Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Multispectral quantitative photoacoustic imaging of osteoarthritis in finger joints

Not Accessible

Your library or personal account may give you access

Abstract

We present in vivo experimental evidence that multispectral quantitative photoacoustic tomography (qPAT) has the potential to detect osteoarthritis (OA) in the finger joints. In this pilot study, two OA patients and three healthy volunteers were enrolled, and their distal interphalangeal (DIP) joints were examined photoacoustically by a multispectral PAT scanner. Images of tissue physiological/functional parameters including oxyhemoglobin, deoxyhemoglobin, oxygen saturation, and water content, along with the tissue acoustic velocity of all the examined joints, were simultaneously recovered using a finite element reconstruction algorithm for multispectral photoacoustic measurements. The recovered multispectral photoacoustic images show that the OA joints have significantly elevated water content, decreased oxygen saturation, and increased acoustic velocity compared to the normal joints.

© 2010 Optical Society of America

Full Article  |  PDF Article
More Like This
Quantitative two-dimensional photoacoustic tomography of osteoarthritis in the finger joints

Jiaying Xiao, Lei Yao, Yao Sun, Eric S. Sobel, Jishan He, and Huabei Jiang
Opt. Express 18(14) 14359-14365 (2010)

Image-guided optical spectroscopy in diagnosis of osteoarthritis: a clinical study

Zhen Yuan, Qizhi Zhang, Eric S. Sobel, and Huabei Jiang
Biomed. Opt. Express 1(1) 74-86 (2010)

Multispectral, non-contact diffuse optical tomography of healthy human finger joints

Daniel Lighter, James Hughes, Iain Styles, Andrew Filer, and Hamid Dehghani
Biomed. Opt. Express 9(4) 1445-1460 (2018)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (7)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved