Infrared spectra of selected regions of normal, cirrhotic, and neoplastic liver tissue samples are reported. Spectra of these tissues may vary for a number of reasons that may or may not be related to the state of health or disease. With the use of histochemical and immunohistochemical methods, the spectral variations are interpreted in terms of the biochemical and pathological processes involved. This paper lays the groundwork for correlation of infrared spectroscopic and pathological/histochemical results for other tissues, to be reported in subsequent communications.

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