Abstract

Photoacoustic signal generation can be used for a new medical tomographic technique. This makes it possible to image optically different structures, such as the (micro)vascular system in tissues, by use of a transducer array for the detection of laser-generated wide-bandwidth ultrasound. A time-domain delay-and-sum focused beam-forming technique is used to locate the photoacoustic sources in the sample. To characterize the transducer response, simulations have been performed for a wide variety of parameter values and have been verified experimentally. With these data the weight factors for the spectrally and temporally filtered sensor signals are determined in order to optimize the signal-to-noise ratio of the beam former. The imaging algorithm is investigated by simulations and experiments. With this algorithm, for what is to our knowledge the first time, the three-dimensional photoacoustic imaging of complex optically absorbing structures located in a highly diffuse medium is demonstrated. When 200-µm-diameter hydrophone elements are used, the depth resolution is better than 20 µm, and the lateral resolution is better than 200 µm, independent of the depth for our range of imaging (to ∼6 mm). Reduction of the transducer diameters and adaptation of the weight factors, at the cost of some increase of the noise level, will further improve the lateral resolution. The synthetic aperture algorithm used has been shown to be suitable for the new technique of photoacoustic tissue scanning.

© 2000 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
All-optical highly sensitive akinetic sensor for ultrasound detection and photoacoustic imaging

Stefan Preisser, Wolfgang Rohringer, Mengyang Liu, Christian Kollmann, Stefan Zotter, Balthasar Fischer, and Wolfgang Drexler
Biomed. Opt. Express 7(10) 4171-4186 (2016)

Low cost, high performance white-light fiber-optic hydrophone system with a trackable working point

Jinyu Ma, Meirong Zhao, Xinjing Huang, Hyungdae Bae, Yongyao Chen, and Miao Yu
Opt. Express 24(17) 19008-19019 (2016)

Fast full-view photoacoustic imaging by combined scanning with a linear transducer array

Diwu Yang, Da Xing, Sihua Yang, and Liangzhong Xiang
Opt. Express 15(23) 15566-15575 (2007)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (9)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (22)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription