Abstract

We have developed a laser-pulse mammograph capable of recording optical mammograms within ∼3 min by measuring time-resolved transmittance at each of typically 1500 scan positions, 2.5 mm apart. As a first application two patients who have tumors were investigated successfully. From measured distributions of times of flight of photons corrected for edge effects we derived (1) characteristic quantities, such as photon counts in selected time windows, to generate optical mammograms; (2) effective transport scattering and absorption coefficients of breast tissue at each scan position, assuming the breast to be homogeneous; and (3) optical properties of a selected tumor by applying the theory of diffraction of photon density waves by spherical inhomogeneity. Mammograms recorded at different lateral offsets between source and detector fiber were used to estimate the depth of inhomogeneities.

© 1999 Optical Society of America

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    [CrossRef] [PubMed]
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    [CrossRef] [PubMed]

1998 (5)

1997 (5)

D. A. Boas, M. A. O’Leary, B. Chance, A. Yodh, “Detection and characterization of optical inhomogeneities with diffuse photon density waves: a signal-to-noise analysis,” Appl. Opt. 36, 75–92 (1997).
[CrossRef] [PubMed]

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

H. Wabnitz, H. Rinneberg, “Imaging in turbid media by photon density waves: spatial resolution and scaling relations,” Appl. Opt. 36, 64–74 (1997).
[CrossRef] [PubMed]

M. A. Franceschini, K. T. Moesta, S. Fantini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, M. Seeber, P. M. Schlag, M. Kaschke, “Frequency-domain techniques enhance optical mammography: initial clinical results,” Proc. Natl. Acad. Sci. USA 94, 6468–6473 (1997).
[CrossRef] [PubMed]

B. J. Tromberg, O. Coquoz, J. B. Fishkin, T. Pham, E. R. Anderson, J. Butler, M. Cahn, J. D. Gross, V. Venugopalan, D. Pham, “Noninvasive measurements of breast tissue optical properties using frequency-domain photon migration,” Philos. Trans. R. Soc. London Ser. B 352, 661–668 (1997).
[CrossRef]

1996 (6)

H. Heusmann, J. Kölzer, G. Mitic, “Characterization of female breasts in vivo by time-resolved and spectroscopic measurements in near infrared spectroscopy,” J. Biomed. Opt. 1, 425–434 (1996).
[CrossRef] [PubMed]

S. Fantini, M. A. Franceschini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, K. T. Moesta, P. M. Schlag, M. Kaschke, “Frequency-domain optical mammography: edge effect corrections,” Med. Phys. 23, 149–157 (1996).
[CrossRef] [PubMed]

K. Suzuki, Y. Yamashita, K. Ohta, M. Kaneko, M. Yoshida, B. Chance, “Quantitative measurement of optical parameters in normal breasts using time-resolved spectroscopy: in vivo results of 30 Japanese women,” J. Biomed. Opt. 1, 330–334 (1996).
[CrossRef] [PubMed]

T. L. Troy, D. L. Page, E. M. Sevick-Muraca, “Optical properties of normal and diseased breast tissues: prognosis for optical mammography,” J. Biomed. Opt. 1, 342–355 (1996).
[CrossRef] [PubMed]

R. Berg, S. Andersson-Engels, O. Jarlman, S. Svanberg, “Time-gated viewing studies on tissuelike phantoms,” Appl. Opt. 35, 3432–3440 (1996).
[CrossRef] [PubMed]

X. D. Li, M. A. O’Leary, D. A. Boas, B. Chance, A. G. Yodh, “Fluorescent diffuse photon density waves in homogeneous and heterogeneous turbid media: analytic solutions and applications,” Appl. Opt. 35, 3746–3758 (1996).
[CrossRef] [PubMed]

1995 (1)

1994 (4)

G. Mitic, J. Kölzer, J. Otto, E. Plies, G. Sölkner, W. Zinth, “Time-gated transillumination of biological tissues and tissuelike phantoms,” Appl. Opt. 33, 6699–6710 (1994).
[CrossRef] [PubMed]

R. C. Haskell, L. O. Svaasand, T.-T. Tsay, T.-C. Feng, M. S. McAdams, B. J. Tromberg, “Boundary conditions for the diffusion equation in radiative transfer,” J. Opt. Soc. Am. A 11, 2727–2741 (1994).
[CrossRef]

S. Nioka, M. Miwa, S. Orel, M. Schnall, M. Haida, S. Zhao, B. Chance, “Optical imaging of human breast cancer,” Adv. Exp. Med. Biol. 361, 171–179 (1994).
[CrossRef] [PubMed]

D. A. Boas, M. A. O’Leary, B. Chance, A. G. Yodh, “Scattering of diffuse photon density waves by spherical inhomogeneities within turbid media: analytic solution and applications,” Proc. Natl. Acad. Sci. USA 91, 4887–4891 (1994).
[CrossRef] [PubMed]

1992 (1)

S. R. Arridge, M. Cope, D. T. Delpy, “The theoretical basis for the determination of optical path lengths in tissues: temporal and frequency analysis,” Phys. Med. Biol. 37, 1531–1560 (1992).
[CrossRef] [PubMed]

1990 (2)

J. C. Hebden, R. A. Kruger, “Transillumination imaging performance: spatial resolution simulation studies,” Med. Phys. 17, 41–47 (1990).
[CrossRef] [PubMed]

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

1989 (1)

’t Hooft, G. W.

J. H. Hoogenraad, M. B. van der Mark, S. B. Colak, G. W. ’t Hooft, E. S. van der Linden, “First results from the Philips optical mammoscope,” in Photon Propagation in Tissues III, D. A. Benaron, B. Chance, M. Ferrari, eds., Proc. SPIE3194, 184–190 (1997).

Åkesson, P.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Albagli, D.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Alveryd, A.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Anderson, E. R.

B. J. Tromberg, O. Coquoz, J. B. Fishkin, T. Pham, E. R. Anderson, J. Butler, M. Cahn, J. D. Gross, V. Venugopalan, D. Pham, “Noninvasive measurements of breast tissue optical properties using frequency-domain photon migration,” Philos. Trans. R. Soc. London Ser. B 352, 661–668 (1997).
[CrossRef]

Andersson, I.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Andersson-Engels, S.

Arridge, S. R.

S. R. Arridge, M. Cope, D. T. Delpy, “The theoretical basis for the determination of optical path lengths in tissues: temporal and frequency analysis,” Phys. Med. Biol. 37, 1531–1560 (1992).
[CrossRef] [PubMed]

Aspegren, K.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Balldin, G.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Berg, R.

Bjurstam, N.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Boas, D. A.

Butler, J.

B. J. Tromberg, O. Coquoz, J. B. Fishkin, T. Pham, E. R. Anderson, J. Butler, M. Cahn, J. D. Gross, V. Venugopalan, D. Pham, “Noninvasive measurements of breast tissue optical properties using frequency-domain photon migration,” Philos. Trans. R. Soc. London Ser. B 352, 661–668 (1997).
[CrossRef]

Cahn, M.

B. J. Tromberg, O. Coquoz, J. B. Fishkin, T. Pham, E. R. Anderson, J. Butler, M. Cahn, J. D. Gross, V. Venugopalan, D. Pham, “Noninvasive measurements of breast tissue optical properties using frequency-domain photon migration,” Philos. Trans. R. Soc. London Ser. B 352, 661–668 (1997).
[CrossRef]

Castleberry, D. E.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Chance, B.

D. A. Boas, M. A. O’Leary, B. Chance, A. Yodh, “Detection and characterization of optical inhomogeneities with diffuse photon density waves: a signal-to-noise analysis,” Appl. Opt. 36, 75–92 (1997).
[CrossRef] [PubMed]

X. D. Li, M. A. O’Leary, D. A. Boas, B. Chance, A. G. Yodh, “Fluorescent diffuse photon density waves in homogeneous and heterogeneous turbid media: analytic solutions and applications,” Appl. Opt. 35, 3746–3758 (1996).
[CrossRef] [PubMed]

K. Suzuki, Y. Yamashita, K. Ohta, M. Kaneko, M. Yoshida, B. Chance, “Quantitative measurement of optical parameters in normal breasts using time-resolved spectroscopy: in vivo results of 30 Japanese women,” J. Biomed. Opt. 1, 330–334 (1996).
[CrossRef] [PubMed]

S. Nioka, M. Miwa, S. Orel, M. Schnall, M. Haida, S. Zhao, B. Chance, “Optical imaging of human breast cancer,” Adv. Exp. Med. Biol. 361, 171–179 (1994).
[CrossRef] [PubMed]

D. A. Boas, M. A. O’Leary, B. Chance, A. G. Yodh, “Scattering of diffuse photon density waves by spherical inhomogeneities within turbid media: analytic solution and applications,” Proc. Natl. Acad. Sci. USA 91, 4887–4891 (1994).
[CrossRef] [PubMed]

M. S. Patterson, B. Chance, B. C. Wilson, “Time resolved reflectance and transmittance for the noninvasive measurement of tissue optical properties,” Appl. Opt. 28, 2331–2336 (1989).
[CrossRef] [PubMed]

V. Ntziachristos, X. Ma, M. Schnall, B. Chance, “A multichannel single photon counting NIR imager for coregistration with MRI,” in Photon Propagation in Tissues III, D. A. Benaron, B. Chance, M. Ferrari, eds., Proc. SPIE3194, 219–227 (1997).

Chernomordik, V.

Christian, B. T.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Colak, S. B.

J. H. Hoogenraad, M. B. van der Mark, S. B. Colak, G. W. ’t Hooft, E. S. van der Linden, “First results from the Philips optical mammoscope,” in Photon Propagation in Tissues III, D. A. Benaron, B. Chance, M. Ferrari, eds., Proc. SPIE3194, 184–190 (1997).

Cope, M.

S. R. Arridge, M. Cope, D. T. Delpy, “The theoretical basis for the determination of optical path lengths in tissues: temporal and frequency analysis,” Phys. Med. Biol. 37, 1531–1560 (1992).
[CrossRef] [PubMed]

Coquoz, O.

B. J. Tromberg, O. Coquoz, J. B. Fishkin, T. Pham, E. R. Anderson, J. Butler, M. Cahn, J. D. Gross, V. Venugopalan, D. Pham, “Noninvasive measurements of breast tissue optical properties using frequency-domain photon migration,” Philos. Trans. R. Soc. London Ser. B 352, 661–668 (1997).
[CrossRef]

Cubeddu, R.

Danlewski, H.

H. Danlewski, “Physikalische Grundlagen der zeitaufgelösten optischen Mammographie einschliesslich Anwendungen,” Ph.D. dissertation (Freie Universität Berlin, Berlin, 1998).

DeJule, M. C.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Delpy, D. T.

J. C. Hebden, D. J. Hall, M. Firbank, D. T. Delpy, “Time-resolved optical imaging of a solid tissue-equivalent phantom,” Appl. Opt. 34, 8038–8047 (1995).
[CrossRef] [PubMed]

S. R. Arridge, M. Cope, D. T. Delpy, “The theoretical basis for the determination of optical path lengths in tissues: temporal and frequency analysis,” Phys. Med. Biol. 37, 1531–1560 (1992).
[CrossRef] [PubMed]

Edström, G.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Fagerberg, G.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Fantini, S.

S. Fantini, S. A. Walker, M. A. Franceschini, M. Kaschke, P. M. Schlag, K. T. Moesta, “Assessment of the size, position, and optical properties of breast tumors in vivo by noninvasive optical methods,” Appl. Opt. 37, 1982–1989 (1998).
[CrossRef]

M. A. Franceschini, K. T. Moesta, S. Fantini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, M. Seeber, P. M. Schlag, M. Kaschke, “Frequency-domain techniques enhance optical mammography: initial clinical results,” Proc. Natl. Acad. Sci. USA 94, 6468–6473 (1997).
[CrossRef] [PubMed]

S. Fantini, M. A. Franceschini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, K. T. Moesta, P. M. Schlag, M. Kaschke, “Frequency-domain optical mammography: edge effect corrections,” Med. Phys. 23, 149–157 (1996).
[CrossRef] [PubMed]

Feng, T.-C.

Ferrari, M.

V. Quaresima, S. J. Matcher, M. Ferrari, “Identification and quantification of intrinsic optical contrast for near-infrared mammography,” Photochem. Photobiol. 67, 4–14 (1998).
[CrossRef] [PubMed]

Firbank, M.

Fishkin, J. B.

B. J. Tromberg, O. Coquoz, J. B. Fishkin, T. Pham, E. R. Anderson, J. Butler, M. Cahn, J. D. Gross, V. Venugopalan, D. Pham, “Noninvasive measurements of breast tissue optical properties using frequency-domain photon migration,” Philos. Trans. R. Soc. London Ser. B 352, 661–668 (1997).
[CrossRef]

Fitzgerald, P. F.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Fobare, D. F.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Franceschini, M. A.

S. Fantini, S. A. Walker, M. A. Franceschini, M. Kaschke, P. M. Schlag, K. T. Moesta, “Assessment of the size, position, and optical properties of breast tumors in vivo by noninvasive optical methods,” Appl. Opt. 37, 1982–1989 (1998).
[CrossRef]

M. A. Franceschini, K. T. Moesta, S. Fantini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, M. Seeber, P. M. Schlag, M. Kaschke, “Frequency-domain techniques enhance optical mammography: initial clinical results,” Proc. Natl. Acad. Sci. USA 94, 6468–6473 (1997).
[CrossRef] [PubMed]

S. Fantini, M. A. Franceschini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, K. T. Moesta, P. M. Schlag, M. Kaschke, “Frequency-domain optical mammography: edge effect corrections,” Med. Phys. 23, 149–157 (1996).
[CrossRef] [PubMed]

Gaida, G.

M. A. Franceschini, K. T. Moesta, S. Fantini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, M. Seeber, P. M. Schlag, M. Kaschke, “Frequency-domain techniques enhance optical mammography: initial clinical results,” Proc. Natl. Acad. Sci. USA 94, 6468–6473 (1997).
[CrossRef] [PubMed]

S. Fantini, M. A. Franceschini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, K. T. Moesta, P. M. Schlag, M. Kaschke, “Frequency-domain optical mammography: edge effect corrections,” Med. Phys. 23, 149–157 (1996).
[CrossRef] [PubMed]

Gandjbakhche, A. H.

Giambattista, B. W.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Giardino, A. A.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Glas, U.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Götz, L.

L. Götz, S. H. Heywang-Köbrunner, O. Schütz, H. Siebold, “Optical mammography on preoperative patients,” Akt. Radiol. 8, 31–33 (1998).

Gratton, E.

M. A. Franceschini, K. T. Moesta, S. Fantini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, M. Seeber, P. M. Schlag, M. Kaschke, “Frequency-domain techniques enhance optical mammography: initial clinical results,” Proc. Natl. Acad. Sci. USA 94, 6468–6473 (1997).
[CrossRef] [PubMed]

S. Fantini, M. A. Franceschini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, K. T. Moesta, P. M. Schlag, M. Kaschke, “Frequency-domain optical mammography: edge effect corrections,” Med. Phys. 23, 149–157 (1996).
[CrossRef] [PubMed]

Gross, J. D.

B. J. Tromberg, O. Coquoz, J. B. Fishkin, T. Pham, E. R. Anderson, J. Butler, M. Cahn, J. D. Gross, V. Venugopalan, D. Pham, “Noninvasive measurements of breast tissue optical properties using frequency-domain photon migration,” Philos. Trans. R. Soc. London Ser. B 352, 661–668 (1997).
[CrossRef]

Haida, M.

S. Nioka, M. Miwa, S. Orel, M. Schnall, M. Haida, S. Zhao, B. Chance, “Optical imaging of human breast cancer,” Adv. Exp. Med. Biol. 361, 171–179 (1994).
[CrossRef] [PubMed]

Hall, D. J.

Hallberg, D.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Haskell, R. C.

Hebden, J. C.

Heusmann, H.

H. Heusmann, J. Kölzer, G. Mitic, “Characterization of female breasts in vivo by time-resolved and spectroscopic measurements in near infrared spectroscopy,” J. Biomed. Opt. 1, 425–434 (1996).
[CrossRef] [PubMed]

Heywang-Köbrunner, S. H.

L. Götz, S. H. Heywang-Köbrunner, O. Schütz, H. Siebold, “Optical mammography on preoperative patients,” Akt. Radiol. 8, 31–33 (1998).

Hoogenraad, J. H.

J. H. Hoogenraad, M. B. van der Mark, S. B. Colak, G. W. ’t Hooft, E. S. van der Linden, “First results from the Philips optical mammoscope,” in Photon Propagation in Tissues III, D. A. Benaron, B. Chance, M. Ferrari, eds., Proc. SPIE3194, 184–190 (1997).

Jarlman, O.

R. Berg, S. Andersson-Engels, O. Jarlman, S. Svanberg, “Time-gated viewing studies on tissuelike phantoms,” Appl. Opt. 35, 3432–3440 (1996).
[CrossRef] [PubMed]

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Jess, H.

M. A. Franceschini, K. T. Moesta, S. Fantini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, M. Seeber, P. M. Schlag, M. Kaschke, “Frequency-domain techniques enhance optical mammography: initial clinical results,” Proc. Natl. Acad. Sci. USA 94, 6468–6473 (1997).
[CrossRef] [PubMed]

S. Fantini, M. A. Franceschini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, K. T. Moesta, P. M. Schlag, M. Kaschke, “Frequency-domain optical mammography: edge effect corrections,” Med. Phys. 23, 149–157 (1996).
[CrossRef] [PubMed]

Kaneko, M.

K. Suzuki, Y. Yamashita, K. Ohta, M. Kaneko, M. Yoshida, B. Chance, “Quantitative measurement of optical parameters in normal breasts using time-resolved spectroscopy: in vivo results of 30 Japanese women,” J. Biomed. Opt. 1, 330–334 (1996).
[CrossRef] [PubMed]

Kaschke, M.

S. Fantini, S. A. Walker, M. A. Franceschini, M. Kaschke, P. M. Schlag, K. T. Moesta, “Assessment of the size, position, and optical properties of breast tumors in vivo by noninvasive optical methods,” Appl. Opt. 37, 1982–1989 (1998).
[CrossRef]

M. A. Franceschini, K. T. Moesta, S. Fantini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, M. Seeber, P. M. Schlag, M. Kaschke, “Frequency-domain techniques enhance optical mammography: initial clinical results,” Proc. Natl. Acad. Sci. USA 94, 6468–6473 (1997).
[CrossRef] [PubMed]

S. Fantini, M. A. Franceschini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, K. T. Moesta, P. M. Schlag, M. Kaschke, “Frequency-domain optical mammography: edge effect corrections,” Med. Phys. 23, 149–157 (1996).
[CrossRef] [PubMed]

Kölzer, J.

H. Heusmann, J. Kölzer, G. Mitic, “Characterization of female breasts in vivo by time-resolved and spectroscopic measurements in near infrared spectroscopy,” J. Biomed. Opt. 1, 425–434 (1996).
[CrossRef] [PubMed]

G. Mitic, J. Kölzer, J. Otto, E. Plies, G. Sölkner, W. Zinth, “Time-gated transillumination of biological tissues and tissuelike phantoms,” Appl. Opt. 33, 6699–6710 (1994).
[CrossRef] [PubMed]

Kopans, D. B.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Kruger, R. A.

J. C. Hebden, R. A. Kruger, “Transillumination imaging performance: spatial resolution simulation studies,” Med. Phys. 17, 41–47 (1990).
[CrossRef] [PubMed]

Kwasnick, R. F.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Landberg, C. E.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Larsson, S. A.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Li, X. D.

Lidbrink, E.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Lingaas, H.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Liu, J.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Löfgren, M.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Lubowski, S. J.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Ma, X.

V. Ntziachristos, X. Ma, M. Schnall, B. Chance, “A multichannel single photon counting NIR imager for coregistration with MRI,” in Photon Propagation in Tissues III, D. A. Benaron, B. Chance, M. Ferrari, eds., Proc. SPIE3194, 219–227 (1997).

Mantulin, W. W.

M. A. Franceschini, K. T. Moesta, S. Fantini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, M. Seeber, P. M. Schlag, M. Kaschke, “Frequency-domain techniques enhance optical mammography: initial clinical results,” Proc. Natl. Acad. Sci. USA 94, 6468–6473 (1997).
[CrossRef] [PubMed]

S. Fantini, M. A. Franceschini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, K. T. Moesta, P. M. Schlag, M. Kaschke, “Frequency-domain optical mammography: edge effect corrections,” Med. Phys. 23, 149–157 (1996).
[CrossRef] [PubMed]

Matcher, S. J.

V. Quaresima, S. J. Matcher, M. Ferrari, “Identification and quantification of intrinsic optical contrast for near-infrared mammography,” Photochem. Photobiol. 67, 4–14 (1998).
[CrossRef] [PubMed]

McAdams, M. S.

Mitic, G.

H. Heusmann, J. Kölzer, G. Mitic, “Characterization of female breasts in vivo by time-resolved and spectroscopic measurements in near infrared spectroscopy,” J. Biomed. Opt. 1, 425–434 (1996).
[CrossRef] [PubMed]

G. Mitic, J. Kölzer, J. Otto, E. Plies, G. Sölkner, W. Zinth, “Time-gated transillumination of biological tissues and tissuelike phantoms,” Appl. Opt. 33, 6699–6710 (1994).
[CrossRef] [PubMed]

Miwa, M.

S. Nioka, M. Miwa, S. Orel, M. Schnall, M. Haida, S. Zhao, B. Chance, “Optical imaging of human breast cancer,” Adv. Exp. Med. Biol. 361, 171–179 (1994).
[CrossRef] [PubMed]

Moesta, K. T.

S. Fantini, S. A. Walker, M. A. Franceschini, M. Kaschke, P. M. Schlag, K. T. Moesta, “Assessment of the size, position, and optical properties of breast tumors in vivo by noninvasive optical methods,” Appl. Opt. 37, 1982–1989 (1998).
[CrossRef]

M. A. Franceschini, K. T. Moesta, S. Fantini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, M. Seeber, P. M. Schlag, M. Kaschke, “Frequency-domain techniques enhance optical mammography: initial clinical results,” Proc. Natl. Acad. Sci. USA 94, 6468–6473 (1997).
[CrossRef] [PubMed]

S. Fantini, M. A. Franceschini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, K. T. Moesta, P. M. Schlag, M. Kaschke, “Frequency-domain optical mammography: edge effect corrections,” Med. Phys. 23, 149–157 (1996).
[CrossRef] [PubMed]

Moore, R.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Niklason, L. E.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Niklason, L. T.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Nioka, S.

S. Nioka, M. Miwa, S. Orel, M. Schnall, M. Haida, S. Zhao, B. Chance, “Optical imaging of human breast cancer,” Adv. Exp. Med. Biol. 361, 171–179 (1994).
[CrossRef] [PubMed]

Nossal, R.

Ntziachristos, V.

V. Ntziachristos, X. Ma, M. Schnall, B. Chance, “A multichannel single photon counting NIR imager for coregistration with MRI,” in Photon Propagation in Tissues III, D. A. Benaron, B. Chance, M. Ferrari, eds., Proc. SPIE3194, 219–227 (1997).

O’Leary, M. A.

Ohta, K.

K. Suzuki, Y. Yamashita, K. Ohta, M. Kaneko, M. Yoshida, B. Chance, “Quantitative measurement of optical parameters in normal breasts using time-resolved spectroscopy: in vivo results of 30 Japanese women,” J. Biomed. Opt. 1, 330–334 (1996).
[CrossRef] [PubMed]

Opsahl-Ong, B. H.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Orel, S.

S. Nioka, M. Miwa, S. Orel, M. Schnall, M. Haida, S. Zhao, B. Chance, “Optical imaging of human breast cancer,” Adv. Exp. Med. Biol. 361, 171–179 (1994).
[CrossRef] [PubMed]

Otto, J.

Page, D. L.

T. L. Troy, D. L. Page, E. M. Sevick-Muraca, “Optical properties of normal and diseased breast tissues: prognosis for optical mammography,” J. Biomed. Opt. 1, 342–355 (1996).
[CrossRef] [PubMed]

Patterson, M. S.

Pham, D.

B. J. Tromberg, O. Coquoz, J. B. Fishkin, T. Pham, E. R. Anderson, J. Butler, M. Cahn, J. D. Gross, V. Venugopalan, D. Pham, “Noninvasive measurements of breast tissue optical properties using frequency-domain photon migration,” Philos. Trans. R. Soc. London Ser. B 352, 661–668 (1997).
[CrossRef]

Pham, T.

B. J. Tromberg, O. Coquoz, J. B. Fishkin, T. Pham, E. R. Anderson, J. Butler, M. Cahn, J. D. Gross, V. Venugopalan, D. Pham, “Noninvasive measurements of breast tissue optical properties using frequency-domain photon migration,” Philos. Trans. R. Soc. London Ser. B 352, 661–668 (1997).
[CrossRef]

Pifferi, A.

Plies, E.

Possin, G. E.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Quaresima, V.

V. Quaresima, S. J. Matcher, M. Ferrari, “Identification and quantification of intrinsic optical contrast for near-infrared mammography,” Photochem. Photobiol. 67, 4–14 (1998).
[CrossRef] [PubMed]

Richotte, J. F.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Rinneberg, H.

Rudenstam, C.-M.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Samuelsson, L.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Schlag, P. M.

S. Fantini, S. A. Walker, M. A. Franceschini, M. Kaschke, P. M. Schlag, K. T. Moesta, “Assessment of the size, position, and optical properties of breast tumors in vivo by noninvasive optical methods,” Appl. Opt. 37, 1982–1989 (1998).
[CrossRef]

M. A. Franceschini, K. T. Moesta, S. Fantini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, M. Seeber, P. M. Schlag, M. Kaschke, “Frequency-domain techniques enhance optical mammography: initial clinical results,” Proc. Natl. Acad. Sci. USA 94, 6468–6473 (1997).
[CrossRef] [PubMed]

S. Fantini, M. A. Franceschini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, K. T. Moesta, P. M. Schlag, M. Kaschke, “Frequency-domain optical mammography: edge effect corrections,” Med. Phys. 23, 149–157 (1996).
[CrossRef] [PubMed]

Schnall, M.

S. Nioka, M. Miwa, S. Orel, M. Schnall, M. Haida, S. Zhao, B. Chance, “Optical imaging of human breast cancer,” Adv. Exp. Med. Biol. 361, 171–179 (1994).
[CrossRef] [PubMed]

V. Ntziachristos, X. Ma, M. Schnall, B. Chance, “A multichannel single photon counting NIR imager for coregistration with MRI,” in Photon Propagation in Tissues III, D. A. Benaron, B. Chance, M. Ferrari, eds., Proc. SPIE3194, 219–227 (1997).

Schütz, O.

L. Götz, S. H. Heywang-Köbrunner, O. Schütz, H. Siebold, “Optical mammography on preoperative patients,” Akt. Radiol. 8, 31–33 (1998).

Seeber, M.

M. A. Franceschini, K. T. Moesta, S. Fantini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, M. Seeber, P. M. Schlag, M. Kaschke, “Frequency-domain techniques enhance optical mammography: initial clinical results,” Proc. Natl. Acad. Sci. USA 94, 6468–6473 (1997).
[CrossRef] [PubMed]

Sevick-Muraca, E. M.

T. L. Troy, D. L. Page, E. M. Sevick-Muraca, “Optical properties of normal and diseased breast tissues: prognosis for optical mammography,” J. Biomed. Opt. 1, 342–355 (1996).
[CrossRef] [PubMed]

Siebold, H.

L. Götz, S. H. Heywang-Köbrunner, O. Schütz, H. Siebold, “Optical mammography on preoperative patients,” Akt. Radiol. 8, 31–33 (1998).

Slanetz, P. J.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Sölkner, G.

Strender, L.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Suzuki, K.

K. Suzuki, Y. Yamashita, K. Ohta, M. Kaneko, M. Yoshida, B. Chance, “Quantitative measurement of optical parameters in normal breasts using time-resolved spectroscopy: in vivo results of 30 Japanese women,” J. Biomed. Opt. 1, 330–334 (1996).
[CrossRef] [PubMed]

Svaasand, L. O.

Svanberg, S.

Tabàr, L.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Taroni, P.

Taube, A.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Torricelli, A.

Tromberg, B. J.

B. J. Tromberg, O. Coquoz, J. B. Fishkin, T. Pham, E. R. Anderson, J. Butler, M. Cahn, J. D. Gross, V. Venugopalan, D. Pham, “Noninvasive measurements of breast tissue optical properties using frequency-domain photon migration,” Philos. Trans. R. Soc. London Ser. B 352, 661–668 (1997).
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R. C. Haskell, L. O. Svaasand, T.-T. Tsay, T.-C. Feng, M. S. McAdams, B. J. Tromberg, “Boundary conditions for the diffusion equation in radiative transfer,” J. Opt. Soc. Am. A 11, 2727–2741 (1994).
[CrossRef]

Troy, T. L.

T. L. Troy, D. L. Page, E. M. Sevick-Muraca, “Optical properties of normal and diseased breast tissues: prognosis for optical mammography,” J. Biomed. Opt. 1, 342–355 (1996).
[CrossRef] [PubMed]

Tsay, T.-T.

Valentini, G.

van der Linden, E. S.

J. H. Hoogenraad, M. B. van der Mark, S. B. Colak, G. W. ’t Hooft, E. S. van der Linden, “First results from the Philips optical mammoscope,” in Photon Propagation in Tissues III, D. A. Benaron, B. Chance, M. Ferrari, eds., Proc. SPIE3194, 184–190 (1997).

van der Mark, M. B.

J. H. Hoogenraad, M. B. van der Mark, S. B. Colak, G. W. ’t Hooft, E. S. van der Linden, “First results from the Philips optical mammoscope,” in Photon Propagation in Tissues III, D. A. Benaron, B. Chance, M. Ferrari, eds., Proc. SPIE3194, 184–190 (1997).

Venugopalan, V.

B. J. Tromberg, O. Coquoz, J. B. Fishkin, T. Pham, E. R. Anderson, J. Butler, M. Cahn, J. D. Gross, V. Venugopalan, D. Pham, “Noninvasive measurements of breast tissue optical properties using frequency-domain photon migration,” Philos. Trans. R. Soc. London Ser. B 352, 661–668 (1997).
[CrossRef]

Wabnitz, H.

Walker, S. A.

Wallberg, H.

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

Wei, C.-Y.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Wilson, B. C.

Wirth, R. F.

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Yamashita, Y.

K. Suzuki, Y. Yamashita, K. Ohta, M. Kaneko, M. Yoshida, B. Chance, “Quantitative measurement of optical parameters in normal breasts using time-resolved spectroscopy: in vivo results of 30 Japanese women,” J. Biomed. Opt. 1, 330–334 (1996).
[CrossRef] [PubMed]

Yodh, A.

Yodh, A. G.

X. D. Li, M. A. O’Leary, D. A. Boas, B. Chance, A. G. Yodh, “Fluorescent diffuse photon density waves in homogeneous and heterogeneous turbid media: analytic solutions and applications,” Appl. Opt. 35, 3746–3758 (1996).
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D. A. Boas, M. A. O’Leary, B. Chance, A. G. Yodh, “Scattering of diffuse photon density waves by spherical inhomogeneities within turbid media: analytic solution and applications,” Proc. Natl. Acad. Sci. USA 91, 4887–4891 (1994).
[CrossRef] [PubMed]

Yoshida, M.

K. Suzuki, Y. Yamashita, K. Ohta, M. Kaneko, M. Yoshida, B. Chance, “Quantitative measurement of optical parameters in normal breasts using time-resolved spectroscopy: in vivo results of 30 Japanese women,” J. Biomed. Opt. 1, 330–334 (1996).
[CrossRef] [PubMed]

Zhao, S.

S. Nioka, M. Miwa, S. Orel, M. Schnall, M. Haida, S. Zhao, B. Chance, “Optical imaging of human breast cancer,” Adv. Exp. Med. Biol. 361, 171–179 (1994).
[CrossRef] [PubMed]

Zinth, W.

Adv. Exp. Med. Biol. (1)

S. Nioka, M. Miwa, S. Orel, M. Schnall, M. Haida, S. Zhao, B. Chance, “Optical imaging of human breast cancer,” Adv. Exp. Med. Biol. 361, 171–179 (1994).
[CrossRef] [PubMed]

Akt. Radiol. (1)

L. Götz, S. H. Heywang-Köbrunner, O. Schütz, H. Siebold, “Optical mammography on preoperative patients,” Akt. Radiol. 8, 31–33 (1998).

Appl. Opt. (10)

M. S. Patterson, B. Chance, B. C. Wilson, “Time resolved reflectance and transmittance for the noninvasive measurement of tissue optical properties,” Appl. Opt. 28, 2331–2336 (1989).
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G. Mitic, J. Kölzer, J. Otto, E. Plies, G. Sölkner, W. Zinth, “Time-gated transillumination of biological tissues and tissuelike phantoms,” Appl. Opt. 33, 6699–6710 (1994).
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H. Wabnitz, H. Rinneberg, “Imaging in turbid media by photon density waves: spatial resolution and scaling relations,” Appl. Opt. 36, 64–74 (1997).
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R. Cubeddu, A. Pifferi, P. Taroni, A. Torricelli, G. Valentini, “Imaging with diffusing light: an experimental study of the effect of background optical properties,” Appl. Opt. 37, 3564–3573 (1998).
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J. C. Hebden, D. J. Hall, M. Firbank, D. T. Delpy, “Time-resolved optical imaging of a solid tissue-equivalent phantom,” Appl. Opt. 34, 8038–8047 (1995).
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R. Berg, S. Andersson-Engels, O. Jarlman, S. Svanberg, “Time-gated viewing studies on tissuelike phantoms,” Appl. Opt. 35, 3432–3440 (1996).
[CrossRef] [PubMed]

X. D. Li, M. A. O’Leary, D. A. Boas, B. Chance, A. G. Yodh, “Fluorescent diffuse photon density waves in homogeneous and heterogeneous turbid media: analytic solutions and applications,” Appl. Opt. 35, 3746–3758 (1996).
[CrossRef] [PubMed]

D. A. Boas, M. A. O’Leary, B. Chance, A. Yodh, “Detection and characterization of optical inhomogeneities with diffuse photon density waves: a signal-to-noise analysis,” Appl. Opt. 36, 75–92 (1997).
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A. H. Gandjbakhche, V. Chernomordik, J. C. Hebden, R. Nossal, “Time-dependent contrast functions for quantitative imaging in time-resolved transillumination experiments,” Appl. Opt. 37, 1973–1981 (1998).
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S. Fantini, S. A. Walker, M. A. Franceschini, M. Kaschke, P. M. Schlag, K. T. Moesta, “Assessment of the size, position, and optical properties of breast tumors in vivo by noninvasive optical methods,” Appl. Opt. 37, 1982–1989 (1998).
[CrossRef]

Cancer (1)

A. Alveryd, I. Andersson, K. Aspegren, G. Balldin, N. Bjurstam, G. Edström, G. Fagerberg, U. Glas, O. Jarlman, S. A. Larsson, E. Lidbrink, H. Lingaas, M. Löfgren, C.-M. Rudenstam, L. Strender, L. Samuelsson, L. Tabàr, A. Taube, H. Wallberg, P. Åkesson, D. Hallberg, “Light scanning versus mammography for the detection of breast cancer in screening and clinical practice,” Cancer 65, 1671–1677 (1990).
[CrossRef] [PubMed]

J. Biomed. Opt. (3)

K. Suzuki, Y. Yamashita, K. Ohta, M. Kaneko, M. Yoshida, B. Chance, “Quantitative measurement of optical parameters in normal breasts using time-resolved spectroscopy: in vivo results of 30 Japanese women,” J. Biomed. Opt. 1, 330–334 (1996).
[CrossRef] [PubMed]

T. L. Troy, D. L. Page, E. M. Sevick-Muraca, “Optical properties of normal and diseased breast tissues: prognosis for optical mammography,” J. Biomed. Opt. 1, 342–355 (1996).
[CrossRef] [PubMed]

H. Heusmann, J. Kölzer, G. Mitic, “Characterization of female breasts in vivo by time-resolved and spectroscopic measurements in near infrared spectroscopy,” J. Biomed. Opt. 1, 425–434 (1996).
[CrossRef] [PubMed]

J. Opt. Soc. Am. A (1)

Med. Phys. (2)

J. C. Hebden, R. A. Kruger, “Transillumination imaging performance: spatial resolution simulation studies,” Med. Phys. 17, 41–47 (1990).
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S. Fantini, M. A. Franceschini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, K. T. Moesta, P. M. Schlag, M. Kaschke, “Frequency-domain optical mammography: edge effect corrections,” Med. Phys. 23, 149–157 (1996).
[CrossRef] [PubMed]

Philos. Trans. R. Soc. London Ser. B (1)

B. J. Tromberg, O. Coquoz, J. B. Fishkin, T. Pham, E. R. Anderson, J. Butler, M. Cahn, J. D. Gross, V. Venugopalan, D. Pham, “Noninvasive measurements of breast tissue optical properties using frequency-domain photon migration,” Philos. Trans. R. Soc. London Ser. B 352, 661–668 (1997).
[CrossRef]

Photochem. Photobiol. (1)

V. Quaresima, S. J. Matcher, M. Ferrari, “Identification and quantification of intrinsic optical contrast for near-infrared mammography,” Photochem. Photobiol. 67, 4–14 (1998).
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Phys. Med. Biol. (1)

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[CrossRef] [PubMed]

Proc. Natl. Acad. Sci. USA (2)

D. A. Boas, M. A. O’Leary, B. Chance, A. G. Yodh, “Scattering of diffuse photon density waves by spherical inhomogeneities within turbid media: analytic solution and applications,” Proc. Natl. Acad. Sci. USA 91, 4887–4891 (1994).
[CrossRef] [PubMed]

M. A. Franceschini, K. T. Moesta, S. Fantini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, M. Seeber, P. M. Schlag, M. Kaschke, “Frequency-domain techniques enhance optical mammography: initial clinical results,” Proc. Natl. Acad. Sci. USA 94, 6468–6473 (1997).
[CrossRef] [PubMed]

Radiology (1)

L. T. Niklason, B. T. Christian, L. E. Niklason, D. B. Kopans, D. E. Castleberry, B. H. Opsahl-Ong, C. E. Landberg, P. J. Slanetz, A. A. Giardino, R. Moore, D. Albagli, M. C. DeJule, P. F. Fitzgerald, D. F. Fobare, B. W. Giambattista, R. F. Kwasnick, J. Liu, S. J. Lubowski, G. E. Possin, J. F. Richotte, C.-Y. Wei, R. F. Wirth, “Digital tomosynthesis in breast imaging,” Radiology 205, 399–406 (1997).
[PubMed]

Other (3)

H. Danlewski, “Physikalische Grundlagen der zeitaufgelösten optischen Mammographie einschliesslich Anwendungen,” Ph.D. dissertation (Freie Universität Berlin, Berlin, 1998).

V. Ntziachristos, X. Ma, M. Schnall, B. Chance, “A multichannel single photon counting NIR imager for coregistration with MRI,” in Photon Propagation in Tissues III, D. A. Benaron, B. Chance, M. Ferrari, eds., Proc. SPIE3194, 219–227 (1997).

J. H. Hoogenraad, M. B. van der Mark, S. B. Colak, G. W. ’t Hooft, E. S. van der Linden, “First results from the Philips optical mammoscope,” in Photon Propagation in Tissues III, D. A. Benaron, B. Chance, M. Ferrari, eds., Proc. SPIE3194, 184–190 (1997).

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