Abstract

A quantum weak measurement scheme based on a Mach–Zehnder interferometer is proposed to detect the concentration of glucose, bringing this mechanism into the field of biomedical sensing for the first time, to the best of our knowledge. With a Mach–Zehnder interferometer system, we can analyze tiny phase differences between the two paths by measuring spectrum shift. We measured the concentration of glucose with weak measurement to achieve a concentration resolution of 8.98×105  g/L corresponding to a volume refractive index of 1.39×108  RIU, which was more than five times higher than the resolution achieved by conventional interference, 4.99×104  g/L. In the detection of glucose concentration in the blood serum of mice, a resolution of 1.0136×107  g/L for weak measurement was obtained.

© 2016 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Glucose sensor with a Sagnac interference optical system

Tatsuya Kumagai, Yusaku Tottori, Ryusuke Miyata, and Hiroshi Kajioka
Appl. Opt. 53(4) 720-726 (2014)

Fabrication of glucose fiber sensor based on immobilized GOD technique for rapid measurement

Ting-Qian Lin, Yin-Lin Lu, and Cheng-Chih Hsu
Opt. Express 18(26) 27560-27566 (2010)

Optimization of a quantum weak measurement system with its working areas

Yang Xu, Lixuan Shi, Tian Guan, Cuixia Guo, Dongmei Li, Yuxuan Yang, Xiangnan Wang, Luyuan Xie, Yonghong He, and Wenyue Xie
Opt. Express 26(16) 21119-21131 (2018)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (7)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (7)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription