Abstract

An ultrasonic nebulizer with a piezo-electric transducer and a newly designed and constructed continuous on-line collection station have been adapted as an interface between a reverse-phase microbore high-performance liquid chromatograph (RP-μHPLC) and a diffuse reflectance infrared Fourier transform spectrometer. The collection station incorporates a directional vacuum port for confinement of the nebulized material onto a small area (3 to 5 mm i.d.) of the diamond powder. The inherent desolvation that occurs upon nebulization of the reverse-phase eluant, along with the vacuum collection system and the diamond powder diffuse reflectance substrate, makes possible the continuous on-line collection and FT-IR analysis of the compounds separated by a RP-μHPLC without any type of initial solute extraction.

PDF Article

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription