Abstract
Attenuated Total Reflectance Fourier Transform Infrared (ATR-FTIR) spectra of L-phenylalanine in aqueous solution were recorded in the pH range 0-13. The vibrational molecular spectroscopic study of this amino-acid, a well-known component of human tissue, showed that L-phenylalanine undergoes structural changes under the influence of pH. Characteristic bands of each ionic species were highlighted and the p<i>K</i>a values were determined from IR measurements by using an intensity ratio method. ATR-FTIR spectroscopy appears to be a powerful tool for obtaining valuable information on the building blocks of proteins and for measuring tissue damage in aqueous environments.
PDF Article
More Like This
ATR-FTIR and Raman spectroscopic investigation of the electroporation-mediated transdermal delivery of a nanocarrier system containing an antitumour drug
Boglárka Balázs, Péter Sipos, Corina Danciu, Stefana Avram, Codruta Soica, Cristina Dehelean, Gábor Varju, Gábor Erős, Mária Budai-Szűcs, Szilvia Berkó, and Erzsébet Csányi
Biomed. Opt. Express 7(1) 67-78 (2016)
Cited By
You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Login to access Optica Member Subscription