Abstract

The model of a Mueller matrix description of mechanisms of optical anisotropy typical for polycrystalline films of blood plasma—optical activity, birefringence, as well as linear and circular dichroism—is suggested. On this basis, the algorithms of reconstruction of parameters distribution (polarization plane rotations, phase shifts, coefficients of linear and circular dichroism) of the indicated types of anisotropy were found for different spectrally selective ranges. Within the statistical analysis of such distributions, the objective criteria of differentiation of films of blood plasma taken from healthy women and breast cancer patients were determined. From the point of view of probative medicine, the operational characteristics (sensitivity, specificity and accuracy) of the method of Mueller matrix reconstruction of optical anisotropy parameters were found, and its efficiency in diagnostics of breast cancer was demonstrated.

© 2014 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Spatial-frequency selection of complex degree of coherence of laser images of blood plasma in diagnostics and differentiation of pathological states of human organism of various nosology

A. G. Ushenko, P. O. Angelsky, M. Sidor, Yu. F. Marchuk, D. R. Andreychuk, and N. V. Pashkovskaya
Appl. Opt. 53(10) B172-B180 (2014)

Spatial-frequency Fourier polarimetry of human blood plasma in the diagnostics of pathological changes

Liviy I. Vatamanesku, Taras M. Boychuk, and Boris M. Bodnar
Appl. Opt. 51(10) C215-C223 (2012)

Birefringence images of polycrystalline films of human urine in early diagnostics of kidney pathology

A. V. Dubolazov, N. V. Pashkovskaya, Yu. A. Ushenko, Yu. F. Marchuk, V. A. Ushenko, and O. Yu. Novakovskaya
Appl. Opt. 55(12) B85-B90 (2016)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (6)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Tables (2)

You do not have subscription access to this journal. Article tables are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (28)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription