Abstract
Stereotactically placed guidewires are used for indicating the location of a nonpalpable carcinoma in breast-conserving surgery. Pathologists use the end of the embedded guidewire to guide sectioning during intraoperative margin assessment, but they do not currently have a tool to indicate the location of the guidewire end for informed sectioning. We present analysis and experimental testing of two optical methods for localizing the end of an embedded fiber-optic guidewire: the first uses irradiance emitted from the fiber to indicate the location of the guidewire end, while the second system uses the fiber optic to create a photoacoustic pulse for localization. Both systems locate the end of the guidewire within , which ensures that the lesion of interest is bisected during sectioning. The accuracy of the irradiance-based beacon is influenced by standard margin paints, so the photoacoustic beacon proved more useful under current tissue-handling protocols.
© 2013 Optical Society of America
Full Article | PDF ArticleMore Like This
Ken Y. Foo, Kelsey M. Kennedy, Renate Zilkens, Wes M. Allen, Qi Fang, Rowan W. Sanderson, James Anstie, Benjamin F. Dessauvagie, Bruce Latham, Christobel M. Saunders, Lixin Chin, and Brendan F. Kennedy
Biomed. Opt. Express 12(3) 1666-1682 (2021)
Wes M. Allen, Ken Y. Foo, Renate Zilkens, Kelsey M. Kennedy, Qi Fang, Lixin Chin, Benjamin F. Dessauvagie, Bruce Latham, Christobel M. Saunders, and Brendan F. Kennedy
Biomed. Opt. Express 9(12) 6331-6349 (2018)
Lisanne L. de Boer, Benno H. W. Hendriks, Frederieke van Duijnhoven, Marie-Jeanne T. F. D. Vrancken Peeters-Baas, Koen Van de Vijver, Claudette E. Loo, Katarzyna Jóźwiak, Henricus J. C. M. Sterenborg, and Theo J. M. Ruers
Biomed. Opt. Express 7(12) 5188-5200 (2016)