Abstract

The accuracy of the perturbation model to predict the effect of scattering and absorbing inhomogeneities on photon migration has been investigated by comparisons with experimental and numerical results. Comparisons for scattering inhomogeneities showed that the model gives satisfactory results both for the intensity and for the temporal profile of the perturbation over a large range of values for the scattering properties of the defect. As for absorbing inhomogeneities, the model provides an excellent description for the temporal profile, but the results for the intensity are accurate only when the perturbation is small. For absorbing inhomogeneities an empirical model that has a significantly more extended application range has been proposed. The model is based on an expression for the time-resolved mean path length that detected photons have followed inside the inhomogeneity. The application range of the proposed model covers the values expected for the optical properties and for the volumes of inhomogeneities of practical interest for optical mammography.

© 2001 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Monte Carlo procedure for investigating light propagation and imaging of highly scattering media

Angelo Sassaroli, Costantino Blumetti, Fabrizio Martelli, Lucia Alianelli, Daniele Contini, Andrea Ismaelli, and Giovanni Zaccanti
Appl. Opt. 37(31) 7392-7400 (1998)

Perturbation approach to the time-resolved transmittance for a spatially varying scattering inclusion in a diffusive slab

Rosario Esposito, Sergio De Nicola, Maria Lepore, and Pietro Luigi Indovina
J. Opt. Soc. Am. A 23(8) 1937-1945 (2006)

Forward solvers for photon migration in the presence of highly and totally absorbing objects embedded inside diffusive media

Angelo Sassaroli, Antonio Pifferi, Davide Contini, Alessandro Torricelli, Lorenzo Spinelli, Heidrun Wabnitz, Paola Di Ninni, Giovanni Zaccanti, and Fabrizio Martelli
J. Opt. Soc. Am. A 31(3) 460-469 (2014)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (13)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (15)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription