Abstract

We report chemical imaging using Fourier transform coherent anti-Stokes Raman scattering (FTCARS) microscopy. Adding a passively phase-stable local field to amplify the weak FTCARS signal, we also demonstrate interferometric FTCARS microscopy, permitting reduced incident power to be used for imaging. We discuss signal-to-noise considerations and the conditions necessary to effectively suppress background noise, allowing FTCARS microscopy that is limited by the shot noise of the detector. We also discuss differences between the signal-to-noise obtainable by time and frequency domain coherent anti-Stokes Raman scattering (CARS) methods.

© 2008 Optical Society of America

Interferometric Fourier transform coherent anti-stokes Raman scattering

Meng Cui, Manuel Joffre, Joshua Skodack, and Jennifer P. Ogilvie
Opt. Express 14(18) 8448-8458 (2006)

Single-shot interferometric approach to background free broadband coherent anti-Stokes Raman scattering spectroscopy*

Young Jong Lee and Marcus T. Cicerone
Opt. Express 17(1) 123-135 (2009)

Phase-controlled polarization coherent anti-Stokes Raman scattering microscopy for high-sensitivity and high-contrast molecular imaging

Fake Lu, Wei Zheng, and Zhiwei Huang
J. Opt. Soc. Am. B 25(11) 1907-1913 (2008)

Implementation of vibrational phase contrast coherent anti-Stokes Raman scattering microscopy

Martin Jurna, Jennifer L. Herek, and Herman L. Offerhaus
Appl. Opt. 50(13) 1839-1842 (2011)

Quantitative chemical imaging with background-free multiplex coherent anti-Stokes Raman scattering by dual-soliton Stokes pulses

Kun Chen, Tao Wu, Haoyun Wei, Tian Zhou, and Yan Li
Biomed. Opt. Express 7(10) 3927-3939 (2016)