Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Performance of single-scattering model versus multiple-scattering model in the determination of optical properties of biological tissue with optical coherence tomography

Not Accessible

Your library or personal account may give you access

Abstract

Tissue optical properties can be determined with optical coherence tomography (OCT) by fitting a model to the OCT signal. Using calibrated samples in the fixed focus geometry, the validity of the single-scattering and multiple-scattering models for both highly scattering and weakly scattering media (scattering coefficients μs ranging from 1.25 to 25.11mm1) has been investigated. The results show that, with a proper correction for the confocal properties of the sample arm, both models are appropriate to extract the scattering coefficients of weakly scattering media. For highly scattering media, the multiple scattering should be taken into account, and the multiple-scattering model can provide higher accuracy. Finally, the scattering properties of in vitro rat liver and in vivo human skin are determined. The results are useful for quantitatively characterizing tissue scattering in biomedical research and clinical diagnosis.

© 2010 Optical Society of America

Full Article  |  PDF Article
More Like This
Speckle properties of the logarithmically transformed signal in optical coherence tomography

Peng Lee, Wanrong Gao, and Xianling Zhang
J. Opt. Soc. Am. A 28(4) 517-522 (2011)

Quantitative evaluation of scattering in optical coherence tomography skin images using the extended Huygens–Fresnel theorem

Mohammad R. N. Avanaki, Adrian Gh. Podoleanu, John B. Schofield, Carole Jones, Manu Sira, Yan Liu, and Ali Hojjat
Appl. Opt. 52(8) 1574-1580 (2013)

Quantitative measurement of attenuation coefficients of weakly scattering media using optical coherence tomography

Dirk J. Faber, Freek J. van der Meer, Maurice C.G. Aalders, and Ton G. van Leeuwen
Opt. Express 12(19) 4353-4365 (2004)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (7)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Tables (1)

You do not have subscription access to this journal. Article tables are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Equations (8)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved