Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group
  • Applied Spectroscopy
  • Vol. 53,
  • Issue 1,
  • pp. 74-81
  • (1999)

Elemental Analysis of Individual Combinatorial Chemistry Library Members by Energy-Dispersive X-ray Spectroscopy

Not Accessible

Your library or personal account may give you access

Abstract

Elemental analysis of single combinatorial chemistry library members bound to polystyrene beads was studied by energy-dispersive X-ray spectroscopy (EDS) on a scanning electron microscope (SEM). The effects of bead geometry and electron beam exposure time on the elemental analysis results were evaluated. Elemental analysis data were highly variable on round beads, but reliable concentration data could be obtained from flattened beads held in silicon wafer bead holders. The duration of exposure time on flattened beads had no effect on elemental concentration data for the compounds studied. EDS analysis of single beads provided results similar to those obtained by combustion analysis. In summary, elemental analysis of single combinatorial chemistry library members by EDS was shown to be a reliable and fast method of analysis of single beads.

PDF Article
More Like This
Laser-driven photoelectron induced pulsed X-ray source for energy dispersive X-ray spectroscopy and radiography applications

S. Ullah, Z. U. Rehman, U. Khurshid, H. Qayyum, A. H. Dogar, and A. Qayyum
Appl. Opt. 60(9) 2604-2609 (2021)

Quantitative elemental analysis of high silica bauxite using calibration-free laser-induced breakdown spectroscopy

Muhammad Fahad, Sajjad Ali, Khizar Hussain Shah, Asim Shahzad, and Muhammad Abrar
Appl. Opt. 58(27) 7588-7596 (2019)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved