Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Miniature endoscope for simultaneous optical coherence tomography and laser-induced fluorescence measurement

Not Accessible

Your library or personal account may give you access

Abstract

We have designed a multimodality system that combines optical coherence tomography (OCT) and laser-induced fluorescence (LIF) in a 2.0-mm-diameter endoscopic package. OCT provides ∼18-μm resolution cross-sectional structural information over a 6-mm field. LIF spectra are collected sequentially at submillimeter resolution across the same field and provide histochemical information about the tissue. We present the use of a rod prism to reduce the asymmetry in the OCT beam caused by a cylindrical window. The endoscope has been applied to investigate mouse colon cancer in vivo.

© 2004 Optical Society of America

Full Article  |  PDF Article
More Like This
Task-based imaging of colon cancer in the ApcMin/+ mouse model

James B. McNally, Nathaniel D. Kirkpatrick, Lida P. Hariri, Alexandre R. Tumlinson, David G. Besselsen, Eugene W. Gerner, Urs Utzinger, and Jennifer K. Barton
Appl. Opt. 45(13) 3049-3062 (2006)

Novel focused OCT-LIF endoscope

R. Andrew Wall, Garret T. Bonnema, and Jennifer K. Barton
Biomed. Opt. Express 2(3) 421-430 (2011)

Fluorescence-guided optical coherence tomography imaging for colon cancer screening: a preliminary mouse study

Nicusor Iftimia, Arun K. Iyer, Daniel X. Hammer, Niyom Lue, Mircea Mujat, Martha Pitman, R. Daniel Ferguson, and Mansoor Amiji
Biomed. Opt. Express 3(1) 178-191 (2012)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (6)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Tables (2)

You do not have subscription access to this journal. Article tables are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved