Abstract

Microfluidic mixing plays a key role in various fields, including biomedicine and chemical engineering. To date, although various approaches for imaging microfluidic mixing have been proposed, they provide only quantitative imaging capability and require exogenous labeling agents. Quantitative phase imaging techniques, however, circumvent these problems and offer label-free quantitative information about concentration maps of microfluidic mixing. We present the quantitative phase imaging of microfluidic mixing in various types of polydimethylsiloxane microfluidic channels with different geometries; the feasibility of the present method was validated by comparing it with the results obtained by theoretical calculation based on Fick’s law.

© 2017 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Three-dimensional molecular mapping in a microfluidic mixing device using fluorescence lifetime imaging

Tom Robinson, Prashant Valluri, Hugh B. Manning, Dylan M. Owen, Ian Munro, Clifford B. Talbot, Christopher Dunsby, John F. Eccleston, Geoff S. Baldwin, Mark A. A. Neil, Andrew J. de Mello, and Paul M. W. French
Opt. Lett. 33(16) 1887-1889 (2008)

Active illumination using a digital micromirror device for quantitative phase imaging

Seungwoo Shin, Kyoohyun Kim, Jonghee Yoon, and YongKeun Park
Opt. Lett. 40(22) 5407-5410 (2015)

Coherent anti-Stokes Raman scattering microscopy for quantitative characterization of mixing and flow in microfluidics

Dawn Schafer, Michiel Müller, Mischa Bonn, David W. M. Marr, Jan van Maarseveen, and Jeff Squier
Opt. Lett. 34(2) 211-213 (2009)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (5)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (3)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription