In this paper we present spatially mapped point-spread function (PSF) measurements of an optical coherence tomography (OCT) instrument and subsequent spatial deconvolution. The OCT B-scan image plane was divided into 2400 subimages, for which PSFs were determined from OCT measurements of a specially designed phantom. Each PSF was deconvolved from its corresponding subimage of the phantom using the Lucy–Richardson algorithm. Following deconvolution, all of the subimages were reassembled to form a final deconvolved image, from which the resolution improvement was quantitatively assessed. The lateral resolution was found to improve by compared to an axial resolution enhancement of . The spatial uniformity of both axial and lateral resolution was also observed to increase following deconvolution, demonstrating the advantage of deconvolving local PSFs from their associated subimages.
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