Abstract

Artifacts, or spurious signals, are common problems in the measurement of optical activity. Until recently they have limited the applicability of vibrational circular dichroism (VCD) in cases of weak ellipticity—for example, in structural studies of small peptides. The artifacts in dispersive VCD to be discussed here can be from the optical and electronic hardware as well as from the data processing methods in the software. The data acquisition and processing methods reported here reduce system artifacts in VCD measurements, particularly for samples with weak ellipticity.

Artifact-free balanced detection for the measurement of circular dichroism with a sub-picosecond time resolution

Pascale Changenet and François Hache
Opt. Express 31(13) 21296-21310 (2023)

A picosecond time-resolved vibrational circular dichroism spectrometer

Mathias Bonmarin and Jan Helbing
Opt. Lett. 33(18) 2086-2088 (2008)

Method for artifact-free circular dichroism measurements based on polarization grating

Clementina Provenzano, Pasquale Pagliusi, Alfredo Mazzulla, and Gabriella Cipparrone
Opt. Lett. 35(11) 1822-1824 (2010)

Ultrafast broadband circular dichroism in the deep ultraviolet

Malte Oppermann, Benjamin Bauer, Thomas Rossi, Francesco Zinna, Jan Helbing, Jérôme Lacour, and Majed Chergui
Optica 6(1) 56-60 (2019)

Optimized interferometric setup for chiral and achiral ultrafast IR spectroscopy

Biplab Dutta and Jan Helbing
Opt. Express 23(12) 16449-16465 (2015)