, Y.-M. Cho, M. Jin, J. Han, J.-Y. Shin, E. K. Wang, S. G. Kim, S.-H. Cho, J. Yoo, B.-S. Kim, and S. Kim, “pH-responsive assembly of gold nanoparticles and “spatiotemporally concerted” drug release for synergistic cancer therapy,” ACS Nano 7(4), 3388–3402 (2013).
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S. Labala, P. K. Mandapalli, A. Kurumaddali, and V. V. K. Venuganti, “Layer-by-layer polymer coated gold nanoparticles for topical delivery of imatinib mesylate to treat melanoma,” Mol. Pharm. 12(3), 878–888 (2015).
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