Abstract

In the course of operating process equipment in the pharmaceutical industry, it is necessary to assure that all product contact surfaces of process equipment contain a minimum amount of residue. The residue may be another product remaining from a previous operation, an excipient, or a "nonformulation" type of material. This report discusses the determination of hydrocarbons, in the form of lubricating greases, on the product contact surface of various tablet presses by use of FT-IR spectroscopy. The FT-IR spectroscopic method provides for both identification and quantitation of the lubricant and was suggested by an EPA method.

PDF Article

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.