Abstract

We investigated the effects of operator-applied force on diffuse optical spectroscopy (DOS) by integrating a force transducer into the handheld probe. Over the typical range of contact forces measured in the breasts of eight patients, absorption and reduced scattering coefficients (650 to 1000nm) variance was 3.1±1.0% and 1.0±0.4%. For trained operators, we observed <5% variation in hemoglobin and <2% variation in water and lipids. Contact force is not a significant source of variation, most likely because of a relatively wide probe surface area and the stability of the DOS method for calculating tissue optical properties.

© 2009 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Hemodynamic signature of breast cancer under fractional mammographic compression using a dynamic diffuse optical tomography system

Stefan A. Carp, Amir Y. Sajjadi, Christy M. Wanyo, Qianqian Fang, Michelle C. Specht, Lidia Schapira, Beverly Moy, Aditya Bardia, David A. Boas, and Steven J. Isakoff
Biomed. Opt. Express 4(12) 2911-2924 (2013)

Dynamic schema for near infrared detection of pressure-induced changes in solid tumors

Bei Wang, Stephen P. Povoski, Xianhua Cao, Duxin Sun, and Ronald X. Xu
Appl. Opt. 47(16) 3053-3063 (2008)

Dynamic functional and mechanical response of breast tissue to compression

S. A. Carp, J. Selb, Q. Fang, R. Moore, D. B. Kopans, E. Rafferty, and D. A. Boas
Opt. Express 16(20) 16064-16078 (2008)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (6)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Tables (1)

You do not have subscription access to this journal. Article tables are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription