Abstract

We report the use of a common path phase sensitive spectral domain optical coherence tomography setup for the measurement of the refractive index (RI) of a biomimetic material (glucose solution in water having intralipid as the scattering medium) and a single biological cell (keratinocyte). The RI of glucose solutions could be measured with a precision of 0.00015, which corresponds to a precision of 2nm in the optical path length measurement in our setup. The precision obtained in the measurement of the RI of a single keratinocyte cell was 0.0004.

© 2011 Optical Society of America

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