Abstract

The hit–miss transform serves as a region-of-interest locator for cells from cervical smear images that show abnormal changes, which are indicative of malignancy, in their nuclei. An optical implementation of the hit–miss transform algorithm uses an analog spatial light modulator for gray-scale modulation at the filter plane of a 4f optical correlator. Gray-scale modulation at the filter plane improves correlator performance in comparison with a binary phase-only filter (BPOF) by reduction of the edge enhancement of kernels used in morphological detection of cancerous cervical cells. The hit–miss transform with a gray-scale amplitude and binary phase optical filter (GABPOF) for the hit filter and a BPOF for the miss filter shows a 47% reduction in total error versus the use of only BPOF filters to locate abnormal cells.

© 2000 Optical Society of America

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