Abstract

Raman spectroscopy, which has been employed extensively to study the structure and function of biological materials for the last two decades, also has considerable potential as a diagnostic and analytical tool in medicine. However, the medical application of Raman spectroscopy has been limited to some special topics such as lens research because most morbid materials emit strong fluorescence and are weak with respect to laser illumination. Fluorescence and decomposition, two major drawbacks of Raman spectroscopy which must be circumvented, have made its medical applications difficult.

1064  nm dispersive Raman spectroscopy of tissues with strong near-infrared autofluorescence

Chetan A. Patil, Isaac J. Pence, Chad A. Lieber, and Anita Mahadevan-Jansen
Opt. Lett. 39(2) 303-306 (2014)

Application of a near-infrared laser tweezers Raman spectroscopy system for label-free analysis and differentiation of diabetic red blood cells

Jinyong Lin, Lingdong Shao, Sufang Qiu, Xingwu Huang, Mengmeng Liu, Zuci Zheng, Duo Lin, Yongliang Xu, Zhihua Li, Yao Lin, Rong Chen, and Shangyuan Feng
Biomed. Opt. Express 9(3) 984-993 (2018)

Raman spectroscopy: techniques and applications in the life sciences

Dustin W. Shipp, Faris Sinjab, and Ioan Notingher
Adv. Opt. Photon. 9(2) 315-428 (2017)

Multicomponent blood analysis by near-infrared Raman spectroscopy

Andrew J. Berger, Tae-Woong Koo, Irving Itzkan, Gary Horowitz, and Michael S. Feld
Appl. Opt. 38(13) 2916-2926 (1999)

Near-Infrared Planetary Spectra by Fourier Spectroscopy. I. Instruments and Results

Janine Connes and Pierre Connes
J. Opt. Soc. Am. 56(7) 896-910 (1966)