Abstract

Diffuse optical tomography (DOT) is a potential new imaging modality to detect or monitor breast lesions. Recently, Philips developed a new DOT system capable of transmission and fluorescence imaging, where the investigated breast is hanging freely into the measurement cup containing scattering fluid. We present a fast and robust image reconstruction algorithm that is used for the transmission measurements. The algorithm is based on the Rytov approximation. We show that this algorithm can be used over a wide range of tissue optical properties if the reconstruction is adapted to each patient. We use estimates of the breast shape and average tissue optical properties to initialize the reconstruction, which improves the image quality significantly. We demonstrate the capability of the measurement system and reconstruction to image breast lesions by clinical examples.

© 2008 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Three-dimensional time-resolved optical mammography of the uncompressed breast

Louise C. Enfield, Adam P. Gibson, Nicholas L. Everdell, David T. Delpy, Martin Schweiger, Simon R. Arridge, Caroline Richardson, Mohammad Keshtgar, Michael Douek, and Jeremy C. Hebden
Appl. Opt. 46(17) 3628-3638 (2007)

Monitoring recovery after laser surgery of the breast with optical tomography: a case study

Jeremy C. Hebden, Tara D. Yates, Adam Gibson, Nicholas Everdell, Simon R. Arridge, Dennis W. Chicken, Michael Douek, and Mohammed R. S. Keshtgar
Appl. Opt. 44(10) 1898-1904 (2005)

Visualizing breast cancer using the Twente photoacoustic mammoscope: What do we learn from twelve new patient measurements?

M. Heijblom, D. Piras, W. Xia, J.C.G. van Hespen, J.M. Klaase, F.M. van den Engh, T.G. van Leeuwen, W. Steenbergen, and S. Manohar
Opt. Express 20(11) 11582-11597 (2012)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (11)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (18)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription