Abstract

A flow injection sampling system to analyze dilute aqueous solutions by surface-enhanced resonance Raman spectroscopy (SERRS) is described, and critical operating parameters are evaluated. A simple procedure for preparing a silver colloid, which is more homogeneous, stable, and SERS-active than that previously reported and does not require sedimentation, is presented. With the use of crystal violet (CV) as a model analyte, the flow injection system, a Raman micro-probe, and an optical multichannel analyzer (OMA) for detection, high-quality, highly reproducible (coefficient of variation = ±2.37% of mean) Raman spectra for 1 × 10⁻⁶ M solutions of CV were obtained in 1 min, and major spectral peaks were observable down to concentrations of 1 × 10⁻¹² M (~4 × 10⁻¹⁹ g of material). SERRS enhancement and spectral quality were experimentally found to vary significantly with the method of Ag sol preparation and laser excitation wavelength. The system described can rapidly (1-240 s) provide quantitative as well as structural information about very dilute aqueous solutions.

Quantitative analysis of double-stranded DNA amplified by a polymerase chain reaction employing surface-enhanced Raman spectroscopy

X. Dou, T. Takama, Y. Yamaguchi, K. Hirai, H. Yamamoto, S. Doi, and Y. Ozaki
Appl. Opt. 37(4) 759-763 (1998)

Raman enhancement properties of TiO₂/Ag carbon fiber cloth using the ultraviolet-induced method: high sensitivity, flexible and reusable

Ning Sun, Zhenyin Lv, Yong Zhu, and Jie Zhang
Opt. Mater. Express 13(3) 586-597 (2023)

Laser-induced construction of multi-branched CuS nanodendrites with excellent surface-enhanced Raman scattering spectroscopy in repeated applications

Shuang Li, Hua Zhang, Linlin Xu, and Ming Chen
Opt. Express 25(14) 16204-16213 (2017)

Label free hepatitis B detection based on serum derivative surface enhanced Raman spectroscopy combined with multivariate analysis

Yudong Lu, Yisheng Lin, Zuci Zheng, Xiaoqiong Tang, Jinyong Lin, Xiujie Liu, Mengmeng Liu, Guannan Chen, Sufang Qiu, Ting Zhou, Yao Lin, and Shangyuan Feng
Biomed. Opt. Express 9(10) 4755-4766 (2018)

Sensitive determinations of Cu, Pb, Cd, and Cr elements in aqueous solutions using chemical replacement combined with surface-enhanced laser-induced breakdown spectroscopy

X. Y. Yang, Z. Q. Hao, C. M. Li, J. M. Li, R. X. Yi, M. Shen, K. H. Li, L. B. Guo, X. Y. Li, Y. F. Lu, and X. Y. Zeng
Opt. Express 24(12) 13410-13417 (2016)